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Wyświetlanie 1-20 z 4442
Tytuł:
The feasibility of ultra-early and fast total‑body [  Ga]Ga-FAPI-04 PET/CT scan.
Autorzy:
Chen R; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Yang X; Central Research Institute, United Imaging Healthcare Group Co, Ltd, Shanghai, China.
Yu X; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Zhou X; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ng YL; Central Research Institute, United Imaging Healthcare Group Co, Ltd, Shanghai, China.
Chen Y; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Li L; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China.
Zhou Y; Central Research Institute, United Imaging Healthcare Group Co, Ltd, Shanghai, China.
Huang G; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China. .
Liu J; Department of Nuclear Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China. .
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Źródło:
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 Feb; Vol. 50 (3), pp. 661-666. Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:
Journal Article
MeSH Terms:
Positron Emission Tomography Computed Tomography*
Liver*
Humans ; Feasibility Studies ; Biological Transport ; Gallium Radioisotopes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tiffany Porta Siegel (Ed.): MALDI mass spectrometry imaging: from fundamentals to spatial omics.
Autorzy:
Strittmatter N; Fakultät für Chemie, Technische Universität München (TUM), Lichtenbergstraße 4, 85748, Garching, Germany. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2022 Jul; Vol. 414 (17), pp. 4791-4792. Date of Electronic Publication: 2022 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Liver*
Proteomics*/methods
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detection of salinomycin and lasalocid in chicken liver by icELISA based on functional bispecific single-chain antibody (scDb) and interpretation of molecular recognition mechanism.
Autorzy:
Chen Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, 100193, Beijing, People's Republic of China.
Zhao K; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, 100193, Beijing, People's Republic of China.
Huang J; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, 100193, Beijing, People's Republic of China.
Li M; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, 100193, Beijing, People's Republic of China.
Sun X; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, 100193, Beijing, People's Republic of China.
Li J; Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Beijing Laboratory of Food Quality and Safety, 100193, Beijing, People's Republic of China. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Nov; Vol. 413 (28), pp. 7031-7041. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Bispecific/*immunology
Enzyme-Linked Immunosorbent Assay/*methods
Lasalocid/*analysis
Liver/*chemistry
Pyrans/*analysis
Single-Chain Antibodies/*immunology
Animals ; Antibodies, Bispecific/chemistry ; Chickens ; Lasalocid/immunology ; Limit of Detection ; Pyrans/immunology ; Single-Chain Antibodies/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Quantitative mass spectrometry imaging of drugs and metabolites: a multiplatform comparison.
Autorzy:
Lamont L; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands.
Hadavi D; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands.
Viehmann B; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands.
Flinders B; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands.
Heeren RMA; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands.
Vreeken RJ; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands. .; Janssen Research & Development, 2340, Beerse, Belgium. .
Porta Siegel T; Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry, Maastricht University, 6229 ER, Maastricht, The Netherlands. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Apr; Vol. 413 (10), pp. 2779-2791. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Liver/*chemistry
Mass Spectrometry/*methods
Pharmaceutical Preparations/*analysis
Animals ; Dogs ; Limit of Detection ; Liver/metabolism ; Mass Spectrometry/instrumentation ; Pharmaceutical Preparations/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modification and validation of the Endopep-mass spectrometry method for botulinum neurotoxin detection in liver samples with application to samples collected during animal botulism outbreaks.
Autorzy:
Tevell Åberg A; Department of Chemistry, Environment, and Feed Hygiene, National Veterinary Institute (SVA), 751 89, Uppsala, Sweden.; Department of Medicinal Chemistry, Analytical Pharmaceutical Chemistry, Faculty of Pharmacy, Uppsala University, P.O. Box 574, 751 23, Uppsala, Sweden.
Karlsson I; Department of Chemistry, Environment, and Feed Hygiene, National Veterinary Institute (SVA), 751 89, Uppsala, Sweden.; Department of Medicinal Chemistry, Analytical Pharmaceutical Chemistry, Faculty of Pharmacy, Uppsala University, P.O. Box 574, 751 23, Uppsala, Sweden.
Hedeland M; Department of Chemistry, Environment, and Feed Hygiene, National Veterinary Institute (SVA), 751 89, Uppsala, Sweden. .; Department of Medicinal Chemistry, Analytical Pharmaceutical Chemistry, Faculty of Pharmacy, Uppsala University, P.O. Box 574, 751 23, Uppsala, Sweden. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Jan; Vol. 413 (2), pp. 345-354. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji:
Journal Article
MeSH Terms:
Botulinum Toxins/*analysis
Botulism/*diagnosis
Liver/*drug effects
Mass Spectrometry/*methods
Animals ; Biological Assay/methods ; Birds ; Botulism/veterinary ; Cattle ; Disease Outbreaks/veterinary ; Horses ; Limit of Detection ; Peptides/chemistry ; Protease Inhibitors/pharmacology ; Proteolysis ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Coadministration of metformin prevents olanzapine-induced metabolic dysfunction and regulates the gut-liver axis in rats.
Autorzy:
Luo C; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, People's Republic of China.; School of Life Sciences, Central South University, Changsha, 410078, Hunan, China.
Wang X; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, People's Republic of China.
Huang HX; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, People's Republic of China.
Mao XY; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, People's Republic of China.
Zhou HH; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, People's Republic of China.
Liu ZQ; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China. .; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, People's Republic of China. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2021 Jan; Vol. 238 (1), pp. 239-248. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji:
Journal Article
MeSH Terms:
Adjuvants, Pharmaceutic/*pharmacology
Gastrointestinal Microbiome/*drug effects
Liver/*drug effects
Metabolic Diseases/*prevention & control
Metformin/*pharmacology
Olanzapine/*adverse effects
Adjuvants, Pharmaceutic/administration & dosage ; Animals ; Bacteroides/isolation & purification ; Blood Glucose/metabolism ; Body Weight/drug effects ; Dose-Response Relationship, Drug ; Feces/microbiology ; Humans ; Lactobacillus gasseri/isolation & purification ; Liver/metabolism ; Male ; Metabolic Diseases/chemically induced ; Metformin/administration & dosage ; Olanzapine/administration & dosage ; RNA, Ribosomal, 16S/genetics ; Rats
SCR Organism:
Bacteroides acidifaciens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
One-pot fabrication of dual-emission and single-emission biomass carbon dots for Cu and tetracycline sensing and multicolor cellular imaging.
Autorzy:
Wu L; College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China.
Long R; College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China.
Li T; College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China.
Tang C; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China.; Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, Hunan, China.
Tong X; College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China.
Guo Y; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China. .; Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, Hunan, China. .
Shi S; College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China. .
Xiang H; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China. .
Tong C; College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, Hunan, China.
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 Nov; Vol. 412 (27), pp. 7481-7489. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji:
Journal Article
MeSH Terms:
Carbon/*chemistry
Copper/*analysis
Liver/*chemistry
Milk/*chemistry
Quantum Dots/*chemistry
Tetracyclines/*analysis
Animals ; Biomass ; Cations, Divalent/analysis ; Chive/chemistry ; Food Analysis/methods ; HeLa Cells ; Humans ; Limit of Detection ; Nanotechnology ; Spectrometry, Fluorescence/methods ; Swine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydrogen sulphide in liver glucose/lipid metabolism and non-alcoholic fatty liver disease.
Autorzy:
Mateus I; Institut Cochin, INSERM, CNRS, Université de Paris, Paris, France.
Prip-Buus C; Institut Cochin, INSERM, CNRS, Université de Paris, Paris, France.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2022 Mar; Vol. 52 (3), pp. e13680. Date of Electronic Publication: 2021 Oct 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lipid Metabolism*
Glucose/*metabolism
Hydrogen Sulfide/*metabolism
Liver/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Animals ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Total reflection X-ray fluorescence spectrometry for trace determination of iron and some additional elements in biological samples.
Autorzy:
Gruber A; Institute of Analytical and Bioanalytical Chemistry, Ulm University, 89081, Ulm, Germany.
Müller R; Institute of Analytical and Bioanalytical Chemistry, Ulm University, 89081, Ulm, Germany.
Wagner A; Institute of Comparative Molecular Endocrinology, Ulm University, 89081, Ulm, Germany.
Colucci S; Department of Pediatric Hematology, Oncology and Immunology, University of Heidelberg, 69120, Heidelberg, Germany.; Molecular Medicine Partnership Unit, 69120, Heidelberg, Germany.
Spasić MV; Institute of Comparative Molecular Endocrinology, Ulm University, 89081, Ulm, Germany.
Leopold K; Institute of Analytical and Bioanalytical Chemistry, Ulm University, 89081, Ulm, Germany. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 Sep; Vol. 412 (24), pp. 6419-6429. Date of Electronic Publication: 2020 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Iron/*analysis
Liver/*chemistry
Macrophages/*chemistry
Spectrometry, X-Ray Emission/*methods
Trace Elements/*analysis
Animals ; Cattle ; Cells, Cultured ; Limit of Detection ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment.
Autorzy:
Ren Y; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China.
Ding Y; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China.
Meng F; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China.
Jiang L; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China.
Li H; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China.
Huang J; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China.
Yu P; Xiangya School of Pharmaceutical Sciences, Central South University, No. 172, Tongzipo Road, Changsha, 410013, Hunan, China. CSU_.
Qiu Z; Hunan Key Laboratory for Bioanalysis of Complex Matrix Samples, C10 Building, Lugu S&T Park, No. 28, Lutian Road, Changsha, 410205, Hunan, China. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 Sep; Vol. 412 (22), pp. 5409-5418. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Chromatography, Liquid/*methods
Cytochrome P-450 CYP2E1/*metabolism
Liver/*enzymology
Tandem Mass Spectrometry/*methods
Amino Acid Sequence ; Animals ; Cytochrome P-450 CYP2E1/chemistry ; Limit of Detection ; Rats ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hepatic loss of CerS2 induces cell division defects via a mad2-mediated pathway.
Autorzy:
Cao M; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Zhang S; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Lam SM; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; Lipidall Technologies Company Limited, Changzhou, Jiangsu Province, China.
Shui G; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Jan; Vol. 12 (1), pp. e712.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Division/*genetics
Liver/*metabolism
Mad2 Proteins/*drug effects
Membrane Proteins/*antagonists & inhibitors
Sphingosine N-Acyltransferase/*antagonists & inhibitors
Tumor Suppressor Proteins/*antagonists & inhibitors
Animals ; Cell Division/drug effects ; Disease Models, Animal ; Mad2 Proteins/genetics ; Membrane Proteins/genetics ; Mice ; Sphingosine N-Acyltransferase/genetics ; Tumor Suppressor Proteins/genetics
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Discriminatory capacity of obesity indicators as predictors of high liver fat in US adolescents.
Autorzy:
Correa-Rodríguez M; Departament of Nursing, Health Sciences Faculty, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain.
Izquierdo M; Navarrabiomed, Complejo Hospitalario de Navarra (CHN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Spain.; CIBER of Frailty and Healthy Aging (CIBERFES), Institute of Health Carlos III, Madrid, Spain.
García-Hermoso A; Navarrabiomed, Complejo Hospitalario de Navarra (CHN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Spain.; Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, Universidad de Santiago de Chile (USACH), Santiago, Chile.
Ramírez-Vélez R; Navarrabiomed, Complejo Hospitalario de Navarra (CHN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Spain.; CIBER of Frailty and Healthy Aging (CIBERFES), Institute of Health Carlos III, Madrid, Spain.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2022 Jan; Vol. 52 (1), pp. e13654. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Adipose Tissue/*anatomy & histology
Liver/*anatomy & histology
Absorptiometry, Photon ; Adipose Tissue/diagnostic imaging ; Adolescent ; Body Composition ; Cross-Sectional Studies ; Female ; Humans ; Liver/diagnostic imaging ; Male ; Pediatric Obesity/diagnosis ; Predictive Value of Tests ; United States
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tissue pretreatment for LC-MS/MS analysis of PUFA and eicosanoid distribution in mouse brain and liver.
Autorzy:
Reinicke M; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Liebigstr. 27, 04103, Leipzig, Germany. .
Dorow J; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Liebigstr. 27, 04103, Leipzig, Germany.
Bischof K; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Liebigstr. 27, 04103, Leipzig, Germany.
Leyh J; Institute of Anatomy, Leipzig University, Liebigstr. 13, 04103, Leipzig, Germany.
Bechmann I; Institute of Anatomy, Leipzig University, Liebigstr. 13, 04103, Leipzig, Germany.
Ceglarek U; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Liebigstr. 27, 04103, Leipzig, Germany.; LIFE - Leipzig Research Center for Civilization Diseases, Leipzig University, Philipp-Rosenthal-Str. 27, 04103, Leipzig, Germany.
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 Apr; Vol. 412 (10), pp. 2211-2223. Date of Electronic Publication: 2019 Dec 21.
Typ publikacji:
Evaluation Study; Journal Article
MeSH Terms:
Chromatography, High Pressure Liquid/*methods
Eicosanoids/*chemistry
Fatty Acids, Unsaturated/*chemistry
Liver/*chemistry
Tandem Mass Spectrometry/*methods
Animals ; Brain/metabolism ; Brain Chemistry ; Eicosanoids/metabolism ; Fatty Acids, Unsaturated/metabolism ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hepatic gene expression variations in response to high-fat diet-induced impaired glucose tolerance using RNAseq analysis in collaborative cross mouse population.
Autorzy:
Abu-Toamih Atamni HJ; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, 69978, Tel Aviv, Israel.
Kontogianni G; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.
Binenbaum I; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.; Department of Biology, University of Patras, Patras, Greece.
Mott R; Department of Genetics, University College of London, London, UK.
Himmelbauer H; Centre for Genomic Regulation (CRG), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
Lehrach H; Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Chatziioannou A; Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, Greece.; e-NIOS Applications PC, 17671, Kallithea, Greece.
Iraqi FA; Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, 69978, Tel Aviv, Israel. .
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2019 Oct; Vol. 30 (9-10), pp. 260-275. Date of Electronic Publication: 2019 Oct 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diet, High-Fat/*adverse effects
Glucose Intolerance/*genetics
Liver/*metabolism
Animals ; Collaborative Cross Mice/genetics ; Collaborative Cross Mice/metabolism ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Female ; Gene Expression ; Glucose Intolerance/metabolism ; Male ; Mice ; Mice, Inbred Strains ; Sequence Analysis, RNA ; Sex Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Liver size and lipid content differences between BALB/c and BALB/cJ mice on a high-fat diet are due, in part, to Zhx2.
Autorzy:
Clinkenbeard EL; Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Turpin C; Department of Pharmacology & Nutritional Sciences, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.
Jiang J; Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.
Peterson ML; Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.
Spear BT; Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY, 40536, USA. .; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40536, USA. .
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2019 Aug; Vol. 30 (7-8), pp. 226-236. Date of Electronic Publication: 2019 Jul 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Diet, High-Fat/*adverse effects
Homeodomain Proteins/*genetics
Lipid Metabolism/*genetics
Liver/*pathology
Alanine Transaminase/blood ; Animals ; Female ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Lipids/blood ; Liver/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Transgenic ; Mutation ; Weight Gain/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preliminary results of the Phase 1 Lip-Re I clinical trial: biodistribution and dosimetry assessments in hepatocellular carcinoma patients treated with Re-SSS Lipiodol radioembolization.
Autorzy:
Delaunay K; Department of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes, cedex, France.; University of Rennes 1, Rennes, France.
Edeline J; University of Rennes 1, Rennes, France.; Department of Medical Oncology, Cancer Institute Eugène Marquis, Rennes, France.; INSERM INRA UMR 1241 NuMeCan, University of Rennes 1, Rennes, France.
Rolland Y; Department of Medical Imaging, Cancer Institute Eugène Marquis, Rennes, France.; INSERM UMR 1099 LTSI, University of Rennes 1, Rennes, France.
Lepareur N; INSERM INRA UMR 1241 NuMeCan, University of Rennes 1, Rennes, France.; Radiopharmacy, Cancer Institute Eugène Marquis, Rennes, France.
Laffont S; Department of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes, cedex, France.
Palard X; Department of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes, cedex, France.; University of Rennes 1, Rennes, France.
Bouvry C; Radiopharmacy, Cancer Institute Eugène Marquis, Rennes, France.
Le Sourd S; Department of Medical Oncology, Cancer Institute Eugène Marquis, Rennes, France.
Pracht M; Department of Medical Oncology, Cancer Institute Eugène Marquis, Rennes, France.
Ardisson V; Radiopharmacy, Cancer Institute Eugène Marquis, Rennes, France.
Noiret N; ENSCR, CNRS, ISCR [(Institut des Sciences Chimiques de Rennes)] - UMR 6226, University of Rennes, F-35000, Rennes, France.
Bellissant É; University of Rennes 1, Rennes, France.; INSERM CIC 1414 Clinical Investigation Center, Rennes, France.; Department of Clinical and Biological Pharmacology and Pharmacovigilance, Pharmaco-epidemiology and Drug Information Center, Rennes University Hospital, Rennes, France.
Garin E; Department of Nuclear Medicine, Cancer Institute Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, CS 44229, 35042, Rennes, cedex, France. .; University of Rennes 1, Rennes, France. .; INSERM INRA UMR 1241 NuMeCan, University of Rennes 1, Rennes, France. .
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Źródło:
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2019 Jul; Vol. 46 (7), pp. 1506-1517. Date of Electronic Publication: 2019 Feb 04.
Typ publikacji:
Clinical Trial, Phase I; Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*diagnostic imaging
Carcinoma, Hepatocellular/*therapy
Embolization, Therapeutic/*methods
Liver/*diagnostic imaging
Liver Neoplasms/*diagnostic imaging
Liver Neoplasms/*therapy
Aged ; Disease Progression ; Drug Combinations ; Female ; Humans ; Injections, Intra-Arterial ; Iodized Oil ; Lung/diagnostic imaging ; Male ; Middle Aged ; Organometallic Compounds ; Prospective Studies ; Radiometry ; Radiopharmaceuticals/therapeutic use ; Tissue Distribution ; Tomography, Emission-Computed, Single-Photon ; Tomography, X-Ray Computed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Matrix-assisted laser desorption ionization - mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non-small-cell lung cancer mouse xenograft model.
Autorzy:
Kim TY; Chemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
Lee B; Division of Clinical Protein Science and Imaging, Department of Clinical Sciences (Lund) and Department of Biomedical Engineering, Lund University, Lund, Sweden.
Kim Y; Division of Clinical Protein Science and Imaging, Department of Clinical Sciences (Lund) and Department of Biomedical Engineering, Lund University, Lund, Sweden.
Sugihara Y; Division of Clinical Protein Science and Imaging, Department of Clinical Sciences (Lund) and Department of Biomedical Engineering, Lund University, Lund, Sweden.
Rezeli M; Division of Clinical Protein Science and Imaging, Department of Clinical Sciences (Lund) and Department of Biomedical Engineering, Lund University, Lund, Sweden.
Szasz AM; Division of Clinical Protein Science and Imaging, Department of Clinical Sciences (Lund) and Department of Biomedical Engineering, Lund University, Lund, Sweden.; Department of Tumor Biology, National Korányi Institute of Pulmonology, Budapest, Hungary.
Dome B; Department of Tumor Biology, National Korányi Institute of Pulmonology, Budapest, Hungary.; Division of Thoracic Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.
Marko-Varga G; Division of Clinical Protein Science and Imaging, Department of Clinical Sciences (Lund) and Department of Biomedical Engineering, Lund University, Lund, Sweden.
Kwon HJ; Chemical Genomics Global Research Lab, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Jul; Vol. 11 (7), pp. e481.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization*/methods
Erlotinib Hydrochloride/*metabolism
Kidney/*metabolism
Liver/*metabolism
Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Erlotinib Hydrochloride/therapeutic use ; Humans ; Kidney/chemistry ; Kidney/diagnostic imaging ; Liver/chemistry ; Liver/diagnostic imaging ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Tissue Distribution ; Transplantation, Heterologous
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis.
Autorzy:
Junge N; Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany. .
Tiedau M; Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Verboom M; Institute for Transfusion Medicine, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Hallensleben M; Institute for Transfusion Medicine, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Blasczyk R; Institute for Transfusion Medicine, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Schlue J; Institute for Pathology, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Goldschmidt I; Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Pfister ED; Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
Baumann U; Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.
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Źródło:
European journal of pediatrics [Eur J Pediatr] 2016 Apr; Vol. 175 (4), pp. 527-37. Date of Electronic Publication: 2015 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cholangitis, Sclerosing/*diagnosis
HLA-DRB1 Chains/*immunology
Hepatitis, Autoimmune/*diagnosis
Liver/*pathology
Adolescent ; Adult ; Aged ; Alleles ; Biomarkers ; Child ; Child, Preschool ; Cholangitis, Sclerosing/immunology ; Female ; HLA-DRB1 Chains/genetics ; Hepatitis, Autoimmune/immunology ; Humans ; Infant ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Sensitivity and Specificity ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Changes in whole-body fat distribution, intrahepatic lipids, and insulin resistance of obese adolescents during a low-level lifestyle intervention.
Autorzy:
Springer F; Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Hoppe-Seyler-Str.3, 72076, Tübingen, Germany. fabian-springer@gmx.de.
Ballweg V; Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Hoppe-Seyler-Str.3, 72076, Tübingen, Germany. .
Schweizer R; Paediatric Endocrinology and Diabetes, University Children's Hospital Tübingen, Hoppe-Seyler-Str.1, 72076, Tübingen, Germany. .
Schick F; Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Hoppe-Seyler-Str.3, 72076, Tübingen, Germany. .
Ranke MB; Paediatric Endocrinology and Diabetes, University Children's Hospital Tübingen, Hoppe-Seyler-Str.1, 72076, Tübingen, Germany. .
Binder G; Paediatric Endocrinology and Diabetes, University Children's Hospital Tübingen, Hoppe-Seyler-Str.1, 72076, Tübingen, Germany. .
Ehehalt S; Paediatric Endocrinology and Diabetes, University Children's Hospital Tübingen, Hoppe-Seyler-Str.1, 72076, Tübingen, Germany. .; Public Health Department of Stuttgart, Department of Pediatrics, Dental Health Care, Health Promotion, and Social Services, Schloßstr.91, 70176, Stuttgart, Germany. .
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Corporate Authors:
DISKUS Study Group
Źródło:
European journal of pediatrics [Eur J Pediatr] 2015 Dec; Vol. 174 (12), pp. 1603-12. Date of Electronic Publication: 2015 Jun 16.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Body Fat Distribution*
Insulin Resistance*
Lipid Metabolism*
Liver/*metabolism
Obesity/*metabolism
Adipose Tissue/metabolism ; Adolescent ; Body Mass Index ; Child ; Female ; Humans ; Life Style ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Male ; Obesity/physiopathology ; Obesity/therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity.
Autorzy:
Serafim TL; CNC-Center for Neuroscience and Cell Biology, UC-Biotech, University of Coimbra, Cantanhede, Portugal.
Cunha-Oliveira T; CNC-Center for Neuroscience and Cell Biology, UC-Biotech, University of Coimbra, Cantanhede, Portugal.
Deus CM; CNC-Center for Neuroscience and Cell Biology, UC-Biotech, University of Coimbra, Cantanhede, Portugal.
Sardão VA; CNC-Center for Neuroscience and Cell Biology, UC-Biotech, University of Coimbra, Cantanhede, Portugal.
Cardoso IM; CNC-Center for Neuroscience and Cell Biology, UC-Biotech, University of Coimbra, Cantanhede, Portugal.
Yang S; Department of Animal Science, University of Wyoming, Laramie, WY, USA.
Odhiambo JF; Department of Animal Science, University of Wyoming, Laramie, WY, USA.
Ghnenis AB; Department of Animal Science, University of Wyoming, Laramie, WY, USA.
Smith AM; Department of Animal Science, University of Wyoming, Laramie, WY, USA.
Li J; Department of Radiology, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Nathanielsz PW; Department of Animal Science, University of Wyoming, Laramie, WY, USA.
Ford SP; Department of Animal Science, University of Wyoming, Laramie, WY, USA.
Oliveira PJ; CNC-Center for Neuroscience and Cell Biology, UC-Biotech, University of Coimbra, Cantanhede, Portugal.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2021 Feb; Vol. 51 (2), pp. e13375. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*physiology
Electron Transport/*physiology
Fetus/*metabolism
Liver/*metabolism
Mitochondria, Liver/*metabolism
Obesity, Maternal/*metabolism
Animals ; Beclin-1/metabolism ; Cardiolipins/metabolism ; Cathepsin B/metabolism ; Cathepsin D/metabolism ; Female ; Microtubule-Associated Proteins/metabolism ; Phospholipids/metabolism ; Pregnancy ; Sheep ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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