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Tytuł:
Inward Operation of Sodium-Bicarbonate Cotransporter 1 Promotes Astrocytic Na Loading and Loss of ATP in Mouse Neocortex during Brief Chemical Ischemia.
Autorzy:
Everaerts K; Institute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Thapaliya P; Department of Physics, University of South Florida, Tampa, FL 33620, USA.
Pape N; Institute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Durry S; Institute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Eitelmann S; Institute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Roussa E; Institute of Anatomy and Cell Biology, Department of Molecular Embryology, Faculty of Medicine, Albert-Ludwigs-Universität Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany.
Ullah G; Department of Physics, University of South Florida, Tampa, FL 33620, USA.
Rose CR; Institute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
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Źródło:
Cells [Cells] 2023 Nov 21; Vol. 12 (23). Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Neocortex*/metabolism
Acidosis*/metabolism
Mice ; Animals ; Astrocytes/metabolism ; Sodium-Bicarbonate Symporters/metabolism ; Mice, Knockout ; Ions/metabolism ; Sodium/metabolism ; Adenosine Triphosphate/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lack of Charge Interaction in the Ion Binding Site Determines Anion Selectivity in the Sodium Bicarbonate Cotransporter NBCe1.
Autorzy:
Lee S; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Lin J; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Choi I; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 04; Vol. 23 (1). Date of Electronic Publication: 2022 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Binding Sites*
Ions/*chemistry
Ions/*metabolism
Sodium-Bicarbonate Symporters/*chemistry
Sodium-Bicarbonate Symporters/*metabolism
Bicarbonates/metabolism ; Biological Transport ; Humans ; Ion Channel Gating ; Membrane Potentials ; Models, Molecular ; Mutation ; Protein Binding ; Protein Domains ; Protein Interaction Domains and Motifs ; Recombinant Fusion Proteins ; Sodium/metabolism ; Sodium-Bicarbonate Symporters/genetics ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Revisiting the Role of Ser982 Phosphorylation in Stoichiometry Shift of the Electrogenic Na Cotransporter NBCe1.
Autorzy:
Alsufayan TA; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Myers EJ; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Quade BN; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Brady CT; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Marshall A; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Haque N; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Duffey ME; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Parker MD; Department of Physiology and Biophysics, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.; Department of Ophthalmology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 26; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 26.
Typ publikacji:
Journal Article
MeSH Terms:
Bicarbonates/*metabolism
Oocytes/*metabolism
Serine/*metabolism
Sodium/*metabolism
Sodium-Bicarbonate Symporters/*metabolism
Animals ; Mice ; Mice, Inbred C57BL ; Oocytes/cytology ; Phosphorylation ; Serine/genetics ; Sodium-Bicarbonate Symporters/genetics ; Xenopus laevis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The colorful mantle of the giant clam Tridacna squamosa expresses a homolog of electrogenic sodium: Bicarbonate cotransporter 2 that mediates the supply of inorganic carbon to photosynthesizing symbionts.
Autorzy:
Boo MV; Department of Biological Sciences, National University of Singapore, Singapore, Republic of Singapore.
Chew SF; Natural Sciences and Science Education, National Institute of Education, Nanyang Technological University, Singapore, Republic of Singapore.
Ip YK; Department of Biological Sciences, National University of Singapore, Singapore, Republic of Singapore.
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Źródło:
PloS one [PLoS One] 2021 Oct 15; Vol. 16 (10), pp. e0258519. Date of Electronic Publication: 2021 Oct 15 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bivalvia/*metabolism
Carbon/*metabolism
Dinoflagellida/*physiology
Sodium-Bicarbonate Symporters/*metabolism
Amino Acid Sequence ; Animals ; Bicarbonates/metabolism ; Biocatalysis ; Bivalvia/parasitology ; Cloning, Molecular ; Epithelial Cells/metabolism ; Light ; Photosynthesis/radiation effects ; Sequence Alignment ; Sodium-Bicarbonate Symporters/chemistry ; Sodium-Bicarbonate Symporters/genetics ; Symbiosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genes encoding putative bicarbonate transporters as a missing molecular link between molt and mineralization in crustaceans.
Autorzy:
Abehsera S; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel.; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Bentov S; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel.; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Li X; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing, People's Republic of China.
Weil S; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel.; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Manor R; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel.; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Sagi S; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel.
Li S; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, People's Republic of China.
Li F; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, People's Republic of China.
Khalaila I; Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Aflalo ED; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel.; Department of Life Sciences, Achva Academic College, Arugot, Israel.
Sagi A; Department of Life Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 8410501, Beer Sheva, Israel. .; The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jun 03; Vol. 11 (1), pp. 11722. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astacoidea/*physiology
Biomineralization/*genetics
Molting/*genetics
Sodium-Bicarbonate Symporters/*genetics
Animals ; Biological Transport ; Computational Biology ; Gene Expression ; Gene Expression Profiling ; Humans ; Immunohistochemistry ; Models, Biological ; Phenotype ; Phylogeny ; Sodium-Bicarbonate Symporters/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Experimental validation of in silico analysis estimated the reverse effect of upregulated hsa-miR-106a-5p and hsa-miR-223-3p on SLC4A4 gene expression in Iranian patients with colorectal adenocarcinoma by RT-qPCR.
Autorzy:
Ranjbaran J; Department of Clinical Biochemistry, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Safarpour H; Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Nomiri S; Department of Clinical Biochemistry, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Tavakoli T; Department of Internal Medicine, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Rezaei Z; Department of Biology, Faculty of Sciences, University of Sistan and Balouchestan, Zahedan, Iran.
Salmani F; Department of Epidemiology and Biostatistics, Social Determinants of Health Research Center, Faculty of Health, Birjand University of Medical Sciences, Birjand, Iran.
Larki P; Department of Molecular Genetics, Genomic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Chamani E; Department of Clinical Biochemistry, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
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Źródło:
Cancer medicine [Cancer Med] 2023 Mar; Vol. 12 (6), pp. 7005-7018. Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Adenocarcinoma*
Humans ; Iran ; Gene Expression Profiling ; Gene Expression ; Sodium-Bicarbonate Symporters/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cell-Type Dependent Regulation of the Electrogenic Na Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma.
Autorzy:
Giannaki M; Department of Molecular Embryology, Faculty of Medicine, Institute of Anatomy and Cell Biology, Albert-Ludwigs-Universität Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany.
Ruf DE; Department of Molecular Embryology, Faculty of Medicine, Institute of Anatomy and Cell Biology, Albert-Ludwigs-Universität Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany.
Pfeifer E; Department of Molecular Embryology, Faculty of Medicine, Institute of Anatomy and Cell Biology, Albert-Ludwigs-Universität Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany.
Everaerts K; Institute of Neurobiology, Heinrich Heine University, D-40225 Düsseldorf, Germany.
Heiland DH; Department of Neurosurgery, Faculty of Medicine, Medical Center, University of Freiburg, D-79106 Freiburg, Germany.; Microenvironment and Immunology Research Laboratory, Medical Center, University of Freiburg, D-79106 Freiburg, Germany.
Schnell O; Department of Neurosurgery, Faculty of Medicine, Medical Center, University of Freiburg, D-79106 Freiburg, Germany.
Rose CR; Institute of Neurobiology, Heinrich Heine University, D-40225 Düsseldorf, Germany.
Roussa E; Department of Molecular Embryology, Faculty of Medicine, Institute of Anatomy and Cell Biology, Albert-Ludwigs-Universität Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 11; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Acidosis*
Glioblastoma*
Symporters*
Humans ; Sodium/metabolism ; Sodium-Bicarbonate Symporters/genetics ; Sodium-Bicarbonate Symporters/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Installation of authentic BicA and SbtA proteins to the chloroplast envelope membrane is achieved by the proteolytic cleavage of chimeric proteins in Arabidopsis.
Autorzy:
Uehara S; Department of Agricultural and Environmental Sciences, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki, 889-2192, Japan.
Sei A; Department of Agricultural and Environmental Sciences, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki, 889-2192, Japan.
Sada M; Department of Agricultural and Environmental Sciences, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki, 889-2192, Japan.
Ito-Inaba Y; Department of Agricultural and Environmental Sciences, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki, 889-2192, Japan.
Inaba T; Department of Agricultural and Environmental Sciences, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki, 889-2192, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2020 Feb 11; Vol. 10 (1), pp. 2353. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arabidopsis/*genetics
Bacterial Proteins/*metabolism
Chloroplasts/*metabolism
Sodium-Bicarbonate Symporters/*metabolism
Bacterial Proteins/genetics ; Chloroplasts/genetics ; Peptide Hydrolases/metabolism ; Potyvirus/enzymology ; Protein Engineering/methods ; Proteolysis ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sodium-Bicarbonate Symporters/genetics ; Transgenes ; Viral Proteins/metabolism
SCR Organism:
Tobacco etch virus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Deletion of the Na/HCO 3 Transporter NBCn1 Protects Hippocampal Neurons from NMDA-induced Seizures and Neurotoxicity in Mice.
Autorzy:
Park HJ; Department of Pharmacology, Kyung Hee University School of Medicine, Seoul, South Korea.
Gonzalez-Islas CE; Doctorado en Ciencias Biologicas, Universidad Autonoma de Tlaxcala, Tlax, Mexico.; Department of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Kang Y; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Li JM; Department of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Choi I; Department of Physiology, Emory University School of Medicine, Atlanta, GA, 30322, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Nov 05; Vol. 9 (1), pp. 15981. Date of Electronic Publication: 2019 Nov 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Hippocampus/*metabolism
N-Methylaspartate/*adverse effects
Neurotoxicity Syndromes/*prevention & control
Seizures/*prevention & control
Sodium-Bicarbonate Symporters/*genetics
Animals ; Cyclic GMP/metabolism ; Gene Deletion ; Hippocampus/cytology ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; N-Methylaspartate/metabolism ; Neurons/cytology ; Neurons/metabolism ; Neurotoxicity Syndromes/etiology ; Neurotoxicity Syndromes/genetics ; Neurotoxicity Syndromes/metabolism ; Nitric Oxide Synthase/metabolism ; Seizures/etiology ; Seizures/genetics ; Seizures/metabolism ; Sodium-Bicarbonate Symporters/deficiency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Splicing Mutation in Slc4a5 Results in Retinal Detachment and Retinal Pigment Epithelium Dysfunction.
Autorzy:
Collin GB; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Shi L; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Yu M; Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Akturk N; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Charette JR; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Hyde LF; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Weatherly SM; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Pera MF; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Naggert JK; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Peachey NS; Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, 9500 Euclid Avenue, Cleveland, OH 44195, USA.; Research Service, Louis Stokes Cleveland VA Medical Center, 10701 East Boulevard, Cleveland, OH 44106, USA.
Nishina PM; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Krebs MP; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 17; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Mutation/*genetics
RNA Splicing/*genetics
Retina/*pathology
Retinal Detachment/*genetics
Retinal Pigment Epithelium/*pathology
Sodium-Bicarbonate Symporters/*genetics
Animals ; Cells, Cultured ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Retinal Detachment/pathology ; Tomography, Optical Coherence/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells.
Autorzy:
Gildea JJ; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
Xu P; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
Kemp BA; The University of Virginia Department of Medicine, Charlottesville, VA, United States of America.
Carlson JM; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
Tran HT; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
Bigler Wang D; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
Langouët-Astrié CJ; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
McGrath HE; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
Carey RM; The University of Virginia Department of Medicine, Charlottesville, VA, United States of America.
Jose PA; The George Washington University School of Medicine & Health Sciences, Department of Medicine, Division of Renal Disease and Hypertension and Department of Pharmacology and Physiology, Washington, DC, United States of America.
Felder RA; The University of Virginia Department of Pathology, Charlottesville, VA, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Apr 11; Vol. 13 (4), pp. e0189464. Date of Electronic Publication: 2018 Apr 11 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Single Nucleotide*
Bicarbonates/*metabolism
Kidney Tubules, Proximal/*cytology
Sodium/*metabolism
Sodium-Bicarbonate Symporters/*genetics
Blood Pressure/drug effects ; Blood Pressure/genetics ; Dopamine Agonists/pharmacology ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Hepatocyte Nuclear Factor 4/metabolism ; Homozygote ; Humans ; Intracellular Space/drug effects ; Intracellular Space/metabolism ; Protein Transport/drug effects ; Protein Transport/genetics ; Receptors, Dopamine/metabolism ; Sodium-Bicarbonate Symporters/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Extracellular acidosis and very low [Na ] inhibit NBCn1- and NHE1-mediated net acid extrusion from mouse vascular smooth muscle cells.
Autorzy:
Bonde L; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Boedtkjer E; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2017 Oct; Vol. 221 (2), pp. 129-141. Date of Electronic Publication: 2017 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*physiology
Sodium/*blood
Sodium-Bicarbonate Symporters/*metabolism
Sodium-Hydrogen Exchanger 1/*metabolism
Acidosis ; Animals ; Biological Transport, Active ; Cells, Cultured ; Hydrogen-Ion Concentration ; Male ; Mice ; Sodium-Bicarbonate Symporters/genetics ; Sodium-Hydrogen Exchanger 1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bicarbonate ion transport by the electrogenic Na cotransporter, NBCe1, is required for normal electrical slow-wave activity in mouse small intestine.
Autorzy:
Zhao W; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.; Neuroendocrine Pharmacology, China Medical University, Shenyang, China.
Zhang L; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.; Neuroendocrine Pharmacology, China Medical University, Shenyang, China.
Ermilov LG; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.
Colmenares Aguilar MG; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.
Linden DR; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.
Eisenman ST; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.
Romero MF; Physiology and Biomedical Engineering, Rochester, MN, USA.; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Farrugia G; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.
Sha L; Neuroendocrine Pharmacology, China Medical University, Shenyang, China.
Gibbons SJ; Enteric Neuroscience Program, Division of Gastroenterology and Hepatology, Rochester, MN, USA.; Physiology and Biomedical Engineering, Rochester, MN, USA.
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Źródło:
Neurogastroenterology and motility [Neurogastroenterol Motil] 2021 Sep; Vol. 33 (9), pp. e14149. Date of Electronic Publication: 2021 Apr 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bicarbonates/*metabolism
Gastrointestinal Motility/*physiology
Intestine, Small/*physiology
Sodium-Bicarbonate Symporters/*metabolism
Animals ; Female ; Ion Transport/physiology ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epilepsy, status epilepticus, and hemiplegic migraine coexisting with a novel SLC4A4 mutation.
Autorzy:
Gil-Perotín S; Neurology Department, University and Polytechnic Hospital La Fe, Avda. Fernando Abril Martorell, 106, 46026, Valencia, Spain. .; Neuroimmunology Unit, Health Research Institute La Fe (IISLAFE), Avda. Fernando Abril Martorell, 106, 46026, Valencia, Spain. .
Jaijo T; Genetic Unit, University and Polytechnic Hospital La Fe, Avda. Fernando Abril Martorell, 106, 46026, Valencia, Spain.; Molecular, Cellular and Genomics Biomedicine Research Group, Health Research Institute La Fe (IISLAFE), Avda. Fernando Abril Martorell, 106, 46026, Valencia, Spain.; CIBER de Enfermedades Raras (CIBERER), Madrid, Spain.
Verdú AG; Neurophysiology Department, University and Polytechnic Hospital La Fe, Avda. Fernando Abril Martorell 106, 46026, Valencia, Spain.
Rubio P; Neurophysiology Department, University and Polytechnic Hospital La Fe, Avda. Fernando Abril Martorell 106, 46026, Valencia, Spain.
Mazón M; Radiology Department, Hospital Arnau de Vilanova, C/San Clemente, 12, 46025, Valencia, Spain.
Gasqué-Rubio R; Neuroimmunology Unit, Health Research Institute La Fe (IISLAFE), Avda. Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Díaz S; Neurology Department, University and Polytechnic Hospital La Fe, Avda. Fernando Abril Martorell, 106, 46026, Valencia, Spain.
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Sep; Vol. 42 (9), pp. 3647-3654. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji:
Journal Article
MeSH Terms:
Epilepsy*/complications
Epilepsy*/genetics
Migraine with Aura*
Status Epilepticus*/complications
Status Epilepticus*/genetics
Adult ; Hemiplegia ; Humans ; Mutation/genetics ; Sodium-Bicarbonate Symporters
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of Nt-truncation and coexpression of isolated Nt domains on the membrane trafficking of electroneutral Na+/HCO3- cotransporters.
Autorzy:
Wang DK; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Liu Y; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Myers EJ; Department of Physiology and Biophysics, School of Medicine, University at Buffalo: The State University of New York, Buffalo, NY 14214, USA.
Guo YM; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Xie ZD; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Jiang DZ; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Li JM; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Yang J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100091, China.
Liu M; Department of Genetics and Developmental Biology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
Parker MD; Department of Physiology and Biophysics, School of Medicine, University at Buffalo: The State University of New York, Buffalo, NY 14214, USA.
Chen LM; Department of Biophysics and Molecular Physiology, Key Laboratory of Molecular Biophysics of Ministry of Education, Huazhong University of Science and Technology School of Life Science and Technology, Wuhan, Hubei 430074, China.
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Źródło:
Scientific reports [Sci Rep] 2015 Jul 20; Vol. 5, pp. 12241. Date of Electronic Publication: 2015 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Membrane/*metabolism
Sodium-Bicarbonate Symporters/*chemistry
Sodium-Bicarbonate Symporters/*metabolism
Alternative Splicing/genetics ; Amino Acid Sequence ; Animals ; Base Sequence ; Biotinylation ; Exons/genetics ; Fluorescence ; Genes, Reporter ; HEK293 Cells ; Humans ; Kidney/metabolism ; Luciferases/metabolism ; Mice ; Molecular Sequence Data ; Mutant Proteins/chemistry ; Mutant Proteins/metabolism ; Oocytes/metabolism ; Promoter Regions, Genetic ; Protein Binding ; Protein Structure, Tertiary ; Protein Transport ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Sodium-Bicarbonate Symporters/genetics ; Transcription, Genetic ; Xenopus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Duodenal mucosal secretory disturbances in functional dyspepsia.
Autorzy:
Puthanmadhom Narayanan S; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Linden DR; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Peters SA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Desai A; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Kuwelker S; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
O'Brien D; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Smyrk TJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Graham RP; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Grover M; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Bharucha AE; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
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Źródło:
Neurogastroenterology and motility [Neurogastroenterol Motil] 2021 Jan; Vol. 33 (1), pp. e13955. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Duodenum/*metabolism
Dyspepsia/*genetics
Intestinal Mucosa/*metabolism
Acetylcholine ; Adult ; Case-Control Studies ; Chloride-Bicarbonate Antiporters/genetics ; Cholinergic Agonists ; Down-Regulation ; Dyspepsia/metabolism ; Female ; Glucose ; Humans ; Ion Transport/genetics ; Male ; MicroRNAs/genetics ; Middle Aged ; RNA, Messenger/metabolism ; Receptors, Serotonin, 5-HT4/genetics ; Serotonin Plasma Membrane Transport Proteins/genetics ; Sodium-Bicarbonate Symporters/genetics ; Sulfate Transporters/genetics ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of NBCe1 deletion on renal citrate and 2-oxoglutarate handling.
Autorzy:
Osis G; Division of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.
Handlogten ME; Division of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.
Lee HW; Division of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.
Hering-Smith KS; Renal Division, Tulane University College of Medicine, New Orleans, Louisiana.
Huang W; Renal Division, Tulane University College of Medicine, New Orleans, Louisiana.
Romero MF; Department of Physiology & Biomedical Engineering and Nephrology & Hypertension, Mayo Clinic College Of Medicine, Rochester, Minnesota.
Verlander JW; Division of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.
Weiner ID; Division of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida Nephrology and Hypertension Section, North Florida/South Georgia Veterans Health System, Gainesville, Florida .
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Źródło:
Physiological reports [Physiol Rep] 2016 Apr; Vol. 4 (8).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Citric Acid/*metabolism
Ketoglutaric Acids/*metabolism
Kidney/*metabolism
Sodium-Bicarbonate Symporters/*metabolism
Acidosis/genetics ; Acidosis/metabolism ; Animals ; Immunoblotting ; Immunohistochemistry ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Real-Time Polymerase Chain Reaction ; Sodium-Bicarbonate Symporters/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of Sodium Bicarbonate Cotransporters in Intracellular pH Regulation and Their Regulatory Mechanisms in Human Submandibular Glands.
Autorzy:
Namkoong E; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Shin YH; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Bae JS; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Choi S; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Kim M; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Kim N; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Hwang SM; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
Park K; Department of Physiology, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, 110-749, Korea.
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Źródło:
PloS one [PLoS One] 2015 Sep 16; Vol. 10 (9), pp. e0138368. Date of Electronic Publication: 2015 Sep 16 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Mouth Neoplasms/*metabolism
Sodium-Bicarbonate Symporters/*metabolism
Submandibular Gland/*metabolism
Bicarbonates/metabolism ; Cell Membrane/metabolism ; Cells, Cultured ; Cytoplasm/metabolism ; Fluorescent Antibody Technique ; Humans ; Hydrogen-Ion Concentration ; Immunoenzyme Techniques ; Immunoprecipitation ; Mouth Neoplasms/pathology ; Phosphorylation ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Sodium-Bicarbonate Symporters/genetics ; Submandibular Gland/pathology ; Tyrosine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Therapeutic effect of prenatal alkalization and PTC124 in Na(+)/HCO3(-) cotransporter 1 p.W516* knock-in mice.
Autorzy:
Fang YW; 1] Division of Nephrology, Department of Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan [2] Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan.
Yang SS; 1] Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan [2] Division of Nephrology, Department of Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Chau T; Department of Medicine, Providence St Vincent Medical Center, Portland, OR, USA.
Nakamura M; Department of Internal Medicine, Faculty of Medicine, Tokyo University, Tokyo, Japan.
Yamazaki O; Department of Internal Medicine, Faculty of Medicine, Tokyo University, Tokyo, Japan.
Seki G; Department of Internal Medicine, Faculty of Medicine, Tokyo University, Tokyo, Japan.
Yamada H; Department of Internal Medicine, Faculty of Medicine, Tokyo University, Tokyo, Japan.
Hsu HM; Division of Nephrology, Department of Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Cheng CJ; 1] Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan [2] Division of Nephrology, Department of Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Lin SH; 1] Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan [2] Division of Nephrology, Department of Medicine, Tri-Service General Hospital, Taipei, Taiwan.
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Źródło:
Gene therapy [Gene Ther] 2015 May; Vol. 22 (5), pp. 374-81. Date of Electronic Publication: 2015 Feb 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Therapy*
Acidosis, Renal Tubular/*therapy
Oxadiazoles/*therapeutic use
Sodium-Bicarbonate Symporters/*genetics
Acidosis, Renal Tubular/genetics ; Alkalies/blood ; Alkalies/urine ; Animals ; Gentamicins/administration & dosage ; Gentamicins/therapeutic use ; Mice ; Oxadiazoles/administration & dosage ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Sodium-Bicarbonate Symporters/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Application of weighted gene co‑expression network analysis to explore the potential diagnostic biomarkers for colorectal cancer.
Autorzy:
Qin L; Molecular Laboratory, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, Zhejiang 311121, P.R. China.
Zeng J; Department of Neurosurgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 311121, P.R. China.
Shi N; Molecular Laboratory, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, Zhejiang 311121, P.R. China.
Chen L; Molecular Laboratory, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, Zhejiang 311121, P.R. China.
Wang L; Molecular Laboratory, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, Zhejiang 311121, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2020 Jun; Vol. 21 (6), pp. 2533-2543. Date of Electronic Publication: 2020 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor/*genetics
Colorectal Neoplasms/*diagnosis
Biomarkers, Tumor/metabolism ; Cluster Analysis ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Collagen Type I, alpha 1 Chain ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/mortality ; Databases, Genetic ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Gene Regulatory Networks/genetics ; Humans ; Polycomb Repressive Complex 1/genetics ; Polycomb Repressive Complex 1/metabolism ; Sodium-Bicarbonate Symporters/genetics ; Sodium-Bicarbonate Symporters/metabolism ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 92

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