Temat: "Solubility" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set.
Autorzy:: Zhao J; Department of Pharmacy, Uppsala University, 751 23 Uppsala, Sweden.
Hermans E; Pharmaceutical & Material Sciences, Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
Sepassi K; Discovery Pharmaceutics, Janssen Research & Development, LLC, La Jolla, California 92121, United States.
Tistaert C; Pharmaceutical & Material Sciences, Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
Bergström CAS; Department of Pharmacy, Uppsala University, 751 23 Uppsala, Sweden.
Ahmad M; In Silico Discovery, Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
Larsson P; Department of Pharmacy, Uppsala University, 751 23 Uppsala, Sweden.; Pokaż więcej
Źródło:: Molecular pharmaceutics [Mol Pharm] 2024 Oct 07; Vol. 21 (10), pp. 5261-5271. Date of Electronic Publication: 2024 Sep 13.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Data Accuracy ; Computer Simulation ; Pharmaceutical Preparations/chemistry

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Skocz do pozycji: 2.

Tytuł:: A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis.
Autorzy:: Larsen BS; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Sem Sælands vei 3, 0371 Oslo, Norway. Electronic address: .
Meiland P; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark; Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej 26, 1958 Frederiksberg C, Denmark.
Tzdaka E; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Sem Sælands vei 3, 0371 Oslo, Norway.
Tho I; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Sem Sælands vei 3, 0371 Oslo, Norway. Electronic address: .
Rades T; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.; Pokaż więcej
Źródło:: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Oct; Vol. 203, pp. 114478. Date of Electronic Publication: 2024 Sep 01.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Polymers*/chemistry
Pharmaceutical Preparations/chemistry ; Workflow ; Crystallization ; Chemistry, Pharmaceutical/methods ; Software ; Transition Temperature

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Skocz do pozycji: 3.

Tytuł:: Optimization of drug solubility inside the supercritical CO 2 system via numerical simulation based on artificial intelligence approach.
Autorzy:: Li M; Department of Human Anatomy and Embryology, Pu Ai Medical School, Shaoyang University, Shaoyang, 422000, Hunan, China.
Jiang W; The Second Affiliated Hospital of Shaoyang University, Shaoyang University, Shaoyang, 422000, Hunan, China. .
Zhao S; Department of Human Anatomy and Embryology, Pu Ai Medical School, Shaoyang University, Shaoyang, 422000, Hunan, China.
Huang K; Department of Human Anatomy and Embryology, Pu Ai Medical School, Shaoyang University, Shaoyang, 422000, Hunan, China.
Liu D; Shashi Town Health Center, Shaodong, 422813, Hunan, China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Oct 01; Vol. 14 (1), pp. 22779. Date of Electronic Publication: 2024 Oct 01.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Dioxide*/chemistry
Solubility*
Algorithms ; Artificial Intelligence ; Niflumic Acid/chemistry ; Computer Simulation ; Solvents/chemistry ; Temperature

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Skocz do pozycji: 4.

Tytuł:: Co-amorphous systems of sulfasalazine with matrine-type alkaloids: Enhanced solubility behaviors and synergistic therapeutic potential.
Autorzy:: Chen X; Innovation Centre for Science and Technology, North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China. Electronic address: .
Qin Y; Innovation Centre for Science and Technology, North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China; Institute of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China.
Wang L; Innovation Centre for Science and Technology, North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China; Institute of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China.
Zhu Y; Laboratory of Pharmaceutical Solid-State Chemistry, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, P. R. China.
Zhang H; Laboratory of Pharmaceutical Solid-State Chemistry, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, P. R. China; Interdisciplinary Institute of NMR and Molecular Sciences (NMR-X), School of Chemistry and Chemical Engineering, State Key Laboratory of Refractories and Metallurgy, Wuhan University of Science and Technology, Wuhan 430081, P. R. China.
Liu W; School of Pharmacy, North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China. Electronic address: wh_.
Zeng M; Innovation Centre for Science and Technology, North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China; Institute of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China.
Dai Q; Institute of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637100, P. R. China. Electronic address: .; Pokaż więcej
Źródło:: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Oct; Vol. 203, pp. 114475. Date of Electronic Publication: 2024 Aug 30.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Alkaloids*/chemistry
Alkaloids*/administration & dosage
Sulfasalazine*/chemistry
Sulfasalazine*/administration & dosage
Quinolizines*/chemistry
Quinolizines*/administration & dosage
Matrines*
Calorimetry, Differential Scanning*
X-Ray Diffraction*/methods
Spectroscopy, Fourier Transform Infrared/methods ; Drug Synergism ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Arthritis, Rheumatoid/drug therapy

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Skocz do pozycji: 5.

Tytuł:: Effect of cooking conditions on chickpea flour functionality and its protein physicochemical properties.
Autorzy:: Hong S; Department of Grain Science and Industry, Kansas State University, Manhattan, Kansas, USA.
Xiao R; Department of Grain Science and Industry, Kansas State University, Manhattan, Kansas, USA.
Chen G; Department of Grain Science and Industry, Kansas State University, Manhattan, Kansas, USA.
Zhu Y; PepsiCo R&D, PepsiCo, Plano, Texas, USA.
Garay A; PepsiCo R&D, PepsiCo, Plano, Texas, USA.
Yang J; PepsiCo R&D, PepsiCo, Plano, Texas, USA.
Xu Y; Healthy Processed Foods Research Unit, Western Regional Research Center, USDA-ARS, Albany, California, USA.
Li Y; Department of Grain Science and Industry, Kansas State University, Manhattan, Kansas, USA.; Pokaż więcej
Źródło:: Journal of food science [J Food Sci] 2024 Oct; Vol. 89 (10), pp. 6253-6267. Date of Electronic Publication: 2024 Aug 26.
Typ publikacji:: Journal Article
MeSH Terms:: Cicer*/chemistry
Flour*/analysis
Cooking*/methods
Solubility*
Plant Proteins*/analysis
Plant Proteins*/chemistry
Viscosity ; Seeds/chemistry ; Water/chemistry ; Water/analysis ; Hot Temperature ; Nutritive Value

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Skocz do pozycji: 6.

Tytuł:: AlphaFold 2-based stacking model for protein solubility prediction and its transferability on seed storage proteins.
Autorzy:: Kwon H; Department of Grain Science and Industry, Kansas State University, Manhattan, KS 66506, USA.
Du Z; Department of Grain Science and Industry, Kansas State University, Manhattan, KS 66506, USA.
Li Y; Department of Grain Science and Industry, Kansas State University, Manhattan, KS 66506, USA. Electronic address: .; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 1), pp. 134601. Date of Electronic Publication: 2024 Aug 11.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Seed Storage Proteins*/chemistry
Molecular Dynamics Simulation ; Computational Biology/methods ; Escherichia coli Proteins/chemistry ; Support Vector Machine ; Neural Networks, Computer

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Skocz do pozycji: 7.

Tytuł:: Evaluating solubility, stability, and inclusion complexation of oxyresveratrol with various β-cyclodextrin derivatives using advanced computational techniques and experimental validation.
Autorzy:: Ali S; Center of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Aman A; Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand.
Hengphasatporn K; Center for Computational Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan.
Oopkaew L; Center of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Todee B; Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Rd, Bangkok 10400, Thailand.
Fujiki R; Center for Computational Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan.
Harada R; Center for Computational Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan.
Shigeta Y; Center for Computational Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan.
Krusong K; Center of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Choowongkomon K; Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Chavasiri W; Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Wolschann P; Institute of Theoretical Chemistry, University of Vienna, Vienna 1090, Austria.
Mahalapbutr P; Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: .
Rungrotmongkol T; Center of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand; Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: .; Pokaż więcej
Źródło:: Computational biology and chemistry [Comput Biol Chem] 2024 Oct; Vol. 112, pp. 108111. Date of Electronic Publication: 2024 Jun 01.
Typ publikacji:: Journal Article
MeSH Terms:: beta-Cyclodextrins*/chemistry
Solubility*
Stilbenes*/chemistry
Molecular Docking Simulation*
Humans ; Molecular Dynamics Simulation ; Cell Proliferation/drug effects ; Molecular Structure ; Plant Extracts/chemistry ; Drug Screening Assays, Antitumor ; Drug Stability

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Skocz do pozycji: 8.

Tytuł:: Improved photostability, solubility, hygroscopic stability and antimicrobial activity of fleroxacin by synthesis of fleroxacin-D-tartaric acid pharmaceutical salt.
Autorzy:: Liu L; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China. Electronic address: .
Wang Y; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Sun J; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Zhang Y; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China. Electronic address: .
Zhang X; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Wu L; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Liu Y; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Zhang X; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Xia Y; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Zhang Q; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.
Gao N; College of Pharmacy, Jiamusi University, Heilongjiang Province, Jiamusi 154007, China.; Pokaż więcej
Źródło:: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Oct; Vol. 203, pp. 114464. Date of Electronic Publication: 2024 Aug 22.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Tartrates*/chemistry
Drug Stability*
Fleroxacin*/chemistry
Microbial Sensitivity Tests/methods ; Wettability ; X-Ray Diffraction/methods ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Escherichia coli/drug effects ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/chemical synthesis ; Spectroscopy, Fourier Transform Infrared/methods ; Staphylococcus aureus/drug effects ; Salts/chemistry ; Chemistry, Pharmaceutical/methods

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Skocz do pozycji: 9.

Tytuł:: Rational design approach to improve the solubility of the β-sandwich domain 1 of a thermophilic protein.
Autorzy:: Ononugbo CM; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Shimura Y; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Yamano-Adachi N; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Omasa T; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Koga Y; Department of Applied Chemistry, Faculty of Engineering, Okayama University of Science, 1-1 Ridaicho, Kitaku, Okayama 700-0005, Japan. Electronic address: .; Pokaż więcej
Źródło:: Journal of bioscience and bioengineering [J Biosci Bioeng] 2024 Oct; Vol. 138 (4), pp. 271-282. Date of Electronic Publication: 2024 Jul 29.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Escherichia coli*/genetics
Escherichia coli*/metabolism
Protein Stability*
Protein Domains*
Hydrogen-Ion Concentration ; Protein Engineering/methods ; Protein Folding ; Mutation ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism

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Skocz do pozycji: 10.

Tytuł:: Intelligence computational analysis of letrozole solubility in supercritical solvent via machine learning models.
Autorzy:: Alqarni M; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia. .
Ashour AA; Department of Oral & Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Shafie A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O.Box 11099, Taif, 21944, Saudi Arabia.
Alqarni A; Department of Oral & Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Felemban MF; Department of Oral & Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Shukr BS; Department of Preventive Dentistry, Faculty of Dentistry, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Alzubaidi MA; Department of Preventive Dentistry, Faculty of Dentistry, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Algahtani FS; Department of Restorative Dental Science, Faculty of Dentistry, Taif University, Taif, 21944, Saudi Arabia.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Sep 17; Vol. 14 (1), pp. 21677. Date of Electronic Publication: 2024 Sep 17.
Typ publikacji:: Journal Article
MeSH Terms:: Letrozole*/chemistry
Solubility*
Solvents*/chemistry
Machine Learning*
Support Vector Machine ; Algorithms

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Skocz do pozycji: 11.

Tytuł:: Enhancing ketoprofen's solubility and anti-inflammatory efficacy with safe methyl-β-cyclodextrin complexation.
Autorzy:: Rajamohan R; School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea. .
Kamaraj E; School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Muthuraja P; School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Murugavel K; PG & Research Department of Chemistry, Government Arts College, Chidambaram, 608 102, Tamil Nadu, India.
Govindasamy C; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, 11433, Riyadh, Saudi Arabia.
Prabakaran DS; Department of Radiation Oncology, College of Medicine, Chungbuk National University, Chungdae-ro Seowon-gu, Cheongju, 28644, Republic of Korea.; Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Chennai, 603203, Tamil Nadu, India.
Malik T; Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia. .; Division of Research & Development, Lovely Professional University, Phagwara, India, 144411. .
Lee YR; School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Sep 14; Vol. 14 (1), pp. 21516. Date of Electronic Publication: 2024 Sep 14.
Typ publikacji:: Journal Article
MeSH Terms:: Ketoprofen*/chemistry
Ketoprofen*/pharmacology
beta-Cyclodextrins*/chemistry
Solubility*
Anti-Inflammatory Agents, Non-Steroidal*/chemistry
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Animals ; Spectroscopy, Fourier Transform Infrared ; Rats

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Skocz do pozycji: 12.

Tytuł:: Exploring Co-Amorphous Formulations Of Nevirapine: Insights From Computational, Thermal, And Solubility Analyses.
Autorzy:: Dos Santos KA; Quality Control Core of Medicines and Correlates - NCQMC, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Chaves LL; Quality Control Core of Medicines and Correlates - NCQMC, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.; Postgraduate Program in Pharmaceutical Sciences, Pharmaceutical Sciences Institute, Federal University of Alagoas, Maceió, Alagoas, Brazil.
Nadvorny D; Postgraduate Program in Pharmaceutical Sciences, Pharmaceutical Sciences Institute, Federal University of Alagoas, Maceió, Alagoas, Brazil.
de La Roca Soares MF; Quality Control Core of Medicines and Correlates - NCQMC, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.; Postgraduate Program in Pharmaceutical Sciences, Pharmaceutical Sciences Institute, Federal University of Alagoas, Maceió, Alagoas, Brazil.
Sobrinho JLS; Quality Control Core of Medicines and Correlates - NCQMC, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil. .; Pokaż więcej
Źródło:: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Sep 12; Vol. 25 (7), pp. 214. Date of Electronic Publication: 2024 Sep 12.
Typ publikacji:: Journal Article
MeSH Terms:: Nevirapine*/chemistry
Solubility*
Calorimetry, Differential Scanning*/methods
X-Ray Diffraction*/methods
Chemistry, Pharmaceutical*/methods
Spectroscopy, Fourier Transform Infrared/methods ; Drug Compounding/methods ; Lamivudine/chemistry ; Hydrogen Bonding ; Anti-HIV Agents/chemistry

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Skocz do pozycji: 13.

Tytuł:: Evaluation of the physical properties of bromelain-modified biodentine for direct pulp capping.
Autorzy:: Agrawal P; Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442107, India. .
Chandak M; Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442107, India.
Patel A; Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442107, India.
Bhopatkar J; Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442107, India.; Pokaż więcej
Źródło:: BMC oral health [BMC Oral Health] 2024 Sep 09; Vol. 24 (1), pp. 1053. Date of Electronic Publication: 2024 Sep 09.
Typ publikacji:: Journal Article
MeSH Terms:: Silicates*/chemistry
Silicates*/therapeutic use
Calcium Compounds*/chemistry
Calcium Compounds*/therapeutic use
Solubility*
Compressive Strength*
Bromelains*/therapeutic use
Bromelains*/chemistry
Materials Testing*
Dental Pulp Capping/methods ; Pulp Capping and Pulpectomy Agents/therapeutic use ; Pulp Capping and Pulpectomy Agents/chemistry ; Humans

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Skocz do pozycji: 14.

Tytuł:: 6-Carboxycellulose Acetate Butyrate: Effectiveness as an Amorphous Solid Dispersion Polymer.
Autorzy:: Marks JA; Macromolecules Innovation Institute, Department of Sustainable Biomaterials, College of Natural Resources and Environment, Virginia Tech, Blacksburg, Virginia 24061, United States.; Department of Chemistry, University of the West Indies, Mona, Kingston JMAAW15, Jamaica.
Nichols BLB; Department of Chemistry, College of Science, Virginia Tech, Blacksburg, Virginia 24061, United States.
Mosquera-Giraldo LI; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
T Yazdi S; Macromolecules Innovation Institute, Department of Sustainable Biomaterials, College of Natural Resources and Environment, Virginia Tech, Blacksburg, Virginia 24061, United States.
Taylor LS; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
Edgar KJ; Macromolecules Innovation Institute, Department of Sustainable Biomaterials, College of Natural Resources and Environment, Virginia Tech, Blacksburg, Virginia 24061, United States.; Pokaż więcej
Źródło:: Molecular pharmaceutics [Mol Pharm] 2024 Sep 02; Vol. 21 (9), pp. 4589-4602. Date of Electronic Publication: 2024 Aug 01.
Typ publikacji:: Journal Article
MeSH Terms:: Solubility*
Polymers*/chemistry
Cellulose*/chemistry
Cellulose*/analogs & derivatives
Ibuprofen*/chemistry
Ibuprofen*/pharmacokinetics
Loratadine*/chemistry
Loratadine*/analogs & derivatives
Loratadine*/pharmacokinetics
Drug Liberation ; Quercetin/chemistry ; Clarithromycin/chemistry ; Ritonavir/chemistry ; Chemistry, Pharmaceutical/methods ; Drug Compounding/methods

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Skocz do pozycji: 15.

Tytuł:: COSMOPharm: Drug-Polymer Compatibility of Pharmaceutical Amorphous Solid Dispersions from COSMO-SAC.
Autorzy:: Antolović I; Thermodynamics, Technische Universität Berlin, Ernst-Reuter-Platz 1, 10587 Berlin, Germany.
Vrabec J; Thermodynamics, Technische Universität Berlin, Ernst-Reuter-Platz 1, 10587 Berlin, Germany.
Klajmon M; Department of Physical Chemistry, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague 6, Czechia.; Pokaż więcej
Źródło:: Molecular pharmaceutics [Mol Pharm] 2024 Sep 02; Vol. 21 (9), pp. 4395-4415. Date of Electronic Publication: 2024 Jul 30.
Typ publikacji:: Journal Article
MeSH Terms:: Polymers*/chemistry
Solubility*
Thermodynamics*
Chemistry, Pharmaceutical/methods ; Drug Carriers/chemistry ; Pharmaceutical Preparations/chemistry

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Tytuł:: Experimental and model-based approach to evaluate solvent effects on the solubility of the pharmaceutical artemisinin.
Autorzy:: Wünsche S; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Tenberg V; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Oliynyk K; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Seidel-Morgenstern A; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Lorenz H; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.
Sadeghi M; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany. Electronic address: .; Pokaż więcej
Źródło:: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2024 Sep 01; Vol. 200, pp. 106826. Date of Electronic Publication: 2024 Jun 10.
Typ publikacji:: Journal Article
MeSH Terms:: Artemisinins*/chemistry
Solvents*/chemistry
Solubility*
Antimalarials*/chemistry
Ethanol/chemistry ; Heptanes/chemistry ; Toluene/chemistry ; Models, Chemical ; Artemisia annua/chemistry ; Crystallization

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Tytuł:: Comparison of two self-nanoemulsifying drug delivery systems using different solidification techniques for enhanced solubility and oral bioavailability of poorly water-soluble celecoxib.
Autorzy:: Woo MR; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Woo S; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Bak YW; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Cheon S; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Kim JS; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Ji SH; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Park S; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea.
Kim JO; College of Pharmacy, Yeungnam University, 214-1, Dae-Dong, Gyongsan 712-749, South Korea.
Jin SG; Department of Pharmaceutical Engineering, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, South Korea. Electronic address: .
Choi HG; College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, South Korea. Electronic address: .; Pokaż więcej
Źródło:: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2024 Sep; Vol. 241, pp. 114044. Date of Electronic Publication: 2024 Jun 17.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Celecoxib*/chemistry
Celecoxib*/pharmacokinetics
Celecoxib*/administration & dosage
Solubility*
Biological Availability*
Emulsions*/chemistry
Rats, Sprague-Dawley*
Water*/chemistry
Drug Delivery Systems*
Animals ; Administration, Oral ; Male ; Rats ; Particle Size ; Surface-Active Agents/chemistry ; Nanoparticles/chemistry ; Polysorbates/chemistry

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Skocz do pozycji: 18.

Tytuł:: Evaluating the ability of different chaperones in improving soluble expression of a triple-mutated human interferon gamma in Escherichia coli.
Autorzy:: Yasamut U; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Center of Innovative Immunodiagnostic Development, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Thongheang K; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Weechan A; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Sornsuwan K; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Juntit OA; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Tayapiwatana C; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Center of Biomolecular Therapy and Diagnostic, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Center of Innovative Immunodiagnostic Development, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand. Electronic address: .; Pokaż więcej
Źródło:: Journal of bioscience and bioengineering [J Biosci Bioeng] 2024 Sep; Vol. 138 (3), pp. 232-238. Date of Electronic Publication: 2024 Jul 04.
Typ publikacji:: Journal Article
MeSH Terms:: Escherichia coli*/genetics
Escherichia coli*/metabolism
Interferon-gamma*/metabolism
Interferon-gamma*/genetics
Molecular Chaperones*/genetics
Molecular Chaperones*/metabolism
Solubility*
Humans ; Mutation ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Plasmids/genetics

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Skocz do pozycji: 19.

Tytuł:: Mirtazapine loaded polymeric micelles for rapid release tablet: A novel formulation-In vitro and in vivo studies.
Autorzy:: El-Helaly SN; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. .
Rashad AA; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Heliopolis University, El Salam City, Cairo, Egypt.; Pokaż więcej
Źródło:: Drug delivery and translational research [Drug Deliv Transl Res] 2024 Sep; Vol. 14 (9), pp. 2488-2498. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Micelles*
Mirtazapine*/pharmacokinetics
Mirtazapine*/administration & dosage
Mirtazapine*/chemistry
Tablets*
Solubility*
Biological Availability*
Animals ; Rabbits ; Male ; Drug Liberation ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacokinetics ; Polyethylene Glycols/administration & dosage ; Polymers/chemistry ; Particle Size ; Surface-Active Agents/chemistry ; Administration, Oral ; Stearic Acids/chemistry ; Stearic Acids/pharmacokinetics ; Chemistry, Pharmaceutical/methods

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Tytuł:: β-Lactoglobulin-based amorphous solid dispersions: A graphical review on the state-of-the-art.
Autorzy:: Zhuo X; Zerion Pharma A/S, Fruebjergvej 3, 2100 Copenhagen, Denmark.
Jasiukenaite I; Zerion Pharma A/S, Fruebjergvej 3, 2100 Copenhagen, Denmark.
Löbmann K; Zerion Pharma A/S, Fruebjergvej 3, 2100 Copenhagen, Denmark. Electronic address: .; Pokaż więcej
Źródło:: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Sep; Vol. 202, pp. 114396. Date of Electronic Publication: 2024 Jul 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Lactoglobulins*/chemistry
Solubility*
Excipients*/chemistry
Biological Availability ; Drug Compounding/methods ; Chemistry, Pharmaceutical/methods ; Drug Liberation ; Drug Stability ; Polymers/chemistry ; Spray Drying

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Solubility.