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Tytuł:
Amphetamine alters an EEG marker of reward processing in humans and mice.
Autorzy:
Cavanagh JF; Psychology Department, University of New Mexico, Logan Hall, MSC03 2220, Albuquerque, NM, 87131, USA. .
Olguin SL; Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA.
Talledo JA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Kotz JE; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Roberts BZ; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Nungaray JA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Sprock J; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.; Desert Pacific Mental Illness Research, Education, and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, 92161, USA.
Gregg D; Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA.
Bhakta SG; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Light GA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.; Desert Pacific Mental Illness Research, Education, and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, 92161, USA.
Swerdlow NR; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Young JW; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.; Desert Pacific Mental Illness Research, Education, and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, 92161, USA.
Brigman JL; Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Mar; Vol. 239 (3), pp. 923-933. Date of Electronic Publication: 2022 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Amphetamine*/pharmacology
Reinforcement, Psychology*
Animals ; Biomarkers ; Electroencephalography ; Humans ; Mice ; Reward
Czasopismo naukowe
Tytuł:
Amphetamine improves rat 5-choice continuous performance test (5C-CPT) irrespective of concurrent low-dose haloperidol treatment.
Autorzy:
Young JW; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA. .; Research Service, VA San Diego Healthcare System, San Diego, CA, USA. .
Roberts BZ; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Breier M; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Swerdlow NR; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2020 Jul; Vol. 237 (7), pp. 1959-1972. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji:
Journal Article
MeSH Terms:
Amphetamine/*pharmacology
Attention/*drug effects
Central Nervous System Stimulants/*pharmacology
Choice Behavior/*drug effects
Dopamine Antagonists/*administration & dosage
Haloperidol/*administration & dosage
Animals ; Attention/physiology ; Choice Behavior/physiology ; Dose-Response Relationship, Drug ; Male ; Rats ; Rats, Long-Evans ; Schizophrenia/drug therapy ; Schizophrenia/physiopathology
Czasopismo naukowe
Tytuł:
The effects of age and sex on cognitive impairment in schizophrenia: Findings from the Consortium on the Genetics of Schizophrenia (COGS) study.
Autorzy:
Lee J; Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.; VA Greater Los Angeles Healthcare System, Los Angeles, California, United States of America.
Green MF; Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.; VA Greater Los Angeles Healthcare System, Los Angeles, California, United States of America.
Nuechterlein KH; Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.
Swerdlow NR; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.
Greenwood TA; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.
Hellemann GS; Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.; VA Greater Los Angeles Healthcare System, Los Angeles, California, United States of America.
Lazzeroni LC; Department of Psychiatry and Behavioral Science, Stanford University, Stanford, California, United States of America.; Department of Veterans Affairs Health Care System, Palo Alto, California, United States of America.
Light GA; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.; VISN22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, California, United States of America.
Radant AD; Department of Psychiatry and Behavioral Science, University of Washington, Seattle, Washington, United States of America.; VA Puget Sound Healthcare System, Seattle, Washington, United States of America.
Seidman LJ; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America.; Massachusetts Mental Health Center Public Psychiatry Devision of the Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
Siever LJ; Department of Psychiatry, The Mount Sinai School of Medicine, New York, New York, United States of America.; James J. Peters VA Medical Center, New York, New York, United States of America.
Silverman JM; Department of Psychiatry, The Mount Sinai School of Medicine, New York, New York, United States of America.; James J. Peters VA Medical Center, New York, New York, United States of America.
Sprock J; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.; VISN22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, California, United States of America.
Stone WS; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America.; Massachusetts Mental Health Center Public Psychiatry Devision of the Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
Sugar CA; Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.; VA Greater Los Angeles Healthcare System, Los Angeles, California, United States of America.; Department of Biostatistics, University of California Los Angeles, Los Angeles, California, United States of America.
Tsuang DW; Department of Psychiatry and Behavioral Science, University of Washington, Seattle, Washington, United States of America.; VA Puget Sound Healthcare System, Seattle, Washington, United States of America.
Tsuang MT; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.; Institute for Genomic Medicine, University of California, San Diego, California, United States of America.; Harvard Institute of Psychiatry Epidemiology and Genetics, Boston, Massachusetts, United States of America.
Turetsky BI; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Gur RC; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Gur RE; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Braff DL; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.; VISN22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, California, United States of America.
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Źródło:
PloS one [PLoS One] 2020 May 13; Vol. 15 (5), pp. e0232855. Date of Electronic Publication: 2020 May 13 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Schizophrenic Psychology*
Cognitive Dysfunction/*psychology
Adult ; Age Factors ; Aged ; Case-Control Studies ; Female ; Humans ; Linear Models ; Male ; Memory, Short-Term ; Middle Aged ; Neuropsychological Tests ; Sex Factors ; Young Adult
Czasopismo naukowe
Tytuł:
Premature responses in the five-choice serial reaction time task reflect rodents' temporal strategies: evidence from no-light and pharmacological challenges.
Autorzy:
Cope ZA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Halberstadt AL; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.
van Enkhuizen J; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.
Flynn AD; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Breier M; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Swerdlow NR; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.
Geyer MA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA.; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.
Young JW; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA, 92093-0804, USA. .; Research Service, VA San Diego Healthcare System, San Diego, CA, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2016 Oct; Vol. 233 (19-20), pp. 3513-25. Date of Electronic Publication: 2016 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Attention/*physiology
Behavior, Animal/*physiology
Choice Behavior/*physiology
Impulsive Behavior/*physiology
Reaction Time/*physiology
Animals ; Attention/drug effects ; Behavior, Animal/drug effects ; Cannabinoid Receptor Agonists/pharmacology ; Choice Behavior/drug effects ; Dronabinol/pharmacology ; Impulsive Behavior/drug effects ; Male ; Mice ; Rats ; Reaction Time/drug effects
Czasopismo naukowe
Tytuł:
Effects of acute memantine administration on MATRICS Consensus Cognitive Battery performance in psychosis: Testing an experimental medicine strategy.
Autorzy:
Bhakta SG; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Chou HH; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Rana B; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Talledo JA; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Balvaneda B; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Gaddis L; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Light GA; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA.
Swerdlow NR; Department of Psychiatry, UC San Diego School of Medicine, 9500 Gilman Dr., MC 0804, La Jolla, CA, 92093-0804, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2016 Jun; Vol. 233 (12), pp. 2399-410. Date of Electronic Publication: 2016 Apr 13.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:
Consensus*
Biomedical Research/*methods
Cognition/*drug effects
Excitatory Amino Acid Antagonists/*administration & dosage
Memantine/*administration & dosage
Psychotic Disorders/*drug therapy
Adult ; Cognition/physiology ; Cross-Over Studies ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Psychotic Disorders/diagnosis ; Psychotic Disorders/psychology
Czasopismo naukowe
Tytuł:
Future clinical uses of neurophysiological biomarkers to predict and monitor treatment response for schizophrenia.
Autorzy:
Light GA; VISN 22 Mental Illness, Research, Education, and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, California; Department of Psychiatry, University of California San Diego, La Jolla, California.
Swerdlow NR
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Źródło:
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2015 May; Vol. 1344, pp. 105-19. Date of Electronic Publication: 2015 Mar 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Brain*/metabolism
Brain*/physiopathology
Electroencephalography*
Schizophrenia*/metabolism
Schizophrenia*/physiopathology
Schizophrenia*/therapy
Biomarkers/*metabolism
Animals ; Humans ; Precision Medicine/methods ; Translational Research, Biomedical/methods
Czasopismo naukowe
Tytuł:
Amphetamine effects on MATRICS Consensus Cognitive Battery performance in healthy adults.
Autorzy:
Chou HH; Department of Psychiatry, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0804, USA.
Talledo JA
Lamb SN
Thompson WK
Swerdlow NR
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2013 May; Vol. 227 (1), pp. 165-76. Date of Electronic Publication: 2013 Jan 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuropsychological Tests*
Amphetamine/*pharmacology
Cognition/*drug effects
Psychomotor Performance/*drug effects
Adolescent ; Adult ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Cognition/physiology ; Cross-Over Studies ; Double-Blind Method ; Exploratory Behavior/drug effects ; Exploratory Behavior/physiology ; Female ; Heart Rate/drug effects ; Heart Rate/physiology ; Humans ; Inhibition, Psychological ; Male ; Psychomotor Performance/physiology ; Young Adult
Czasopismo naukowe
Tytuł:
Fronto-temporal-mesolimbic gene expression and heritable differences in amphetamine-disrupted sensorimotor gating in rats.
Autorzy:
Swerdlow NR; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093-0804, USA. />Shilling PD
Breier M
Trim RS
Light GA
Marie RS
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2012 Dec; Vol. 224 (3), pp. 349-62. Date of Electronic Publication: 2012 Jun 15.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Dextroamphetamine/*pharmacology
Dopamine Uptake Inhibitors/*pharmacology
Frontal Lobe/*drug effects
Gene Expression Regulation/*drug effects
Gene Expression Regulation/*genetics
Limbic System/*drug effects
Schizophrenia/*genetics
Sensory Gating/*drug effects
Temporal Lobe/*drug effects
Animals ; Behavior, Animal/drug effects ; Casein Kinase 1 epsilon/genetics ; Catechol O-Methyltransferase/genetics ; Dextroamphetamine/administration & dosage ; Dopamine/metabolism ; Dopamine Uptake Inhibitors/administration & dosage ; Female ; Frontal Lobe/metabolism ; Genotype ; Heredity ; Injections, Subcutaneous ; Limbic System/metabolism ; Male ; Neuregulin-1/genetics ; Phenotype ; RNA, Messenger/metabolism ; Rats ; Rats, Long-Evans ; Rats, Sprague-Dawley ; Receptors, Glutamate/genetics ; Reflex, Startle/drug effects ; Reflex, Startle/genetics ; Schizophrenia/physiopathology ; Sensory Gating/genetics ; Species Specificity ; Temporal Lobe/metabolism ; Time Factors
Czasopismo naukowe
Tytuł:
Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia.
Autorzy:
Light GA; VISN-22 Mental Illness, Research, Education, and Clinical Center (MIRECC), San Diego VA Health Care System, La Jolla, California, United States of America. />Swerdlow NR
Rissling AJ
Radant A
Sugar CA
Sprock J
Pela M
Geyer MA
Braff DL
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (7), pp. e39434. Date of Electronic Publication: 2012 Jul 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Biomarkers/*analysis
Endophenotypes/*analysis
Neuropsychological Tests/*standards
Schizophrenia/*diagnosis
Adult ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Schizophrenia/genetics ; Schizophrenia/physiopathology
Czasopismo naukowe
Tytuł:
Association analysis of 94 candidate genes and schizophrenia-related endophenotypes.
Autorzy:
Greenwood TA; Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America.
Light GA
Swerdlow NR
Radant AD
Braff DL
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (1), pp. e29630. Date of Electronic Publication: 2012 Jan 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Endophenotypes*
Genetic Association Studies*
Genetic Predisposition to Disease*
Schizophrenia/*genetics
Adolescent ; Adult ; Aged ; Black People/genetics ; Case-Control Studies ; Female ; Gene Regulatory Networks/genetics ; Humans ; Male ; Middle Aged ; Signal Transduction/genetics ; White People/genetics ; Young Adult
Czasopismo naukowe
Tytuł:
Probing the molecular basis for an inherited sensitivity to the startle-gating disruptive effects of apomorphine in rats.
Autorzy:
Swerdlow NR; Department of Psychiatry, School of Medicine, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804, USA. />Breier MR
Saint Marie RL
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2011 Aug; Vol. 216 (3), pp. 401-10. Date of Electronic Publication: 2011 Mar 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Inhibition, Psychological*
Quantitative Trait, Heritable*
Apomorphine/*pharmacology
Cyclic AMP Response Element-Binding Protein/*metabolism
Dopamine Agonists/*pharmacology
Sensory Gating/*drug effects
Animals ; Behavior, Animal/drug effects ; Immunohistochemistry ; Male ; Nucleus Accumbens/drug effects ; Nucleus Accumbens/metabolism ; Phosphorylation ; Rats ; Rats, Long-Evans ; Rats, Sprague-Dawley ; Sensory Gating/genetics ; Species Specificity
Czasopismo naukowe
Tytuł:
Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study.
Autorzy:
Radant AD; Department of Psychiatry and Behavioral Sciences, University of Washington and Department of Veteran Affairs, VISN-20, Mental Illness Research, Education, and Clinical Center, Seattle, Washington 98108, USA. />Dobie DJ
Calkins ME
Olincy A
Braff DL
Cadenhead KS
Freedman R
Green MF
Greenwood TA
Gur RE
Gur RC
Light GA
Meichle SP
Millard SP
Mintz J
Nuechterlein KH
Schork NJ
Seidman LJ
Siever LJ
Silverman JM
Stone WS
Swerdlow NR
Tsuang MT
Turetsky BI
Tsuang DW
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Źródło:
Psychophysiology [Psychophysiology] 2010 Sep; Vol. 47 (5), pp. 846-56. Date of Electronic Publication: 2010 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
Schizophrenic Psychology*
Saccades/*physiology
Schizophrenia/*genetics
Adult ; Artifacts ; Female ; Humans ; Linear Models ; Male ; Middle Aged ; Psychomotor Performance/physiology ; Sample Size
Czasopismo naukowe
Tytuł:
Neural basis for a heritable phenotype: differences in the effects of apomorphine on startle gating and ventral pallidal GABA efflux in male Sprague-Dawley and Long-Evans rats.
Autorzy:
Qu Y; Department of Psychiatry, UCSD School of Medicine, 9500 Gilman Dr., La Jolla, CA 92093-0804, USA.
Saint Marie RL
Breier MR
Ko D
Stouffer D
Parsons LH
Swerdlow NR
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2009 Dec; Vol. 207 (2), pp. 271-80. Date of Electronic Publication: 2009 Sep 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Apomorphine/*pharmacology
Dopamine Agonists/*pharmacology
Reflex, Startle/*drug effects
gamma-Aminobutyric Acid/*drug effects
Animals ; Electrophoresis, Capillary ; Fluorescence ; Globus Pallidus/drug effects ; Globus Pallidus/metabolism ; Glutamic Acid/metabolism ; Male ; Phenotype ; Rats ; Rats, Long-Evans ; Rats, Sprague-Dawley ; Sensory Gating/drug effects ; Species Specificity ; Time Factors ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł:
Pramipexole effects on startle gating in rats and normal men.
Autorzy:
Swerdlow NR; Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA. />Lelham SA
Sutherland Owens AN
Chang WL
Sassen SD
Talledo JA
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2009 Sep; Vol. 205 (4), pp. 689-98. Date of Electronic Publication: 2009 Jun 09.
Typ publikacji:
Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Benzothiazoles/*pharmacology
Dopamine Agonists/*pharmacology
Personality/*physiology
Receptors, Dopamine D3/*agonists
Sensory Gating/*drug effects
Adolescent ; Adult ; Animals ; Cross-Over Studies ; Humans ; Male ; Pramipexole ; Rats ; Rats, Sprague-Dawley ; Sensory Gating/physiology ; Sleep Stages/drug effects
Czasopismo naukowe
Tytuł:
Amphetamine effects on startle gating in normal women and female rats.
Autorzy:
Talledo JA; Department of Psychiatry, University of California, San Diego,La Jolla, CA 92093, USA.
Sutherland Owens AN
Schortinghuis T
Swerdlow NR
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2009 May; Vol. 204 (1), pp. 165-75. Date of Electronic Publication: 2009 Jan 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Amphetamine/*pharmacology
Central Nervous System Stimulants/*pharmacology
Dopamine Agonists/*pharmacology
Psychomotor Performance/*drug effects
Reflex, Startle/*drug effects
Adult ; Amphetamine/administration & dosage ; Animals ; Central Nervous System Stimulants/administration & dosage ; Cross-Over Studies ; Dopamine/physiology ; Dopamine Agonists/administration & dosage ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Humans ; Nucleus Accumbens/physiology ; Psychomotor Performance/physiology ; Rats ; Rats, Long-Evans ; Rats, Sprague-Dawley ; Reflex, Startle/physiology ; Species Specificity
Czasopismo naukowe
Tytuł:
Realistic expectations of prepulse inhibition in translational models for schizophrenia research.
Autorzy:
Swerdlow NR; Department of Psychiatry, UCSD School of Medicine, La Jolla, CA, 92093-0804, USA, .
Weber M
Qu Y
Light GA
Braff DL
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2008 Aug; Vol. 199 (3), pp. 331-88. Date of Electronic Publication: 2008 Jun 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Models, Psychological*
Schizophrenic Psychology*
Antipsychotic Agents/*therapeutic use
Reflex, Startle/*drug effects
Reflex, Startle/*physiology
Schizophrenia/*drug therapy
Animals ; Disease Models, Animal ; Humans ; Reflex, Startle/genetics ; Schizophrenia/genetics
Czasopismo naukowe
Tytuł:
Preattentive sensory processing as indexed by the MMN and P3a brain responses is associated with cognitive and psychosocial functioning in healthy adults.
Autorzy:
Light GA; Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093-0804, USA. />Swerdlow NR
Braff DL
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Źródło:
Journal of cognitive neuroscience [J Cogn Neurosci] 2007 Oct; Vol. 19 (10), pp. 1624-32.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Field Dependence-Independence*
Attention/*physiology
Discrimination, Psychological/*physiology
Evoked Potentials, Auditory/*physiology
Orientation/*physiology
Acoustic Stimulation ; Adult ; Female ; Humans ; Male ; Mental Recall/physiology ; Reference Values
Czasopismo naukowe
Tytuł:
Pharmacokinetic and behavioral characterization of a long-term antipsychotic delivery system in rodents and rabbits.
Autorzy:
Metzger KL; Stanley Center for Experimental Therapeutics in Psychiatry, Translational Research Laboratories, University of Pennsylvania, Philadelphia, PA 19104, USA.
Shoemaker JM
Kahn JB
Maxwell CR
Liang Y
Tokarczyk J
Kanes SJ
Hans M
Lowman AM
Dan N
Winey KI
Swerdlow NR
Siegel SJ
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2007 Feb; Vol. 190 (2), pp. 201-11. Date of Electronic Publication: 2006 Nov 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Inhibition, Psychological*
Antipsychotic Agents/*administration & dosage
Antipsychotic Agents/*pharmacokinetics
Arousal/*drug effects
Haloperidol/*administration & dosage
Haloperidol/*pharmacokinetics
Reflex, Startle/*drug effects
Acoustic Stimulation ; Amphetamine/antagonists & inhibitors ; Amphetamine/pharmacology ; Animals ; Apomorphine/antagonists & inhibitors ; Apomorphine/pharmacology ; Arousal/physiology ; Biocompatible Materials ; Drug Implants ; Lactic Acid ; Long-Term Care ; Male ; Mice ; Mice, Inbred C57BL ; Polyglycolic Acid ; Polylactic Acid-Polyglycolic Acid Copolymer ; Polymers ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Reflex, Startle/physiology
Czasopismo naukowe
Tytuł:
Separable noradrenergic and dopaminergic regulation of prepulse inhibition in rats: implications for predictive validity and Tourette Syndrome.
Autorzy:
Swerdlow NR; Department of Psychiatry, UCSD School of Medicine, La Jolla, CA 2093-0804, USA. />Bongiovanni MJ
Tochen L
Shoemaker JM
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2006 Jun; Vol. 186 (2), pp. 246-54. Date of Electronic Publication: 2006 Apr 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Tourette Syndrome*/drug therapy
Tourette Syndrome*/metabolism
Tourette Syndrome*/psychology
Adrenergic Agents/*pharmacology
Antipsychotic Agents/*pharmacology
Dopamine Agents/*pharmacology
Receptors, Adrenergic/*physiology
Receptors, Dopamine/*physiology
Reflex, Startle/*drug effects
Adrenergic Agents/therapeutic use ; Animals ; Antipsychotic Agents/therapeutic use ; Dopamine Agents/therapeutic use ; Male ; Predictive Value of Tests ; Rats ; Rats, Sprague-Dawley ; Receptors, Adrenergic/metabolism ; Receptors, Dopamine/metabolism ; Reflex, Startle/physiology
Czasopismo naukowe

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