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Wyświetlanie 1-17 z 17
Tytuł:
Self-organising human gonads generated by a Matrigel-based gradient system.
Autorzy:
Oliver E; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Alves-Lopes JP; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.; Present address: Wellcome Trust/Cancer Research UK Gurdon Institute, Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Road, Cambridge, CB2 1QN, UK.
Harteveld F; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Mitchell RT; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, EH16 4TJ, UK.; Royal Hospital for Children and Young People, 9 Sciennes Road, Edinburgh, EH9 1LF, Scotland, UK.
Åkesson E; Department of Neurobiology, Care Sciences & Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.; The R&D Unit, Stockholms Sjukhem, Stockholm, Sweden.
Söder O; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, J9:30, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Visionsgatan 4, 17164, Solna, Stockholm, Sweden. jan-bernd.stukenborg@ki.se.
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Źródło:
BMC biology [BMC Biol] 2021 Sep 23; Vol. 19 (1), pp. 212. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sertoli Cells*
Testis*
Animals ; Collagen ; Drug Combinations ; Female ; Gonads ; Humans ; Laminin ; Male ; Proteoglycans ; Rats ; Suspensions
Czasopismo naukowe
Tytuł:
Spermatogonia Loss Correlates with LAMA 1 Expression in Human Prepubertal Testes Stored for Fertility Preservation.
Autorzy:
Kurek M; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
Åkesson E; Division of Neurogeriatrics, Department of Neurobiology Care Sciences & Society, Karolinska Institutet, 141 83 Huddinge, Sweden.; The R & D Unit, Stockholms Sjukhem, 112 19 Stockholm, Sweden.
Yoshihara M; Department of Biosciences and Nutrition, Karolinska Institutet, 141 83 Huddinge, Sweden.
Oliver E; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
Cui Y; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
Becker M; Center of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health, Karolinska Institutet, Centre for Psychiatry Research, Region Stockholm and Astrid Lindgren Children's Hospital, Karolinska University Hospital, 171 64 Solna, Sweden.
Alves-Lopes JP; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
Bjarnason R; Children's Medical Center, Landspítali University Hospital, 101 Reykjavik, Iceland.; Department of Paediatrics Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.
Romerius P; Department of Paediatric Oncology and Haematology, Clinical Sciences, Lund University, Barn-och Ungdomssjukhuset Lund, Skånes Universitetssjukhus, 221 85 Lund, Sweden.
Sundin M; Division of Paediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 141 52 Huddinge, Sweden.; Pediatric Blood Disorders, Immunodeficiency and Stem Cell Transplantation Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, 141 86 Huddinge, Sweden.
Norén Nyström U; Division of Paediatrics, Department of Clinical Science, Umeå University, 901 87 Umeå, Sweden.
Langenskiöld C; Department of Paediatric Oncology, The Queen Silvia Children's Hospital, 416 50 Gothenburg, Sweden.
Vogt H; Crown Princess Victoria's Child and Youth Hospital, and Department of Biomedical and Clinical Sciences, Linköping University, 581 83 Linköping, Sweden.
Henningsohn L; Division of Urology, Institution for Clinical Science Intervention and Technology, Karolinska Institutet, 141 52 Huddinge, Sweden.
Petersen C; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
Söder O; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
Guo J; Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Mitchell RT; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK.; Edinburgh Royal Hospital for Sick Children, Edinburgh EH9 1LF, UK.
Jahnukainen K; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.; Division of Haematology-Oncology and Stem Cell Transplantation, Children's Hospital, University of Helsinki, Helsinki University Central Hospital, 00029 Helsinki, Finland.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 171 64 Solna, Sweden.
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Źródło:
Cells [Cells] 2021 Jan 27; Vol. 10 (2). Date of Electronic Publication: 2021 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fertility Preservation*
Laminin/*metabolism
Puberty/*metabolism
Spermatogonia/*metabolism
Basement Membrane/metabolism ; Collagen Type IV/metabolism ; Fibronectins/metabolism ; Humans ; Male ; Models, Biological ; Seminiferous Tubules/metabolism ; Spermatozoa/metabolism ; Testis/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer.
Autorzy:
Tharmalingam MD; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.; KK Women's and Children's Hospital, Bukit Timah Rd, 100, Singapore, 229899, Singapore.
Matilionyte G; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.
Wallace WHB; Edinburgh Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh, EH9 1LF, Scotland, UK.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Jahnukainen K; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.; Division of Haematology-Oncology and Stem Cell Transplantation, Children's Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland.
Oliver E; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Goriely A; Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX39DS, UK.
Lane S; Department of Paediatrics and Child Health, Oxford University Hospitals NHS Foundation Trust, and Nuffield Department of Womens and Reproductive Health, University of Oxford, Oxford, UK.
Guo J; Section of Andrology, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Cairns B; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Jorgensen A; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Blegdamsvej 9, 2100, Copenhagen, Denmark.
Allen CM; Biomedical Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.
Lopes F; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.
Anderson RA; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.
Spears N; Biomedical Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.
Mitchell RT; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK. .; Edinburgh Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh, EH9 1LF, Scotland, UK. .
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Źródło:
BMC medicine [BMC Med] 2020 Dec 04; Vol. 18 (1), pp. 374. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji:
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carboplatin/*adverse effects
Cisplatin/*adverse effects
Fertility Preservation/*methods
Neoplasms/*complications
Testis/*drug effects
Animals ; Carboplatin/pharmacology ; Child ; Cisplatin/pharmacology ; Humans ; Male ; Mice ; Neoplasms/drug therapy ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment.
Autorzy:
Hutka M; Medical Research Council (MRC) Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Kadam P; Biology of the Testis, Research Laboratory for Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Van Saen D; Biology of the Testis, Research Laboratory for Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Homer NZM; Edinburgh CRF Mass Spectrometry Core, Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Onofre J; Biology of the Testis, Research Laboratory for Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Wallace WHB; Department of Oncology and Haematology, Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh EH9 1LF, UK.
Smith LB; Medical Research Council (MRC) Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.; School of Environmental and Life Sciences, University of Newcastle, Callaghan, 2308 New South Wales, Australia.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Visionsgatan 4, 171 64 Solna, Sweden.
Goossens E; Biology of the Testis, Research Laboratory for Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Mitchell RT; Medical Research Council (MRC) Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.; Department of Diabetes and Endocrinology, Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh EH9 1LF, UK.
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Źródło:
Cancers [Cancers (Basel)] 2020 Sep 30; Vol. 12 (10). Date of Electronic Publication: 2020 Sep 30.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Rebuilding the human testis in vitro.
Autorzy:
Oliver E; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden.
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Źródło:
Andrology [Andrology] 2020 Jul; Vol. 8 (4), pp. 825-834. Date of Electronic Publication: 2019 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Models, Biological*
Spermatogenesis*
Testis*
Humans ; In Vitro Techniques ; Male
Czasopismo naukowe
Tytuł:
Fertility sparing strategies for pre- and peripubertal male cancer patients.
Autorzy:
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.
Wyns C; Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
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Źródło:
Ecancermedicalscience [Ecancermedicalscience] 2020 Feb 27; Vol. 14, pp. 1016. Date of Electronic Publication: 2020 Feb 27 (Print Publication: 2020).
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Tytuł:
Human Pluripotent Stem Cells in Reproductive Science-a Comparison of Protocols Used to Generate and Define Male Germ Cells from Pluripotent Stem Cells.
Autorzy:
Kurek M; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 17164 Solna, Sweden.
Albalushi H; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 17164 Solna, Sweden.; College of Medicine and Health Sciences, Sultan Qaboos University, Muscat 123, Oman.
Hovatta O; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet and University Hospital Karolinska Institutet, 141 52 Huddinge, Sweden.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, 17164 Solna, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Feb 04; Vol. 21 (3). Date of Electronic Publication: 2020 Feb 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cytological Techniques/*methods
Germ Cells/*cytology
Pluripotent Stem Cells/*cytology
Reproduction/*physiology
Cell Differentiation/physiology ; Embryonic Stem Cells/cytology ; Humans ; Infertility/physiopathology ; Male
Czasopismo naukowe
Tytuł:
Exogenous Gonadotrophin Stimulation Induces Partial Maturation of Human Sertoli Cells in a Testicular Xenotransplantation Model for Fertility Preservation.
Autorzy:
Hutka M; Medical Research Council (MRC) Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
Smith LB; Medical Research Council (MRC) Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.; School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia.
Goossens E; Biology of the Testis, Research Laboratory for Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Wallace WHB; Department of Oncology and Haematology, Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh EH9 1LF, UK.
Stukenborg JB; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Solna SE-17164, Sweden.
Mitchell RT; Medical Research Council (MRC) Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.; Department of Diabetes and Endocrinology, Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh EH9 1LF, UK.
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Źródło:
Journal of clinical medicine [J Clin Med] 2020 Jan 18; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 18.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Laminin 521 Stabilizes the Pluripotency Expression Pattern of Human Embryonic Stem Cells Initially Derived on Feeder Cells.
Autorzy:
Albalushi H; Nordfertil Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.; College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Kurek M; Nordfertil Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
Karlsson L; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
Landreh L; Nordfertil Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
Kjartansdóttir KR; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
Söder O; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
Hovatta O; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
Stukenborg JB; Nordfertil Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital Karolinska Institutet, Stockholm, Sweden.
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Źródło:
Stem cells international [Stem Cells Int] 2018 Feb 18; Vol. 2018, pp. 7127042. Date of Electronic Publication: 2018 Feb 18 (Print Publication: 2018).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells.
Autorzy:
Panula S; Division of Obstetrics and Gynecology, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Huddinge, SE-141 86, Stockholm, Sweden.
Reda A; Pediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76, Stockholm, Sweden.
Stukenborg JB; Pediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76, Stockholm, Sweden.
Ramathal C; Department of Genetics and Department of Obstetrics and Gynecology, Institute for Stem Cell Biology and Regenerative Medicine, Center for Reproductive and Stem Cell Biology, Stanford University, Stanford, CA, 94305, United States of America.
Sukhwani M; Department of Obstetrics, Gynaecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee-Womens Research Institute, Pittsburgh, PA, 15213, United States of America.
Albalushi H; Pediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76, Stockholm, Sweden.; Sultan Qaboos University, College of Medicine and Health Sciences, Muscat, Oman.
Edsgärd D; Department of Cell and Molecular Biology, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
Nakamura M; Center for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Söder O; Pediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76, Stockholm, Sweden.
Orwig KE; Department of Obstetrics, Gynaecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee-Womens Research Institute, Pittsburgh, PA, 15213, United States of America.
Yamanaka S; Center for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.; Gladstone Institute of Cardiovascular Disease, San Francisco, CA, 94158, United States of America.
Reijo Pera RA; Department of Genetics and Department of Obstetrics and Gynecology, Institute for Stem Cell Biology and Regenerative Medicine, Center for Reproductive and Stem Cell Biology, Stanford University, Stanford, CA, 94305, United States of America.; Department of Cell Biology and Neurosciences and Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, United States of America.
Hovatta O; Division of Obstetrics and Gynecology, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Huddinge, SE-141 86, Stockholm, Sweden.
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Źródło:
PloS one [PLoS One] 2016 Oct 21; Vol. 11 (10), pp. e0165268. Date of Electronic Publication: 2016 Oct 21 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Embryonic Stem Cells/*metabolism
RNA-Binding Proteins/*metabolism
Cell Differentiation ; Female ; Gene Expression ; Germ Cells/cytology ; Heterografts ; Humans ; Male ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
A Combination of Culture Conditions and Gene Expression Analysis Can Be Used to Investigate and Predict hES Cell Differentiation Potential towards Male Gonadal Cells.
Autorzy:
Kjartansdóttir KR; Department of Women's and Children's Health, Pediatric Endocrinology Unit, Q2:08, Karolinska Institutet and University Hospital, SE-171 76, Stockholm, Sweden.; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska Institutet, SE-141 86, Huddinge, Sweden.; Laboratory of Reproductive Biology, Scientific Unit, Horsens Hospital, DK-8700, Horsens, Denmark.
Reda A; Department of Women's and Children's Health, Pediatric Endocrinology Unit, Q2:08, Karolinska Institutet and University Hospital, SE-171 76, Stockholm, Sweden.
Panula S; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska Institutet, SE-141 86, Huddinge, Sweden.
Day K; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska Institutet, SE-141 86, Huddinge, Sweden.
Hultenby K; Division of Clinical Research Centre, Department of Laboratory Medicine, Karolinska Institutet, SE-141 86, Huddinge, Sweden.
Söder O; Department of Women's and Children's Health, Pediatric Endocrinology Unit, Q2:08, Karolinska Institutet and University Hospital, SE-171 76, Stockholm, Sweden.
Hovatta O; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska Institutet, SE-141 86, Huddinge, Sweden.
Stukenborg JB; Department of Women's and Children's Health, Pediatric Endocrinology Unit, Q2:08, Karolinska Institutet and University Hospital, SE-171 76, Stockholm, Sweden.
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Źródło:
PloS one [PLoS One] 2015 Dec 02; Vol. 10 (12), pp. e0144029. Date of Electronic Publication: 2015 Dec 02 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
Bone Morphogenetic Protein 7/*physiology
Cell Differentiation/*physiology
Embryonic Stem Cells/*cytology
Testis/*cytology
Cells, Cultured ; Culture Media ; Fibroblast Growth Factor 2/metabolism ; Humans ; Male
Czasopismo naukowe
Tytuł:
The gut microbiota and developmental programming of the testis in mice.
Autorzy:
Al-Asmakh M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Department of Biomedical Science, College of Arts and Sciences, Qatar University, Doha, Qatar.
Stukenborg JB; Department of Women's and Children's Health, Paediatric Endocrinology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden.
Reda A; Department of Women's and Children's Health, Paediatric Endocrinology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden.
Anuar F; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Strand ML; Department of Women's and Children's Health, Paediatric Endocrinology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden.
Hedin L; Sidra Medical and Research Center, Division of Clinical Epidemiology, Doha, Qatar.
Pettersson S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; LKC School of Medicine, Nanyang Technological University, Singapore, Singapore.
Söder O; Department of Women's and Children's Health, Paediatric Endocrinology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden.
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Źródło:
PloS one [PLoS One] 2014 Aug 13; Vol. 9 (8), pp. e103809. Date of Electronic Publication: 2014 Aug 13 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microbiota*
Testis/*growth & development
Animals ; Blood-Testis Barrier/growth & development ; Cell Adhesion ; Fertility ; Male ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Permeability ; Specific Pathogen-Free Organisms
Czasopismo naukowe
Tytuł:
Insulin solubility transitions by pH-dependent interactions with proinsulin C-peptide.
Autorzy:
Landreh M; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.
Alvelius G
Willander H
Stukenborg JB
Söder O
Johansson J
Jörnvall H
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Źródło:
The FEBS journal [FEBS J] 2012 Dec; Vol. 279 (24), pp. 4589-97. Date of Electronic Publication: 2012 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hydrogen-Ion Concentration*
C-Peptide/*chemistry
Insulin/*chemistry
C-Peptide/physiology ; Humans ; Solubility
Czasopismo naukowe
Tytuł:
Differentiation of stem cells upon deprivation of exogenous FGF2: a general approach to study spontaneous differentiation of hESCs in vitro.
Autorzy:
Kjartansdóttir KR; Laboratory of Reproductive Biology, Scientific Unit, Horsens Hospital, Denmark. />Gabrielsen A
Reda A
Söder O
Bergström-Tengzelius R
Andersen CY
Hovatta O
Stukenborg JB
Fedder J
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Źródło:
Systems biology in reproductive medicine [Syst Biol Reprod Med] 2012 Dec; Vol. 58 (6), pp. 330-8. Date of Electronic Publication: 2012 Jun 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation/*drug effects
Embryonic Stem Cells/*drug effects
Fibroblast Growth Factor 2/*pharmacology
DEAD-box RNA Helicases/genetics ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism ; Gene Expression/drug effects ; Homeodomain Proteins/genetics ; Humans ; In Vitro Techniques ; Nanog Homeobox Protein ; Octamer Transcription Factor-3/genetics ; RNA-Binding Proteins/genetics ; Tretinoin/pharmacology
Czasopismo naukowe
Tytuł:
The future of testis research is turning 6! Six years of international network for young researchers in male fertility.
Autorzy:
Tüttelmann F; Institute of Human Genetics, University of Münster, Münster, Germany Laboratory of Experimental Medicine and Endocrinology, Catholic University of Leuven, Leuven, Belgium. />De Gendt K
Amaral A
Giachini C C
Welsh M
Blomberg Jensen M
Nurmio M
Wahlgren A
Stukenborg JB
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Źródło:
International journal of andrology [Int J Androl] 2012 Apr; Vol. 35 (2), pp. 211-3. Date of Electronic Publication: 2012 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Biomedical Research*
Fertility*
Societies, Scientific*
Testis*
Education ; Humans ; Infertility, Male ; International Cooperation ; Male ; Research Personnel
Czasopismo naukowe
Tytuł:
Ontogenesis of Ap-2γ expression in rat testes.
Autorzy:
Hou M; Department of Women's and Children's Health, Astrid Lindgren Children's Hospital, Pediatric Endocrinology Unit, Q2:08, Stockholm, Sweden. Mi.Hou @ ki.se
Stukenborg JB
Nurmio M
Andersson M
Toppari J
Söder O
Jahnukainen K
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Źródło:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation [Sex Dev] 2011; Vol. 5 (4), pp. 188-96. Date of Electronic Publication: 2011 Jun 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Testis/*chemistry
Testis/*growth & development
Transcription Factor AP-2/*analysis
Animals ; Antigens, CD/analysis ; Biomarkers/analysis ; Cell Differentiation ; Cell Nucleus/chemistry ; Flow Cytometry ; Immunohistochemistry ; Male ; Membrane Glycoproteins/analysis ; Rats ; Rats, Sprague-Dawley ; Spermatocytes/chemistry ; Spermatogonia/chemistry ; Testis/embryology ; Tetraspanin 29 ; Thy-1 Antigens/analysis
Czasopismo naukowe
Tytuł:
Ontogenesis of testis development and function in humans.
Autorzy:
Stukenborg JB; Paediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital, Stockholm, Sweden.
Colón E
Söder O
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Źródło:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation [Sex Dev] 2010 Sep; Vol. 4 (4-5), pp. 199-212. Date of Electronic Publication: 2010 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Organogenesis*
Testis/*embryology
Cell Lineage ; Humans ; Male ; Puberty/physiology ; Spermatogenesis/physiology ; Spermatozoa/cytology ; Testis/physiology
Czasopismo naukowe
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