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Tytuł :
Fast diagnostic test for familial Mediterranean fever based on a kinase inhibitor.
Autorzy :
Magnotti F; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, Lyon, France.
Malsot T; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, Lyon, France.
Georgin-Lavialle S; Internal Medicine, Tenon Hospital, AP-HP, Paris, France.; CEREMAIA (Centre de Référence des Maladies Autoinflammatoires et des Amyloses), Paris, France.
Abbas F; Biostatistics, Pôle de Santé Publique,CNRS UMR5308, Hospices Civils de Lyon, Lyon, France.
Martin A; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, Lyon, France.
Belot A; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, Lyon, France.; CEREMAIA (Centre de Référence des Maladies Autoinflammatoires et des Amyloses), Paris, France.; Department of Paediatric Nephrology, Rheumatology, Dermatology, Hôpital Femme-Mère Enfant, Université Claude Bernard-Lyon 1, Hospices Civils de Lyon, Bron, France.
Fauter M; Internal Medicine, University Hospital Croix-Rousse, Hospices Civils de Lyon, Lyon, France.; Internal Medicine, Hospices Civils de Lyon, Lyon, France.
Rabilloud M; Biostatistics, Pôle de Santé Publique,CNRS UMR5308, Hospices Civils de Lyon, Lyon, France.
Gerfaud-Valentin M; Internal Medicine, University Hospital Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Sève P; Internal Medicine, University Hospital Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Duquesne A; Department of Paediatric Nephrology, Rheumatology, Dermatology, Hôpital Femme-Mère Enfant, Université Claude Bernard-Lyon 1, Hospices Civils de Lyon, Bron, France.
Hot A; Internal Medicine, University Hospital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Durupt S; Internal Medicine, University Hospital Lyon Sud, Hospices Civils de Lyon, Lyon, France.
Savey L; Internal Medicine, Tenon Hospital, AP-HP, Paris, France.
Giurgea I; Genetics, Armand-Trousseau Hospital, APHP, Sorbonne University, Paris, Île-de-France, France.
Grateau G; Internal Medicine, Tenon Hospital, AP-HP, Paris, France.; CEREMAIA (Centre de Référence des Maladies Autoinflammatoires et des Amyloses), Paris, France.
Henry T; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, Lyon, France.
Jamilloux Y; Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard-Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, Lyon, France .; Internal Medicine, University Hospital Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Jan; Vol. 80 (1), pp. 128-132. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Familial Mediterranean Fever/*diagnosis
Inflammasomes/*drug effects
Interleukin-1beta/*drug effects
Monocytes/*drug effects
Protein Kinase Inhibitors/*pharmacology
Pyrin/*drug effects
Pyroptosis/*drug effects
Staurosporine/*analogs & derivatives
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arthritis, Juvenile/diagnosis ; Behcet Syndrome/diagnosis ; Case-Control Studies ; Child ; Child, Preschool ; Cryopyrin-Associated Periodic Syndromes/diagnosis ; Familial Mediterranean Fever/genetics ; Familial Mediterranean Fever/immunology ; Female ; Fever/diagnosis ; Fever of Unknown Origin/diagnosis ; Hereditary Autoinflammatory Diseases/diagnosis ; Humans ; Immunologic Tests/methods ; Inflammasomes/immunology ; Inflammasomes/metabolism ; Interleukin-1beta/immunology ; Interleukin-1beta/metabolism ; Lupus Erythematosus, Systemic/diagnosis ; Male ; Mevalonate Kinase Deficiency/diagnosis ; Middle Aged ; Monocytes/immunology ; Monocytes/metabolism ; Pyrin/genetics ; Pyrin/immunology ; Pyrin/metabolism ; Sensitivity and Specificity ; Sepsis/diagnosis ; Staurosporine/pharmacology ; Still's Disease, Adult-Onset/diagnosis ; Young Adult
SCR Disease Name :
Periodic fever, familial, autosomal dominant
Czasopismo naukowe
Tytuł :
Midostaurin in acute myeloid leukemia: current evidence and practical considerations in routine clinical use.
Autorzy :
Abdul-Hamil NA; Department of Hematology, Singapore General Hospital, Singapore, Singapore - .
Wong GC; Department of Hematology, Singapore General Hospital, Singapore, Singapore.; SingHealth Duke-NUS Blood Cancer Center, Singapore, Singapore.
Nagarajan C; Department of Hematology, Singapore General Hospital, Singapore, Singapore.; SingHealth Duke-NUS Blood Cancer Center, Singapore, Singapore.
Martinelli G; Unit of Hematology, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Forlì-Cesena, Italy.
Cherchione C; Unit of Hematology, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Forlì-Cesena, Italy.
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Źródło :
Minerva medica [Minerva Med] 2020 Oct; Vol. 111 (5), pp. 443-454. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Staurosporine/*analogs & derivatives
fms-Like Tyrosine Kinase 3/*genetics
Aniline Compounds/therapeutic use ; Anthracyclines/therapeutic use ; Antifungal Agents/therapeutic use ; Antineoplastic Agents/metabolism ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Clinical Trials as Topic ; Cytarabine/therapeutic use ; Cytochrome P-450 CYP3A Inhibitors/pharmacology ; Drug Interactions ; Echinocandins/therapeutic use ; Forecasting ; Hematopoietic Stem Cell Transplantation ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/therapy ; Maintenance Chemotherapy ; Mutation ; Mycoses/prevention & control ; Protein Kinase Inhibitors/metabolism ; Pyrazines/therapeutic use ; Randomized Controlled Trials as Topic ; Recurrence ; Staurosporine/metabolism ; Staurosporine/therapeutic use ; Triazoles/therapeutic use ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Monocytic Maturation Induced by FLT3 Inhibitor Therapy of Acute Myeloid Leukemia: Morphologic and Immunophenotypic Characteristics.
Autorzy :
Arries CD; University of Minnesota, Minneapolis, MN.
Yohe SL; University of Minnesota, Minneapolis, MN.
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Źródło :
Laboratory medicine [Lab Med] 2020 Sep 01; Vol. 51 (5), pp. 478-483.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Antineoplastic Agents/*adverse effects
Bone Marrow Cells/*drug effects
Leukemia, Myeloid, Acute/*drug therapy
Staurosporine/*analogs & derivatives
fms-Like Tyrosine Kinase 3/*antagonists & inhibitors
Bone Marrow Cells/pathology ; Cell Differentiation/drug effects ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Male ; Middle Aged ; Monocytes/cytology ; Staurosporine/adverse effects ; Young Adult ; fms-Like Tyrosine Kinase 3/genetics
Czasopismo naukowe
Tytuł :
Midostaurin improves quality of life and mediator-related symptoms in advanced systemic mastocytosis.
Autorzy :
Hartmann K; Division of Allergy, Department of Dermatology, University of Basel, Basel, Switzerland; Department of Biomedicine, University of Basel, Basel, Switzerland. Electronic address: .
Gotlib J; Stanford University School of Medicine, Stanford, Calif.
Akin C; Brigham and Women's Hospital, Boston, Mass.
Hermine O; University of Paris Descartes, Institut Imagine, Centre de Reference des Mastocytoses, Paris, France.
Awan FT; Harold C. Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center, Dallas, Tex.
Hexner E; University of Pennsylvania, Philadelphia, Pa.
Mauro MJ; Memorial Sloan Kettering Cancer Center, New York, NY.
Menssen HD; Novartis Pharma AG, Basel, Switzerland.
Redhu S; Novartis Pharma AG, Basel, Switzerland.
Knoll S; Novartis Pharmaceuticals Corporation, East Hanover, NJ.
Sotlar K; Institute of Pathology, Paracelsus Medical University Salzburg, Austria.
George TI; University of Utah and ARUP Laboratories, Salt Lake City, Utah.
Horny HP; Ludwig-Maximilians-University Munich, Munich, Germany.
Valent P; Department of Internal Medicine I, Division of Hematology and Hemostaseology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
Reiter A; Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Kluin-Nelemans HC; University Medical Center Groningen, Department of Hematology, University of Groningen, Groningen, The Netherlands.
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2020 Aug; Vol. 146 (2), pp. 356-366.e4. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mastocytosis, Systemic/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Staurosporine/*analogs & derivatives
Adult ; Aged ; Aged, 80 and over ; Disease Progression ; Female ; Humans ; Male ; Mast Cells/pathology ; Middle Aged ; Quality of Life ; Staurosporine/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma.
Autorzy :
Stemler J; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany.
Koehler P; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Maurer C; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.
Müller C; Centre of Pharmacology, Therapeutic Drug Monitoring, Faculty of Medicine, Cologne, University Hospital of Cologne, Cologne, Germany.
Cornely OA; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany. .; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany. .; German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany. .; Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Cologne, Germany. .
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Źródło :
Annals of hematology [Ann Hematol] 2020 Jul; Vol. 99 (7), pp. 1429-1440. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antifungal Agents/*therapeutic use
Chemoprevention/*trends
Invasive Fungal Infections/*prevention & control
Leukemia, Myeloid, Acute/*drug therapy
Staurosporine/*analogs & derivatives
Triazoles/*therapeutic use
Antifungal Agents/classification ; Chemoprevention/methods ; Drug Interactions ; Drugs, Investigational/therapeutic use ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/microbiology ; Leukemia, Myeloid, Acute/mortality ; Prognosis ; Staurosporine/therapeutic use
Czasopismo naukowe
Tytuł :
Systematic response of staurosporine scaffold-based inhibitors to drug-resistant cancer kinase mutations.
Autorzy :
He Y; Department of Infectious Diseases, Taixing People's Hospital, Yangzhou University, Taixing, China.
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Źródło :
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2020 Jun; Vol. 353 (6), pp. e1900320. Date of Electronic Publication: 2020 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Neoplasms/*drug therapy
Protein Kinase Inhibitors/*pharmacology
Protein Kinases/*metabolism
Staurosporine/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Mutation ; Neoplasms/metabolism ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Protein Kinases/genetics ; Staurosporine/chemical synthesis ; Staurosporine/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Pancytopenia, eosinophilia and coagulation disorders in a patient with T-acute lymphoblastic leukemia in prolonged remission.
Autorzy :
Chatzidimitriou C; Department of Haematology and Bone Marrow Transplantation, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Pappa V; Second Propaedeutic Department of Internal Medicine and Research Institute, Hematology Unit, National and Kapodistrian University of Athens, Attikon General Hospital, Athens, Greece.
Lakiotaki E; First Department of Pathology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Plata E; Department of Haematology and Bone Marrow Transplantation, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Lafioniatis S; Haematology Unit, 'Achillopoulion' Hospital, Volos, Greece.
Angelopoulou MK; Department of Haematology and Bone Marrow Transplantation, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Konstantopoulos K; Department of Haematology and Bone Marrow Transplantation, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Korkolopoulou P; First Department of Pathology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Vassilakopoulos TP; Department of Haematology and Bone Marrow Transplantation, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
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Źródło :
American journal of hematology [Am J Hematol] 2021 May 01; Vol. 96 (5), pp. 632-637. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Eosinophilia/*etiology
Hemorrhagic Disorders/*etiology
Mastocytosis, Systemic/*blood
Neoplasms, Second Primary/*blood
Pancytopenia/*etiology
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*complications
Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Azacitidine/administration & dosage ; Azacitidine/therapeutic use ; Biomarkers, Tumor/blood ; Blood Cell Count ; Bone Marrow/pathology ; Cancer Survivors ; Chromosome Deletion ; Chromosome Disorders/pathology ; Chromosomes, Human, Pair 7 ; Diagnosis, Differential ; Eosinophilia/blood ; Hemorrhagic Disorders/blood ; Humans ; Interferon-alpha/therapeutic use ; Leukemia, Myeloid, Acute/pathology ; Male ; Mastocytosis, Systemic/complications ; Mastocytosis, Systemic/diagnosis ; Mastocytosis, Systemic/drug therapy ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/pathology ; Neoplasms, Second Primary/diagnosis ; Neoplasms, Second Primary/drug therapy ; Pancytopenia/blood ; Staurosporine/administration & dosage ; Staurosporine/analogs & derivatives ; Tryptases/blood
SCR Disease Name :
Monosomy 7 of Bone Marrow
Czasopismo naukowe
Tytuł :
Cost-effectiveness of midostaurin in the treatment of newly diagnosed FLT3-mutated acute myeloid leukemia in France.
Autorzy :
Tremblay G; Purple Squirrel Economics, New York, USA.
Cariou C; Novartis Pharmaceuticals, Rueil-Malmaison, France.
Recher C; Service d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole-Centre Hospitalier Université de Toulouse, Toulouse, France.
Dolph M; Purple Squirrel Economics, New York, USA.
Brandt P; Novartis Pharmaceuticals, East Hanover, USA.
Blanc AS; Novartis Pharmaceuticals, Rueil-Malmaison, France.
Forsythe A; Purple Squirrel Economics, New York, USA. .
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Źródło :
The European journal of health economics : HEPAC : health economics in prevention and care [Eur J Health Econ] 2020 Jun; Vol. 21 (4), pp. 543-555. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*economics
Antineoplastic Agents/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Staurosporine/*analogs & derivatives
Antineoplastic Combined Chemotherapy Protocols/economics ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cost-Benefit Analysis ; France ; Health Expenditures/statistics & numerical data ; Hematopoietic Stem Cell Transplantation/economics ; Hematopoietic Stem Cell Transplantation/statistics & numerical data ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/mortality ; Models, Econometric ; Quality-Adjusted Life Years ; Recurrence ; Remission Induction ; Staurosporine/adverse effects ; Staurosporine/economics ; Staurosporine/therapeutic use ; fms-Like Tyrosine Kinase 3/genetics
Czasopismo naukowe
Tytuł :
Midostaurin and cyclosporine drug interaction: A case report.
Autorzy :
Mancini R; St. Luke's Mountain States Tumor Institute, Boise, Idaho.
LaMontagne L; St. Luke's Mountain States Tumor Institute, Boise, Idaho.
Williams T; St. Luke's Mountain States Tumor Institute, Boise, Idaho.
Kreisle W; St. Luke's Mountain States Tumor Institute, Boise, Idaho.
Petersen F; St. Luke's Mountain States Tumor Institute, Boise, Idaho.
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Źródło :
Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2020 Apr; Vol. 45 (2), pp. 384-387. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji :
Case Reports
MeSH Terms :
Cyclosporine/*pharmacokinetics
Hematopoietic Stem Cell Transplantation/*methods
Immunosuppressive Agents/*pharmacokinetics
Staurosporine/*analogs & derivatives
Aged ; Calcineurin Inhibitors/administration & dosage ; Calcineurin Inhibitors/pharmacokinetics ; Cyclosporine/administration & dosage ; Drug Interactions ; Humans ; Immunosuppressive Agents/administration & dosage ; Male ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/pharmacology ; Staurosporine/administration & dosage ; Staurosporine/pharmacology
Raport
Tytuł :
Systematic profiling of staralog response to acquired drug resistant kinase gatekeeper mutations in targeted cancer therapy.
Autorzy :
Yang Y; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, 453003, China.
Qiu Y; College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China.
Liu X; College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China.
Liu Y; College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China.
Yin Y; College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China. .
Li P; College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China. .
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Źródło :
Amino acids [Amino Acids] 2020 Apr; Vol. 52 (4), pp. 511-521. Date of Electronic Publication: 2020 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Targeted Therapy*
Antineoplastic Agents/*pharmacology
Drug Resistance, Neoplasm/*genetics
Protein Kinase Inhibitors/*pharmacology
Staurosporine/*pharmacology
Antineoplastic Agents/therapeutic use ; Crystallography, X-Ray ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/chemistry ; ErbB Receptors/genetics ; Humans ; Mutation ; Neoplasms/drug therapy ; Protein Conformation ; Protein Kinase Inhibitors/therapeutic use ; Staurosporine/chemistry ; Staurosporine/therapeutic use
Czasopismo naukowe
Tytuł :
Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis.
Autorzy :
Ye G; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Yang Q; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Lei X; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Zhu X; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Present address: Department of General Surgery, Panyu Central Hospital, Guangzhou, Guangdong 511400, China.
Li F; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
He J; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Chen H; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Ling R; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Zhang H; Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Lin T; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Liang Z; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Liang Y; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Huang H; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Guo W; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Deng H; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Liu H; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Hu Y; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Yu J; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
Li G; Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangdong Provincial Engineering Technology Research Center of Minimally Invasive Surgery, Guangzhou, Guangdong 510515, China.; Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Guangzhou, Guangdong 510515, China.
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Źródło :
Theranostics [Theranostics] 2020 Jun 12; Vol. 10 (17), pp. 7545-7560. Date of Electronic Publication: 2020 Jun 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anoikis/*genetics
Lung Neoplasms/*genetics
Myosin Heavy Chains/*metabolism
Staurosporine/*pharmacology
Stomach Neoplasms/*pathology
beta Catenin/*genetics
Animals ; Anoikis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Movement/genetics ; Cell Nucleus/metabolism ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Chemotherapy, Adjuvant/methods ; Female ; Gastrectomy ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Knockdown Techniques ; Humans ; Lung Neoplasms/prevention & control ; Lung Neoplasms/secondary ; Male ; Mice ; Mice, Transgenic ; Myosin Heavy Chains/genetics ; Phosphorylation/drug effects ; Promoter Regions, Genetic/genetics ; Staurosporine/therapeutic use ; Stomach/pathology ; Stomach/surgery ; Stomach Neoplasms/genetics ; Stomach Neoplasms/therapy ; Transcriptional Activation/drug effects ; Up-Regulation/drug effects ; Wnt Signaling Pathway/drug effects ; Wnt Signaling Pathway/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Inhibition of human UDP-glucuronosyltransferase enzymes by midostaurin and ruxolitinib: implications for drug-drug interactions.
Autorzy :
Wang Z; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
Wang X; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
Jia Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
Yin H; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
Feng Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
Jiang L; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
Cao J; Department of Occupational and Environmental Health, Dalian Medical University, Dalian, 116044, China.
Liu Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, China.
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Źródło :
Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2020 Jun; Vol. 41 (6), pp. 231-238. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Glucuronosyltransferase/*antagonists & inhibitors
Isoenzymes/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Pyrazoles/*pharmacology
Staurosporine/*analogs & derivatives
Drug Interactions ; Humans ; Recombinant Proteins ; Staurosporine/pharmacology
Czasopismo naukowe
Tytuł :
CCL5 mediates target-kinase independent resistance to FLT3 inhibitors in FLT3-ITD-positive AML.
Autorzy :
Waldeck S; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.; Faculty of Biology, University of Freiburg, Germany.; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Rassner M; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Keye P; Department of Ophthalmology, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Follo M; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Herchenbach D; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Endres C; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Charlet A; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Andrieux G; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Medical Bioinformatics and Systems Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Salzer U; Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Germany.; Department of Rheumatology and Clinical Immunology, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Boerries M; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Medical Bioinformatics and Systems Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Duyster J; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.
von Bubnoff N; Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Hematology and Oncology, Medical Center, University of Schleswig Holstein, Lübeck, Germany.
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Źródło :
Molecular oncology [Mol Oncol] 2020 Apr; Vol. 14 (4), pp. 779-794. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
Chemokine CCL5/*genetics
Leukemia, Myeloid, Acute/*drug therapy
Protein Kinase Inhibitors/*pharmacology
Staurosporine/*analogs & derivatives
fms-Like Tyrosine Kinase 3/*genetics
Cell Line, Tumor ; Chemokine CCL5/metabolism ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; Mutation/drug effects ; Staurosporine/pharmacology ; Up-Regulation/drug effects ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.
Autorzy :
Griffiths EA; Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY, USA. Electronic address: .
Carraway HE; Taussig Cancer Institute, Cleveland Clinic, 10900 Euclid Ave, Cleveland, OH, USA. Electronic address: .
Chandhok NS; University of Miami, Coral Gables, FL, USA. Electronic address: .
Prebet T; Smilow Cancer Center at Yale New Haven Hospital, 35 Park Street, New Haven, CT, USA. Electronic address: .
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Źródło :
Leukemia research [Leuk Res] 2020 Apr; Vol. 91, pp. 106339. Date of Electronic Publication: 2020 Feb 26.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Azacitidine/*therapeutic use
Decitabine/*therapeutic use
Gemtuzumab/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Staurosporine/*analogs & derivatives
Aged ; Benzimidazoles/therapeutic use ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Cytarabine/therapeutic use ; Glycine/analogs & derivatives ; Glycine/therapeutic use ; Humans ; Leukemia, Myeloid, Acute/pathology ; Male ; Molecular Targeted Therapy/methods ; Phenylurea Compounds/therapeutic use ; Precision Medicine ; Pyridines/therapeutic use ; Recurrence ; Remission Induction ; Staurosporine/therapeutic use ; Sulfonamides/therapeutic use
Czasopismo naukowe
Tytuł :
Specific, reversible G1 arrest by UCN-01 in vivo provides cytostatic protection of normal cells against cytotoxic chemotherapy in breast cancer.
Autorzy :
Mull BB; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Livingston JA; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Patel N; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Bui T; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Hunt KK; Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Keyomarsi K; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. .
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Źródło :
British journal of cancer [Br J Cancer] 2020 Mar; Vol. 122 (6), pp. 812-822. Date of Electronic Publication: 2020 Jan 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Breast Neoplasms/*drug therapy
Breast Neoplasms/*genetics
Cytostatic Agents/*therapeutic use
G1 Phase/*drug effects
Staurosporine/*analogs & derivatives
Animals ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/pathology ; Cytostatic Agents/pharmacology ; Female ; Humans ; Mice ; Mice, Nude ; Staurosporine/pharmacology ; Staurosporine/therapeutic use
Czasopismo naukowe
Tytuł :
Pregnancy exposure to midostaurin in the first trimester.
Autorzy :
Ojha S; College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Ooi MG; Department of Haematology Oncology, National University Hospital, Singapore, Singapore. .
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Źródło :
Annals of hematology [Ann Hematol] 2020 Feb; Vol. 99 (2), pp. 355-356. Date of Electronic Publication: 2020 Jan 03.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Fetal Growth Retardation/*etiology
Infant, Premature, Diseases/*etiology
Leukemia, Myeloid, Acute/*drug therapy
Pregnancy Complications, Neoplastic/*drug therapy
Pregnancy Trimester, First/*drug effects
Protein Kinase Inhibitors/*adverse effects
Staurosporine/*analogs & derivatives
Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cesarean Section ; Compassionate Use Trials ; Cytarabine/administration & dosage ; Female ; Fetal Growth Retardation/chemically induced ; Humans ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases/chemically induced ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/physiopathology ; Mutation ; Pregnancy ; Pregnancy Complications, Neoplastic/genetics ; Pregnancy Outcome ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/pharmacology ; Recurrence ; Staurosporine/administration & dosage ; Staurosporine/adverse effects ; Staurosporine/pharmacology ; Tandem Repeat Sequences ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors ; fms-Like Tyrosine Kinase 3/genetics
Raport
Tytuł :
Necrotizing Hemorrhagic Gastritis following Acute Myeloid Leukemia Induction with Midostaurin: An Unexpected Complication.
Autorzy :
Shimony S; Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel, .; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, .
Reiss Mintz H; Division of Gastroenterology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Shvartser Beryozkin Y; Division of Pathology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Shoham A; Radiology Department, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
Raanani P; Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Wolach O; Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło :
Acta haematologica [Acta Haematol] 2020; Vol. 143 (1), pp. 65-68. Date of Electronic Publication: 2019 Jul 10.
Typ publikacji :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastritis/*etiology
Leukemia, Myeloid, Acute/*drug therapy
Protein Kinase Inhibitors/*adverse effects
Staurosporine/*analogs & derivatives
Abdominal Pain/etiology ; Gastritis/pathology ; Humans ; Male ; Middle Aged ; Protein Kinase Inhibitors/therapeutic use ; Remission Induction ; Staurosporine/adverse effects ; Staurosporine/therapeutic use ; Tomography, X-Ray Computed
Raport
Tytuł :
Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors.
Autorzy :
Shomali W; Division of Hematology, School of Medicine, Stanford Cancer Institute/Stanford University, 875 Blake Wilbur Drive, Stanford, CA 94305-6555, USA.
Gotlib J; Division of Hematology, School of Medicine, Stanford Cancer Institute/Stanford University, 875 Blake Wilbur Drive, Stanford, CA 94305-6555, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 15; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Proliferation/*genetics
Mastocytosis, Systemic/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Proto-Oncogene Proteins c-kit/*genetics
Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Mast Cells/drug effects ; Mast Cells/pathology ; Mastocytosis, Systemic/genetics ; Mastocytosis, Systemic/pathology ; Pyrazoles/therapeutic use ; Pyrroles/therapeutic use ; Staurosporine/analogs & derivatives ; Staurosporine/therapeutic use ; Triazines/therapeutic use
Czasopismo naukowe
Tytuł :
Effects of the multi-kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia.
Autorzy :
Weisberg E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Meng C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Case AE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Tiv HL; Experimental Therapeutic Core, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Gokhale PC; Experimental Therapeutic Core, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Buhrlage SJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Yang J; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Liu X; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Wang J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Gray N; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Adamia S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Sattler M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Stone R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Griffin JD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Mar; Vol. 24 (5), pp. 2968-2980. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Leukemia, Myeloid, Acute/*drug therapy
Protein Kinase Inhibitors/*pharmacology
Staurosporine/*analogs & derivatives
fms-Like Tyrosine Kinase 3/*genetics
Aniline Compounds/pharmacology ; Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Benzimidazoles/pharmacology ; Benzothiazoles/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Mice ; Mutation/drug effects ; Phenylurea Compounds/pharmacology ; Piperidines/pharmacology ; Pyrazines/pharmacology ; Sorafenib/pharmacology ; Staurosporine/pharmacology ; Syk Kinase/genetics ; fms-Like Tyrosine Kinase 3/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Solvent-Induced Protein Precipitation for Drug Target Discovery on the Proteomic Scale.
Autorzy :
Zhang X; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, National Engineering Laboratory of AIDS Vaccine, School of Life Sciences , Jilin University , Changchun 130012 , China.; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , China.
Wang Q; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , China.
Li Y; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , China.
Ruan C; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , China.
Wang S; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, National Engineering Laboratory of AIDS Vaccine, School of Life Sciences , Jilin University , Changchun 130012 , China.; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , China.
Hu L; Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, National Engineering Laboratory of AIDS Vaccine, School of Life Sciences , Jilin University , Changchun 130012 , China.
Ye M; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023 , China.
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Źródło :
Analytical chemistry [Anal Chem] 2020 Jan 07; Vol. 92 (1), pp. 1363-1371. Date of Electronic Publication: 2019 Dec 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteomics*
HSP90 Heat-Shock Proteins/*antagonists & inhibitors
Methotrexate/*pharmacology
NADH Dehydrogenase/*antagonists & inhibitors
Oxazoles/*pharmacology
Staurosporine/*pharmacology
Thiazoles/*pharmacology
Acetic Acid/chemistry ; Acetone/chemistry ; Cells, Cultured ; Drug Discovery ; Drug Evaluation, Preclinical ; Ethanol/chemistry ; HEK293 Cells ; HSP90 Heat-Shock Proteins/chemistry ; HeLa Cells ; High-Throughput Screening Assays ; Humans ; Methotrexate/chemistry ; NADH Dehydrogenase/chemistry ; NADH Dehydrogenase/metabolism ; Oxazoles/chemistry ; Solvents/chemistry ; Staurosporine/chemistry ; Thiazoles/chemistry
Czasopismo naukowe

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