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Tytuł :
MicroRNA-17: A Modulator of Interferon Regulatory Factor 9-Induced Phenotypic Switching in Vascular Smooth Muscle Cells.
Autorzy :
Amiya E; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Therapeutic Strategy for Heart Failure, The University of Tokyo, Tokyo, Japan.
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Źródło :
American journal of hypertension [Am J Hypertens] 2020 Dec 31; Vol. 33 (12), pp. 1078-1080.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
MicroRNAs*/genetics
Muscle, Smooth, Vascular*
Cell Proliferation ; Factor IX ; Interferon-Stimulated Gene Factor 3, gamma Subunit ; Interferons ; Myocytes, Smooth Muscle
Czasopismo naukowe
Tytuł :
PERK Inhibition Promotes Post-angioplasty Re-endothelialization via Modulating SMC Phenotype Changes.
Autorzy :
Wang B; Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Surgery, College of Medicine, The Ohio State University, Columbus, Ohio; Department of Surgery, School of Medicine, University of Virginia, Charlottesville, Virginia.
Zhang M; Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Surgery, College of Medicine, The Ohio State University, Columbus, Ohio; Cellular and Molecular Pathology Graduate Program, Department of Pathology, University of Wisconsin-Madison, Madison, Wisconsin.
Urabe G; Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Surgery, College of Medicine, The Ohio State University, Columbus, Ohio.
Shirasu T; Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Surgery, College of Medicine, The Ohio State University, Columbus, Ohio; Department of Surgery, School of Medicine, University of Virginia, Charlottesville, Virginia; Department of Physiology & Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio.
Guo LW; Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Surgery, College of Medicine, The Ohio State University, Columbus, Ohio; Department of Surgery, School of Medicine, University of Virginia, Charlottesville, Virginia; Department of Physiology & Cell Biology, College of Medicine, The Ohio State University, Columbus, Ohio. Electronic address: .
Kent KC; Department of Surgery, College of Medicine, The Ohio State University, Columbus, Ohio; Department of Surgery, School of Medicine, University of Virginia, Charlottesville, Virginia. Electronic address: .
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Źródło :
The Journal of surgical research [J Surg Res] 2021 Jan; Vol. 257, pp. 294-305. Date of Electronic Publication: 2020 Aug 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Angioplasty, Balloon/*adverse effects
Coronary Restenosis/*prevention & control
Myocytes, Smooth Muscle/*drug effects
Protein Kinase Inhibitors/*administration & dosage
Re-Epithelialization/*drug effects
eIF-2 Kinase/*antagonists & inhibitors
Angioplasty, Balloon/instrumentation ; Animals ; Carotid Arteries/drug effects ; Carotid Arteries/pathology ; Carotid Arteries/surgery ; Coronary Restenosis/etiology ; Disease Models, Animal ; Drug-Eluting Stents/adverse effects ; Endothelial Cells/drug effects ; Endothelial Cells/pathology ; Endothelium, Vascular/cytology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/pathology ; Humans ; Male ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Paracrine Communication/drug effects ; Paracrine Communication/genetics ; RNA, Small Interfering/metabolism ; Rats ; Re-Epithelialization/genetics ; eIF-2 Kinase/genetics
Czasopismo naukowe
Tytuł :
CircSFMBT2 facilitates vascular smooth muscle cell proliferation by targeting miR-331-3p/HDAC5.
Autorzy :
Luo Y; Department of Clinical Medicine, School of Medicine, Nantong University, Nantong 226001, People's Republic of China.
Huang C; Department of Clinical Medicine, School of Medicine, Nantong University, Nantong 226001, People's Republic of China; Department of Vascular Surgery, Affiliated Hospital of Nantong University, Nantong 226001, People's Republic of China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118691. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*physiology
Histone Deacetylases/*metabolism
MicroRNAs/*metabolism
Muscle, Smooth, Vascular/*metabolism
RNA, Circular/*metabolism
Repressor Proteins/*metabolism
Humans ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/metabolism
Czasopismo naukowe
Tytuł :
HDAC5 inhibition reduces angiotensin II-induced vascular contraction, hypertrophy, and oxidative stress in a mouse model.
Autorzy :
Bai L; Heart Research Center of Chonnam National University Hospital, Gwangju 61469, Republic of Korea; Hypertension and Heart Failure, Chonnam National University Hospital, Gwangju 61469, Republic of Korea.
Kee HJ; Heart Research Center of Chonnam National University Hospital, Gwangju 61469, Republic of Korea; Hypertension and Heart Failure, Chonnam National University Hospital, Gwangju 61469, Republic of Korea. Electronic address: .
Choi SY; Heart Research Center of Chonnam National University Hospital, Gwangju 61469, Republic of Korea; Hypertension and Heart Failure, Chonnam National University Hospital, Gwangju 61469, Republic of Korea.
Seok YM; National Development Institute of Korean Medicine, Hwarang-ro, Gyeongsan-si, Gyeongsangbuk-do 38540, Republic of Korea.
Kim GR; Heart Research Center of Chonnam National University Hospital, Gwangju 61469, Republic of Korea; Hypertension and Heart Failure, Chonnam National University Hospital, Gwangju 61469, Republic of Korea.
Kee SJ; Department of Laboratory Medicine, Chonnam National University, Medical School and Hospital, Gwangju 61469, Republic of Korea.
Kook H; Department of Pharmacology, Chonnam National University Medical School, Hwasun, Jeollanam-do 58128, Republic of Korea.
Jeong MH; Heart Research Center of Chonnam National University Hospital, Gwangju 61469, Republic of Korea; Hypertension and Heart Failure, Chonnam National University Hospital, Gwangju 61469, Republic of Korea. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Feb; Vol. 134, pp. 111162. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article
MeSH Terms :
Antihypertensive Agents/*pharmacology
Arterial Pressure/*drug effects
Benzamides/*pharmacology
Histone Deacetylase Inhibitors/*pharmacology
Histone Deacetylases/*metabolism
Hypertension/*prevention & control
Muscle, Smooth, Vascular/*drug effects
Oxadiazoles/*pharmacology
Oxidative Stress/*drug effects
Vascular Remodeling/*drug effects
Vasoconstriction/*drug effects
Angiotensin II ; Animals ; Aorta, Thoracic/drug effects ; Aorta, Thoracic/enzymology ; Aorta, Thoracic/physiopathology ; Cells, Cultured ; Disease Models, Animal ; Histone Deacetylases/deficiency ; Histone Deacetylases/genetics ; Hypertension/chemically induced ; Hypertension/enzymology ; Hypertension/physiopathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/enzymology ; rho-Associated Kinases/genetics ; rho-Associated Kinases/metabolism ; rhoA GTP-Binding Protein/genetics ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
Tytuł :
Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Autorzy :
Zawia A; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Arnold ND; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
West L; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Pickworth JA; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Turton H; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Iremonger J; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Braithwaite AT; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Cañedo J; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Johnston SA; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Thompson AAR; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
Miller G; Department of Oncology and Metabolism (G.M.), University of Sheffield, United Kingdom.; College of Medical and Dental Science, University of Birmingham, United Kingdom (G.M.).
Lawrie A; Department of Infection, Immunity and Cardiovascular Disease (A.Z., N.D.A., L.W., J.A.P., H.T., J.I., A.T.B., J.C., S.A.J., A.A.R.T., A.L.), University of Sheffield, United Kingdom.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jan; Vol. 41 (1), pp. 430-445. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophage Activation*
Vascular Remodeling*
Macrophages, Alveolar/*pathology
Muscle, Smooth, Vascular/*pathology
Pulmonary Arterial Hypertension/*pathology
Adult ; Aged ; Animals ; Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/genetics ; Case-Control Studies ; Cell Proliferation ; Diphtheria Toxin/genetics ; Disease Models, Animal ; Female ; Humans ; Hypoxia/complications ; Macrophages, Alveolar/metabolism ; Male ; Mice, Transgenic ; Middle Aged ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Paracrine Communication ; Peptide Fragments/genetics ; Phenotype ; Pulmonary Arterial Hypertension/etiology ; Pulmonary Arterial Hypertension/metabolism ; Pulmonary Artery/metabolism ; Pulmonary Artery/pathology ; Sex Factors
Czasopismo naukowe
Tytuł :
Obligatory role for PKCδ in PIP 2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells.
Autorzy :
Martín-Aragón Baudel MAS; Department of Pharmacology, University of California, 451, Health Sciences Drive, Suite 3503, Davis, CA, USA.
Shi J; Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK.
Large WA; Vascular Biology Research Centre, Molecular and Clinical Research Institute, St George's, University of London, Cranmer Terrace, London, UK.
Albert AP; Vascular Biology Research Centre, Molecular and Clinical Research Institute, St George's, University of London, Cranmer Terrace, London, UK.
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Źródło :
The Journal of physiology [J Physiol] 2020 Sep; Vol. 598 (18), pp. 3911-3925. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscle, Smooth, Vascular*/metabolism
Transient Receptor Potential Channels*
Animals ; Calcium/metabolism ; Myocytes, Smooth Muscle/metabolism ; Protein Kinase C/metabolism ; Rats ; TRPC Cation Channels
Czasopismo naukowe
Tytuł :
Circ_0020397 regulates the viability of vascular smooth muscle cells by up-regulating GREM1 expression via miR-502-5p in intracranial aneurysm.
Autorzy :
Yin K; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Liu X; Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118800. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Survival/*physiology
Intercellular Signaling Peptides and Proteins/*biosynthesis
Intracranial Aneurysm/*metabolism
MicroRNAs/*biosynthesis
Muscle, Smooth, Vascular/*metabolism
RNA, Circular/*biosynthesis
Gene Expression ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Intracranial Aneurysm/genetics ; MicroRNAs/genetics ; Myocytes, Smooth Muscle/metabolism ; RNA, Circular/genetics ; Up-Regulation/physiology
Czasopismo naukowe
Tytuł :
Berberine inhibits proliferation and apoptosis of vascular smooth muscle cells induced by mechanical stretch via the PDI/ERS and MAPK pathways.
Autorzy :
Wang L; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China.
Deng L; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China.
Lin N; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China.
Shi Y; Division of Vascular Surgery, The First Affiliated Hospital of Sun Yat-sen University, China.
Chen J; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China.
Zhou Y; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China.
Chen D; Experimental Center for Basic Medical Teaching, Zhongshan School of Medicine, Sun Yat-sen University, China.
Liu S; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China. Electronic address: .
Li C; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118253. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Berberine/*pharmacology
Muscle, Smooth, Vascular/*metabolism
Protein Disulfide-Isomerases/*metabolism
Animals ; Apoptosis/drug effects ; Atherosclerosis/metabolism ; Berberine/metabolism ; Cell Proliferation/drug effects ; Cells, Cultured ; China ; Endoplasmic Reticulum Stress/drug effects ; Male ; Mechanical Phenomena ; Mice ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/drug effects ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Oxidation-Reduction/drug effects ; Phosphorylation ; Signal Transduction/drug effects ; Stress, Mechanical ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
[Olmesartan inhibits age-associated migration and invasion of human aortic vascular smooth muscle cells by upregulating miR-3133 axis].
Autorzy :
Zhang Y; Department of Cardiology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
Sheng S; Department of Cardiology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
Liang Q; Department of Cardiology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
Zhang L; Department of Cardiology, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510080, China.
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Źródło :
Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2020 Apr 30; Vol. 40 (4), pp. 499-505.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle, Smooth, Vascular*
MicroRNAs/*genetics
Cell Movement ; Cell Proliferation ; Cells, Cultured ; Humans ; Imidazoles ; Matrix Metalloproteinase 2 ; Myocytes, Smooth Muscle ; Tetrazoles
Czasopismo naukowe
Tytuł :
Statin-mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration.
Autorzy :
Sanyour HJ; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; BioSNTR, Sioux Falls, SD, 57107, USA.
Li N; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; BioSNTR, Sioux Falls, SD, 57107, USA.
Rickel AP; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; BioSNTR, Sioux Falls, SD, 57107, USA.
Torres HM; Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, 57104, USA.; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57007, USA.
Anderson RH; Cellular Therapies and Stem Cell Biology Group, Sanford Research, Sioux Falls, SD, 57104, USA.; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Vermillion, SD, 57069, USA.
Miles MR; BioSNTR, Sioux Falls, SD, 57107, USA.; Mechanical Engineering Department, South Dakota State University, Brookings, SD, 57007, USA.
Childs JD; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; BioSNTR, Sioux Falls, SD, 57107, USA.
Francis KR; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; Cellular Therapies and Stem Cell Biology Group, Sanford Research, Sioux Falls, SD, 57104, USA.; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Vermillion, SD, 57069, USA.
Tao J; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, 57104, USA.; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Vermillion, SD, 57069, USA.; Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57007, USA.
Hong Z; Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SD, 57107, USA.; BioSNTR, Sioux Falls, SD, 57107, USA.
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Źródło :
The Journal of physiology [J Physiol] 2020 Apr; Vol. 598 (8), pp. 1505-1522. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Muscle, Smooth, Vascular*
Animals ; Biomechanical Phenomena ; Cell Movement ; Cells, Cultured ; Cholesterol ; Humans ; Myocytes, Smooth Muscle ; Rats
Czasopismo naukowe
Tytuł :
Upregulation of aurora kinase A promotes vascular smooth muscle cell proliferation and migration by activating the GSK-3β/β-catenin pathway in aortic-dissecting aneurysms.
Autorzy :
Meng J; School of Public Health, North China University of Science and Technology, PR China.
Liu HL; School of Public Health, North China University of Science and Technology, PR China.
Ma D; School of Public Health, North China University of Science and Technology, PR China.
Wang HY; School of Public Health, North China University of Science and Technology, PR China.
Peng Y; School of Public Health, North China University of Science and Technology, PR China.
Wang HL; School of Public Health, North China University of Science and Technology, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Dec 01; Vol. 262, pp. 118491. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Aneurysm, Dissecting/*physiopathology
Aurora Kinase A/*genetics
Glycogen Synthase Kinase 3 beta/*metabolism
Muscle, Smooth, Vascular/*cytology
Adult ; Aged ; Aneurysm, Dissecting/genetics ; Animals ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cells, Cultured ; Down-Regulation ; Female ; Gene Knockdown Techniques ; Humans ; Male ; Mice ; Middle Aged ; Myocytes, Smooth Muscle/metabolism ; Up-Regulation ; Wnt Signaling Pathway/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Autorzy :
Huang J; Department of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205; .
Lam H; Department of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205.
Koziol-White C; Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, NJ 08854.; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
Limjunyawong N; Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Kim D; Center for Personalized Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
Kim N; Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, NJ 08854.
Karmacharya N; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
Rajkumar P; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Firer D; Department of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205.
Dalesio NM; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Jude J; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
Kurten RC; Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205.
Pluznick JL; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Deshpande DA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, PA 19107.
Penn RB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, PA 19107.
Liggett SB; Center for Personalized Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.; Department of Medical Engineering, University of South Florida, Tampa, FL 33612.
Panettieri RA Jr; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
Dong X; Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
An SS; Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, NJ 08854; .; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 10; Vol. 117 (45), pp. 28485-28495. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anoctamin-1/*metabolism
Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism
Muscle, Smooth/*metabolism
Neoplasm Proteins/*metabolism
Receptors, Odorant/*metabolism
Adenylyl Cyclases/metabolism ; Bronchi/metabolism ; Calcium/metabolism ; Cells, Cultured ; Humans ; Lung/metabolism ; Muscle Contraction/physiology ; Muscle Relaxation ; Myocytes, Smooth Muscle/metabolism ; Receptors, Odorant/genetics
Czasopismo naukowe
Tytuł :
Long Noncoding RNA Hypoxia-Inducible Factor-1 Alpha-Antisense RNA 1 Regulates Vascular Smooth Muscle Cells to Promote the Development of Thoracic Aortic Aneurysm by Modulating Apoptotic Protease-Activating Factor 1 and Targeting let-7g.
Autorzy :
Zhang X; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Li H; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Guo X; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Hu J; Department of Neonatal Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Li B; Department of Cardiac Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China. Electronic address: .
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Źródło :
The Journal of surgical research [J Surg Res] 2020 Nov; Vol. 255, pp. 602-611. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Aortic Aneurysm, Thoracic/*genetics
Apoptotic Protease-Activating Factor 1/*genetics
MicroRNAs/*metabolism
Muscle, Smooth, Vascular/*pathology
RNA, Long Noncoding/*metabolism
Aorta, Thoracic/cytology ; Aorta, Thoracic/pathology ; Aortic Aneurysm, Thoracic/pathology ; Apoptosis/drug effects ; Apoptosis/genetics ; Apoptotic Protease-Activating Factor 1/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Computational Biology ; Extracellular Matrix Proteins/genetics ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Male ; MicroRNAs/agonists ; MicroRNAs/antagonists & inhibitors ; Middle Aged ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/pathology
Czasopismo naukowe
Tytuł :
Vitamin D deficiency downregulates TASK-1 channels and induces pulmonary vascular dysfunction.
Autorzy :
Callejo M; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Mondejar-Parreño G; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Morales-Cano D; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Barreira B; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Esquivel-Ruiz S; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Olivencia MA; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Manaud G; Université Paris-Saclay, AP-HP, INSERM UMR_S 999, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.
Perros F; Université Paris-Saclay, AP-HP, INSERM UMR_S 999, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.
Duarte J; Department of Pharmacology, School of Pharmacy, Universidad de Granada, Granada, Spain.; Ciber Enfermedades Cardiovasculares, Madrid, Spain.
Moreno L; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Cogolludo A; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Perez-Vizcaíno F; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.; CIBER Enfermedades Respiratorias, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 Oct 01; Vol. 319 (4), pp. L627-L640. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypertension, Pulmonary/*metabolism
Muscle, Smooth, Vascular/*metabolism
Nerve Tissue Proteins/*metabolism
Potassium Channels, Tandem Pore Domain/*metabolism
Vitamin D Deficiency/*metabolism
Animals ; Humans ; Lung/metabolism ; Lung/physiopathology ; Male ; Membrane Potentials/physiology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/metabolism ; Rats, Wistar ; Vitamin D/metabolism
Czasopismo naukowe
Tytuł :
[Role of platelet-derived growth factor receptor α positive cells in purinergic inhibitory nerve-smooth muscle transmission].
Autorzy :
Huang X; Department of Anatomy and Physiology, Shanghai Jiao Tong University College of Basic Medicine, Shanghai 200240, China.
Lu HL; Department of Anatomy and Physiology, Shanghai Jiao Tong University College of Basic Medicine, Shanghai 200240, China.
Xu WX; Department of Anatomy and Physiology, Shanghai Jiao Tong University College of Basic Medicine, Shanghai 200240, China. .
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Źródło :
Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2020 Jun 25; Vol. 72 (3), pp. 391-398.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Interstitial Cells of Cajal*
Muscle, Smooth*
Myocytes, Smooth Muscle ; Receptor, Platelet-Derived Growth Factor alpha ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
LncRNA HCG11 regulates proliferation and apoptosis of vascular smooth muscle cell through targeting miR-144-3p/FOXF1 axis in atherosclerosis.
Autorzy :
Liu Y; Department of Clinical laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.
Cui X; Department of Clinical Laboratory, Weapon Industry 206 Hospital, Xi'an, Shaanxi, 710061, China.
Wang C; Department of Clinical laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.
Zhao S; Laboratory Animal Center, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi, 710061, China. .
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Źródło :
Biological research [Biol Res] 2020 Oct 02; Vol. 53 (1), pp. 44. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Atherosclerosis*/genetics
Forkhead Transcription Factors/*genetics
MicroRNAs/*genetics
Myocytes, Smooth Muscle/*cytology
RNA, Long Noncoding/*genetics
Apoptosis/genetics ; Cell Proliferation/genetics ; Humans ; Muscle, Smooth, Vascular/cytology
Czasopismo naukowe
Tytuł :
Protective effects of dioscin on vascular remodeling in pulmonary arterial hypertension via adjusting GRB2/ERK/PI3K-AKT signal.
Autorzy :
Yang Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Yin L; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Zhu M; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Song S; College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China.
Sun C; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Han X; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Xu Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Zhao Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Qi Y; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China.
Xu L; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China; Key Laboratory of Ethnomedicine (Minzu University of China), Ministry of Education, Beijing 100081, China. Electronic address: .
Peng JY; College of Pharmacy, Dalian Medical University, Western 9 Lvshunnan Road, Dalian 116044, China; Key Laboratory for Basic and Applied Research on Pharmacodynamic Substances of Traditional Chinese Medicine of Liaoning Province, Dalian Medical University, Dalian 116044, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 111056. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Diosgenin/*analogs & derivatives
Extracellular Signal-Regulated MAP Kinases/*metabolism
GRB2 Adaptor Protein/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Phosphatidylinositol 3-Kinase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Pulmonary Arterial Hypertension/*drug therapy
Vascular Remodeling/*drug effects
Animals ; Apoptosis/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Diosgenin/pharmacology ; Disease Models, Animal ; GRB2 Adaptor Protein/genetics ; Male ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Pulmonary Arterial Hypertension/enzymology ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Artery/drug effects ; Pulmonary Artery/enzymology ; Pulmonary Artery/pathology ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
PDGF/MEK/ERK axis represses Ca pump PMCA4 in pulmonary arterial smooth muscle cells.
Autorzy :
Deng L; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Chen J; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Wang T; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Chen B; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Yang L; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Liao J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Chen Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Wang J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Tang H; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Yi J; Instrumental Analysis Center of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Kang K; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.; Department of Biochemistry and Molecular Biology, Carson International Cancer Center, Shenzhen University Health Sciences Center, Shenzhen, Guangdong, People's Republic of China.
Li L; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Gou D; Shenzhen Key Laboratory of Microbial Genetic Engineering, Vascular Disease Research Center, College of Life Sciences and Oceanography, Guangdong Provincial Key Laboratory of Regional Immunity and Disease, Carson International Cancer Center, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 Jan 01; Vol. 320 (1), pp. C66-C79. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Becaplermin/*pharmacology
Calcium/*metabolism
Extracellular Signal-Regulated MAP Kinases/*metabolism
Mitogen-Activated Protein Kinase Kinases/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Plasma Membrane Calcium-Transporting ATPases/*metabolism
Animals ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Disease Models, Animal ; Down-Regulation ; Male ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Pulmonary Arterial Hypertension/enzymology ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Artery/drug effects ; Pulmonary Artery/enzymology ; Rats, Sprague-Dawley ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
The dynamic change of phenotypic markers of smooth muscle cells in an animal model of cerebral small vessel disease.
Autorzy :
Liu N; Department of Neurology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai 200040, China.
Xue Y; Department of Neurology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai 200040, China.
Tang J; Department of Neurology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai 200040, China.
Zhang M; Department of Neurology, North Huashan hospital, Fudan University, No.108 Lu Xiang Road, Shanghai 201900, China.
Ren X; Department of Neurology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai 200040, China.
Fu J; Department of Neurology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai 200040, China; Department of Neurology, North Huashan hospital, Fudan University, No.108 Lu Xiang Road, Shanghai 201900, China. Electronic address: .
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Źródło :
Microvascular research [Microvasc Res] 2021 Jan; Vol. 133, pp. 104061. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Small Vessel Diseases/*etiology
Extracellular Matrix/*metabolism
Hypertension/*complications
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Age Factors ; Animals ; Biomarkers/metabolism ; Cells, Cultured ; Cerebral Arteries/metabolism ; Cerebral Arteries/pathology ; Cerebral Arteries/physiopathology ; Cerebral Small Vessel Diseases/metabolism ; Cerebral Small Vessel Diseases/pathology ; Cerebral Small Vessel Diseases/physiopathology ; Disease Models, Animal ; Extracellular Matrix/pathology ; Fibronectins/metabolism ; Hypertension/metabolism ; Hypertension/physiopathology ; Laminin/metabolism ; Male ; Muscle, Smooth, Vascular/pathology ; Muscle, Smooth, Vascular/physiopathology ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Rats, Inbred SHR ; Rats, Inbred WKY ; Vascular Remodeling ; Vasoconstriction
Czasopismo naukowe
Tytuł :
Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response.
Autorzy :
Chattopadhyay A; Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX (A.C., C.S.K., K.K., A.K., J.C., D.M.M.).
Kwartler CS; Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX (A.C., C.S.K., K.K., A.K., J.C., D.M.M.).
Kaw K; Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX (A.C., C.S.K., K.K., A.K., J.C., D.M.M.).
Li Y; Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, TX (.L., S.A.L., Y.H.S.).
Kaw A; Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX (A.C., C.S.K., K.K., A.K., J.C., D.M.M.).
Chen J; Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX (A.C., C.S.K., K.K., A.K., J.C., D.M.M.).
LeMaire SA; Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, TX (.L., S.A.L., Y.H.S.).
Shen YH; Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, TX (.L., S.A.L., Y.H.S.).
Milewicz DM; Division of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX (A.C., C.S.K., K.K., A.K., J.C., D.M.M.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jan; Vol. 41 (1), pp. 302-316. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transdifferentiation/*drug effects
Cholesterol/*toxicity
Fibroblasts/*drug effects
Macrophages/*drug effects
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Unfolded Protein Response/*drug effects
Activating Transcription Factor 4/metabolism ; Animals ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cell Line ; Endoplasmic Reticulum Stress/drug effects ; Eukaryotic Initiation Factor-2/metabolism ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Kruppel-Like Transcription Factors/metabolism ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Plaque, Atherosclerotic ; eIF-2 Kinase/metabolism
Czasopismo naukowe

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