Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Stimulator"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 4598
Tytuł:
Deep Flow Cytometry Unveils Distinct Immune Cell Subsets in Inducible T Cell Co-Stimulator Ligand (ICOSL)- and ICOS-Knockout Mice during Experimental Autoimmune Encephalomyelitis.
Autorzy:
Raineri D; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Abreu H; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Vilardo B; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Kustrimovic N; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Venegoni C; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Cappellano G; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Chiocchetti A; Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, University of Eastern Piedmont, 28100 Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, University of Eastern Piedmont, 28100 Novara, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Encephalomyelitis, Autoimmune, Experimental*/metabolism
Mice ; Animals ; Mice, Knockout ; Flow Cytometry ; Inducible T-Cell Co-Stimulator Ligand/genetics ; Ligands ; Mice, Inbred C57BL ; T-Lymphocytes ; Inducible T-Cell Co-Stimulator Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy.
Autorzy:
Saffarzadeh N; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 141 52, Huddinge, Stockholm, Sweden.
Foord E; Circio AB, Stockholm, Sweden.
O'Leary E; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 141 52, Huddinge, Stockholm, Sweden.; Circio AB, Stockholm, Sweden.
Mahmoun R; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 141 52, Huddinge, Stockholm, Sweden.
Birkballe Hansen T; Circio AB, Stockholm, Sweden.
Levitsky V; Circio AB, Stockholm, Sweden.
Poiret T; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 141 52, Huddinge, Stockholm, Sweden. .
Uhlin M; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 141 52, Huddinge, Stockholm, Sweden.; Department of Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
Pokaż więcej
Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 07; Vol. 22 (1), pp. 250. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Oncolytic Viruses*
Neoplasms*/therapy
Oncolytic Virotherapy*
Humans ; Adenoviridae ; CD8-Positive T-Lymphocytes ; CD4-Positive T-Lymphocytes ; Inducible T-Cell Co-Stimulator Protein ; Antibodies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice.
Autorzy:
Sankaranarayanan I; Pain Neurobiology Research Group, University of Texas at Dallas, 800 W Campbell Rd, Richardson, TX, 75080, USA.
Tavares-Ferreira D; Pain Neurobiology Research Group, University of Texas at Dallas, 800 W Campbell Rd, Richardson, TX, 75080, USA.
Mwirigi JM; Pain Neurobiology Research Group, University of Texas at Dallas, 800 W Campbell Rd, Richardson, TX, 75080, USA.
Mejia GL; Pain Neurobiology Research Group, University of Texas at Dallas, 800 W Campbell Rd, Richardson, TX, 75080, USA.
Burton MD; Neuroimmunology and Behavior Laboratory, Department of Neuroscience, Center for Advanced Pain Studies, School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX, USA.
Price TJ; Pain Neurobiology Research Group, University of Texas at Dallas, 800 W Campbell Rd, Richardson, TX, 75080, USA. .
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Feb 11; Vol. 20 (1), pp. 32. Date of Electronic Publication: 2023 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperalgesia*/chemically induced
Hyperalgesia*/drug therapy
Hyperalgesia*/metabolism
Inducible T-Cell Co-Stimulator Protein*/metabolism
Interleukin-10*/metabolism
Neuralgia*/chemically induced
Neuralgia*/drug therapy
Neuralgia*/metabolism
Animals ; Female ; Humans ; Mice ; Antineoplastic Agents/pharmacology ; Ganglia, Spinal/metabolism ; Paclitaxel/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Expression of ICOS in the salivary glands of patients with primary Sjogren's syndrome and its molecular mechanism.
Autorzy:
Li P; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Jin Y; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Zhao R; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Xue Z; Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Ji J; Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Pokaż więcej
Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Nov; Vol. 26 (5). Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Inducible T-Cell Co-Stimulator Protein*/genetics
Inducible T-Cell Co-Stimulator Protein*/metabolism
Salivary Glands*/metabolism
Sjogren's Syndrome*/metabolism
Aquaporin 5/genetics ; Aquaporin 5/metabolism ; Humans ; Saliva/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular and clinical characterization of ICOS expression in breast cancer through large-scale transcriptome data.
Autorzy:
Wang P; Thyroid and Breast Department III, Cangzhou Central Hospital, Cangzhou, Hebei Province, China.
Zhang Q; Thyroid and Breast Department III, Cangzhou Central Hospital, Cangzhou, Hebei Province, China.
Zhang H; Hebei Medical University, Shijiazhuang, Hebei Province, China.
Shao J; Thyroid and Breast Department III, Cangzhou Central Hospital, Cangzhou, Hebei Province, China.
Zhang H; Thyroid and Breast Department III, Cangzhou Central Hospital, Cangzhou, Hebei Province, China.
Wang Z; Thyroid and Breast Department III, Cangzhou Central Hospital, Cangzhou, Hebei Province, China.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2023 Dec 21; Vol. 18 (12), pp. e0293469. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Transcriptome*
Triple Negative Breast Neoplasms*
Humans ; T-Lymphocytes ; Immunotherapy/methods ; Tumor Microenvironment/genetics ; Inducible T-Cell Co-Stimulator Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Divergent molecular networks program functionally distinct CD8 skin-resident memory T cells.
Autorzy:
Park SL; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Christo SN; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Wells AC; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, USA.
Gandolfo LC; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.; School of Mathematics and Statistics, The University of Melbourne, Melbourne, VIC, Australia.; Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.
Zaid A; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Alexandre YO; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Burn TN; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Schröder J; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Collins N; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, USA.
Han SJ; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, USA.
Guillaume SM; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Evrard M; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Castellucci C; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Davies B; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Osman M; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Obers A; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
McDonald KM; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Wang H; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Mueller SN; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Kannourakis G; Institute of Innovation, Science and Sustainability, Federation University Australia, Ballarat, VIC, Australia.; Fiona Elsey Cancer Research Institute, Ballarat, VIC, Australia.
Berzins SP; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.; Institute of Innovation, Science and Sustainability, Federation University Australia, Ballarat, VIC, Australia.; Fiona Elsey Cancer Research Institute, Ballarat, VIC, Australia.
Mielke LA; Olivia Newton-John Cancer Research Institute, La Trobe University School of Cancer Medicine, Heidelberg, VIC, Australia.
Carbone FR; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Kallies A; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Speed TP; School of Mathematics and Statistics, The University of Melbourne, Melbourne, VIC, Australia.; Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.
Belkaid Y; Metaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, USA.; NIAID Microbiome Program, NIAID, National Institutes of Health, Bethesda, MD, USA.
Mackay LK; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2023 Dec; Vol. 382 (6674), pp. 1073-1079. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*/immunology
Immunologic Memory*
Memory T Cells*/immunology
Skin*/immunology
Humans ; Th17 Cells/immunology ; Inducible T-Cell Co-Stimulator Ligand/metabolism ; Proto-Oncogene Proteins c-maf/metabolism ; Interleukin-7/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ICOSL Stimulation by ICOS-Fc Accelerates Cutaneous Wound Healing In Vivo.
Autorzy:
Stoppa I; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; NOVAICOS srls, 28100 Novara, Italy.
Gigliotti CL; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; NOVAICOS srls, 28100 Novara, Italy.
Clemente N; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.
Pantham D; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; NOVAICOS srls, 28100 Novara, Italy.
Dianzani C; Department of Scienza e Tecnologia del Farmaco, University of Turin, 10124 Turin, Italy.
Monge C; Department of Scienza e Tecnologia del Farmaco, University of Turin, 10124 Turin, Italy.
Puricelli C; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; Maggiore della Carità University Hospital, 28100 Novara, Italy.
Rolla R; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; Maggiore della Carità University Hospital, 28100 Novara, Italy.
Sutti S; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.
Renò F; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.
Boldorini R; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; Maggiore della Carità University Hospital, 28100 Novara, Italy.
Boggio E; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; NOVAICOS srls, 28100 Novara, Italy.
Dianzani U; Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), Università del Piemonte Orientale, 28100 Novara, Italy.; Maggiore della Carità University Hospital, 28100 Novara, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 01; Vol. 23 (13). Date of Electronic Publication: 2022 Jul 01.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fc Fragments*/immunology
Immunoglobulin Fc Fragments*/pharmacology
Inducible T-Cell Co-Stimulator Ligand*/genetics
Inducible T-Cell Co-Stimulator Ligand*/immunology
Inducible T-Cell Co-Stimulator Ligand*/metabolism
Inducible T-Cell Co-Stimulator Protein*/genetics
Inducible T-Cell Co-Stimulator Protein*/immunology
Wound Healing*/drug effects
Animals ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Recombinant Proteins/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ICOS deficiency hampers the homeostasis, development and function of NK cells.
Autorzy:
Montes-Casado M; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
Ojeda G; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
Aragoneses-Fenoll L; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
López D; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
de Andrés B; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
Gaspar ML; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
Dianzani U; Interdisciplinary Research Center of Autoimmune Diseases (IRCAD) and Department of Health Sciences, University of Piemonte Orientale (UPO), Novara, Italy.
Rojo JM; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain.
Portolés P; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2019 Jul 08; Vol. 14 (7), pp. e0219449. Date of Electronic Publication: 2019 Jul 08 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inducible T-Cell Co-Stimulator Protein/*genetics
Killer Cells, Natural/*metabolism
Animals ; Apoptosis ; CD11b Antigen/metabolism ; Cell Differentiation ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Inducible T-Cell Co-Stimulator Ligand/genetics ; Inducible T-Cell Co-Stimulator Ligand/metabolism ; Inducible T-Cell Co-Stimulator Protein/deficiency ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Interferon-gamma/metabolism ; Interleukin-2/pharmacology ; Killer Cells, Natural/cytology ; Killer Cells, Natural/drug effects ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phosphorylation/drug effects ; Poly I-C/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Tumor Necrosis Factor Receptor Superfamily, Member 7/metabolism ; Vaccinia/immunology ; Vaccinia/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
T Follicular Helper Cells in Tertiary Lymphoid Structure Contribute to Renal Fibrosis by IL-21.
Autorzy:
Luo R; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Chang D; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Zhang N; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Cheng Y; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Ge S; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Xu G; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 08; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Tertiary Lymphoid Structures*
Glomerulonephritis, IGA*
Animals ; Mice ; T Follicular Helper Cells ; Interleukins ; Inducible T-Cell Co-Stimulator Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis.
Autorzy:
Qin X; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Sun W; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Wang C; Department of Surgery, Shandong Rongjun General Hospital, Jinan, Shandong, 250013, People's Republic of China.
Li M; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Zhao X; Department of Obstetrics and Gynaecology, Shandong University, Jinan, Shandong, 250000, People's Republic of China.
Li C; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Zhang H; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China. .
Pokaż więcej
Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2021 Jul 21; Vol. 19 (1), pp. 114. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Adenomyosis/*metabolism
B7 Antigens/*biosynthesis
Inducible T-Cell Co-Stimulator Ligand/*biosynthesis
Mifepristone/*therapeutic use
Programmed Cell Death 1 Ligand 2 Protein/*biosynthesis
V-Set Domain-Containing T-Cell Activation Inhibitor 1/*biosynthesis
Adenomyosis/drug therapy ; Adenomyosis/genetics ; Adult ; B7 Antigens/antagonists & inhibitors ; B7 Antigens/genetics ; Endometrium/drug effects ; Endometrium/metabolism ; Female ; Gene Expression ; Hormone Antagonists/pharmacology ; Hormone Antagonists/therapeutic use ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Inducible T-Cell Co-Stimulator Ligand/antagonists & inhibitors ; Inducible T-Cell Co-Stimulator Ligand/genetics ; Middle Aged ; Mifepristone/pharmacology ; Programmed Cell Death 1 Ligand 2 Protein/antagonists & inhibitors ; Programmed Cell Death 1 Ligand 2 Protein/genetics ; V-Set Domain-Containing T-Cell Activation Inhibitor 1/antagonists & inhibitors ; V-Set Domain-Containing T-Cell Activation Inhibitor 1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
First-in-human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN-101, a dual CD28/ICOS antagonist, in healthy adult subjects.
Autorzy:
Yang J; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Lickliter JD; Nucleus Network, Melbourne, Victoria, Australia.
Hillson JL; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Means GD; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Sanderson RJ; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Carley K; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Tercero A; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Manjarrez KL; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Wiley JR; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Peng SL; Alpine Immune Sciences, Inc., Seattle, Washington, USA.
Pokaż więcej
Źródło:
Clinical and translational science [Clin Transl Sci] 2021 Jul; Vol. 14 (4), pp. 1314-1326. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
CD28 Antigens*/antagonists & inhibitors
CD28 Antigens*/metabolism
Immunosuppressive Agents*/administration & dosage
Immunosuppressive Agents*/adverse effects
Immunosuppressive Agents*/pharmacokinetics
Inducible T-Cell Co-Stimulator Protein*/antagonists & inhibitors
Inducible T-Cell Co-Stimulator Protein*/metabolism
Adolescent ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Administration, Intravenous ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells.
Autorzy:
Hinrichs AC; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Kruize AA; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Lafeber FPJG; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Leavis HL; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
van Roon JAG; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 26; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Sjogren's Syndrome*
Humans ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Interleukins/metabolism ; Leukocytes, Mononuclear ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Receptors, CXCR5/metabolism ; T-Lymphocytes, Helper-Inducer
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Activated neutrophils polarize protumorigenic interleukin-17A-producing T helper subsets through TNF-α-B7-H2-dependent pathway in human gastric cancer.
Autorzy:
Shan ZG; Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Chen J; Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Liu JS; Department of General Surgery, Qijiang Hospital of the First Affiliated Hospital of Chongqing Medical University, Qijiang, Chongqing, China.
Zhang JY; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Wang TT; Chongqing Key Research Laboratory for Drug Metabolism, Department of Pharmacology, Chongqing Medical University, Chongqing, China.
Teng YS; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Mao FY; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Cheng P; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Zou QM; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Zhou WY; Chongqing Key Research Laboratory for Drug Metabolism, Department of Pharmacology, Chongqing Medical University, Chongqing, China.
Peng LS; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.
Zhao YL; Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Zhuang Y; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing, China.; Department of Gastroenterology,  the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Jiangsu, China.
Pokaż więcej
Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Jun; Vol. 11 (6), pp. e484.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neutrophil Activation*
Inducible T-Cell Co-Stimulator Ligand/*metabolism
Interleukin-17/*metabolism
Neutrophils/*immunology
Stomach Neoplasms/*pathology
T-Lymphocytes, Helper-Inducer/*immunology
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Apoptosis ; Cell Proliferation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Inducible T-Cell Co-Stimulator Ligand/genetics ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Prognosis ; Stomach Neoplasms/immunology ; Stomach Neoplasms/metabolism ; Survival Rate ; Tumor Cells, Cultured ; Tumor Necrosis Factor-alpha/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification of novel NFKB1 and ICOS frameshift variants in patients with CVID.
Autorzy:
Liu A; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Liu Q; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Leng S; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Zhang X; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Feng Q; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Peng J; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Feng G; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Pokaż więcej
Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2023 Mar 08; Vol. 211 (1), pp. 68-77.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Common Variable Immunodeficiency*/genetics
Humans ; Inducible T-Cell Co-Stimulator Protein/genetics ; Mutation/genetics ; Phenotype ; NF-kappa B p50 Subunit/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy.
Autorzy:
Zhao X; The First Clinical Medical College of Gansu, University of Chinese Medicine (Gansu Provincial Hospital), 730000, Lanzhou, Gansu, China.; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.; Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Provincial Hospital, 730000, Gansu, China.; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, 730000, Lanzhou, China.
Wang Y; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.; Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Provincial Hospital, 730000, Gansu, China.; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, 730000, Lanzhou, China.; The First Clinical Medical College of Lanzhou University, 204 Donggang West Road, 730000, Lanzhou, Gansu, China.
Jiang X; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.; Graduate School, Ning Xia Medical University, 750004, Yinchuan, Ningxia, China.
Mo B; The First Clinical Medical College of Gansu, University of Chinese Medicine (Gansu Provincial Hospital), 730000, Lanzhou, Gansu, China.; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.
Wang C; Graduate School, Ning Xia Medical University, 750004, Yinchuan, Ningxia, China.
Tang M; The First Clinical Medical College of Gansu, University of Chinese Medicine (Gansu Provincial Hospital), 730000, Lanzhou, Gansu, China.; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.
Rong Y; The First Clinical Medical College of Gansu, University of Chinese Medicine (Gansu Provincial Hospital), 730000, Lanzhou, Gansu, China.; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.
Zhang G; The First Clinical Medical College of Gansu, University of Chinese Medicine (Gansu Provincial Hospital), 730000, Lanzhou, Gansu, China.; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China.
Hu M; Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China. .
Cai H; General Surgery Clinical Medical Center, Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China. .; Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Provincial Hospital, 730000, Gansu, China. .; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, 730000, Lanzhou, China. .; The First Clinical Medical College of Lanzhou University, 204 Donggang West Road, 730000, Lanzhou, Gansu, China. .; Gansu Provincial Hospital, 730000, Lanzhou, Gansu, China. .
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2023 Feb 28; Vol. 23 (1), pp. 194. Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Immunotherapy*
Neoplasms*/genetics
Neoplasms*/therapy
Humans ; Immunosuppression Therapy ; Liver ; Antigen-Presenting Cells ; Breast ; DNA Modification Methylases ; Inducible T-Cell Co-Stimulator Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differential Modulation of Human M1 and M2 Macrophage Activity by ICOS-Mediated ICOSL Triggering.
Autorzy:
Gigliotti CL; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.; NOVAICOS s.r.l.s, Via Amico Canobio 4/6, 28100 Novara, Italy.
Dianzani C; Department of Scienza e Tecnologia del Farmaco, University of Turin, 10125 Turin, Italy.
Stoppa I; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.
Monge C; Department of Scienza e Tecnologia del Farmaco, University of Turin, 10125 Turin, Italy.
Sutti S; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.
Sblattero D; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Puricelli C; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.; Clinical Biochemistry Laboratory, Maggiore della Carità University Hospital, 28100 Novara, Italy.
Rolla R; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.; Clinical Biochemistry Laboratory, Maggiore della Carità University Hospital, 28100 Novara, Italy.
Dianzani U; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.; Clinical Biochemistry Laboratory, Maggiore della Carità University Hospital, 28100 Novara, Italy.
Boggio E; Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.; NOVAICOS s.r.l.s, Via Amico Canobio 4/6, 28100 Novara, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 02; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-10*
Interleukin-6*
Humans ; Inducible T-Cell Co-Stimulator Protein ; Lipopolysaccharides/pharmacology ; Macrophages
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Icos gene disruption in non-obese diabetic mice elicits myositis associated with anti-troponin T3 autoantibodies.
Autorzy:
Bourdenet G; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Pileyre B; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Drouot L; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Martinet J; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.; CHU de Rouen, Departement of Immunology and Biotherapy, Rouen, France.
Bécourt C; Cochin Institute, INSERM U1016, Paris, France.
Carrette M; CHU de Rouen, Departement of Immunology and Biotherapy, Rouen, France.
Riou G; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Bergua C; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Jaworski T; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Chan P; Univ Rouen Normandie, INSERM US 51, CNRS UAR 2026, HeRacLeS-PISSARO, Rouen, France.
Jean L; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Fréret M; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.; CHU de Rouen, Department of Rheumatology, Rouen, France.
Cosette P; Univ Rouen Normandie, INSERM US 51, CNRS UAR 2026, HeRacLeS-PISSARO, Rouen, France.; Univ Rouen Normandie, PISSARO, CNRS UMR6270, Rouen, France.
Boitard C; Cochin Institute, INSERM U1016, Paris, France.
Abad C; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.
Boyer O; Univ Rouen Normandie, INSERM U1234, FOCIS Center of Excellence PAn'THER, Rouen, France.; CHU de Rouen, Departement of Immunology and Biotherapy, Rouen, France.
Pokaż więcej
Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2023 Feb; Vol. 49 (1), pp. e12889.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Experimental*
Myositis*
Animals ; Mice ; Mice, Inbred NOD ; Autoantibodies ; Troponin T ; Inducible T-Cell Co-Stimulator Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exosome miR-27a-3p secreted from adipocytes targets ICOS to promote antitumor immunity in lung adenocarcinoma.
Autorzy:
Fan X; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Wang J; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Qin T; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Zhang Y; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Liu W; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Jiang K; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Huang D; Department of Thoracic Oncology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Pokaż więcej
Źródło:
Thoracic cancer [Thorac Cancer] 2020 Jun; Vol. 11 (6), pp. 1453-1464. Date of Electronic Publication: 2020 Mar 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma of Lung/*immunology
Adipocytes/*metabolism
Biomarkers, Tumor/*metabolism
Exosomes/*genetics
Inducible T-Cell Co-Stimulator Protein/*metabolism
Lung Neoplasms/*immunology
MicroRNAs/*genetics
Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/metabolism ; Adenocarcinoma of Lung/pathology ; Adipocytes/immunology ; Aged ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; Cell Proliferation ; Female ; Follow-Up Studies ; Humans ; Inducible T-Cell Co-Stimulator Protein/genetics ; Inducible T-Cell Co-Stimulator Protein/immunology ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Obesity/physiopathology ; Prognosis ; T-Lymphocytes/immunology ; Tumor Cells, Cultured ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Osteopontin binds ICOSL promoting tumor metastasis.
Autorzy:
Raineri D; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Dianzani C; Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, 10125, Torino, Italy.
Cappellano G; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy. .; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Università del Piemonte Orientale, 28100, Novara, Italy. .
Maione F; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Baldanzi G; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Department of Translational Medicine, University of Piemonte Orientale, 28100, Novara, Italy.
Iacobucci I; CEINGE Advanced Biotechnologies, 80145, Naples, Italy.; Dipartimento di Scienze Chimiche, Università di Napoli 'Federico II', 80125, Napoli, Italy.
Clemente N; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Baldone G; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Boggio E; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Gigliotti CL; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Boldorini R; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Laboratorio di Biochimica Clinica, Dipartimento di Scienze della Salute, AOU Maggiore della Carità, Università del Piemonte Orientale, Corso Mazzini 18, 28100, Novara, Italy.
Rojo JM; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), 28040, Madrid, Spain.
Monti M; CEINGE Advanced Biotechnologies, 80145, Naples, Italy.; Dipartimento di Scienze Chimiche, Università di Napoli 'Federico II', 80125, Napoli, Italy.
Birolo L; Dipartimento di Scienze Chimiche, Università di Napoli 'Federico II', 80125, Napoli, Italy.
Dianzani U; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Laboratorio di Biochimica Clinica, Dipartimento di Scienze della Salute, AOU Maggiore della Carità, Università del Piemonte Orientale, Corso Mazzini 18, 28100, Novara, Italy.
Chiocchetti A; Dipartimento di Scienze della Salute, Interdisciplinary Research Center of Autoimmune Diseases-IRCAD, Università del Piemonte Orientale, 28100, Novara, Italy.; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Pokaż więcej
Źródło:
Communications biology [Commun Biol] 2020 Oct 26; Vol. 3 (1), pp. 615. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Movement/*physiology
Inducible T-Cell Co-Stimulator Ligand/*metabolism
Osteopontin/*metabolism
Animals ; Breast Neoplasms/pathology ; Breast Neoplasms/prevention & control ; CHO Cells ; Cell Line, Tumor ; Cricetulus ; Female ; Gene Silencing ; Human Umbilical Vein Endothelial Cells ; Humans ; Inducible T-Cell Co-Stimulator Ligand/genetics ; Mice ; Neoplasm Metastasis/prevention & control ; Neoplasms, Experimental
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain.
Autorzy:
O'Brien CA; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA, United States of America.
Harris TH; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Jan 24; Vol. 15 (1), pp. e0228251. Date of Electronic Publication: 2020 Jan 24 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Brain/*metabolism
Inducible T-Cell Co-Stimulator Protein/*genetics
Toxoplasmosis/*pathology
Animals ; Antibodies, Protozoan/blood ; Brain/cytology ; Brain/immunology ; Disease Models, Animal ; Forkhead Transcription Factors/metabolism ; Inducible T-Cell Co-Stimulator Protein/deficiency ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Interleukin-2 Receptor alpha Subunit/metabolism ; Leukocytes, Mononuclear/cytology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mutagenesis, Site-Directed ; Phosphatidylinositol 3-Kinases/metabolism ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Toxoplasmosis/metabolism ; Toxoplasmosis/parasitology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 4598

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies