Autor: "Spahn CM" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA.
Autorzy:: Yamamoto H; 1] Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany. [2].
Unbehaun A; 1] Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany. [2].
Loerke J; Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany.
Behrmann E; Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany.
Collier M; Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany.
Bürger J; 1] Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany. [2] UltraStrukturNetzwerk, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Mielke T; 1] Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany. [2] UltraStrukturNetzwerk, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Spahn CM; Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin, Berlin, Germany.; Pokaż więcej
Źródło:: Nature structural & molecular biology [Nat Struct Mol Biol] 2014 Aug; Vol. 21 (8), pp. 721-7. Date of Electronic Publication: 2014 Jul 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Eukaryotic Initiation Factors/*chemistry
Hepacivirus/*genetics
RNA, Viral/*chemistry
Ribosome Subunits, Large, Eukaryotic/*chemistry
Ribosome Subunits, Small, Eukaryotic/*chemistry
Animals ; Cryoelectron Microscopy ; Fourier Analysis ; Guanylyl Imidodiphosphate/chemistry ; Models, Molecular ; Nucleic Acid Conformation ; Protein Binding ; Protein Structure, Quaternary ; Protein Structure, Tertiary ; RNA, Transfer, Met/chemistry ; Rabbits

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Skocz do pozycji: 2.

Tytuł:: EF-G and EF4: translocation and back-translocation on the bacterial ribosome.
Autorzy:: Yamamoto H; 1] Institut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. [2].
Qin Y; 1] Laboratory of noncoding RNA, Institute of Biophysics, Chinese Academy of Science; 15 Datun Road, Beijing 100101, China. [2].
Achenbach J; 1] NOXXON Pharma AG, Max-Dohrn-Strasse 8-10, 10589 Berlin, Germany. [2].
Li C; Laboratory of noncoding RNA, Institute of Biophysics, Chinese Academy of Science; 15 Datun Road, Beijing 100101, China.
Kijek J; Max Planck Institut für molekulare Genetik, Ihnestrasse 73, D-14195 Berlin, Germany.
Spahn CM; Institut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Nierhaus KH; 1] Institut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. [2] Max Planck Institut für molekulare Genetik, Ihnestrasse 73, D-14195 Berlin, Germany.; Pokaż więcej
Źródło:: Nature reviews. Microbiology [Nat Rev Microbiol] 2014 Feb; Vol. 12 (2), pp. 89-100. Date of Electronic Publication: 2013 Dec 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Bacterial Translocation*
Models, Molecular*
Bacteria/*genetics
GTP Phosphohydrolases/*metabolism
Peptide Elongation Factor G/*metabolism
Ribosomes/*physiology
Bacteria/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Bacterial Proteins/physiology ; Binding Sites ; GTP Phosphohydrolases/genetics ; Guanosine Triphosphate/metabolism ; Hydrolysis ; Peptide Elongation Factor G/genetics ; Protein Biosynthesis ; RNA, Messenger/metabolism ; RNA, Transfer/metabolism

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Skocz do pozycji: 3.

Tytuł:: The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
Autorzy:: Ramrath DJ; Institut für Medizinische Physik und Biophysik, Charite - Universitätsmedizin Berlin, Ziegelstrasse 5-9, 10117 Berlin, Germany.
Yamamoto H
Rother K
Wittek D
Pech M
Mielke T
Loerke J
Scheerer P
Ivanov P
Teraoka Y
Shpanchenko O
Nierhaus KH
Spahn CM; Pokaż więcej
Źródło:: Nature [Nature] 2012 May 06; Vol. 485 (7399), pp. 526-9. Date of Electronic Publication: 2012 May 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Biosynthesis*
Escherichia coli/*chemistry
Peptide Elongation Factor G/*metabolism
RNA, Bacterial/*chemistry
RNA, Bacterial/*metabolism
RNA-Binding Proteins/*metabolism
Ribosomes/*metabolism
Base Sequence ; Cryoelectron Microscopy ; Fusidic Acid/metabolism ; Ligands ; Models, Molecular ; Nucleic Acid Conformation ; Peptide Elongation Factor G/chemistry ; Peptide Elongation Factor G/ultrastructure ; Protein Binding ; Protein Conformation ; RNA, Bacterial/genetics ; RNA, Bacterial/ultrastructure ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/ultrastructure ; Ribosome Subunits/chemistry ; Ribosome Subunits/genetics ; Ribosome Subunits/metabolism ; Ribosome Subunits/ultrastructure ; Ribosomes/chemistry ; Ribosomes/genetics ; Ribosomes/ultrastructure

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Skocz do pozycji: 4.

Tytuł:: The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre.
Autorzy:: Fritsch J; Mikrobiologie, Institut für Biologie, Humboldt-Universität zu Berlin, Chausseestraße 117, 10115 Berlin, Germany.
Scheerer P
Frielingsdorf S
Kroschinsky S
Friedrich B
Lenz O
Spahn CM; Pokaż więcej
Źródło:: Nature [Nature] 2011 Oct 16; Vol. 479 (7372), pp. 249-52. Date of Electronic Publication: 2011 Oct 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cupriavidus necator/*enzymology
Hydrogenase/*chemistry
Iron/*chemistry
Iron-Sulfur Proteins/*chemistry
Oxygen/*metabolism
Sulfur/*chemistry
Catalytic Domain ; Cell Membrane/metabolism ; Crystallography, X-Ray ; Cysteine/metabolism ; Hydrogenase/metabolism ; Iron/analysis ; Iron-Sulfur Proteins/metabolism ; Models, Molecular ; Oxidation-Reduction ; Protein Multimerization ; Protein Structure, Quaternary ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Protons ; Sulfur/analysis ; Water/chemistry ; Water/metabolism

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Skocz do pozycji: 5.

Tytuł:: Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites.
Autorzy:: Ratje AH; Institut für Medizinische Physik und Biophysik, Charite - Universitätsmedizin Berlin, Ziegelstrasse 5-9, 10117-Berlin, Germany.
Loerke J
Mikolajka A
Brünner M
Hildebrand PW
Starosta AL
Dönhöfer A
Connell SR
Fucini P
Mielke T
Whitford PC
Onuchic JN
Yu Y
Sanbonmatsu KY
Hartmann RK
Penczek PA
Wilson DN
Spahn CM; Pokaż więcej
Źródło:: Nature [Nature] 2010 Dec 02; Vol. 468 (7324), pp. 713-6.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Movement*
RNA, Transfer/*metabolism
Ribosome Subunits, Small, Bacterial/*chemistry
Ribosome Subunits, Small, Bacterial/*metabolism
Binding Sites ; Cryoelectron Microscopy ; Crystallography, X-Ray ; Guanosine Diphosphate/chemistry ; Guanosine Diphosphate/metabolism ; Models, Molecular ; Peptide Elongation Factor G/chemistry ; Peptide Elongation Factor G/metabolism ; Protein Biosynthesis ; Protein Conformation ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; RNA, Transfer/chemistry ; RNA, Transfer/ultrastructure ; Ribosome Subunits, Small, Bacterial/ultrastructure ; Thermus thermophilus/chemistry

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Skocz do pozycji: 6.

Tytuł:: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.
Autorzy:: Connell SR; Institut für Medizinische Physik und Biophysik, Charite-Universitätsmedizin Berlin, Ziegelstrasse 5-9, 10117-Berlin, Germany.
Topf M
Qin Y
Wilson DN
Mielke T
Fucini P
Nierhaus KH
Spahn CM; Pokaż więcej
Źródło:: Nature structural & molecular biology [Nat Struct Mol Biol] 2008 Sep; Vol. 15 (9), pp. 910-5.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Escherichia coli Proteins/*chemistry
Escherichia coli Proteins/*metabolism
RNA, Bacterial/*chemistry
RNA, Bacterial/*metabolism
RNA, Transfer/*chemistry
RNA, Transfer/*metabolism
Ribosomes/*chemistry
Ribosomes/*metabolism
Transcriptional Elongation Factors/*chemistry
Transcriptional Elongation Factors/*metabolism
Biological Transport, Active ; Escherichia coli/metabolism ; Guanosine Triphosphate/metabolism ; Hydrolysis ; Macromolecular Substances ; Models, Molecular ; Peptide Initiation Factors

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Skocz do pozycji: 7.

Tytuł:: Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Autorzy:: Schüler M; Institut für Medizinische Physik und Biophysik, Charite-Universitätsmedizin Berlin, Ziegelstrasse 5-9, 10117-Berlin, Germany.
Connell SR
Lescoute A
Giesebrecht J
Dabrowski M
Schroeer B
Mielke T
Penczek PA
Westhof E
Spahn CM; Pokaż więcej
Źródło:: Nature structural & molecular biology [Nat Struct Mol Biol] 2006 Dec; Vol. 13 (12), pp. 1092-6. Date of Electronic Publication: 2006 Nov 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gryllidae/*virology
RNA Viruses/*genetics
RNA, Viral/*chemistry
RNA, Viral/*metabolism
Ribosomes/*chemistry
Ribosomes/*metabolism
Animals ; Base Sequence ; Cryoelectron Microscopy ; Models, Molecular ; Molecular Sequence Data ; Nucleic Acid Conformation ; Paralysis ; Protein Binding ; Protein Structure, Tertiary ; RNA, Viral/ultrastructure ; Ribosomal Proteins/chemistry ; Ribosomal Proteins/metabolism ; Ribosomes/ultrastructure ; Saccharomyces cerevisiae/chemistry ; Saccharomyces cerevisiae/metabolism ; Structural Homology, Protein

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Skocz do pozycji: 8.

Tytuł:: Structure of eEF3 and the mechanism of transfer RNA release from the E-site.
Autorzy:: Andersen CB; Centre for Structural Biology, Department of Molecular Biology, University of Aarhus, Gustav Wieds Vej 10C, DK-8000 Aarhus, Denmark.
Becker T
Blau M
Anand M
Halic M
Balar B
Mielke T
Boesen T
Pedersen JS
Spahn CM
Kinzy TG
Andersen GR
Beckmann R; Pokaż więcej
Źródło:: Nature [Nature] 2006 Oct 12; Vol. 443 (7112), pp. 663-8. Date of Electronic Publication: 2006 Aug 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Fungal Proteins/*chemistry
Fungal Proteins/*metabolism
Peptide Elongation Factors/*chemistry
Peptide Elongation Factors/*metabolism
RNA, Transfer/*metabolism
Saccharomyces cerevisiae/*chemistry
Adenosine Diphosphate/chemistry ; Adenosine Diphosphate/metabolism ; Adenosine Triphosphate/analogs & derivatives ; Adenosine Triphosphate/metabolism ; Binding Sites ; Cryoelectron Microscopy ; Crystallography, X-Ray ; Fungal Proteins/ultrastructure ; Gene Expression Regulation, Fungal ; Models, Biological ; Models, Molecular ; Peptide Elongation Factors/ultrastructure ; Protein Conformation ; Ribosomes/chemistry ; Ribosomes/metabolism ; Saccharomyces cerevisiae Proteins ; Structure-Activity Relationship

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Skocz do pozycji: 9.

Tytuł:: Localization and dynamic behavior of ribosomal protein L30e.
Autorzy:: Halic M; Institute of Biochemistry, Charité, University Medical School Berlin, Monbijoustrasse 2, 10117 Berlin, Germany.
Becker T
Frank J
Spahn CM
Beckmann R; Pokaż więcej
Źródło:: Nature structural & molecular biology [Nat Struct Mol Biol] 2005 May; Vol. 12 (5), pp. 467-8. Date of Electronic Publication: 2005 May 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cryoelectron Microscopy*
Ribosomal Proteins/*metabolism
Ribosomal Proteins/*ultrastructure
Amino Acid Sequence ; Models, Molecular ; Molecular Sequence Data ; Protein Structure, Quaternary ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Ribosomal Proteins/chemistry ; Triticum/chemistry

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Skocz do pozycji: 10.

Tytuł:: Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM.
Autorzy:: Sengupta J; Health Research, Inc., Wadsworth Center, New York State Department of Health, Empire State Plaza, Albany, New York 12201-0509, USA.
Nilsson J
Gursky R
Spahn CM
Nissen P
Frank J; Pokaż więcej
Źródło:: Nature structural & molecular biology [Nat Struct Mol Biol] 2004 Oct; Vol. 11 (10), pp. 957-62. Date of Electronic Publication: 2004 Aug 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Neoplasm Proteins/*metabolism
Ribosomes/*metabolism
Cryoelectron Microscopy ; GTP-Binding Proteins ; Models, Molecular ; Protein Binding ; Receptors for Activated C Kinase ; Receptors, Cell Surface