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Wyszukujesz frazę ""Sulfonamides"" wg kryterium: Temat


Tytuł:
Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma.
Autorzy:
Tawfik HO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Saleh MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Ammara A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino 50019, Firenze, Italy.
Khaleel EF; Department of Medical Physiology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Badi R; Department of Medical Physiology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Khater YTT; Medical Experimental Research Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Rasheed RA; Department of Medical Histology and Cell Biology, Faculty of Medicine, King Salman International University, South Sinai 46511, Egypt.
Attia AA; Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Hefny SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Elkaeed EB; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia.
Nocentini A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino 50019, Firenze, Italy.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino 50019, Firenze, Italy.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, P.O. Box 33516, Kafrelsheikh 33516, Egypt.
Shaldam MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, P.O. Box 33516, Kafrelsheikh 33516, Egypt.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2024 Jan 25; Vol. 67 (2), pp. 1611-1623. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfonamides*/pharmacology
Sulfonamides*/therapeutic use
Sulfonamides*/chemistry
Glaucoma*/drug therapy
Humans ; Carbonic Anhydrase II ; Carbonic Anhydrase Inhibitors/pharmacology ; Carbonic Anhydrase Inhibitors/therapeutic use ; Carbonic Anhydrase Inhibitors/chemistry ; Molecular Structure ; Structure-Activity Relationship ; Molecular Docking Simulation ; Sulfanilamide ; Carbonic Anhydrase IX/metabolism
Czasopismo naukowe
Tytuł:
The effect of combination therapy with intravitreal bevacizumab and topical timolol-dorzolamide eye drops on diabetic macular edema: a double-blind randomized controlled trial.
Autorzy:
Fekri S; Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rabiei A; Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran. rabiei_.; Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. rabiei_.
Hooshmandi S; Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nouri H; Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran. .; School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. .
Abtahi SH; Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło:
International ophthalmology [Int Ophthalmol] 2024 Feb 20; Vol. 44 (1), pp. 101. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Diabetic Retinopathy*/complications
Diabetic Retinopathy*/diagnosis
Diabetic Retinopathy*/drug therapy
Macular Edema*/diagnosis
Macular Edema*/drug therapy
Macular Edema*/etiology
Diabetes Mellitus*
Sulfonamides*
Thiophenes*
Humans ; Bevacizumab ; Timolol ; Lubricant Eye Drops
Czasopismo naukowe
Tytuł:
Investigating the impacts of airborne dust on herbicide performance on Amaranthus retroflexus.
Autorzy:
Sharifi Kalyani F; Department of Plant Production and Genetics, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Babaei S; Department of Plant Production and Genetics, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran. .; Crop, Soil, and Environmental Management Program, School of Agricultural Sciences, Southern Illinois University, Carbondale, IL, 62901, USA. .
Zafarsohrabpour Y; Department of Plant Production and Genetics, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Nosratti I; Department of Plant Production and Genetics, Faculty of Agriculture and Natural Resources, Razi University, Kermanshah, Iran.
Gage K; Crop, Soil, and Environmental Management Program, School of Agricultural Sciences, Southern Illinois University, Carbondale, IL, 62901, USA.
Sadeghpour A; Crop, Soil, and Environmental Management Program, School of Agricultural Sciences, Southern Illinois University, Carbondale, IL, 62901, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 15; Vol. 14 (1), pp. 3785. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Herbicides*/pharmacology
Amaranthus*
Pyridines*
Benzothiadiazines*
Carboxylic Acids*
Arylsulfonates*
Pyrimidines*
Sulfonamides*
Plant Weeds ; Herbicide Resistance
Czasopismo naukowe
Tytuł:
ACE2 improves endothelial cell function and reduces acute lung injury by downregulating FAK expression.
Autorzy:
He Y; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China.
Gang B; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China.
Zhang M; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China.
Bai Y; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China.
Wan Z; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China.
Pan J; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China.
Liu J; College of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu, Sichuan Province, PR China.
Liu G; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China. Electronic address: .
Gu W; Department of Biochemistry and Molecular Biology, School of Laboratory Medicine, and Anhui Province Key Laboratory of Cancer Translational Medicine, Bengbu Medical University, 2600 Donghai Avenue, Bengbu, Anhui Province 233030, PR China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Feb 15; Vol. 128, pp. 111535. Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/drug therapy
Indoles*
Pyridines*
Respiratory Distress Syndrome*/metabolism
Sulfonamides*
Animals ; Mice ; Angiotensin-Converting Enzyme 2/metabolism ; Endothelial Cells/metabolism ; Focal Adhesion Protein-Tyrosine Kinases/metabolism ; Focal Adhesion Protein-Tyrosine Kinases/therapeutic use ; Lung/metabolism ; Peptidyl-Dipeptidase A/metabolism
Czasopismo naukowe
Tytuł:
Sivelestat ameliorates sepsis-induced myocardial dysfunction by activating the PI3K/AKT/mTOR signaling pathway.
Autorzy:
Geng H; Department of Intensive Care Unit, Baoding First Central Hospital, Baoding, China.
Zhang H; Department of General Surgery, Baoding First Central Hospital, Baoding, China.
Cheng L; Department of Intensive Care Unit, Baoding First Central Hospital, Baoding, China.
Dong S; Department of Emergency, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Feb 15; Vol. 128, pp. 111466. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiomyopathies*
Sepsis*/metabolism
Sulfonamides*
Glycine/*analogs & derivatives
Rats ; Animals ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Lipopolysaccharides/pharmacology ; Rats, Sprague-Dawley ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Apoptosis
Czasopismo naukowe
Tytuł:
Biomarker-driven phase 2 umbrella trial: Clinical efficacy of olaparib monotherapy and combination with ceralasertib (AZD6738) in small cell lung cancer.
Autorzy:
Park S; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kim YJ; Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Min YJ; Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.
Mortimer PGS; R&D Oncology, AstraZeneca, Cambridge, UK.
Kim HJ; External R&D, R&D Oncology, AstraZeneca, Seoul, Korea.
Smith SA; R&D Oncology, AstraZeneca, Cambridge, UK.
Dean E; R&D Oncology, AstraZeneca, Cambridge, UK.
Jung HA; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Sun JM; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Park WY; Samsung Genome Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Ahn JS; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Ahn MJ; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Lee SH; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Park K; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
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Źródło:
Cancer [Cancer] 2024 Feb 15; Vol. 130 (4), pp. 541-552. Date of Electronic Publication: 2023 Oct 16.
Typ publikacji:
Clinical Trial, Phase II; Journal Article
MeSH Terms:
Small Cell Lung Carcinoma*/drug therapy
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/chemically induced
Ovarian Neoplasms*/drug therapy
Pyrimidines*
Piperazines*
Sulfonamides*
Indoles*
Morpholines*
Humans ; Female ; Treatment Outcome ; Phthalazines/adverse effects
Czasopismo naukowe
Tytuł:
Comparative efficacy and safety of Sofosbuvir/Velpatasvir and Danoprevir for the treatment of chronic hepatitis C: the real-world data in China.
Autorzy:
Zhou Y; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.
Liang M; Department of Infectious disease, The First people's hospital of Foshan, Foshan City, Guangdong Province, China.
Li Y; Department of General Practice, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou City, Guangdong Province, China.
Chen X; Department of Infectious Diseases, Yangjiang Public Health Hospital, Yangjiang City, Guangdong Province, China.
Yang J; Clinical Medicine Department of Southwest Medical University, Luzhou City, Sichuan Province, China.
Bai H; Department of Infectious disease, The First people's hospital of Foshan, Foshan City, Guangdong Province, China.
Long Y; Department of Infectious Diseases, The Eighth Hospital of Guangzhou Medical University, Guangzhou City, Guangdong Province, China.
Zhang X; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.
Lin C; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China. .
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2024 Feb 14; Vol. 24 (1), pp. 73. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Benzimidazoles*
Benzopyrans*
Carbamates*
Cyclopropanes*
Drug Combinations*
Hepatitis C*/drug therapy
Hepatitis C, Chronic*/genetics
Isoindoles*
Lactams, Macrocyclic*
Proline*/analogs & derivatives
Sulfonamides*
Humans ; Antiviral Agents/adverse effects ; China ; Genotype ; Hepacivirus/genetics ; Heterocyclic Compounds, 4 or More Rings/adverse effects ; Liver Cirrhosis/drug therapy ; Retrospective Studies ; Ribavirin/adverse effects ; Sofosbuvir/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Effects of HMGB1/TLR4 on secretion IL-10 and VEGF in human jaw bone-marrow mesenchymal stem cells.
Autorzy:
Kong J; Jinan Stomatological Hospital, Department of Prosthodontics, Shandong Province, China.
Cheng W; Jinan Stomatological Hospital, Department of Prosthodontics, Shandong Province, China.
Chang L; Jinan Stomatological Hospital, Department of Periodontist, Shandong Province, China.
Yu J; Jinan Stomatological Hospital, Department of Prosthodontics, Shandong Province, China.
Wang R; Jinan Stomatological Hospital, Department of Prosthodontics, Shandong Province, China.
Xie J; Jinan Stomatological Hospital, Department of Prosthodontics, Shandong Province, China.
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Źródło:
Journal of applied oral science : revista FOB [J Appl Oral Sci] 2024 Feb 12; Vol. 32, pp. e20230304. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
HMGB1 Protein*/pharmacology
HMGB1 Protein*/genetics
HMGB1 Protein*/metabolism
Mesenchymal Stem Cells*/metabolism
Sulfonamides*
Humans ; Interleukin-10 ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Vascular Endothelial Growth Factor A ; Bone Marrow/metabolism ; RNA, Messenger
Czasopismo naukowe
Tytuł:
Real-world Experience of Abrocitinib Treatment in Patients with Atopic Dermatitis and Hand Eczema: Up to 28-week Results from the BioDay Registry.
Autorzy:
Kamphuis E; Department of Dermatology, University Medical Center Groningen, Groningen, The Netherlands.
Boesjes CM; Department of Dermatology, University Medical Center Utrecht, Utrecht, The Netherlands.
Loman L; Department of Dermatology, University Medical Center Groningen, Groningen, The Netherlands.
Kamsteeg M; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Haeck I; Department of Dermatology, Reinier de Graaf Gasthuis, Delft, The Netherlands.
Van Lynden-van Nes AMT; Department of Dermatology, Meander Medical Center, Amersfoort, The Netherlands.
Politiek K; Department of Dermatology, Medical Center Leeuwarden, Leeuwarden, The Netherlands.
Van der Gang LF; Department of Dermatology, University Medical Center Utrecht, Utrecht, The Netherlands.
De Graaf M; Department of Dermatology, University Medical Center Utrecht, Utrecht, The Netherlands.
De Bruin-Weller MS; Department of Dermatology, University Medical Center Utrecht, Utrecht, The Netherlands.
Schuttelaar MLA; Department of Dermatology, University Medical Center Groningen, Groningen, The Netherlands. .
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Źródło:
Acta dermato-venereologica [Acta Derm Venereol] 2024 Feb 07; Vol. 104, pp. adv19454. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Dermatitis, Atopic*
Eczema*
Pyrimidines*
Sulfonamides*
Humans ; Prospective Studies ; Registries ; Treatment Outcome ; Severity of Illness Index ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Valganciclovir modulates the tumor necrosis factor axis molecules expression and CD4+ T-cell subsets in disseminated Kaposi Sarcoma patients.
Autorzy:
Ramon-Luing LA; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Flores-Gonzalez J; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Angel García-Rojas L; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Islas-Muñoz B; Infectious Diseases Department, Instituto Nacional de Cancerología, Mexico City, Mexico.
Volkow-Fernández P; Infectious Diseases Department, Instituto Nacional de Cancerología, Mexico City, Mexico.
Chavez-Galan L; Laboratory of Integrative Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2024 Feb 07; Vol. 215 (2), pp. 190-201.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Sarcoma, Kaposi*/drug therapy
Sarcoma, Kaposi*/metabolism
HIV Infections*/metabolism
Sulfonamides*
Humans ; Valganciclovir/metabolism ; Valganciclovir/therapeutic use ; CD4-Positive T-Lymphocytes/metabolism ; T-Lymphocyte Subsets ; CD8-Positive T-Lymphocytes/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Viral Load
Czasopismo naukowe
Tytuł:
Potential anti- Pythium insidiosum therapeutics identified through screening of agricultural fungicides.
Autorzy:
Yolanda H; Program in Translational Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.; Department of Parasitology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Jearawuttanakul K; Excellent Center for Drug Discovery, Faculty of Science, Mahidol University, Bangkok, Thailand.
Wannalo W; Excellent Center for Drug Discovery, Faculty of Science, Mahidol University, Bangkok, Thailand.
Kanjanasirirat P; Excellent Center for Drug Discovery, Faculty of Science, Mahidol University, Bangkok, Thailand.
Borwornpinyo S; Excellent Center for Drug Discovery, Faculty of Science, Mahidol University, Bangkok, Thailand.; Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Rujirawat T; Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Payattikul P; Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Kittichotirat W; Bioinformatics and Systems Biology Program, School of Bioresources and Technology and School of Information Technology, King Mongkut's University of Technology Thonburi, Bangkhuntien, Bangkok, Thailand.; Systems Biology and Bioinformatics Research Group, Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi, Bangkhuntien, Bangkok, Thailand.
Wichadakul D; Department of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.; Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Krajaejun T; Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2024 Feb 06; Vol. 12 (2), pp. e0162023. Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Pythium*/metabolism
Fungicides, Industrial*/metabolism
Fungicides, Industrial*/pharmacology
Fungicides, Industrial*/therapeutic use
Pythiosis*/drug therapy
Pythiosis*/microbiology
Imidazoles*
Sulfonamides*
Animals ; Humans ; Molecular Docking Simulation ; Cytochromes b/metabolism ; Mammals
Czasopismo naukowe
Tytuł:
Effect of quercetin, L-ergothioneine and H89 on sperm motility and kinematic pattern, plasma membrane functionality and in vitro heterologous fertilizing capacity of cryopreserved equine semen.
Autorzy:
Lobo MEA; Faculty of Veterinary Medicine and Zootechnics, Institución Universitaria Visión de las Américas Medellín, Colombia.
Londoño GC; Department of Agronomic Sciences. Faculty of Agricultural Sciences, Universidad Nacional de Colombia, Medellín, Colombia.
Rojano BA; Faculty of Sciences, Universidad Nacional de Colombia, Medellín, Colombia.
Betancur GR; Faculty of Agricultural Sciences, Universidad Nacional de Colombia, Cra 65 # 59A-110, Medellín, Colombia. Electronic address: .
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Źródło:
Journal of equine veterinary science [J Equine Vet Sci] 2024 Feb; Vol. 133, pp. 105013. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Ergothioneine*/pharmacology
Aging, Premature*/veterinary
Isoquinolines*
Sulfonamides*
Male ; Animals ; Horses ; Semen ; Sperm Motility ; Quercetin/pharmacology ; Biomechanical Phenomena ; Fertilization ; Cryopreservation/veterinary ; Cell Membrane
Czasopismo naukowe
Tytuł:
High-throughput drug screen identifies calcium and calmodulin inhibitors that reduce JCPyV infection.
Autorzy:
Bond ACS; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
Crocker MA; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
Wilczek MP; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
DuShane JK; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
Sandberg AL; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
Bennett LJ; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
Leclerc NR; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA.
Maginnis MS; Department of Molecular and Biomedical Sciences, The University of Maine, Orono, ME, 04469, USA; Graduate School of Biomedical Science and Engineering, Orono, ME, 04469, USA. Electronic address: .
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Źródło:
Antiviral research [Antiviral Res] 2024 Feb; Vol. 222, pp. 105817. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*
Leukoencephalopathy, Progressive Multifocal*/drug therapy
Leukoencephalopathy, Progressive Multifocal*/genetics
Polyomavirus Infections*
JC Virus*/genetics
Sulfonamides*
Humans ; Calcium ; Calmodulin ; Simian virus 40 ; Antiviral Agents/pharmacology
Czasopismo naukowe
Tytuł:
2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction.
Autorzy:
Kishigami T; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan; Department of Cardiovascular Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Ishikane S; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan. Electronic address: .
Arioka M; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Igawa K; Department of Chemistry, Faculty of Advanced Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto, 860-8555, Japan.
Nishimura Y; Department of Cardiovascular Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Takahashi-Yanaga F; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.
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Źródło:
Journal of pharmacological sciences [J Pharmacol Sci] 2024 Feb; Vol. 154 (2), pp. 97-107. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Ventricular Remodeling*
Myocardial Infarction*/drug therapy
Pyrazoles*
Sulfonamides*
Animals ; Mice ; Celecoxib/pharmacology ; Celecoxib/therapeutic use ; Stroke Volume ; Ventricular Function, Left ; Macrophages ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Development of a tetrahydroindazolone-based HDAC6 inhibitor with in-vivo anti-arthritic activity.
Autorzy:
Yang HM; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, South Korea; Chong Kun Dang Research Institute, CKD Pharmaceuticals, Gyeonggi-do 16995, South Korea.
Lee C; Chong Kun Dang Research Institute, CKD Pharmaceuticals, Gyeonggi-do 16995, South Korea.
Min J; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, South Korea; Chong Kun Dang Research Institute, CKD Pharmaceuticals, Gyeonggi-do 16995, South Korea.
Ha N; Chong Kun Dang Research Institute, CKD Pharmaceuticals, Gyeonggi-do 16995, South Korea.
Bae D; Chong Kun Dang Research Institute, CKD Pharmaceuticals, Gyeonggi-do 16995, South Korea.
Nam G; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, South Korea.
Park HJ; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, South Korea. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Feb 01; Vol. 99, pp. 117587. Date of Electronic Publication: 2024 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfonamides*
Arthritis, Rheumatoid*/drug therapy
Thiophenes*
Rats ; Animals ; Histone Deacetylase 6 ; Imidazoles ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł:
Senolytic treatment alleviates doxorubicin-induced chemobrain.
Autorzy:
Budamagunta V; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.; Genetics and Genomics Graduate Program, Genetics Institute, University of Florida, Gainesville, Florida, USA.; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Kumar A; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.
Rani A; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.
Manohar Sindhu S; Genetics and Genomics Graduate Program, Genetics Institute, University of Florida, Gainesville, Florida, USA.
Yang Y; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Zhou D; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Foster TC; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.; Genetics and Genomics Graduate Program, Genetics Institute, University of Florida, Gainesville, Florida, USA.
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Źródło:
Aging cell [Aging Cell] 2024 Feb; Vol. 23 (2), pp. e14037. Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Chemotherapy-Related Cognitive Impairment*
Sulfonamides*
Humans ; Senotherapeutics ; Doxorubicin/adverse effects ; Aniline Compounds ; Cellular Senescence
Czasopismo naukowe
Tytuł:
Glycyrrhizin attenuates myocardial ischemia reperfusion injury by suppressing Inflammation, oxidative stress, and ferroptosis via the HMGB1-TLR4-GPX4 pathway.
Autorzy:
Zhu K; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Shanxi Academy of Advanced Research and Innovation, Taiyuan, 030032, China. Electronic address: doctor_kaiyi_.
Fan R; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cao Y; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang W; Department of Neurosurgery, Beijing Children's Hospital, Capital Medical University, Beijing, 100045, China.
Zhang Z; Shanxi Academy of Advanced Research and Innovation, Taiyuan, 030032, China; Department of Pulmonary and Critical Care Medicine, Aerospace Center Hospital, Beijing, 100049, China.
Zhou Q; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ren J; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shi X; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gao Y; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Key Laboratory of Cellular Physiology, Shanxi Province, Key Laboratory of Cellular Physiology (Shanxi Medical University), Ministry of Education, China. Electronic address: .
Guo X; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
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Źródło:
Experimental cell research [Exp Cell Res] 2024 Feb 01; Vol. 435 (1), pp. 113912. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Myocardial Reperfusion Injury*/metabolism
Ferroptosis*
HMGB1 Protein*/metabolism
Reperfusion Injury*/pathology
Sulfonamides*
Rats ; Animals ; Glycyrrhizic Acid/pharmacology ; Toll-Like Receptor 4/metabolism ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Rats, Sprague-Dawley ; Apoptosis ; Oxidative Stress ; Inflammation/drug therapy ; Inflammation/pathology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł:
Prospective study of an adalimumab combined with partial enteral nutrition in the induction period of Crohn's disease.
Autorzy:
Zhou S; Department of Gastroenterology, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou, 515041, China.
Huang Z; Department of Gastroenterology, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou, 515041, China.
Hou W; Department of Gastroenterology, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou, 515041, China.
Lin Y; Department of Gastroenterology, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou, 515041, China.
Yu J; Department of Gastroenterology, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou, 515041, China. .
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Źródło:
Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2024 Feb; Vol. 73 (2), pp. 199-209. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Crohn Disease*/therapy
Sulfonamides*
Humans ; Adalimumab/therapeutic use ; Prospective Studies ; Enteral Nutrition ; Quality of Life ; Remission Induction ; C-Reactive Protein ; Leukocyte L1 Antigen Complex
Czasopismo naukowe
Tytuł:
Real-World Safety and Effectiveness of an 8-Week Regimen of Glecaprevir/Pibrentasvir in Patients with Hepatitis C and Cirrhosis.
Autorzy:
Lu M; Department of Public Health Sciences, Henry Ford Health, One Ford Place, Detroit, MI, 48202, USA. .; Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, USA. .
Rupp LB; Department of Health Policy and Health Services Research, Henry Ford Health, Detroit, MI, USA.
Melkonian C; Department of Public Health Sciences, Henry Ford Health, One Ford Place, Detroit, MI, 48202, USA.
Trudeau S; Department of Public Health Sciences, Henry Ford Health, One Ford Place, Detroit, MI, 48202, USA.
Daida YG; Center for Integrated Health Care Research, Kaiser Permanente Hawaii, Honolulu, HI, USA.
Schmidt MA; Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Gordon SC; Department of Gastroenterology and Hepatology, Henry Ford Health, Detroit, MI, USA.; School of Medicine, Wayne State University, Detroit, MI, USA.
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Źródło:
Advances in therapy [Adv Ther] 2024 Feb; Vol. 41 (2), pp. 744-758. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Liver Cirrhosis*/complications
Liver Cirrhosis*/drug therapy
Hepatitis C, Chronic*/complications
Hepatitis C, Chronic*/drug therapy
Hepatitis C, Chronic*/genetics
Sulfonamides*
Aminoisobutyric Acids*
Lactams, Macrocyclic*
Cyclopropanes*
Benzimidazoles*
Leucine/*analogs & derivatives
Proline/*analogs & derivatives
Humans ; Cohort Studies ; Treatment Outcome ; Quinoxalines/adverse effects ; Pyrrolidines/therapeutic use ; Hepacivirus/genetics ; Antiviral Agents/adverse effects ; Genotype
Czasopismo naukowe
Tytuł:
Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors.
Autorzy:
Tamhaev R; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
Grosjean E; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
Ahamed H; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
Chebaiki M; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
Rodriguez F; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
Recchia D; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Degiacomi G; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Pasca MR; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, 27100 Pavia, Italy.
Maveyraud L; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France. Electronic address: .
Mourey L; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France. Electronic address: .
Lherbet C; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2024 Feb; Vol. 143, pp. 107032. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antitubercular Agents*/pharmacology
Antitubercular Agents*/chemistry
Mycobacterium tuberculosis*
Imidazoles*
Sulfonamides*
Thiophenes*
Humans ; Ether ; Ethers ; Binding Sites ; Ethyl Ethers ; Bacterial Proteins/metabolism
Czasopismo naukowe

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