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Wyszukujesz frazę ""Sobolevsky AI"" wg kryterium: Autor


Wyświetlanie 1-18 z 18
Tytuł:
Structural basis of AMPA receptor inhibition by trans-4-butylcyclohexane carboxylic acid.
Autorzy:
Yelshanskaya MV; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Singh AK; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.
Narangoda C; Chemistry Department, Carnegie Mellon University, Pittsburgh, PA, USA.
Williams RSB; Centre for Biomedical Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, UK.
Kurnikova MG; Chemistry Department, Carnegie Mellon University, Pittsburgh, PA, USA.
Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2022 Jul; Vol. 179 (14), pp. 3628-3644. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carboxylic Acids*
Receptors, AMPA*/metabolism
Cyclohexanes ; Humans ; Seizures
Czasopismo naukowe
Tytuł:
Cytoplasmic Inter-Subunit Interface Controls Use-Dependence of Thermal Activation of TRPV3 Channel.
Autorzy:
Macikova L; Department of Cellular Neurophysiology, Institute of Physiology Czech Academy of Sciences, 142 20 Prague, Czech Republic.; Department of Physiology, Faculty of Science, Charles University, 128 00 Prague, Czech Republic.
Vyklicka L; Department of Cellular Neurophysiology, Institute of Physiology Czech Academy of Sciences, 142 20 Prague, Czech Republic.
Barvik I; Division of Biomolecular Physics, Institute of Physics, Faculty of Mathematics and Physics, Charles University, 121 16 Prague, Czech Republic.
Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
Vlachova V; Department of Cellular Neurophysiology, Institute of Physiology Czech Academy of Sciences, 142 20 Prague, Czech Republic. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Aug 16; Vol. 20 (16). Date of Electronic Publication: 2019 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cytoplasm/*metabolism
TRPV Cation Channels/*metabolism
HEK293 Cells ; Hot Temperature ; Humans ; Molecular Dynamics Simulation ; Mutation ; Protein Domains ; Protein Subunits/chemistry ; Protein Subunits/genetics ; Protein Subunits/metabolism ; TRPV Cation Channels/chemistry ; TRPV Cation Channels/genetics
Czasopismo naukowe
Tytuł:
Proton-independent activation of acid-sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis.
Autorzy:
Osmakov DI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.
Koshelev SG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Andreev YA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.
Dubinnyi MA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Kublitski VS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Efremov RG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Kozlov SA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2018 Mar; Vol. 175 (6), pp. 924-937. Date of Electronic Publication: 2018 Feb 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Acid Sensing Ion Channels/*drug effects
Alkaloids/*pharmacology
Laurus/*chemistry
Acid Sensing Ion Channels/metabolism ; Alkaloids/chemistry ; Alkaloids/isolation & purification ; Allosteric Regulation/drug effects ; Animals ; Female ; Humans ; Hydrogen-Ion Concentration ; Oocytes ; Patch-Clamp Techniques ; Plant Leaves ; Protons ; Rats ; Species Specificity ; Xenopus laevis
Czasopismo naukowe
Tytuł:
Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Autorzy:
Twomey EC; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA. Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, 650 West 168th Street, New York, NY 10032, USA.
Yelshanskaya MV; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA.
Grassucci RA; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA. Howard Hughes Medical Institute, 650 West 168th Street, New York, NY 10032, USA.
Frank J; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA. Department of Biological Sciences, Columbia University, 650 West 168th Street, New York, NY 10032, USA. Howard Hughes Medical Institute, 650 West 168th Street, New York, NY 10032, USA. .
Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA. .
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Źródło:
Science (New York, N.Y.) [Science] 2016 Jul 01; Vol. 353 (6294), pp. 83-6.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Synaptic Transmission*
Brain/*metabolism
Calcium Channels/*chemistry
Receptors, AMPA/*chemistry
Animals ; Calcium Channels/ultrastructure ; Cryoelectron Microscopy ; HEK293 Cells ; Humans ; Models, Molecular ; Protein Stability ; Protein Structure, Secondary ; Rats ; Receptors, AMPA/ultrastructure
Czasopismo naukowe
Tytuł:
Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors.
Autorzy:
Yelshanskaya MV; Department of Biochemistry and Molecular Biophysics, Columbia University 650 West 168th Street, New York, NY 10032.
Saotome K; Department of Biochemistry and Molecular Biophysics, Columbia University 650 West 168th Street, New York, NY 10032.
Singh AK; Department of Biochemistry and Molecular Biophysics, Columbia University 650 West 168th Street, New York, NY 10032.
Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University 650 West 168th Street, New York, NY 10032.
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Źródło:
Scientific reports [Sci Rep] 2016 Jan 07; Vol. 6, pp. 19082. Date of Electronic Publication: 2016 Jan 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Interaction Domains and Motifs*
Protein Subunits/*chemistry
Protein Subunits/*metabolism
Receptors, AMPA/*chemistry
Receptors, AMPA/*metabolism
Amino Acid Substitution ; Cell Line ; Gene Knockout Techniques ; Humans ; Ion Channel Gating ; Models, Molecular ; Mutation ; Protein Conformation ; Protein Multimerization ; Receptors, AMPA/genetics
Czasopismo naukowe
Tytuł:
Structure of an agonist-bound ionotropic glutamate receptor.
Autorzy:
Yelshanskaya MV; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA.
Li M; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA.
Sobolevsky AI; Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA. .
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Źródło:
Science (New York, N.Y.) [Science] 2014 Aug 29; Vol. 345 (6200), pp. 1070-4. Date of Electronic Publication: 2014 Aug 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Ion Channel Gating*
Pyrimidinones/*pharmacology
Receptors, AMPA/*agonists
Receptors, AMPA/*chemistry
Animals ; Cross-Linking Reagents/chemistry ; Crystallography, X-Ray ; Cysteine/chemistry ; Glutamic Acid/pharmacology ; HEK293 Cells ; Humans ; Models, Chemical ; Organophosphonates/chemistry ; Organophosphonates/pharmacology ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Quinoxalines/chemistry ; Quinoxalines/pharmacology ; Rats ; Receptors, AMPA/genetics
Czasopismo naukowe
Tytuł:
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor.
Autorzy:
Sobolevsky AI; Vollum Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA.
Rosconi MP
Gouaux E
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Źródło:
Nature [Nature] 2009 Dec 10; Vol. 462 (7274), pp. 745-56.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, AMPA/*chemistry
Receptors, AMPA/*metabolism
Animals ; Cell Line ; Crystallization ; Crystallography, X-Ray ; Ion Channel Gating ; Models, Molecular ; Potassium Channels/chemistry ; Potassium Channels/metabolism ; Protein Conformation ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Rats ; Receptors, AMPA/antagonists & inhibitors ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/metabolism
Czasopismo naukowe
    Wyświetlanie 1-18 z 18

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