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Tytuł:
Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice.
Autorzy:
Sun X; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Liu S; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Cai J; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Yang M; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Li C; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Tan M; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
He B; Key Laboratory of Animal Physiology & Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; MOE Joint International Research Laboratory of Animal Health & Food Safety, Nanjing Agricultural University, Nanjing 210095, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 22; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondria*/genetics
Mitochondria*/metabolism
Inflammation*/genetics
Inflammation*/metabolism
Animals ; Mice ; Mitochondrial Proteins/metabolism ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PEX-168 improves insulin resistance, inflammatory response and adipokines in simple obese mice: a mechanistic exploration.
Autorzy:
Guo Z; College of Nursing, Yangzhou University, Yangzhou, China.
Wu Y; College of Nursing, Yangzhou University, Yangzhou, China.
Zhu L; Northern Jiangsu People's Hospital, Yangzhou, China.
Wang Y; General Surgery Institute of Yangzhou, Yangzhou University, Yangzhou, China.
Wang D; Northern Jiangsu People's Hospital, Yangzhou, China.; General Surgery Institute of Yangzhou, Yangzhou University, Yangzhou, China.; Clinical Medical College of Yangzhou University, Yangzhou, China.
Sun X; College of Nursing, Yangzhou University, Yangzhou, China. .; Northern Jiangsu People's Hospital, Yangzhou, China. .
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Źródło:
BMC endocrine disorders [BMC Endocr Disord] 2021 Dec 20; Vol. 21 (1), pp. 245. Date of Electronic Publication: 2021 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Adipokines/*metabolism
Hyperinsulinism/*drug therapy
Hypoglycemic Agents/*pharmacology
Inflammation/*drug therapy
Obesity/*drug therapy
Peptides/*pharmacology
Polyethylene Glycols/*pharmacology
Animals ; Diet, High-Fat ; Disease Models, Animal ; Hypoglycemic Agents/administration & dosage ; Insulin Resistance/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Peptides/administration & dosage ; Polyethylene Glycols/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway.
Autorzy:
Sun X; Department of Orthopedics, Yantaishan Hospital, Yantai, China.
Li P; Department of Orthopedics and Traumatology, Dezhou Hospital of Traditional Chinese Medicine, Dezhou, China.
Qu X; Clinical Teaching and Research Section, Yantai Nursing School, Yantai, China.
Liu W; Department of Joint Surgery, the Second Hospital of Shandong University, Jinan, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 1326-1333.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Apigenin/*pharmacology
Arthritis, Gouty/*drug therapy
Inflammation/*drug therapy
Animals ; Antioxidants/pharmacology ; Arthritis, Gouty/pathology ; Colchicine/pharmacology ; Disease Models, Animal ; Inflammation/pathology ; Male ; Myeloid Differentiation Factor 88/metabolism ; NF-kappa B/metabolism ; Rats ; Rats, Sprague-Dawley ; Sulfonamides/pharmacology ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Coniferyl Aldehyde Inhibits the Inflammatory Effects of Leptomeningeal Cells by Suppressing the JAK2 Signaling.
Autorzy:
Wang Y; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Gao Y; VIP Integrated Department, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Li X; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Sun X; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Wang Z; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Wang H; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Nie R; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Yu W; Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
Zhou Y; Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Sep 14; Vol. 2020, pp. 4616308. Date of Electronic Publication: 2020 Sep 14 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Acrolein/*analogs & derivatives
Anti-Inflammatory Agents/*pharmacology
Inflammation/*drug therapy
Janus Kinase 2/*metabolism
Meninges/*drug effects
Acrolein/pharmacology ; Animals ; Cell Line ; Cytokines/metabolism ; Inflammation/metabolism ; Macrophages/drug effects ; Macrophages/metabolism ; Meninges/metabolism ; Mice ; Mice, Inbred C57BL ; Microglia/drug effects ; Microglia/metabolism ; RAW 264.7 Cells ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gastrodiae Rhizoma Water Extract Ameliorates Hypothalamic-Pituitary-Adrenal Axis Hyperactivity and Inflammation Induced by Chronic Unpredictable Mild Stress in Rats.
Autorzy:
Wang M; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
Dong W; Harbin University of Commerce, Harbin, 150076 Heilongjiang, China.
Wang R; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
Xu X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
Wu Y; Department of Traditional Chinese Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.
Sun G; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
Sun X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Jun 10; Vol. 2020, pp. 8374614. Date of Electronic Publication: 2020 Jun 10 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal/*pharmacology
Hypothalamo-Hypophyseal System/*drug effects
Inflammation/*metabolism
Pituitary-Adrenal System/*drug effects
Stress, Psychological/*metabolism
Animals ; Behavior, Animal/drug effects ; Chronic Disease ; Cytokines/metabolism ; Disease Models, Animal ; Gastrodia/chemistry ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modulation of inflammatory factors predicts the outcome following spinal cord injury.
Autorzy:
Yu Z; Department of Intervention, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, People's Republic of China.
Sun X; Department of Intervention, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, People's Republic of China.
Xia R; Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, People's Republic of China.
Chen Q; Department of Oncology, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215008, People's Republic of China.
Wu Q; Department of Ultrasonography, Suzhou Science and Technology Town Hospital, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215001, People's Republic of China. .
Zheng W; Department of Orthopaedics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215008, People's Republic of China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2020 Jun 01; Vol. 15 (1), pp. 199. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation/*blood
Interleukin-10/*blood
Interleukin-4/*blood
Spinal Cord Injuries/*diagnosis
Animals ; Biomarkers/blood ; Histocompatibility Antigens Class I/blood ; Inflammation/diagnosis ; Inflammation/pathology ; Male ; Prognosis ; Rats ; Rats, Sprague-Dawley ; Spinal Cord Injuries/blood ; Spinal Cord Injuries/pathology ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
TFEB-NF-κB inflammatory signaling axis: a novel therapeutic pathway of Dihydrotanshinone I in doxorubicin-induced cardiotoxicity.
Autorzy:
Wang X; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Wang Q; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Li W; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Zhang Q; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Jiang Y; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Guo D; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Sun X; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Lu W; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Li C; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China. .
Wang Y; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China. doctor_.; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. doctor_.
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2020 May 24; Vol. 39 (1), pp. 93. Date of Electronic Publication: 2020 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antibiotics, Antineoplastic/*toxicity
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*metabolism
Cardiotoxicity/*drug therapy
Doxorubicin/*toxicity
Inflammation/*prevention & control
NF-kappa B/*metabolism
Phenanthrenes/*pharmacology
Animals ; Apoptosis ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Cardiotoxicity/etiology ; Cardiotoxicity/metabolism ; Cardiotoxicity/pathology ; Cell Proliferation ; Cells, Cultured ; Cytokines/metabolism ; Furans ; Gene Expression Regulation ; Humans ; Inflammation/etiology ; Inflammation/metabolism ; Inflammation/pathology ; Macrophages/drug effects ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; NF-kappa B/genetics ; Phosphorylation ; Quinones ; Zebrafish
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effects of Leukocyte-Platelet Rich Fibrin (L-PRF) on Suppression of the Expressions of the Pro-Inflammatory Cytokines, and Proliferation of Schwann Cell, and Neurotrophic Factors.
Autorzy:
Wang Z; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China.
Mudalal M; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China.; Department of Oral and Maxillofacial Surgery and Periodontology, Faculty of Dentistry, The Arab American University, Jenin, 240, Palestine.
Sun Y; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China.
Liu Y; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China.
Wang J; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China.
Wang Y; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China.
Sun X; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China. .; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China. .
Zhou Y; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China. .; Provincial Key Laboratory of Dental Development, Jaw Remodeling and Regeneration, Jilin University, Changchun, 130021, China. .
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Źródło:
Scientific reports [Sci Rep] 2020 Feb 12; Vol. 10 (1), pp. 2421. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nerve Regeneration*
Cytokines/*metabolism
Inflammation/*therapy
Nerve Growth Factors/*metabolism
Platelet-Rich Fibrin/*metabolism
Schwann Cells/*cytology
Animals ; Cell Proliferation ; Cytokines/analysis ; Inflammation/metabolism ; Nerve Growth Factors/administration & dosage ; Platelet-Rich Fibrin/chemistry ; Rabbits ; Schwann Cells/metabolism ; Tissue Scaffolds/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Astragaloside inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes and ameliorates the progression of osteoarthritis in mice.
Autorzy:
Li H; Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.; Department of Orthopedics, First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.
Peng Y; Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.; Department of Orthopedics, First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.
Wang X; Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.; Department of Internal Medicine, Hanan Branch, Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine , Haerbin , Heilongjiang , China.
Sun X; Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.; Five Department of Acupuncture and Moxibustion, First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.
Yang F; Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.; Department of Orthopedics, Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.
Sun Y; Department of Orthopedics, Haerbin Fifth Hospital , Haerbin , China.
Wang B; Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.; Department of Orthopedics, First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine , Haerbin , China.
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Źródło:
Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2019 Aug; Vol. 41 (4), pp. 497-503. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Chondrocytes/*drug effects
Inflammation/*drug therapy
Interleukin-1beta/*metabolism
Osteoarthritis/*drug therapy
Animals ; Cells, Cultured ; Chondrocytes/metabolism ; Disease Models, Animal ; Humans ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Osteoarthritis/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
Autorzy:
Li T; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yang S; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
She X; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yan Q; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang P; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhu H; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.
Wang F; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.
Luo X; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.
Sun X; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 Mar; Vol. 176 (6), pp. 801-813. Date of Electronic Publication: 2019 Jan 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adrenergic alpha-1 Receptor Antagonists/*pharmacology
Adrenergic beta-2 Receptor Agonists/*pharmacology
Inflammation/*prevention & control
Oxidative Stress/*drug effects
Photoreceptor Cells/*drug effects
Protective Agents/*pharmacology
Receptors, Adrenergic, alpha-1/*metabolism
Signal Transduction/*drug effects
Adrenergic alpha-1 Receptor Antagonists/administration & dosage ; Adrenergic beta-2 Receptor Agonists/administration & dosage ; Animals ; Apoptosis/drug effects ; Disease Models, Animal ; Doxazosin/administration & dosage ; Doxazosin/pharmacology ; Guanabenz/administration & dosage ; Guanabenz/pharmacology ; Hyaluronic Acid/administration & dosage ; Inflammation/chemically induced ; Inflammation/pathology ; Injections, Intraperitoneal ; Male ; Protective Agents/administration & dosage ; Rats ; Rats, Inbred BN
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protective effect of oxytocin on LPS-induced acute lung injury in mice.
Autorzy:
An X; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China.
Sun X; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China.
Hou Y; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China.
Yang X; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China.
Chen H; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China.
Zhang P; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China.
Wu J; Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, P.R. China. .
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Źródło:
Scientific reports [Sci Rep] 2019 Feb 26; Vol. 9 (1), pp. 2836. Date of Electronic Publication: 2019 Feb 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammation*
Acute Lung Injury/*prevention & control
Oxytocin/*therapeutic use
Acute Lung Injury/chemically induced ; Animals ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Cytokines ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred C57BL ; Oxytocin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bone-targeted methotrexate-alendronate conjugate inhibits osteoclastogenesis in vitro and prevents bone loss and inflammation of collagen-induced arthritis in vivo.
Autorzy:
Xie Z; a Department of Orthopaedics , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou , China.; b Key Laboratory of Biotherapy of Zhejiang Province , Hangzhou , China.
Liu G; c School of Chemistry and Chemical Engineering , Yangzhou University , Jiangsu , China.
Tang P; a Department of Orthopaedics , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou , China.; b Key Laboratory of Biotherapy of Zhejiang Province , Hangzhou , China.
Sun X; a Department of Orthopaedics , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou , China.; b Key Laboratory of Biotherapy of Zhejiang Province , Hangzhou , China.
Chen S; a Department of Orthopaedics , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou , China.
Qin A; d Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implant , Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , PR China.
Zhu P; c School of Chemistry and Chemical Engineering , Yangzhou University , Jiangsu , China.
Zhang J; a Department of Orthopaedics , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou , China.
Fan S; a Department of Orthopaedics , Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou , China.
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Źródło:
Drug delivery [Drug Deliv] 2018 Nov; Vol. 25 (1), pp. 187-197.
Typ publikacji:
Journal Article
MeSH Terms:
Alendronate/*pharmacology
Arthritis, Experimental/*drug therapy
Bone Resorption/*prevention & control
Bone and Bones/*drug effects
Inflammation/*drug therapy
Methotrexate/*pharmacology
Osteogenesis/*drug effects
Animals ; Arthritis, Experimental/chemically induced ; Arthritis, Experimental/metabolism ; Arthritis, Rheumatoid/chemically induced ; Arthritis, Rheumatoid/drug therapy ; Bone Resorption/metabolism ; Bone and Bones/metabolism ; Collagen/pharmacology ; Cytokines/metabolism ; Drug Therapy, Combination/methods ; Female ; Inflammation/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Muramidase/metabolism ; Osteoclasts/drug effects ; Osteoclasts/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An inflammation-based cumulative prognostic score system in patients with diffuse large B cell lymphoma in rituximab era.
Autorzy:
Sun F; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.
Zhu J; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.
Lu S; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.
Zhen Z; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.
Wang J; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.
Huang J; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China.
Ding Z; Department of Biochemistry and Molecular Biology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, AZ, 85259, USA.
Zeng M; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China. .
Sun X; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China. .; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, NO.651 of Dongfeng East Road, Guangzhou, 510060, China. .
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Źródło:
BMC cancer [BMC Cancer] 2018 Jan 02; Vol. 18 (1), pp. 5. Date of Electronic Publication: 2018 Jan 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Biomarkers, Tumor/*analysis
Inflammation/*pathology
Lymphocytes/*pathology
Lymphoma, Large B-Cell, Diffuse/*pathology
Monocytes/*pathology
Neutrophils/*pathology
C-Reactive Protein/metabolism ; Cyclophosphamide/administration & dosage ; Doxorubicin/administration & dosage ; Female ; Follow-Up Studies ; Humans ; Inflammation/metabolism ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Male ; Middle Aged ; Prednisone/administration & dosage ; Prognosis ; Retrospective Studies ; Risk Factors ; Rituximab/administration & dosage ; Survival Rate ; Vincristine/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice.
Autorzy:
Li M; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Li C; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Yu H; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Cai X; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Shen X; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Sun X; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Wang J; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Zhang Y; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China.
Wang C; Ningbo Key Laboratory of Behavioral Neuroscience, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China. .; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China. .; Department of Physiology and Pharmacology, Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang, 315211, People's Republic of China. .; Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, Ningbo University, Ningbo, 315211, People's Republic of China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2017 Sep 20; Vol. 14 (1), pp. 190. Date of Electronic Publication: 2017 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Behavior, Animal/*physiology
Hippocampus/*immunology
Hippocampus/*metabolism
Inflammation/*complications
Interleukin-1beta/*metabolism
Animals ; Anxiety/immunology ; Anxiety/metabolism ; Behavior, Animal/drug effects ; Depression/immunology ; Depression/metabolism ; Gene Knockdown Techniques ; Inflammation/chemically induced ; Lentivirus ; Lipopolysaccharides/toxicity ; Male ; Memory Disorders/immunology ; Memory Disorders/metabolism ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Arsenic affects inflammatory cytokine expression in Gallus gallus brain tissues.
Autorzy:
Sun X; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China.
He Y; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China.
Guo Y; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China.
Li S; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China.
Zhao H; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China.
Wang Y; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China.
Zhang J; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China. .
Xing M; College of Wildlife Resources, Northeast Forestry University, Harbin, Heilongjiang Province, 150040, China. .
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Źródło:
BMC veterinary research [BMC Vet Res] 2017 Jun 05; Vol. 13 (1), pp. 157. Date of Electronic Publication: 2017 Jun 05.
Typ publikacji:
Journal Article
MeSH Terms:
Chickens*
Arsenic/*toxicity
Brain/*drug effects
Cytokines/*biosynthesis
Inflammation/*veterinary
Animal Feed ; Animals ; Brain/metabolism ; Brain/ultrastructure ; Inflammation/chemically induced ; Inflammation/metabolism ; Male ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Prostaglandin-E Synthases/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Impact of systemic inflammation on gastric cancer outcomes.
Autorzy:
Liu X; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chen S; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Liu J; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Xu D; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Li W; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhan Y; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Li Y; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chen Y; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhou Z; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Sun X; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; Department of Gastric and Pancreatic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
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Źródło:
PloS one [PLoS One] 2017 Mar 30; Vol. 12 (3), pp. e0174085. Date of Electronic Publication: 2017 Mar 30 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Prognosis*
Biomarkers, Tumor/*blood
Inflammation/*blood
Stomach Neoplasms/*blood
Adult ; Aged ; C-Reactive Protein/metabolism ; Disease-Free Survival ; Female ; Humans ; Inflammation/pathology ; Lymphocyte Count ; Lymphocytes/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Neutrophils/pathology ; Stomach Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Recent Advances of Curcumin in the Prevention and Treatment of Renal Fibrosis.
Autorzy:
Sun X; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Liu Y; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Li C; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Wang X; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Zhu R; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Liu C; Chinese Material Medical School, Beijing University of Chinese Medicine, Beijing 100029, China.
Liu H; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Wang L; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Ma R; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
Fu M; The Research Institute of McGill University Health Center, Montreal, QC, Canada H4A 3J1.
Zhang D; Diabetes Research Center, Beijing University of Chinese Medicine, Beijing 100029, China.
Li Y; Preclinical Medicine School, Beijing University of Chinese Medicine, Beijing 100029, China.
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Źródło:
BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 2418671. Date of Electronic Publication: 2017 May 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Curcumin/*therapeutic use
Fibrosis/*prevention & control
Inflammation/*prevention & control
Kidney Diseases/*prevention & control
Animals ; Fibrosis/diet therapy ; Fibrosis/genetics ; Fibrosis/pathology ; Humans ; Inflammation/diet therapy ; Inflammation/genetics ; Inflammation/pathology ; Interleukin-1beta/genetics ; Kidney/drug effects ; Kidney/pathology ; Kidney Diseases/diet therapy ; Kidney Diseases/genetics ; Kidney Diseases/pathology ; Models, Animal ; NF-kappa B/genetics ; Transforming Growth Factor beta/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of Leukocyte Recruitment to the Spleen and Peritoneal Cavity during Pristane-Induced Inflammation.
Autorzy:
Li Y; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Wu J; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.; Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
Xu L; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.
Wu Q; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.
Wan Z; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Li L; Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
Yu H; Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
Li X; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Li K; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Zhang Q; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
Hou Z; Department of Tuberculosis, Tianjin Haihe Hospital, Tianjin 300350, China.
Sun X; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.; Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Institute of Respiratory Diseases, Tianjin Haihe Hospital, Tianjin 300350, China.
Chen H; Department of Basic Medicine, Haihe Clinical College of Tianjin Medical University, Tianjin, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2017; Vol. 2017, pp. 9891348. Date of Electronic Publication: 2017 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation/*immunology
Macrophages/*immunology
Neutrophils/*immunology
Peritoneal Cavity/*pathology
Spleen/*immunology
Animals ; Cell Movement ; Cell Separation ; Flow Cytometry ; Inflammation/chemically induced ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Lymphotoxin-alpha/genetics ; Lymphotoxin-alpha/metabolism ; Mice ; Mice, Knockout ; Terpenes ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Metformin reduces morphine tolerance by inhibiting microglial-mediated neuroinflammation.
Autorzy:
Pan Y; Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Sun X; Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Jiang L; Department of Pharmacology, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Hu L; Department of Pharmacology, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Kong H; Department of Pharmacology, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Han Y; Jiangsu Province Key Laboratory of Anesthesiology, School of Anesthesiology, Xuzhou Medical College, Xuzhou, Jiangsu, 221004, People's Republic of China.
Qian C; Department of Pharmacology, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Song C; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221000, People's Republic of China.
Qian Y; Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.
Liu W; Department of Pharmacology, Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2016 Nov 17; Vol. 13 (1), pp. 294. Date of Electronic Publication: 2016 Nov 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Tolerance*
Analgesics, Opioid/*pharmacology
Hypoglycemic Agents/*pharmacology
Inflammation/*drug therapy
Metformin/*pharmacology
Microglia/*drug effects
Morphine/*pharmacology
AMP-Activated Protein Kinases/metabolism ; Animals ; Calcium-Binding Proteins/metabolism ; Cell Line, Transformed ; Cytokines/metabolism ; Dose-Response Relationship, Drug ; Inflammation/pathology ; Macrophage Activation/drug effects ; Mice ; Microfilament Proteins/metabolism ; Phosphorylation/drug effects ; Protein Kinase C/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Signal Transduction/drug effects ; Spinal Cord/cytology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation.
Autorzy:
Zhang Q; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Deng Y; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Lai W; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Guan X; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Sun X; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Han Q; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Wang F; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Pan X; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Ji Y; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Luo H; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Huang P; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Tang Y; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Gu L; The Center for Disease Control and Prevention of Chengdu Military Command, Chengdu 610021, China.
Dan G; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Yu J; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio 43210, USA.
Namaka M; Colleges of Pharmacy and Medicine, University of Manitoba, Apotex Center 750, McDermot Avenue, Winnipeg, R3E 0T5, MB, Canada.; Joint Laboratory of Biological Psychiatry between Shantou University Medical College and the College of Medicine University of Manitoba, Shantou 515063, China.
Zhang J; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Deng Y; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Li X; Institute of Materia Medica, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.; Center of Translational Medicine, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
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Źródło:
Scientific reports [Sci Rep] 2016 Jul 22; Vol. 6, pp. 30146. Date of Electronic Publication: 2016 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heart/*physiopathology
Heart Diseases/*metabolism
Inflammation/*metabolism
Reactive Oxygen Species/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Antioxidants/metabolism ; Female ; Heart/drug effects ; Heart Diseases/chemically induced ; Imidazoles/pharmacology ; Inflammation/chemically induced ; Isoproterenol/pharmacology ; Male ; NADPH Oxidases/metabolism ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Pregnancy ; Pyridines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 342

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