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    Wyświetlanie 1-8 z 8
    Tytuł:
    Proteomic analyses do not reveal subclinical inflammation in fatigued patients with clinically quiescent inflammatory bowel disease.
    Autorzy:
    Bourgonje AR; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Wichers SJ; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Hu S; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
    van Dullemen HM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Faber KN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Samsom JN; Division of Gastroenterology, Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands.
    Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. l.m.spekhorst@umcg.nl.; Department of Gastroenterology and Hepatology, Medisch Spectrum Twente, Enschede, The Netherlands. l.m.spekhorst@umcg.nl.
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    Źródło:
    Scientific reports [Sci Rep] 2022 Aug 26; Vol. 12 (1), pp. 14581. Date of Electronic Publication: 2022 Aug 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Inflammatory Bowel Diseases*
    Proteomics*
    C-Reactive Protein ; Chronic Disease ; Fatigue ; Humans ; Inflammation ; Quality of Life
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease.
    Autorzy:
    Bourgonje AR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
    Hu S; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
    Zhernakova DV; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.; Laboratory of Genomic Diversity, Center for Computer Technologies, ITMO University, St Petersburg, Russia.
    Vich Vila A; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
    Li Y; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
    Voskuil MD; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
    van Berkel LA; Department of Pediatrics, Division of Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands.
    Bley Folly B; Department of Pediatrics, Division of Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands.
    Charrout M; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands.
    Mahfouz A; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
    Reinders MJT; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands.
    van Heck JIP; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
    Joosten LAB; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
    Visschedijk MC; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
    van Dullemen HM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
    Faber KN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
    Samsom JN; Department of Pediatrics, Division of Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands.
    Festen EAM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
    Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
    Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
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    Źródło:
    Journal of Crohn's & colitis [J Crohns Colitis] 2022 Mar 14; Vol. 16 (3), pp. 414-429.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Colitis, Ulcerative*/diagnosis
    Inflammatory Bowel Diseases*/genetics
    Case-Control Studies ; Genotype ; Humans ; Phenotype ; Proteome/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Polygenetic risk scores do not add predictive power to clinical models for response to anti-TNFα therapy in inflammatory bowel disease.
    Autorzy:
    Karmi N; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Bangma A; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    van Dullemen HM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Visschedijk MC; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Voskuil MD; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Festen EAM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
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    Źródło:
    PloS one [PLoS One] 2021 Sep 17; Vol. 16 (9), pp. e0256860. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Adalimumab/*therapeutic use
    Colitis, Ulcerative/*drug therapy
    Crohn Disease/*drug therapy
    Gastrointestinal Agents/*therapeutic use
    Immunologic Factors/*therapeutic use
    Infliximab/*therapeutic use
    Tumor Necrosis Factor-alpha/*antagonists & inhibitors
    Adult ; Colitis, Ulcerative/genetics ; Colitis, Ulcerative/immunology ; Colitis, Ulcerative/pathology ; Crohn Disease/genetics ; Crohn Disease/immunology ; Crohn Disease/pathology ; Female ; Gene Expression ; Humans ; Immunotherapy/methods ; Male ; Middle Aged ; Multifactorial Inheritance ; Remission Induction ; Retrospective Studies ; Treatment Outcome ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Correction to: The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1.
    Autorzy:
    Imhann F; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Van der Velde KJ; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Barbieri R; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Alberts R; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Voskuil MD; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Vila AV; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Collij V; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Van der Sloot KWJ; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Peters V; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Van Dullemen HM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Swertz MA; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands. .
    Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands. .
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    Źródło:
    BMC gastroenterology [BMC Gastroenterol] 2019 Mar 27; Vol. 19 (1), pp. 44. Date of Electronic Publication: 2019 Mar 27.
    Typ publikacji:
    Journal Article; Published Erratum
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1.
    Autorzy:
    Imhann F; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Van der Velde KJ; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Barbieri R; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Alberts R; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Voskuil MD; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Vich Vila A; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Collij V; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Van der Sloot KWJ; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Peters V; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Van Dullemen HM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.
    Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Swertz MA; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands.
    Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands. .
    Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, the Netherlands. .
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    Źródło:
    BMC gastroenterology [BMC Gastroenterol] 2019 Jan 08; Vol. 19 (1), pp. 5. Date of Electronic Publication: 2019 Jan 08.
    Typ publikacji:
    Dataset; Journal Article
    MeSH Terms:
    Inflammatory Bowel Diseases/*classification
    Inflammatory Bowel Diseases/*genetics
    Adolescent ; Adult ; Aged ; Biomarkers ; Biopsy ; Diet ; Environment ; Female ; Gastrointestinal Microbiome ; Genotype ; Humans ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/pathology ; Male ; Middle Aged ; Netherlands ; Phenotype ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, DNA ; Transcriptome ; Exome Sequencing ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease.
    Autorzy:
    Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Cheng SC; Broad Institute of Harvard and MIT, Boston, USA.
    van Loo ES; Department of Surgery, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Jansen BHD; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Blokzijl T; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Kil H; Department of Epigenetics and Molecular Carcinogenesis, Science Park, The University of Texas M.D. Anderson Cancer Centre, Smithville, USA.
    de Jong DJ; Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
    Pierik M; Division of Gastroenterology and Hepatology, University Medical Centre Maastricht, Maastricht, The Netherlands.
    Maljaars JPWJ; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.
    van der Woude CJ; Department of Gastroenterology and Hepatology, Erasmus Medical Centre, Rotterdam, The Netherlands.
    van Bodegraven AA; Department of Gastroenterology and Hepatology, VU University Medical Centre, Amsterdam, The Netherlands.
    Oldenburg B; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, The Netherlands.
    Löwenberg M; Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands.
    Nieuwenhuijs VB; Department of Surgery, Isala Clinics, Zwolle, The Netherlands.
    Imhann F; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    van Sommeren S; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Alberts R; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Xavier RJ; Broad Institute of Harvard and MIT, Boston, USA.
    Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Nico Faber K; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Aldaz CM; Department of Epigenetics and Molecular Carcinogenesis, Science Park, The University of Texas M.D. Anderson Cancer Centre, Smithville, USA.
    Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
    Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
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    Źródło:
    Journal of Crohn's & colitis [J Crohns Colitis] 2018 Apr 27; Vol. 12 (5), pp. 582-588.
    Typ publikacji:
    Journal Article; Meta-Analysis
    MeSH Terms:
    Crohn Disease/*genetics
    Crohn Disease/*metabolism
    RNA, Messenger/*metabolism
    Tumor Suppressor Proteins/*genetics
    WW Domain-Containing Oxidoreductase/*genetics
    Adolescent ; Adult ; Alleles ; Case-Control Studies ; Constriction, Pathologic/etiology ; Crohn Disease/complications ; Female ; Fibrosis ; Genome-Wide Association Study ; Genomics ; Humans ; Male ; Phenotype ; Polymorphism, Single Nucleotide ; RNA, Long Noncoding/genetics ; Transforming Growth Factor beta/genetics ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Impact of Ethnicity and Country of Birth on Inflammatory Bowel Disease Phenotype: a Prospective Cohort Study.
    Autorzy:
    Spekhorst LM; University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, The Netherlands.; University of Groningen and University Medical Center Groningen, Department of Genetics, The Netherlands.
    Severs M; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, The Netherlands.
    de Boer NKH; Department of Gastroenterology and Hepatology, VU University Medical Centre, The Netherlands.
    Festen EAM; University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, The Netherlands.; University of Groningen and University Medical Center Groningen, Department of Genetics, The Netherlands.
    Fidder HH; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, The Netherlands.
    Hoentjen F; Department of Gastroenterology and Hepatology, University Medical Centre St. Radboud, The Netherlands.
    Imhann F; University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, The Netherlands.; University of Groningen and University Medical Center Groningen, Department of Genetics, The Netherlands.
    de Jong DJ; Department of Gastroenterology and Hepatology, University Medical Centre St. Radboud, The Netherlands.
    van der Meulen-de Jong AE; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, The Netherlands.
    Pierik MJ; Department of Gastroenterology and Hepatology, University Medical Centre Maastricht, The Netherlands.
    van der Woude CJ; Department of Gastroenterology and Hepatology, Erasmus Medical Centre, The Netherlands.
    Dijkstra G; University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, The Netherlands.
    Ponsioen CY; Department of Gastroenterology and Hepatology, Amsterdam Medical Centre, The Netherlands.
    Löwenberg M; Department of Gastroenterology and Hepatology, Amsterdam Medical Centre, The Netherlands.
    Oldenburg B; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, The Netherlands.
    Weersma RK; University of Groningen and University Medical Center Groningen, Department of Gastroenterology and Hepatology, The Netherlands.
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    Corporate Authors:
    Parelsnoer Institute and the Dutch Initiative on Crohn and Colitis
    Źródło:
    Journal of Crohn's & colitis [J Crohns Colitis] 2017 Dec 04; Vol. 11 (12), pp. 1463-1470.
    Typ publikacji:
    Journal Article; Multicenter Study
    MeSH Terms:
    Phenotype*
    Residence Characteristics*
    Colitis, Ulcerative/*ethnology
    Crohn Disease/*ethnology
    Intestinal Fistula/*ethnology
    Adult ; Age of Onset ; Aged ; Anal Canal/pathology ; Colitis, Ulcerative/genetics ; Colitis, Ulcerative/therapy ; Constriction, Pathologic/ethnology ; Crohn Disease/genetics ; Crohn Disease/therapy ; Digestive System Surgical Procedures/statistics & numerical data ; Europe/ethnology ; Female ; Humans ; Male ; Middle Aged ; Netherlands/epidemiology ; Prospective Studies ; White People/statistics & numerical data
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2.
    Autorzy:
    Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, 9700 RB, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, 9700 RB, Groningen, The Netherlands.
    Alberts R; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, 9700 RB, Groningen, The Netherlands.
    Mucha S; Institute of Clinical Molecular Biology, Kiel University, D-24105, Kiel, Germany.
    Deelen P; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, 9700 RB, Groningen, The Netherlands.
    de Jong DJ; Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, 6525 GA, Nijmegen, The Netherlands.
    Pierik M; Division of Gastroenterology and Hepatology, Maastricht University Medical Centre, 6229 HX, Maastricht, The Netherlands.
    Spekhorst LM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, 9700 RB, Groningen, The Netherlands.
    Imhann F; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, 9700 RB, Groningen, The Netherlands.
    van der Meulen-de Jong AE; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, 2333 ZA, Leiden, The Netherlands.
    van der Woude CJ; Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, 3015 CE, Rotterdam, The Netherlands.
    van Bodegraven AA; Department of Gastroenterology and Hepatology, VU University Medical Centre, 1081 HZ, Amsterdam, The Netherlands.
    Oldenburg B; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, 3584 CX, Utrecht, The Netherlands.
    Löwenberg M; Department of Gastroenterology and Hepatology, Academic Medical Centre, 1105 AZ, Amsterdam, The Netherlands.
    Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, 9700 RB, Groningen, The Netherlands.
    Ellinghaus D; Institute of Clinical Molecular Biology, Kiel University, D-24105, Kiel, Germany.
    Schreiber S; Department of Internal Medicine I, University Medical Centre Schleswig-Holstein, Kiel, Germany.
    Wijmenga C; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, 9700 RB, Groningen, The Netherlands.
    Rivas MA; Centre for the Study of IBD (SCIBD) Genetics, The Broad Institute, Cambridge, Massachusetts, United States of America.
    Franke A; Institute of Clinical Molecular Biology, Kiel University, D-24105, Kiel, Germany.
    van Diemen CC; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, 9700 RB, Groningen, The Netherlands.
    Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, 9700 RB, Groningen, The Netherlands.
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    Corporate Authors:
    Initiative on Crohn and Colitis
    Parelsnoer Institute
    Źródło:
    PloS one [PLoS One] 2016 Aug 04; Vol. 11 (8), pp. e0159609. Date of Electronic Publication: 2016 Aug 04 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Colitis, Ulcerative/*genetics
    Mucin-2/*genetics
    Case-Control Studies ; Colitis, Ulcerative/pathology ; DNA/chemistry ; DNA/isolation & purification ; DNA/metabolism ; Gene Frequency ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Netherlands ; Polymorphism, Single Nucleotide ; Promoter Regions, Genetic ; Quantitative Trait Loci ; Sequence Analysis, DNA
    Czasopismo naukowe
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