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Tytuł :
R-Spondins 2 and 3 Are Overexpressed in a Subset of Human Colon and Breast Cancers.
Autorzy :
Conboy CB; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
Vélez-Reyes GL; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
Rathe SK; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
Abrahante JE; University of Minnesota Informatics Institute, Minneapolis, Minnesota, USA.
Temiz NA; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
Burns MB; Biochemistry, Molecular Biology and Biophysics Department, University of Minnesota, Minneapolis, Minnesota, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, USA.
Harris RS; Biochemistry, Molecular Biology and Biophysics Department, University of Minnesota, Minneapolis, Minnesota, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, USA.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, Minnesota, USA.
Starr TK; Department of Obstetrics, Gynecology and Women's Health and University of Minnesota, Minneapolis, Minnesota, USA.
Largaespada DA; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Jan; Vol. 40 (1), pp. 70-79. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*genetics
Breast Neoplasms/*genetics
Colonic Neoplasms/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
Thrombospondins/*genetics
Adenocarcinoma/metabolism ; Breast Neoplasms/metabolism ; Cell Line ; Colonic Neoplasms/metabolism ; Female ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; MCF-7 Cells ; Male ; Receptors, G-Protein-Coupled/metabolism ; Thrombospondins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Up-Regulation ; Wnt Signaling Pathway
Czasopismo naukowe
Tytuł :
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
Autorzy :
Law EK; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
Levin-Klein R; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
Jarvis MC; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
Kim H; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Argyris PP; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.; Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN.
Carpenter MA; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
Starrett GJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.; Laboratory of Cellular Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Temiz NA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Health Informatics, University of Minnesota, Minneapolis, MN.
Larson LK; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
Durfee C; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
Burns MB; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.; Department of Biology, Loyola University, Chicago, IL.
Vogel RI; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, MN.
Stavrou S; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL.
Aguilera AN; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL.
Wagner S; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Department of Pediatrics, University of Minnesota, Minneapolis, MN.
Largaespada DA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Department of Pediatrics, University of Minnesota, Minneapolis, MN.
Starr TK; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, MN.
Ross SR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL.
Harris RS; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2020 Dec 07; Vol. 217 (12).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis.
Autorzy :
Tiwari A; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California. Electronic address: .
Tashiro K; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Dixit A; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota.
Soni A; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Vogel K; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Hall B; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Shafqat I; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Slaughter J; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Param N; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Le A; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Saunders E; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Paithane U; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Garcia G; Histology Core, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Campos AR; Proteomics Core, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Zettervall J; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota.
Carlson M; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota.
Starr TK; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Marahrens Y; Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota.
Deshpande AJ; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Commisso C; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Provenzano PP; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota.
Bagchi A; Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California. Electronic address: .
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Źródło :
Gastroenterology [Gastroenterology] 2020 Nov; Vol. 159 (5), pp. 1882-1897.e5. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma.
Autorzy :
Geistlinger L; Graduate School of Public Health and Health Policy, City University of New York, New York, New York.; Institute for Implementation Science and Population Health, City University of New York, New York, New York.
Oh S; Graduate School of Public Health and Health Policy, City University of New York, New York, New York.; Institute for Implementation Science and Population Health, City University of New York, New York, New York.
Ramos M; Graduate School of Public Health and Health Policy, City University of New York, New York, New York.; Institute for Implementation Science and Population Health, City University of New York, New York, New York.; Roswell Park Comprehensive Cancer Institute, Buffalo, New York.
Schiffer L; Graduate School of Public Health and Health Policy, City University of New York, New York, New York.; Institute for Implementation Science and Population Health, City University of New York, New York, New York.
LaRue RS; Minnesota Supercomputing Institute, Minneapolis, Minnesota.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Henzler CM; Minnesota Supercomputing Institute, Minneapolis, Minnesota.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Munro SA; Minnesota Supercomputing Institute, Minneapolis, Minnesota.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Daughters C; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Nelson AC; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.; University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota.
Winterhoff BJ; University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota.; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Chang Z; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Talukdar S; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Shetty M; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Mullany SA; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Morgan M; Roswell Park Comprehensive Cancer Institute, Buffalo, New York.
Parmigiani G; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Birrer MJ; The Winthrop P Rockefeller Cancer Institute, University of Arkansas Medical Sciences, Little Rock, Arkansas.
Qin LX; Memorial Sloan Kettering Cancer Center, New York, New York.
Riester M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
Starr TK; University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota.; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Waldron L; Graduate School of Public Health and Health Policy, City University of New York, New York, New York. .; Institute for Implementation Science and Population Health, City University of New York, New York, New York.
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Źródło :
Cancer research [Cancer Res] 2020 Oct 15; Vol. 80 (20), pp. 4335-4345. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cystadenocarcinoma, Serous/*genetics
Cystadenocarcinoma, Serous/*pathology
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*pathology
Female ; Gene Expression Profiling ; Genomic Instability ; Humans ; Ploidies ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Mesenchymal Stem Cells As Guideposts for Nanoparticle-Mediated Targeted Drug Delivery in Ovarian Cancer.
Autorzy :
Layek B; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Shetty M; Department of Obstetrics, Gynecology and Women's Health (OBGYN), University of Minnesota, Minneapolis, MN 55455, USA.
Nethi SK; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.; Fels Institute for Cancer Research & Molecular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Sehgal D; School of Pharmacy, Temple University, Philadelphia, PA 19140, USA.
Starr TK; Department of Obstetrics, Gynecology and Women's Health (OBGYN), University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Prabha S; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.; Fels Institute for Cancer Research & Molecular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
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Źródło :
Cancers [Cancers (Basel)] 2020 Apr 14; Vol. 12 (4). Date of Electronic Publication: 2020 Apr 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.
Autorzy :
Pomeroy EJ; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Hunzeker JT; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Kluesner MG; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Lahr WS; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Smeester BA; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Crosby MR; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Lonetree CL; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Yamamoto K; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Bendzick L; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, MN 55455, USA.
Miller JS; Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.
Geller MA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, MN 55455, USA.
Walcheck B; Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, MN 55455, USA.
Felices M; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.
Webber BR; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.
Starr TK; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, MN 55455, USA.
Moriarity BS; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: .
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 Jan 08; Vol. 28 (1), pp. 52-63. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adoptive Transfer/*methods
Cell Engineering/*methods
Genetic Engineering/*methods
Killer Cells, Natural/*immunology
Ovarian Neoplasms/*therapy
ADAM17 Protein/genetics ; Animals ; CRISPR-Cas Systems ; Cytotoxicity, Immunologic/genetics ; Female ; Gene Knockout Techniques ; Healthy Volunteers ; Humans ; K562 Cells ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Ovarian Neoplasms/pathology ; Parvovirinae/genetics ; Programmed Cell Death 1 Receptor/genetics ; Treatment Outcome ; Xenograft Model Antitumor Assays
SCR Organism :
Adeno-associated virus-1
Czasopismo naukowe
Tytuł :
R-spondin 2 Drives Liver Tumor Development in a Yes-Associated Protein-Dependent Manner.
Autorzy :
Conboy CB; Masonic Cancer Center University of Minnesota Minneapolis MN.
Vélez-Reyes GL; Masonic Cancer Center University of Minnesota Minneapolis MN.
Tschida BR; Masonic Cancer Center University of Minnesota Minneapolis MN.
Hu H; Masonic Cancer Center University of Minnesota Minneapolis MN.
Kaufmann G; Masonic Cancer Center University of Minnesota Minneapolis MN.
Koes N; Masonic Cancer Center University of Minnesota Minneapolis MN.
Keller B; Masonic Cancer Center University of Minnesota Minneapolis MN.
Alsinet C; Liver Cancer Translational Research Laboratory Liver Unit, L'Institut d'Investigacions Biomèdiques August Pi i Sunyer-Hospital Clinic of Barcelona University of Barcelona Barcelona Spain.
Cornellà H; Liver Cancer Translational Research Laboratory Liver Unit, L'Institut d'Investigacions Biomèdiques August Pi i Sunyer-Hospital Clinic of Barcelona University of Barcelona Barcelona Spain.
Pinyol R; Liver Cancer Translational Research Laboratory Liver Unit, L'Institut d'Investigacions Biomèdiques August Pi i Sunyer-Hospital Clinic of Barcelona University of Barcelona Barcelona Spain.
Abrahante JE; University of Minnesota Informatics Institute Minneapolis MN.
Temiz NA; Masonic Cancer Center University of Minnesota Minneapolis MN.
Linden MA; Comparative Pathology Shared Resource University of Minnesota St. Paul MN.; Department of Medicine Division of Hematology, Oncology, and Transplantation University of Minnesota Minneapolis MN.
Amin K; Comparative Pathology Shared Resource University of Minnesota St. Paul MN.; Department of Medicine Division of Hematology, Oncology, and Transplantation University of Minnesota Minneapolis MN.
Kuka TP; Masonic Cancer Center University of Minnesota Minneapolis MN.
Keng VW; Masonic Cancer Center University of Minnesota Minneapolis MN.; Department of Applied Biology and Chemical Technology Hong Kong Polytechnic University Kowloon Hong Kong.
Llovet JM; Liver Cancer Translational Research Laboratory Liver Unit, L'Institut d'Investigacions Biomèdiques August Pi i Sunyer-Hospital Clinic of Barcelona University of Barcelona Barcelona Spain.; Mount Sinai Liver Cancer Program Division of Liver Diseases Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai New York NY.; Catalan Institution for Research and Advanced Studies Barcelona Spain.
Starr TK; Department of Obstetrics, Gynecology, and Women's Health University of Minnesota Minneapolis MN.
Largaespada DA; Masonic Cancer Center University of Minnesota Minneapolis MN.; Department of Pediatrics University of Minnesota Minneapolis MN.
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Źródło :
Hepatology communications [Hepatol Commun] 2019 Sep 03; Vol. 3 (11), pp. 1496-1509. Date of Electronic Publication: 2019 Sep 03 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
De novo prediction of cell-type complexity in single-cell RNA-seq and tumor microenvironments.
Autorzy :
Woo J; Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
Winterhoff BJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, USA.
Starr TK; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, USA.
Aliferis C; Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
Wang J; Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA .; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
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Źródło :
Life science alliance [Life Sci Alliance] 2019 Jul 02; Vol. 2 (4). Date of Electronic Publication: 2019 Jul 02 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
RNA-Seq*
Single-Cell Analysis/*methods
Tumor Microenvironment/*genetics
Algorithms ; Bayes Theorem ; Blood Cells/metabolism ; Cell Line, Tumor ; Computational Biology/methods ; Glucagon-Secreting Cells/metabolism ; Humans ; Melanoma/genetics ; Melanoma/metabolism ; Software ; Transcriptome/genetics ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Intercellular Transfer of Oncogenic KRAS via Tunneling Nanotubes Introduces Intracellular Mutational Heterogeneity in Colon Cancer Cells.
Autorzy :
Desir S; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA. .; Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, 55455 MN, USA. .
Wong P; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA. .; Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN 55455, USA. .
Turbyville T; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA. .
Chen; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA. .
Shetty M; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN 55455, USA. .
Clark C; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN 55455, USA. .
Zhai E; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA. .
Romin Y; Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. .
Manova-Todorova K; Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. .
Starr TK; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, MN 55455, USA. .
Nissley DV; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA. .
Steer CJ; Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN 55455, USA. .
Subramanian S; Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA. .
Lou E; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA. .
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Źródło :
Cancers [Cancers (Basel)] 2019 Jun 26; Vol. 11 (7). Date of Electronic Publication: 2019 Jun 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Biological Insights into Chemotherapy Resistance in Ovarian Cancer.
Autorzy :
Glasgow MA; Department of Obstetrics, Gynecology & Women's Health, University of Minnesota, Minneapolis, MN 55455, USA. .
Argenta P; Department of Obstetrics, Gynecology & Women's Health, University of Minnesota, Minneapolis, MN 55455, USA. .
Abrahante JE; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA. .
Shetty M; Department of Obstetrics, Gynecology & Women's Health, University of Minnesota, Minneapolis, MN 55455, USA. .
Talukdar S; Department of Obstetrics, Gynecology & Women's Health, University of Minnesota, Minneapolis, MN 55455, USA. .
Croonquist PA; Department of Biology, Anoka Ramsey Community College, Coon Rapids, MN 55455, USA. .
Khalifa MA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA. .
Starr TK; Department of Obstetrics, Gynecology & Women's Health, University of Minnesota, Minneapolis, MN 55455, USA. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Apr 30; Vol. 20 (9). Date of Electronic Publication: 2019 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
Transcriptome*
Drug Resistance, Neoplasm/*genetics
Ovarian Neoplasms/*drug therapy
Aged ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Middle Aged ; Neoadjuvant Therapy ; Ovarian Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Simultaneous Measurement of 92 Serum Protein Biomarkers for the Development of a Multiprotein Classifier for Ovarian Cancer Detection.
Autorzy :
Skubitz APN; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota. .; Ovarian Cancer Early Detection Program, University of Minnesota, Minneapolis, Minnesota.; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Boylan KLM; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.; Ovarian Cancer Early Detection Program, University of Minnesota, Minneapolis, Minnesota.
Geschwind K; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.; Ovarian Cancer Early Detection Program, University of Minnesota, Minneapolis, Minnesota.
Cao Q; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Starr TK; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota.
Geller MA; Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Celestino J; University of Texas, MD Anderson Cancer Center, Houston, Texas.
Bast RC Jr; University of Texas, MD Anderson Cancer Center, Houston, Texas.
Lu KH; University of Texas, MD Anderson Cancer Center, Houston, Texas.
Koopmeiners JS; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.
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Źródło :
Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2019 Mar; Vol. 12 (3), pp. 171-184. Date of Electronic Publication: 2019 Feb 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biomarkers, Tumor/*analysis
Blood Proteins/*metabolism
Cystadenocarcinoma, Serous/*blood
Cystadenocarcinoma, Serous/*pathology
Ovarian Neoplasms/*blood
Ovarian Neoplasms/*classification
Blood Proteins/analysis ; Case-Control Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Ovarian Neoplasms/pathology ; Protein Array Analysis ; ROC Curve
Czasopismo naukowe
Tytuł :
Meta-analytic framework for modeling genetic coexpression dynamics.
Autorzy :
Kinzy TG; Case Western Reserve University, Cleveland, USA.
Starr TK; University of Minnesota, Minneapolis, USA.
Tseng GC; University of Pittsburgh, Pittsburgh, USA.
Ho YY; Department of Statistics, University of South Carolina, Columbia, SC29209,USA.
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Źródło :
Statistical applications in genetics and molecular biology [Stat Appl Genet Mol Biol] 2019 Feb 09; Vol. 18 (1). Date of Electronic Publication: 2019 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Network Meta-Analysis*
Gene Expression Profiling/*statistics & numerical data
Oligonucleotide Array Sequence Analysis/*statistics & numerical data
Algorithms ; Bayes Theorem ; Epistasis, Genetic/genetics ; Gene Regulatory Networks/genetics
Czasopismo naukowe
Tytuł :
Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma.
Autorzy :
Rahrmann EP; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota. .; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Wolf NK; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota.
Otto GM; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Heltemes-Harris L; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Lab Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.; Department of Laboratory Medicine and Pathology, Division of Hematopathology, University of Minnesota, Minneapolis, Minnesota.
Ramsey LB; Department of Laboratory Medicine and Pathology, Division of Hematopathology, University of Minnesota, Minneapolis, Minnesota.
Shu J; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
LaRue RS; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Linden MA; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Center for Immunology, University of Minnesota, Minneapolis, Minnesota.
Rathe SK; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Starr TK; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Ob-Gyn and Women's Health, University of Minnesota, Minneapolis, Minnesota.
Farrar MA; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Lab Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.; Department of Laboratory Medicine and Pathology, Division of Hematopathology, University of Minnesota, Minneapolis, Minnesota.
Moriarity BS; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Largaespada DA; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
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Źródło :
Molecular cancer research : MCR [Mol Cancer Res] 2019 Feb; Vol. 17 (2), pp. 567-582. Date of Electronic Publication: 2018 Oct 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*genetics
Lymphoma, Large B-Cell, Diffuse/*genetics
Transcription Factors/*genetics
Animals ; Cell Line, Tumor ; Humans ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Lymphoma, Large B-Cell, Diffuse/pathology ; MAP Kinase Signaling System ; Mice ; Mice, Transgenic ; Mutagenesis, Insertional ; Mutation
Czasopismo naukowe
Tytuł :
Single-cell sequencing in ovarian cancer: a new frontier in precision medicine.
Autorzy :
Winterhoff B; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health.; Masonic Cancer Center.
Talukdar S; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health.
Chang Z; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health.
Wang J; Institute of Health Informatics, University of Minnesota, Minneapolis, Minnesota, USA.
Starr TK; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health.; Masonic Cancer Center.
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Źródło :
Current opinion in obstetrics & gynecology [Curr Opin Obstet Gynecol] 2019 Feb; Vol. 31 (1), pp. 49-55.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
High-Throughput Nucleotide Sequencing*
Precision Medicine*/trends
Single-Cell Analysis*/trends
Carcinoma, Ovarian Epithelial/*pathology
Neoplastic Cells, Circulating/*drug effects
Biomarkers, Tumor ; Carcinoma, Ovarian Epithelial/immunology ; Carcinoma, Ovarian Epithelial/therapy ; Cell Separation ; Female ; Gene Expression Profiling ; Humans ; Neoplastic Cells, Circulating/immunology ; Sequence Analysis, DNA
Czasopismo naukowe

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