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    Wyświetlanie 1-7 z 7
    Tytuł:
    Animal Models for the Investigation of P2X7 Receptors.
    Autorzy:
    Sluyter R; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.
    Adriouch S; UniRouen, INSERM, U1234, Pathophysiology, Autoimmunity, and Immunotherapy, (PANTHER), Univ Rouen Normandie, University of Rouen, F-76000 Rouen, France.
    Fuller SJ; Sydney Medical School Nepean, Faculty of Medicine and Health, The University of Sydney, Nepean Hospital, Kingswood, NSW 2750, Australia.
    Nicke A; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, LMU Munich, 80336 Munich, Germany.
    Sophocleous RA; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.
    Watson D; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 May 04; Vol. 24 (9). Date of Electronic Publication: 2023 May 04.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Receptors, Purinergic P2X7*/genetics
    Zebrafish*
    Mice ; Rats ; Humans ; Animals ; Dogs ; Guinea Pigs ; Rabbits ; Macaca mulatta ; Models, Animal ; Mice, Knockout ; Adenosine Triphosphate
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist.
    Autorzy:
    Cuthbertson P; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Elhage A; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Al-Rifai D; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Sophocleous RA; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Turner RJ; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Aboelela A; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, Assiut 71515, Egypt.
    Majed H; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Bujaroski RS; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.; Monash Institute of Pharmaceutical Science (ATMCF), Monash University, Parkville, VIC 3052, Australia.
    Jalilian I; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Kelso MJ; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Watson D; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Buckley BJ; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Sluyter R; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
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    Źródło:
    Biomolecules [Biomolecules] 2022 Sep 16; Vol. 12 (9). Date of Electronic Publication: 2022 Sep 16.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Purinergic P2X Receptor Antagonists*/pharmacology
    Receptors, Purinergic P2X7*
    Adenosine ; Adenosine Triphosphate/metabolism ; Amiloride/analogs & derivatives ; Amiloride/pharmacology ; Animals ; Dogs ; HEK293 Cells ; Humans ; Interleukin-1beta/metabolism ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The P2X4 Receptor: Cellular and Molecular Characteristics of a Promising Neuroinflammatory Target.
    Autorzy:
    Sophocleous RA; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Ooi L; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Sluyter R; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 May 20; Vol. 23 (10). Date of Electronic Publication: 2022 May 20.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Adenosine Triphosphate*/metabolism
    Receptors, Purinergic P2X4*/genetics
    Receptors, Purinergic P2X4*/metabolism
    Humans ; Signal Transduction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    P2Y 2 and P2X4 Receptors Mediate Ca Mobilization in DH82 Canine Macrophage Cells.
    Autorzy:
    Sophocleous RA; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Miles NA; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Ooi L; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
    Sluyter R; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2020 Nov 13; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Calcium Signaling*
    Calcium/*metabolism
    Macrophages/*metabolism
    Receptors, Purinergic P2X4/*metabolism
    Receptors, Purinergic P2Y2/*metabolism
    Animals ; Cell Line ; Dogs ; Macrophages/cytology ; Purinergic P2X Receptor Antagonists/pharmacology ; Purinergic P2Y Receptor Antagonists/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Pharmacological and genetic characterisation of the canine P2X4 receptor.
    Autorzy:
    Sophocleous RA; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Berg T; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Finol-Urdaneta RK; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Electrophysiology Facility for Cell Phenotyping and Drug Discovery, Wollongong, NSW, Australia.
    Sluyter V; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Keshiya S; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Bell L; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Curtis SJ; Albion Park Veterinary Hospital, Albion Park, NSW, Australia.
    Curtis BL; Albion Park Veterinary Hospital, Albion Park, NSW, Australia.
    Seavers A; Oak Flats Veterinary Clinic, Oak Flats, NSW, Australia.
    Bartlett R; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Dowton M; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Stokes L; School of Pharmacy, University of East Anglia, Norwich, UK.
    Ooi L; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Sluyter R; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia.
    Pokaż więcej
    Źródło:
    British journal of pharmacology [Br J Pharmacol] 2020 Jun; Vol. 177 (12), pp. 2812-2829. Date of Electronic Publication: 2020 Mar 10.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Purinergic P2X Receptor Antagonists*
    Receptors, Purinergic P2X4*/genetics
    Adenosine Triphosphate ; Animals ; Dogs ; HEK293 Cells ; Humans ; Receptors, Purinergic P2X7
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Association of a P2RX7 gene missense variant with brachycephalic dog breeds.
    Autorzy:
    Sophocleous RA; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Sluyter V; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Curtis BL; Albion Park Veterinary Hospital, Albion Park, NSW, 2527, Australia.
    Curtis SJ; Albion Park Veterinary Hospital, Albion Park, NSW, 2527, Australia.
    Jurak LM; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Faulks M; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Spildrejorde M; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Gates S; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Proctor EJ; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Seavers A; Oak Flats Veterinary Clinic, Oak Flats, NSW, 2529, Australia.
    Watson D; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Kuit T; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Dowton M; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
    Stokes L; School of Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
    Sluyter R; Illawarra Health and Medical Research Institute, Wollongong, NSW, 2522, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2522, Australia.
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    Źródło:
    Animal genetics [Anim Genet] 2020 Feb; Vol. 51 (1), pp. 127-131. Date of Electronic Publication: 2019 Nov 27.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Mutation, Missense*
    Craniosynostoses/*veterinary
    Dog Diseases/*genetics
    Dogs/*genetics
    Receptors, Purinergic P2X7/*genetics
    Animals ; Breeding ; Craniosynostoses/genetics ; Pedigree
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Ferlins Show Tissue-Specific Expression and Segregate as Plasma Membrane/Late Endosomal or Trans-Golgi/Recycling Ferlins.
    Autorzy:
    Redpath GM; Institute for Neuroscience and Muscle Research, Kid's Research Institute, Children's Hospital at Westmead, Sydney, Australia.; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, Australia.
    Sophocleous RA; Institute for Neuroscience and Muscle Research, Kid's Research Institute, Children's Hospital at Westmead, Sydney, Australia.
    Turnbull L; Microbial Imaging Facility, The iThree Institute, University of Technology Sydney, Ultimo, Australia.
    Whitchurch CB; Microbial Imaging Facility, The iThree Institute, University of Technology Sydney, Ultimo, Australia.
    Cooper ST; Institute for Neuroscience and Muscle Research, Kid's Research Institute, Children's Hospital at Westmead, Sydney, Australia.; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, Australia.
    Pokaż więcej
    Źródło:
    Traffic (Copenhagen, Denmark) [Traffic] 2016 Mar; Vol. 17 (3), pp. 245-66.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Calcium-Binding Proteins/*metabolism
    Cell Membrane/*metabolism
    Endosomes/*metabolism
    Membrane Proteins/*metabolism
    Muscle Proteins/*metabolism
    trans-Golgi Network/*metabolism
    Amino Acid Sequence ; Animals ; Brain/metabolism ; COS Cells ; Calcium-Binding Proteins/chemistry ; Calcium-Binding Proteins/genetics ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Mice ; Molecular Sequence Data ; Muscle Proteins/chemistry ; Muscle Proteins/genetics ; Organ Specificity ; Pancreas/metabolism ; Protein Transport ; rab GTP-Binding Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-7 z 7

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