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Tytuł:
Antiproliferative effects of sulphonamide carbonic anhydrase inhibitors C18, SLC-0111 and acetazolamide on bladder, glioblastoma and pancreatic cancer cell lines.
Autorzy:
Mussi S; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Rezzola S; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Chiodelli P; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Nocentini A; NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, Florence, Italy.
Supuran CT; NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, Florence, Italy.
Ronca R; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 280-286.
Typ publikacji:
Journal Article
MeSH Terms:
Acetazolamide/*pharmacology
Antineoplastic Agents/*pharmacology
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Sulfonamides/*pharmacology
Acetazolamide/chemical synthesis ; Acetazolamide/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The discovery of a novel series of potential ERRα inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo .
Autorzy:
Gao Z; School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, P. R. China.
Wang T; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Li R; School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, P. R. China.
Du Y; School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, P. R. China.
Lv H; School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, P. R. China.
Zhang L; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Chen H; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Shi X; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Li Q; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Shen J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, P. R. China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 125-134.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Discovery*
Antineoplastic Agents/*pharmacology
Nitrobenzenes/*pharmacology
Receptors, Estrogen/*metabolism
Sulfonamides/*pharmacology
Triple Negative Breast Neoplasms/*drug therapy
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Female ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Nitrobenzenes/chemical synthesis ; Nitrobenzenes/chemistry ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
Autorzy:
Bonardi A; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSAR, University of Firenze, Florence, Italy.
Bua S; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.
Combs J; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Lomelino C; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Andring J; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Osman SM; Chemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Toti A; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.
Di Cesare Mannelli L; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.
Gratteri P; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSAR, University of Firenze, Florence, Italy.
Ghelardini C; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.
McKenna R; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Nocentini A; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.
Supuran CT; Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 930-939.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Carbonic Anhydrase IX/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Sulfonamides/*pharmacology
Antigens, Neoplasm/metabolism ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors.
Autorzy:
Testa C; Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology', Department of Chemistry 'Ugo Schiff', University of Florence, Sesto Fiorentino, Italy.
Papini AM; Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology', Department of Chemistry 'Ugo Schiff', University of Florence, Sesto Fiorentino, Italy.
Zeidler R; Research Group Therapeutic Antibodies, Helmholtz Centre Munich German Research Centre for Environmental Health, Munich, Germany.; Department of Otorhinolaryngology, Klinikum der Universitaet, Munich, Germany.
Vullo D; NEUROFARBA Dept., Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, via Ugo Schff 6, Sesto Fiorentino (Florence), 50019 Italy.
Carta F; NEUROFARBA Dept., Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, via Ugo Schff 6, Sesto Fiorentino (Florence), 50019 Italy.
Supuran CT; NEUROFARBA Dept., Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, via Ugo Schff 6, Sesto Fiorentino (Florence), 50019 Italy.
Rovero P; Interdepartmental Research Unit of Peptide and Protein Chemistry and Biology', Department of Chemistry 'Ugo Schiff', University of Florence, Sesto Fiorentino, Italy.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 592-596.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal/*pharmacology
Carbonic Anhydrase Inhibitors/*pharmacology
Neoplasms/*drug therapy
Small Molecule Libraries/*pharmacology
Sulfonamides/*pharmacology
Antibodies, Monoclonal/chemistry ; Antigens, Neoplasm/metabolism ; Carbonic Anhydrase IX/antagonists & inhibitors ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Carbonic Anhydrases/metabolism ; Dose-Response Relationship, Drug ; Humans ; Molecular Structure ; Molecular Weight ; Neoplasms/metabolism ; Small Molecule Libraries/chemical synthesis ; Small Molecule Libraries/chemistry ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Diversely substituted sulfamides for fragment-based drug discovery of carbonic anhydrase inhibitors: synthesis and inhibitory profile.
Autorzy:
Sharonova T; Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
Zhmurov P; Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
Kalinin S; Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
Nocentini A; Neurofarba Department, Universita Degli Studi di Firenze, Florence, Italy.
Angeli A; Neurofarba Department, Universita Degli Studi di Firenze, Florence, Italy.
Ferraroni M; Neurofarba Department, Universita Degli Studi di Firenze, Florence, Italy.
Korsakov M; Pharmaceutical Technology Transfer Center, Ushinsky Yaroslavl State Pedagogical University, Yaroslavl, Russia.
Supuran CT; Neurofarba Department, Universita Degli Studi di Firenze, Florence, Italy.
Krasavin M; Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 857-865.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Discovery*
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Sulfonamides/*pharmacology
Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Novel 2-substituted thioquinazoline-benzenesulfonamide derivatives as carbonic anhydrase inhibitors with potential anticancer activity.
Autorzy:
Abdel-Mohsen HT; Department of Chemistry of Natural and Microbial Products, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Cairo, Egypt.
Omar MA; Department of Chemistry of Natural and Microbial Products, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Cairo, Egypt.
Petreni A; Department NEUROFARBA-Pharmaceutical and Nutraceutical Section, University of Firenze, Firenze, Italy.
Supuran CT; Department NEUROFARBA-Pharmaceutical and Nutraceutical Section, University of Firenze, Firenze, Italy.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2022 Dec; Vol. 355 (12), pp. e2200180. Date of Electronic Publication: 2022 Sep 03.
Typ publikacji:
Journal Article
MeSH Terms:
Carbonic Anhydrase Inhibitors*/pharmacology
Carbonic Anhydrase Inhibitors*/chemistry
Sulfonamides*/pharmacology
Sulfonamides*/chemistry
Molecular Docking Simulation ; Structure-Activity Relationship ; Carbonic Anhydrase II ; Amino Acids ; Molecular Structure
Czasopismo naukowe
Szczegóły
Tytuł:
Novel sulphonamide-bearing methoxyquinazolinone derivatives as anticancer and apoptosis inducers: synthesis, biological evaluation and in silico studies.
Autorzy:
Alqahtani AS; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ghorab MM; Department of Drug Radiation Research, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Nasr FA; Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ahmed MZ; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Al-Mishari AA; Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Attia SM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 86-99.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Docking Simulation*
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Quinazolinones/*pharmacology
Sulfonamides/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Quinazolinones/chemical synthesis ; Quinazolinones/chemistry ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Synthesis, molecular modelling and QSAR study of new N- phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity.
Autorzy:
Said MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
George RF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Petreni A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Florence, Italy.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Florence, Italy.
Mohamed NM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Modern University for Technology and Information MTI, Cairo, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 701-717.
Typ publikacji:
Journal Article
MeSH Terms:
Quantitative Structure-Activity Relationship*
Acetanilides/*pharmacology
Antineoplastic Agents/*pharmacology
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Indoles/*pharmacology
Sulfonamides/*pharmacology
Acetanilides/chemical synthesis ; Acetanilides/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Indoles/chemical synthesis ; Indoles/chemistry ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Models, Molecular ; Molecular Structure ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Leukemic stem cells and therapy resistance in acute myeloid leukemia.
Autorzy:
Stelmach P; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM, gGmbH); Department of Medicine V, Heidelberg University Hospital.
Trumpp A; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM, gGmbH); Faculty of Biosciences, Heidelberg University; German Cancer Consortium (DKTK), Heidelberg. .
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Źródło:
Haematologica [Haematologica] 2023 Feb 01; Vol. 108 (2), pp. 353-366. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Recenzja
MeSH Terms:
Sulfonamides*
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Humans ; Azacitidine/therapeutic use ; Neoplastic Stem Cells
Recenzja
Szczegóły
Tytuł:
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.
Autorzy:
Fanfrlík J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. .
Brynda J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. .
Kugler M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. .
Lepšík M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. .
Pospíšilová K; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. .
Holub J; Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68 Husinec-Řež, Czech Republic.
Hnyk D; Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68 Husinec-Řež, Czech Republic.
Nekvinda J; Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68 Husinec-Řež, Czech Republic.
Grüner B; Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68 Husinec-Řež, Czech Republic.
Řezáčová P; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. .
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Źródło:
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2023 Jan 18; Vol. 25 (3), pp. 1728-1733. Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfonamides*
Carbonic Anhydrase II*
Ligands ; Sulfanilamide ; Crystallography, X-Ray
Czasopismo naukowe
Szczegóły
Tytuł:
Oral and Inhaled Fosamprenavir Reverses Pepsin-Induced Damage in a Laryngopharyngeal Reflux Mouse Model.
Autorzy:
Johnston N; Department of Otolaryngology and Communication Science, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Samuels TL; Department of Otolaryngology and Communication Science, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Goetz CJ; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Arnold LA; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Smith BC; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Seabloom D; Department of Otolaryngology Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, U.S.A.
Wuertz B; Department of Otolaryngology Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, U.S.A.
Ondrey F; Department of Otolaryngology Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, U.S.A.
Wiedmann TS; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota, U.S.A.
Vuksanovic N; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Silvaggi NR; Department of Chemistry and Biochemistry, Milwaukee Institute for Drug Discovery, University of Wisconsin, Milwaukee, Wisconsin, U.S.A.
MacKinnon AC; Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama, U.S.A.
Miller J; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Bock J; Department of Otolaryngology and Communication Science, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Blumin JH; Department of Otolaryngology and Communication Science, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
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Źródło:
The Laryngoscope [Laryngoscope] 2023 Jan; Vol. 133 Suppl 1, pp. S1-S11. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Laryngopharyngeal Reflux*/diagnosis
Larynx*/metabolism
Sulfonamides*/pharmacology
Carbamates*/pharmacology
Furans*/pharmacology
Animals ; Mice ; Pepsin A/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Impact of tablet crushing on the dissolution of venetoclax.
Autorzy:
Yasu T; Department of Medicinal Therapy Research, Pharmaceutical Education and Research Center, Meiji Pharmaceutical University, 2-522-1, Noshio, Kiyose, Tokyo, 204-8588, Japan. .; Department of Pharmacy, Tokyo Metropolitan Bokutoh Hospital, 4-23-15 Koutoubashi, Sumida-Ku, Tokyo, 130-8575, Japan. .; Bokutoh Hospital-Meiji Pharmaceutical University Joint Research Center, 4-23-15 Koutoubashi, Sumida-Ku, Tokyo, 130-8575, Japan. .
Hikita E; Department of Pharmacy, Tokyo Metropolitan Bokutoh Hospital, 4-23-15 Koutoubashi, Sumida-Ku, Tokyo, 130-8575, Japan.
Gando Y; Department of Medicinal Therapy Research, Pharmaceutical Education and Research Center, Meiji Pharmaceutical University, 2-522-1, Noshio, Kiyose, Tokyo, 204-8588, Japan.
Odate M; Department of Molecular Pharmaceutics, Meiji Pharmaceutical University, 2-522-1, Noshio, Kiyose, Tokyo, 204-8588, Japan.
Inoue M; Department of Molecular Pharmaceutics, Meiji Pharmaceutical University, 2-522-1, Noshio, Kiyose, Tokyo, 204-8588, Japan.
Shirota M; Department of Pharmacy, Tokyo Metropolitan Bokutoh Hospital, 4-23-15 Koutoubashi, Sumida-Ku, Tokyo, 130-8575, Japan.; Bokutoh Hospital-Meiji Pharmaceutical University Joint Research Center, 4-23-15 Koutoubashi, Sumida-Ku, Tokyo, 130-8575, Japan.
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Źródło:
Annals of hematology [Ann Hematol] 2023 Jan; Vol. 102 (1), pp. 219-220. Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Letter
MeSH Terms:
Bridged Bicyclo Compounds, Heterocyclic*
Sulfonamides*
Humans ; Solubility ; Tablets
Opinia redakcyjna
Szczegóły
Tytuł:
Design, Synthesis, and Biological Evaluation of Novel 1,4-Pentadien-3-one Derivatives Containing a Sulfonamide Moiety.
Autorzy:
Zhou Q; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang, Guizhou 550025, People's Republic of China.
Zhou Y; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang, Guizhou 550025, People's Republic of China.
Zhu Y; School of Chemical Engineering, Guizhou Institute of Technology, Guiyang, Guizhou 550001, People's Republic of China.
Gong C; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang, Guizhou 550025, People's Republic of China.
Wu Y; Institute of Agro-bioengineering/College of Life Sciences, Guizhou University, Guiyang, Guizhou 550025, People's Republic of China.
Xue W; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang, Guizhou 550025, People's Republic of China.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2022 Dec 28; Vol. 70 (51), pp. 16096-16105. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Sulfonamides*/pharmacology
Structure-Activity Relationship ; Microbial Sensitivity Tests ; Strobilurins ; Sulfanilamide ; Drug Design
Czasopismo naukowe
Szczegóły
Tytuł:
Recent advances in the development of celecoxib analogs as anticancer agents: A review.
Autorzy:
Abdelhaleem EF; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Kassab AE; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
El-Nassan HB; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Khalil OM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2022 Dec; Vol. 355 (12), pp. e2200326. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Sulfonamides*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Celecoxib/pharmacology ; Pyrazoles/pharmacology ; Structure-Activity Relationship ; Cyclooxygenase 2 Inhibitors/pharmacology ; Cyclooxygenase 2 ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Synthesis of hierarchical porous zirconium dioxide and its application in the detection of sulfonamides in animal-derived food.
Autorzy:
Luan X; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Nie W; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Tian X; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Xu J; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Fang W; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Liu S; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Lan X; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Jia W; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Liu Y; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
Liu Z; College of Chemistry and Chemical Engineering, Yantai University, Yantai, China. .
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Źródło:
Analytical methods : advancing methods and applications [Anal Methods] 2022 Dec 01; Vol. 14 (46), pp. 4893-4902. Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sulfonamides*
Polyethylene Glycols*
Animals ; Porosity ; Spectroscopy, Fourier Transform Infrared ; Sulfanilamide ; Lipids
Czasopismo naukowe
Szczegóły
Tytuł:
Selective inhibition of carbonic anhydrase IX by sulphonylated 1,2,3-triazole incorporated benzenesulphonamides capable of inducing apoptosis.
Autorzy:
Siwach K; Department of Chemistry, Kurukshetra University, Kurukshetra, India.
Kumar A; Department of Chemistry, Kurukshetra University, Kurukshetra, India.
Panchal H; Reproductive Physiology Laboratory, Department of Zoology, Kurukshetra University, Kurukshetra, India.
Kumar R; Department of Chemistry, Ch. Mani Ram Godara Government College for Women, Bhodia Khera, Fatehabad, India.
Bhardwaj JK; Reproductive Physiology Laboratory, Department of Zoology, Kurukshetra University, Kurukshetra, India.
Angeli A; Department of Neurosciences, Psychology, Drug Research and Child Health, Pharmaceutical and Nutraceutical Section, University of Florence, Florence, Italy.
Supuran CT; Department of Neurosciences, Psychology, Drug Research and Child Health, Pharmaceutical and Nutraceutical Section, University of Florence, Florence, Italy.
Sharma PK; Department of Chemistry, Kurukshetra University, Kurukshetra, India.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1454-1463.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfonamides*/pharmacology
Triazoles*/pharmacology
Antigens, Neoplasm ; Apoptosis ; Carbonic Anhydrase I/metabolism ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/pharmacology ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Venetoclax-based combinations for acute myeloid leukemia: optimizing their use in Latin-America.
Autorzy:
Gómez-De León A; Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario 'Dr. José Eleuterio González', Monterrey, Mexico.
Demichelis-Gómez R; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, CDMX, Mexico.
Pinedo-Rodríguez A; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, CDMX, Mexico.
Enriquez-Vera D; Universidad Privada San Juan Bautista, Lima, Perú.; Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú.
Flores-Jiménez JA; Centro Universitario de Tonalá, Universidad de Guadalajara, Tonalá, Mexico.
Ceballos-López AA; Clínica de Mérida, Mérida, México.
Rodríguez-Mejorada M; Clínica de Mérida, Mérida, México.
Herrera Riojas MA; Centro Hematológico HOPE, San Luis Potosí, México.
Ovilla-Martínez R; Hospital Ángeles Lomas, Ciudad de México, CDMX, Mexico.
Báez-Islas P; Hospital Ángeles Lomas, Ciudad de México, CDMX, Mexico.
Cota-Rangel X; Hospital Ángeles Lomas, Ciudad de México, CDMX, Mexico.
Neme-Yunes Y; Centro Médico ABC, Ciudad de México, CDMX, Mexico.
Inclán-Alarcón S; Centro Médico ABC, Ciudad de México, CDMX, Mexico.
López-Flores NJ; Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario 'Dr. José Eleuterio González', Monterrey, Mexico.
Colunga-Pedraza PR; Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario 'Dr. José Eleuterio González', Monterrey, Mexico.
Rodríguez-Zúñiga AC; Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario 'Dr. José Eleuterio González', Monterrey, Mexico.
Gómez-Almaguer D; Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario 'Dr. José Eleuterio González', Monterrey, Mexico.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2022 Dec; Vol. 27 (1), pp. 249-257.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Bridged Bicyclo Compounds, Heterocyclic/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Sulfonamides/*therapeutic use
Adult ; Antineoplastic Agents/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Female ; Humans ; Latin America ; Male ; Middle Aged ; Sulfonamides/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of conventional and dispersive solid phase extraction clean-up approaches for the simultaneous analysis of tetracyclines and sulfonamides in a variety of fresh vegetables.
Autorzy:
Vergara-Luis I; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain; Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), Plentzia, Basque Country, Spain. Electronic address: .
Báez-Millán JC; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain.
Baciero I; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain.
González-Gaya B; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain; Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), Plentzia, Basque Country, Spain.
Olivares M; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain; Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), Plentzia, Basque Country, Spain.
Zuloaga O; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain; Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), Plentzia, Basque Country, Spain.
Prieto A; Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Basque Country, Spain; Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), Plentzia, Basque Country, Spain. Electronic address: .
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Źródło:
Talanta [Talanta] 2023 Mar 01; Vol. 254, pp. 124192. Date of Electronic Publication: 2022 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
Vegetables*
Sulfonamides*/analysis
Humans ; Tetracyclines/analysis ; Anti-Bacterial Agents/analysis ; Sulfanilamide/analysis ; Lettuce ; Onions ; Solid Phase Extraction/methods ; Chromatography, High Pressure Liquid/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases.
Autorzy:
Abdoli M; Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, P. Valdenaiela 3, LV-1048 Riga, Latvia.
De Luca V; Department of Biology, Agriculture and Food Sciences, Institute of Biosciences and Bioresources, Via Pietro Castellino 111, 80131 Napoli, Italy.
Capasso C; Department of Biology, Agriculture and Food Sciences, Institute of Biosciences and Bioresources, Via Pietro Castellino 111, 80131 Napoli, Italy.
Supuran CT; NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Florence, Italy.
Žalubovskis R; Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, P. Valdenaiela 3, LV-1048 Riga, Latvia.; Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006 Riga, Latvia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 15; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Carbonic Anhydrase Inhibitors*/pharmacology
Carbonic Anhydrases*/metabolism
Hydantoins*/chemistry
Hydantoins*/pharmacology
Sulfonamides*/chemistry
Sulfonamides*/pharmacology
Humans ; Structure-Activity Relationship ; Benzene Derivatives/chemistry ; Benzene Derivatives/pharmacology ; Eukaryotic Cells/enzymology ; Eukaryotic Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Eco-friendly methods of synthesis and preliminary biological evaluation of sulfonamide derivatives of cyclic arylguanidines.
Autorzy:
Zaręba P; Faculty of Chemical Engineering and Technology, Department of Chemical Technology and Environmental Analytics, Cracow University of Technology, 24 Warszawska Street, 31-155 Cracow, Poland. Electronic address: .
Drabczyk AK; Faculty of Chemical Engineering and Technology, Department of Organic Chemistry and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Cracow, Poland.
Wnorowski A; Department of Biopharmacy, Faculty of Pharmacy, Medical University, Lublin, Poland.
Pindelska E; Department of Analytical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha, 02-093 Warsaw, Poland.
Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Cracow, Poland.
Jaśkowska J; Faculty of Chemical Engineering and Technology, Department of Organic Chemistry and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Cracow, Poland.
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Źródło:
Ultrasonics sonochemistry [Ultrason Sonochem] 2022 Nov; Vol. 90, pp. 106165. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Sulfonamides*/pharmacology
Sulfonamides*/chemistry
Antineoplastic Agents*/chemistry
Humans ; Cell Survival ; Sulfanilamide/pharmacology ; Doxorubicin/pharmacology ; Structure-Activity Relationship ; Cell Line, Tumor ; Molecular Structure
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 37740

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