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Wyszukujesz frazę ""Streptococcus pyogenes"" wg kryterium: Temat


Tytuł:
An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis.
Autorzy:
Fabri LV; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Université Libre de Bruxelles, Brussels, Belgium.
Azzopardi KI; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Osowicki J; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia. .; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia. .; Infectious Diseases Unit, Department of General Medicine, The Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia. .
Frost HR; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Smeesters PR; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Université Libre de Bruxelles, Brussels, Belgium.; Academic Children Hospital Queen Fabiola, Université Libre de Bruxelles, Brussels, Belgium.; Molecular Bacteriology Laboratory, Université Libre de Bruxelles, Brussels, Belgium.
Steer AC; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.; Infectious Diseases Unit, Department of General Medicine, The Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2021 May 21; Vol. 21 (1), pp. 463. Date of Electronic Publication: 2021 May 21.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Bacterial Load*
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Pharyngitis/*microbiology
Real-Time Polymerase Chain Reaction/*methods
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*genetics
Adult ; DNA, Bacterial/genetics ; DNA, Bacterial/isolation & purification ; Follow-Up Studies ; Healthy Volunteers ; Humans ; RNA, Bacterial/genetics ; RNA, Bacterial/isolation & purification ; Sensitivity and Specificity ; Streptococcus pyogenes/classification ; Streptococcus pyogenes/isolation & purification
Czasopismo naukowe
Tytuł:
Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology.
Autorzy:
Khakzad H; Équipe Signalisation Calcique et Infections Microbiennes, École Normale Supérieure Paris-Saclay, Gif-sur-Yvette, France.; Institut National de la Santé et de la Recherche Gif-sur-Yvette, France.
Happonen L; Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden.
Karami Y; Structural Bioinformatics Unit, Department of Structural Biology and Chemistry, C3BI, Institut Pasteur, CNRS UMR3528, Paris, France.
Chowdhury S; Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden.
Bergdahl GE; Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden.
Nilges M; Structural Bioinformatics Unit, Department of Structural Biology and Chemistry, C3BI, Institut Pasteur, CNRS UMR3528, Paris, France.
Tran Van Nhieu G; Équipe Signalisation Calcique et Infections Microbiennes, École Normale Supérieure Paris-Saclay, Gif-sur-Yvette, France.; Institut National de la Santé et de la Recherche Gif-sur-Yvette, France.
Malmström J; Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden.
Malmström L; Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 Jan 07; Vol. 17 (1), pp. e1008169. Date of Electronic Publication: 2021 Jan 07 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial*/chemistry
Antigens, Bacterial*/metabolism
Bacterial Outer Membrane Proteins*/chemistry
Bacterial Outer Membrane Proteins*/metabolism
Carrier Proteins*/chemistry
Carrier Proteins*/metabolism
Immunoglobulin G*/chemistry
Immunoglobulin G*/metabolism
Streptococcus pyogenes*/chemistry
Streptococcus pyogenes*/metabolism
Host-Pathogen Interactions ; Humans ; Mass Spectrometry ; Molecular Dynamics Simulation ; Phagocytosis ; Protein Binding ; Virulence Factors/chemistry ; Virulence Factors/metabolism
Czasopismo naukowe
Tytuł:
Immunotherapy targeting the Streptococcus pyogenes M protein or streptolysin O to treat or prevent influenza A superinfection.
Autorzy:
Herrera AL; Division of Basic Biomedical Sciences, The Sanford School of Medicine of the University of South Dakota, Vermillion, SD, United States of America.
Van Hove C; Division of Basic Biomedical Sciences, The Sanford School of Medicine of the University of South Dakota, Vermillion, SD, United States of America.
Hanson M; Division of Basic Biomedical Sciences, The Sanford School of Medicine of the University of South Dakota, Vermillion, SD, United States of America.
Dale JB; Department of Medicine, Division of Infectious Diseases, University of Tennessee Health Science Center, Memphis, TN, United States of America.
Tweten RK; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States of America.
Huber VC; Division of Basic Biomedical Sciences, The Sanford School of Medicine of the University of South Dakota, Vermillion, SD, United States of America.
Diel D; Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD, United States of America.
Chaussee MS; Division of Basic Biomedical Sciences, The Sanford School of Medicine of the University of South Dakota, Vermillion, SD, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Jun 23; Vol. 15 (6), pp. e0235139. Date of Electronic Publication: 2020 Jun 23 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial/*immunology
Bacterial Outer Membrane Proteins/*immunology
Carrier Proteins/*immunology
Immunotherapy/*methods
Influenza A virus/*immunology
Orthomyxoviridae Infections/*immunology
Streptococcal Infections/*immunology
Streptococcus pyogenes/*immunology
Streptolysins/*immunology
Animals ; Antibodies, Bacterial/blood ; Antibodies, Bacterial/immunology ; Antigens, Bacterial/metabolism ; Bacterial Outer Membrane Proteins/antagonists & inhibitors ; Bacterial Outer Membrane Proteins/metabolism ; Bacterial Proteins/antagonists & inhibitors ; Bacterial Proteins/immunology ; Bacterial Proteins/metabolism ; Carrier Proteins/antagonists & inhibitors ; Carrier Proteins/metabolism ; Coinfection/microbiology ; Coinfection/therapy ; Coinfection/virology ; Female ; Host-Pathogen Interactions/drug effects ; Host-Pathogen Interactions/immunology ; Humans ; Immune Sera/immunology ; Immune Sera/pharmacology ; Influenza A virus/physiology ; Mice, Inbred BALB C ; Orthomyxoviridae Infections/therapy ; Orthomyxoviridae Infections/virology ; Rabbits ; Streptococcal Infections/microbiology ; Streptococcal Infections/therapy ; Streptococcus pyogenes/metabolism ; Streptococcus pyogenes/physiology ; Streptolysins/antagonists & inhibitors ; Streptolysins/metabolism ; Superinfection/microbiology ; Superinfection/therapy ; Superinfection/virology
Czasopismo naukowe
Tytuł:
Cold Atmospheric Plasma Disarms M1 Protein, an Important Streptococcal Virulence Factor.
Autorzy:
Persson ST; Division of Infection Medicine, Department of Clinical Sciences, Lund University Biomedical Center, Lund, Sweden, .
Ekström S; Swedish National Infrastructure for Biological Mass Spectrometry (BioMS), Lund University, Lund, Sweden.
Papareddy P; Division of Infection Medicine, Department of Clinical Sciences, Lund University Biomedical Center, Lund, Sweden.
Herwald H; Division of Infection Medicine, Department of Clinical Sciences, Lund University Biomedical Center, Lund, Sweden.
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Źródło:
Journal of innate immunity [J Innate Immun] 2020; Vol. 12 (4), pp. 277-290. Date of Electronic Publication: 2019 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Streptococcus pyogenes*/immunology
Streptococcus pyogenes*/pathogenicity
Antigens, Bacterial/*immunology
Bacterial Outer Membrane Proteins/*immunology
Carrier Proteins/*immunology
Plasma Gases/*chemistry
Virulence Factors/*immunology
Cell Line, Transformed ; Humans ; Oxidation-Reduction
Czasopismo naukowe
Tytuł:
Streptococcal superantigens and the return of scarlet fever.
Autorzy:
Hurst JR; Department of Microbiology and Immunology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada.
Brouwer S; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, St. Lucia, Queensland, Australia.
Walker MJ; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, St. Lucia, Queensland, Australia.
McCormick JK; Department of Microbiology and Immunology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada.; Lawson Health Research Institute, London, Ontario, Canada.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Dec 30; Vol. 17 (12), pp. e1010097. Date of Electronic Publication: 2021 Dec 30 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Antigens, Bacterial/*immunology
Scarlet Fever/*immunology
Streptococcus pyogenes/*immunology
Superantigens/*immunology
Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł:
Changes in emm types and superantigen gene content of Streptococcus pyogenes causing invasive infections in Portugal.
Autorzy:
Friães A; Instituto de Microbiologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal. .
Melo-Cristino J; Instituto de Microbiologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Ramirez M; Instituto de Microbiologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
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Corporate Authors:
Portuguese Group for the Study of Streptococcal Infections
Źródło:
Scientific reports [Sci Rep] 2019 Dec 02; Vol. 9 (1), pp. 18051. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Bacterial Agents/*pharmacology
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Carrier Proteins/*genetics
Streptococcal Infections/*drug therapy
Streptococcus pyogenes/*classification
Superantigens/*genetics
Adolescent ; Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Antigens, Bacterial/isolation & purification ; Bacterial Outer Membrane Proteins/isolation & purification ; Carrier Proteins/isolation & purification ; Child ; Child, Preschool ; DNA, Bacterial/genetics ; DNA, Bacterial/isolation & purification ; Drug Resistance, Bacterial/genetics ; Female ; Humans ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Molecular Epidemiology ; Molecular Typing ; Portugal/epidemiology ; Streptococcal Infections/epidemiology ; Streptococcal Infections/immunology ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/drug effects ; Streptococcus pyogenes/isolation & purification ; Streptococcus pyogenes/physiology ; Superantigens/immunology ; Superantigens/isolation & purification ; Young Adult
Czasopismo naukowe
Tytuł:
Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease.
Autorzy:
Giffard PM; Menzies School of Health Research, Division of Global and Tropical Health, Darwin, Australia.; College of Health and Human Sciences, Charles Darwin University, Darwin, Australia.
Tong SYC; Menzies School of Health Research, Division of Global and Tropical Health, Darwin, Australia.; Victorian Infectious Disease Service, The Royal Melbourne Hospital, and Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Holt DC; Menzies School of Health Research, Division of Global and Tropical Health, Darwin, Australia.; College of Health and Human Sciences, Charles Darwin University, Darwin, Australia.
Ralph AP; Menzies School of Health Research, Division of Global and Tropical Health, Darwin, Australia.; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.
Currie BJ; Menzies School of Health Research, Division of Global and Tropical Health, Darwin, Australia.; Division of Medicine, Royal Darwin Hospital, Darwin, Australia.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Jul 03; Vol. 13 (7), pp. e0007511. Date of Electronic Publication: 2019 Jul 03 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Streptococcus pyogenes*
Antigens, Bacterial/*immunology
Bacterial Outer Membrane Proteins/*immunology
Carrier Proteins/*immunology
Rheumatic Heart Disease/*microbiology
Streptococcal Infections/*prevention & control
Streptococcal Vaccines/*therapeutic use
Humans ; Northern Territory/epidemiology ; Pharyngitis/epidemiology ; Pharyngitis/microbiology ; Prevalence ; Rheumatic Heart Disease/epidemiology ; Rheumatic Heart Disease/prevention & control ; Skin/microbiology ; Streptococcal Infections/complications ; Streptococcal Infections/epidemiology ; Streptococcal Vaccines/immunology
Czasopismo naukowe
Tytuł:
Nonimmune antibody interactions of Group A Streptococcus M and M-like proteins.
Autorzy:
Mills JO; Department of Chemistry & Biochemistry, La Jolla, California, United States of America.
Ghosh P; Department of Chemistry & Biochemistry, La Jolla, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Feb 25; Vol. 17 (2), pp. e1009248. Date of Electronic Publication: 2021 Feb 25 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Antibodies, Monoclonal/*metabolism
Antigens, Bacterial/*metabolism
Bacterial Outer Membrane Proteins/*metabolism
Carrier Proteins/*metabolism
Immunoglobulin Fc Fragments/*metabolism
Streptococcal Infections/*metabolism
Streptococcus pyogenes/*metabolism
Animals ; Humans ; Streptococcal Infections/microbiology
Czasopismo naukowe
Tytuł:
A multivalent T-antigen-based vaccine for Group A Streptococcus.
Autorzy:
Loh JMS; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand. .; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand. .
Rivera-Hernandez T; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; Cátedras CONACYT-Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
McGregor R; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
Khemlani AHJ; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
Tay ML; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
Cork AJ; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
M Raynes J; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.; Monash University, Clayton Campus, Melbourne, VIC, Australia.
Moreland NJ; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
Walker MJ; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
Proft T; Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand. .; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand. .
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Źródło:
Scientific reports [Sci Rep] 2021 Feb 23; Vol. 11 (1), pp. 4353. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial/*immunology
Streptococcal Vaccines/*immunology
Streptococcus pyogenes/*immunology
Animals ; Antigens, Bacterial/chemistry ; Antigens, Bacterial/genetics ; Cell Line, Tumor ; Humans ; Immunogenicity, Vaccine ; Mice ; Rabbits ; Vaccines, Combined/immunology ; Vaccines, Synthetic/immunology
Czasopismo naukowe
Tytuł:
Modelling invasive group A streptococcal disease using bioluminescence.
Autorzy:
Lamb LE; Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, UK.; Royal Centre Defence Medicine, Academia and Research, University of Birmingham, Birmingham, B15 2SQ, UK.
Zhi X; Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, UK.
Alam F; Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, UK.
Pyzio M; Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, UK.
Scudamore CL; MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK.
Wiles S; Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, UK.; Bioluminescent Superbugs Lab, Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Sriskandan S; Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, UK. .
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Źródło:
BMC microbiology [BMC Microbiol] 2018 Jun 19; Vol. 18 (1), pp. 60. Date of Electronic Publication: 2018 Jun 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Carrier Proteins/*genetics
Luminescent Proteins/*metabolism
Respiratory Tract Infections/*microbiology
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*pathogenicity
Animals ; Disease Models, Animal ; Female ; Genetic Fitness ; Humans ; Luminescent Measurements ; Luminescent Proteins/genetics ; Mice ; Operon ; Streptococcus pyogenes/genetics
Czasopismo naukowe
Tytuł:
Group A streptococcal M-protein specific antibodies and T-cells drive the pathology observed in the rat autoimmune valvulitis model.
Autorzy:
Sikder S; a College of Public Health Medical and Veterinary Sciences , Australian Institute of Tropical Health and Medicine, James Cook University , Townsville , Australia.; b Department of Medicine and Surgery , Chittagong Veterinary and Animal Sciences University , Chittagong , Bangladesh.
Price G; a College of Public Health Medical and Veterinary Sciences , Australian Institute of Tropical Health and Medicine, James Cook University , Townsville , Australia.
Alim MA; a College of Public Health Medical and Veterinary Sciences , Australian Institute of Tropical Health and Medicine, James Cook University , Townsville , Australia.; c Department of Pathology and Parasitology , Chittagong Veterinary and Animal Sciences University , Chittagong , Bangladesh.
Gautam A; d The Townsville Hospital , Townsville , Australia.
Scott Simpson R; e Barwon Health , Geelong , Australia.
Margaret Rush C; a College of Public Health Medical and Veterinary Sciences , Australian Institute of Tropical Health and Medicine, James Cook University , Townsville , Australia.
Lee Govan B; a College of Public Health Medical and Veterinary Sciences , Australian Institute of Tropical Health and Medicine, James Cook University , Townsville , Australia.
Ketheesan N; f School of Science & Technology , University of New England , Armidale , Australia.
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Źródło:
Autoimmunity [Autoimmunity] 2019 Mar; Vol. 52 (2), pp. 78-87. Date of Electronic Publication: 2019 May 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autoimmune Diseases*/chemically induced
Autoimmune Diseases*/immunology
Autoimmune Diseases*/pathology
Heart Valve Diseases*/chemically induced
Heart Valve Diseases*/immunology
Heart Valve Diseases*/pathology
Rheumatic Heart Disease*/chemically induced
Rheumatic Heart Disease*/immunology
Rheumatic Heart Disease*/pathology
Streptococcus pyogenes*
T-Lymphocytes*/immunology
T-Lymphocytes*/pathology
Antigens, Bacterial/*toxicity
Bacterial Outer Membrane Proteins/*toxicity
Carrier Proteins/*toxicity
Animals ; Antigens, Bacterial/immunology ; Bacterial Outer Membrane Proteins/immunology ; Carrier Proteins/immunology ; Female ; Rats ; Rats, Inbred Lew
Czasopismo naukowe
Tytuł:
Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus.
Autorzy:
Afshar B; a Department of Medicine , Imperial College London , London , U.K.; b National Infection Service, Public Health England , London , U.K.
Turner CE; a Department of Medicine , Imperial College London , London , U.K.
Lamagni TL; b National Infection Service, Public Health England , London , U.K.
Smith KC; c Pathology and Pathogen Biology , Royal Veterinary College, University of London , Hertfordshire , U.K.
Al-Shahib A; b National Infection Service, Public Health England , London , U.K.
Underwood A; b National Infection Service, Public Health England , London , U.K.
Holden MTG; d Pathogen Genomics , The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus , Hinxton , Cambridge , U.K.; e School of Medicine , University of St Andrews , St. Andrews , U.K.
Efstratiou A; b National Infection Service, Public Health England , London , U.K.
Sriskandan S; a Department of Medicine , Imperial College London , London , U.K.
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Źródło:
Virulence [Virulence] 2017 Oct 03; Vol. 8 (7), pp. 1390-1400. Date of Electronic Publication: 2017 May 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Carrier Proteins/*genetics
Nasopharyngeal Diseases/*microbiology
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*physiology
Animals ; Antigens, Bacterial/metabolism ; Bacterial Outer Membrane Proteins/metabolism ; Carrier Proteins/metabolism ; Female ; Genotype ; Humans ; Mice ; Moths ; Nasopharyngeal Diseases/epidemiology ; Prophages/genetics ; Prophages/physiology ; Streptococcal Infections/epidemiology ; Streptococcus pyogenes/genetics ; Streptococcus pyogenes/pathogenicity ; Streptococcus pyogenes/virology ; United Kingdom/epidemiology ; Virulence
Czasopismo naukowe
Tytuł:
Leucocyte recruitment and molecular fortification of keratinocytes triggered by streptococcal M1 protein.
Autorzy:
Persson ST; Division of Infection Medicine, Department of Clinical Sciences, Biomedical Center, Lund University, Lund, Sweden.
Hauri S; Division of Infection Medicine, Department of Clinical Sciences, Biomedical Center, Lund University, Lund, Sweden.
Malmström J; Division of Infection Medicine, Department of Clinical Sciences, Biomedical Center, Lund University, Lund, Sweden.
Herwald H; Division of Infection Medicine, Department of Clinical Sciences, Biomedical Center, Lund University, Lund, Sweden.
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Źródło:
Cellular microbiology [Cell Microbiol] 2018 Jan; Vol. 20 (1). Date of Electronic Publication: 2017 Oct 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Bacterial/*immunology
Bacterial Outer Membrane Proteins/*immunology
Carrier Proteins/*immunology
Cellulitis/*pathology
Fasciitis, Necrotizing/*pathology
Leukocytes/*immunology
Streptococcal Infections/*pathology
Streptococcus pyogenes/*pathogenicity
Cell Line ; Cell Movement/physiology ; Cell Proliferation ; Cellulitis/microbiology ; Fasciitis, Necrotizing/microbiology ; Humans ; Keratinocytes ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/metabolism ; Virulence Factors
Czasopismo naukowe
Tytuł:
MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression.
Autorzy:
Shaler CR; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.
Choi J; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.
Rudak PT; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.
Memarnejadian A; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.
Szabo PA; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.
Tun-Abraham ME; Division of General Surgery, Department of Surgery, Western University, London, Ontario, Canada.
Rossjohn J; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom.
Corbett AJ; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
McCluskey J; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
McCormick JK; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.; Centre for Human Immunology, Western University, London, Ontario, Canada.; Lawson Health Research Institute, London, Ontario, Canada.
Lantz O; Laboratoire d'Immunologie and INSERM U932, Institut Curie, Paris, France.
Hernandez-Alejandro R; Division of General Surgery, Department of Surgery, Western University, London, Ontario, Canada.; Division of Transplantation, Department of Surgery, University of Rochester Medical Center, Rochester, New York, United States of America.
Haeryfar SMM; Department of Microbiology and Immunology, Western University, London, Ontario, Canada.; Centre for Human Immunology, Western University, London, Ontario, Canada.; Lawson Health Research Institute, London, Ontario, Canada.; Division of Clinical Immunology and Allergy, Department of Medicine, Western University, London, Ontario, Canada.
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Źródło:
PLoS biology [PLoS Biol] 2017 Jun 20; Vol. 15 (6), pp. e2001930. Date of Electronic Publication: 2017 Jun 20 (Print Publication: 2017).
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Clonal Anergy*/drug effects
Models, Immunological*
Antigens, Bacterial/*toxicity
Mucosal-Associated Invariant T Cells/*immunology
Staphylococcus aureus/*immunology
Streptococcus pyogenes/*immunology
Superantigens/*toxicity
Animals ; Antigens, Bacterial/metabolism ; Bone Marrow Cells/cytology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/immunology ; Bone Marrow Cells/metabolism ; Cell Line ; Cells, Cultured ; Crosses, Genetic ; Enterotoxins/metabolism ; Enterotoxins/toxicity ; Female ; Humans ; Hybridomas ; Immunity, Innate ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/metabolism ; Lymphocyte Activation/drug effects ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Mice, Transgenic ; Mucosal-Associated Invariant T Cells/cytology ; Mucosal-Associated Invariant T Cells/drug effects ; Mucosal-Associated Invariant T Cells/metabolism ; Specific Pathogen-Free Organisms ; Staphylococcus aureus/metabolism ; Streptococcus pyogenes/metabolism ; Superantigens/metabolism ; Transplantation Chimera/blood ; Transplantation Chimera/immunology ; Transplantation Chimera/metabolism
Czasopismo naukowe
Tytuł:
Relation between emm types and virulence gene profiles among Bulgarian Streptococcus pyogenes clinical isolates.
Autorzy:
Gergova R; a Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
Muhtarova A; a Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
Mitov I; a Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
Setchanova L; a Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
Mihova K; b Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
Kaneva R; b Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
Markovska R; a Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia , Sofia , Bulgaria.
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Źródło:
Infectious diseases (London, England) [Infect Dis (Lond)] 2019 Sep; Vol. 51 (9), pp. 668-675. Date of Electronic Publication: 2019 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Carrier Proteins/*genetics
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*genetics
Streptococcus pyogenes/*pathogenicity
Virulence Factors/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antigens, Bacterial/classification ; Bacterial Outer Membrane Proteins/classification ; Bulgaria ; Carrier Proteins/classification ; Child ; Child, Preschool ; Genotype ; Humans ; Infant ; Middle Aged ; Sequence Analysis, DNA ; Virulence ; Young Adult
Czasopismo naukowe
Tytuł:
Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones.
Autorzy:
Döhrmann S; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.
LaRock CN; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.
Anderson EL; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.
Cole JN; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.
Ryali B; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.
Stewart C; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
Nonejuie P; Department of Biological Sciences, University of California San Diego, La Jolla, California, United States of America.
Pogliano J; Department of Biological Sciences, University of California San Diego, La Jolla, California, United States of America.
Corriden R; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.; Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America.
Ghosh P; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America.
Nizet V; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.; Department of Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America.; Rady Children's Hospital, San Diego, California, United States of America.
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 21; Vol. 7, pp. 43039. Date of Electronic Publication: 2017 Feb 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Immune Evasion*
Antigens, Bacterial/*physiology
Bacterial Outer Membrane Proteins/*physiology
Carrier Proteins/*physiology
Histones/*metabolism
Neutrophils/*immunology
Streptococcal Infections/*microbiology
Streptococcus pyogenes/*physiology
Antigens, Bacterial/metabolism ; Bacterial Outer Membrane Proteins/metabolism ; Carrier Proteins/metabolism ; Humans ; Neutrophils/metabolism ; Streptococcal Infections/metabolism ; Streptococcus pyogenes/metabolism ; Streptococcus pyogenes/pathogenicity ; Virulence Factors/metabolism ; Virulence Factors/physiology
Czasopismo naukowe
Tytuł:
Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice.
Autorzy:
Feng W; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana 59718, United States of America.
Liu M; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana 59718, United States of America.
Chen DG; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana 59718, United States of America.
Yiu R; Harborview Medical Center Clinical Microbiology Laboratory and University of Washington School of Medicine, Seattle, Washington, United States of America.
Fang FC; Harborview Medical Center Clinical Microbiology Laboratory and University of Washington School of Medicine, Seattle, Washington, United States of America.
Lei B; Department of Microbiology and Immunology, Montana State University, Bozeman, Montana 59718, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Sep 09; Vol. 11 (9), pp. e0162742. Date of Electronic Publication: 2016 Sep 09 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Bacterial/*metabolism
Bacterial Outer Membrane Proteins/*metabolism
Bacterial Proteins/*metabolism
Carrier Proteins/*metabolism
Mutation/*genetics
Pharynx/*microbiology
Streptococcus pyogenes/*isolation & purification
Streptococcus pyogenes/*metabolism
Alleles ; Animals ; Female ; Genotype ; Mice, Inbred C57BL ; Pharynx/pathology ; Phenotype ; Streptococcal Infections/microbiology ; Streptococcal Infections/pathology ; Streptococcus pyogenes/genetics ; Subcutaneous Tissue/microbiology ; Subcutaneous Tissue/pathology
Czasopismo naukowe
Tytuł:
Predicted Coverage and Immuno-Safety of a Recombinant C-Repeat Region Based Streptococcus pyogenes Vaccine Candidate.
Autorzy:
McNeilly C; Bacterial Pathogenesis Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Rd, Herston, QLD, 4006, Australia.
Cosh S; Bacterial Pathogenesis Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Rd, Herston, QLD, 4006, Australia.
Vu T; Bacterial Pathogenesis Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Rd, Herston, QLD, 4006, Australia.
Nichols J; Inflammation and Healing Research Cluster, School of Health and Sport Sciences, University of the Sunshine Coast, Maroochydore, QLD, 4558, Australia.
Henningham A; Australian Infectious Disease Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, 4072, Australia.
Hofmann A; Structural Chemistry Program, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, and Queensland Tropical Health Alliance, Smithfield, QLD, Australia.
Fane A; Australian Institute of Tropical Medicine, James Cook University, Townsville, QLD, 4811, Australia.
Smeesters PR; Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculté des Sciences, Université Libre de Bruxelles, Gosselies, Belgium, and Murdoch Children Research Institute, Melbourne, VIC, 3052, Australia.
Rush CM; Australian Institute of Tropical Medicine, James Cook University, Townsville, QLD, 4811, Australia.
Hafner LM; School of Biomedical Sciences, Faculty of Health & Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology, Brisbane, QLD, 4001, Australia.
Ketheesan N; Australian Institute of Tropical Medicine, James Cook University, Townsville, QLD, 4811, Australia.
Sriprakash KS; Bacterial Pathogenesis Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Rd, Herston, QLD, 4006, Australia.
McMillan DJ; Bacterial Pathogenesis Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Rd, Herston, QLD, 4006, Australia.; Inflammation and Healing Research Cluster, School of Health and Sport Sciences, University of the Sunshine Coast, Maroochydore, QLD, 4558, Australia.
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Źródło:
PloS one [PLoS One] 2016 Jun 16; Vol. 11 (6), pp. e0156639. Date of Electronic Publication: 2016 Jun 16 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Bacterial/*biosynthesis
Antigens, Bacterial/*immunology
Rheumatic Heart Disease/*prevention & control
Streptococcal Infections/*prevention & control
Streptococcal Vaccines/*administration & dosage
Streptococcus pyogenes/*immunology
Adjuvants, Immunologic/administration & dosage ; Alum Compounds/administration & dosage ; Animals ; Antigens, Bacterial/genetics ; Collagen/genetics ; Collagen/metabolism ; Female ; Gene Expression ; Heart Valves/drug effects ; Heart Valves/immunology ; Heart Valves/microbiology ; Heart Valves/pathology ; Mice ; Mice, Inbred BALB C ; Myosins/genetics ; Myosins/metabolism ; Rats ; Rats, Inbred Lew ; Repetitive Sequences, Amino Acid ; Rheumatic Heart Disease/immunology ; Rheumatic Heart Disease/microbiology ; Rheumatic Heart Disease/pathology ; Spleen/drug effects ; Spleen/immunology ; Spleen/microbiology ; Spleen/pathology ; Streptococcal Infections/immunology ; Streptococcal Infections/microbiology ; Streptococcal Infections/pathology ; Streptococcal Vaccines/biosynthesis ; Streptococcal Vaccines/immunology ; Streptococcus pyogenes/drug effects ; Streptococcus pyogenes/genetics ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/microbiology ; T-Lymphocytes/pathology ; Vaccines, Synthetic
Czasopismo naukowe
Tytuł:
M types & toxin gene profile of group A streptococci isolated from children in Dibrugarh district of Assam, India.
Autorzy:
Devi U; Regional Medical Research Centre, NE Region (ICMR), Post Box-105, Dibrugarh 786 001, Assam, India.
Borah PK; Regional Medical Research Centre, NE Region (ICMR), Post Box-105, Dibrugarh 786 001, Assam, India.
Malik V; Regional Medical Research Centre, NE Region (ICMR), Post Box-105, Dibrugarh 786 001, Assam, India.
Parida P; Regional Medical Research Centre, NE Region (ICMR), Post Box-105, Dibrugarh 786 001, Assam, India.
Mahanta J; Regional Medical Research Centre, NE Region (ICMR), Post Box-105, Dibrugarh 786 001, Assam, India.
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Źródło:
The Indian journal of medical research [Indian J Med Res] 2016 May; Vol. 143 (5), pp. 659-62.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Carrier Proteins/*genetics
Streptococcal Infections/*genetics
Streptococcus pyogenes/*genetics
Antigens, Bacterial/classification ; Bacterial Outer Membrane Proteins/classification ; Carrier Proteins/classification ; Humans ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/classification ; Streptococcus pyogenes/pathogenicity
Czasopismo naukowe
Tytuł:
Streptococcus pyogenes Pneumonia in Adults: Clinical Presentation and Molecular Characterization of Isolates 2006-2015.
Autorzy:
Tamayo E; Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.
Montes M; Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.; Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain.
Vicente D; Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.; Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain.
Pérez-Trallero E; Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.; Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain.; Medicine Faculty, University of the Basque Country, UPV/EHU, San Sebastián, Spain.
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Źródło:
PloS one [PLoS One] 2016 Mar 30; Vol. 11 (3), pp. e0152640. Date of Electronic Publication: 2016 Mar 30 (Print Publication: 2016).
Typ publikacji:
Clinical Trial; Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Genotype*
Pneumonia, Bacterial*/genetics
Pneumonia, Bacterial*/mortality
Pneumonia, Bacterial*/pathology
Pneumonia, Bacterial*/physiopathology
Streptococcal Infections*/genetics
Streptococcal Infections*/mortality
Streptococcal Infections*/pathology
Streptococcal Infections*/physiopathology
Streptococcus pyogenes*/genetics
Streptococcus pyogenes*/isolation & purification
Antigens, Bacterial/*genetics
Bacterial Outer Membrane Proteins/*genetics
Carrier Proteins/*genetics
Adult ; Female ; Humans ; Male ; Mortality ; Retrospective Studies ; Spain/epidemiology
Czasopismo naukowe

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