Temat: "Sulfonamides" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Effectiveness and safety of baricitinib in patients with moderate-to-severe refractory alopecia areata in real world: An open-label, single-center study.
Autorzy:: Bi L; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wang C; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Du Y; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Su T; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Department of Dermatology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Zhao M; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lin X; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Fan W; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Sun W; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Pokaż więcej
Źródło:: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Apr; Vol. 23 (4), pp. 1417-1421. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:: Journal Article
MeSH Terms:: Alopecia Areata*/drug therapy
Janus Kinase Inhibitors*/adverse effects
Azetidines*
Purines*
Pyrazoles*
Sulfonamides*
Male ; Female ; Humans ; Retrospective Studies ; Immunoglobulin A/therapeutic use
SCR Disease Name:: Diffuse alopecia

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Skocz do pozycji: 2.

Tytuł:: Wnt5a/β-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in neovascular age-related macular degeneration.
Autorzy:: Liu D; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China.
Du J; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China.
Xie H; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China.
Tian H; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China.
Lu L; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China.
Zhang C; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China. .
Xu GT; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China. .
Zhang J; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 26; Vol. 21 (1), pp. 75. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:: Journal Article
MeSH Terms:: beta Catenin*/metabolism
Macular Degeneration*/metabolism
Sulfonamides*
Humans ; Male ; Animals ; Mice ; Wnt-5a Protein ; Mice, Inbred C57BL ; Retinal Pigment Epithelium/metabolism ; Epithelial-Mesenchymal Transition ; Fibrosis ; RNA, Small Interfering/metabolism

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Skocz do pozycji: 3.

Tytuł:: IRF1 Mediates Growth Arrest and the Induction of a Secretory Phenotype in Alveolar Epithelial Cells in Response to Inflammatory Cytokines IFNγ/TNFα.
Autorzy:: Recchia Luciani G; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Barilli A; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Visigalli R; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Sala R; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Dall'Asta V; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Rotoli BM; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:: Journal Article
MeSH Terms:: Azetidines*
Cytokines*/metabolism
Purines*
Pyrazoles*
Sulfonamides*
Tumor Necrosis Factor-alpha*/metabolism
Alveolar Epithelial Cells/metabolism ; Cellular Senescence ; Interleukin-6/metabolism ; Phenotype ; A549 Cells ; Humans

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Skocz do pozycji: 4.

Tytuł:: PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer.
Autorzy:: Khan S; Department of Biochemistry & Structural Biology, Long School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Cao L; Department of Biochemistry & Structural Biology, Long School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Wiegand J; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Zhang P; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Zajac-Kaye M; Department of Anatomy & Cell Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Kaye FJ; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Zheng G; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Zhou D; Department of Biochemistry & Structural Biology, Long School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 17; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:: Journal Article
MeSH Terms:: Lung Neoplasms*/drug therapy
Small Cell Lung Carcinoma*/pathology
Antineoplastic Agents*/pharmacology
Thrombocytopenia*
Aniline Compounds*
Sulfonamides*
Bridged Bicyclo Compounds, Heterocyclic*
Humans ; Mice ; Animals ; bcl-X Protein/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Disease Models, Animal

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Skocz do pozycji: 5.

Tytuł:: Steroid-Induced Ocular Hypertension in Mice Is Differentially Reduced by Selective EP2, EP3, EP4, and IP Prostanoid Receptor Agonists.
Autorzy:: Sharif NA; Ophthalmology Innovation Center, Santen Inc., Emeryville, CA 94608, USA.; Institute of Ophthalmology, University College London (UCL), London EC1V 9EL, UK.; Department of Ophthalmology, Imperial College of Science and Technology, St. Mary's Campus, London W2 1PG, UK.; Department of Ophthalmology, Eye-ACP Duke-National University of Singapore Medical School, Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 168751, Singapore.; Department of Pharmacy Sciences, Creighton University, Omaha, NE 68178, USA.; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA.; Department of Pharmacology & Neuroscience, North Texas Eye Research Institute (NTERI), University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
Millar JC; Department of Pharmacology & Neuroscience, North Texas Eye Research Institute (NTERI), University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
Zode G; Department of Ophthalmology and Center for Translational Vision Research, University of California, Irvine, CA 92617, USA.
Ota T; Ophthalmology Innovation Center, Santen Pharmaceutical Co., Ltd., Nara 630-0101, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 15; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Misoprostol*/pharmacology
Misoprostol*/therapeutic use
Ocular Hypertension*/chemically induced
Ocular Hypertension*/drug therapy
Acetamides*
Acetates*
Pyrazines*
Sulfonamides*
Animals ; Mice ; Tissue Plasminogen Activator ; Receptors, Prostaglandin ; Receptors, Prostaglandin E, EP4 Subtype ; Steroids

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Skocz do pozycji: 6.

Tytuł:: Comparison of vonoprazan and proton pump inhibitors for the treatment of gastric endoscopic submucosal dissection-induced ulcer: an updated systematic review and meta-analysis.
Autorzy:: Chen L; Department of Infectious Disease, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong, China.
Jiang D; Department of Gastroenterology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong, China.
Hu D; Department of Gastroenterology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong, China.
Cui X; Department of Gastroenterology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong, China. .; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2024 Mar 15; Vol. 24 (1), pp. 110. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:: Stomach Ulcer*/drug therapy
Stomach Ulcer*/etiology
Stomach Ulcer*/surgery
Endoscopic Mucosal Resection*/adverse effects
Endoscopic Mucosal Resection*/methods
Stomach Neoplasms*/surgery
Pyrroles*
Sulfonamides*
Humans ; Proton Pump Inhibitors/therapeutic use ; Ulcer/drug therapy ; Ulcer/etiology ; Postoperative Hemorrhage ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 7.

Tytuł:: Rare Case of Recurrent Adamantinoma of the Tibia: Limited Efficacy of Pazopanib as a Standalone Treatment.
Autorzy:: Elshenawy M; Department of Medical Oncology, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.; Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Menoufia University, Shebin El Kom, Egypt.
Aldahoul SK; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
El-Sibai AM; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Hamad A; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Arabi TZ; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Abdul Rab S; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Badran A; Department of Medical Oncology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Alzaid T; Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Sabbah BN; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Atallah JP; Department of Medical Oncology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Pokaż więcej
Źródło:: The American journal of case reports [Am J Case Rep] 2024 Mar 15; Vol. 25, pp. e941248. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Adamantinoma*/pathology
Adamantinoma*/secondary
Adamantinoma*/surgery
Bone Neoplasms*/pathology
Ameloblastoma*/complications
Ameloblastoma*/pathology
Ameloblastoma*/surgery
Indazoles*
Pyrimidines*
Sulfonamides*
Female ; Humans ; Young Adult ; Adult ; Tibia/surgery

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Skocz do pozycji: 8.

Tytuł:: C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription.
Autorzy:: Du M; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Wang M; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Liu M; Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, USA.
Fu S; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.
Lin Y; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Huo Y; Hematology Department, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Rd., Zhengzhou, 450000, Henan Province, People's Republic of China.
Yu J; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China.; Institute of Hematology, Zhejiang University, Hangzhou, China.
Yu X; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China.
Wang C; Hematology Department, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Rd., Zhengzhou, 450000, Henan Province, People's Republic of China. .
Xiao H; Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. .; Institute of Hematology, Zhejiang University, Hangzhou, China. .; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China. .
Wang L; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Rd., Hangzhou, 310003, Zhejiang Province, People's Republic of China. .; Institute of Hematology, Zhejiang University, Hangzhou, China. .; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Mar 13; Vol. 43 (1), pp. 79. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/therapeutic use
Bridged Bicyclo Compounds, Heterocyclic*
Leukemia, Myeloid, Acute*/metabolism
Sulfonamides*
Animals ; Humans ; Mice ; CCAAT-Enhancer-Binding Protein-alpha/genetics ; CCAAT-Enhancer-Binding Protein-alpha/metabolism ; CCAAT-Enhancer-Binding Protein-alpha/therapeutic use ; Protein Isoforms ; Proto-Oncogene Proteins c-bcl-2/genetics ; Transcription Factor CHOP/genetics ; Unfolded Protein Response

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Skocz do pozycji: 9.

Tytuł:: Ripasudil as a Potential Therapeutic Agent in Treating Secondary Glaucoma in HTLV-1-Uveitis: An In Vitro Analysis.
Autorzy:: Yang M; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Kamoi K; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Zong Y; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Zhang J; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Zou Y; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Ohno-Matsui K; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 12; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:: Journal Article
MeSH Terms:: Human T-lymphotropic virus 1*
Glaucoma*/drug therapy
Glaucoma*/etiology
Uveitis*
Isoquinolines*
Sulfonamides*
Adult ; Humans ; NF-kappa B ; Cytokines/therapeutic use ; Interleukin-6 ; rho-Associated Kinases

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Skocz do pozycji: 10.

Tytuł:: Electrolyte disorders induced by six multikinase inhibitors therapy for renal cell carcinoma: a large-scale pharmacovigilance analysis.
Autorzy:: She X; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Yin D; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Guo Q; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Tang Y; Department of Pharmacy, School of Pharmacy, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Wang S; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China. .
Wang X; Central Laboratory, Shanxi Hospital of Integrated Traditional Chinese and Western Medicine, Taiyuan, Shanxi, People's Republic of China. .; Key Laboratory of Research and Development of Traditional Chinese Medicine Preparations, Taiyuan, Shanxi, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5592. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:: Journal Article; Observational Study
MeSH Terms:: Anilides*
Carcinoma, Renal Cell*/drug therapy
Indazoles*
Kidney Neoplasms*/pathology
Phenylurea Compounds*
Pyridines*
Pyrimidines*
Quinolines*
Sulfonamides*
Aged ; Humans ; Male ; Axitinib/therapeutic use ; Bayes Theorem ; Electrolytes ; Pharmacovigilance ; Retrospective Studies ; Sorafenib/adverse effects ; Sunitinib/adverse effects ; United States ; United States Food and Drug Administration ; Female ; Middle Aged

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Skocz do pozycji: 11.

Tytuł:: Intracerebral hemorrhage-induced brain injury in mice: The role of peroxiredoxin 2-Toll-like receptor 4 inflammatory axis.
Autorzy:: Du Y; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Wang J; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Zhang J; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Li N; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Li G; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Liu X; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Lin Y; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Wang D; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Kang K; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Bian L; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.
Zhao X; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.; Research Unit of Artificial Intelligence in Cerebrovascular Disease, Chinese Academy of Medical Sciences, Beijing, China.; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14681.
Typ publikacji:: Journal Article
MeSH Terms:: Brain Injuries*/etiology
Sulfonamides*
Toll-Like Receptor 4*/metabolism
Animals ; Mice ; Cerebral Hemorrhage/metabolism ; Inflammation/etiology ; Inflammation/pathology ; Mice, Inbred C57BL ; Peroxiredoxins/metabolism ; Peroxiredoxins/pharmacology ; Peroxiredoxins/therapeutic use

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Skocz do pozycji: 12.

Tytuł:: A systematic review of case series and clinical trials investigating systemic oral or injectable therapies for the treatment of vitiligo.
Autorzy:: Jafarzadeh A; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Pour Mohammad A; Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Khosravi M; Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Amiri S; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Rasouli A; School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Keramati H; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Goodarzi A; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.; Pokaż więcej
Źródło:: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2024 Mar; Vol. 30 (3), pp. e13642.
Typ publikacji:: Systematic Review; Journal Article; Review
MeSH Terms:: Vitiligo*/drug therapy
Vitiligo*/pathology
Hypopigmentation*
Purines*
Pyrazoles*
Sulfonamides*
Azetidines*
Thalidomide/*analogs & derivatives
Humans ; Methotrexate/therapeutic use ; Azathioprine/therapeutic use ; Mycophenolic Acid/therapeutic use ; Minocycline/therapeutic use ; Alefacept/therapeutic use ; Cyclosporine/therapeutic use ; Adrenal Cortex Hormones ; Simvastatin/therapeutic use ; Zinc/therapeutic use

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Skocz do pozycji: 13.

Tytuł:: Venetoclax efficacy on acute myeloid leukemia is enhanced by the combination with butyrate.
Autorzy:: Kawakatsu R; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Tadagaki K; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Yamasaki K; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Yoshida T; Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 29; Vol. 14 (1), pp. 4975. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article
MeSH Terms:: Butyrates*/pharmacology
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/metabolism
Sulfonamides*
Humans ; Cell Line, Tumor ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Apoptosis ; Caspases

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Skocz do pozycji: 14.

Tytuł:: Inhibition of Toll-like Receptor 4 Using Small Molecule, TAK-242, Protects Islets from Innate Immune Responses.
Autorzy:: Mattke J; Institute of Biomedical Studies, Baylor University, Waco, TX 76706, USA.
Darden CM; Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX 75204, USA.
Vasu S; Islet Cell Laboratory, Baylor Scott and White Research Institute, Dallas, TX 75204, USA.
Lawrence MC; Islet Cell Laboratory, Baylor Scott and White Research Institute, Dallas, TX 75204, USA.
Kirkland J; Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX 75204, USA.
Kane RR; Institute of Biomedical Studies, Baylor University, Waco, TX 76706, USA.
Naziruddin B; Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX 75204, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Feb 27; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Immunity, Innate*/drug effects
Islets of Langerhans Transplantation*/methods
MicroRNAs*
Sulfonamides*/pharmacology
Toll-Like Receptor 4*/antagonists & inhibitors
Islets of Langerhans*/drug effects
Islets of Langerhans*/immunology
Humans

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Skocz do pozycji: 15.

Tytuł:: Splicing targeting drugs highlight intron retention as an actionable vulnerability in advanced prostate cancer.
Autorzy:: Naro C; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168, Rome, Italy.; GSTeP Organoids Research Core Facility, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168, Rome, Italy.
Antonioni A; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168, Rome, Italy.
Medici V; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168, Rome, Italy.
Caggiano C; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168, Rome, Italy.; GSTeP Organoids Research Core Facility, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168, Rome, Italy.
Jolly A; GenoSplice, Paris, France.
de la Grange P; GenoSplice, Paris, France.
Bielli P; Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133, Rome, Italy.
Paronetto MP; Laboratory of Molecular and Cellular Neurobiology, IRCCS Fondazione Santa Lucia, 00143, Rome, Italy.; University of Rome Foro Italico, 00135, Rome, Italy.
Sette C; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168, Rome, Italy. .; GSTeP Organoids Research Core Facility, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168, Rome, Italy. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 27; Vol. 43 (1), pp. 58. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Alternative Splicing*
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Sulfonamides*
Macrolides*
Anilides*
Epoxy Compounds*
Pyrimidines*
Male ; Humans ; Introns ; Androgen Antagonists ; Androgens ; RNA Splicing ; Proto-Oncogene Proteins/genetics ; Cell Cycle Proteins/genetics

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Skocz do pozycji: 16.

Tytuł:: Can the combination of antiplatelet or alteplase thrombolytic therapy with argatroban benefit patients suffering from acute stroke? a systematic review, meta-analysis, and meta-regression.
Autorzy:: Xie H; Department of Clinical Pharmacy, The Third Hospital of Quzhou, Quzhou, Zhejiang, 324003, China.
Chen Y; Hangzhou Fuyang District Hospital of Traditional Chinese Medicine, Zhejiang, 311499, China.
Ge W; Department of Clinical Pharmacy, Ninghai First Hospital, Zhejiang, 315600, China.
Xu X; Department of Emergency Internal Medicine, The Third Hospital of Quzhou, Quzhou, Zhejiang, 324003,China.
Liu C; Department of General Medicine, Affiliated Anqing First People's Hospital of Anhui Medical University, HeFei, 246000, China.
Lan Z; Department of Psychiatry Department, The Third Hospital of Quzhou, Quzhou, Zhejiang, 324003, China.
Yang Y; Department of Neurology, Ninghai First Hospital, Zhejiang, 315600, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 27; Vol. 19 (2), pp. e0298226. Date of Electronic Publication: 2024 Feb 27 (Print Publication: 2024).
Typ publikacji:: Systematic Review; Meta-Analysis; Journal Article
MeSH Terms:: Platelet Aggregation Inhibitors*/therapeutic use
Stroke*/complications
Stroke*/drug therapy
Stroke*/chemically induced
Pipecolic Acids*
Sulfonamides*
Arginine/*analogs & derivatives
Humans ; Tissue Plasminogen Activator/therapeutic use ; Retrospective Studies ; Hemorrhage/drug therapy ; Hemorrhage/chemically induced ; Fibrinolytic Agents/therapeutic use ; Thrombolytic Therapy ; Treatment Outcome ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 17.

Tytuł:: Serum microRNA profile of rhesus macaques following ionizing radiation exposure and treatment with a medical countermeasure, Ex-Rad.
Autorzy:: Russ E; Division of Radioprotectants, Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20817, USA.; Graduate Program of Cellular and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Fatanmi OO; Division of Radioprotectants, Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Wise SY; Division of Radioprotectants, Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Carpenter AD; Division of Radioprotectants, Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Maniar M; Onconova Therapeutics, Inc., Newtown, PA, 18940, USA.; Palm Pharmaceuticals, Inc, 46750 Sentinel Drive, Fremont, CA, 94539, USA.
Iordanskiy S; Division of Radioprotectants, Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .
Singh VK; Division of Radioprotectants, Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, 4301 Jones Bridge Road, Bethesda, MD, 20814-2712, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 24; Vol. 14 (1), pp. 4518. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:: Journal Article
MeSH Terms:: Medical Countermeasures*
MicroRNAs*/genetics
Radiation Exposure*/analysis
Acute Radiation Syndrome*
Sulfonamides*
Animals ; Macaca mulatta/genetics ; Radiation, Ionizing

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Skocz do pozycji: 18.

Tytuł:: [Effect of venetoclax plus chemotherapy on treatment-naive acute myeloid leukemia patients with moderate to poor cytogenetic profiles and the combination's influence on the expression of proteins of the anti-apoptoic family].
Źródło:: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2024 Feb 23; Vol. 46 (2), pp. 161-167.
Typ publikacji:: English Abstract; Journal Article; Observational Study; Randomized Controlled Trial
MeSH Terms:: Bridged Bicyclo Compounds, Heterocyclic*
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Sulfonamides*
Adult ; Humans ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cytarabine/therapeutic use ; Cytogenetic Analysis ; Myeloid Cell Leukemia Sequence 1 Protein/therapeutic use ; Retrospective Studies

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Skocz do pozycji: 19.

Tytuł:: Comparative efficacy and safety of Sofosbuvir/Velpatasvir and Danoprevir for the treatment of chronic hepatitis C: the real-world data in China.
Autorzy:: Zhou Y; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.
Liang M; Department of Infectious disease, The First people's hospital of Foshan, Foshan City, Guangdong Province, China.
Li Y; Department of General Practice, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou City, Guangdong Province, China.
Chen X; Department of Infectious Diseases, Yangjiang Public Health Hospital, Yangjiang City, Guangdong Province, China.
Yang J; Clinical Medicine Department of Southwest Medical University, Luzhou City, Sichuan Province, China.
Bai H; Department of Infectious disease, The First people's hospital of Foshan, Foshan City, Guangdong Province, China.
Long Y; Department of Infectious Diseases, The Eighth Hospital of Guangzhou Medical University, Guangzhou City, Guangdong Province, China.
Zhang X; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China.
Lin C; Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road , 510630, Guangzhou City, Guangdong Province, China. .; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2024 Feb 14; Vol. 24 (1), pp. 73. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Benzimidazoles*
Benzopyrans*
Carbamates*
Cyclopropanes*
Drug Combinations*
Hepatitis C*/drug therapy
Hepatitis C, Chronic*/genetics
Isoindoles*
Lactams, Macrocyclic*
Proline*/analogs & derivatives
Sulfonamides*
Humans ; Antiviral Agents/adverse effects ; China ; Genotype ; Hepacivirus/genetics ; Heterocyclic Compounds, 4 or More Rings/adverse effects ; Liver Cirrhosis/drug therapy ; Retrospective Studies ; Ribavirin/adverse effects ; Sofosbuvir/adverse effects ; Treatment Outcome

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Skocz do pozycji: 20.

Tytuł:: Senolytic treatment alleviates doxorubicin-induced chemobrain.
Autorzy:: Budamagunta V; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.; Genetics and Genomics Graduate Program, Genetics Institute, University of Florida, Gainesville, Florida, USA.; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Kumar A; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.
Rani A; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.
Manohar Sindhu S; Genetics and Genomics Graduate Program, Genetics Institute, University of Florida, Gainesville, Florida, USA.
Yang Y; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
Zhou D; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida, USA.; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Foster TC; Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA.; Genetics and Genomics Graduate Program, Genetics Institute, University of Florida, Gainesville, Florida, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Feb; Vol. 23 (2), pp. e14037. Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:: Journal Article
MeSH Terms:: Chemotherapy-Related Cognitive Impairment*
Sulfonamides*
Humans ; Senotherapeutics ; Doxorubicin/adverse effects ; Aniline Compounds ; Cellular Senescence

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