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Tytuł :
Transcriptional Programs of Circuit Assembly in the Drosophila Visual System.
Autorzy :
Kurmangaliyev YZ; Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Yoo J; Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Neuroscience Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Valdes-Aleman J; Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Sanfilippo P; Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Zipursky SL; Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 23; Vol. 108 (6), pp. 1045-1057.e6. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drosophila/*physiology
Neurogenesis/*physiology
Neurons/*physiology
Visual Pathways/*physiology
Animals ; Axons/physiology ; Synapses/physiology ; Transcriptome
Czasopismo naukowe
Tytuł :
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices.
Autorzy :
Imig C; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany. Electronic address: .
López-Murcia FJ; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
Maus L; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany; Georg August University School of Science, Georg August University Göttingen, 37073 Göttingen, Germany.
García-Plaza IH; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany; Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences, 37077 Göttingen, Germany.
Mortensen LS; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
Schwark M; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
Schwarze V; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
Angibaud J; University of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, IINS, UMR 5297, F-33000 Bordeaux, France.
Nägerl UV; University of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, IINS, UMR 5297, F-33000 Bordeaux, France.
Taschenberger H; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.
Brose N; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' University of Göttingen, 37073 Göttingen, Germany. Electronic address: .
Cooper BH; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 843-860.e8. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Excitatory Postsynaptic Potentials/*physiology
Hippocampus/*physiology
Hippocampus/*ultrastructure
Synaptic Membranes/*physiology
Synaptic Membranes/*ultrastructure
Animals ; Gene Knock-In Techniques/methods ; Mice ; Mice, Transgenic ; Microscopy, Electron/methods ; Microtomy/methods ; Organ Culture Techniques ; Protein Transport/physiology
Czasopismo naukowe
Tytuł :
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.
Autorzy :
Henneberger C; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), 53175 Bonn, Germany. Electronic address: .
Bard L; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Panatier A; INSERM U1215, Neurocentre Magendie, 33000 Bordeaux, France; Université de Bordeaux, 33000 Bordeaux, France; Interdisciplinary Institute for Neuroscience, CNRS UMR 5297, 33000 Bordeaux, France.
Reynolds JP; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Kopach O; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Medvedev NI; Life Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Minge D; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Herde MK; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Anders S; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany.
Kraev I; Life Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Heller JP; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Rama S; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Zheng K; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Jensen TP; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Sanchez-Romero I; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
Jackson CJ; Research School of Chemistry, Australian National University, Acton, ACT 2601, Australia.
Janovjak H; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria; EMBL Australia, Australian Regenerative Medicine Institute, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, VIC 3800, Australia.
Ottersen OP; Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway; Karolinska Institutet, 171 77 Stockholm, Sweden.
Nagelhus EA; Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.
Oliet SHR; INSERM U1215, Neurocentre Magendie, 33000 Bordeaux, France; Université de Bordeaux, 33000 Bordeaux, France.
Stewart MG; Life Sciences, The Open University, Milton Keynes MK7 6AA, UK. Electronic address: .
Nägerl UV; Université de Bordeaux, 33000 Bordeaux, France; Interdisciplinary Institute for Neuroscience, CNRS UMR 5297, 33000 Bordeaux, France. Electronic address: .
Rusakov DA; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 919-936.e11. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Glutamic Acid/*metabolism
Long-Term Potentiation/*physiology
Synapses/*metabolism
Animals ; Astrocytes/ultrastructure ; Female ; Imaging, Three-Dimensional/methods ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Organ Culture Techniques ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Synapses/ultrastructure
Czasopismo naukowe
Tytuł :
Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents.
Autorzy :
Liu Z; Department of Neuroscience, Washington University in St. Louis, St. Louis, MO, USA.
Kimura Y; Department of Neurobiology, National Institute for Basic Biology, Okazaki, Japan.
Higashijima SI; Department of Neurobiology, National Institute for Basic Biology, Okazaki, Japan.
Hildebrand DGC; Laboratory of Neural Systems, The Rockefeller University, New York, NY, USA.
Morgan JL; Department of Ophthalmology, Washington University in St. Louis, St. Louis, MO, USA.
Bagnall MW; Department of Neuroscience, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Nov 25; Vol. 108 (4), pp. 748-762.e4. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons, Afferent/*physiology
Otolithic Membrane/*physiology
Vestibular Nuclei/*physiology
Animals ; Electric Stimulation ; Evoked Potentials, Somatosensory/physiology ; Gene Knock-In Techniques ; Microscopy, Electron ; Neurons/physiology ; Neurons/ultrastructure ; Neurons, Afferent/ultrastructure ; Vestibular Nuclei/ultrastructure ; Zebrafish
Czasopismo naukowe
Tytuł :
Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism.
Autorzy :
Cheadle L; Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA.
Rivera SA; Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA.
Phelps JS; Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA; Program in Neuroscience, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA.
Ennis KA; Research and Early Development, Biogen, 115 Broadway, Cambridge, MA 04142, USA.
Stevens B; Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Burkly LC; Research and Early Development, Biogen, 115 Broadway, Cambridge, MA 04142, USA.
Lee WA; Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Greenberg ME; Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Nov 11; Vol. 108 (3), pp. 451-468.e9. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Microglia/*physiology
Microglia/*ultrastructure
Neuronal Plasticity/*physiology
Synapses/*physiology
Synapses/*ultrastructure
Animals ; Cytokine TWEAK/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Electron, Transmission/methods ; Neurons/metabolism ; Neurons/ultrastructure ; Photic Stimulation ; TWEAK Receptor/metabolism ; Visual Pathways/physiology ; Visual Pathways/ultrastructure
Czasopismo naukowe
Tytuł :
Synapse and Active Zone Assembly in the Absence of Presynaptic Ca Entry.
Autorzy :
Held RG; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Liu C; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Ma K; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, and University of Chinese Academy of Sciences, Beijing 100101, China.
Ramsey AM; Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Tarr TB; Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
De Nola G; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Wang SSH; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Wang J; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
van den Maagdenberg AMJM; Departments of Human Genetics and Neurology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.
Schneider T; Institute for Neurophysiology, University of Cologne, Köln 50931, Germany.
Sun J; State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, and University of Chinese Academy of Sciences, Beijing 100101, China.
Blanpied TA; Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Kaeser PS; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Aug 19; Vol. 107 (4), pp. 667-683.e9. Date of Electronic Publication: 2020 Jun 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels/*metabolism
Presynaptic Terminals/*metabolism
Synapses/*metabolism
Synaptic Transmission/*physiology
Animals ; Calcium/metabolism ; Calcium Channels/genetics ; Exocytosis/physiology ; Mice, Knockout ; Neurons/metabolism ; Synaptic Vesicles/metabolism
Czasopismo naukowe
Tytuł :
SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Autorzy :
Sauerbeck AD; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Gangolli M; McKelvey School of Engineering, Washington University, St. Louis, MO 63130, USA; Currently, Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Reitz SJ; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Salyards MH; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Kim SH; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hemingway C; Institute of Clinical Neuroimmunology, Ludwig-Maximilians Universität München, Munich 82152, Germany.
Gratuze M; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Makkapati T; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Kerschensteiner M; Institute of Clinical Neuroimmunology, Ludwig-Maximilians Universität München, Munich 82152, Germany; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany.
Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Brody DL; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA; Currently, Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Kummer TT; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jul 22; Vol. 107 (2), pp. 257-273.e5. Date of Electronic Publication: 2020 May 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Injuries, Traumatic/*pathology
Central Nervous System/*diagnostic imaging
Nanostructures/*ultrastructure
Neural Pathways/*diagnostic imaging
Neural Pathways/*ultrastructure
Neuroimaging/*methods
Synapses/*ultrastructure
Animals ; Brain Mapping ; Central Nervous System/ultrastructure ; Cerebral Cortex/pathology ; Humans ; Mammals ; Mice
Czasopismo naukowe
Tytuł :
Fovea-like Photoreceptor Specializations Underlie Single UV Cone Driven Prey-Capture Behavior in Zebrafish.
Autorzy :
Yoshimatsu T; School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK. Electronic address: .
Schröder C; Institute of Ophthalmic Research, University of Tübingen, Tübingen 72076, Germany; Center for Integrative Neuroscience, University of Tübingen, Tübingen 72076, Germany.
Nevala NE; School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Berens P; Institute of Ophthalmic Research, University of Tübingen, Tübingen 72076, Germany; Center for Integrative Neuroscience, University of Tübingen, Tübingen 72076, Germany; Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen 72076, Germany.
Baden T; School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK; Institute of Ophthalmic Research, University of Tübingen, Tübingen 72076, Germany. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jul 22; Vol. 107 (2), pp. 320-337.e6. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Photoreceptor Cells, Vertebrate/*physiology
Predatory Behavior/*physiology
Retinal Cone Photoreceptor Cells/*physiology
Zebrafish/*physiology
Animals ; Calcium Signaling ; Computer Simulation ; Glutamic Acid/metabolism ; Larva ; Light ; Light Signal Transduction ; Retinal Horizontal Cells/physiology ; Synapses/physiology ; Transcriptome ; Ultraviolet Rays ; Visual Fields
Czasopismo naukowe
Tytuł :
SNAREopathies: Diversity in Mechanisms and Symptoms.
Autorzy :
Verhage M; Department of Functional Genomics, Vrije Universiteit (VU) Amsterdam, De Boelelaan 1085, Amsterdam 1081 HV, the Netherlands; Department of Clinical Genetics, UMC Amsterdam, De Boelelaan 1085, Amsterdam 1081 HV, the Netherlands. Electronic address: .
Sørensen JB; Department of Neuroscience, University of Copenhagen, 2200 Copenhagen N, Denmark. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jul 08; Vol. 107 (1), pp. 22-37. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neurodevelopmental Disorders/*genetics
Neurodevelopmental Disorders/*physiopathology
SNARE Proteins/*physiology
Humans ; Mutation
Czasopismo naukowe
Tytuł :
A Synaptic Circuit Required for Acquisition but Not Recall of Social Transmission of Food Preference.
Autorzy :
Wang CY; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: .
Liu Z; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Ng YH; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Südhof TC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Jul 08; Vol. 107 (1), pp. 144-157.e4. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Food Preferences/*physiology
Learning/*physiology
Olfactory Bulb/*physiology
Olfactory Pathways/*physiology
Synaptic Transmission/*physiology
Animals ; Cues ; Membrane Glycoproteins/metabolism ; Mental Recall/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neurons/physiology ; Receptors, Complement/metabolism
Czasopismo naukowe
Tytuł :
LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ.
Autorzy :
Roppongi RT; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Dhume SH; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Padmanabhan N; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Silwal P; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Zahra N; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Karimi B; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Bomkamp C; Djavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B, Canada.
Patil CS; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB R3E 0T6, Canada.
Champagne-Jorgensen K; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Twilley RE; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Zhang P; Djavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B, Canada.
Jackson MF; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB R3E 0T6, Canada.
Siddiqui TJ; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Apr 08; Vol. 106 (1), pp. 108-125.e12. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium-Binding Proteins/*genetics
Dentate Gyrus/*metabolism
Membrane Proteins/*genetics
Nerve Tissue Proteins/*genetics
Neural Cell Adhesion Molecules/*genetics
Neurons/*metabolism
Receptor-Like Protein Tyrosine Phosphatases, Class 2/*genetics
Synapses/*metabolism
Animals ; Calcium-Binding Proteins/metabolism ; Dentate Gyrus/pathology ; Heparitin Sulfate/metabolism ; Membrane Proteins/metabolism ; Mice ; Nerve Tissue Proteins/metabolism ; Neural Cell Adhesion Molecules/metabolism ; Receptor-Like Protein Tyrosine Phosphatases, Class 2/metabolism ; Synapses/pathology
Czasopismo naukowe
Tytuł :
LRRTM4: A Novel Regulator of Presynaptic Inhibition and Ribbon Synapse Arrangements of Retinal Bipolar Cells.
Autorzy :
Sinha R; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, USA; McPherson Eye Research Institute, University of Wisconsin, Madison, WI, USA; Department of Physiology and Biophysics, University of Washington, Seattle, WA, USA.
Siddiqui TJ; Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Center, Winnipeg, MB R3E 0Z3, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, MB, Canada.
Padmanabhan N; Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Center, Winnipeg, MB R3E 0Z3, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, MB, Canada.
Wallin J; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, USA.
Zhang C; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Karimi B; Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Center, Winnipeg, MB R3E 0Z3, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, MB, Canada.
Rieke F; Department of Physiology and Biophysics, University of Washington, Seattle, WA, USA.
Craig AM; Djavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Wong RO; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Hoon M; McPherson Eye Research Institute, University of Wisconsin, Madison, WI, USA; Department of Biological Structure, University of Washington, Seattle, WA, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Mar 18; Vol. 105 (6), pp. 1007-1017.e5. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Proteins/*physiology
Nerve Tissue Proteins/*physiology
Neural Inhibition/*physiology
Presynaptic Terminals/*physiology
Retinal Bipolar Cells/*physiology
Animals ; Female ; Male ; Membrane Proteins/biosynthesis ; Membrane Proteins/genetics ; Mice ; Mice, Knockout ; Mice, Transgenic ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Receptors, GABA/metabolism ; Receptors, GABA/physiology ; Retina/metabolism ; Vesicular Inhibitory Amino Acid Transport Proteins/genetics ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł :
Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration.
Autorzy :
Smith HL; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Freeman OJ; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Butcher AJ; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Holmqvist S; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge, UK.
Humoud I; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Schätzl T; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Hughes DT; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Verity NC; MRC Toxicology Unit, Hodgkin Building, Leicester, UK.
Swinden DP; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Hayes J; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
de Weerd L; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK.
Rowitch DH; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge, UK.
Franklin RJM; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge, UK.
Mallucci GR; Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Mar 04; Vol. 105 (5), pp. 855-866.e5. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Eukaryotic Initiation Factor-2B/*metabolism
Neurodegenerative Diseases/*metabolism
Prion Diseases/*metabolism
Synapses/*metabolism
Unfolded Protein Response/*physiology
eIF-2 Kinase/*metabolism
Animals ; Endoplasmic Reticulum Stress/drug effects ; Enzyme Inhibitors/pharmacology ; In Vitro Techniques ; Memory ; Mice ; Phosphorylation ; Protein Biosynthesis ; Protein Phosphatase 1/genetics ; Protein Phosphatase 1/metabolism ; Signal Transduction ; Thapsigargin/pharmacology ; Transcriptome ; Tunicamycin/pharmacology ; Unfolded Protein Response/drug effects
Czasopismo naukowe

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