High Expression of ENO1 and Low Levels of Circulating Anti-ENO1 Autoantibodies in Patients with Myelodysplastic Neoplasms and Acute Myeloid Leukaemia.
Autorzy:
Lincz LF; Haematology Department, Calvary Mater Newcastle, Waratah, NSW 2298, Australia.; University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, Lookout Road, New Lambton, NSW 2305, Australia. Theron DZ; University of Newcastle, University Drive, Callaghan, NSW 2308, Australia. Barry DL; University of Newcastle, University Drive, Callaghan, NSW 2308, Australia. Scorgie FE; Haematology Department, Calvary Mater Newcastle, Waratah, NSW 2298, Australia.; Hunter Medical Research Institute, Lookout Road, New Lambton, NSW 2305, Australia. Sillar J; Haematology Department, Calvary Mater Newcastle, Waratah, NSW 2298, Australia.; University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, Lookout Road, New Lambton, NSW 2305, Australia.; New South Wales Health Pathology, John Hunter Hospital, Lookout Road, New Lambton, NSW 2305, Australia. Sefhore O; Haematology Department, Calvary Mater Newcastle, Waratah, NSW 2298, Australia.; New South Wales Health Pathology, John Hunter Hospital, Lookout Road, New Lambton, NSW 2305, Australia. Enjeti AK; Haematology Department, Calvary Mater Newcastle, Waratah, NSW 2298, Australia.; University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, Lookout Road, New Lambton, NSW 2305, Australia.; New South Wales Health Pathology, John Hunter Hospital, Lookout Road, New Lambton, NSW 2305, Australia. SkeldingKA; University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, Lookout Road, New Lambton, NSW 2305, Australia.
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Źródło:
Cancers [Cancers (Basel)] 2024 Feb 22; Vol. 16 (5). Date of Electronic Publication: 2024 Feb 22.
Calcium/Calmodulin-Stimulated Protein Kinase II (CaMKII): Different Functional Outcomes from Activation, Depending on the Cellular Microenvironment.
Autorzy:
Rostas JAP; School of Biomedical Sciences and Pharmacy, College of Health Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia. SkeldingKA; School of Biomedical Sciences and Pharmacy, College of Health Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
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Źródło:
Cells [Cells] 2023 Jan 23; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 23.
Bone Marrow Microenvironment as a Source of New Drug Targets for the Treatment of Acute Myeloid Leukaemia.
Autorzy:
SkeldingKA; Cancer Cell Biology Research Group, School of Biomedical Sciences and Pharmacy, College of Health Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia. Barry DL; Cancer Cell Biology Research Group, School of Biomedical Sciences and Pharmacy, College of Health Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia. Theron DZ; Cancer Cell Biology Research Group, School of Biomedical Sciences and Pharmacy, College of Health Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia. Lincz LF; Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.; Hunter Hematology Research Group, Calvary Mater Newcastle Hospital, Waratah, NSW 2298, Australia.
PARP Inhibitors and Haematological Malignancies-Friend or Foe?
Autorzy:
SkeldingKA; Cancer Cell Biology Research Group, School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia. Lincz LF; Cancer Cell Biology Research Group, School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, NSW 2308, Australia.; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.; Hunter Haematology Research Group, Calvary Mater Newcastle Hospital, Waratah, NSW 2298, Australia.
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Źródło:
Cancers [Cancers (Basel)] 2021 Oct 23; Vol. 13 (21). Date of Electronic Publication: 2021 Oct 23.
The Multi-Functional Calcium/Calmodulin Stimulated Protein Kinase (CaMK) Family: Emerging Targets for Anti-Cancer Therapeutic Intervention.
Autorzy:
Brzozowski JS; Priority Research Centre for Cancer Research, Innovation and Translation, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute (HMRI) and University of Newcastle, Callaghan, NSW 2308, Australia. . SkeldingKA; Priority Research Centre for Cancer Research, Innovation and Translation, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute (HMRI) and University of Newcastle, Callaghan, NSW 2308, Australia. Kathryn.Skelding@newcastle.edu.au.
Lipidomic profiling of extracellular vesicles derived from prostate and prostate cancer cell lines.
Autorzy:
Brzozowski JS; School of Biomedical Sciences and Pharmacy, University of Newcastle, Ourimbah, NSW, Australia.; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia. Jankowski H; School of Biomedical Sciences and Pharmacy, University of Newcastle, Ourimbah, NSW, Australia.; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia. Bond DR; School of Biomedical Sciences and Pharmacy, University of Newcastle, Ourimbah, NSW, Australia.; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia. McCague SB; School of Biomedical Sciences and Pharmacy, University of Newcastle, Ourimbah, NSW, Australia.; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia. Munro BR; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW, Australia. Predebon MJ; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW, Australia. Scarlett CJ; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Environmental and Life Sciences, University of Newcastle, Ourimbah, NSW, Australia. SkeldingKA; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia. Weidenhofer J; School of Biomedical Sciences and Pharmacy, University of Newcastle, Ourimbah, NSW, Australia. .; Cancer Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2018 Sep 08; Vol. 17 (1), pp. 211. Date of Electronic Publication: 2018 Sep 08.
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.
Autorzy:
Dewey FE; Regeneron Genetics Center, Tarrytown, NY 10591, USA. . Murray MF; Geisinger Health System, Danville, PA 17822, USA. Overton JD; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Habegger L; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Leader JB; Geisinger Health System, Danville, PA 17822, USA. Fetterolf SN; Geisinger Health System, Danville, PA 17822, USA. O'Dushlaine C; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Van Hout CV; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Staples J; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Gonzaga-Jauregui C; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Metpally R; Geisinger Health System, Danville, PA 17822, USA. Pendergrass SA; Geisinger Health System, Danville, PA 17822, USA. Giovanni MA; Geisinger Health System, Danville, PA 17822, USA. Kirchner HL; Geisinger Health System, Danville, PA 17822, USA. Balasubramanian S; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Abul-Husn NS; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Hartzel DN; Geisinger Health System, Danville, PA 17822, USA. Lavage DR; Geisinger Health System, Danville, PA 17822, USA. Kost KA; Geisinger Health System, Danville, PA 17822, USA. Packer JS; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Lopez AE; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Penn J; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Mukherjee S; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Gosalia N; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Kanagaraj M; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Li AH; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Mitnaul LJ; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Adams LJ; Geisinger Health System, Danville, PA 17822, USA. Person TN; Geisinger Health System, Danville, PA 17822, USA. Praveen K; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Marcketta A; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Lebo MS; Laboratory for Molecular Medicine, Cambridge, MA 02139, USA. Austin-Tse CA; Laboratory for Molecular Medicine, Cambridge, MA 02139, USA. Mason-Suares HM; Laboratory for Molecular Medicine, Cambridge, MA 02139, USA. Bruse S; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Mellis S; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA. Phillips R; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA. Stahl N; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA. Murphy A; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA. Economides A; Regeneron Genetics Center, Tarrytown, NY 10591, USA. SkeldingKA; Geisinger Health System, Danville, PA 17822, USA. Still CD; Geisinger Health System, Danville, PA 17822, USA. Elmore JR; Geisinger Health System, Danville, PA 17822, USA. Borecki IB; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Yancopoulos GD; Regeneron Pharmaceuticals, Tarrytown, NY 10591, USA. Davis FD; Geisinger Health System, Danville, PA 17822, USA. Faucett WA; Geisinger Health System, Danville, PA 17822, USA. Gottesman O; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Ritchie MD; Geisinger Health System, Danville, PA 17822, USA. Shuldiner AR; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Reid JG; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Ledbetter DH; Geisinger Health System, Danville, PA 17822, USA. Baras A; Regeneron Genetics Center, Tarrytown, NY 10591, USA. Carey DJ; Geisinger Health System, Danville, PA 17822, USA. .
Phosphorylation of calcium/calmodulin-stimulated protein kinase II at T286 enhances invasion and migration of human breast cancer cells.
Autorzy:
Chi M; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia.; Priority Research Centre for Cancer, Hunter Medical Research Institute, Faculty of Health, The University of Newcastle, Callaghan, New South Wales, Australia. Evans H; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia. Gilchrist J; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia. Mayhew J; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia. Hoffman A; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia. Pearsall EA; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia.; Priority Research Centre for Cancer, Hunter Medical Research Institute, Faculty of Health, The University of Newcastle, Callaghan, New South Wales, Australia. Jankowski H; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia.; Priority Research Centre for Cancer, Hunter Medical Research Institute, Faculty of Health, The University of Newcastle, Callaghan, New South Wales, Australia. Brzozowski JS; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia.; Priority Research Centre for Cancer, Hunter Medical Research Institute, Faculty of Health, The University of Newcastle, Callaghan, New South Wales, Australia. SkeldingKA; School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales, Australia.; Priority Research Centre for Cancer, Hunter Medical Research Institute, Faculty of Health, The University of Newcastle, Callaghan, New South Wales, Australia.
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Źródło:
Scientific reports [Sci Rep] 2016 Sep 08; Vol. 6, pp. 33132. Date of Electronic Publication: 2016 Sep 08.
Does Preoperative Platelet Function Predict Bleeding in Patients Undergoing Off Pump Coronary Artery Bypass Surgery?
Autorzy:
Berger PB; Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania.; Cardiovascular Center for Clinical Research, Geisinger Medical Center, Danville, Pennsylvania. Kirchner HL; Center for Health Research, Geisinger Medical Center, Danville, Pennsylvania. Wagner ES; Cardiovascular Center for Clinical Research, Geisinger Medical Center, Danville, Pennsylvania. Ismail-Sayed I; General Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania. Yahya S; Siskiyou Pediatrics Clinic, Grants Pass, Oregon. Benoit C; Department of Cardiothoracic Surgery, Geisinger Medical Center, Danville, Pennsylvania. Blankenship JC; Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania. Carter R; Department of Cardiothoracic Surgery, Geisinger Medical Center, Danville, Pennsylvania. Casale AS; Department of Cardiothoracic Surgery, Geisinger Medical Center, Danville, Pennsylvania. Green SM; Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania. Scott TD; Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania. SkeldingKA; Department of Cardiology, Geisinger Medical Center, Danville, Pennsylvania. Woods E; Department of Cardiothoracic Surgery, Geisinger Medical Center, Danville, Pennsylvania. Henry YM; Cardiovascular Center for Clinical Research, Geisinger Medical Center, Danville, Pennsylvania.
Frequency of coronary angiography and revascularization among men and women with myocardial infarction and their relationship to mortality at one year: an analysis of the Geisinger myocardial infarction cohort.
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