HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension.
Autorzy:
Almodovar S; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA. .; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. . Wade BE; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA. Porter KM; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA. Smith JM; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Lopez-Astacio RA; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Biology, University of Puerto Rico in Ponce, Ponce, PR, USA. Bijli K; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA. Kang BY; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA. Cribbs SK; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA. Guidot DM; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA. Molehin D; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA. McNair BK; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Pumarejo-Gomez L; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Perez Hernandez J; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Salazar EA; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA. Martinez EG; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA. Huang L; Department of Medicine, University of California San Francisco, San Francisco, CA, USA. Kessing CF; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA. Suarez-Martinez EB; Department of Biology, University of Puerto Rico in Ponce, Ponce, PR, USA. Pruitt K; Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA. Hsue PY; Department of Medicine, University of California San Francisco, San Francisco, CA, USA. Tyor WR; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA. Flores SC; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. SutliffRL; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University School of Medicine, Atlanta, GA, USA.; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA.
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 16; Vol. 10 (1), pp. 11696. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Lovastatin attenuates hypertension induced by renal tubule-specific knockout of ATP-binding cassette transporter A1, by inhibiting epithelial sodium channels.
Autorzy:
Wu MM; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China.; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Liang C; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Yu XD; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Song BL; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China.; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Yue Q; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Zhai YJ; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Linck V; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Cai YX; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Niu N; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Yang X; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Zhang BL; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Wang QS; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Zou L; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Zhang S; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Thai TL; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia. Ma J; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Atlanta Veterans Affairs Medical Center, Decatur, Georgia. SutliffRL; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Atlanta Veterans Affairs Medical Center, Decatur, Georgia. Zhang ZR; Departments of Cardiology and Clinic Pharmacy, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin Medical University Cancer Hospital, Harbin, China. Ma HP; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 Sep; Vol. 176 (18), pp. 3695-3711. Date of Electronic Publication: 2019 Jul 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Low-dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice.
Autorzy:
Chandler JD; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia. Wongtrakool C; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia Atlanta VA Medical Center, Decatur, Georgia. Banton SA; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia. Li S; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia. Orr ML; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia. Barr DB; Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia. Neujahr DC; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia. SutliffRL; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia Atlanta VA Medical Center, Decatur, Georgia. Go YM; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia. Jones DP; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia .
Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function.
Autorzy:
Kleinhenz JM; Atlanta VA Medical Center, Decatur, GA, United States of America; Emory University, Atlanta, GA, United States of America. Murphy TC; Atlanta VA Medical Center, Decatur, GA, United States of America; Emory University, Atlanta, GA, United States of America. Pokutta-Paskaleva AP; Georgia Institute of Technology, Atlanta, GA, United States of America. Gleason RL; Georgia Institute of Technology, Atlanta, GA, United States of America. Lyle AN; Emory University, Atlanta, GA, United States of America. Taylor WR; Atlanta VA Medical Center, Decatur, GA, United States of America; Emory University, Atlanta, GA, United States of America; Georgia Institute of Technology, Atlanta, GA, United States of America. Blount MA; Emory University, Atlanta, GA, United States of America. Cheng J; Emory University, Atlanta, GA, United States of America. Yang Q; University of Alabama at Birmingham, Birmingham, AL, United States of America. SutliffRL; Atlanta VA Medical Center, Decatur, GA, United States of America; Emory University, Atlanta, GA, United States of America. Hart CM; Atlanta VA Medical Center, Decatur, GA, United States of America; Emory University, Atlanta, GA, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Oct 09; Vol. 10 (10), pp. e0139756. Date of Electronic Publication: 2015 Oct 09 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Contractile force is enhanced in Aortas from pendrin null mice due to stimulation of angiotensin II-dependent signaling.
Autorzy:
SutliffRL; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Walp ER; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Kim YH; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Walker LA; Departments of Medicine and Cardiology, University of Colorado Health Sciences Center, Aurora, Colorado, United States of America. El-Ali AM; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Ma J; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Bonsall R; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia, United States of America. Ramosevac S; Department of Physiology, Emory University, Atlanta, Georgia, United States of America. Eaton DC; Department of Physiology, Emory University, Atlanta, Georgia, United States of America. Verlander JW; Department of Medicine, University of Florida, Gainesville, Florida, United States of America. Hansen L; School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America. Gleason RL Jr; School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America. Pham TD; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Hong S; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Pech V; Department of Medicine, Emory University, Atlanta, Georgia, United States of America. Wall SM; Department of Medicine, Emory University, Atlanta, Georgia, United States of America; Department of Physiology, Emory University, Atlanta, Georgia, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Aug 22; Vol. 9 (8), pp. e105101. Date of Electronic Publication: 2014 Aug 22 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Porter KM; Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Department of Pulmonary, Allergy and Critical Care Medicine, Atlanta, Georgia, United States of America. Kang BY; Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Department of Pulmonary, Allergy and Critical Care Medicine, Atlanta, Georgia, United States of America. Adesina SE; Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Department of Pulmonary, Allergy and Critical Care Medicine, Atlanta, Georgia, United States of America. Murphy TC; Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Department of Pulmonary, Allergy and Critical Care Medicine, Atlanta, Georgia, United States of America. Hart CM; Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Department of Pulmonary, Allergy and Critical Care Medicine, Atlanta, Georgia, United States of America. SutliffRL; Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Department of Pulmonary, Allergy and Critical Care Medicine, Atlanta, Georgia, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Jun 06; Vol. 9 (6), pp. e98532. Date of Electronic Publication: 2014 Jun 06 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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