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Tytuł:
Current and emerging treatment options for nasopharyngeal carcinoma
Autorzy:
Spratt DE
Lee N
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Temat:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
OncoTargets and Therapy, Vol 2012, Iss default, Pp 297-308 (2012)
Opis pliku:
electronic resource
Relacje:
http://www.dovepress.com/current-and-emerging-treatment-options-for-nasopharyngeal-carcinoma-a11325; https://doaj.org/toc/1178-6930
Dostęp URL:
https://doaj.org/article/40b6d306c43240f49a839be5582ac28d  Link otwiera się w nowym oknie
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways.
Autorzy:
Waters KL; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
Spratt DE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 30; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
DNA Repair*
DNA Damage*
Humans ; DNA End-Joining Repair ; Genomic Instability ; DNA
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prognostic Role of Dynamic Changes in Serological Markers in Metastatic Hormone Naïve Prostate Cancer.
Autorzy:
Roy S; Department of Radiation Oncology, Rush University Medical Center, Chicago, IL 60612, USA.; Department of Epidemiology, Usher Institute, The Edinburgh University, Edinburgh EH16 4SS, UK.
Sun Y; Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Wallis CJD; Department of Urology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON M5G 1X5, Canada.
Kishan AU; Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA 90095, USA.
Morgan SC; Division of Radiation Oncology, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Spratt DE; Department of Radiation Oncology, University Hospital Seidman Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA.
Malone S; Division of Radiation Oncology, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Saad F; Department of Surgery, Université de Montréal, Montreal, QC H2X 0A9, Canada.
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Źródło:
Cancers [Cancers (Basel)] 2023 Sep 02; Vol. 15 (17). Date of Electronic Publication: 2023 Sep 02.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of Intercalated Cell Markers KIT and LINC01187 in Chromophobe Renal Cell Carcinoma and Other Renal Neoplasms.
Autorzy:
Mannan R; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Wang X; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Bawa PS; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Zhang Y; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Skala SL; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Chinnaiyan AK; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Dagar A; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Wang L; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Zelenka-Wang SB; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
McMurry LM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Daniel N; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Cao X; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Howard Hughes Medical Institute, Ann Arbor, MI, USA.
Sangoi AR; Department of Pathology, El Camino Hospital, Mountain View, CA, USA.
Gupta S; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Vaishampayan UN; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Department of Hematology/Oncology, University of Michigan, Ann Arbor, MI, USA.
Hafez KS; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Morgan TM; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Spratt DE; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
Tretiakova MS; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Argani P; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA.
Chinnaiyan AM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Howard Hughes Medical Institute, Ann Arbor, MI, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Dhanasekaran SM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Mehra R; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.
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Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2023 Sep; Vol. 31 (6), pp. 1027-1040. Date of Electronic Publication: 2022 Oct 16.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/diagnosis
Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/pathology
Kidney Neoplasms*/diagnosis
Kidney Neoplasms*/genetics
Kidney Neoplasms*/pathology
Adenoma, Oxyphilic*/diagnosis
Adenoma, Oxyphilic*/pathology
Humans ; Follow-Up Studies ; Biomarkers, Tumor/metabolism ; RNA ; Diagnosis, Differential
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development and validation of a life expectancy calculator for US patients with prostate cancer.
Autorzy:
Chase EC; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
Bryant AK; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Sun Y; Department of Radiation Oncology, University Hospitals/Case Western Reserve University, Cleveland, OH, USA.
Jackson WC; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Spratt DE; Department of Radiation Oncology, University Hospitals/Case Western Reserve University, Cleveland, OH, USA.
Dess RT; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Schipper MJ; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
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Źródło:
BJU international [BJU Int] 2022 Oct; Vol. 130 (4), pp. 496-506. Date of Electronic Publication: 2022 Apr 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Prostatic Neoplasms*/therapy
Child ; Humans ; Life Expectancy ; Male ; Nutrition Surveys ; Prostate ; Prostate-Specific Antigen ; United States/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Leveraging artificial intelligence to predict ERG gene fusion status in prostate cancer.
Autorzy:
Dadhania V; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Gonzalez D; Department of Pathology and Laboratory Medicine, Jackson Memorial Hospital, Miami, FL, USA.
Yousif M; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA.
Cheng J; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Morgan TM; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Spratt DE; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Reichert ZR; Department of Medical Oncology, University of Michigan Medical School, Ann Arbor, MI, USA.
Mannan R; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Wang X; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Chinnaiyan A; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Cao X; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Dhanasekaran SM; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Chinnaiyan AM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Howard Hughes Medical Institute, Ann Arbor, MI, USA.
Pantanowitz L; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.
Mehra R; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA. .; Michigan Center for Translational Pathology, Ann Arbor, MI, USA. .; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA. .
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Źródło:
BMC cancer [BMC Cancer] 2022 May 05; Vol. 22 (1), pp. 494. Date of Electronic Publication: 2022 May 05.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/diagnosis
Adenocarcinoma*/genetics
Adenocarcinoma*/pathology
Prostatic Neoplasms*/pathology
Artificial Intelligence ; Gene Fusion ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Oncogene Proteins, Fusion/genetics ; Transcriptional Regulator ERG/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intersection of Redox Chemistry and Ubiquitylation: Post-Translational Modifications Required for Maintaining Cellular Homeostasis and Neuroprotection.
Autorzy:
Kane EI; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
Waters KL; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
Spratt DE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
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Źródło:
Cells [Cells] 2021 Aug 18; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Ubiquitination/*physiology
Animals ; Homeostasis/genetics ; Homeostasis/physiology ; Humans ; Neuroprotection/genetics ; Neuroprotection/physiology ; Oxidation-Reduction ; Protein Processing, Post-Translational/genetics ; Protein Processing, Post-Translational/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response.
Autorzy:
Mathieu NA; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
Paparisto E; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, 1151 Richmond St., London, ON N6A 5C1, Canada.
Barr SD; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, 1151 Richmond St., London, ON N6A 5C1, Canada.
Spratt DE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
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Źródło:
Viruses [Viruses] 2021 Jun 09; Vol. 13 (6). Date of Electronic Publication: 2021 Jun 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cytokines/*genetics
Interferons/*immunology
Intracellular Signaling Peptides and Proteins/*genetics
Ubiquitins/*genetics
Virus Diseases/*immunology
Animals ; COVID-19/immunology ; Cytokines/immunology ; HeLa Cells ; Humans ; Intracellular Signaling Peptides and Proteins/immunology ; Mice ; SARS-CoV-2/immunology ; Ubiquitins/immunology ; Viral Proteins/genetics ; Viral Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences.
Autorzy:
Rayford W; The Urology Group LLC, Memphis, TN, USA.
Beksac AT; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alger J; Department of Urology, Medstar Georgetown University Hospital, Washington, DC, USA.
Alshalalfa M; Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Ahmed M; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Khan I; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Falagario UG; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Liu Y; Decipher Biosciences, San Diego, CA, USA.
Davicioni E; Decipher Biosciences, San Diego, CA, USA.
Spratt DE; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Schaeffer EM; Department of Urology, Northwestern University, Chicago, IL, USA.
Feng FY; Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Mahal B; Department of Radiation Oncology, Brigham and Women's Hospital, Boston, MA, USA.
Nguyen PL; Department of Radiation Oncology, Brigham and Women's Hospital, Boston, MA, USA.
Den RB; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA.
Greenberger MD; The Urology Group LLC, Memphis, TN, USA.
Bradley R; Haslam College of Business, University of Tennessee, Knoxville, TN, USA.
Watson JM; WellStar Urology, Marietta, GA, USA.
Beamer M; Department of Urology, Medstar Georgetown University Hospital, Washington, DC, USA.
Stamatakis L; Department of Urology, Medstar Georgetown University Hospital, Washington, DC, USA.
Carmen DJ; Georgia Urology, Atlanta, GA, USA.
Awasthi S; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Hwang J; Department of Urology, Medstar Georgetown University Hospital, Washington, DC, USA.
Weil R; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Merisaari H; Department of Clinical Medicine, University of Turku, Turku, Finland.
Mohamed N; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Deane LA; Department of Urology, Rush University Medical Center, Chicago, IL, USA.
Chakravarty D; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Yadav KK; Sema4, a Mount Sinai venture, Stamford, CT, USA.
Yamoah K; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Nair SS; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Tewari AK; Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .
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Źródło:
Communications biology [Commun Biol] 2021 Jun 03; Vol. 4 (1), pp. 670. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji:
Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Black or African American/*genetics
Gene Expression Profiling/*methods
Genomics/*methods
Prostatic Neoplasms/*genetics
White People/*genetics
Black or African American/statistics & numerical data ; Aged ; Health Status Disparities ; Humans ; Immune System/immunology ; Immune System/metabolism ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Prostatic Neoplasms/ethnology ; Prostatic Neoplasms/immunology ; Retrospective Studies ; United States ; White People/statistics & numerical data
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural Insights into Ankyrin Repeat-Containing Proteins and Their Influence in Ubiquitylation.
Autorzy:
Kane EI; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
Spratt DE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, 950 Main St., Worcester, MA 01610, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 09; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Ankyrin Repeat*
Ubiquitination*
Animals ; Carcinogenesis/metabolism ; Endopeptidases/chemistry ; Endopeptidases/metabolism ; Humans ; Models, Molecular ; Proteasome Endopeptidase Complex/chemistry ; Proteasome Endopeptidase Complex/metabolism ; Proto-Oncogene Proteins/chemistry ; Proto-Oncogene Proteins/metabolism ; Signal Transduction ; Ubiquitin/chemistry ; Ubiquitin/metabolism ; Ubiquitin Thiolesterase/chemistry ; Ubiquitin Thiolesterase/metabolism ; Ubiquitin-Protein Ligases/chemistry ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity.
Autorzy:
Beasley SA; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, Worcester, MA, United States of America.
Kellum CE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, Worcester, MA, United States of America.
Orlomoski RJ; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, Worcester, MA, United States of America.
Idrizi F; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, Worcester, MA, United States of America.
Spratt DE; Gustaf H. Carlson School of Chemistry and Biochemistry, Clark University, Worcester, MA, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Jul 08; Vol. 15 (7), pp. e0235925. Date of Electronic Publication: 2020 Jul 08 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Angelman Syndrome/*genetics
Ubiquitin-Protein Ligases/*metabolism
Angelman Syndrome/pathology ; Biocatalysis ; Circular Dichroism ; Humans ; Mutagenesis, Site-Directed ; Nuclear Magnetic Resonance, Biomolecular ; Protein Domains ; Protein Stability ; Protein Structure, Secondary ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Ubiquitin/metabolism ; Ubiquitin-Protein Ligases/chemistry ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tumor Immune Microenvironment Clusters in Localized Prostate Adenocarcinoma: Prognostic Impact of Macrophage Enriched/Plasma Cell Non-Enriched Subtypes.
Autorzy:
Jairath NK; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Farha MW; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Srinivasan S; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Jairath R; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Green MD; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.; Veterans Affair Ann Arbor Healthcare System, University of Michigan, Ann Arbor, MI 48104, USA.
Dess RT; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Jackson WC; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Weiner AB; Department of Urology, Northwestern University, Chicago, IL 60611, USA.
Schaeffer EM; Department of Urology, Northwestern University, Chicago, IL 60611, USA.
Zhao SG; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Feng FY; Department of Radiation Oncology, UCSF, San Francisco, CA 94143, USA.
El Naqa I; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
Spratt DE; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48104, USA.
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Źródło:
Journal of clinical medicine [J Clin Med] 2020 Jun 24; Vol. 9 (6). Date of Electronic Publication: 2020 Jun 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Applications of Molecular Biomarkers in Prostate Cancer.
Autorzy:
Couñago F; Radiation Oncology, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.; Radiation Oncology, Hospital La Luz, 28003 Madrid, Spain.; Clinical Department, Faculty of Biomedicine. Universidad Europea de Madrid, 28670 Madrid, Spain.
López-Campos F; Radiation Oncology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Díaz-Gavela AA; Radiation Oncology, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.; Radiation Oncology, Hospital La Luz, 28003 Madrid, Spain.; Clinical Department, Faculty of Biomedicine. Universidad Europea de Madrid, 28670 Madrid, Spain.
Almagro E; Medical Oncology, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.
Fenández-Pascual E; Lyx Institute of Urology, Universidad Francisco de Vitoria, 28006 Madrid, Spain.; Department of Urology, Hospital Universitario La Paz, 28046 Madrid, Spain.
Henríquez I; Radiation Oncology, Hospital Universitario Sant Joan, 43204 Reus, Spain.
Lozano R; Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre, 28029 Madrid, Spain.; Genitourinary Cancer Traslational Research Group, Institute of Biomedical Research, 29010 Málaga, Spain.
Linares Espinós E; Lyx Institute of Urology, Universidad Francisco de Vitoria, 28006 Madrid, Spain.; Department of Urology, Hospital Universitario La Paz, 28046 Madrid, Spain.
Gómez-Iturriaga A; Cruces University Hospital, Biocruces Heath Research Institute, 48903 Barakaldo, Spain.
de Velasco G; Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
Quintana Franco LM; Department of Urology, Hospital Universitario La Paz, 28046 Madrid, Spain.
Rodríguez-Melcón I; Radiation Oncology, Hospital Universitario de Gran Canaria Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain.
López-Torrecilla J; Radiation Oncology-ERESA, Hospital General Universitario de Valencia, 46014 Valencia, Spain.
Spratt DE; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA.
Guerrero LL; Radiation Oncology, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.; Radiation Oncology, Hospital La Luz, 28003 Madrid, Spain.; Clinical Department, Faculty of Biomedicine. Universidad Europea de Madrid, 28670 Madrid, Spain.
Martínez-Salamanca JI; Lyx Institute of Urology, Universidad Francisco de Vitoria, 28006 Madrid, Spain.; Department of Urology, Hospital Universitario Puerta de Hierro, 28222 Madrid, Spain.
Del Cerro E; Radiation Oncology, Hospital Universitario Quirónsalud Madrid, 28223 Madrid, Spain.; Radiation Oncology, Hospital La Luz, 28003 Madrid, Spain.; Clinical Department, Faculty of Biomedicine. Universidad Europea de Madrid, 28670 Madrid, Spain.
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Źródło:
Cancers [Cancers (Basel)] 2020 Jun 12; Vol. 12 (6). Date of Electronic Publication: 2020 Jun 12.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clinicopathological characterisation of renal cell carcinoma in young adults: a contemporary update and review of literature.
Autorzy:
Abdulfatah E; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Kennedy JM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Hafez K; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Davenport MS; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Radiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Xiao H; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Weizer AZ; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Palapattu GS; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Urology, Medical University of Vienna, Vienna, Austria.
Morgan TM; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Mannan R; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Wang XM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Dhanasekaran SM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.
Kaffenberger SD; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.
Spratt DE; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA.
Kunju L; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Wu A; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Lew M; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Udager AM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.
Chinnaiyan AM; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.; Howard Hughes Medical Institute, Ann Arbor, MI, USA.
Mehra R; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, Ann Arbor, MI, USA.; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.
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Źródło:
Histopathology [Histopathology] 2020 May; Vol. 76 (6), pp. 875-887. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinoma, Renal Cell/*pathology
Kidney Neoplasms/*pathology
Adolescent ; Adult ; Age of Onset ; Child ; Female ; Humans ; Male ; Young Adult
Czasopismo naukowe
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Tytuł:
Contemporary Renal Tumor Categorization With Biomarker and Translational Updates: A Practical Review.
Autorzy:
Taylor AS; From the Departments of Pathology (Drs Taylor, Dhanasekaran, and Mehra) and Radiation Oncology (Dr Spratt), University of Michigan Medical School, Ann Arbor; the Rogel Cancer Center, Michigan Medicine, Ann Arbor (Drs Spratt and Mehra); and the Michigan Center for Translational Pathology, Ann Arbor (Drs Dhanasekaran and Mehra).
Spratt DE; From the Departments of Pathology (Drs Taylor, Dhanasekaran, and Mehra) and Radiation Oncology (Dr Spratt), University of Michigan Medical School, Ann Arbor; the Rogel Cancer Center, Michigan Medicine, Ann Arbor (Drs Spratt and Mehra); and the Michigan Center for Translational Pathology, Ann Arbor (Drs Dhanasekaran and Mehra).
Dhanasekaran SM; From the Departments of Pathology (Drs Taylor, Dhanasekaran, and Mehra) and Radiation Oncology (Dr Spratt), University of Michigan Medical School, Ann Arbor; the Rogel Cancer Center, Michigan Medicine, Ann Arbor (Drs Spratt and Mehra); and the Michigan Center for Translational Pathology, Ann Arbor (Drs Dhanasekaran and Mehra).
Mehra R; From the Departments of Pathology (Drs Taylor, Dhanasekaran, and Mehra) and Radiation Oncology (Dr Spratt), University of Michigan Medical School, Ann Arbor; the Rogel Cancer Center, Michigan Medicine, Ann Arbor (Drs Spratt and Mehra); and the Michigan Center for Translational Pathology, Ann Arbor (Drs Dhanasekaran and Mehra).
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2019 Dec; Vol. 143 (12), pp. 1477-1491.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biomarkers, Tumor/*analysis
Kidney Neoplasms/*classification
Kidney Neoplasms/*diagnosis
Humans ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A phase II randomized placebo-controlled double-blind study of salvage radiation therapy plus placebo versus SRT plus enzalutamide with high-risk PSA-recurrent prostate cancer after radical prostatectomy (SALV-ENZA).
Autorzy:
Kapoor R; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Deek MP; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
McIntyre R; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Raman N; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Kummerlowe M; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Chen I; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Gaver M; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Wang H; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.
Denmeade S; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lotan T; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Paller C; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Markowski M; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.
Carducci M; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Eisenberger M; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Beer TM; OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Song DY; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
DeWeese TL; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA.; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Hearn JW; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Greco S; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
DeVille C; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA.
Desai NB; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Heath EI; Karmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
Liauw S; Department of Radiation Oncology and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Spratt DE; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Hung AY; Department of Radiation Medicine, OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Antonarakis ES; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA. .
Tran PT; Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD, 21231, USA. .; Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1650 Orleans Street, CRB1 Rm 1M45, Baltimore, MD, 21231, USA. .; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .
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Źródło:
BMC cancer [BMC Cancer] 2019 Jun 13; Vol. 19 (1), pp. 572. Date of Electronic Publication: 2019 Jun 13.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Adenocarcinoma*/mortality
Adenocarcinoma*/radiotherapy
Androgen Receptor Antagonists*/therapeutic use
Antineoplastic Agents*/therapeutic use
Phenylthiohydantoin*/analogs & derivatives
Phenylthiohydantoin*/therapeutic use
Prostatic Neoplasms, Castration-Resistant*/mortality
Prostatic Neoplasms, Castration-Resistant*/radiotherapy
Adult ; Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Young Adult ; Benzamides ; Double-Blind Method ; Neoplasm Metastasis ; Neoplasm Recurrence, Local ; Nitriles ; Placebos ; Prostatectomy ; Salvage Therapy ; Survival Analysis ; Treatment Outcome ; Multicenter Studies as Topic ; Randomized Controlled Trials as Topic ; Clinical Trials, Phase II as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A subset of calcium-binding S100 proteins show preferential heterodimerization.
Autorzy:
Spratt DE; Department of Biochemistry, The University of Western Ontario, London, Canada.
Barber KR; Department of Biochemistry, The University of Western Ontario, London, Canada.
Marlatt NM; Department of Biochemistry, The University of Western Ontario, London, Canada.
Ngo V; Department of Pathology and Laboratory Medicine, The University of Western Ontario, London, Canada.
Macklin JA; Department of Biochemistry, The University of Western Ontario, London, Canada.
Xiao Y; Department of Chemistry, The University of Western Ontario, London, Canada.
Konermann L; Department of Biochemistry, The University of Western Ontario, London, Canada.; Department of Chemistry, The University of Western Ontario, London, Canada.
Duennwald ML; Department of Pathology and Laboratory Medicine, The University of Western Ontario, London, Canada.
Shaw GS; Department of Biochemistry, The University of Western Ontario, London, Canada.
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Źródło:
The FEBS journal [FEBS J] 2019 May; Vol. 286 (10), pp. 1859-1876. Date of Electronic Publication: 2019 Feb 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
S100 Proteins/*chemistry
S100 Proteins/*metabolism
Green Fluorescent Proteins/chemistry ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HeLa Cells ; Humans ; Magnetic Resonance Spectroscopy ; Protein Multimerization ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; S100 Proteins/genetics ; Spectrometry, Mass, Electrospray Ionization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Adverse events in radiation oncology: A case series from wake up safe, the pediatric anesthesia quality improvement initiative.
Autorzy:
Christensen RE; Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
Nause-Osthoff RC; Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
Waldman JC; US Anesthesia Partners Colorado, Greenwood Village, Colorado.
Spratt DE; Radiation Oncology, University of Michigan, Ann Arbor, Michigan.
Hearn JWD; Radiation Oncology, University of Michigan, Ann Arbor, Michigan.
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Źródło:
Paediatric anaesthesia [Paediatr Anaesth] 2019 Mar; Vol. 29 (3), pp. 265-270. Date of Electronic Publication: 2019 Jan 29.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Anesthesia/*adverse effects
Radiotherapy/*adverse effects
Anesthesia Recovery Period ; Anesthesia, General ; Child ; Child, Preschool ; Humans ; Hypnotics and Sedatives ; Laryngeal Masks ; Propofol ; Quality Improvement/standards ; Radiation Oncology/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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