Autor: "Smith MD" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.
Autorzy:: Guo Y; Immunology, Janssen Research, Pennsylvania, United States of America.
Walsh AM; Immunology, Janssen Research, Pennsylvania, United States of America.
Canavan M; Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
Wechalekar MD; Rheumatology Unit, Repatriation General Hospital and Flinders University, Adelaide, Australia.
Cole S; Immunology, Janssen Research, Pennsylvania, United States of America.
Yin X; Immunology, Janssen Research, Pennsylvania, United States of America.
Scott B; Immunology, Janssen Research, Pennsylvania, United States of America.
Loza M; Immunology, Janssen Research, Pennsylvania, United States of America.
Orr C; Centre for Arthritis and Rheumatic Diseases, St. Vincent's University Hospital, University College Dublin, Elm Park, Dublin, Ireland.
McGarry T; Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
Bombardieri M; Queen Mary University of London, Charterhouse Square, London, United Kingdom.
Humby F; Queen Mary University of London, Charterhouse Square, London, United Kingdom.
Proudman SM; Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia and Discipline of Medicine, University of Adelaide, Adelaide, Australia.
Pitzalis C; Queen Mary University of London, Charterhouse Square, London, United Kingdom.
Smith MD; Rheumatology Unit, Repatriation General Hospital and Flinders University, Adelaide, Australia.
Friedman JR; Immunology, Janssen Research, Pennsylvania, United States of America.
Anderson I; Immunology, Janssen Research, Pennsylvania, United States of America.
Madakamutil L; Immunology, Janssen Research, Pennsylvania, United States of America.
Veale DJ; Centre for Arthritis and Rheumatic Diseases, St. Vincent's University Hospital, University College Dublin, Elm Park, Dublin, Ireland.
Fearon U; Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
Nagpal S; Immunology, Janssen Research, Pennsylvania, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2018 Feb 28; Vol. 13 (2), pp. e0192704. Date of Electronic Publication: 2018 Feb 28 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Down-Regulation*
Arthritis, Rheumatoid/*pathology
Programmed Cell Death 1 Receptor/*metabolism
Synovial Membrane/*pathology
Disease Progression ; Female ; Humans ; Male ; Synovial Membrane/metabolism

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Skocz do pozycji: 2.

Tytuł:: Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways.
Autorzy:: Walsh AM; Immunology, Janssen Research and Development, LLC., Spring House, Pennsylvania, United States of America.
Wechalekar MD; Repatriation General Hospital, Daw Park, South Australia, Australia.; Flinders University, Adelaide, South Australia, Australia.
Guo Y; Immunology, Janssen Research and Development, LLC., Spring House, Pennsylvania, United States of America.
Yin X; Immunology, Janssen Research and Development, LLC., Spring House, Pennsylvania, United States of America.
Weedon H; Flinders University, Adelaide, South Australia, Australia.
Proudman SM; Rheumatology Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.; Discipline of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Smith MD; Flinders University, Adelaide, South Australia, Australia.
Nagpal S; Immunology, Janssen Research and Development, LLC., Spring House, Pennsylvania, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Sep 01; Vol. 12 (9), pp. e0183928. Date of Electronic Publication: 2017 Sep 01 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Antirheumatic Agents/*therapeutic use
Arthritis, Rheumatoid/*drug therapy
Synovial Membrane/*drug effects
T-Lymphocytes/*cytology
Adult ; Aged ; Arthroscopy ; Biopsy ; Case-Control Studies ; Cell Differentiation ; Down-Regulation ; Drug Therapy, Combination ; Female ; Humans ; Hydroxychloroquine/therapeutic use ; Lymphocyte Activation/drug effects ; Male ; Methotrexate/therapeutic use ; Middle Aged ; Plasma Cells/cytology ; Principal Component Analysis ; Remission Induction ; Sequence Analysis, RNA ; Sulfasalazine/therapeutic use ; Synovial Membrane/metabolism ; T-Lymphocytes/drug effects ; Transcriptome

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Skocz do pozycji: 3.

Tytuł:: Arthroscopic guided synovial biopsy in rheumatology: current perspectives.
Autorzy:: Wechalekar MD; Rheumatology Unit, Repatriation General Hospital, Adelaide, South Australia, Australia.; Flinders University of South Australia, Adelaide, South Australia, Australia.
Smith MD; Flinders University of South Australia, Adelaide, South Australia, Australia.; Pokaż więcej
Źródło:: International journal of rheumatic diseases [Int J Rheum Dis] 2017 Feb; Vol. 20 (2), pp. 141-144. Date of Electronic Publication: 2016 Dec 19.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Arthroscopy*
Rheumatic Diseases/*pathology
Rheumatology/*methods
Synovial Membrane/*pathology
Biopsy ; Humans ; Predictive Value of Tests ; Prognosis ; Rheumatic Diseases/immunology ; Rheumatic Diseases/therapy ; Synovial Membrane/immunology

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