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    Tytuł:
    Elbasvir/grazoprevir for hepatitis C virus genotype 1b East-Asian patients receiving hemodialysis.
    Autorzy:
    Liu CH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Peng CY; School of Medicine, China Medical University, Taichung, Taiwan.; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
    Fang YJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Kao WY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Yang SS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taipei, Taiwan.; Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan.; Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan.
    Lin CK; Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
    Lai HC; School of Medicine, China Medical University, Taichung, Taiwan.; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
    Su WP; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
    Fang SU; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Chang CC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Su TH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Liu CJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Chen PJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
    Kao JH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. .; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan. .; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Jun 08; Vol. 10 (1), pp. 9180. Date of Electronic Publication: 2020 Jun 08.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Amides/*therapeutic use
    Antiviral Agents/*therapeutic use
    Benzofurans/*therapeutic use
    Carbamates/*therapeutic use
    Cyclopropanes/*therapeutic use
    Hepacivirus/*drug effects
    Hepatitis C, Chronic/*drug therapy
    Imidazoles/*therapeutic use
    Quinoxalines/*therapeutic use
    Sulfonamides/*therapeutic use
    Asian People ; Drug Resistance, Viral/drug effects ; Drug Therapy, Combination/methods ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Renal Dialysis/adverse effects ; Sustained Virologic Response
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Glecaprevir/pibrentasvir for patients with chronic hepatitis C virus infection and severe renal impairment.
    Autorzy:
    Liu CH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Yang SS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taipei, Taiwan.; Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan.; Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan.
    Peng CY; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.
    Lin WT; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
    Liu CJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Tseng TC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Chen PJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
    Kao JH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
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    Źródło:
    Journal of viral hepatitis [J Viral Hepat] 2020 Jun; Vol. 27 (6), pp. 568-575. Date of Electronic Publication: 2020 Feb 06.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Hepatitis C, Chronic*/drug therapy
    Aminoisobutyric Acids/*therapeutic use
    Antiviral Agents/*therapeutic use
    Benzimidazoles/*therapeutic use
    Cyclopropanes/*therapeutic use
    Lactams, Macrocyclic/*therapeutic use
    Leucine/*analogs & derivatives
    Proline/*analogs & derivatives
    Pyrrolidines/*therapeutic use
    Quinoxalines/*therapeutic use
    Renal Insufficiency, Chronic/*complications
    Sulfonamides/*therapeutic use
    Genotype ; Hepacivirus ; Humans ; Leucine/therapeutic use ; Proline/therapeutic use ; Retrospective Studies ; Sustained Virologic Response ; Taiwan
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Early antiviral therapy reduces the risk of lymphoma in patients with chronic hepatitis C infection.
    Autorzy:
    Su TH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Liu CJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Tseng TC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Chou SW; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Liu CH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Yang HC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Wu SJ; Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Chen PJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.
    Chen DS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
    Chen CL; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Kao JH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.
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    Źródło:
    Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2019 Feb; Vol. 49 (3), pp. 331-339. Date of Electronic Publication: 2018 Dec 27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*administration & dosage
    Hepatitis C, Chronic/*drug therapy
    Lymphoma/*prevention & control
    Adult ; Antiviral Agents/therapeutic use ; Cohort Studies ; Drug Therapy, Combination ; Female ; Humans ; Incidence ; Interferon-alpha/therapeutic use ; Lymphoma/epidemiology ; Male ; Middle Aged ; Polyethylene Glycols/chemistry ; Ribavirin/therapeutic use ; Taiwan
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Real-world effectiveness and safety of sofosbuvir and ledipasvir with or without ribavirin for patients with hepatitis C virus genotype 1 infection in Taiwan.
    Autorzy:
    Liu CH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Liu CJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Yang HC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan.
    Hong CM; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Tseng TC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Chen PJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
    Kao JH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
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    Źródło:
    PloS one [PLoS One] 2018 Dec 21; Vol. 13 (12), pp. e0209299. Date of Electronic Publication: 2018 Dec 21 (Print Publication: 2018).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antiviral Agents/*administration & dosage
    Benzimidazoles/*administration & dosage
    Fluorenes/*administration & dosage
    Hepacivirus/*genetics
    Hepatitis C, Chronic/*drug therapy
    Hepatitis C, Chronic/*virology
    Ribavirin/*administration & dosage
    Uridine Monophosphate/*analogs & derivatives
    Adult ; Aged ; Aged, 80 and over ; Antiviral Agents/adverse effects ; Benzimidazoles/adverse effects ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Fluorenes/adverse effects ; Genotype ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Ribavirin/adverse effects ; Safety ; Sofosbuvir ; Sustained Virologic Response ; Taiwan ; Treatment Outcome ; Uridine Monophosphate/administration & dosage ; Uridine Monophosphate/adverse effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Generic sofosbuvir-based interferon-free direct acting antiviral agents for patients with chronic hepatitis C virus infection: a real-world multicenter observational study.
    Autorzy:
    Liu CH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Huang YJ; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Taichung Veterans General Hospital, Taichung, Taiwan.
    Yang SS; Liver Center, Cathay General Hospital Medical Center, Taipei, Taiwan.; School of Medicine, Fu-Jen Catholic University College of Medicine, Taipei, Taiwan.
    Chang CH; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Taichung Veterans General Hospital, Taichung, Taiwan.
    Yang SS; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan.
    Sun HY; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Liu CJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Liu WC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Yang HC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan.
    Hong CM; Department of Traumatology, National Taiwan University Hospital, Taipei, Taiwan.
    Tseng TC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Chen PJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
    Hung CC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
    Kao JH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. .; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan. .; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan. .
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    Źródło:
    Scientific reports [Sci Rep] 2018 Sep 12; Vol. 8 (1), pp. 13699. Date of Electronic Publication: 2018 Sep 12.
    Typ publikacji:
    Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Hepacivirus/*drug effects
    Hepatitis C, Chronic/*drug therapy
    Interferons/*therapeutic use
    Sofosbuvir/*therapeutic use
    Adult ; Aged ; Aged, 80 and over ; Drug Therapy, Combination/methods ; Female ; Hepatitis C, Chronic/virology ; Humans ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/virology ; Male ; Middle Aged ; Retrospective Studies ; Ribavirin/therapeutic use ; Taiwan
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Generic velpatasvir plus sofosbuvir for hepatitis C virus infection in patients with or without human immunodeficiency virus coinfection.
    Autorzy:
    Liu CH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Douliou, Taiwan.
    Sun HY; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Liu CJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Sheng WH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Hsieh SM; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Lo YC; Centers for Disease Control, Taipei, Taiwan.
    Liu WC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Yang HC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Department of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan.
    Hong CM; Department of Traumatology, National Taiwan University Hospital, Taipei, Taiwan.
    Tseng TC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Chen PJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Genomics Research, Center, Academia Sinica, Taipei, Taiwan.
    Hung CC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
    Kao JH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
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    Źródło:
    Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2018 Jun; Vol. 47 (12), pp. 1690-1698. Date of Electronic Publication: 2018 Apr 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*administration & dosage
    Carbamates/*administration & dosage
    Hepatitis C/*drug therapy
    Heterocyclic Compounds, 4 or More Rings/*administration & dosage
    Sofosbuvir/*administration & dosage
    Adult ; Aged ; Antiviral Agents/therapeutic use ; Coinfection ; Drug Combinations ; Female ; HIV Infections/drug therapy ; Hepacivirus/isolation & purification ; Humans ; Male ; Middle Aged ; Ribavirin/therapeutic use ; Sustained Virologic Response ; Taiwan ; Tenofovir/therapeutic use ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Combination Therapy for Chronic Hepatitis B: Current Updates and Perspectives.
    Autorzy:
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Liu CJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
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    Źródło:
    Gut and liver [Gut Liver] 2017 Sep 15; Vol. 11 (5), pp. 590-603.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Antiviral Agents/*administration & dosage
    Hepatitis B, Chronic/*drug therapy
    Interferon-alpha/*administration & dosage
    Nucleic Acid Synthesis Inhibitors/*administration & dosage
    Adenine/administration & dosage ; Adenine/analogs & derivatives ; Drug Therapy, Combination ; Humans ; Lamivudine/administration & dosage ; Organophosphonates/administration & dosage ; Telbivudine ; Tenofovir/administration & dosage ; Thymidine/administration & dosage ; Thymidine/analogs & derivatives ; Treatment Outcome ; Viral Load/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    High Serum Lipopolysaccharide-Binding Protein Level in Chronic Hepatitis C Viral Infection Is Reduced by Anti-Viral Treatments.
    Autorzy:
    Nien HC; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Liver Disease Prevention and Treatment Research Foundation, Taipei, Taiwan.; Department of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Hsu SJ; Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan.
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Yang PJ; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
    Sheu JC; Liver Disease Prevention and Treatment Research Foundation, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Wang JT; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
    Chow LP; Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.
    Chen CL; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
    Kao JH; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
    Yang WS; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
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    Źródło:
    PloS one [PLoS One] 2017 Jan 20; Vol. 12 (1), pp. e0170028. Date of Electronic Publication: 2017 Jan 20 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Carrier Proteins/*blood
    Hepatitis C, Chronic/*blood
    Membrane Glycoproteins/*blood
    Acute-Phase Proteins ; Adult ; Biomarkers/blood ; Case-Control Studies ; Female ; Hepatitis C, Chronic/drug therapy ; Humans ; Male ; Middle Aged ; Retrospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Four-year entecavir therapy reduces hepatocellular carcinoma, cirrhotic events and mortality in chronic hepatitis B patients.
    Autorzy:
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Hu TH; Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
    Chen CY; Department of Internal Medicine, Chia-Yi Christian Hospital, Chiayi, Taiwan.
    Huang YH; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
    Chuang WL; Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
    Lin CC; Division of Gastroenterology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
    Wang CC; Division of Gastroenterology, Department of Internal Medicine, Taipei Tzuchi Hospital, the Buddhist Tzuchi Medical Foundation, Taipei, Taiwan.
    Su WW; Department of Gastroenterology and Hepatology, Changhua Christian Hospital, Changhua, Taiwan.
    Chen MY; Department of Internal Medicine, Shuang-Ho Hospital, Taipei Medical University, Taipei, Taiwan.
    Peng CY; Division of Hepatogastroenterology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
    Chien RN; Liver Research Unit, Chang Gung Memorial Hospital, Keelung, Taiwan.
    Huang YW; Liver Center, Cathay General Hospital Medical Center, Taipei, Taiwan.
    Wang HY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
    Lin CL; Department of Gastroenterology, Ren-Ai Branch, Taipei City Hospital, Taipei, Taiwan.
    Yang SS; Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
    Chen TM; Division of Hepato-Gastroenterology, Department of Internal Medicine and Department of Medical Research, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.
    Mo LR; Department of Internal Medicine, Tainan Municipal Hospital, Tainan, Taiwan.
    Hsu SJ; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Yunlin, Taiwan.
    Tseng KC; Department of Hepatology, Buddhist Tzu Chi General Hospital, Da-Lin Branch, Chiayi, Taiwan.
    Hsieh TY; Department of Gastroenterology, Tri-service General Hospital, Taipei, Taiwan.
    Suk FM; Division of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
    Hu CT; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Buddhist Tzu Chi General Hospital and University, Hualien, Taiwan.
    Bair MJ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mackay Memorial Hospital, Taitung, Taiwan.
    Liang CC; Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
    Lei YC; Department of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan.
    Tseng TC; Department of Internal Medicine, National Taiwan University Hospital, Jin-Shan Branch, New Taipei City, Taiwan.
    Chen CL; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Kao JH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
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    Corporate Authors:
    C-TEAM study group and the Taiwan Liver Diseases Consortium
    Źródło:
    Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2016 Dec; Vol. 36 (12), pp. 1755-1764. Date of Electronic Publication: 2016 Oct 04.
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Carcinoma, Hepatocellular/*epidemiology
    Guanine/*analogs & derivatives
    Hepatitis B, Chronic/*complications
    Hepatitis B, Chronic/*drug therapy
    Liver Cirrhosis/*mortality
    Liver Neoplasms/*epidemiology
    Adult ; Esophageal and Gastric Varices/epidemiology ; Female ; Gastrointestinal Hemorrhage/epidemiology ; Guanine/therapeutic use ; Hepatitis B e Antigens/blood ; Hepatitis B virus/genetics ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Proportional Hazards Models ; Prospective Studies ; Retrospective Studies ; Taiwan ; Treatment Outcome ; alpha-Fetoproteins/analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Peginterferon alfa-2a plus Weight-Based or Flat-Dose Ribavirin for Treatment-Naïve Hepatitis C Virus Genotype 2 Rapid Responders: A Randomized Trial.
    Autorzy:
    Liu CH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Huang CF; Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Occupational Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
    Liu CJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Dai CY; Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Huang JF; Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Lin JW; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Liang CC; Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
    Yang SS; Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
    Lin CL; Department of Gastroenterology, Taipei City Hospital, Ren-Ai Branch, Taipei, Taiwan.
    Su TH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Yang HC; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Microbiology, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei.
    Chen PJ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taiwan.
    Chuang WL; Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Kao JH; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Yu ML; Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Pokaż więcej
    Źródło:
    Scientific reports [Sci Rep] 2015 Oct 15; Vol. 5, pp. 15255. Date of Electronic Publication: 2015 Oct 15.
    Typ publikacji:
    Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Hepacivirus/*genetics
    Hepatitis C, Chronic/*drug therapy
    Interferon-alpha/*therapeutic use
    Polyethylene Glycols/*therapeutic use
    Ribavirin/*therapeutic use
    Adult ; Aged ; Body Weight ; Dose-Response Relationship, Drug ; Female ; Genotype ; Hepatitis C, Chronic/virology ; Humans ; Male ; Middle Aged ; RNA, Viral/analysis ; RNA, Viral/metabolism ; Recombinant Proteins/therapeutic use ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Peginterferon plus weight-based ribavirin for treatment-naïve hepatitis C virus genotype 2 patients not achieving rapid virologic response: a randomized trial.
    Autorzy:
    Liu CH; 1] Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan [2] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [3] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan [4] Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Huang CF; 1] Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan [2] Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan [3] Department of Occupational Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
    Liu CJ; 1] Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan [2] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [3] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Dai CY; 1] Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan [2] Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
    Huang JF; 1] Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan [2] Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
    Lin JW; Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.
    Liang CC; Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan.
    Yang SS; Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
    Lin CL; Department of Gastroenterology, Taipei City Hospital, Ren-Ai Branch, Taipei, Taiwan.
    Su TH; 1] Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan [2] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [3] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Yang HC; 1] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [2] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan [3] Department of Microbiology, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei.
    Chen PJ; 1] Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan [2] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [3] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Chen DS; 1] Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan [2] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [3] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan [4] Genomics Research Center, Academia Sinica, Taiwan.
    Chuang WL; 1] Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan [2] Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
    Kao JH; 1] Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan [2] Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan [3] Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Yu ML; 1] Institute of Clinical Medicine and Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan [2] Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan [3] Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Pokaż więcej
    Źródło:
    Scientific reports [Sci Rep] 2015 Jul 01; Vol. 5, pp. 11710. Date of Electronic Publication: 2015 Jul 01.
    Typ publikacji:
    Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Hepacivirus/*genetics
    Hepatitis C, Chronic/*drug therapy
    Interferon-alpha/*therapeutic use
    Polyethylene Glycols/*therapeutic use
    Ribavirin/*therapeutic use
    Adult ; Aged ; Drug Administration Schedule ; Female ; Genotype ; Hepatitis C, Chronic/genetics ; Hepatitis C, Chronic/pathology ; Humans ; Interferons ; Interleukins/genetics ; Interleukins/metabolism ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; RNA, Viral/analysis ; RNA, Viral/genetics ; Recombinant Proteins/therapeutic use ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Clinical and virological features of occult hepatitis B in patients with HBsAg seroclearance post-treatment or spontaneously.
    Autorzy:
    Cheng HR; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
    Kao JH
    Wu HL
    Chen TC
    Tseng TC
    Liu CH
    Su TH
    Chen PJ
    Chen DS
    Liu CJ
    Pokaż więcej
    Źródło:
    Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2014 Jul; Vol. 34 (6), pp. e71-9. Date of Electronic Publication: 2013 Oct 02.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*therapeutic use
    Hepatitis B Surface Antigens/*blood
    Hepatitis B virus/*drug effects
    Hepatitis B, Chronic/*drug therapy
    Interferon-alpha/*therapeutic use
    Polyethylene Glycols/*therapeutic use
    Ribavirin/*therapeutic use
    Adult ; Biomarkers/blood ; Cell Line ; Cross-Sectional Studies ; DNA, Viral/blood ; Drug Therapy, Combination ; Female ; Genotype ; Hepatitis B virus/genetics ; Hepatitis B virus/immunology ; Hepatitis B, Chronic/blood ; Hepatitis B, Chronic/diagnosis ; Hepatitis B, Chronic/epidemiology ; Humans ; Male ; Middle Aged ; Mutation ; Phenotype ; Prevalence ; Promoter Regions, Genetic ; Recombinant Proteins/therapeutic use ; Taiwan/epidemiology ; Time Factors ; Transfection ; Treatment Outcome ; Viral Envelope Proteins/genetics ; Viral Load
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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