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    Tytuł:
    In vivo phenotyping of the microvasculature in necrotizing enterocolitis with multicontrast optical imaging.
    Autorzy:
    Senarathna J; Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    Kovler M; Department of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    Prasad A; Department of Biophysics, The Johns Hopkins University, Baltimore, Maryland, USA.
    Bhargava A; Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    Thakor NV; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland, USA.
    Sodhi CP; Department of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    Hackam DJ; Department of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    Pathak AP; Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland, USA.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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    Źródło:
    Microcirculation (New York, N.Y. : 1994) [Microcirculation] 2022 Oct; Vol. 29 (6-7), pp. e12768. Date of Electronic Publication: 2022 Jun 01.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Enterocolitis, Necrotizing*/diagnostic imaging
    Enterocolitis, Necrotizing*/etiology
    Enterocolitis, Necrotizing*/pathology
    Humans ; Infant, Newborn ; Animals ; Microvessels ; Microcirculation/physiology ; Infant, Premature ; Optical Imaging/adverse effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The role of in utero endotoxin exposure in the development of inflammatory bowel disease in mice.
    Autorzy:
    Banfield E; Department of Human Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Fulton W; Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Burd I; Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Kovler ML; Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Sodhi CP; Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Hackam DJ; Department of Human Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
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    Źródło:
    American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2020 Oct; Vol. 84 (4), pp. e13302. Date of Electronic Publication: 2020 Aug 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Colitis, Ulcerative/*immunology
    Inflammatory Bowel Diseases/*immunology
    Lipopolysaccharides/*metabolism
    Uterus/*metabolism
    Animals ; Dextran Sulfate ; Disease Models, Animal ; Disease Resistance ; Female ; Gastrointestinal Microbiome ; Humans ; Immunity, Cellular ; Mice ; Mice, Inbred C57BL ; Pregnancy ; Prenatal Exposure Delayed Effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis.
    Autorzy:
    Haileselassie B; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Department of Pediatrics, Division of Critical Care, Stanford University School of Medicine, 770 Welch Road, Suite 435, Palo Alto, CA, 94304-5731, USA. .
    Su E; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Pozios I; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Niño DF; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Liu H; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Lu DY; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Ventoulis I; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Fulton WB; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Sodhi CP; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Hackam D; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    O'Rourke B; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Abraham T; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
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    Źródło:
    Intensive care medicine experimental [Intensive Care Med Exp] 2017 Dec; Vol. 5 (1), pp. 21. Date of Electronic Publication: 2017 Apr 12.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mucosa-associated bacterial diversity in necrotizing enterocolitis.
    Autorzy:
    Brower-Sinning R; Division of Pediatric Surgery, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Zhong D; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Good M; Division of Newborn Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Firek B; Division of Pediatric Surgery, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Baker R; Division of Newborn Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Sodhi CP; Division of Pediatric Surgery, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Hackam DJ; Division of Pediatric Surgery, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Morowitz MJ; Division of Pediatric Surgery, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 Sep 09; Vol. 9 (9), pp. e105046. Date of Electronic Publication: 2014 Sep 09 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Biodiversity*
    Bacteria/*isolation & purification
    Enterocolitis, Necrotizing/*microbiology
    Intestinal Mucosa/*microbiology
    Bacteria/genetics ; DNA, Bacterial/genetics ; Humans ; Infant ; Infant, Newborn ; Sequence Analysis, DNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors.
    Autorzy:
    Neal MD; Division of Pediatric Surgery Children's Hospital of Pittsburgh and Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
    Jia H
    Eyer B
    Good M
    Guerriero CJ
    Sodhi CP
    Afrazi A
    Prindle T Jr
    Ma C
    Branca M
    Ozolek J
    Brodsky JL
    Wipf P
    Hackam DJ
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    Źródło:
    PloS one [PLoS One] 2013 Jun 12; Vol. 8 (6), pp. e65779. Date of Electronic Publication: 2013 Jun 12 (Print Publication: 2013).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study
    MeSH Terms:
    Small Molecule Libraries*
    Acetylglucosamine/*analogs & derivatives
    Drug Discovery/*methods
    Inflammation/*drug therapy
    Toll-Like Receptor 4/*antagonists & inhibitors
    Acetylglucosamine/chemical synthesis ; Acetylglucosamine/chemistry ; Acetylglucosamine/pharmacology ; Analysis of Variance ; Animals ; Binding Sites/genetics ; DNA Primers/genetics ; Enterocolitis, Necrotizing/drug therapy ; Enterocytes/metabolism ; Humans ; Lipid A/analogs & derivatives ; Lipid A/metabolism ; Macrophages/metabolism ; Mice ; Protein Binding ; Real-Time Polymerase Chain Reaction ; Tritium
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Innate immune signaling in the pathogenesis of necrotizing enterocolitis.
    Autorzy:
    Hackam DJ; Division of Pediatric Surgery, Department of Surgery, Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine, One Children's Hospital Drive, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. />Afrazi A
    Good M
    Sodhi CP
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    Źródło:
    Clinical & developmental immunology [Clin Dev Immunol] 2013; Vol. 2013, pp. 475415. Date of Electronic Publication: 2013 May 23.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Review
    MeSH Terms:
    Enterocolitis, Necrotizing/*immunology
    Enterocytes/*immunology
    Infant, Premature, Diseases/*immunology
    Intestinal Mucosa/*immunology
    Signal Transduction/*immunology
    Toll-Like Receptor 4/*immunology
    Amniotic Fluid/immunology ; Apoptosis ; Enterocolitis, Necrotizing/pathology ; Enterocytes/pathology ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/immunology ; Humans ; Immunity, Innate ; Infant ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases/pathology ; Intestinal Mucosa/pathology ; Lipopolysaccharides/immunology ; Toll-Like Receptor 4/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis.
    Autorzy:
    Yi H; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
    Patel AK
    Sodhi CP
    Hackam DJ
    Hackam AS
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    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (5), pp. e36560. Date of Electronic Publication: 2012 May 17.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis/*physiology
    Photoreceptor Cells, Vertebrate/*physiology
    Signal Transduction/*physiology
    Toll-Like Receptor 4/*physiology
    Wnt Proteins/*metabolism
    Animals ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Generation of mice harbouring a conditional loss-of-function allele of Gata6.
    Autorzy:
    Sodhi CP; Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA. />Li J
    Duncan SA
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    Źródło:
    BMC developmental biology [BMC Dev Biol] 2006 Apr 12; Vol. 6, pp. 19. Date of Electronic Publication: 2006 Apr 12.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    GATA6 Transcription Factor/*genetics
    Mice/*genetics
    Alleles ; Animals ; GATA6 Transcription Factor/physiology ; Gene Targeting ; Genes, Lethal ; Integrases/genetics ; Integrases/metabolism ; Intestinal Mucosa/metabolism ; Microfilament Proteins/genetics ; Recombination, Genetic ; Viral Proteins/genetics ; Viral Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-10 z 10

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