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Tytuł:
Central nervous system sulfatide deficiency as a causal factor for bladder disorder in Alzheimer's disease.
Autorzy:
He S; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.
Qiu S; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.
Pan M; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.
Palavicini JP; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.; Division of Diabetes, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA.
Wang H; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.
Li X; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.
Bhattacharjee A; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.
Barannikov S; Department of Pathology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health San Antonio, San Antonio, Texas, USA.
Bieniek KF; Department of Pathology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health San Antonio, San Antonio, Texas, USA.
Dupree JL; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.; Research Division, McGuire Veterans Affairs Medical Center, Richmond, Virginia, USA.
Han X; Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio, San Antonio, Texas, USA.; Division of Diabetes, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Jul; Vol. 13 (7), pp. e1332.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Sulfoglycosphingolipids*
Alzheimer Disease*/genetics
Humans ; Mice ; Animals ; Urinary Bladder ; Myelin Sheath ; Spinal Cord
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Adult-Onset CNS Sulfatide Deficiency Causes Sex-Dependent Metabolic Disruption in Aging.
Autorzy:
Qiu S; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
He S; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Wang J; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Wang H; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Bhattacharjee A; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Li X; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Saeed M; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Dupree JL; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA 23284, USA.; McGuire Veterans Affairs Medical Center, Research Division, Richmond, VA 23249, USA.
Han X; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 22; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfoglycosphingolipids*/metabolism
Neuroinflammatory Diseases*
Mice ; Male ; Female ; Animals ; Mice, Knockout ; Central Nervous System/metabolism ; Aging ; Obesity ; Body Weight
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of sulfatide on peripheral nerves in metachromatic leukodystrophy.
Autorzy:
Farah MH; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Dali CÍ; Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark.
Groeschel S; Department of Pediatric Neurology, University Children's Hospital Tübingen, Tübingen, Germany.
Moldovan M; Department of Clinical Neurophysiology, Rigshospitalet, Copenhagen, Denmark.; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
Whiteman DAH; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Malanga CJ; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Krägeloh-Mann I; Department of Pediatric Neurology, University Children's Hospital Tübingen, Tübingen, Germany.
Li J; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Barton N; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Krarup C; Department of Clinical Neurophysiology, Rigshospitalet, Copenhagen, Denmark.; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2024 Feb; Vol. 11 (2), pp. 328-341. Date of Electronic Publication: 2023 Dec 26.
Typ publikacji:
Clinical Trial, Phase II; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukodystrophy, Metachromatic*/drug therapy
Psychosine/*analogs & derivatives
Child ; Humans ; Mice ; Animals ; Sulfoglycosphingolipids/pharmacology ; Cerebroside-Sulfatase ; Sciatic Nerve/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigation of Clinical Features and Association between Vascular Endothelial Injury Markers and Cytomegalovirus Infection Associated with Thrombotic Microangiopathy in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: Case-Based Research.
Autorzy:
Nimura T; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Aomura D; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Harada M; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Yamaguchi A; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Yamaka K; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Nakajima T; Department of Metabolic Regulation, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.; Center for Medical Education and Training, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Tanaka N; Department of Global Medical Research Promotion, Shinshu University Graduate School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.; International Relations Office, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.; Research Center for Social Systems, Shinshu University, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Ehara T; Department of Pathology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Hashimoto K; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
Kamijo Y; Department of Nephrology, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto 390-8621, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 09; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Vascular System Injuries*
Cytomegalovirus Infections*/complications
Thrombotic Microangiopathies*/diagnosis
Thrombotic Microangiopathies*/etiology
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/complications
Humans ; Female ; Middle Aged ; Antibodies, Antineutrophil Cytoplasmic ; Thrombomodulin ; Sulfoglycosphingolipids ; Cytomegalovirus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hibernation and plasma lipids in free-ranging brown bears-implications for diabetes.
Autorzy:
Tekin H; Bartholin Instituttet, Rigshospitalet, Copenhagen, Denmark.
Frøbert O; Department of Cardiology, Faculty of Health, Örebro University Hospital, Örebro, Sweden.; Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark.; Department of Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark.; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Græsli AR; Department of Forestry and Wildlife Management, Inland Norway University of Applied Sciences, Koppang, Norway.
Kindberg J; Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences, Umeå, Sweden.; Norwegian Institute for Nature Research, Trondheim, Norway.
Bilgin M; Lipidomics Core Facility, Danish Cancer Institute, Copenhagen, Denmark.
Buschard K; Bartholin Instituttet, Rigshospitalet, Copenhagen, Denmark.
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Źródło:
PloS one [PLoS One] 2023 Sep 05; Vol. 18 (9), pp. e0291063. Date of Electronic Publication: 2023 Sep 05 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ursidae*
Diabetes Mellitus, Type 1*
Animals ; Sulfoglycosphingolipids ; Adiposity ; Ethers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-Glycolipid Antibody Examination in Five EAE Models and Theiler's Virus Model of Multiple Sclerosis: Detection of Anti-GM1, GM3, GM4, and Sulfatide Antibodies in Relapsing-Remitting EAE.
Autorzy:
Moriguchi K; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.; Department of Internal Medicine, Japan Self Defense Forces Hanshin Hospital, Kawanishi City 666-0024, Hyogo, Japan.
Nakamura Y; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.; Department of Life Science, Faculty of Science and Engineering, Kindai University, Higashiosaka City 577-8502, Osaka, Japan.
Park AM; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.; Department of Arts and Science, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Sato F; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Kuwahara M; Department of Neurology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Khadka S; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.; Department of Immunology, School of Medicine, Duke University, Durham, NC 27710, USA.
Omura S; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Ahmad I; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Kusunoki S; Department of Neurology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.; Japan Community Health care Organization (JCHO) Headquarters, Minato City 108-8583, Tokyo, Japan.
Tsunoda I; Department of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 18; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 18.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*
Encephalomyelitis, Autoimmune, Experimental*
Theilovirus*
Animals ; Mice ; Mice, Inbred C57BL ; Sulfoglycosphingolipids ; Neoplasm Recurrence, Local ; Antibodies ; Myelin-Oligodendrocyte Glycoprotein ; Glycolipids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide.
Autorzy:
Wang-Eckhardt L; Institute of Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Becker I; Institute of Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Eckhardt M; Institute of Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
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Źródło:
Cells [Cells] 2021 Dec 13; Vol. 10 (12). Date of Electronic Publication: 2021 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme Inhibitors/*pharmacology
Galactosylceramides/*antagonists & inhibitors
Indoles/*pharmacology
Kidney Neoplasms/*drug therapy
Membrane Proteins/*genetics
Receptors, Progesterone/*genetics
Sulfoglycosphingolipids/*antagonists & inhibitors
Animals ; CHO Cells ; Cricetulus ; Galactosylceramides/biosynthesis ; Humans ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Membrane Proteins/antagonists & inhibitors ; N-Acylsphingosine Galactosyltransferase ; Receptors, Progesterone/antagonists & inhibitors ; Sulfoglycosphingolipids/metabolism ; Sulfotransferases/genetics ; Uridine Diphosphate Galactose/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer's disease-like neuroinflammation and cognitive impairment.
Autorzy:
Qiu S; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.
Palavicini JP; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Wang J; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.; Present Address: State Key Lab. of Environmental & Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hongkong, China.
Gonzalez NS; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.
He S; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.
Dustin E; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, 23284, USA.
Zou C; BRC Bioinformatics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY, 14853, USA.
Ding L; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.; College of Food Science and Engineering, Ocean University of China, Qingdao, 266003, China.
Bhattacharjee A; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.
Van Skike CE; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Galvan V; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA.; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Dupree JL; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, 23284, USA.; Research Division, McGuire Veterans Affairs Medical Center, Richmond, Virginia, 23249, USA.
Han X; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX, 78229, USA. .; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2021 Sep 15; Vol. 16 (1), pp. 64. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Disease Models, Animal*
Cognitive Dysfunction/*metabolism
Memory Disorders/*metabolism
Myelin Sheath/*chemistry
Neuroinflammatory Diseases/*metabolism
Sulfoglycosphingolipids/*metabolism
Age of Onset ; Alzheimer Disease/etiology ; Aminopyridines/toxicity ; Animals ; Apolipoproteins E/metabolism ; Brain Chemistry ; Central Nervous System/metabolism ; Cognitive Dysfunction/etiology ; Gene Expression Profiling ; Gliosis/metabolism ; Humans ; Memory Disorders/etiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Knockout, ApoE ; Morris Water Maze Test ; Neuroglia/enzymology ; Neuroglia/physiology ; Neuroinflammatory Diseases/etiology ; Open Field Test ; Proto-Oncogene Proteins/physiology ; Pyrroles/toxicity ; STAT3 Transcription Factor/physiology ; Sulfoglycosphingolipids/analysis ; Sulfotransferases/deficiency ; Trans-Activators/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Tumor ratio of unsaturated to saturated sulfatide species is associated with disease-free survival in intrahepatic cholangiocarcinoma.
Autorzy:
Huizing L; Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
Chen L; Department of Surgery, Maastricht University Medical Center and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO BOX 616, 6200 MD, Maastricht, The Netherlands.
Roeth AA; Department of Surgery, Maastricht University Medical Center and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO BOX 616, 6200 MD, Maastricht, The Netherlands.; Department of General, Visceral and Transplantation Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Heij LR; Department of General, Visceral and Transplantation Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Flinders B; Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
Bouwense SAW; Department of Surgery, Maastricht University Medical Center and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO BOX 616, 6200 MD, Maastricht, The Netherlands.
Balluff B; Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
Neumann UP; Department of Surgery, Maastricht University Medical Center and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO BOX 616, 6200 MD, Maastricht, The Netherlands.; Department of General, Visceral and Transplantation Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Heeren RMA; Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
Olde Damink SWM; Department of Surgery, Maastricht University Medical Center and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO BOX 616, 6200 MD, Maastricht, The Netherlands.; Department of General, Visceral and Transplantation Surgery, RWTH University Hospital Aachen, Aachen, Germany.
Vreeken RJ; Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.; Janssen Research & Development, Turnhoutseweg 30, 2340, Beerse, Belgium.
Schaap FG; Department of Surgery, Maastricht University Medical Center and NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO BOX 616, 6200 MD, Maastricht, The Netherlands. .; Department of General, Visceral and Transplantation Surgery, RWTH University Hospital Aachen, Aachen, Germany. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2023 Jun; Vol. 46 (3), pp. 629-642. Date of Electronic Publication: 2023 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Bile Duct Neoplasms*/pathology
Cholangiocarcinoma*/pathology
Humans ; Sulfoglycosphingolipids ; Disease-Free Survival ; Bile Ducts, Intrahepatic/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations.
Autorzy:
Marian OC; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.
Teo JD; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.
Lee JY; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.
Song H; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.
Kwok JB; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.; Brain and Mind Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.
Landin-Romero R; Brain and Mind Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.; School of Health Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.
Halliday G; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia.; Brain and Mind Centre, The University of Sydney, Camperdown, NSW, 2006, Australia.
Don AS; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, 2006, Australia. .; School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Mar 27; Vol. 11 (1), pp. 52. Date of Electronic Publication: 2023 Mar 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
C9orf72 Protein*/genetics
C9orf72 Protein*/metabolism
Frontotemporal Dementia*/genetics
Frontotemporal Dementia*/metabolism
Pick Disease of the Brain*/metabolism
Progranulins*/genetics
Progranulins*/metabolism
Animals ; Mice ; DNA-Binding Proteins/metabolism ; Galactosylceramides/metabolism ; Lipid Metabolism/genetics ; Mutation/genetics ; Myelin Sheath/metabolism ; Sulfoglycosphingolipids/metabolism ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sulfatide Deficiency, an Early Alzheimer's Lipidomic Signature, Causes Brain Ventricular Enlargement in the Absence of Classical Neuropathological Hallmarks.
Autorzy:
Palavicini JP; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Ding L; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Department of Biochemistry and Molecular Biology, Soochow University Medical College, Suzhou 215123, China.
Pan M; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Qiu S; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Wang H; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Shen Q; Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Dupree JL; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA 23284, USA.; Research Service, McGuire Veterans Affairs Medical Center, Richmond, VA 23249, USA.
Han X; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 23; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/pathology
Neurodegenerative Diseases*
Humans ; Animals ; Mice ; Sulfoglycosphingolipids ; Lipidomics ; Brain/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metabolic Regulation and Lipidomic Remodeling in Relation to Spermidine-induced Stress Tolerance to High Temperature in Plants.
Autorzy:
Li Z; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.; Institute of Turfgrass Science, Beijing Forestry University, Beijing 100083, China.
Cheng B; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Zhao Y; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Luo L; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Zhang Y; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Feng G; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Han L; Institute of Turfgrass Science, Beijing Forestry University, Beijing 100083, China.
Peng Y; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Zhang X; College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 13; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Spermidine*/pharmacology
Spermidine*/metabolism
Trifolium*/metabolism
Lipidomics ; Phosphatidylserines/metabolism ; Cardiolipins/metabolism ; Sulfoglycosphingolipids/metabolism ; Diglycerides/metabolism ; Temperature ; Ceramides/metabolism ; Phosphatidylcholines/metabolism ; Lysophospholipids/metabolism ; Phosphatidylinositols/metabolism ; Amino Acids/metabolism ; Vitamins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mass spectrometry imaging discriminates glioblastoma tumor cell subpopulations and different microvascular formations based on their lipid profiles.
Autorzy:
O'Neill KC; Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, NJ, 07110, USA.
Liapis E; Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, NJ, 07110, USA.
Harris BT; Departments of Neurology and Pathology, Georgetown University Medical Center, Washington, D.C., 20007, USA.
Perlin DS; Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, NJ, 07110, USA.; Department of Medical Sciences, Hackensack Meridian School of Medicine, Nutley, NJ, 07110, USA.
Carter CL; Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, NJ, 07110, USA. .; Department of Pathology, Hackensack Meridian School of Medicine, Nutley, NJ, 07110, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 12; Vol. 12 (1), pp. 17069. Date of Electronic Publication: 2022 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms*/genetics
Glioblastoma*/metabolism
Cardiolipins ; Ceramides ; Fatty Acids ; Gangliosides/metabolism ; Humans ; Ki-67 Antigen ; Mass Spectrometry ; Neoplasm Recurrence, Local ; Phosphates ; Phosphatidylinositols ; Sphingomyelins ; Sulfoglycosphingolipids ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GM3 Ganglioside Linked to Neurofibrillary Pathology in a Transgenic Rat Model for Tauopathy.
Autorzy:
Olešová D; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, 84510 Bratislava, Slovakia.; Laboratory of Biomedical Microbiology and Immunology, University of Veterinary Medicine and Pharmacy, 04181 Kosice, Slovakia.
Majerová P; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, 84510 Bratislava, Slovakia.
Hájek R; Waters Corporation, Stamford Avenue, Altrincham Road, Wilmslow SK9 4AX, UK.
Piešťanský J; Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Odbojarov 10, 83232 Bratislava, Slovakia.
Brumarová R; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc, and Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 6, 77900 Olomouc, Czech Republic.
Michalicová A; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, 84510 Bratislava, Slovakia.
Jurkanin B; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, 84510 Bratislava, Slovakia.
Friedecký D; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc, and Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 6, 77900 Olomouc, Czech Republic.
Kováč A; Institute of Neuroimmunology, Slovak Academy of Sciences, Dúbravská cesta 9, 84510 Bratislava, Slovakia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 22; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
G(M3) Ganglioside/*genetics
Neurofibrils/*genetics
Tauopathies/*genetics
tau Proteins/*genetics
Acidic Glycosphingolipids/genetics ; Acidic Glycosphingolipids/isolation & purification ; Aging/genetics ; Aging/pathology ; Animals ; Animals, Genetically Modified ; Brain/metabolism ; Brain/pathology ; Chromatography, Liquid ; Disease Models, Animal ; Humans ; Hydrophobic and Hydrophilic Interactions/drug effects ; Neurofibrils/pathology ; Rats ; Sulfoglycosphingolipids/isolation & purification ; Sulfoglycosphingolipids/metabolism ; Tauopathies/metabolism ; Tauopathies/pathology
Czasopismo naukowe
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Tytuł:
A Lipidomics Atlas of Selected Sphingolipids in Multiple Mouse Nervous System Regions.
Autorzy:
Wang C; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX 78229, USA.
Palavicini JP; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX 78229, USA.; Department of Medicine, Division of Diabetes, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Han X; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 4939 Charles Katz Drive, San Antonio, TX 78229, USA.; Department of Medicine, Division of Diabetes, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 21; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Sphingolipids/*genetics
Sphingolipids/*metabolism
Animals ; Atlases as Topic ; Central Nervous System/metabolism ; Ceramides/metabolism ; Cerebrosides/metabolism ; Lipid Metabolism/physiology ; Lipidomics/methods ; Male ; Mice ; Mice, Inbred C57BL ; Signal Transduction ; Sphingomyelins/metabolism ; Spinal Cord/metabolism ; Sulfoglycosphingolipids/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Treatment of adult metachromatic leukodystrophy model mice using intrathecal administration of type 9 AAV vector encoding arylsulfatase A.
Autorzy:
Miyake N; Department of Biochemistry and Molecular Biology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan. .
Miyake K; Department of Gene Therapy, Nippon Medical School, Tokyo, 113-8602, Japan.
Sakai A; Department of Pharmacology, Nippon Medical School, Tokyo, 113-8602, Japan.
Yamamoto M; Department of Biochemistry and Molecular Biology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.
Suzuki H; Department of Pharmacology, Nippon Medical School, Tokyo, 113-8602, Japan.
Shimada T; Department of Biochemistry and Molecular Biology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Oct 15; Vol. 11 (1), pp. 20513. Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebroside-Sulfatase/*genetics
Genetic Therapy/*methods
Leukodystrophy, Metachromatic/*therapy
Age Factors ; Animals ; Cerebellum/metabolism ; Cerebroside-Sulfatase/metabolism ; Dependovirus ; Disease Models, Animal ; Genetic Vectors ; Injections, Spinal ; Mice, Knockout ; Spinal Cord/metabolism ; Sulfoglycosphingolipids/metabolism ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Colonization factor CS30 from enterotoxigenic Escherichia coli binds to sulfatide in human and porcine small intestine.
Autorzy:
Von Mentzer A; Department of Microbiology and Immunology, Sahlgrenska Academy, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Wellcome Sanger Institute: Parasites and Microbes Programme, Hinxton, UK.
Zalem D; Department of Medical Biochemistry and Cell Biology, Sahlgrenska Academy, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Chrienova Z; Department of Medical Biochemistry and Cell Biology, Sahlgrenska Academy, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Chemistry, Faculty of Science, University of Hradec Králové, Hradec Králové, Czech Republic.
Teneberg S; Department of Medical Biochemistry and Cell Biology, Sahlgrenska Academy, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
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Źródło:
Virulence [Virulence] 2020 Dec; Vol. 11 (1), pp. 381-390.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Adhesion*
Enterotoxigenic Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
Fimbriae Proteins/*metabolism
Intestinal Mucosa/*microbiology
Intestine, Small/*microbiology
Sulfoglycosphingolipids/*metabolism
Animals ; Ceramides/analysis ; Fimbriae Proteins/genetics ; Glycosphingolipids/metabolism ; Humans ; Intestinal Mucosa/cytology ; Intestine, Small/cytology ; Swine ; Virulence Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clostridium Perfringens Epsilon Toxin Binds to Membrane Lipids and Its Cytotoxic Action Depends on Sulfatide.
Autorzy:
Gil C; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències, Universitat Autònoma de Barcelona, Bellaterra, Catalunya, Spain.
Dorca-Arévalo J; Laboratory of Cellular and Molecular Neuroscience, Department of Pathology and Experimental Therapeutics, School of Medicine, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain; IDIBELL-Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain.
Blasi J; Laboratory of Cellular and Molecular Neuroscience, Department of Pathology and Experimental Therapeutics, School of Medicine, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain; IDIBELL-Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain.
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Źródło:
PloS one [PLoS One] 2015 Oct 09; Vol. 10 (10), pp. e0140321. Date of Electronic Publication: 2015 Oct 09 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Toxins/*metabolism
Bacterial Toxins/*toxicity
Cytotoxins/*metabolism
Cytotoxins/*toxicity
Sulfoglycosphingolipids/*metabolism
Animals ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Detergents/pharmacology ; Dogs ; Madin Darby Canine Kidney Cells ; Phosphatidylinositols/metabolism ; Phosphatidylserines/metabolism ; Rats ; Rats, Sprague-Dawley ; Sulfates/metabolism ; Sulfoglycosphingolipids/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Structural, in silico, and functional analysis of a Disabled-2-derived peptide for recognition of sulfatides.
Autorzy:
Song W; Protein Signaling Domains Laboratory, Department of Biological Sciences, Fralin Life Sciences Institute, and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, VA, 24061, USA.
Gottschalk CJ; Research and Informatics, University Libraries, Biochemistry Department, and Center for Drug Discovery, Virginia Tech, Blacksburg, 24061, VA, USA.
Tang TX; Protein Signaling Domains Laboratory, Department of Biological Sciences, Fralin Life Sciences Institute, and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, VA, 24061, USA.
Biscardi A; Protein Signaling Domains Laboratory, Department of Biological Sciences, Fralin Life Sciences Institute, and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, VA, 24061, USA.
Ellena JF; Biomolecular Magnetic Resonance Facility, University of Virginia, Charlottesville, VA, 22904, USA.
Finkielstein CV; Integrated Cellular Responses Laboratory, Fralin Biomedical Research Institute, Department of Biological Sciences, and Center for Drug Discovery, Virginia Tech, Roanoke, VA, 24016, USA.
Brown AM; Research and Informatics, University Libraries, Biochemistry Department, and Center for Drug Discovery, Virginia Tech, Blacksburg, 24061, VA, USA.
Capelluto DGS; Protein Signaling Domains Laboratory, Department of Biological Sciences, Fralin Life Sciences Institute, and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, VA, 24061, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Aug 11; Vol. 10 (1), pp. 13520. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Computer Simulation*
Adaptor Proteins, Signal Transducing/*chemistry
Apoptosis Regulatory Proteins/*chemistry
Peptide Fragments/*chemistry
Peptide Fragments/*metabolism
Sulfoglycosphingolipids/*metabolism
Amino Acid Sequence ; Animals ; Humans ; Models, Molecular ; P-Selectin/metabolism ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pericellular proteolysis by matrix metalloproteinase-7 is differentially modulated by cholesterol sulfate, sulfatide, and cardiolipin.
Autorzy:
Yamamoto K; Graduate School of Nanobioscience, Yokohama City University, Japan; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, UK.
Miyazaki K
Higashi S
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Źródło:
The FEBS journal [FEBS J] 2014 Aug; Vol. 281 (15), pp. 3346-56. Date of Electronic Publication: 2014 Jul 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiolipins/*metabolism
Cholesterol Esters/*metabolism
Matrix Metalloproteinase 7/*metabolism
Sulfoglycosphingolipids/*metabolism
Binding, Competitive ; Cardiolipins/chemistry ; Cell Adhesion Molecules/chemistry ; Cell Line, Tumor ; Cell Membrane/enzymology ; Cholesterol Esters/chemistry ; Dipeptides/chemistry ; Dipeptides/pharmacology ; Fibronectins/chemistry ; Humans ; Hydroxamic Acids/chemistry ; Hydroxamic Acids/pharmacology ; Kinetics ; Matrix Metalloproteinase 7/chemistry ; Matrix Metalloproteinase Inhibitors/chemistry ; Matrix Metalloproteinase Inhibitors/pharmacology ; Protein Binding ; Proteolysis ; Sulfoglycosphingolipids/chemistry ; Kalinin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 117

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