Temat: "Suppressor of Cytokine Signaling 1 Protein" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Effects of extracellular vesicles from adipose-derived stem cells on human keloid fibroblasts via the SOCS1/JAK2/STAT3 pathway.
Autorzy:: Ruan H; Department of Burn and Plastic Surgery, Zhenjiang First People's Hospital, Zhenjiang City, Jiangsu, China.
Wang J; Department of Burn and Plastic Surgery, Zhenjiang First People's Hospital, Zhenjiang City, Jiangsu, China.
Shi H; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Institute of Stem Cell, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Luan W; Department of Burn and Plastic Surgery, Zhenjiang First People's Hospital, Zhenjiang City, Jiangsu, China.; Pokaż więcej
Źródło:: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Apr; Vol. 23 (4), pp. 1404-1416. Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:: Journal Article
MeSH Terms:: Keloid*
Extracellular Vesicles*/metabolism
Humans ; STAT3 Transcription Factor/metabolism ; Janus Kinase 2/metabolism ; Collagen/metabolism ; Fibroblasts/metabolism ; Stem Cells/metabolism ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Suppressor of Cytokine Signaling 1 Protein/metabolism

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Skocz do pozycji: 2.

Tytuł:: LncRNA MALAT1 Participates in Protection of High-Molecular-Weight Hyaluronan against Smoke-Induced Acute Lung Injury by Upregulation of SOCS-1.
Autorzy:: Li S; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Li B; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Lang K; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Gong Y; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Cheng X; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Deng S; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Shi Q; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.
Zhao H; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 27; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Lung Injury*/drug therapy
Acute Lung Injury*/etiology
Acute Lung Injury*/genetics
Acute Lung Injury*/metabolism
Hyaluronic Acid*/pharmacology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Suppressor of Cytokine Signaling 1 Protein*/genetics
Suppressor of Cytokine Signaling 1 Protein*/metabolism
Animals ; Lung/pathology ; Mice ; Smoke ; Up-Regulation

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Skocz do pozycji: 3.

Tytuł:: Altered Expression Levels of MicroRNA-155 and SOCS-1 in Peripheral Blood Mononuclear Cells of Newly Diagnosed Breast Cancer Patients.
Autorzy:: Iranparast S; Department of Immunology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AND Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. .
Tahmasebi-Birgani M; Department of Medical Genetics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AND Cellular and Molecular Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. maryam_.
Motamedfar A; Department of Interventional Radiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AND Department of Radiology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. .
Amari A; Department of Immunology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AND Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. af_.
Ghafourian M; Department of Immunology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AND Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. mehri_.; Pokaż więcej
Źródło:: Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2022 Feb 06; Vol. 21 (1), pp. 12-19. Date of Electronic Publication: 2022 Feb 06.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*/diagnosis
Breast Neoplasms*/genetics
MicroRNAs*/genetics
Suppressor of Cytokine Signaling 1 Protein*/genetics
Female ; Humans ; Interleukin-6 ; Leukocytes, Mononuclear/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 4.

Tytuł:: SOCS1 Mediates Berberine-Induced Amelioration of Microglial Activated States in N9 Microglia Exposed to β Amyloid.
Autorzy:: Guo Q; Department of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.
Wang C; Department of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.
Xue X; Department of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.
Hu B; Department of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.
Bao H; Department of Pharmacy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Nov 05; Vol. 2021, pp. 9311855. Date of Electronic Publication: 2021 Nov 05 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Amyloid beta-Peptides/*metabolism
Microglia/*metabolism
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Alzheimer Disease/metabolism ; Arginase/metabolism ; Berberine/pharmacology ; Cell Line ; China ; Cytokines/metabolism ; Humans ; Inflammation/pathology ; Macrophages/metabolism ; Microglia/physiology ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Suppressor of Cytokine Signaling 1 Protein/physiology ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 5.

Tytuł:: Expression and significance of miR-30d-5p and SOCS1 in patients with recurrent implantation failure during implantation window.
Autorzy:: Zhao Y; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
He D; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Zeng H; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Luo J; Department of Obstetrics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Yang S; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen J; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Abdullah RK; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Liu N; Reproductive Medical Center, Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. .; Pokaż więcej
Źródło:: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2021 Sep 08; Vol. 19 (1), pp. 138. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
Embryo Implantation/*genetics
Embryo Transfer/*methods
Infertility, Female/*genetics
Suppressor of Cytokine Signaling 1 Protein/*genetics
Adult ; Endometrium/metabolism ; Endometrium/ultrastructure ; Female ; Humans ; Infertility, Female/therapy ; Leukemia Inhibitory Factor/genetics ; Leukemia Inhibitory Factor/metabolism ; MicroRNAs/genetics ; Microscopy, Electron, Scanning ; Pregnancy ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Suppressor of Cytokine Signaling 1 Protein/metabolism

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Skocz do pozycji: 6.

Tytuł:: SOCS1 methylation level is associated with prognosis in patients with acute-on-chronic hepatitis B liver failure.
Autorzy:: Li F; Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan, 250012, Shandong, China.
Zhang Y; Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan, 250012, Shandong, China.
Wang ZH; Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan, 250012, Shandong, China.
Gao S; Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan, 250012, Shandong, China.; Hepatology Institute of Shandong University, Jinan, 250012, China.
Fan YC; Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan, 250012, Shandong, China.; Hepatology Institute of Shandong University, Jinan, 250012, China.
Wang K; Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan, 250012, Shandong, China. .; Hepatology Institute of Shandong University, Jinan, 250012, China. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2023 May 06; Vol. 15 (1), pp. 79. Date of Electronic Publication: 2023 May 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hepatitis B, Chronic*/drug therapy
Hepatitis B, Chronic*/genetics
Acute-On-Chronic Liver Failure*/genetics
Acute-On-Chronic Liver Failure*/complications
Humans ; Glucocorticoids/therapeutic use ; DNA Methylation ; Prognosis ; Suppressor of Cytokine Signaling 1 Protein/genetics

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Skocz do pozycji: 7.

Tytuł:: A new reliable and highly specific monoclonal antibody to detect the C-terminal region of silencer of cytokine signaling 1.
Autorzy:: Weissinger SE; Institute of Pathology, University Hospital Ulm, Ulm, Germany.
Zahn M; Institute of Pathology, University Hospital Ulm, Ulm, Germany.
Marienfeld R; Institute of Pathology, University Hospital Ulm, Ulm, Germany.
Tessmer C; Antibody Unit, Genomics and Proteomics Core Facilities, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Moldenhauer G; Antibody Unit, Genomics and Proteomics Core Facilities, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Möller P; Institute of Pathology, University Hospital Ulm, Ulm, Germany.; Pokaż więcej
Źródło:: European journal of haematology [Eur J Haematol] 2021 Jul; Vol. 107 (1), pp. 74-80. Date of Electronic Publication: 2021 May 06.
Typ publikacji:: Journal Article
MeSH Terms:: Suppressor of Cytokine Signaling 1 Protein/*chemistry
Animals ; Antibodies, Monoclonal/chemistry ; Binding Sites ; Epitope Mapping ; Epitopes/chemistry ; HEK293 Cells ; Humans ; Hybridomas/metabolism ; Lymphoid Tissue/metabolism ; Lymphoma/metabolism ; Lymphoma, B-Cell/genetics ; Mice ; Mice, Inbred BALB C ; Mutation ; Palatine Tonsil/metabolism ; Protein Domains ; Signal Transduction ; Suppressor of Cytokine Signaling 1 Protein/metabolism ; Transfection

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Skocz do pozycji: 8.

Tytuł:: Downregulation of microRNA‑221 facilitates H1N1 influenza A virus replication through suppression of type‑IFN response by targeting the SOCS1/NF‑κB pathway.
Autorzy:: Zhang N; Department of Respiratory Medicine and Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.
Ma Y; Department of Respiratory Medicine and Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.
Tian Y; Department of Respiratory Medicine and Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.
Zhou Y; Department of Respiratory Medicine and Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.
Tang Y; Department of Respiratory Medicine and Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.
Hu S; Department of Respiratory Medicine and Intensive Care Unit, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471009, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Jul; Vol. 24 (1). Date of Electronic Publication: 2021 May 06.
Typ publikacji:: Journal Article
MeSH Terms:: Influenza A Virus, H1N1 Subtype/*immunology
Interferon Type I/*antagonists & inhibitors
MicroRNAs/*genetics
MicroRNAs/*immunology
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Virus Replication/*genetics
A549 Cells ; Down-Regulation ; Gene Knockdown Techniques ; Humans ; Immunity, Innate ; Influenza, Human/virology ; Interferon Type I/metabolism ; MicroRNAs/metabolism ; NF-kappa B/metabolism ; Signal Transduction ; Suppressor of Cytokine Signaling 1 Protein/genetics

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Skocz do pozycji: 9.

Tytuł:: Deregulation of PRDM5 promotes cell proliferation by regulating JAK/STAT signaling pathway through SOCS1 in human lung adenocarcinoma.
Autorzy:: Ren Y; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Wang Y; Sinovac Biotech Co. Ltd, Beijing, China.
Fang L; Qilu Medical University, Shandong, China.
Ma M; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Ge L; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Su C; University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Xin L; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
He J; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yang J; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Liu X; Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2023 Feb; Vol. 12 (4), pp. 4568-4578. Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/metabolism
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Humans ; Suppressor of Cytokine Signaling Proteins/genetics ; Cell Proliferation/genetics ; Signal Transduction ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Cell Line, Tumor ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Suppressor of Cytokine Signaling 1 Protein/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism

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Skocz do pozycji: 10.

Tytuł:: Suppressor of cytokine signaling-1 mimetic peptides attenuate lymphocyte activation in the MRL/lpr mouse autoimmune model.
Autorzy:: Sharma J; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Collins TD; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Roach T; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, 32610, USA.
Mishra S; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Lam BK; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Mohamed ZS; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Veal AE; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Polk TB; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Jones A; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Cornaby C; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, 32610, USA.
Haider MI; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Zeumer-Spataro L; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, 32610, USA.
Johnson HM; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA.
Morel LM; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, 32610, USA.
Larkin J 3rd; Department of Microbiology & Cell Science, University of Florida, Museum Road Building 981, PO Box 110700, Gainesville, FL, 32611, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Mar 18; Vol. 11 (1), pp. 6354. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autoimmune Diseases/*drug therapy
Forkhead Transcription Factors/*genetics
Lupus Erythematosus, Systemic/*drug therapy
Peptides/*pharmacology
Suppressor of Cytokine Signaling 1 Protein/*genetics
Animals ; Autoimmune Diseases/genetics ; Autoimmune Diseases/immunology ; Autoimmune Diseases/pathology ; B-Lymphocytes/drug effects ; Biomimetics ; CD4-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/drug effects ; Cytokines/genetics ; Interferon-gamma/genetics ; Janus Kinases/genetics ; Lupus Erythematosus, Systemic/genetics ; Lupus Erythematosus, Systemic/immunology ; Lymph Nodes/drug effects ; Lymph Nodes/immunology ; Lymphocytes/drug effects ; Lymphocytes/immunology ; Mice, Inbred MRL lpr ; Peptides/chemical synthesis ; STAT Transcription Factors/genetics ; Spleen/drug effects ; Spleen/immunology ; Suppressor of Cytokine Signaling 1 Protein/pharmacology ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; fas Receptor/genetics ; Mice

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Skocz do pozycji: 11.

Tytuł:: SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense.
Autorzy:: Klopfenstein N; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, United States of America.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Brandt SL; Vanderbilt Institute of Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Castellanos S; Vanderbilt Institute of Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Gunzer M; Institute for Experimental Immunology and Imaging, University Hospital, University Duisburg-Essen, Hufelandstrasse Essen, Germany.; Leibniz-Institut für Analytische Wissenschaften-ISAS -e.V, Dortmund, Germany.
Blackman A; Vanderbilt Institute of Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Serezani CH; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, United States of America.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Vanderbilt Institute of Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 Mar 10; Vol. 17 (3), pp. e1009387. Date of Electronic Publication: 2021 Mar 10 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Interferon Type I/*immunology
Methicillin-Resistant Staphylococcus aureus/*immunology
Staphylococcal Skin Infections/*immunology
Suppressor of Cytokine Signaling 1 Protein/*immunology
Animals ; Interferon Type I/metabolism ; Mice ; Mice, Inbred C57BL ; Skin/immunology ; Skin/microbiology ; Staphylococcal Skin Infections/microbiology ; Suppressor of Cytokine Signaling 1 Protein/metabolism

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Skocz do pozycji: 12.

Tytuł:: Global and promoter specific hypermethylation of tumor suppressor genes P16, SOCS1, and SHP1 in oral squamous cell carcinoma and oral submucous fibrosis.
Autorzy:: Ukey S; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Jain A; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Dwivedi S; All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.
Vishnoi JR; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Chugh A; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Purohit P; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Pareek P; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Elhence P; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Misra S; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Sharma P; All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.; Pokaż więcej
Źródło:: Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Jan 01; Vol. 19 (Suppl 2), pp. S551-S559. Date of Electronic Publication: 2023 Apr 29.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Squamous Cell*/pathology
Head and Neck Neoplasms*/genetics
Mouth Neoplasms*/pathology
Oral Submucous Fibrosis*/genetics
Oral Submucous Fibrosis*/pathology
Humans ; DNA Methylation ; Genes, Tumor Suppressor ; Squamous Cell Carcinoma of Head and Neck/genetics ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Suppressor of Cytokine Signaling 1 Protein/metabolism ; Protein Tyrosine Phosphatase, Non-Receptor Type 6/metabolism

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Skocz do pozycji: 13.

Tytuł:: LINC00669 insulates the JAK/STAT suppressor SOCS1 to promote nasopharyngeal cancer cell proliferation and invasion.
Autorzy:: Qing X; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Tan GL; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Liu HW; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Li W; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Ai JG; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Xiong SS; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Yang MQ; Department of Postgraduate Office, Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Wang TS; Department of Otolaryngology Head and Neck Surgery, The Third Xiangya Hospital, Central South University, Changsha, 410013, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2020 Aug 24; Vol. 39 (1), pp. 166. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Janus Kinase 1/*metabolism
Nasopharyngeal Neoplasms/*pathology
RNA, Long Noncoding/*genetics
STAT1 Transcription Factor/*metabolism
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Movement ; Cell Proliferation ; Humans ; Janus Kinase 1/genetics ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Nasopharyngeal Neoplasms/genetics ; Nasopharyngeal Neoplasms/metabolism ; Neoplasm Invasiveness ; Prognosis ; STAT1 Transcription Factor/genetics ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Survival Rate ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 14.

Tytuł:: Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma.
Autorzy:: Khan MGM; Immunology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.
Ghosh A; Cell biology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.
Variya B; Cell biology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.
Santharam MA; Cell biology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.
Ihsan AU; Cell biology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.
Ramanathan S; Immunology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.; Cell biology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada.; CRCHUS, Sherbrooke, Québec, J1H 5N4, Canada.
Ilangumaran S; Immunology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada. .; Cell biology graduate program, Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 North 12th avenue, Sherbrooke, QC, J1H 5N4, Canada. .; CRCHUS, Sherbrooke, Québec, J1H 5N4, Canada. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2020 Aug 17; Vol. 20 (1), pp. 774. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Biomarkers, Tumor/*genetics
Carcinoma, Hepatocellular/*genetics
Liver Neoplasms/*genetics
Suppressor of Cytokine Signaling 1 Protein/*genetics
Suppressor of Cytokine Signaling 3 Protein/*genetics
Animals ; Biomarkers, Tumor/metabolism ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Datasets as Topic ; Diethylnitrosamine/toxicity ; Gene Expression Regulation, Neoplastic ; Hepatocytes ; Humans ; Kaplan-Meier Estimate ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Liver Neoplasms, Experimental/genetics ; Liver Neoplasms, Experimental/pathology ; Male ; Mice, Knockout ; Predictive Value of Tests ; Prognosis ; RNA-Seq ; Signal Transduction/genetics ; Suppressor of Cytokine Signaling 1 Protein/metabolism ; Suppressor of Cytokine Signaling 3 Protein/metabolism

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Tytuł:: Yellow Fever Virus Down-Regulates mRNA Expression of SOCS1 in the Initial Phase of Infection in Human Cell Lines.
Autorzy:: Yakass MB; West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Legon-Accra 00233, Ghana.; Department of Biochemistry, Cell & Molecular Biology, University of Ghana, Legon-Accra 00233, Ghana.
Franco D; GSK Vaccines, 1330 Rixensart, Belgium.
Quaye O; West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Legon-Accra 00233, Ghana.; Department of Biochemistry, Cell & Molecular Biology, University of Ghana, Legon-Accra 00233, Ghana.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Jul 25; Vol. 12 (8). Date of Electronic Publication: 2020 Jul 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Down-Regulation*
Suppressor of Cytokine Signaling 1 Protein/*genetics
Virus Replication/*immunology
Yellow fever virus/*immunology
HEK293 Cells ; HeLa Cells ; Humans ; Protein Inhibitors of Activated STAT/genetics ; Protein Inhibitors of Activated STAT/immunology ; Suppressor of Cytokine Signaling 1 Protein/immunology

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Tytuł:: Suppressors of Cytokine Signaling (SOCS)1 and SOCS3 Proteins Are Mediators of Interleukin-10 Modulation of Inflammatory Responses Induced by Chlamydia muridarum and Its Major Outer Membrane Protein (MOMP) in Mouse J774 Macrophages.
Autorzy:: Duncan SA; Center for NanoBiotechnology Research (CNBR), Department of Biological Sciences, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA.
Sahu R; Center for NanoBiotechnology Research (CNBR), Department of Biological Sciences, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA.
Dixit S; Center for NanoBiotechnology Research (CNBR), Department of Biological Sciences, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA.
Singh SR; Center for NanoBiotechnology Research (CNBR), Department of Biological Sciences, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA.
Dennis VA; Center for NanoBiotechnology Research (CNBR), Department of Biological Sciences, Alabama State University, 1627 Harris Way, Montgomery, AL 36104, USA.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2020 Jun 24; Vol. 2020, pp. 7461742. Date of Electronic Publication: 2020 Jun 24 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Bacterial Outer Membrane Proteins/*toxicity
Chlamydia muridarum/*pathogenicity
Inflammation/*metabolism
Interleukin-10/*metabolism
Macrophages/*drug effects
Macrophages/*metabolism
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Suppressor of Cytokine Signaling 3 Protein/*metabolism
Animals ; Cell Line ; Flow Cytometry ; Mice ; Microscopy, Fluorescence ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Suppressor of Cytokine Signaling 3 Protein/genetics

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Tytuł:: Human microRNA-30 inhibits influenza virus infection by suppressing the expression of SOCS1, SOCS3, and NEDD4.
Autorzy:: Lin X; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.; Department of Preventive Veterinary Medicine, College of Animal Medicine, Huazhong Agricultural University, Wuhan, China.; Department of Biotechnology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China.
Yu S; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.; Department of Preventive Veterinary Medicine, College of Animal Medicine, Huazhong Agricultural University, Wuhan, China.
Ren P; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.; Department of Preventive Veterinary Medicine, College of Animal Medicine, Huazhong Agricultural University, Wuhan, China.
Sun X; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.; Department of Preventive Veterinary Medicine, College of Animal Medicine, Huazhong Agricultural University, Wuhan, China.
Jin M; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.; Department of Preventive Veterinary Medicine, College of Animal Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.; Pokaż więcej
Źródło:: Cellular microbiology [Cell Microbiol] 2020 May; Vol. 22 (5), pp. e13150. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Influenza A virus/*drug effects
Influenza, Human/*drug therapy
MicroRNAs/*pharmacology
Nuclear Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Suppressor of Cytokine Signaling 3 Protein/*metabolism
A549 Cells ; Down-Regulation ; HeLa Cells ; Host-Pathogen Interactions/immunology ; Humans ; Influenza A virus/genetics ; MicroRNAs/genetics ; Nuclear Proteins/genetics ; RNA-Binding Proteins/genetics ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Suppressor of Cytokine Signaling 3 Protein/genetics

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Skocz do pozycji: 18.

Tytuł:: Ulinastatin affects focal cerebral ischemia-reperfusion injury via SOCS1-mediated JAK2/STAT3 signalling pathway.
Autorzy:: Chen X; Department of Anesthesiology, Hengyang City Central Hospital, Hengyang, China.
Li P; Department of Anesthesiology, Hengyang City Central Hospital, Hengyang, China.
Huang R; Department of Anesthesiology, Hengyang City Central Hospital, Hengyang, China.
Zhang J; Department of Anesthesiology, Hengyang City Central Hospital, Hengyang, China.
Ouyang X; Department of Anesthesiology, Hengyang City Central Hospital, Hengyang, China.
Tan D; Department of Anesthesiology, Hengyang City Central Hospital, Hengyang, China.; Pokaż więcej
Źródło:: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2023 Jan; Vol. 50 (1), pp. 107-116. Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Brain Ischemia*/drug therapy
Reperfusion Injury*/drug therapy
Animals ; Rats ; Inflammation ; Neurons ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Janus Kinase 2

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Skocz do pozycji: 19.

Tytuł:: Small-molecule inhibitors of ubiquitin-specific protease 7 enhance type-I interferon antiviral efficacy by destabilizing SOCS1.
Autorzy:: Yuan Y; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Miao Y; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Zeng C; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Liu J; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.; The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China.
Chen X; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Qian L; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Wang X; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Qian F; The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China.
Yu Z; Department of Oncology, the First Affiliated Hospital of Soochow University, Suzhou, China.
Wang J; Department of Intensive Care Medicine, the First Affiliated Hospital of Soochow University, Suzhou, China.
Qian G; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
Fu Q; Soochow University Library, Suzhou, China.
Lv H; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
Zheng H; Institutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.; Pokaż więcej
Źródło:: Immunology [Immunology] 2020 Mar; Vol. 159 (3), pp. 309-321. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiviral Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Influenza A Virus, H1N1 Subtype/*drug effects
Interferon-alpha/*pharmacology
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Thiophenes/*pharmacology
Ubiquitin-Specific Peptidase 7/*antagonists & inhibitors
Vesiculovirus/*drug effects
A549 Cells ; HEK293 Cells ; HeLa Cells ; Host-Pathogen Interactions ; Humans ; Influenza A Virus, H1N1 Subtype/immunology ; Influenza A Virus, H1N1 Subtype/pathogenicity ; Janus Kinases/metabolism ; Protein Binding ; Protein Stability ; Proteolysis ; Signal Transduction ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Time Factors ; Ubiquitin-Specific Peptidase 7/metabolism ; Ubiquitination ; Vesiculovirus/immunology ; Vesiculovirus/pathogenicity

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Skocz do pozycji: 20.

Tytuł:: IL-21 regulates SOCS1 expression in autoreactive CD8 T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice.
Autorzy:: Sutherland APR; St Vincent's Institute of Medical Research, Melbourne, Australia. .; The University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia. .
Graham KL; St Vincent's Institute of Medical Research, Melbourne, Australia.; The University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
Papadimitriou M; St Vincent's Institute of Medical Research, Melbourne, Australia.
Jhala G; St Vincent's Institute of Medical Research, Melbourne, Australia.; The University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
Trivedi P; St Vincent's Institute of Medical Research, Melbourne, Australia.; The University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
Catterall T; St Vincent's Institute of Medical Research, Melbourne, Australia.
Fynch S; St Vincent's Institute of Medical Research, Melbourne, Australia.
Kay TWH; St Vincent's Institute of Medical Research, Melbourne, Australia.; The University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
Thomas HE; St Vincent's Institute of Medical Research, Melbourne, Australia. .; The University of Melbourne, Department of Medicine, St. Vincent's Hospital, Fitzroy, Victoria, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Oct 25; Vol. 9 (1), pp. 15302. Date of Electronic Publication: 2019 Oct 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*metabolism
Interleukins/*pharmacology
Islets of Langerhans/*drug effects
Suppressor of Cytokine Signaling 1 Protein/*metabolism
T-Lymphocytes, Cytotoxic/*metabolism
Animals ; CD8-Positive T-Lymphocytes/immunology ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Diabetes Mellitus, Type 1/genetics ; Diabetes Mellitus, Type 1/metabolism ; Humans ; Islets of Langerhans/metabolism ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, Transgenic ; Suppressor of Cytokine Signaling 1 Protein/genetics ; T-Lymphocytes, Cytotoxic/immunology

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