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    Tytuł:
    A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.
    Autorzy:
    Stoneham CA; Department of Medicine, University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System, La Jolla, California, United States of America.
    Langer S; Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
    De Jesus PD; Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
    Wozniak JM; Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America.
    Lapek J; Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America.
    Deerinck T; National Center for Microscopy and Imaging Research, Center for Research on Biological Systems, University of California, San Diego, School of Medicine, La Jolla, California, United States of America.
    Thor A; National Center for Microscopy and Imaging Research, Center for Research on Biological Systems, University of California, San Diego, School of Medicine, La Jolla, California, United States of America.
    Pache L; Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
    Chanda SK; Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
    Gonzalez DJ; Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America.
    Ellisman M; National Center for Microscopy and Imaging Research, Center for Research on Biological Systems, University of California, San Diego, School of Medicine, La Jolla, California, United States of America.; Department of Neurosciences, University of California, San Diego School of Medicine, La Jolla, California, United States of America.
    Guatelli J; Department of Medicine, University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System, La Jolla, California, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2021 Nov 29; Vol. 17 (11), pp. e1009409. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Endosomal Sorting Complexes Required for Transport/*metabolism
    HIV Infections/*virology
    Human Immunodeficiency Virus Proteins/*metabolism
    Protein Tyrosine Phosphatases, Non-Receptor/*metabolism
    Proteome/*metabolism
    Sorting Nexins/*metabolism
    Vesicular Transport Proteins/*metabolism
    Viral Regulatory and Accessory Proteins/*metabolism
    Viroporin Proteins/*metabolism
    Endosomal Sorting Complexes Required for Transport/genetics ; HIV Infections/genetics ; HIV Infections/metabolism ; HIV-1/physiology ; HeLa Cells ; Human Immunodeficiency Virus Proteins/genetics ; Humans ; Microscopy, Electron ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Protein Transport ; Protein Tyrosine Phosphatases, Non-Receptor/genetics ; Proteome/analysis ; Sorting Nexins/chemistry ; Sorting Nexins/genetics ; Vesicular Transport Proteins/chemistry ; Vesicular Transport Proteins/genetics ; Viral Regulatory and Accessory Proteins/genetics ; Viroporin Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.
    Autorzy:
    Park SH; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
    Siddiqi H; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
    Castro DV; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
    De Angelis AA; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
    Oom AL; Department of Medicine, University of California San Diego, La Jolla, California, United States of America.
    Stoneham CA; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, United States of America.
    Lewinski MK; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, United States of America.
    Clark AE; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, United States of America.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America.
    Croker BA; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.
    Carlin AF; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, United States of America.
    Guatelli J; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, United States of America.
    Opella SJ; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2021 May 18; Vol. 17 (5), pp. e1009519. Date of Electronic Publication: 2021 May 18 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    COVID-19 Drug Treatment*
    Amiloride/*pharmacology
    Coronavirus Envelope Proteins/*metabolism
    SARS-CoV-2/*drug effects
    SARS-CoV-2/*metabolism
    Amiloride/pharmacokinetics ; Animals ; Antiviral Agents/pharmacology ; Binding Sites/drug effects ; COVID-19/virology ; Chlorocebus aethiops ; Coronavirus Envelope Proteins/chemistry ; Humans ; Ion Channels/metabolism ; Nuclear Magnetic Resonance, Biomolecular ; Protein Binding/drug effects ; Protein Conformation/drug effects ; Protein Domains ; Vero Cells ; Virus Assembly/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins.
    Autorzy:
    Ramirez PW; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
    Sharma S; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
    Singh R; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
    Stoneham CA; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
    Vollbrecht T; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
    Guatelli J; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA. .; VA San Diego Healthcare System, San Diego, CA 92161, USA. .
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    Źródło:
    Cells [Cells] 2019 Sep 02; Vol. 8 (9). Date of Electronic Publication: 2019 Sep 02.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Review
    MeSH Terms:
    Antigens, CD/*metabolism
    HIV Infections/*immunology
    HIV-1/*pathogenicity
    Membrane Glycoproteins/*metabolism
    Membrane Proteins/*metabolism
    Viral Regulatory and Accessory Proteins/*metabolism
    Animals ; GPI-Linked Proteins/metabolism ; HIV Infections/virology ; HIV-1/metabolism ; Host-Pathogen Interactions ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Endocytic activity of HIV-1 Vpu: Phosphoserine-dependent interactions with clathrin adaptors.
    Autorzy:
    Stoneham CA; Department of Medicine, University of California at San Diego, La Jolla, California.; VA San Diego Healthcare System, San Diego, California.
    Singh R; Department of Medicine, University of California at San Diego, La Jolla, California.; VA San Diego Healthcare System, San Diego, California.
    Jia X; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.
    Xiong Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.
    Guatelli J; Department of Medicine, University of California at San Diego, La Jolla, California.; VA San Diego Healthcare System, San Diego, California.
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    Źródło:
    Traffic (Copenhagen, Denmark) [Traffic] 2017 Aug; Vol. 18 (8), pp. 545-561. Date of Electronic Publication: 2017 Jun 27.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Endocytosis*
    Adaptor Proteins, Vesicular Transport/*metabolism
    Human Immunodeficiency Virus Proteins/*metabolism
    Phosphoserine/*metabolism
    Viral Regulatory and Accessory Proteins/*metabolism
    HeLa Cells ; Humans ; Phosphorylation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Enterohaemorrhagic Escherichia coli inhibits recycling endosome function and trafficking of surface receptors.
    Autorzy:
    Clements A; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK.
    Stoneham CA
    Furniss RC
    Frankel G
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    Źródło:
    Cellular microbiology [Cell Microbiol] 2014 Nov; Vol. 16 (11), pp. 1693-705. Date of Electronic Publication: 2014 Jul 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Host-Pathogen Interactions*
    Endosomes/*drug effects
    Endosomes/*metabolism
    Enterohemorrhagic Escherichia coli/*physiology
    Escherichia coli Proteins/*metabolism
    Membrane Proteins/*metabolism
    Receptors, Transferrin/*metabolism
    ADP-Ribosylation Factor 1/metabolism ; ErbB Receptors/metabolism ; GTPase-Activating Proteins/metabolism ; HeLa Cells ; Humans ; Integrin beta1/metabolism ; Microtubule-Associated Proteins/metabolism ; Protein Binding
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-5 z 5

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