Targeting cholesterol impairs cell invasion of all breast cancer types.
Autorzy:
Maja M; CELL Unit and PICT Imaging Platform, de Duve Institute, UCLouvain, 1200, Brussels, Belgium. Verfaillie M; CELL Unit and PICT Imaging Platform, de Duve Institute, UCLouvain, 1200, Brussels, Belgium. Van Der Smissen P; CELL Unit and PICT Imaging Platform, de Duve Institute, UCLouvain, 1200, Brussels, Belgium. Henriet P; CELL Unit and PICT Imaging Platform, de Duve Institute, UCLouvain, 1200, Brussels, Belgium. Pierreux CE; CELL Unit and PICT Imaging Platform, de Duve Institute, UCLouvain, 1200, Brussels, Belgium. SounniNE; Laboratory of Tumor and Development Biology, GIGA-Cancer, University of Liège, 4000, Liège, Belgium. Tyteca D; CELL Unit and PICT Imaging Platform, de Duve Institute, UCLouvain, 1200, Brussels, Belgium. .
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Cancer cell international [Cancer Cell Int] 2024 Jan 10; Vol. 24 (1), pp. 27. Date of Electronic Publication: 2024 Jan 10.
Molecular Mechanisms Driven by MT4-MMP in Cancer Progression.
Autorzy:
Muñoz-Sáez E; Department of Health Science, School of Biomedical Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain. Moracho N; Department of Medicine, School of Biomedical Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain. Learte AIR; Department of Dentistry, School of Biomedical Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain. Collignon A; Laboratory of Biology of Tumor and Developmental Biology, GIGA Cancer, Liège University, B-4000 Liège, Belgium.; Cancer Metabolism and Tumor Microenvironment Group, GIGA Cancer, Liège University, B-4000 Liège, Belgium. Arroyo AG; Department of Molecular Biomedicine, Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC), 28040 Madrid, Spain. Noel A; Laboratory of Biology of Tumor and Developmental Biology, GIGA Cancer, Liège University, B-4000 Liège, Belgium. SounniNE; Laboratory of Biology of Tumor and Developmental Biology, GIGA Cancer, Liège University, B-4000 Liège, Belgium.; Cancer Metabolism and Tumor Microenvironment Group, GIGA Cancer, Liège University, B-4000 Liège, Belgium. Sánchez-Camacho C; Department of Genetics, Physiology and Microbiology, Faculty of Biological Sciences, Complutense University of Madrid, 28040 Madrid, Spain.
Lipid Metabolism Heterogeneity and Crosstalk with Mitochondria Functions Drive Breast Cancer Progression and Drug Resistance.
Autorzy:
Azam A; Cancer Metabolism and Tumor Microenvironment Group, GIGA-Cancer, University of Liège, 4000 Liège, Belgium.; Laboratory of Tumor and Development Biology, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. SounniNE; Cancer Metabolism and Tumor Microenvironment Group, GIGA-Cancer, University of Liège, 4000 Liège, Belgium.; Laboratory of Tumor and Development Biology, GIGA-Cancer, University of Liège, 4000 Liège, Belgium.
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Źródło:
Cancers [Cancers (Basel)] 2022 Dec 19; Vol. 14 (24). Date of Electronic Publication: 2022 Dec 19.
Estetrol Combined to Progestogen for Menopause or Contraception Indication Is Neutral on Breast Cancer.
Autorzy:
Gallez A; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Blacher S; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Maquoi E; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Konradowski E; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Joiret M; Biomechanics Research Unit, GIGA-In Silico Medicine, University of Liège, 4000 Liège, Belgium. Primac I; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Gérard C; Mithra Pharmaceuticals, rue Saint-Georges 5/7, 4000 Liège, Belgium. Taziaux M; Mithra Pharmaceuticals, rue Saint-Georges 5/7, 4000 Liège, Belgium. Houtman R; Precision Medicine Lab, 5349 AB Oss, The Netherlands. Geris L; Biomechanics Research Unit, GIGA-In Silico Medicine, University of Liège, 4000 Liège, Belgium. Lenfant F; INSERM U1048, Institut des Maladies Métaboliques et Cardiovasculaires, University Paul Sabatier, 31432 Toulouse, France. Marangoni E; Translational Research Department, Institute Curie, PSL Research University, 75248 Paris, France. SounniNE; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Foidart JM; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Noël A; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Péqueux C; Laboratory of Biology, Tumors and Development, GIGA-Cancer, University of Liège, 4000 Liège, Belgium.
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Cancers [Cancers (Basel)] 2021 May 20; Vol. 13 (10). Date of Electronic Publication: 2021 May 20.
Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy.
Autorzy:
Pottier C; Laboratory of Tumor and Development Biology, GIGA-Cancer and GIGA-I3, GIGA-Research, University Hospital of Liège, 4000 Liège, Belgium.; Department of Medical Oncology, University Hospital of Liège, 4000 Liège, Belgium. Fresnais M; Department of Clinical Pharmacology and Pharmacoepidemiology, University Hospital of Heidelberg, 69120 Heidelberg, Germany.; German Cancer Consortium (DKTK)-German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Gilon M; Laboratory of Tumor and Development Biology, GIGA-Cancer and GIGA-I3, GIGA-Research, University Hospital of Liège, 4000 Liège, Belgium. Jérusalem G; Department of Medical Oncology, University Hospital of Liège, 4000 Liège, Belgium. Longuespée R; Department of Clinical Pharmacology and Pharmacoepidemiology, University Hospital of Heidelberg, 69120 Heidelberg, Germany. SounniNE; Laboratory of Tumor and Development Biology, GIGA-Cancer and GIGA-I3, GIGA-Research, University Hospital of Liège, 4000 Liège, Belgium.
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Cancers [Cancers (Basel)] 2020 Mar 20; Vol. 12 (3). Date of Electronic Publication: 2020 Mar 20.
Rewiring of Lipid Metabolism and Storage in Ovarian Cancer Cells after Anti-VEGF Therapy.
Autorzy:
Curtarello M; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Tognon M; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Venturoli C; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Silic-Benussi M; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Grassi A; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Verza M; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Minuzzo S; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35128 Padova, Italy. Pinazza M; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy. Brillo V; Department of Biology, University of Padova, 35128 Padova, Italy. Tosi G; Department of Biology, University of Padova, 35128 Padova, Italy. Ferrazza R; Department of Physics, University of Trento, Via Sommarive 14, 38123 Trento, Italy. Guella G; Department of Physics, University of Trento, Via Sommarive 14, 38123 Trento, Italy. Iorio E; Core Facilities, NMR and MRI Unit, Istituto Superiore di Sanità, 00161 Roma, Italy. Godfroid A; Laboratory of Tumor and Development Biology, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. SounniNE; Laboratory of Tumor and Development Biology, GIGA-Cancer, University of Liège, 4000 Liège, Belgium. Amadori A; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35128 Padova, Italy. Indraccolo S; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
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Cells [Cells] 2019 Dec 09; Vol. 8 (12). Date of Electronic Publication: 2019 Dec 09.
MT4-MMP: The GPI-Anchored Membrane-Type Matrix Metalloprotease with Multiple Functions in Diseases.
Autorzy:
Yip C; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège 4000, Belgium. . Foidart P; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège 4000, Belgium. . Noël A; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège 4000, Belgium. . SounniNE; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliqué-Cancer (GIGA-Cancer), University of Liège, Liège 4000, Belgium. .
Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner.
Autorzy:
Vandereyken M; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Jacques S; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Van Overmeire E; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.; Laboratory of Myeloid Cell Immunology, VIB inflammation research center, Ghent, Belgium. Amand M; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Rocks N; Laboratory of Tumour and Developmental Biology, GIGA-Cancer, University of Liège, Liège, Belgium. Delierneux C; Laboratory of Thrombosis and Haemostasis, GIGA-Cardiovascular Sciences Unit, University of Liège, Liège, Belgium. Singh P; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Singh M; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Ghuysen C; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Wathieu C; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Zurashvili T; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. SounniNE; Laboratory of Tumour and Developmental Biology, GIGA-Cancer, University of Liège, Liège, Belgium. Moutschen M; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium. Gilles C; Laboratory of Tumour and Developmental Biology, GIGA-Cancer, University of Liège, Liège, Belgium. Oury C; Laboratory of Thrombosis and Haemostasis, GIGA-Cardiovascular Sciences Unit, University of Liège, Liège, Belgium. Cataldo D; Laboratory of Tumour and Developmental Biology, GIGA-Cancer, University of Liège, Liège, Belgium. Van Ginderachter JA; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.; Laboratory of Myeloid Cell Immunology, VIB inflammation research center, Ghent, Belgium. Rahmouni S; Immunology and Infectious Disease Unit, GIGA-I3, University of Liège, Liège, Belgium.
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PloS one [PLoS One] 2017 Oct 11; Vol. 12 (10), pp. e0185786. Date of Electronic Publication: 2017 Oct 11 (Print Publication: 2017).
Dynamics of internalization and recycling of the prometastatic membrane type 4 matrix metalloproteinase (MT4-MMP) in breast cancer cells.
Autorzy:
Truong A; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium. Yip C; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium. Paye A; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium. Blacher S; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium. Munaut C; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium. Deroanne C; Laboratory of Connective Tissues Biology, GIGA-Cancer, University of Liège, Belgium. Noel A; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium. SounniNE; Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Cancer (GIGA-Cancer), University of Liège, Belgium.
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Źródło:
The FEBS journal [FEBS J] 2016 Feb; Vol. 283 (4), pp. 704-22. Date of Electronic Publication: 2016 Jan 04.
Towards lipidomics of low-abundant species for exploring tumor heterogeneity guided by high-resolution mass spectrometry imaging.
Autorzy:
Cimino J Calligaris D; Mass Spectrometry Laboratory, GIGA-R, Department of Chemistry, University of Liege, Liege 4000, Belgium. . Far J Debois D Blacher S SounniNE Noel A De Pauw E; Mass Spectrometry Laboratory, GIGA-R, Department of Chemistry, University of Liege, Liege 4000, Belgium. .
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