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Wyszukujesz frazę ""Sodium–calcium exchanger"" wg kryterium: Temat


Tytuł:
T-type voltage-gated channels, Na -exchanger, and calpain-2 promote photoreceptor cell death in inherited retinal degeneration.
Autorzy:
Yan J; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.; Cell Death Mechanism Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, 72076, Germany.
Wang L; Cell Death Mechanism Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, 72076, Germany.
Yang QL; The Third Affiliated Hospital of Kunming Medical University &Yunnan Cancer Hospital, Kunming, Yunnan, 650118, China.
Yang QX; The Third Affiliated Hospital of Kunming Medical University &Yunnan Cancer Hospital, Kunming, Yunnan, 650118, China.
He X; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, 72076, Germany.; High-resolution Functional Imaging and Test Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.
Dong Y; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.
Hu Z; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.
Seeliger MW; Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.
Jiao K; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.
Paquet-Durand F; Cell Death Mechanism Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 01; Vol. 22 (1), pp. 92. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinal Degeneration*/metabolism
Sirtuins*/metabolism
Egtazic Acid/*analogs & derivatives
Mice ; Animals ; Calpain/metabolism ; Sodium-Calcium Exchanger ; Photoreceptor Cells/metabolism ; Photoreceptor Cells/pathology ; Cell Death
Czasopismo naukowe
Tytuł:
Inhibition of Acid-Sensing Ion Channels by KB-R7943, a Reverse Na Exchanger Inhibitor.
Autorzy:
Sun HW; Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Chu XP; Department of Biomedical Sciences, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.
Simon RP; Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Xiong ZG; Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Leng TD; Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA.
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Źródło:
Biomolecules [Biomolecules] 2023 Mar 10; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Acid Sensing Ion Channels*
Sodium-Calcium Exchanger*/genetics
Cricetinae ; Mice ; Animals ; Cricetulus ; CHO Cells
Czasopismo naukowe
Tytuł:
Regulation of K -Exchangers (NCKX).
Autorzy:
Al-Khannaq M; Department of Biochemistry & Molecular Biology, Libin Cardiovascular Institute and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Lytton J; Department of Biochemistry & Molecular Biology, Libin Cardiovascular Institute and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 29; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Calcium*/metabolism
Sodium-Calcium Exchanger*/genetics
Sodium-Calcium Exchanger*/metabolism
Czasopismo naukowe
Tytuł:
Structure-Based Function and Regulation of NCX Variants: Updates and Challenges.
Autorzy:
Khananshvili D; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Medical School, Tel-Aviv University, Tel-Aviv 69978, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 21; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Eukaryotic Cells*/metabolism
Sodium-Calcium Exchanger*/genetics
Sodium-Calcium Exchanger*/metabolism
Animals ; Humans ; Scattering, Small Angle ; X-Ray Diffraction ; Protein Isoforms/metabolism ; Ion Transport/physiology ; Calcium/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of Voltage-Gated Na Exchanging Process.
Autorzy:
Wu SN; Department of Physiology, National Cheng Kung University Medical College, Tainan 70101, Taiwan.; Institute of Basic Medical Sciences, National Cheng Kung University Medical College, Tainan 70101, Taiwan.; Department of Post-Baccalaureate Medicine, National Sun Yat-sen University Medical College, Kaohsiung 80708, Taiwan.
Yu MC; Department of Physiology, National Cheng Kung University Medical College, Tainan 70101, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 16; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
Thiourea*/pharmacology
Sodium-Calcium Exchanger*
Czasopismo naukowe
Tytuł:
The reverse mode of the Na exchanger contributes to the pacemaker mechanism in rabbit sinus node cells.
Autorzy:
Tóth N; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 12, P.O. Box 427, Szeged, 6720, Hungary.
Loewe A; Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Szlovák J; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 12, P.O. Box 427, Szeged, 6720, Hungary.
Kohajda Z; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary.
Bitay G; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 12, P.O. Box 427, Szeged, 6720, Hungary.
Levijoki J; Orion Pharma, Espoo, Finland.
Papp JG; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 12, P.O. Box 427, Szeged, 6720, Hungary.; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary.
Varró A; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 12, P.O. Box 427, Szeged, 6720, Hungary.; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary.
Nagy N; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 12, P.O. Box 427, Szeged, 6720, Hungary. .; ELKH-SZTE Research Group of Cardiovascular Pharmacology, Szeged, Hungary. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 17; Vol. 12 (1), pp. 21830. Date of Electronic Publication: 2022 Dec 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sodium-Calcium Exchanger*
Sinoatrial Node*/metabolism
Animals ; Rabbits ; Sodium Chloride ; Myocytes, Cardiac/metabolism ; Calcium/metabolism
Czasopismo naukowe
Tytuł:
Antiarrhythmic and Inotropic Effects of Selective Na Exchanger Inhibition: What Can We Learn from the Pharmacological Studies?
Autorzy:
Nagy N; ELKH-SZTE Research Group of Cardiovascular Pharmacology, 6720 Szeged, Hungary.; Department of Pharmacology and Pharmacotherapy, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.
Tóth N; ELKH-SZTE Research Group of Cardiovascular Pharmacology, 6720 Szeged, Hungary.
Nánási PP; Department of Physiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; Department of Dental Physiology and Pharmacology, Faculty of Dentistry, University of Debrecen, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 24; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Sodium-Calcium Exchanger*/metabolism
Anti-Arrhythmia Agents*/pharmacology
Humans ; Ion Channels/metabolism ; Arrhythmias, Cardiac/drug therapy ; Biological Transport/physiology ; Calcium/metabolism
Czasopismo naukowe
Tytuł:
Real time monitoring of cold Ca dependent transcription and its modulation by NCX inhibitors.
Autorzy:
Wang HT; Institute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.; Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.; Department of Biological Science, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Miyairi S; Institute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.; Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Kitamura M; Institute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.; Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Iizuka K; Institute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.; Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Asano Y; Department of Biological Science, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Yoshimura T; Institute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.; Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Kon N; Institute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. .; Laboratory of Animal Integrative Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. .; Suntory Rising Stars Encouragement Program in Life Sciences (SunRiSE), 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto, 619-0284, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 15; Vol. 12 (1), pp. 17325. Date of Electronic Publication: 2022 Oct 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium*/metabolism
Sodium-Calcium Exchanger*/genetics
Sodium-Calcium Exchanger*/metabolism
Animals ; Mammals/metabolism ; Rats
Czasopismo naukowe
Tytuł:
Sodium-Calcium Exchanger 2: A Pivotal Role in Oxaliplatin Induced Peripheral Neurotoxicity and Axonal Damage?
Autorzy:
Ballarini E; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Malacrida A; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Rodriguez-Menendez V; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Pozzi E; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Canta A; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Chiorazzi A; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Monza L; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Semperboni S; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Meregalli C; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Carozzi VA; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Hashemi M; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Nicolini G; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Scuteri A; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Housley SN; Integrated Cancer Research Center, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Cavaletti G; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
Alberti P; School of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, Italy.; NeuroMI (Milan Center for Neuroscience), 20126 Milan, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 02; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Neurotoxicity Syndromes*/etiology
Neurotoxicity Syndromes*/metabolism
Sodium-Calcium Exchanger*/metabolism
Animals ; Axons/metabolism ; Mice ; Oxaliplatin/adverse effects ; Pilot Projects ; Rats
Czasopismo naukowe
Tytuł:
Spatial and Functional Crosstalk between the Mitochondrial Na Pump SERCA in Cardiomyocytes.
Autorzy:
Takeuchi A; Department of Integrative and Systems Physiology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Life Science Innovation Center, University of Fukui, Fukui 910-1193, Japan.
Matsuoka S; Department of Integrative and Systems Physiology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Life Science Innovation Center, University of Fukui, Fukui 910-1193, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 19; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Sarcoplasmic Reticulum*/metabolism
Sodium-Calcium Exchanger*/metabolism
Calcium/metabolism ; HEK293 Cells ; Humans ; Mitochondria/metabolism ; Myocytes, Cardiac/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism
Czasopismo naukowe
Tytuł:
Safranal Induces Vasorelaxation by Inhibiting Ca Exchanger in Isolated Rat Aortic Rings.
Autorzy:
Al-Saigh NN; Department of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman 19328, Jordan.
Abdalla S; Department of Biological Sciences, School of Science, The University of Jordan, Amman 11942, Jordan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 30; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Sodium-Calcium Exchanger*/pharmacology
Vasodilation*
Adenosine Triphosphatases ; Animals ; Aorta, Thoracic ; Calcium/metabolism ; Calcium Chloride/pharmacology ; Cyclohexenes ; Endothelium, Vascular/metabolism ; Indomethacin/pharmacology ; Methylene Blue/pharmacology ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide/metabolism ; Ouabain/pharmacology ; Phenylephrine/pharmacology ; Quinacrine/pharmacology ; Rats ; Rats, Sprague-Dawley ; Terpenes ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł:
Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer.
Autorzy:
Bian Q; Department of Clinical Laboratory, Guangyuan Central Hospital, Guangyuan 628000, China.
Li H; Department of Clinical Laboratory, Guangyuan Central Hospital, Guangyuan 628000, China.
Wang X; Department of Medical Imaging, Guangyuan Central Hospital, Guangyuan 628000, China.
Liang T; Department of Hospital-Acquired Infection Control, Guangyuan Central Hospital, Guangyuan 628000, China.
Zhang K; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China.
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Źródło:
Journal of diabetes research [J Diabetes Res] 2022 May 13; Vol. 2022, pp. 4629419. Date of Electronic Publication: 2022 May 13 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/genetics
Neoplasms*/genetics
Sodium-Calcium Exchanger*/genetics
Antigens, Neoplasm ; Calcium-Binding Proteins ; Carrier Proteins ; Cell Cycle Proteins ; Computational Biology/methods ; Exosome Multienzyme Ribonuclease Complex ; Gene Ontology ; Humans ; Nuclear Proteins ; Prognosis ; RNA-Binding Proteins
Czasopismo naukowe
Tytuł:
Role of Na Exchanger (NCX) in Glioblastoma Cell Migration (In Vitro).
Autorzy:
Brandalise F; Department of Biosciences, University of Milan, 20133 Milano, Italy.
Ramieri M; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Pastorelli E; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Priori EC; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Ratto D; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Venuti MT; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Roda E; Laboratory of Clinical & Experimental Toxicology, Pavia Poison Centre, National Toxicology Information Centre, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS Pavia, 27100 Pavia, Italy.
Talpo F; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
Rossi P; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100 Pavia, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 11; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*
Humans ; Sodium-Calcium Exchanger ; Endothelial Cells ; Cell Movement ; Brain
Czasopismo naukowe
Tytuł:
Impact of a SLC24A5 variant on the retinal pigment epithelium of a Japanese patient with oculocutaneous albinism type 6.
Autorzy:
Saito T; Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Okamura K; Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Kosaki R; Division of Medical Genetics, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Wakamatsu K; Institute for Melanin Chemistry, Fujita Health University, Toyoake, Japan.
Ito S; Institute for Melanin Chemistry, Fujita Health University, Toyoake, Japan.
Nakajima O; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Yamagata, Japan.
Yamashita H; Department of Ophthalmology, Yssamagata University Faculty of Medicine, Yamagata, Japan.
Hozumi Y; Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Suzuki T; Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.
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Źródło:
Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2022 Mar; Vol. 35 (2), pp. 212-219. Date of Electronic Publication: 2021 Dec 27.
Typ publikacji:
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Albinism, Oculocutaneous*/genetics
Hypopigmentation*/genetics
Retinal Pigment Epithelium*/metabolism
Sodium-Calcium Exchanger*/metabolism
Animals ; Humans ; Japan ; Mice
Czasopismo naukowe
Tytuł:
Sodium-calcium exchanger isoform-3 targeted Withania somnifera (L.) Dunal therapeutic intervention ameliorates cognition in the 5xFAD mouse model of Alzheimer's disease.
Autorzy:
Afewerky HK; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .; Department of Pathology and Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .; School of Allied Health Professions, Asmara College of Health Sciences, Asmara, Eritrea. .; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China. .
Li H; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang T; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li X; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Mahaman YAR; Department of Pathology and Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.
Duan L; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qin P; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zheng J; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Pei L; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China.
Lu Y; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China. .; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 27; Vol. 12 (1), pp. 1537. Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sodium-Calcium Exchanger*
Czasopismo naukowe
Tytuł:
Na -related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-L-alanine.
Autorzy:
Petrozziello T; Division of Pharmacology, Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, 'Federico II' University of Naples, Via S. Pansini 5, 80131, Naples, Italy.
Boscia F; Division of Pharmacology, Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, 'Federico II' University of Naples, Via S. Pansini 5, 80131, Naples, Italy.
Tedeschi V; Division of Pharmacology, Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, 'Federico II' University of Naples, Via S. Pansini 5, 80131, Naples, Italy.
Pannaccione A; Division of Pharmacology, Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, 'Federico II' University of Naples, Via S. Pansini 5, 80131, Naples, Italy.
de Rosa V; Division of Pharmacology, Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, 'Federico II' University of Naples, Via S. Pansini 5, 80131, Naples, Italy.
Corvino A; Department of Pharmacy, School of Medicine, 'Federico II' University of Naples, Via D. Montesano 49, 80131, Naples, Italy.
Severino B; Department of Pharmacy, School of Medicine, 'Federico II' University of Naples, Via D. Montesano 49, 80131, Naples, Italy.
Annunziato L; IRCCS SDN, Via E. Gianturco 113, 80143, Naples, Italy.
Secondo A; Division of Pharmacology, Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, 'Federico II' University of Naples, Via S. Pansini 5, 80131, Naples, Italy. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2022 Jan 12; Vol. 20 (1), pp. 8. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:
Calcium*/metabolism
Sodium-Calcium Exchanger*/metabolism
Amino Acids, Diamino ; Animals ; Cyanobacteria Toxins ; Motor Neurons/metabolism ; Protein Isoforms/metabolism ; Rats ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/metabolism
Czasopismo naukowe
Tytuł:
The downregulation of NCXs is positively correlated with the prognosis of stage II-IV colon cancer.
Autorzy:
Xia Z; Colorectal Tumor Surgery Ward, Department of General Surgery, Shengjing Hospital of China Medical University, No. 36, San Hao Street, Shenyang, Liaoning, People's Republic of China.
Wang C; The People's Procuratorate of Liaoning Province Judicial Authentication Center, No. 46, Cong San East Road, Shenyang, Liaoning, 110032, People's Republic of China.; Collaborative Laboratory of Intelligentized Forensic Science (CLIFS), No. 46, Cong San East Road, Shenyang, Liaoning, 110032, People's Republic of China.
Zhang H; Colorectal Tumor Surgery Ward, Department of General Surgery, Shengjing Hospital of China Medical University, No. 36, San Hao Street, Shenyang, Liaoning, People's Republic of China. .
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Źródło:
World journal of surgical oncology [World J Surg Oncol] 2021 Jun 14; Vol. 19 (1), pp. 177. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/diagnosis
Colonic Neoplasms*/genetics
Sodium-Calcium Exchanger*/genetics
Sodium-Calcium Exchanger*/metabolism
Down-Regulation ; Humans ; Prognosis
Czasopismo naukowe
Tytuł:
Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation.
Autorzy:
Stavsky A; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Stoler O; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Kostic M; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Katoshevsky T; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Assali EA; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Savic I; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Amitai Y; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Prokisch H; Institute of Human Genetics, School of Medicine, Technische Universität München, Munich, Germany.; Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany.
Leiz S; Department of Pediatrics, Klinikum Dritter Orden, Munich, Germany.
Daumer-Haas C; Pränatal-Medizin München, Munich, Germany.
Fleidervish I; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Perocchi F; Institute for Diabetes and Obesity, Helmholtz Diabetes Center (HDC), Helmholtz Zentrum München, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.
Gitler D; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. .; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel. .
Sekler I; Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. .; Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel. .
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Źródło:
Communications biology [Commun Biol] 2021 Jun 02; Vol. 4 (1), pp. 666. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intellectual Disability/*genetics
Intellectual Disability/*metabolism
Mitochondrial Proteins/*genetics
Mitochondrial Proteins/*metabolism
Sodium-Calcium Exchanger/*genetics
Sodium-Calcium Exchanger/*metabolism
Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Calcium Signaling ; Cardiomyopathies/genetics ; Cardiomyopathies/metabolism ; Female ; Hippocampus/metabolism ; Humans ; In Vitro Techniques ; Long-Term Potentiation ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondrial Proteins/chemistry ; Mitochondrial Proteins/deficiency ; Neuronal Plasticity ; Neurons/metabolism ; Pedigree ; Point Mutation ; Presynaptic Terminals/metabolism ; Sodium-Calcium Exchanger/chemistry ; Synaptic Transmission/genetics ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł:
Hamster Sperm Possess Functional Na -Exchanger 1: Its Implication in Hyperactivation.
Autorzy:
Takei GL; Department of Pharmacology and Toxicology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321-0293, Japan.
Ogura Y; Department of Electrical and Mechanical Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya 466-8555, Japan.
Ujihara Y; Department of Electrical and Mechanical Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya 466-8555, Japan.
Toyama F; School of Engineering, Utsunomiya University, Yoto 7-1-2, Utsunomiya 321-8585, Japan.
Hayashi K; Department of Pharmacology and Toxicology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321-0293, Japan.
Fujita T; Department of Pharmacology and Toxicology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321-0293, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 17; Vol. 24 (10). Date of Electronic Publication: 2023 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Semen*/metabolism
Spermatozoa*/metabolism
Animals ; Cricetinae ; Male ; RNA, Messenger ; Sodium-Calcium Exchanger/metabolism ; Calcium/metabolism
Czasopismo naukowe
Tytuł:
Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice.
Autorzy:
Di Martino R; Department of Neuroscience, Division of Pharmacology, Reproductive and Dentistry Sciences, School of Medicine, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
Sisalli MJ; Department of Neuroscience, Division of Pharmacology, Reproductive and Dentistry Sciences, School of Medicine, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
Sirabella R; Department of Neuroscience, Division of Pharmacology, Reproductive and Dentistry Sciences, School of Medicine, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
Della Notte S; Department of Neuroscience, Division of Pharmacology, Reproductive and Dentistry Sciences, School of Medicine, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
Borzacchiello D; Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
Feliciello A; Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
Annunziato L; IRCCS SDN, Via E. Gianturco 113, 80143 Naples, Italy.
Scorziello A; Department of Neuroscience, Division of Pharmacology, Reproductive and Dentistry Sciences, School of Medicine, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 30; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji:
Journal Article
MeSH Terms:
Mesencephalon/*metabolism
Mitochondria/*metabolism
Parkinson Disease/*metabolism
Sodium-Calcium Exchanger/*metabolism
alpha-Synuclein/*genetics
Animals ; Astrocytes/metabolism ; Calcium/metabolism ; Cells, Cultured ; Dopaminergic Neurons/metabolism ; Mesencephalon/cytology ; Mice ; Mice, Inbred C57BL ; Mutation, Missense ; Parkinson Disease/genetics ; Sodium-Calcium Exchanger/genetics ; alpha-Synuclein/metabolism
Czasopismo naukowe

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