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Wyświetlanie 1-20 z 180681

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Tytuł:
Amorphous System of Hesperetin and Piperine-Improvement of Apparent Solubility, Permeability, and Biological Activities.
Autorzy:
Wdowiak K; Department of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
Miklaszewski A; Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24, 61-138 Poznan, Poland.
Pietrzak R; Faculty of Chemistry, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego 8, 61-614 Poznan, Poland.
Cielecka-Piontek J; Department of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 02; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Solubility*
Spectroscopy, Fourier Transform Infrared ; Permeability ; Biological Availability
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preparation of Free-Flowing Spray-Dried Amorphous Composites Using Neusilin .
Autorzy:
Lin Z; New Jersey Center for Engineered Particulates, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Zheng K; New Jersey Center for Engineered Particulates, New Jersey Institute of Technology, Newark, NJ, 07102, USA.
Azad MA; Chemical, Biological and Bioengineering Department, North Carolina A&T State University, Greensboro, NC, 27411, USA.
Davé RN; New Jersey Center for Engineered Particulates, New Jersey Institute of Technology, Newark, NJ, 07102, USA. .
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Źródło:
AAPS PharmSciTech [AAPS PharmSciTech] 2023 Jan 26; Vol. 24 (1), pp. 51. Date of Electronic Publication: 2023 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Solubility*
Powders/chemistry ; Particle Size
Czasopismo naukowe
Szczegóły
Tytuł:
Tablet characteristics and pharmacokinetics of orally disintegrating tablets containing coenzyme Q10 granules prepared by different methods.
Autorzy:
Kashiwagura Y; Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences University of Shizuoka; 52-1 Yada Suruga-ku, Shizuoka 422-8526, Japan.
Takusagawa S; Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences University of Shizuoka; 52-1 Yada Suruga-ku, Shizuoka 422-8526, Japan.
Ikematsu Y; Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences University of Shizuoka; 52-1 Yada Suruga-ku, Shizuoka 422-8526, Japan.; CMC Regulatory, Pharmaceutical Science and Technology CFU, Medicine Development Center, Eisai Co., Ltd. 4-6-10 Koishikawa, Bunkyo-ku, Tokyo 112-8088, Japan.
Tanaka S; Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences University of Shizuoka; 52-1 Yada Suruga-ku, Shizuoka 422-8526, Japan.
Namiki N; Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences University of Shizuoka; 52-1 Yada Suruga-ku, Shizuoka 422-8526, Japan.; Faculty of Pharmaceutical Sciences, Teikyo Heisei University, 4-21-2, Nakano Nakano-ku, Tokyo 164-8530, Japan.
Uchida S; Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences University of Shizuoka; 52-1 Yada Suruga-ku, Shizuoka 422-8526, Japan.
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Źródło:
Acta pharmaceutica (Zagreb, Croatia) [Acta Pharm] 2023 Jan 24; Vol. 73 (1), pp. 107-119. Date of Electronic Publication: 2023 Jan 24 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Solubility*
Drug Compounding/methods ; Hardness ; Tablets ; Administration, Oral
Czasopismo naukowe
Szczegóły
Tytuł:
Challenges and Strategies for Solubility Measurements and Dissolution Method Development for Amorphous Solid Dispersion Formulations.
Autorzy:
Hermans A; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey, USA. andre_.
Milsmann J; Analytical Development, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Li H; Technical Operations, Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Jede C; Analytical Development, Chemical and Pharmaceutical Development, Merck KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.
Moir A; Oral Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, UK.
Hens B; Drug Product Design, Pfizer UK, Sandwich, UK.
Morgado J; Analytical R&D, Pfizer, Groton, Connecticut, USA.
Wu T; AffaMed Therapeutics Inc., Sacramento, California, USA.
Cohen M; Global Chemistry and Manufacturing Controls, Pfizer, Groton, Connecticut, USA.
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Źródło:
The AAPS journal [AAPS J] 2022 Dec 13; Vol. 25 (1), pp. 11. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Solubility*
Crystallization ; Drug Liberation
Czasopismo naukowe
Szczegóły
Tytuł:
Purely Predicting the Pharmaceutical Solubility: What to Expect from PC-SAFT and COSMO-RS?
Autorzy:
Klajmon M; Department of Physical Chemistry, Faculty of Chemical Engineering, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2022 Nov 07; Vol. 19 (11), pp. 4212-4232. Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Solubility*
Thermodynamics ; Solvents ; Pharmaceutical Preparations
Czasopismo naukowe
Szczegóły
Tytuł:
Dissolution behavior of representative elements from red mud (RM) by leaching with titanium white waste acid (TWWA).
Autorzy:
Zhu X; School of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, 454000, Henan, China.; State Environmental Protection Key Laboratory of Mineral Metallurgical Resources Utilization and Pollution Control, Wuhan University of Science and Technology Wuhan, Hubei, 430081, China.; Collaborative Innovation Center of Coal Work Safety and Clean High Efficiency Utilization, Jiaozuo, 454000, Henan, China.
Ma C; School of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, 454000, Henan, China.
Li W; School of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, 454000, Henan, China. .; State Environmental Protection Key Laboratory of Mineral Metallurgical Resources Utilization and Pollution Control, Wuhan University of Science and Technology Wuhan, Hubei, 430081, China. .
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Źródło:
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Oct; Vol. 29 (49), pp. 74264-74275. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
Solubility*
Diffusion ; Kinetics ; Titanium
Czasopismo naukowe
Szczegóły
Tytuł:
Synchronization of Cocrystal Dissolution and Drug Precipitation to Sustain Drug Supersaturation.
Autorzy:
Cogo Machado T; Programa de Pós-Graduação em Farmácia, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Kavanagh ON; School of Pharmacy, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom.
Gonçalves Cardoso S; Programa de Pós-Graduação em Farmácia, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Rodríguez-Hornedo N; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109-1065, United States.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2022 Aug 01; Vol. 19 (8), pp. 2765-2775. Date of Electronic Publication: 2022 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Solubility*
Crystallization ; Drug Compounding
Czasopismo naukowe
Szczegóły
Tytuł:
A PI Control Method with HGSO Parameter Regulator for Trajectory Planning of 9-DOF Redundant Manipulator.
Autorzy:
Liu M; CAS Key Laboratory of On-Orbit Manufacturing and Integration for Space Optics System, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China.; School of Optoelectronics, University of Chinese Academy of Sciences, Beijing 100049, China.
Liu T; CAS Key Laboratory of On-Orbit Manufacturing and Integration for Space Optics System, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China.; School of Optoelectronics, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhu M; CAS Key Laboratory of On-Orbit Manufacturing and Integration for Space Optics System, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China.
Chen L; CAS Key Laboratory of On-Orbit Manufacturing and Integration for Space Optics System, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2022 Sep 10; Vol. 22 (18). Date of Electronic Publication: 2022 Sep 10.
Typ publikacji:
Journal Article
MeSH Terms:
Solubility*
Biomechanical Phenomena
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanisms and Extent of Enhanced Passive Permeation by Colloidal Drug Particles.
Autorzy:
Narula A; Department of Pharmaceutical Sciences, University of Connecticut, 69 North Eagleville Road Unit 3092, Storrs, Connecticut 06269, United States.
Sabra R; Department of Pharmaceutical Sciences, University of Connecticut, 69 North Eagleville Road Unit 3092, Storrs, Connecticut 06269, United States.
Li N; Department of Pharmaceutical Sciences, University of Connecticut, 69 North Eagleville Road Unit 3092, Storrs, Connecticut 06269, United States.; Institute of Materials Science, University of Connecticut, 97 North Eagleville Road Unit 3136, Storrs, Connecticut 06269, United States.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2022 Sep 05; Vol. 19 (9), pp. 3085-3099. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Solubility*
Diffusion ; Drug Compounding ; Lopinavir/chemistry ; Membranes
Czasopismo naukowe
Szczegóły
Tytuł:
Study of Formulation and Process Variables for Optimization of Piroxicam Nanosuspension Using 3 2 Factorial Design to Improve Solubility and In Vitro Bioavailability.
Autorzy:
Alhamhoom, Yahya (AUTHOR)
Honmane, Sandip M. (AUTHOR)
Hani, Umme (AUTHOR)
Osmani, Riyaz Ali M. (AUTHOR)
Kandasamy, Geetha (AUTHOR)
Vasudevan, Rajalakshimi (AUTHOR)
Paramshetti, Sharanya (AUTHOR)
R. Dudhal, Ravindra (AUTHOR)
K. Kengar, Namrata (AUTHOR)
Charde, Manoj S. (AUTHOR)
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Źródło:
Polymers (20734360). Feb2023, Vol. 15 Issue 3, p483. 16p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions.
Autorzy:
Asim, Muhammad (AUTHOR)
Nazir, Marriam (AUTHOR)
Chauhdary, Zunera (AUTHOR)
Irfan, Muhammad (AUTHOR)
Khalid, Syed Haroon (AUTHOR)
Asghar, Sajid (AUTHOR)
Usra (AUTHOR)
Felimban, Raed I. (AUTHOR)
Majrashi, Mohammed A (AUTHOR)
Hazzazi, Mohannad S. (AUTHOR)
Alissa, Mohammed (AUTHOR)
Qahl, Safa H (AUTHOR)
Hussain, Ghulam (AUTHOR)
Rasul, Azhar (AUTHOR)
Chatha, Shahzad Ali Shahid (AUTHOR)
Khan, Ikram Ullah (AUTHOR)
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Źródło:
Pharmaceutics. Feb2023, Vol. 15 Issue 2, p399. 21p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Voriconazole Cyclodextrin Based Polymeric Nanobeads for Enhanced Solubility and Activity: In Vitro/In Vivo and Molecular Simulation Approach.
Autorzy:
Farooq, Mudassir (AUTHOR)
Usman, Faisal (AUTHOR)
Naseem, Mahrukh (AUTHOR)
Aati, Hanan Y. (AUTHOR)
Ahmad, Hassan (AUTHOR)
Manee, Sirikhwan (AUTHOR)
Khalil, Ruqaiya (AUTHOR)
Khan, Kashif ur Rehman (AUTHOR)
Qureshi, Muhammad Imran (AUTHOR)
Umair, Muhammad (AUTHOR)
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Źródło:
Pharmaceutics. Feb2023, Vol. 15 Issue 2, p389. 20p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Celecoxib Nanoformulations with Enhanced Solubility, Dissolution Rate, and Oral Bioavailability: Experimental Approaches over In Vitro/In Vivo Evaluation.
Autorzy:
Arslan, Aslıhan (AUTHOR)
Yet, Barbaros (AUTHOR)
Nemutlu, Emirhan (AUTHOR)
Akdağ Çaylı, Yağmur (AUTHOR)
Eroğlu, Hakan (AUTHOR)
Öner, Levent (AUTHOR)
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Źródło:
Pharmaceutics. Feb2023, Vol. 15 Issue 2, p363. 27p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment.
Autorzy:
Dhibar, Manami (AUTHOR)
Chakraborty, Santanu (AUTHOR)
Basak, Souvik (AUTHOR)
Pattanayak, Paramita (AUTHOR)
Chatterjee, Tanmay (AUTHOR)
Ghosh, Balaram (AUTHOR)
Raafat, Mohamed (AUTHOR)
Abourehab, Mohammed A. S. (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Feb2023, Vol. 16 Issue 2, p284. 25p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Improving Lurasidone Hydrochloride's Solubility and Stability by Higher-Order Complex Formation with Hydroxypropyl-β-cyclodextrin.
Autorzy:
Gamboa-Arancibia, María Elena (AUTHOR)
Caro, Nelson (AUTHOR)
Gamboa, Alexander (AUTHOR)
Morales, Javier Octavio (AUTHOR)
González Casanova, Jorge Enrique (AUTHOR)
Rojas Gómez, Diana Marcela (AUTHOR)
Miranda-Rojas, Sebastián (AUTHOR)
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Źródło:
Pharmaceutics. Jan2023, Vol. 15 Issue 1, p232. 27p.
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Solubility of Hydrophobes into Macrocyclic Hosts.
Autorzy:
Yao Y; Department of Chemistry, Zhejiang University, Hangzhou, 310028, P. R. China.
Zhang X; Department of Chemistry, Zhejiang University, Hangzhou, 310028, P. R. China.
Mochizuki K; Department of Chemistry, Zhejiang University, Hangzhou, 310028, P. R. China.
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Źródło:
The journal of physical chemistry. B [J Phys Chem B] 2022 Apr 07; Vol. 126 (13), pp. 2557-2563. Date of Electronic Publication: 2022 Mar 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Solubility*
Hydrophobic and Hydrophilic Interactions ; Solutions ; Solvents/chemistry ; Thermodynamics
Czasopismo naukowe
Szczegóły
Tytuł:
DISSOLUTION PROFILE SIMILARITY ANALYSES-STATISTICAL PRINCIPLES, METHODS AND CONSIDERATIONS.
Autorzy:
Hoffelder T; Global Biostatistics and Data Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Binger Straße 173, 55216, Ingelheim Am Rhein, Germany. .
Leblond D; Consultant in CMC Statistical Studies, 3091 Midlane Drive, Wadsworth, IL, 60083, United States of America.
Van Alstine L; Pfizer Inc, Eastern Point Road, Groton, Connecticut, 06340, United States of America.
Diaz DA; Pfizer Inc, Eastern Point Road, Groton, Connecticut, 06340, United States of America.
Suarez-Sharp S; Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.; Regulatory Affairs, Simulations Plus Inc, 42505 10th Street West, Lancaster, CA, 93534, United States of America.
Witkowski K; Center for Mathematical Sciences, Merck Manufacturing Division, Merck & Co., Inc, Kenilworth, NJ, 07033, United States of America.
Altan S; Statistics and Decision Sciences, Manufacturing and Applied Statistics, Janssen Pharmaceutical R&D LLD, Raritan, NJ, 08869, United States of America.
Reynolds J; Data and Statistical Sciences, AbbVie Inc, North Chicago, IL, 60064, United States of America.
Bergeron Z; Agios Pharmaceuticals, 88 Sidney St., Cambridge, MA, 02143, United States of America.; Sage Therapeutics, 215 First St, Cambridge, MA, 02142, United States of America.
Lief K; CMC Statistics, Biostatistics, GlaxoSmithKline, David Jack Centre for R&D, Ware, SG12 0DP, Hertfordshire, UK.
Zheng Y; Data and Statistical Sciences, AbbVie Inc, North Chicago, IL, 60064, United States of America.
Abend A; Pharmaceutical Sciences, Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA, 19486, United States of America.
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Źródło:
The AAPS journal [AAPS J] 2022 Apr 06; Vol. 24 (3), pp. 54. Date of Electronic Publication: 2022 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
Solubility*
Baltimore
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 180681

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