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Tytuł :
Design and Synthesis of Pyrano[3,2- b ]indolones Showing Antimycobacterial Activity.
Autorzy :
Monakhova N; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russian Federation.
Korduláková J
Vocat A; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
Egorova A; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russian Federation.
Lepioshkin A; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russian Federation.
Salina EG; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russian Federation.
Nosek J
Repková E
Zemanová J
Jurdáková H
Górová R
Roh J; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové 50005, Czech Republic.
Degiacomi G; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Pavia 27100, Italy.
Sammartino JC; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Pavia 27100, Italy.
Pasca MR; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Pavia 27100, Italy.
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
Mikušová K
Makarov V; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russian Federation.
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Źródło :
ACS infectious diseases [ACS Infect Dis] 2021 Jan 08; Vol. 7 (1), pp. 88-100. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Latent Tuberculosis*
Mycobacterium tuberculosis*/genetics
Tuberculosis*
Antitubercular Agents/pharmacology ; Humans
Czasopismo naukowe
Tytuł :
6,11-Dioxobenzo[ f ]pyrido[1,2- a ]indoles Kill Mycobacterium tuberculosis by Targeting Iron-Sulfur Protein Rv0338c (IspQ), A Putative Redox Sensor.
Autorzy :
Székely R; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Rengifo-Gonzalez M; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Singh V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town, Anzio Road, Observatory 7925, Cape Town 7701, South Africa.
Riabova O; FRC Fundamentals of Biotechnology, Russian Academy of Science, 119071 Moscow, Russian Federation.
Benjak A; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Piton J; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Cimino M; Microbial Individuality and Infection, Institut Pasteur, 75015 Paris, France.
Kornobis E; Biomics, C2RT, Institut Pasteur, 75015 Paris, France.; Hub Bioinformatique et Biostatistique, USR 3756 CNRS, Institut Pasteur, 75015 Paris, France.
Mizrahi V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town, Anzio Road, Observatory 7925, Cape Town 7701, South Africa.
Johnsson K; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Manina G; Microbial Individuality and Infection, Institut Pasteur, 75015 Paris, France.
Makarov V; FRC Fundamentals of Biotechnology, Russian Academy of Science, 119071 Moscow, Russian Federation.
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.; Microbial Individuality and Infection, Institut Pasteur, 75015 Paris, France.
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Źródło :
ACS infectious diseases [ACS Infect Dis] 2020 Nov 13; Vol. 6 (11), pp. 3015-3025. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Iron-Sulfur Proteins*/genetics
Iron-Sulfur Proteins*/metabolism
Mycobacterium tuberculosis*/genetics
Mycobacterium tuberculosis*/metabolism
Tuberculosis*
Humans ; Indoles ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
Multicenter analysis of sputum microbiota in tuberculosis patients.
Autorzy :
Sala C; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Benjak A; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Goletti D; National Institute for Infectious Diseases 'L. Spallanzani'-IRCCS, Rome, Italy.
Banu S; icddr,b, Dhaka, Bangladesh.
Mazza-Stadler J; Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Jaton K; Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Busso P; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Remm S; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Leleu M; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.; BioInformatics Competence Center, UNIL-EPFL, Lausanne, Switzerland.
Rougemont J; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Department of Theoretical Physics, University of Geneva, Geneva, Switzerland.
Palmieri F; National Institute for Infectious Diseases 'L. Spallanzani'-IRCCS, Rome, Italy.
Cuzzi G; National Institute for Infectious Diseases 'L. Spallanzani'-IRCCS, Rome, Italy.
Butera O; National Institute for Infectious Diseases 'L. Spallanzani'-IRCCS, Rome, Italy.
Vanini V; National Institute for Infectious Diseases 'L. Spallanzani'-IRCCS, Rome, Italy.
Kabir S; icddr,b, Dhaka, Bangladesh.
Rahman SMM; icddr,b, Dhaka, Bangladesh.
Nicod L; Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Cole ST; Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
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Źródło :
PloS one [PLoS One] 2020 Oct 12; Vol. 15 (10), pp. e0240250. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Sputum/*microbiology
Tuberculosis/*microbiology
Adult ; Aged ; Bangladesh ; Biomarkers/blood ; DNA, Ribosomal ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Italy ; Male ; Middle Aged ; RNA, Ribosomal, 16S ; Switzerland ; Tuberculosis/blood ; Young Adult
Czasopismo naukowe
Tytuł :
Structural and DNA binding properties of mycobacterial integration host factor mIHF.
Autorzy :
Odermatt NT; École Polytechnique Fédérale de Lausanne, School of Life Sciences, Station 19, 1015 Lausanne, Switzerland. Electronic address: .
Lelli M; Department of Chemistry, University of Florence, Via della Lastruccia, 3-13, 50019 Sesto Fiorentino, FI, Italy. Electronic address: .
Herrmann T; University of Lyon, Institute for Analytical Sciences - Center for High Field NMR, CNRS UMR 5280, ENS Lyon, UCB Lyon 1, France. Electronic address: .
Abriata LA; École Polytechnique Fédérale de Lausanne, School of Life Sciences, Station 19, 1015 Lausanne, Switzerland. Electronic address: .
Japaridze A; École Polytechnique Fédérale de Lausanne, School of Basic Sciences, Route de la Sorge, 1015 Lausanne, Switzerland. Electronic address: .
Voilquin H; École Polytechnique Fédérale de Lausanne, School of Basic Sciences, Route de la Sorge, 1015 Lausanne, Switzerland.
Singh R; École Polytechnique Fédérale de Lausanne, School of Life Sciences, Station 19, 1015 Lausanne, Switzerland.
Piton J; École Polytechnique Fédérale de Lausanne, School of Life Sciences, Station 19, 1015 Lausanne, Switzerland.
Emsley L; École Polytechnique Fédérale de Lausanne, School of Basic Sciences, Av. F.-A. Forel 2, 1015 Lausanne, Switzerland. Electronic address: .
Dietler G; École Polytechnique Fédérale de Lausanne, School of Basic Sciences, Route de la Sorge, 1015 Lausanne, Switzerland. Electronic address: .
Cole ST; École Polytechnique Fédérale de Lausanne, School of Life Sciences, Station 19, 1015 Lausanne, Switzerland. Electronic address: stewart..
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Źródło :
Journal of structural biology [J Struct Biol] 2020 Mar 01; Vol. 209 (3), pp. 107434. Date of Electronic Publication: 2019 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*ultrastructure
Integration Host Factors/*ultrastructure
Mycobacterium tuberculosis/*genetics
Tuberculosis/*microbiology
Binding Sites/genetics ; DNA, Bacterial/genetics ; DNA-Binding Proteins/genetics ; Host-Pathogen Interactions/genetics ; Humans ; Integration Host Factors/genetics ; Magnetic Resonance Spectroscopy ; Microscopy, Atomic Force ; Mycobacterium tuberculosis/pathogenicity ; Protein Conformation, alpha-Helical/genetics ; Streptomyces coelicolor/genetics ; Tuberculosis/genetics
Czasopismo naukowe
Tytuł :
Polarly Localized EccE 1 Is Required for ESX-1 Function and Stabilization of ESX-1 Membrane Proteins in Mycobacterium tuberculosis.
Autorzy :
Soler-Arnedo P; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Sala C; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Zhang M; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Cole ST; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland stewart..
Piton J; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland stewart..
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Źródło :
Journal of bacteriology [J Bacteriol] 2020 Feb 11; Vol. 202 (5). Date of Electronic Publication: 2020 Feb 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Antigens, Bacterial/*genetics
Antigens, Bacterial/*metabolism
Bacterial Proteins/*genetics
Bacterial Proteins/*metabolism
Mycobacterium tuberculosis/*physiology
Tuberculosis/*microbiology
Gene-Environment Interaction ; Genome, Bacterial ; Host-Pathogen Interactions ; Humans ; Membrane Proteins ; Metals/metabolism ; Mutation ; Protein Stability ; Protein Transport ; Proteomics ; Stress, Physiological ; Virulence
Czasopismo naukowe
Tytuł :
Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169).
Autorzy :
Lupien A; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Vocat A; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Foo CS; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Blattes E; Innovative Medicines for Tuberculosis (iM4TB), Lausanne, Switzerland.
Gillon JY; Innovative Medicines for Tuberculosis (iM4TB), Lausanne, Switzerland.
Makarov V; Department of Stresses of Microorganisms, A. N. Bach Institute of Biochemistry, Moscow, Russian Federation.
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland stewart..
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2018 Oct 24; Vol. 62 (11). Date of Electronic Publication: 2018 Oct 24 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antitubercular Agents/*pharmacology
Benzothiazoles/*pharmacology
Piperazines/*pharmacology
Thiazines/*pharmacology
Tuberculosis/*drug therapy
Animals ; Cell Line, Tumor ; Clofazimine/pharmacology ; Clomiphene/pharmacology ; Diarylquinolines/pharmacology ; Drug Resistance, Multiple, Bacterial/drug effects ; Ethambutol/pharmacology ; Hep G2 Cells ; Humans ; Isoniazid/pharmacology ; Mice ; Mice, Inbred BALB C ; Microbial Sensitivity Tests/methods ; Mycobacterium tuberculosis/drug effects ; Oxazolidinones/pharmacology ; Pyrazinamide/pharmacology ; Rifampin/pharmacology ; Tuberculosis, Multidrug-Resistant/drug therapy
Czasopismo naukowe
Tytuł :
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis.
Autorzy :
Foo CS; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Lupien A; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Kienle M; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.
Vocat A; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Benjak A; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Sommer R; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Lamprecht DA; Africa Health Research Institute, Durban, South Africa.
Steyn AJC; Africa Health Research Institute, Durban, South Africa.; Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Pethe K; Lee Kong Chian School of Medicine and School of Biological Sciences, Nanyang Technological University, Singapore.
Piton J; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Altmann KH; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.
Cole ST; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland stewart..
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Źródło :
MBio [mBio] 2018 Oct 09; Vol. 9 (5). Date of Electronic Publication: 2018 Oct 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antitubercular Agents/*pharmacology
Bacterial Proteins/*antagonists & inhibitors
Mycobacterium tuberculosis/*drug effects
Piperazines/*pharmacology
Tuberculosis/*drug therapy
Amides/pharmacology ; Amides/therapeutic use ; Animals ; Cell Line ; Electron Transport Complex III/metabolism ; Female ; Humans ; Macrophages/drug effects ; Macrophages/microbiology ; Mice ; Mice, Inbred BALB C ; Microbial Sensitivity Tests ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł :
Small contribution of gold mines to the ongoing tuberculosis epidemic in South Africa: a modeling-based study.
Autorzy :
Chang ST; Institute for Disease Modeling, Bellevue, Washington, USA. .
Chihota VN; Aurum Institute, Johannesburg, South Africa.; School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.; Foundation for Innovative New Diagnostics, Geneva, Switzerland.
Fielding KL; School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Grant AD; School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.; Africa Health Research Institute, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Houben RM; TB Modelling Group, CMMID, TB Centre, London School of Hygiene and Tropical Medicine, London, UK.
White RG; TB Modelling Group, CMMID, TB Centre, London School of Hygiene and Tropical Medicine, London, UK.
Churchyard GJ; Aurum Institute, Johannesburg, South Africa.; School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.; Advancing Treatment and Care for TB/HIV, South African Medical Research Council, Johannesburg, South Africa.
Eckhoff PA; Institute for Disease Modeling, Bellevue, Washington, USA.
Wagner BG; Institute for Disease Modeling, Bellevue, Washington, USA.
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Źródło :
BMC medicine [BMC Med] 2018 Apr 12; Vol. 16 (1), pp. 52. Date of Electronic Publication: 2018 Apr 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mining/*methods
Mycobacterium tuberculosis/*pathogenicity
Tuberculosis/*epidemiology
Adult ; Epidemics ; Female ; Gold ; Humans ; Incidence ; Male ; South Africa
Czasopismo naukowe
Tytuł :
Tuberculosis drug discovery needs public-private consortia.
Autorzy :
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Station 19, 1015 Lausanne, Switzerland. Electronic address: stewart..
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Źródło :
Drug discovery today [Drug Discov Today] 2017 Mar; Vol. 22 (3), pp. 477-478. Date of Electronic Publication: 2016 Oct 04.
Typ publikacji :
Editorial
MeSH Terms :
Drug Discovery/*organization & administration
Public-Private Sector Partnerships/*organization & administration
Tuberculosis/*drug therapy
Humans
Opinia redakcyjna
Tytuł :
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.
Autorzy :
Singh V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town , Anzio Road, Observatory 7925, South Africa.
Donini S; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale , Via Bovio 6, 28100 Novara, Italy.
Pacitto A; Department of Biochemistry, University of Cambridge , 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.
Sala C; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Hartkoorn RC; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Dhar N; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Keri G; Vichem Chemie , Herman Ottó út 15, Budapest, 1022 Hungary.
Ascher DB; Department of Biochemistry, University of Cambridge , 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.
Mondésert G; Sanofi-Aventis Research & Development , Infectious Diseases Unit, Biology Group, Campus Mérieux, 1541 avenue Marcel Mérieux, 69280 Marcy L'Etoile, France.
Vocat A; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Lupien A; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Sommer R; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Vermet H; Sanofi-Aventis Research & Development , Infectious Diseases Unit, Biology Group, Campus Mérieux, 1541 avenue Marcel Mérieux, 69280 Marcy L'Etoile, France.
Lagrange S; Sanofi-Aventis Research & Development , Infectious Diseases Unit, Biology Group, Campus Mérieux, 1541 avenue Marcel Mérieux, 69280 Marcy L'Etoile, France.
Buechler J; Alere (San Diego) , Summer Ridge Road, San Diego, California 92121, United States.
Warner DF; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town , Anzio Road, Observatory 7925, South Africa.
McKinney JD; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Pato J; Vichem Chemie , Herman Ottó út 15, Budapest, 1022 Hungary.
Cole ST; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
Blundell TL; Department of Biochemistry, University of Cambridge , 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.
Rizzi M; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale , Via Bovio 6, 28100 Novara, Italy.
Mizrahi V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town , Anzio Road, Observatory 7925, South Africa.
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Źródło :
ACS infectious diseases [ACS Infect Dis] 2017 Jan 13; Vol. 3 (1), pp. 5-17. Date of Electronic Publication: 2016 Sep 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antitubercular Agents/*pharmacology
IMP Dehydrogenase/*antagonists & inhibitors
Mycobacterium/*drug effects
Sulfones/*pharmacology
Tuberculosis/*drug therapy
Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Drug Discovery ; Drug Resistance, Bacterial ; Gene Expression Regulation, Bacterial/drug effects ; Gene Expression Regulation, Enzymologic/drug effects ; Genome, Bacterial ; IMP Dehydrogenase/genetics ; IMP Dehydrogenase/metabolism ; Mice ; Mice, Inbred C57BL ; Mutation ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł :
Inhibiting Mycobacterium tuberculosis within and without.
Autorzy :
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Station 19, 1015 Lausanne, Switzerland stewart..
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Źródło :
Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2016 Nov 05; Vol. 371 (1707).
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Discovery*
Antitubercular Agents/*pharmacology
Mycobacterium tuberculosis/*drug effects
Tuberculosis/*drug therapy
Antitubercular Agents/analysis ; Humans ; Mycobacterium tuberculosis/physiology
Czasopismo naukowe
Tytuł :
Cost-effectiveness and resource implications of aggressive action on tuberculosis in China, India, and South Africa: a combined analysis of nine models.
Autorzy :
Menzies NA; Department of Global Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA; Center for Health Decision Science, Harvard T H Chan School of Public Health, Boston, MA, USA. Electronic address: .
Gomez GB; Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands; Department of Global Health, Academic Medical Center, University of Amsterdam, Netherlands; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
Bozzani F; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
Chatterjee S; Public Health Foundation of India, Delhi NCR, India.
Foster N; Health Economics Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Baena IG; Monitoring and Evaluation Unit, Geneva, Switzerland.
Laurence YV; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
Qiang S; School of Health Care Management and Key Laboratory of Health Economics and Policy Research of Ministry of Health, Shandong University, Jinan, China.
Siroka A; Global TB Programme, Geneva, Switzerland.
Sweeney S; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
Verguet S; Department of Global Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA.
Arinaminpathy N; Public Health Foundation of India, Delhi NCR, India; Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Azman AS; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Bendavid E; Department of Medicine, Stanford University, Stanford, CA, USA.
Chang ST; Institute for Disease Modeling, Seattle, WA, USA.
Cohen T; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Denholm JT; Victorian Tuberculosis Program at the Peter Doherty Institute, Melbourne, VIC, Australia; Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, Australia.
Dowdy DW; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Eckhoff PA; Institute for Disease Modeling, Seattle, WA, USA.
Goldhaber-Fiebert JD; Stanford Health Policy, Centers for Health Policy and Primary Care and Outcomes Research, Stanford University, Stanford, CA, USA.
Handel A; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Huynh GH; Institute for Disease Modeling, Seattle, WA, USA; Synthetic Neurobiology Group, Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
Lalli M; TB Modelling Group, TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London, UK.
Lin HH; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Mandal S; Public Health Foundation of India, Delhi NCR, India.
McBryde ES; Victorian Tuberculosis Program at the Peter Doherty Institute, Melbourne, VIC, Australia; Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, Australia; Burnet Institute, Melbourne, VIC, Australia.
Pandey S; Public Health Foundation of India, Delhi NCR, India.
Salomon JA; Department of Global Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA; Center for Health Decision Science, Harvard T H Chan School of Public Health, Boston, MA, USA.
Suen SC; Department of Management Science and Engineering, Stanford University, Stanford, CA, USA.
Sumner T; TB Modelling Group, TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London, UK.
Trauer JM; Victorian Tuberculosis Program at the Peter Doherty Institute, Melbourne, VIC, Australia; Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, Australia; Burnet Institute, Melbourne, VIC, Australia.
Wagner BG; Institute for Disease Modeling, Seattle, WA, USA.
Whalen CC; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Wu CY; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Boccia D; Faculty of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London, UK.
Chadha VK; Epidemiology and Research Division, National Tuberculosis Institute, Bangalore, India.
Charalambous S; Aurum Institute, Johannesburg, South Africa.
Chin DP; Bill & Melinda Gates Foundation, Seattle, WA, USA.
Churchyard G; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; Aurum Institute, Johannesburg, South Africa; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.
Daniels C; Stop TB Partnership, Geneva, Switzerland.
Dewan P; Bill & Melinda Gates Foundation, New Delhi, India.
Ditiu L; Stop TB Partnership, Geneva, Switzerland.
Eaton JW; Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Grant AD; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; School of Public Health, University of Witwatersrand, Johannesburg, South Africa; Africa Centre for Population Health, School of Nursing & Public Health, University of KwaZulu-Natal, Durban, South Africa.
Hippner P; Aurum Institute, Johannesburg, South Africa.
Hosseini M; Strategic Information Department, The Global Fund, Geneva, Switzerland.
Mametja D; National Department of Health, Pretoria, South Africa.
Pretorius C; Avenir Health, Glastonbury, CT, USA.
Pillay Y; National Department of Health, Pretoria, South Africa.
Rade K; World Health Organization Country Office for India, New Delhi, India.
Sahu S; Stop TB Partnership, Geneva, Switzerland.
Wang L; National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Houben RMGJ; TB Modelling Group, TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London, UK.
Kimerling ME; KNCV Tuberculosis Foundation, The Hague, Netherlands.
White RG; TB Modelling Group, TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London, UK.
Vassall A; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
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Źródło :
The Lancet. Global health [Lancet Glob Health] 2016 Nov; Vol. 4 (11), pp. e816-e826. Date of Electronic Publication: 2016 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Cost-Benefit Analysis*
Delivery of Health Care*/economics
Health Care Costs*
Health Resources*
Health Services Needs and Demand*
Quality-Adjusted Life Years*
Tuberculosis/*prevention & control
China ; Forecasting ; Goals ; Health Expenditures ; Health Policy ; Health Services Accessibility ; Humans ; India ; Models, Theoretical ; Patient Acceptance of Health Care ; South Africa ; Tuberculosis/economics ; Tuberculosis/mortality
Czasopismo naukowe
Tytuł :
Feasibility of achieving the 2025 WHO global tuberculosis targets in South Africa, China, and India: a combined analysis of 11 mathematical models.
Autorzy :
Houben RMGJ; TB Modelling Group, TB Centre, London School of Hygiene and Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: .
Menzies NA; Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.
Sumner T; TB Modelling Group, TB Centre, London School of Hygiene and Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.
Huynh GH; Institute for Disease Modeling, Seattle, WA, USA.
Arinaminpathy N; Department of Infectious Disease Epidemiology, Imperial College London, London, UK; Public Health Foundation of India, Delhi NCR, India.
Goldhaber-Fiebert JD; Stanford Health Policy, Centers for Health Policy and Primary Care and Outcomes Research, Stanford University, Stanford, CA, USA.
Lin HH; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Wu CY; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Mandal S; Public Health Foundation of India, Delhi NCR, India.
Pandey S; Public Health Foundation of India, Delhi NCR, India.
Suen SC; Management Science and Engineering Dept, Stanford University, Stanford, CA, USA.
Bendavid E; Department of Medicine, Stanford University, Stanford, CA, USA.
Azman AS; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Dowdy DW; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Bacaër N; IRD, UMMISCO, Bondy, France.
Rhines AS; Department of Biology, Stanford University, Stanford, CA, USA; Johnson & Johnson Global Public Health, Raritan, NJ, USA.
Feldman MW; Department of Biology, Stanford University, Stanford, CA, USA.
Handel A; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Whalen CC; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Chang ST; Institute for Disease Modeling, Seattle, WA, USA.
Wagner BG; Institute for Disease Modeling, Seattle, WA, USA.
Eckhoff PA; Institute for Disease Modeling, Seattle, WA, USA.
Trauer JM; The Burnet Institute, Melbourne, Australia; The Victorian Infectious Diseases Service, at the Peter Doherty Institute, Melbourne, Australia; Department of Microbiology and Immunology, the University of Melbourne at the Peter Doherty Institute, Melbourne, Australia.
Denholm JT; The Victorian Infectious Diseases Service, at the Peter Doherty Institute, Melbourne, Australia; Department of Microbiology and Immunology, the University of Melbourne at the Peter Doherty Institute, Melbourne, Australia.
McBryde ES; The Burnet Institute, Melbourne, Australia; The Victorian Infectious Diseases Service, at the Peter Doherty Institute, Melbourne, Australia; Department of Microbiology and Immunology, the University of Melbourne at the Peter Doherty Institute, Melbourne, Australia.
Cohen T; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Salomon JA; Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.
Pretorius C; Avenir Health, Glastonbury, CT, USA.
Lalli M; TB Modelling Group, TB Centre, London School of Hygiene and Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.
Eaton JW; Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Boccia D; Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.
Hosseini M; Strategic Information Department, The Global Fund, Geneva, Switzerland.
Gomez GB; Department of Global Health, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Global Health and Development, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Sahu S; Stop TB Partnership, Geneva, Switzerland.
Daniels C; Stop TB Partnership, Geneva, Switzerland.
Ditiu L; Stop TB Partnership, Geneva, Switzerland.
Chin DP; Bill and Melinda Gates Foundation, China Office, Beijing, China.
Wang L; National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Chadha VK; Epidemiology and Research Division, National Tuberculosis Institute, Bangalore, India.
Rade K; World Health Organization, Country Office for India, New Delhi, India.
Dewan P; The Bill & Melinda Gates Foundation, New Delhi, India.
Hippner P; Aurum Institute. Johannesburg, South Africa.
Charalambous S; Aurum Institute. Johannesburg, South Africa.
Grant AD; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.
Churchyard G; Aurum Institute. Johannesburg, South Africa; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.
Pillay Y; National Department of Health, Pretoria, South Africa.
Mametja LD; National Department of Health, Pretoria, South Africa.
Kimerling ME; Bill and Melinda Gates foundation, Seattle, WA, USA (currently KNCV Tuberculosisn Foundation, The Hague, Netherlands).
Vassall A; Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
White RG; TB Modelling Group, TB Centre, London School of Hygiene and Tropical Medicine, London, UK; Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK.
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Źródło :
The Lancet. Global health [Lancet Glob Health] 2016 Nov; Vol. 4 (11), pp. e806-e815. Date of Electronic Publication: 2016 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Achievement*
Delivery of Health Care*
Goals*
Tuberculosis/*prevention & control
Antitubercular Agents/therapeutic use ; Cause of Death ; China ; Forecasting ; HIV Infections/complications ; Health Services Accessibility ; Humans ; Incidence ; India ; Isoniazid/therapeutic use ; Mass Screening ; Models, Theoretical ; South Africa ; Tuberculosis/epidemiology ; Tuberculosis/therapy ; Tuberculosis/transmission ; World Health Organization
Czasopismo naukowe
Tytuł :
DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization.
Autorzy :
Brecik M; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Centárová I; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Mukherjee R; ‡Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Kolly GS; ‡Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Huszár S; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Bobovská A; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Kilacsková E; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Mokošová V; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Svetlíková Z; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Šarkan M; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Neres J; ‡Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Korduláková J; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
Cole ST; ‡Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Mikušová K; †Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.
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Źródło :
ACS chemical biology [ACS Chem Biol] 2015 Jul 17; Vol. 10 (7), pp. 1631-6. Date of Electronic Publication: 2015 Apr 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alcohol Oxidoreductases/*analysis
Alcohol Oxidoreductases/*metabolism
Antitubercular Agents/*pharmacology
Bacterial Proteins/*analysis
Bacterial Proteins/*metabolism
Cell Wall/*metabolism
Mycobacterium tuberculosis/*cytology
Mycobacterium tuberculosis/*enzymology
Tuberculosis/*microbiology
Cell Wall/drug effects ; Humans ; Mycobacterium tuberculosis/drug effects ; Tuberculosis/drug therapy
Czasopismo naukowe
Tytuł :
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.
Autorzy :
Wassermann R; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Gulen MF; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Sala C; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Perin SG; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Lou Y; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Rybniker J; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; First Department of Internal Medicine, University of Cologne, 50937 Cologne, Germany.
Schmid-Burgk JL; Institute for Molecular Medicine, University Hospital, University of Bonn, 53127 Bonn, Germany.
Schmidt T; Institute for Molecular Medicine, University Hospital, University of Bonn, 53127 Bonn, Germany.
Hornung V; Institute for Molecular Medicine, University Hospital, University of Bonn, 53127 Bonn, Germany.
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address: stewart..
Ablasser A; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2015 Jun 10; Vol. 17 (6), pp. 799-810. Date of Electronic Publication: 2015 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
DNA, Bacterial/*metabolism
Host-Pathogen Interactions/*immunology
Interferon Type I/*metabolism
Mycobacterium tuberculosis/*genetics
Nucleotidyltransferases/*metabolism
Tuberculosis/*microbiology
Animals ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł :
The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo.
Autorzy :
Boldrin F; Department of Molecular Medicine, University of Padua, Padua, Italy.
Ventura M; Department of Molecular Medicine, University of Padua, Padua, Italy.
Degiacomi G; Department of Molecular Medicine, University of Padua, Padua, Italy.
Ravishankar S; AstraZeneca India Pvt. Ltd., Bangalore, India.
Sala C; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Svetlikova Z; Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Ambady A; AstraZeneca India Pvt. Ltd., Bangalore, India.
Dhar N; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Kordulakova J; Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Zhang M; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Serafini A; Department of Molecular Medicine, University of Padua, Padua, Italy.
Vishwas KG; AstraZeneca India Pvt. Ltd., Bangalore, India.
Kolly GS; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Kumar N; AstraZeneca India Pvt. Ltd., Bangalore, India.
Palù G; Department of Molecular Medicine, University of Padua, Padua, Italy.
Guerin ME; Unidad de Biofísica, Centro Mixto Consejo Superior de Investigaciones Científicas-Universidad del País Vasco/Euskal Herriko Unibertsitatea, Bizkaia, Spain Departamento de Bioquímica, Universidad del País Vasco, Bizkaia, Spain IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
Mikusova K; Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Cole ST; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Manganelli R; Department of Molecular Medicine, University of Padua, Padua, Italy .
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Źródło :
Journal of bacteriology [J Bacteriol] 2014 Oct; Vol. 196 (19), pp. 3441-51. Date of Electronic Publication: 2014 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*metabolism
Mannosyltransferases/*metabolism
Mycobacterium tuberculosis/*enzymology
Mycobacterium tuberculosis/*growth & development
Tuberculosis/*microbiology
Animals ; Bacterial Proteins/genetics ; Female ; Humans ; Macrophages/metabolism ; Macrophages/microbiology ; Mannosyltransferases/genetics ; Mice ; Mice, Inbred C57BL ; Mycobacterium tuberculosis/genetics ; Phosphatidylinositols/biosynthesis
Czasopismo naukowe
Tytuł :
Tuberculosis drug discovery in the post-post-genomic era.
Autorzy :
Lechartier B; Ecole Polytechnique Fédérale de Lausanne Global Health Institute, Lausanne, Switzerland.
Rybniker J
Zumla A
Cole ST
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Źródło :
EMBO molecular medicine [EMBO Mol Med] 2014 Feb; Vol. 6 (2), pp. 158-68. Date of Electronic Publication: 2014 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Discovery*
Genomics*
Antitubercular Agents/*therapeutic use
Tuberculosis/*drug therapy
Animals ; Antitubercular Agents/pharmacology ; Global Health ; Host-Pathogen Interactions/drug effects ; Humans ; Tuberculosis/diagnosis
Czasopismo naukowe
Tytuł :
Advances in the development of new tuberculosis drugs and treatment regimens.
Autorzy :
Zumla A; Center for Clinical Microbiology, Division of Infection and Immunity, University College London Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK.
Nahid P
Cole ST
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Źródło :
Nature reviews. Drug discovery [Nat Rev Drug Discov] 2013 May; Vol. 12 (5), pp. 388-404.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
Antitubercular Agents/*therapeutic use
Tuberculosis/*drug therapy
Anti-Bacterial Agents/therapeutic use ; Biomarkers ; Clinical Trials as Topic ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Drug Combinations ; Drug Discovery/trends ; Drug Evaluation, Preclinical/trends ; Drug Resistance, Multiple, Bacterial ; Humans ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/genetics ; Research Design
Czasopismo naukowe
Tytuł :
Database resources for the tuberculosis community.
Autorzy :
Lew JM; Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland.
Mao C
Shukla M
Warren A
Will R
Kuznetsov D
Xenarios I
Robertson BD
Gordon SV
Schnappinger D
Cole ST
Sobral B
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Źródło :
Tuberculosis (Edinburgh, Scotland) [Tuberculosis (Edinb)] 2013 Jan; Vol. 93 (1), pp. 12-7. Date of Electronic Publication: 2013 Jan 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Databases, Genetic*
Mycobacterium tuberculosis/*genetics
Tuberculosis/*microbiology
Genome, Bacterial ; Genomics ; Humans ; Internet
Czasopismo naukowe

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