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Tytuł :
Multiobjective semisupervised learning with a right-censored endpoint adapted to the multiple imputation framework.
Autorzy :
Faucheux L; Université de Paris, Statistic and epidemiologic research center, INSERM UMR-1153, ECSTRRA Team, Paris, France.; Université de Paris, INSERM U976, Paris, France.
Soumelis V; Université de Paris, INSERM U976, Paris, France.; Laboratoire d'immunologie, biologie et histocompatibilité, AP-HP, Hôpital Saint-Louis, Paris, France.
Chevret S; Université de Paris, Statistic and epidemiologic research center, INSERM UMR-1153, ECSTRRA Team, Paris, France.; Service de Biostatistique et Information Médicale, AP-HP, Hôpital Saint-Louis, Paris, France.
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Źródło :
Biometrical journal. Biometrische Zeitschrift [Biom J] 2021 Jun 27. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The discovery of human TSLP as a critical epithelial cytokine in type 2 immunity and allergic disease.
Autorzy :
Soumelis V; HIPI Unit, Inserm U976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France. vassili.soumelis@aphp.fr.; Laboratoire d'Immunologie et Histocompatibilité, AP-HP, Hôpital St Louis, Paris, France. vassili.soumelis@aphp.fr.
Liu YJ; Sanofi R&D, Cambridge, MA, USA. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Dec; Vol. 21 (12), pp. 1471-1473.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Compartmentalized multicellular crosstalk in lymph nodes coordinates the generation of potent cellular and humoral immune responses.
Autorzy :
Poirot J; Université de Paris, INSERM U976, Paris, F-75006, France.; Université Paris-Saclay, Saint Aubin, 91190, France.
Medvedovic J; Université de Paris, INSERM U976, Paris, F-75006, France.
Trichot C; Université de Paris, INSERM U976, Paris, F-75006, France.
Soumelis V; Université de Paris, INSERM U976, Paris, F-75006, France.; AP-HP, Hôpital Saint-Louis, Laboratoire d'Immunologie-Histocompatibilité, Paris, 75010, France.
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Źródło :
European journal of immunology [Eur J Immunol] 2021 Oct 04. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Autorzy :
Asano T; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Boisson B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA. .; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Onodi F; Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR7212, University of Paris, Research Institute of Saint-Louis, Saint-Louis Hospital, Paris, France.
Matuozzo D; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Moncada-Velez M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Maglorius Renkilaraj MRL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Zhang P; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Meertens L; Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR7212, University of Paris, Research Institute of Saint-Louis, Saint-Louis Hospital, Paris, France.
Bolze A; Helix, San Mateo, CA, USA.
Materna M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Korniotis S; University of Paris, INSERM U976, F-75006 Paris, France.
Gervais A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Talouarn E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Bigio B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Seeleuthner Y; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Bilguvar K; Yale Center for Genome Analysis and Department of Genetics, Yale School of Medicine, New Haven, CT, USA.
Zhang Y; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.
Neehus AL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Ogishi M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Pelham SJ; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Le Voyer T; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Rosain J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Philippot Q; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Soler-Palacín P; Infection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia Spain.; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Autonomous University of Barcelona (UAB), Barcelona, Catalonia, Spain.; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain.
Colobran R; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain.; Diagnostic Immunology Group, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain.; Immunology Division, Genetics Department, Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Barcelona Hospital Campus, Autonomous University of Barcelona (UAB), Barcelona, Catalonia, Spain.
Martin-Nalda A; Infection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia Spain.; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Autonomous University of Barcelona (UAB), Barcelona, Catalonia, Spain.; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain.
Rivière JG; Infection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia Spain.; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron University Hospital (HUVH), Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Autonomous University of Barcelona (UAB), Barcelona, Catalonia, Spain.; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain.
Tandjaoui-Lambiotte Y; AP-HP, Avicenne Hospital, Intensive Care Unit, Bobigny, France.; INSERM U1272 Hypoxia & Lung, Bobigny, France.
Chaïbi K; Anesthesiology and Critical Care Medicine Department, APHP, Avicenne Hospital, Bobigny, France.; Common and Rare Kidney Diseases, Sorbonne University, INSERM UMR-S 1155, Paris, France.
Shahrooei M; Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz, Iran.; Department of Microbiology and Immunology, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.
Darazam IA; Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Department of Infectious Diseases and Tropical Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Olyaei NA; Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz, Iran.; Department of Microbiology and Immunology, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.
Mansouri D; Department of Clinical Immunology and Infectious Diseases, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; The Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti, University of Medical Sciences, Tehran, Iran.; Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti, Iran.
Hatipoğlu N; Pediatric Infectious Diseases Unit, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Palabiyik F; Pediatric Infectious Diseases Unit, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Ozcelik T; Department of Molecular Biology and Genetics, University of Bilkent, Bilkent-Ankara, Turkey.
Novelli G; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata,' Rome, and Neuromed Institute, IRCCS, Pozzilli (IS), Italy.
Novelli A; Laboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy.
Casari G; Vita-Salute San Raffaele University, Milan, Italy.; Clinical Genomics, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Aiuti A; Vita-Salute San Raffaele University, Milan, Italy.; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) and Pediatric Immunohematology Unit and BMT Program, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Carrera P; Clinical Genomics, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Bondesan S; Clinical Genomics, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Barzaghi F; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) and Pediatric Immunohematology Unit and BMT Program, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Rovere-Querini P; Vita-Salute San Raffaele University, Milan, Italy.; Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Tresoldi C; Molecular Hematology Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Franco JL; Primary Immunodeficiencies Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia, Medellín, Colombia.
Rojas J; Primary Immunodeficiencies Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia, Medellín, Colombia.
Reyes LF; Universidad de La Sabana, Chia, Colombia.
Bustos IG; Universidad de La Sabana, Chia, Colombia.
Arias AA; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Primary Immunodeficiencies Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia, Medellín, Colombia.; School of Microbiology, University of Antioquia UdeA, Medellín, Colombia.
Morelle G; Department of General Pediatrics, Hôpital Bicêtre, AP-HP, University of Paris Saclay, Le Kremlin-Bicêtre, France.
Christèle K; Department of General Pediatrics, Hôpital Bicêtre, AP-HP, University of Paris Saclay, Le Kremlin-Bicêtre, France.
Troya J; Department of Internal Medicine, Infanta Leonor University Hospital, Madrid, Spain.
Planas-Serra L; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Center for Biomedical Research on Rare Diseases (CIBERER), ISCIII, Spain.
Schlüter A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Center for Biomedical Research on Rare Diseases (CIBERER), ISCIII, Spain.
Gut M; CNAG-CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 4, 08028, Barcelona, Spain.
Pujol A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Center for Biomedical Research on Rare Diseases (CIBERER), ISCIII, Spain.; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.
Allende LM; Immunology Department, University Hospital 12 de Octubre, Research Institute Hospital 12 de Octubre (I+12), Madrid, Spain.; Complutense University, Madrid, Spain.
Rodriguez-Gallego C; Department of Immunology, University Hospital of Gran Canaria Dr. Negrín, Canarian Health System, Las Palmas de Gran Canaria, Spain.; Department of Clinical Sciences, University of Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.
Flores C; Genomics Division, Institute of Technology and Renewable Energies (ITER), Santa Cruz de Tenerife, Spain.; CIBER de Enfermedades Respiratorias, Health Institute of Carlos III, Madrid, Spain.; Research Unit, University Hospital of N.S. de Candelaria, Santa Cruz de Tenerife, Spain.; Institute of Biomedical technologies (ITB), University of La Laguna, San Cristóbal de La Laguna, Spain.
Cabrera-Marante O; Immunology Department, University Hospital 12 de Octubre, Research Institute Hospital 12 de Octubre (I+12), Madrid, Spain.
Pleguezuelo DE; Immunology Department, University Hospital 12 de Octubre, Research Institute Hospital 12 de Octubre (I+12), Madrid, Spain.
de Diego RP; Institute of Biomedical Research of IdiPAZ, University Hospital 'La Paz', Madrid, Spain.
Keles S; Necmettin Erbakan University, Meram Medical Faculty, Division of Pediatric Allergy and Immunology, Konya, Turkey.
Aytekin G; Konya City Hospital, Division of Allergy and Immunology, Konya, Turkey.
Akcan OM; Necmettin Erbakan University, Meram Medical Faculty, Division of Pediatric Allergy and Immunology, Konya, Turkey.
Bryceson YT; Centre for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.
Bergman P; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden.; The Immunodeficiency Unit, Infectious Disease Clinic, Karolinska University Hospital, Stockholm, Sweden.
Brodin P; Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institute, Solna, Sweden.
Smole D; Central Hospital-Anesthesia and Intensive Care Unit, Karlstad, Sweden.
Smith CIE; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institute, Stockholm, Sweden.; The Immunodeficiency Unit, Infectious Disease Clinic, Karolinska University Hospital, Stockholm, Sweden.
Norlin AC; The Immunodeficiency Unit, Infectious Disease Clinic, Karolinska University Hospital, Stockholm, Sweden.
Campbell TM; Centre for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.
Covill LE; Centre for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.
Hammarström L; Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden.
Pan-Hammarström Q; Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden.
Abolhassani H; Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden.; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Mane S; Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.
Marr N; Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar.
Ata M; Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar.
Al Ali F; Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar.
Khan T; Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar.
Spaan AN; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands.
Dalgard CL; Department of Anatomy, Physiology & Genetics Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The American Genome Center, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Bonfanti P; Department of Infectious Diseases, San Gerardo Hospital-University of Milano-Bicocca, Monza, Italy.
Biondi A; Pediatric Department and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM- Ospedale San Gerardo, Monza, Italy.
Tubiana S; Centre d'Investigation Clinique, INSERM CIC 1425, Paris, France.; Hôpital Bichat Claude Bernard, APHP, Paris, France.
Burdet C; Centre d'Investigation Clinique, INSERM CIC 1425, Paris, France.; Université de Paris, IAME, INSERM UMR 1137, Paris, France.
Nussbaum R; Invitae, San Francisco, CA, USA.
Kahn-Kirby A; Invitae, San Francisco, CA, USA.
Snow AL; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Bustamante J; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.; Center for the Study of Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France, EU.
Puel A; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Boisson-Dupuis S; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Zhang SY; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Béziat V; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Lifton RP; Yale Center for Genome Analysis and Department of Genetics, Yale School of Medicine, New Haven, CT, USA.; Laboratory of Genetics and Genomics, The Rockefeller University, New York, NY, USA.
Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.
Abel L; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Su HC; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jouanguy E; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Amara A; Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR7212, University of Paris, Research Institute of Saint-Louis, Saint-Louis Hospital, Paris, France.
Soumelis V; University of Paris, INSERM U976, F-75006 Paris, France.; APHP, Hôpital Saint-Louis, Department of Immunology-Histocompatibility, 75010 Paris, France.
Cobat A; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Zhang Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Casanova JL; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA. .; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.; Howard Hughes Medical Institute, New York, NY, USA.
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Corporate Authors :
COVID Human Genetic Effort
COVID-STORM Clinicians
COVID Clinicians
Imagine COVID Group
French COVID Cohort Study Group
CoV-Contact Cohort
Amsterdam UMC Covid-
Biobank
NIAID-USUHS COVID Study Group
Źródło :
Science immunology [Sci Immunol] 2021 Aug 19; Vol. 6 (62).
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*complications
Genetic Diseases, X-Linked/*complications
Immune System Diseases/*complications
Toll-Like Receptor 7/*deficiency
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alleles ; Child ; Child, Preschool ; Humans ; Infant ; Male ; Middle Aged ; Pedigree ; Penetrance ; Toll-Like Receptor 7/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Machine Learning Approaches in Study of Multiple Sclerosis Disease Through Magnetic Resonance Images.
Autorzy :
Moazami F; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale (INSERM) U976, Hôpital Saint-Louis, Paris, France.
Lefevre-Utile A; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale (INSERM) U976, Hôpital Saint-Louis, Paris, France.; Université Paris-Saclay, Saint Aubin, France.; Assistance Publique Hopitaux de Paris (APHP), General Pediatric and Pediatric Emergency Department, Jean Verdier Hospital, Bondy, France.
Papaloukas C; Department of Biological Applications and Technology, University of Ioannina, Ioannina, Greece.
Soumelis V; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale (INSERM) U976, Hôpital Saint-Louis, Paris, France.; Assistance Publique Hopitaux de Paris (APHP), Hôpital Saint-Louis, Immunology-Histocompatibility Department, Paris, France.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Aug 11; Vol. 12, pp. 700582. Date of Electronic Publication: 2021 Aug 11 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
A computational workflow for the detection of candidate diagnostic biomarkers of Kawasaki disease using time-series gene expression data.
Autorzy :
Pezoulas VC; Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Ioannina GR45110, Greece.
Papaloukas C; Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Ioannina GR45110, Greece.; Department of Biological Applications and Technology, University of Ioannina, Ioannina GR45100, Greece.
Veyssiere M; INSERM U976, Human Immunology, Physiopathology and Immunotherapy, Paris, France.
Goules A; Department of Pathophysiology, School of Medicine, University of Athens, Athens GR15772, Greece.
Tzioufas AG; Department of Pathophysiology, School of Medicine, University of Athens, Athens GR15772, Greece.
Soumelis V; INSERM U976, Human Immunology, Physiopathology and Immunotherapy, Paris, France.; Hôpital Saint Louis, Saint Louis Research Institute, Paris, France.
Fotiadis DI; Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Ioannina GR45110, Greece.; Department of Biomedical Research, FORTH (Foundation for Research & Technology)-IMBB (Institute of Molecular Biology and Biotechnology), Ioannina GR45110, Greece.
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Źródło :
Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2021 May 24; Vol. 19, pp. 3058-3068. Date of Electronic Publication: 2021 May 24 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Modeling the Th17 and Tregs Paradigm: Implications for Cancer Immunotherapy.
Autorzy :
Corral-Jara KF; Computational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure, CNRS UMR 8197, INSERM U1024, Ecole Normale Supérieure, PSL Research University, Paris, France.
Rosas da Silva G; School of Biological Sciences, Queen's University Belfast, Belfast, United Kingdom.
Fierro NA; Department of Immunology, Biomedical Research Institute, National Autonomous University of Mexico, Mexico City, Mexico.
Soumelis V; Université de Paris, INSERM U976, France and AP-HP, Hôpital Saint-Louis, Immunology-Histocompatibility Department, Paris, France.
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Źródło :
Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 May 07; Vol. 9, pp. 675099. Date of Electronic Publication: 2021 May 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity.
Autorzy :
Saichi M; Université de Paris, INSERM U976, Paris, France.
Ladjemi MZ; Institut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris, Paris, France.; Service de Médecine Intensive & Réanimation, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris. Centre & Université de Paris, Paris, France.
Korniotis S; Université de Paris, INSERM U976, Paris, France.
Rousseau C; Institut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris, Paris, France.
Ait Hamou Z; Institut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris, Paris, France.; Service de Médecine Intensive & Réanimation, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris. Centre & Université de Paris, Paris, France.
Massenet-Regad L; Université de Paris, INSERM U976, Paris, France.; Université Paris-Saclay, Saint-Aubin, France.
Amblard E; Université de Paris, INSERM U976, Paris, France.; Université de Paris, Centre de Recherches Interdisciplinaires, Paris, France.
Noel F; Université de Paris, INSERM U976, Paris, France.
Marie Y; Institut du Cerveau (ICM), Plateforme de Génotypage Séquençage, Paris, France.; Sorbonne Universités, Université Pierre et Marie Curie, Paris, France.
Bouteiller D; Institut du Cerveau (ICM), Plateforme de Génotypage Séquençage, Paris, France.
Medvedovic J; Université de Paris, INSERM U976, Paris, France.
Pène F; Institut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris, Paris, France.; Service de Médecine Intensive & Réanimation, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris. Centre & Université de Paris, Paris, France.
Soumelis V; Université de Paris, INSERM U976, Paris, France. vassili.soumelis@aphp.fr.; AP-HP, Hôpital Saint-Louis, Laboratoire d'Immunologie-Histocompatibilité, Paris, France. vassili.soumelis@aphp.fr.
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Źródło :
Nature cell biology [Nat Cell Biol] 2021 May; Vol. 23 (5), pp. 538-551. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen Presentation/*genetics
Antigen Presentation/*immunology
Antigens, Viral/*immunology
Antiviral Agents/*immunology
COVID-19/*blood
COVID-19/*immunology
Dendritic Cells/immunology ; Humans ; Monocytes/immunology ; Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods
Czasopismo naukowe
Tytuł :
Systems analysis of human T helper17 cell differentiation uncovers distinct time-regulated transcriptional modules.
Autorzy :
Capone A; Molecular Neuroimmunology Unit, IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143 Rome, Italy.; Department of Biology and Biotechnology Charles Darwin, Sapienza University, Rome, Italy.
Naro C; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168 Rome, Italy.; IRCCS Fondazione Policlinico Agostino Gemelli, Rome, Italy.
Bianco M; Molecular Neuroimmunology Unit, IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143 Rome, Italy.
De Bardi M; Neuroimmunology Unit, IRCCS Santa Lucia Foundation, Rome, Italy.
Noël F; Laboratoire d'Immunologie et Histocompatibilité, AP-HP, Hôpital St Louis, Paris, France.; HIPI Unit, Inserm U976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Macchi P; Laboratory of Molecular and Cellular Neurobiology, Centre for Integrative Biology, University of Trento, Trento, Italy.
Battistini L; Neuroimmunology Unit, IRCCS Santa Lucia Foundation, Rome, Italy.
Soumelis V; Laboratoire d'Immunologie et Histocompatibilité, AP-HP, Hôpital St Louis, Paris, France.; HIPI Unit, Inserm U976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France.
Volpe E; Molecular Neuroimmunology Unit, IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano 64, 00143 Rome, Italy.
Sette C; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168 Rome, Italy.; Neuroembriology Unit, IRCCS Santa Lucia Foundation, Rome, Italy.
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Źródło :
IScience [iScience] 2021 Apr 30; Vol. 24 (5), pp. 102492. Date of Electronic Publication: 2021 Apr 30 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4.
Autorzy :
Onodi F; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U976, Hôpital Saint-Louis, Paris, France.
Bonnet-Madin L; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U944, Centre National de la Recherche Scientifique 7212, Hôpital Saint-Louis, Paris, France.
Meertens L; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U944, Centre National de la Recherche Scientifique 7212, Hôpital Saint-Louis, Paris, France.
Karpf L; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U976, Hôpital Saint-Louis, Paris, France.
Poirot J; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U976, Hôpital Saint-Louis, Paris, France.
Zhang SY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, Necker Hospital for Sick Children, Paris, France.; Université de Paris, Institut National de la Santé et de la Recherche Médicale Unite Mixte de Recherche 1163, Institut Imagine, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
Picard C; Université de Paris, Institut National de la Santé et de la Recherche Médicale Unite Mixte de Recherche 1163, Institut Imagine, Paris, France.; Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris, Paris, France.
Puel A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, Necker Hospital for Sick Children, Paris, France.; Université de Paris, Institut National de la Santé et de la Recherche Médicale Unite Mixte de Recherche 1163, Institut Imagine, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
Jouanguy E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, Necker Hospital for Sick Children, Paris, France.; Université de Paris, Institut National de la Santé et de la Recherche Médicale Unite Mixte de Recherche 1163, Institut Imagine, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
Zhang Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
Le Goff J; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U976, Hôpital Saint-Louis, Paris, France.; Laboratoire de Virologie et Département des Maladies Infectieuses, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Molina JM; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U944, Centre National de la Recherche Scientifique 7212, Hôpital Saint-Louis, Paris, France.; Laboratoire de Virologie et Département des Maladies Infectieuses, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Delaugerre C; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U944, Centre National de la Recherche Scientifique 7212, Hôpital Saint-Louis, Paris, France.; Laboratoire de Virologie et Département des Maladies Infectieuses, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, Necker Hospital for Sick Children, Paris, France.; Université de Paris, Institut National de la Santé et de la Recherche Médicale Unite Mixte de Recherche 1163, Institut Imagine, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.; Howard Hughes Medical Institute, New York, NY.
Amara A; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U944, Centre National de la Recherche Scientifique 7212, Hôpital Saint-Louis, Paris, France.
Soumelis V; Université de Paris, Institut de Recherche Saint-Louis, Institut National de la Santé et de la Recherche Médicale U976, Hôpital Saint-Louis, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Laboratoire d'Immunologie, Paris, France.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2021 Apr 05; Vol. 218 (4).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
COVID-19/*metabolism
Cell Plasticity/*immunology
Dendritic Cells/*immunology
Dendritic Cells/*metabolism
Interleukin-1 Receptor-Associated Kinases/*metabolism
Membrane Transport Proteins/*metabolism
SARS-CoV-2/*immunology
Biomarkers ; COVID-19/drug therapy ; COVID-19/virology ; Cytokines/metabolism ; Dendritic Cells/virology ; Host-Pathogen Interactions/immunology ; Humans ; Hydroxychloroquine/pharmacology ; Hydroxychloroquine/therapeutic use ; Immunomodulation ; Immunophenotyping ; Inflammation Mediators/metabolism ; Interferon Type I/metabolism ; Interferons/metabolism
Czasopismo naukowe
Tytuł :
Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites.
Autorzy :
Ottman N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Barrientos-Somarribas M; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Fyhrquist N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Human Microbiome Research Program, University of Helsinki, Helsinki, Finland.
Alexander H; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Wisgrill L; Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Medical University of Vienna, Vienna, Austria.
Olah P; Department of Dermatology, University Hospital Duesseldorf, Duesseldorf, Germany.; Department of Dermatology, Venereology and Oncodermatology, University of Pécs, Pécs, Hungary.
Tsoka S; Department of Informatics, Faculty of Natural and Mathematical Sciences, King's College London, London, UK.
Greco D; Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Institute of Biomedical Technology, University of Tampere, Tampere, Finland.; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
Levi-Schaffer F; Pharmacology Unit, School of Pharmacy, Faculty of Medicine, The Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.
Soumelis V; Institut Curie, Paris, France.; INSERM, Paris, France.
Schröder JM; Department of Dermatology, University Hospital Schleswig-Holstein, Kiel, Germany.
Kere J; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; School of Basic and Medical Biosciences, King's College London, London, UK.
Nestle FO; Cutaneous Medicine Unit, St. John's Institute of Dermatology and Biomedical Research Centre, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Barker J; St John's Institute of Dermatology, Division of Genetics and Molecular Medicine, Faculty of Life Sciences and Medicine, Kings College London, London, UK.
Ranki A; Department of Dermatology, Allergology and Venereology, Inflammation Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Lauerma A; Department of Dermatology, Allergology and Venereology, Inflammation Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Homey B; Department of Dermatology, University Hospital Duesseldorf, Duesseldorf, Germany.
Andersson B; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Alenius H; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Human Microbiome Research Program, University of Helsinki, Helsinki, Finland.
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Źródło :
Allergy [Allergy] 2021 Apr; Vol. 76 (4), pp. 1173-1187. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dermatitis, Atopic*/genetics
Eczema*
Microbiota*
Humans ; Skin ; Staphylococcus aureus/genetics
Czasopismo naukowe
Tytuł :
Dissection of intercellular communication using the transcriptome-based framework ICELLNET.
Autorzy :
Noël F; Université de Paris, INSERM U976, Equipe labellisée par la Ligue Nationale contre le Cancer, F-75006 Paris, France.; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U932, Immunity and Cancer, PSL Research University, Paris, France.
Massenet-Regad L; Université de Paris, INSERM U976, Equipe labellisée par la Ligue Nationale contre le Cancer, F-75006 Paris, France.; Université Paris-Saclay, Saint Aubin, 91190, France.
Carmi-Levy I; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U932, Immunity and Cancer, PSL Research University, Paris, France.
Cappuccio A; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U932, Immunity and Cancer, PSL Research University, Paris, France.
Grandclaudon M; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U932, Immunity and Cancer, PSL Research University, Paris, France.
Trichot C; Université de Paris, INSERM U976, Equipe labellisée par la Ligue Nationale contre le Cancer, F-75006 Paris, France.; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U932, Immunity and Cancer, PSL Research University, Paris, France.
Kieffer Y; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U830, Stress and Cancer Laboratory, Equipe labellisée par la Ligue Nationale contre le Cancer, PSL Research University, Paris, France.
Mechta-Grigoriou F; Institut Curie, 26 rue d'Ulm, Paris, France.; INSERM U830, Stress and Cancer Laboratory, Equipe labellisée par la Ligue Nationale contre le Cancer, PSL Research University, Paris, France.
Soumelis V; Université de Paris, INSERM U976, Equipe labellisée par la Ligue Nationale contre le Cancer, F-75006 Paris, France. vassili.soumelis@aphp.fr.; Institut Curie, 26 rue d'Ulm, Paris, France. vassili.soumelis@aphp.fr.; INSERM U932, Immunity and Cancer, PSL Research University, Paris, France. vassili.soumelis@aphp.fr.; AP-HP, Hôpital Saint-Louis, Département d'Immunologie-Histocompatibilité, Paris, 75010, France. vassili.soumelis@aphp.fr.
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Źródło :
Nature communications [Nat Commun] 2021 Feb 17; Vol. 12 (1), pp. 1089. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Databases, Factual*
Cell Communication/*genetics
Computational Biology/*methods
Gene Expression Profiling/*methods
Transcriptome/*genetics
Animals ; Cells, Cultured ; Dendritic Cells/cytology ; Dendritic Cells/metabolism ; Humans ; Keratinocytes/cytology ; Keratinocytes/metabolism ; Neutrophils/cytology ; Neutrophils/metabolism ; Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Clustering with missing and left-censored data: A simulation study comparing multiple-imputation-based procedures.
Autorzy :
Faucheux L; Université de Paris, Sorbonne Paris Cité, ECSTRRA Team, INSERM UMR1153, Paris, France.; Université de Paris, Sorbonne Paris Cité, INSERM U976, Paris, France.
Resche-Rigon M; Université de Paris, Sorbonne Paris Cité, ECSTRRA Team, INSERM UMR1153, Paris, France.; Service de Biostatistique et Information Médicale, AP-HP, Hôpital Saint-Louis, Paris, France.
Curis E; Service de Biostatistique et Information Médicale, AP-HP, Hôpital Saint-Louis, Paris, France.; Laboratoire de biomathématiques - plateau iB2 EA 7537 BioSTM, Faculté de Pharmacie, Université de Paris, Sorbonne Paris Cité, Paris, France.
Soumelis V; Université de Paris, Sorbonne Paris Cité, INSERM U976, Paris, France.; Laboratoire d'immunologie, biologie et histocompatibilité, AP-HP, Hôpital Saint-Louis, Paris, France.
Chevret S; Université de Paris, Sorbonne Paris Cité, ECSTRRA Team, INSERM UMR1153, Paris, France.; Service de Biostatistique et Information Médicale, AP-HP, Hôpital Saint-Louis, Paris, France.
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Źródło :
Biometrical journal. Biometrische Zeitschrift [Biom J] 2021 Feb; Vol. 63 (2), pp. 372-393. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
T H cell diversity and response to dupilumab in patients with atopic dermatitis.
Autorzy :
Trichot C; Institut Curie, PSL University, INSERM U932, Paris, France; Université de Paris, INSERM U976, Human Systemic Immunology and Inflammatory Network Team, Paris, France.
Faucheux L; Université de Paris, INSERM U976, Human Systemic Immunology and Inflammatory Network Team, Paris, France; Université de Paris, INSERM UMR-1153, ECSTRRA Team, Paris, France.
Karpf L; Institut Curie, PSL University, INSERM U932, Paris, France; Université de Paris, INSERM U976, Human Systemic Immunology and Inflammatory Network Team, Paris, France.
Grandclaudon M; Institut Curie, PSL University, INSERM U932, Paris, France.
Pattarini L; Institut Curie, PSL University, INSERM U932, Paris, France.
Bagot M; Université de Paris, INSERM U976, Skin Immunity and Inflammation Team, Paris, France; APHP, Dermatology Department, Hôpital Saint-Louis, Paris, France.
Mahévas T; Université de Paris, INSERM U976, Skin Immunity and Inflammation Team, Paris, France; APHP, Dermatology Department, Hôpital Saint-Louis, Paris, France.
Jachiet M; Université de Paris, INSERM U976, Skin Immunity and Inflammation Team, Paris, France; APHP, Dermatology Department, Hôpital Saint-Louis, Paris, France.
Saussine A; Université de Paris, INSERM U976, Skin Immunity and Inflammation Team, Paris, France; APHP, Dermatology Department, Hôpital Saint-Louis, Paris, France.
Bouaziz JD; Université de Paris, INSERM U976, Skin Immunity and Inflammation Team, Paris, France; APHP, Dermatology Department, Hôpital Saint-Louis, Paris, France.
Soumelis V; Institut Curie, PSL University, INSERM U932, Paris, France; Université de Paris, INSERM U976, Human Systemic Immunology and Inflammatory Network Team, Paris, France. Electronic address: vassili.soumelis@aphp.fr.
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Feb; Vol. 147 (2), pp. 756-759. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Humanized/*therapeutic use
Dermatitis, Atopic/*drug therapy
Dermatitis, Atopic/*immunology
T-Lymphocytes, Helper-Inducer/*drug effects
T-Lymphocytes, Helper-Inducer/*immunology
Humans ; T-Lymphocyte Subsets/drug effects ; T-Lymphocyte Subsets/immunology
Czasopismo naukowe
Tytuł :
SARS-CoV-2 induces human plasmacytoid pre-dendritic cell diversification via UNC93B and IRAK4.
Autorzy :
Onodi F; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, 75010 Paris, France.
Bonnet-Madin L; Université de Paris, Institut de Recherche Saint-Louis, INSERM U944 CNRS 7212, Hôpital Saint-Louis, 75010 Paris, France.
Meertens L; Université de Paris, Institut de Recherche Saint-Louis, INSERM U944 CNRS 7212, Hôpital Saint-Louis, 75010 Paris, France.
Karpf L; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, 75010 Paris, France.
Poirot J; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, 75010 Paris, France.
Zhang SY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France, EU.; Université de Paris; INSERM UMR 1163 Institut Imagine, France EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Picard C; Université de Paris; INSERM UMR 1163 Institut Imagine, France EU.; Study center for primary immunodeficiencies, Necker Hospital for Sick Children Assistance Publique-Hôpitaux (AP-HP) de Paris, Paris, France, EU.; Pediatric Hematology and Immunology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France, EU.
Puel A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France, EU.; Université de Paris; INSERM UMR 1163 Institut Imagine, France EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Jouanguy E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France, EU.; Université de Paris; INSERM UMR 1163 Institut Imagine, France EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Zhang Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Le Goff J; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, 75010 Paris, France.; Laboratoire de Virologie et Département des Maladies Infectieuses, Hôpital Saint-Louis, APHP, 75010 Paris, France.
Molina JM; Université de Paris, Institut de Recherche Saint-Louis, INSERM U944 CNRS 7212, Hôpital Saint-Louis, 75010 Paris, France.; Laboratoire de Virologie et Département des Maladies Infectieuses, Hôpital Saint-Louis, APHP, 75010 Paris, France.
Delaugerre C; Université de Paris, Institut de Recherche Saint-Louis, INSERM U944 CNRS 7212, Hôpital Saint-Louis, 75010 Paris, France.; Laboratoire de Virologie et Département des Maladies Infectieuses, Hôpital Saint-Louis, APHP, 75010 Paris, France.
Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France, EU.; Université de Paris; INSERM UMR 1163 Institut Imagine, France EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Pediatric Hematology and Immunology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France, EU.; Howard Hughes Medical Institute, New York, NY, USA.
Amara A; Université de Paris, Institut de Recherche Saint-Louis, INSERM U944 CNRS 7212, Hôpital Saint-Louis, 75010 Paris, France.
Soumelis V; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, 75010 Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, Laboratoire d'Immunologie, F-75010, Paris, France.
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Źródło :
BioRxiv : the preprint server for biology [bioRxiv] 2021 Jan 08. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Preprint
Tytuł :
Publisher Correction: The discovery of human TSLP as a critical epithelial cytokine in type 2 immunity and allergic disease.
Autorzy :
Soumelis V; HIPI Unit, Inserm U976, Institut de Recherche Saint-Louis, Université de Paris, Paris, France. vassili.soumelis@aphp.fr.; Laboratoire d'Immunologie et Histocompatibilité, AP-HP, Hôpital St Louis, Paris, France. vassili.soumelis@aphp.fr.
Liu YJ; Sanofi R&D, Cambridge, MA, USA. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Dec; Vol. 21 (12), pp. 1611.
Typ publikacji :
Published Erratum
Tytuł :
Deciphering the combinatorial landscape of immunity.
Autorzy :
Cappuccio A; Institut Curie, Integrative Biology of Human Dendritic Cells and T Cells Laboratory, PSL Research University, Inserm, U932, Paris, France.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, United States.
Jensen ST; Department of Statistics, Wharton School, University of Pennsylvania, Philadelphia, United States.
Hartmann BM; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, United States.
Sealfon SC; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, United States.
Soumelis V; Institut Curie, Integrative Biology of Human Dendritic Cells and T Cells Laboratory, PSL Research University, Inserm, U932, Paris, France.; Laboratoire d'immunologie, biologie et histocompatibilité, AP-HP, Hôpital Saint-Louis, Paris, France.
Zaslavsky E; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, United States.
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Źródło :
ELife [Elife] 2020 Nov 23; Vol. 9. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity/*physiology
Animals ; Databases as Topic ; Dendritic Cells/drug effects ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immunity/drug effects ; Immunity/immunology ; Immunologic Factors/pharmacology ; Interferon-beta/metabolism ; Interleukins/metabolism ; Machine Learning ; Mice ; Software ; T-Lymphocytes/drug effects ; T-Lymphocytes/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
Autorzy :
Zhang Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Liu Z; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Le Pen J; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Moncada-Velez M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Chen J; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Ogishi M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Sabli IKD; Department of Paediatric Infectious Diseases & Virology, Imperial College London, London, UK.
Hodeib S; Department of Paediatric Infectious Diseases & Virology, Imperial College London, London, UK.
Korol C; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.
Rosain J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Bilguvar K; Yale Center for Genome Analysis and Department of Genetics, Yale School of Medicine, New Haven, CT, USA.
Ye J; Zukerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Bolze A; Helix, San Mateo, CA, USA.
Bigio B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Yang R; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Arias AA; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Primary Immunodeficiencies Group, University of Antioquia UdeA, Medellin, Colombia.; School of Microbiology, University of Antioquia UdeA, Medellin, Colombia.
Zhou Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Zhang Y; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Bethesda, MD, USA.
Onodi F; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, Paris, France.
Korniotis S; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, Paris, France.
Karpf L; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, Paris, France.
Philippot Q; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Chbihi M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Bonnet-Madin L; Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR 7212, Université de Paris, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Paris, France.
Dorgham K; Sorbonne Université, Inserm, Centre d'Immunologie et des Maladies Infectieuses-Paris (CIMI PARIS), Assistance Publique-Hôpitaux de Paris (AP-HP) Hôpital Pitié-Salpêtrière, Paris, France.
Smith N; Translational Immunology Lab, Institut Pasteur, Paris, France.
Schneider WM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Razooky BS; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Hoffmann HH; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Michailidis E; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Moens L; Laboratory for Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Han JE; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Lorenzo L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Bizien L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Meade P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Neehus AL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Ugurbil AC; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Corneau A; Sorbonne Université, UMS037, PASS, Plateforme de Cytométrie de la Pitié-Salpêtrière CyPS, Paris, France.
Kerner G; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Zhang P; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Rapaport F; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Seeleuthner Y; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Manry J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Masson C; Bioinformatics Platform, Structure Fédérative de Recherche Necker, INSERM UMR1163, Université de Paris, Imagine Institute, Paris, France.
Schmitt Y; Bioinformatics Platform, Structure Fédérative de Recherche Necker, INSERM UMR1163, Université de Paris, Imagine Institute, Paris, France.
Schlüter A; Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran i Reynals, CIBERER U759, and Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.
Le Voyer T; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Khan T; Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar.
Li J; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Fellay J; School of Life sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Swiss Institue of Bioinformatics, Lausanne, Switzerland.
Roussel L; Infectious Disease Susceptibility Program, Research Institute, McGill University Health Centre, Montréal, Québec, Canada.
Shahrooei M; Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz, Iran.; Department of Microbiology and Immunology, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.
Alosaimi MF; Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Mansouri D; Department of Clinical Immunology and Infectious Diseases, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; The Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of, Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti, University of Medical Sciences, Tehran, Iran.; Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti, Iran.
Al-Saud H; National Center of Genomics Technology, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Al-Mulla F; Dasman Diabetes Institute, Department of Genetics and Bioinformatics, Kuwait.
Almourfi F; National Center of Genomics Technology, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Al-Muhsen SZ; Immunology Research Laboratory, Department of Pediatrics, College of Medicine and King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
Alsohime F; Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Al Turki S; Translational Pathology, Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Misery of National Guard Health Affairs, Riyadh, Saudi Arabia.; Cancer & Blood Research, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Hasanato R; Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
van de Beek D; Amsterdam UMC, Department of Neurology, Amsterdam Neuroscience, Amsterdam, Netherlands.
Biondi A; Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo, Monza, Italy.
Bettini LR; Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo, Monza, Italy.
D'Angio' M; Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo, Monza, Italy.
Bonfanti P; Department of Infectious Diseases, San Gerardo Hospital-University of Milano-Bicocca, Monza, Italy.
Imberti L; CREA Laboratory, Diagnostic Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Sottini A; CREA Laboratory, Diagnostic Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Paghera S; CREA Laboratory, Diagnostic Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy.
Quiros-Roldan E; Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali di Brescia, Brescia, Italy.
Rossi C; Chief Medical Officer, ASST Spedali Civili di Brescia, Brescia, Italy.
Oler AJ; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, MD, USA.
Tompkins MF; PRIMER, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Alba C; PRIMER, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Vandernoot I; Center of Human Genetics, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Goffard JC; Department of Internal Medicine, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Smits G; Center of Human Genetics, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Migeotte I; Fonds de la Recherche Scientifique (FNRS) and Center of Human Genetics, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Haerynck F; Department of Paediatric Immunology and Pulmonology, Centre for Primary Immunodeficiency Ghent (CPIG), PID Research Lab, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Ghent, Belgium.
Soler-Palacin P; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain.
Martin-Nalda A; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain.
Colobran R; Immunology Division, Genetics Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, UAB, Barcelona, Catalonia, Spain.
Morange PE; Aix Marseille Univ, INSERM, INRAE, C2VN, CHU Timone, Marseille, France.
Keles S; Necmettin Erbakan University, Meram Medical Faculty, Division of Pediatric Allergy and Immunology, Konya, Turkey.
Çölkesen F; Department of Infectious Diseases and Clinical Microbiology, Konya Training and Research Hospital, Konya, Turkey.
Ozcelik T; Department of Molecular Biology and Genetics, Bilkent University, Bilkent-Ankara, Turkey.
Yasar KK; Departments of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Senoglu S; Departments of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Karabela ŞN; Departments of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Rodríguez-Gallego C; Department of Immunology, Hospital Universitario de G.C. Dr. Negrín, Canarian Health System, Las Palmas de Gran Canaria, Spain.; University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.
Novelli G; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata,' Rome, Italy.
Hraiech S; Intensive Care Unit, AP-HM, Marseille, France.
Tandjaoui-Lambiotte Y; Avicenne Hospital Intensive Care Unit, APHP, Bobigny, INSERM U1272 Hypoxia & Lung, Paris, France.; PH Réanimation CHU Avicenne, Bobigny, INSERM U1272 Hypoxie & Poumon, Paris, France.
Duval X; Université de Paris, IAME UMR-S 1137, INSERM, Paris, France.; Inserm CIC 1425, Paris, France.
Laouénan C; Université de Paris, IAME UMR-S 1137, INSERM, Paris, France.; Inserm CIC 1425, Paris, France.; AP-HP, Département Epidémiologie Biostatistiques et Recherche Clinique, Hôpital Bichat, Paris, France.
Snow AL; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Dalgard CL; PRIMER, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Milner JD; Division of Pediatric Allergy, Immunology and Rheumatology, Columbia University, New York, USA.
Vinh DC; Infectious Disease Susceptibility Program, Research Institute, McGill University Health Centre, Montréal, Québec, Canada.
Mogensen TH; Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Marr N; Department of Immunology, Research Branch, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.
Spaan AN; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Department of Medical Microbiology, Utrecht UMC, Utrecht, Netherlands.
Boisson B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Boisson-Dupuis S; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Bustamante J; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.; Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, Paris, France.
Puel A; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Ciancanelli MJ; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Turnstone Biologics, New York, NY, USA.
Meyts I; Laboratory for Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.; Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Maniatis T; Zukerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.; New York Genome Center, New York, NY, USA.
Soumelis V; Université de Paris, Institut de Recherche Saint-Louis, INSERM U976, Hôpital Saint-Louis, Paris, France.; AP-HP, Hôpital Saint-Louis, Laboratoire d'Immunologie, Paris, France.
Amara A; Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR 7212, Université de Paris, Institut de Recherche Saint-Louis, Hôpital Saint-Louis, Paris, France.
Nussenzweig M; Laboratory of Molecular Immunology, Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, New York, NY, USA.
García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Pujol A; Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran i Reynals, CIBERER U759, and Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.
Duffy D; Translational Immunology Lab, Institut Pasteur, Paris, France.
Lifton RP; Laboratory of Genetics and Genomics, The Rockefeller University, New York, NY, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.; Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT, USA.
Zhang SY; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Gorochov G; Sorbonne Université, Inserm, Centre d'Immunologie et des Maladies Infectieuses-Paris (CIMI PARIS), Assistance Publique-Hôpitaux de Paris (AP-HP) Hôpital Pitié-Salpêtrière, Paris, France.
Béziat V; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Jouanguy E; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Sancho-Shimizu V; Department of Paediatric Infectious Diseases & Virology, Imperial College London, London, UK.
Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Abel L; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Bethesda, MD, USA.
Cobat A; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.
Su HC; Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.; NIAID Clinical Genomics Program, NIH, Bethesda, MD, USA.
Casanova JL; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA. .; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.; University of Paris, Imagine Institute, Paris, France.; Howard Hughes Medical Institute, New York, NY, USA.; Pediatric Hematology and Immunology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
Pokaż więcej
Corporate Authors :
COVID-STORM Clinicians
COVID Clinicians
Imagine COVID Group
French COVID Cohort Study Group
CoV-Contact Cohort
Amsterdam UMC Covid-19 Biobank
COVID Human Genetic Effort
NIAID-USUHS/TAGC COVID Immunity Group
Źródło :
Science (New York, N.Y.) [Science] 2020 Oct 23; Vol. 370 (6515). Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Loss of Function Mutation*
Coronavirus Infections/*genetics
Coronavirus Infections/*immunology
Interferon Type I/*immunology
Pneumonia, Viral/*genetics
Pneumonia, Viral/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alleles ; Asymptomatic Infections ; Betacoronavirus ; COVID-19 ; Child ; Child, Preschool ; Female ; Genetic Loci ; Genetic Predisposition to Disease ; Humans ; Infant ; Interferon Regulatory Factor-7/deficiency ; Interferon Regulatory Factor-7/genetics ; Male ; Middle Aged ; Pandemics ; Receptor, Interferon alpha-beta/deficiency ; Receptor, Interferon alpha-beta/genetics ; SARS-CoV-2 ; Toll-Like Receptor 3/deficiency ; Toll-Like Receptor 3/genetics ; Young Adult
Czasopismo naukowe

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