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Tytuł :
Humoral and cellular immunity to SARS-CoV-2 vaccination in renal transplant versus dialysis patients: A prospective, multicenter observational study using mRNA-1273 or BNT162b2 mRNA vaccine.
Autorzy :
Stumpf J; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; KfH-Nierenzentrum Dresden, Dresden, Germany.
Siepmann T; KfH-Nierenzentrum am Klinikum Chemnitz, Krankenhaus Küchwald, Chemnitz, Germany.
Lindner T; Division of Nephrology, University Hospital Leipzig, Leipzig, Germany.
Karger C; KfH-Nierenzentrum am Klinikum St. Georg, Leipzig, Germany.
Schwöbel J; Dialysezenturm Chemnitz, Chemnitz, Germany.
Anders L; Dialysepraxis Leipzig, Leipzig, Germany.
Faulhaber-Walter R; Nephrologisches Zentrum Freiberg, Freiberg, Germany.
Schewe J; Dialyse- und Nierenambulanz Sebnitz, Sebnitz, Germany.
Martin H; Nephrologisches Zentrum Zwickau, Zwickau, Germany.
Schirutschke H; PHV Dialysezentrum Dresden Friedrichstadt, Dresden, Germany.
Barnett K; Dialyse Heidenau, Heidenau, Germany.
Hüther J; Nephrocare GmbH Döbeln, Döbeln, Germany.
Müller P; PHV Dialysezentrum Dresden-Johannstadt, Dresden, Germany.
Langer T; Dialysezentrum Annaberg, Annaberg-Buchholz, Germany.
Pluntke T; KfH-Nierenzentrum Grimma, Grimma, Germany.
Anding-Rost K; KfH-Nierenzentrum Bischofswerda, Bischofswerda, Germany.
Meistring F; KfH-Nierenzentrum am Städtischen Klinikum Görlitz, Görlitz, Germany.
Stehr T; KfH-Nierenzentrum Bautzen, Bautzen, Germany.
Pietzonka A; Via medis Nierenzentrum Dresden MVZ GmbH, Dresden, Germany.
Escher K; KfH-Gesundheitszentrum Aue, Aue-Bad-Schlema, Germany.
Cerny S; ELBLAND Dialyse Großenhain, Großenhain, Germany.
Rothe H; Dialyse-Praxis Weißwasser, Weißwasser, Germany.
Pistrosch F; Nephrologisches Zentrum Hoyerswerda, Hoyerswerda, Germany.
Seidel H; KfH-Nierenzentrum am Vogtland Krankenhaus Plauen, Plauen, Germany.
Paliege A; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Beige J; KfH-Nierenzentrum am Klinikum St. Georg, Leipzig, Germany.; Department of Nephrology und Rheumatology, Internal Medicine II, Martin-Luther-University Halle/Wittenberg, Halle, Germany.
Bast I; Dialysepraxis Leipzig, Leipzig, Germany.
Steglich A; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Gembardt F; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Kessel F; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Kröger H; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Arndt P; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Sradnick J; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Frank K; Institut für Transfusionsmedizin Plauen, DRK-Blutspendedienst Nord-Ost gemeinnützige GmbH, Plauen, Germany.
Klimova A; National Center for Tumor Diseases (NCT) Partner Site Dresden, Dresden, Germany.
Mauer R; Faculty of Medicine Carl Gustav Carus, Institute for Medical Informatics and Biometry (IMB), Technische Universität, Dresden, Germany.
Grählert X; Coordinating Centre for Clinical Trials, Dresden, Germany.
Anft M; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Germany.
Blazquez-Navarro A; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Germany.
Westhoff TH; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Stervbo U; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Germany.
Tonn T; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East, Dresden, Germany.; Faculty of Medicine Carl Gustav Carus, Transfusion Medicine, Technische Universität, Dresden, Germany.
Babel N; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, and Institute of Medical Immunology, Germany.
Hugo C; Medizinische Klinik und Poliklinik III, Universitätsklinikum, Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; KfH-Nierenzentrum Dresden, Dresden, Germany.
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Źródło :
The Lancet regional health. Europe [Lancet Reg Health Eur] 2021 Jul 23, pp. 100178. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Correspondence on 'SARS-CoV-2 vaccination in rituximab-treated patients: evidence for impaired humoral but inducible cellular immune response'.
Autorzy :
Westhoff TH; Medical Department I, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.
Seibert FS; Medical Department I, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.
Anft M; Immundiagnostik, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Center for Translational Medicine, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.
Blazquez-Navarro A; Immundiagnostik, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Center for Translational Medicine, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Skrzypczyk S; Immundiagnostik, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Center for Translational Medicine, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.
Doevelaar A; Medical Department I, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.
Hölzer B; Medical Department I, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.
Paniskaki K; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Dolff S; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Wilde B; Department of Nephrology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Witzke O; Department of Nephrology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Braun J; Rheumazentrum Ruhrgebiet, University Hospital of the Ruhr University Bochum, Herne, Germany.
Stervbo U; Immundiagnostik, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Center for Translational Medicine, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Babel N; Immundiagnostik, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany .; Center for Translational Medicine, Marien Hospital Herne - University Hospital of the Ruhr-University Bochum, Herne, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Jul 16. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Superior cellular and humoral immunity toward SARS-CoV-2 reference and alpha and beta VOC strains in COVID-19 convalescent as compared to the prime boost BNT162b2-vaccinated dialysis patients.
Autorzy :
Blazquez-Navarro A; Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Safi L; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Meister TL; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Thieme CJ; Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Kaliszczyk S; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Paniskaki K; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Stockhausen M; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Hörstrup J; Berlin Department, KfH Kuratorium für Dialyse und Nierentransplantation e.V., Berlin, Germany.
Cinkilic O; Dialyse Schwerte, Schwerte, Germany.
Flitsch-Kiefner L; Hagen Department, KfH Kuratorium für Dialyse und Nierentransplantation e.V., Hagen, Germany.
Marheinecke C; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Steinmann E; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Seibert FS; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Stervbo U; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Westhoff TH; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Pfaender S; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Roch T; Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Babel N; Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany. Electronic address: .
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Źródło :
Kidney international [Kidney Int] 2021 Jul 14. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Detection of pre-existing SARS-CoV-2-reactive T cells in unexposed renal transplant patients.
Autorzy :
Anft M; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Blazquez-Navarro A; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Charitéplatz 1, 10117, Berlin, Germany.
Stervbo U; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Skrzypczyk S; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Witzke O; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147, Essen, Germany.
Wirth R; Department of Geriatrics, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Choi M; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Charitéplatz 1, 10117, Berlin, Germany.
Hugo C; Department of Nephrology, Medical Department III, Universitätsklinikum Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Reinke P; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Charitéplatz 1, 10117, Berlin, Germany.
Meister TL; Department of Molecular and Medical Virology, Ruhr University Bochum, Universitätsstrasse 50, 44801, Bochum, Germany.
Steinmann E; Department of Molecular and Medical Virology, Ruhr University Bochum, Universitätsstrasse 50, 44801, Bochum, Germany.
Pfaender S; Department of Molecular and Medical Virology, Ruhr University Bochum, Universitätsstrasse 50, 44801, Bochum, Germany.
Schenker P; Department Surgery, Knappschaftskrankenhaus Bochum, University Hospital of the Ruhr-University Bochum, In der Schornau 23, 44892, Bochum, Germany.
Viebahn R; Department Surgery, Knappschaftskrankenhaus Bochum, University Hospital of the Ruhr-University Bochum, In der Schornau 23, 44892, Bochum, Germany.
Westhoff TH; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Babel N; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany. .; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Charitéplatz 1, 10117, Berlin, Germany. .
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Źródło :
Journal of nephrology [J Nephrol] 2021 Jul 06. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The impact of acute diarrhea on the coagulation status of patients with vitamin K antagonists.
Autorzy :
Schweinfurth J; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Bauer A; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Bauer F; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Seibert FS; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Rohn B; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Seidel M; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Bertram S; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Stervbo U; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Babel N; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Westhoff TH; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jun 03; Vol. 11 (1), pp. 11726. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
SARS-CoV-2-reactive cellular and humoral immunity in hemodialysis population.
Autorzy :
Anft M; Center for Translational Medicine and Immune Diagnostics Laboratory, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Blazquez-Navarro A; Center for Translational Medicine and Immune Diagnostics Laboratory, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany.
Paniskaki K; Center for Translational Medicine and Immune Diagnostics Laboratory, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Skrzypczyk S; Center for Translational Medicine and Immune Diagnostics Laboratory, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Appel H; Dialysezentrum Hamm, Hamm, Germany.
Pfab T; Diaverum Medizinisches Versorgungszentrum Am Neuen Garten, Potsdam, Germany.
Uhle A; Dialyse am Kortumpark, Bochum, Germany.
Frahnert M; Dialyse Bochum, Bochum, Germany.
Barenbrock M; Dialysezentrum Hamm, Hamm, Germany.
Büssemaker E; Dialysezentrum Hamm, Hamm, Germany.
Hörstrup J; KfH Kuratorium für Dialyse und Nierentransplantation e.V. KfH-Nierenzentrum, Berlin, Germany.
Doevelaar A; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Seibert FS; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Hölzer B; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Stervbo U; Center for Translational Medicine and Immune Diagnostics Laboratory, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany.
Dolff S; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Witzke O; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Babel N; Center for Translational Medicine and Immune Diagnostics Laboratory, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany. Electronic address: .
Westhoff TH; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
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Źródło :
Kidney international [Kidney Int] 2021 Jun; Vol. 99 (6), pp. 1489-1490. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Letter
MeSH Terms :
COVID-19*
Immunity, Humoral*
Antibodies, Viral ; Humans ; Immunity, Cellular ; Renal Dialysis/adverse effects ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
Opinia redakcyjna
Tytuł :
Rapid T cell receptor interaction grouping with ting.
Autorzy :
Mölder F; Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, 45147 Essen, Germany.; Institute of Pathology, University of Duisburg-Essen, 45147, Germany.
Stervbo U; Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, Ruhr-University Bochum, 44623 Herne, Germany.
Loyal L; Si-M/'Der Simulierte Mensch' a science framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, 13353 Berlin, Germany.; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Bacher P; Institute of Immunology, Christian-Albrechts Universität zu Kiel and Universitätsklinik Schleswig-Holstein, Kiel, Germany.; Institute of Clinical Molecular Biology, Christian-Albrechts Universität zu Kiel, Kiel, Germany.
Babel N; Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, Ruhr-University Bochum, 44623 Herne, Germany.; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, 13353 Berlin, Germany.; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Rahmann S; Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, 45147 Essen, Germany.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 May 13. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Generation of HBsAg-reactive T- and B-cells following HBV vaccination in serological non-responders under hemodialysis treatment.
Autorzy :
Roch T; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Giesecke-Thiel C; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Deutsches Rheuma-Forschungszentrum (DRFZ), Berlin, Germany.
Blazquez-Navarro A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Wehler P; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Thieme CJ; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Juelke K; BIH Center for Regenerative Therapies (BCRT) Charité - Universitätsmedizin Berlin Inst. f. Med. Immunologie Immunologisches Studienlabor (ISL) - Biomarker, Germany.
Grütz G; BIH Center for Regenerative Therapies (BCRT) Charité - Universitätsmedizin Berlin Inst. f. Med. Immunologie Immunologisches Studienlabor (ISL) - Biomarker, Germany.
Hörstrup J; KfH Nierenzentrum Berlin-Charlottenburg, Berlin, Germany.
Witzke O; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Germany.
Dittmer U; Institute for Virology, Universitätsklinikum of University Duisburg-Essen, Essen, Germany.
Stervbo U; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Reinke P; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Westhoff TH; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Babel N; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Center for Translational Medicine, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
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Źródło :
European journal of immunology [Eur J Immunol] 2021 May; Vol. 51 (5), pp. 1278-1281. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Immune monitoring facilitates the clinical decision in multifocal COVID-19 of a pancreas-kidney transplant patient.
Autorzy :
Babel N; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Anft M; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Blazquez-Navarro A; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Doevelaar AAN; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Seibert FS; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Bauer F; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Rohn BJ; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Hoelzer B; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Thieme CJ; Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Roch T; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Meister TL; Department of Molecular and Medical Virology, Ruhr-University, Bochum, Germany.
Pfaender S; Department of Molecular and Medical Virology, Ruhr-University, Bochum, Germany.
Steinmann E; Department of Molecular and Medical Virology, Ruhr-University, Bochum, Germany.
Dittmer U; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Schenker P; Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University, Bochum, Germany.
Amann K; Department of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Germany.
Viebahn R; Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University, Bochum, Germany.
Stervbo U; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Westhoff TH; Medical Department, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
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Źródło :
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2020 Nov; Vol. 20 (11), pp. 3210-3215. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Humoral*
Kidney Transplantation*
Antibodies, Viral/*immunology
COVID-19/*epidemiology
Monitoring, Immunologic/*methods
Pancreas Transplantation/*methods
SARS-CoV-2/*immunology
COVID-19/virology ; Clinical Decision-Making ; Comorbidity ; Graft Rejection/epidemiology ; Graft Rejection/immunology ; Humans ; Immunocompromised Host ; Pandemics
Raport
Tytuł :
Detection of SARS-CoV-2-specific memory B cells to delineate long-term COVID-19 immunity.
Autorzy :
Thieme CJ; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.
Abou-El-Enein M; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.; Division of Medical Oncology, Department of Medicine, and Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Joint USC/CHLA Cell Therapy Program, University of Southern California, and Children's Hospital Los Angeles, Los Angeles, CA, USA.
Fritsche E; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.
Anft M; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Paniskaki K; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Skrzypczyk S; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Doevelaar A; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Elsallab M; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.; Joint USC/CHLA Cell Therapy Program, University of Southern California, and Children's Hospital Los Angeles, Los Angeles, CA, USA.
Brindle N; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.
Blazquez-Navarro A; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Seibert FS; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Meister TL; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Pfaender S; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Steinmann E; Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.
Witzke O; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Westhoff TH; Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Stervbo U; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Heine G; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany.
Roch T; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
Babel N; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), and Institute of Medical Immunology, Berlin, Germany.; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Herne, Germany.
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Źródło :
Allergy [Allergy] 2021 Aug; Vol. 76 (8), pp. 2595-2599. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*
SARS-CoV-2*
B-Lymphocytes ; Humans ; Immunologic Memory ; Spike Glycoprotein, Coronavirus
Raport
Tytuł :
Robust hepatitis B vaccine-reactive T cell responses in failed humoral immunity.
Autorzy :
Awad G; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.
Roch T; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.; BIH Center for Regenerative Therapies, Charité - University Medicine Berlin, corporate member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany.
Stervbo U; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.
Kaliszczyk S; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.; BIH Center for Regenerative Therapies, Charité - University Medicine Berlin, corporate member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany.
Stittrich A; BIH Center for Regenerative Therapies, Charité - University Medicine Berlin, corporate member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany.; Labor Berlin - Charité Vivantes GmbH, Berlin, Germany.
Hörstrup J; KfH Kuratorium für Dialyse und Nierentransplantation e.V., Berlin, Germany.
Cinkilic O; Dialyse Schwerte, Schwerte, Germany.
Appel H; Dialysezentrum Hamm, Hamm, Germany.
Natrus L; Bogomolets National Medical University, Kyiv, Ukraine.
Gayova L; Bogomolets National Medical University, Kyiv, Ukraine.
Seibert F; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.
Bauer F; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.
Westhoff T; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.
Nienen M; BIH Center for Regenerative Therapies, Charité - University Medicine Berlin, corporate member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany.; Labor Berlin - Charité Vivantes GmbH, Berlin, Germany.; Institute for Medical Immunology, Charité - University Medicine Berlin, corporate member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany.
Babel N; University Hospital Marien Hospital Herne, Ruhr-University of Bochum, Bochum, Germany.; BIH Center for Regenerative Therapies, Charité - University Medicine Berlin, corporate member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany.
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Źródło :
Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2021 Mar 23; Vol. 21, pp. 288-298. Date of Electronic Publication: 2021 Mar 23 (Print Publication: 2021).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The Magnitude and Functionality of SARS-CoV-2 Reactive Cellular and Humoral Immunity in Transplant Population Is Similar to the General Population Despite Immunosuppression.
Autorzy :
Thieme CJ; 1Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Germany 2Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Germany 3Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Germany 4Department of Anesthesiology, University Hospital Essen, University Duisburg-Essen, Germany 5Department of Immunology, Labor Berlin GmbH, Berlin, Germany 6Ruhr-University Bochum, University Hospital Knappschaftskrankenhaus Bochum, Department of Surgery, Bochum, Germany.
Anft M
Paniskaki K
Blazquez-Navarro A
Doevelaar A
Seibert FS
Hoelzer B
Konik MJ
Meister TL
Pfaender S
Steinmann E
Berger MM
Brenner T
Kölsch U
Dolff S
Roch T
Witzke O
Schenker P
Viebahn R
Stervbo U
Westhoff TH
Babel N
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Źródło :
Transplantation [Transplantation] 2021 Mar 18. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The intratumoral CXCR3 chemokine system is predictive of chemotherapy response in human bladder cancer.
Autorzy :
Vollmer T; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Schlickeiser S; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Amini L; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Schulenberg S; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Wendering DJ; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Banday V; Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, 901 85 Umea, Sweden.; Department of Clinical Microbiology, Immunology, Umea University, 901 85 Umea, Sweden.
Jurisch A; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Noster R; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Kunkel D; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Brindle NR; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Savidis I; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Akyüz L; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Hecht J; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.; Universitat Pompeu Fabra (UPF), 08002 Barcelona, Spain.
Stervbo U; Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, D-44623 Herne, Germany.
Roch T; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, D-44623 Herne, Germany.
Babel N; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Center for Translational Medicine, Medical Clinic I, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, D-44623 Herne, Germany.
Reinke P; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Winqvist O; Department of Clinical Immunology, Karolinska University Hospital, 17 176 Stockholm, Sweden.
Sherif A; Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, 901 85 Umea, Sweden.
Volk HD; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
Schmueck-Henneresse M; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany. .; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.; Berlin Center for Advanced Therapies (BeCAT), Charité - Universitätsmedizin Berlin, D-13353 Berlin, Germany.
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Źródło :
Science translational medicine [Sci Transl Med] 2021 Jan 13; Vol. 13 (576).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Urinary Bladder Neoplasms*/drug therapy
CD8-Positive T-Lymphocytes ; Chemokine CXCL10/therapeutic use ; Chemokine CXCL11/therapeutic use ; Chemokines ; Chemotherapy, Adjuvant ; Humans ; Neoadjuvant Therapy ; Receptors, CXCR3
Czasopismo naukowe
Tytuł :
Nuclear antigen-reactive CD4 T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys.
Autorzy :
Abdirama D; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany.
Tesch S; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany.
Grießbach AS; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany.
von Spee-Mayer C; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Humrich JY; Department of Rheumatology and Clinical Immunology, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany.
Stervbo U; Berlin-Brandenburg Centrum für Regenerative Therapie, Berlin, Germany; Centre for Translational Medicine, Universitätsklinikum der Ruhr-Universität Bochum, Bochum, Germany.
Babel N; Berlin-Brandenburg Centrum für Regenerative Therapie, Berlin, Germany; Centre for Translational Medicine, Universitätsklinikum der Ruhr-Universität Bochum, Bochum, Germany.
Meisel C; Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Labor Berlin - Charité Vivantes GmbH, Berlin, Germany.
Alexander T; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Biesen R; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Bacher P; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany.
Scheffold A; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany.
Eckardt KU; Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Hiepe F; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Radbruch A; Deutsches Rheuma-Forschungszentrum, a Leibniz Institute, Berlin, Germany.
Burmester GR; Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Riemekasten G; Department of Rheumatology and Clinical Immunology, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany. Electronic address: .
Enghard P; Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address: .
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Źródło :
Kidney international [Kidney Int] 2021 Jan; Vol. 99 (1), pp. 238-246. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytokines*
Lupus Erythematosus, Systemic*
Antigens, Nuclear ; CD4-Positive T-Lymphocytes ; Humans ; Kidney
Czasopismo naukowe
Tytuł :
COVID-19-Induced ARDS Is Associated with Decreased Frequency of Activated Memory/Effector T Cells Expressing CD11a .
Autorzy :
Anft M; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Paniskaki K; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Blazquez-Navarro A; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Doevelaar A; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Seibert FS; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Hölzer B; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Skrzypczyk S; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Kohut E; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Kurek J; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Zapka J; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Wehler P; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Kaliszczyk S; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Bajda S; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Thieme CJ; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Roch T; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Konik MJ; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Berger MM; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Brenner T; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Kölsch U; Department of Immunology, Labor Berlin GmbH, Sylter Straße 2, 13353 Berlin, Germany.
Meister TL; Department of Molecular and Medical Virology, Ruhr-University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany.
Pfaender S; Department of Molecular and Medical Virology, Ruhr-University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany.
Steinmann E; Department of Molecular and Medical Virology, Ruhr-University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany.
Tempfer C; Department of Gynecology and Obstetrics, Marien Hospital Herne, University Hospital of the Ruhr-University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Watzl C; Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors at the Technical University Dortmund (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany.
Dolff S; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Dittmer U; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Abou-El-Enein M; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Berlin Center for Advanced Therapies (BeCAT), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Westhoff TH; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Witzke O; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Stervbo U; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany.
Babel N; Center for Translational Medicine and Immune Diagnostics Laboratory, Medical Department I, Marien Hospital Herne, University Hospital of the Ruhr University Bochum, Hölkeskampring 40, 44625 Herne, Germany; Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. Electronic address: .
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 Dec 02; Vol. 28 (12), pp. 2691-2702. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pandemics*
COVID-19/*immunology
Immunologic Memory/*immunology
Respiratory Distress Syndrome/*immunology
Adult ; Aged ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; COVID-19/virology ; Female ; Humans ; Male ; Membrane Glycoproteins/immunology ; Middle Aged ; Respiratory Distress Syndrome/pathology ; Respiratory Distress Syndrome/virology ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; T-Lymphocyte Subsets/immunology
Czasopismo naukowe
Tytuł :
Lessons for the clinical nephrologist: recurrence of nephrotic syndrome induced by SARS-CoV-2.
Autorzy :
Doevelaar AAN; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Hölzer B; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Seibert FS; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Bauer F; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Stervbo U; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Herne, Germany.
Rohn BJ; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Zgoura P; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.
Schenker P; Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, Bochum, Germany.
Vonbrunn E; Department of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Amann K; Department of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Viebahn R; Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, Bochum, Germany.
Babel N; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany.; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Herne, Germany.
Westhoff TH; Medical Department 1, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, 44625, Herne, Germany. .
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Źródło :
Journal of nephrology [J Nephrol] 2020 Dec; Vol. 33 (6), pp. 1369-1372. Date of Electronic Publication: 2020 Sep 05.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
COVID-19/*complications
Kidney Glomerulus/*pathology
Nephrologists/*standards
Nephrotic Syndrome/*etiology
Adult ; Biopsy ; COVID-19/epidemiology ; Humans ; Male ; Nephrotic Syndrome/diagnosis ; Pandemics ; Recurrence
Czasopismo naukowe
Tytuł :
Epitope similarity cannot explain the pre-formed T cell immunity towards structural SARS-CoV-2 proteins.
Autorzy :
Stervbo U; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany. ulrik.stervbo@elisabethgruppe.de.; Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany. ulrik.stervbo@elisabethgruppe.de.
Rahmann S; Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, Duisburg, Germany. .
Roch T; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
Westhoff TH; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.
Babel N; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University, Bochum, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, and Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 04; Vol. 10 (1), pp. 18995. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunologic Memory*
Coronavirus Infections/*immunology
Epitopes/*immunology
Pneumonia, Viral/*immunology
T-Lymphocytes/*immunology
Viral Structural Proteins/*immunology
Antigens, Viral/chemistry ; Antigens, Viral/immunology ; Betacoronavirus/immunology ; COVID-19 ; Epitopes/chemistry ; Humans ; Pandemics ; SARS-CoV-2 ; Viral Structural Proteins/chemistry
Czasopismo naukowe
Tytuł :
Allograft infiltration and meningoencephalitis by SARS-CoV-2 in a pancreas-kidney transplant recipient.
Autorzy :
Westhoff TH; Medical Department I, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Seibert FS; Medical Department I, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Bauer F; Medical Department I, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Stervbo U; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Anft M; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Doevelaar AAN; Medical Department I, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Rohn BJ; Medical Department I, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Winnekendonk G; Institute of Radiology, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
Dittmer U; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Schenker P; Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, Bochum, Germany.
Vonbrunn E; Department of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Amann K; Department of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Viebahn R; Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, Bochum, Germany.
Babel N; Medical Department I, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.; Center for Translational Medicine, University Hospital Marien Hospital Herne, Ruhr-University Bochum, Bochum, Germany.
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Źródło :
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2020 Nov; Vol. 20 (11), pp. 3216-3220. Date of Electronic Publication: 2020 Aug 30.
Typ publikacji :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Postoperative Complications*
COVID-19/*epidemiology
Kidney Transplantation/*adverse effects
Meningoencephalitis/*epidemiology
Pancreas Transplantation/*adverse effects
RNA, Viral/*genetics
SARS-CoV-2/*genetics
Aged ; Comorbidity ; Humans ; Male ; Meningoencephalitis/diagnosis ; Pandemics ; Transplant Recipients ; Transplantation, Homologous
Raport
Tytuł :
Differential Diagnosis of Interstitial Allograft Rejection and BKV Nephropathy by T-cell Receptor Sequencing.
Autorzy :
Stervbo U; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.
Nienen M; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Immunology, Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin, Germany.
Hecht J; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
Viebahn R; Department of Surgery, Ruhr-University Bochum, Knappschaftskrankenhaus, Bochum, Germany.
Amann K; Department Nephropathology, University Hospital Erlangen, Erlangen, Germany.
Westhoff TH; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.
Babel N; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
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Źródło :
Transplantation [Transplantation] 2020 Apr; Vol. 104 (4), pp. e107-e108.
Typ publikacji :
Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Sequence Analysis, DNA*
BK Virus/*pathogenicity
Graft Rejection/*diagnosis
Kidney Transplantation/*adverse effects
Opportunistic Infections/*diagnosis
Polyomavirus Infections/*diagnosis
Tumor Virus Infections/*diagnosis
BK Virus/immunology ; Diagnosis, Differential ; Graft Rejection/genetics ; Graft Rejection/immunology ; Graft Rejection/prevention & control ; High-Throughput Nucleotide Sequencing ; Humans ; Immunocompromised Host ; Immunosuppressive Agents/adverse effects ; Male ; Opportunistic Infections/genetics ; Opportunistic Infections/immunology ; Opportunistic Infections/virology ; Polyomavirus Infections/genetics ; Polyomavirus Infections/immunology ; Polyomavirus Infections/virology ; Predictive Value of Tests ; Treatment Outcome ; Tumor Virus Infections/genetics ; Tumor Virus Infections/immunology ; Tumor Virus Infections/virology ; Viral Load ; Young Adult
Raport
Tytuł :
Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial.
Autorzy :
Roemhild A; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Otto NM; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Moll G; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.
Abou-El-Enein M; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Kaiser D; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Bold G; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Schachtner T; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Choi M; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Oellinger R; Department of Abdominal and Transplant Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Landwehr-Kenzel S; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Juerchott K; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Medical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Sawitzki B; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Medical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Giesler C; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Sefrin A; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Beier C; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Wagner DL; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Schlickeiser S; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Medical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Streitz M; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Medical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Schmueck-Henneresse M; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Amini L; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.
Stervbo U; Medical Department 1, University hospitals of the Ruhr University of Bochum, Herne, Germany.
Babel N; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Medical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.; Medical Department 1, University hospitals of the Ruhr University of Bochum, Herne, Germany.
Volk HD; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.; Institute of Medical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Reinke P; Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany .; Berlin Centre for Advanced Therapies (BeCAT), Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, D-13353 Berlin, Germany.; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
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Źródło :
BMJ (Clinical research ed.) [BMJ] 2020 Oct 21; Vol. 371, pp. m3734. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
MeSH Terms :
Immunosuppression/*methods
Immunosuppressive Agents/*administration & dosage
Kidney Transplantation/*methods
T-Lymphocytes, Regulatory/*transplantation
Tacrolimus/*administration & dosage
Adult ; Allografts/immunology ; Feasibility Studies ; Female ; Germany ; Graft Survival/immunology ; Humans ; Infusions, Intravenous ; Kidney/immunology ; Living Donors ; Male ; Middle Aged ; Postoperative Period ; Treatment Outcome ; Withholding Treatment
Czasopismo naukowe

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