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Wyszukujesz frazę ""Sulfhydryl Compounds"" wg kryterium: Temat


Tytuł:
A thiol-ene mediated approach for peptide bioconjugation using 'green' solvents under continuous flow.
Autorzy:
Rabadán González I; Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland. .
McLean JT; Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland. .
Ostrovitsa N; Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland. .
Fitzgerald S; Department of Chemistry, RCSI, 123 St Stephen's Green, Dublin 2, Ireland.
Mezzetta A; University of Pisa, Via Bonanno 33, 56126, Pisa, Italy.
Guazzelli L; University of Pisa, Via Bonanno 33, 56126, Pisa, Italy.
O'Shea DF; Department of Chemistry, RCSI, 123 St Stephen's Green, Dublin 2, Ireland.
Scanlan EM; Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland. .
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2024 Mar 13; Vol. 22 (11), pp. 2203-2210. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfhydryl Compounds*
Peptides*
Solvents ; Water
Czasopismo naukowe
Tytuł:
Rhodobacteraceae methanethiol oxidases catalyze methanethiol degradation to produce sulfane sulfur other than hydrogen sulfide.
Autorzy:
Cao Q; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Liu X; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Wang Q; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Liu Z; Qingdao Institute of Animal Husbandry and Veterinary Medicine, Qingdao, China.
Xia Y; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Xun L; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.; School of Molecular Biosciences, Washington State University, Pullman, Washington, USA.
Liu H; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
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Źródło:
MBio [mBio] 2024 Mar 13; Vol. 15 (3), pp. e0290723. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Hydrogen Sulfide*
Rhodobacteraceae*/metabolism
Sulfhydryl Compounds*
Sulfonium Compounds*
Cysteine ; Hydrogen Peroxide ; Sulfur/metabolism ; Sulfur Compounds ; Oxidoreductases/metabolism
Czasopismo naukowe
Tytuł:
Detection and discrimination of glutathione among biological thiols based on oxalyl dihydrazide decorated sulfur nanodots.
Autorzy:
Xing Y; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Analytical Science and Technology of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Materials Science, Hebei University, Baoding 071002, P. R. China. .
Zhu S; Sanitary Inspection Department of Zibo Center for Disease Control and Prevention, Zibo, Shandong 255026, China.
Li J; College of Pharmaceutical Science, Hebei University, Baoding, 071002, P. R. China.
Li W; College of Pharmaceutical Science, Hebei University, Baoding, 071002, P. R. China.
Wang Z; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Analytical Science and Technology of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Materials Science, Hebei University, Baoding 071002, P. R. China. .
Shi YE; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Analytical Science and Technology of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Materials Science, Hebei University, Baoding 071002, P. R. China. .
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Źródło:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Mar 05; Vol. 60 (20), pp. 2760-2763. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfhydryl Compounds*
Fluorescent Dyes*/chemistry
Glutathione ; Sulfur ; Fluorescence
Czasopismo naukowe
Tytuł:
Exploring the mechanism of interaction between TBG and halogenated thiophenols: Insights from fluorescence analysis and molecular simulation.
Autorzy:
Chen Y; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Liang W; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Huang M; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Li C; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Song Z; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Zheng Y; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.
Yi Z; College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2024 Mar; Vol. 261 (Pt 2), pp. 129645. Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Thyroxine-Binding Globulin*/metabolism
Thyroxine*/pharmacology
Phenols*
Sulfhydryl Compounds*
Humans ; Thyroxine-Binding Proteins/metabolism ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Rapid, traceless and facile peptide cyclization enabled by tetrazine-thiol exchange.
Autorzy:
Geers DWT; Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.
Gavriel K; Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.
Neumann K; Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands.
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Źródło:
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2024 Mar; Vol. 30 (3), pp. e3548. Date of Electronic Publication: 2023 Oct 01.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfhydryl Compounds*
Heterocyclic Compounds*
Cyclization ; Peptides/chemistry ; Peptides, Cyclic/chemistry ; Sulfides
Czasopismo naukowe
Tytuł:
Risk factors for malignancy and serious infection in patients with inflammatory bowel disease: a retrospective analysis.
Autorzy:
Tassone D; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Basnayake C; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Wright E; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Lust M; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Kamm MA; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Niewiadomski O; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Schulberg J; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Flanagan E; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Samyue T; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Fry S; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Malcolm R; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Stanley A; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Thompson AJ; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Connell WR; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Ding NS; Department of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
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Źródło:
Internal medicine journal [Intern Med J] 2024 Mar; Vol. 54 (3), pp. 446-454. Date of Electronic Publication: 2023 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammatory Bowel Diseases*/drug therapy
Neoplasms*/epidemiology
Colitis, Ulcerative*/epidemiology
Crohn Disease*/drug therapy
Purines*
Sulfhydryl Compounds*
Humans ; Retrospective Studies ; Tumor Necrosis Factor Inhibitors ; Risk Factors
Czasopismo naukowe
Tytuł:
Remodeling of Mitochondrial Metabolism by a Mitochondria-Targeted RNAi Nanoplatform for Effective Cancer Therapy.
Autorzy:
Xu R; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Guangzhou Key Laboratory of Medical Nanomaterials, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
Huang L; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Guangzhou Key Laboratory of Medical Nanomaterials, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
Liu J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Guangzhou Key Laboratory of Medical Nanomaterials, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
Zhang Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Guangzhou Key Laboratory of Medical Nanomaterials, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
Xu Y; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Guangzhou Key Laboratory of Medical Nanomaterials, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
Li R; The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421001, P. R. China.
Su S; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
Xu X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Guangzhou Key Laboratory of Medical Nanomaterials, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, P. R. China.; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, 528200, P. R. China.
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Źródło:
Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Mar; Vol. 20 (10), pp. e2305923. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Nanoparticles*/chemistry
Propionates*
Sulfhydryl Compounds*
Humans ; Female ; RNA Interference ; RNA, Small Interfering/genetics ; Peptides/metabolism ; Mitochondria/metabolism ; DNA, Mitochondrial ; Adenosine Triphosphate ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology.
Autorzy:
Zeisel L; Department of Pharmacy, LMU Munich, Butenandtstr. 5-13, Munich 81377, Germany.
Felber JG; Department of Pharmacy, LMU Munich, Butenandtstr. 5-13, Munich 81377, Germany.
Scholzen KC; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.
Schmitt C; Department of Pharmacy, LMU Munich, Butenandtstr. 5-13, Munich 81377, Germany.
Wiegand AJ; Department of Pharmacy, LMU Munich, Butenandtstr. 5-13, Munich 81377, Germany.
Komissarov L; Center for Molecular Modeling (CMM), Ghent University, Technologiepark-Zwijnaarde 46, Ghent 9052, Belgium.
Arnér ESJ; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.; Department of Selenoprotein Research, National Institute of Oncology, Budapest 1122, Hungary.
Thorn-Seshold O; Department of Pharmacy, LMU Munich, Butenandtstr. 5-13, Munich 81377, Germany.
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Źródło:
Journal of the American Chemical Society [J Am Chem Soc] 2024 Feb 28; Vol. 146 (8), pp. 5204-5214. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Disulfides*/chemistry
Sulfhydryl Compounds*/chemistry
Cross-Linking Reagents ; Piperazine ; Thioredoxins/metabolism ; Oxidation-Reduction ; Biology
Czasopismo naukowe
Tytuł:
Ageing-dependent thiol oxidation reveals early oxidation of proteins with core proteostasis functions.
Autorzy:
Jonak K; https://ror.org/034tvp782 Laboratory of Molecular Basis of Aging and Rejuvenation, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Suppanz I; CIBSS Centre for Integrative Biological Signalling Research, University of Freiburg, Freiburg, Germany.
Bender J; https://ror.org/00fbnyb24 Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Chacinska A; IMol Polish Academy of Sciences, Warsaw, Poland.
Warscheid B; CIBSS Centre for Integrative Biological Signalling Research, University of Freiburg, Freiburg, Germany.; https://ror.org/00fbnyb24 Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany.
Topf U; https://ror.org/034tvp782 Laboratory of Molecular Basis of Aging and Rejuvenation, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland .
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Źródło:
Life science alliance [Life Sci Alliance] 2024 Feb 21; Vol. 7 (5). Date of Electronic Publication: 2024 Feb 21 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Sulfhydryl Compounds*/metabolism
Proteostasis*
Mice ; Animals ; Oxidation-Reduction ; Saccharomyces cerevisiae/metabolism ; Aging ; Proteome/metabolism
Czasopismo naukowe
Tytuł:
The Thiol Group Reactivity and the Antioxidant Property of Human Serum Albumin Are Controlled by the Joint Action of Fatty Acids and Glucose Binding.
Autorzy:
Uzelac T; Department of Biochemistry and Centre of Excellence for Molecular and Food Sciences, University of Belgrade-Faculty of Chemistry (UBFC), Studentski trg 12-16, 11158 Belgrade, Serbia.
Smiljanić K; Department of Biochemistry and Centre of Excellence for Molecular and Food Sciences, University of Belgrade-Faculty of Chemistry (UBFC), Studentski trg 12-16, 11158 Belgrade, Serbia.
Takić M; Centre of Research Excellence in Nutrition and Metabolism, Group for Nutrition and Metabolism, National Institute of Republic of Serbia, Institute for Medical Research, University of Belgrade, Tadeuša Košćuškog 1, 11000 Belgrade, Serbia.
Šarac I; Centre of Research Excellence in Nutrition and Metabolism, Group for Nutrition and Metabolism, National Institute of Republic of Serbia, Institute for Medical Research, University of Belgrade, Tadeuša Košćuškog 1, 11000 Belgrade, Serbia.
Oggiano G; Centre of Research Excellence in Nutrition and Metabolism, Group for Nutrition and Metabolism, National Institute of Republic of Serbia, Institute for Medical Research, University of Belgrade, Tadeuša Košćuškog 1, 11000 Belgrade, Serbia.
Nikolić M; Department of Biochemistry and Centre of Excellence for Molecular and Food Sciences, University of Belgrade-Faculty of Chemistry (UBFC), Studentski trg 12-16, 11158 Belgrade, Serbia.
Jovanović V; Department of Biochemistry and Centre of Excellence for Molecular and Food Sciences, University of Belgrade-Faculty of Chemistry (UBFC), Studentski trg 12-16, 11158 Belgrade, Serbia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 16; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Serum Albumin, Human*/metabolism
Sulfhydryl Compounds*/chemistry
Humans ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Fatty Acids/metabolism ; Serum Albumin/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł:
Measurement of the intracellular active metabolites of thiopurine drugs to evaluate the enzymatic activity of nudix hydrolase 15 in human blood samples.
Autorzy:
Okamoto H; Laboratory of Biochemistry, Graduate School of Pharmaceutical Sciences, Japan; Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
Tanaka Y; Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan; Division of Medicinal Safety Science, National Institute of Health Sciences, Kanagawa, Japan. Electronic address: .
Shibagaki Y; Laboratory of Biochemistry, Graduate School of Pharmaceutical Sciences, Japan.
Kuronuma S; Biomedical Laboratory, Department of Research, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Miyatani Y; Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan; Department of Gastroenterology and Hepatology, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Umeda S; Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan; Department of Gastroenterology and Hepatology, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Mishiro-Sato E; Laboratory of Biochemistry, Graduate School of Pharmaceutical Sciences, Japan.
Takeuchi O; Biomedical Laboratory, Department of Research, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Hattori S; Laboratory of Biochemistry, Graduate School of Pharmaceutical Sciences, Japan.
Kobayashi T; Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan; Department of Gastroenterology and Hepatology, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Okuwaki M; Laboratory of Biochemistry, Graduate School of Pharmaceutical Sciences, Japan. Electronic address: .
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Źródło:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2024 Feb 15; Vol. 1234, pp. 123993. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Nudix Hydrolases*
Leukocytes, Mononuclear*/metabolism
Purines*
Sulfhydryl Compounds*
Humans ; Chromatography, Liquid ; Cell Extracts ; Reproducibility of Results ; Pyrophosphatases/genetics ; Pyrophosphatases/chemistry ; Pyrophosphatases/metabolism ; Tandem Mass Spectrometry ; Guanosine Triphosphate ; Mercaptopurine
Czasopismo naukowe
Tytuł:
Phenylpropynones as Selective Disulfide Rebridging Bioconjugation Reagents.
Autorzy:
Maes D; Ghent University, Department of Organic and Macromolecular Chemistry, Organic Synthesis Group, Krijgslaan 281 (S4), 9000 Ghent, Belgium.
Nicque M; Ghent University, Department of Organic and Macromolecular Chemistry, Organic Synthesis Group, Krijgslaan 281 (S4), 9000 Ghent, Belgium.
Iftikhar M; Ghent University, Department of Organic and Macromolecular Chemistry, Organic Synthesis Group, Krijgslaan 281 (S4), 9000 Ghent, Belgium.
Winne JM; Ghent University, Department of Organic and Macromolecular Chemistry, Organic Synthesis Group, Krijgslaan 281 (S4), 9000 Ghent, Belgium.
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Źródło:
Organic letters [Org Lett] 2024 Feb 02; Vol. 26 (4), pp. 895-899. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disulfides*
Sulfhydryl Compounds*
Cross-Linking Reagents ; Indicators and Reagents ; Propionates/chemistry
Czasopismo naukowe
Tytuł:
Uphill battle: Innovation of thiopurine therapy in global inflammatory bowel disease care.
Autorzy:
Bayoumy AB; Department of Internal Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Mulder CJJ; Department of Gastroenterology and Hepatology, AGEM Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
Ansari AR; Department of Gastroenterology and Hepatology, London Bridge Hospital, London, UK.
Barclay ML; Department of Gastroenterology, Christchurch Hospital, Christchurch, Waitaha - Canterbury, New Zealand.; Department of Clinical Pharmacology, Christchurch Hospital, Christchurch, Waitaha - Canterbury, New Zealand.
Florin T; Mater Research, University of Queensland, Translational Research Institute, South Brisbane, Australia.
Kiszka-Kanowitz M; Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Copenhagen University Hospital - Amager and Hvidovre Hospital, Hvidovre, Denmark.
Derijks L; Department of Clinical Pharmacy, Máxima Medical Center, Veldhoven, The Netherlands.; Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center, Maastricht, The Netherlands.
Sharma V; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India.
de Boer NKH; Department of Gastroenterology and Hepatology, AGEM Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
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Źródło:
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology [Indian J Gastroenterol] 2024 Feb; Vol. 43 (1), pp. 36-47. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Inflammatory Bowel Diseases*/drug therapy
Crohn Disease*/drug therapy
Colitis, Ulcerative*/drug therapy
Purines*
Sulfhydryl Compounds*
Humans ; Mercaptopurine ; Azathioprine/therapeutic use ; Immunosuppressive Agents/adverse effects
Czasopismo naukowe
Tytuł:
Apolipoprotein E isoforms and their Cys-thiol modifications impact LRP1-mediated metabolism of triglyceride-rich lipoproteins.
Autorzy:
Matsuura H; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.
Akahane S; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.
Kaido T; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan.
Kamijo T; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan.
Sakamoto K; Department of Laboratory Medicine, University of Yamanashi Hospital, Japan.
Yamauchi K; Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.; Department of Biomedical Laboratory Sciences, School of Health Sciences, Shinshu University, Matsumoto, Japan.
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Źródło:
FEBS letters [FEBS Lett] 2024 Feb; Vol. 598 (3), pp. 347-362. Date of Electronic Publication: 2024 Jan 27.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfhydryl Compounds*
Apolipoproteins E*/metabolism
Apolipoprotein E2/metabolism ; Apolipoprotein E3/genetics ; Apolipoprotein E3/metabolism ; Apolipoprotein E4/genetics ; Apolipoprotein E4/metabolism ; Triglycerides/metabolism ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Carrier Proteins
Czasopismo naukowe
Tytuł:
Thiopurines exert harmful effects on spermatogenesis in Nudt15 knock-in mice.
Autorzy:
Yokota Y; Department of Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Imai T; Department of Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Kawahara M; Department of Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Inatomi O; Department of Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Nishida A; Department of Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Kakuta Y; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, 980-8575, Japan.
Masamune A; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, 980-8575, Japan.
Andoh A; Department of Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan. .
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Źródło:
Journal of gastroenterology [J Gastroenterol] 2024 Feb; Vol. 59 (2), pp. 109-118. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Pyrophosphatases*/genetics
Semen*
Purines*
Sulfhydryl Compounds*
Male ; Mice ; Animals ; Mercaptopurine ; Spermatogenesis
Czasopismo naukowe
Tytuł:
Asymmetric Block Extension of Star-Shaped [PEG-SH] 4 - toward Poly(dehydroalanine)-Functionalized PEG Hydrogels for Catch and Release of Charged Guest Molecules.
Autorzy:
Kowalczuk K; Institute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Lessingstraße 8, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.; Center for Energy and Environmental Chemistry (CEEC), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, Grüne Aue, 07754, Jena, Germany.
Mons PJ; Institute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Lessingstraße 8, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.; Center for Energy and Environmental Chemistry (CEEC), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.
Ulrich HF; Institute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Lessingstraße 8, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.
Wegner VD; Institute of Biochemistry II, Jena University Hospital, Kastanienallee 1, 07747, Jena, Germany.
Brendel JC; Institute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Lessingstraße 8, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.
Mosig AS; Institute of Biochemistry II, Jena University Hospital, Kastanienallee 1, 07747, Jena, Germany.; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany.
Schacher FH; Institute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Lessingstraße 8, 07743, Jena, Germany.; Jena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.; Center for Energy and Environmental Chemistry (CEEC), Friedrich-Schiller-University Jena, Philosophenweg 7, 07743, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, Grüne Aue, 07754, Jena, Germany.
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Źródło:
Macromolecular bioscience [Macromol Biosci] 2024 Feb; Vol. 24 (2), pp. e2300230. Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Peptides*
Sulfhydryl Compounds*
Alanine/*analogs & derivatives
Biocompatible Materials/chemistry ; Hydrogels/chemistry ; Polyethylene Glycols/chemistry
Czasopismo naukowe
Tytuł:
High-Density Immobilization of TCEP on Silica Beads for Efficient Disulfide Reduction and Thiol Alkylation in Peptides.
Autorzy:
Schüttel M; Institute of Chemical Sciences and Engineering, School of Basic Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
Heinis C; Institute of Chemical Sciences and Engineering, School of Basic Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
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Źródło:
Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Feb 01; Vol. 25 (3), pp. e202300592. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfhydryl Compounds*
Silicon Dioxide*
Phosphines*
Sepharose ; Silica Gel ; Peptides/chemistry ; Indicators and Reagents ; Alkylation ; Disulfides/chemistry ; Oxidation-Reduction
Czasopismo naukowe
Tytuł:
Clinical trial: Combination allopurinol-thiopurine versus standard thiopurine in patients with IBD escalating to immunomodulators (the DECIDER study).
Autorzy:
Vasudevan A; Department of Gastroenterology and Hepatology, Eastern Health, Box Hill, Victoria, Australia.; Monash University, Eastern Health Clinical School, Box Hill, Victoria, Australia.
Con D; Department of Gastroenterology, The Austin Hospital, Melbourne, Victoria, Australia.
De Cruz P; Department of Gastroenterology, The Austin Hospital, Melbourne, Victoria, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, Victoria, Australia.
Sparrow MP; Department of Gastroenterology, Central Clinical School, Monash University and Alfred Health, Melbourne, Victoria, Australia.
Friedman AB; Department of Gastroenterology, Central Clinical School, Monash University and Alfred Health, Melbourne, Victoria, Australia.
Garg M; Department of Gastroenterology, Northern Health, Epping, Victoria, Australia.; Department of Medicine, Melbourne University, Melbourne, Australia.
Kashkooli S; Department of Gastroenterology, Northern Health, Epping, Victoria, Australia.
Gibson PR; Department of Gastroenterology, Central Clinical School, Monash University and Alfred Health, Melbourne, Victoria, Australia.
van Langenberg DR; Department of Gastroenterology and Hepatology, Eastern Health, Box Hill, Victoria, Australia.; Monash University, Eastern Health Clinical School, Box Hill, Victoria, Australia.
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Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2024 Feb; Vol. 59 (4), pp. 504-514. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article
MeSH Terms:
Azathioprine*/adverse effects
Inflammatory Bowel Diseases*/drug therapy
Inflammatory Bowel Diseases*/chemically induced
Purines*
Sulfhydryl Compounds*
Adult ; Humans ; Female ; Middle Aged ; Male ; Allopurinol/adverse effects ; Mercaptopurine ; Immunosuppressive Agents/adverse effects ; Treatment Outcome ; Drug Therapy, Combination ; Immunologic Factors/therapeutic use
Czasopismo naukowe
Tytuł:
Click chemistry in the synthesis of antibody-drug conjugates.
Autorzy:
Dudchak R; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilińskiego 1, Bialystok 15-089, Poland.
Podolak M; Department of Biotechnology, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilińskiego 1, Bialystok 15-089, Poland.
Holota S; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv 79010, Ukraine.
Szewczyk-Roszczenko O; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilińskiego 1, Bialystok 15-089, Poland.
Roszczenko P; Department of Biotechnology, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilińskiego 1, Bialystok 15-089, Poland.
Bielawska A; Department of Biotechnology, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilińskiego 1, Bialystok 15-089, Poland.
Lesyk R; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv 79010, Ukraine. Electronic address: dr_r_.
Bielawski K; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilińskiego 1, Bialystok 15-089, Poland.
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2024 Feb; Vol. 143, pp. 106982. Date of Electronic Publication: 2023 Nov 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Click Chemistry*
Azides*/chemistry
Maleimides*
Sulfhydryl Compounds*
Alkynes/chemistry ; Cycloaddition Reaction ; Copper/chemistry
Czasopismo naukowe
Tytuł:
Significantly Improved Cold Preservation of Rat Hind Limb Vascularized Composite Allografts Using the New PrC-210 Free Radical Scavenger.
Autorzy:
Fahl WE; Wisconsin Institute of Medical Research, University of Wisconsin-Madison, 111 Highland Ave., Madison, WI 53705, USA.
Nkana ZH; Division of Plastic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53705, USA.
Gitter MM; Wisconsin Institute of Medical Research, University of Wisconsin-Madison, 111 Highland Ave., Madison, WI 53705, USA.
Zeng W; Division of Plastic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53705, USA.
Dingle AM; Division of Plastic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53705, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 28; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Composite Tissue Allografts*/pathology
Reperfusion Injury*/pathology
Diamines*
Sulfhydryl Compounds*
Organ Preservation Solutions*
Rats ; Animals ; Free Radical Scavengers ; Caspase 3 ; Cytochromes c ; Quality of Life ; Rats, Inbred Lew ; Glutathione/pharmacology ; Allopurinol/pharmacology ; Insulin/pharmacology ; Ischemia ; Organ Preservation ; Cold Temperature ; Raffinose ; Adenosine
Czasopismo naukowe

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