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Tytuł :
Functional mosaic organization of neuroligins in neuronal circuits.
Autorzy :
Qin L; School of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.
Guo S; School of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.
Han Y; School of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.
Wang X; School of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.
Zhang B; School of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Aug; Vol. 77 (16), pp. 3117-3127. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain/*physiology
Nerve Net/*physiology
Neurons/*physiology
Animals ; Brain/metabolism ; Cell Adhesion Molecules, Neuronal/metabolism ; Humans ; Nerve Net/metabolism ; Neurons/metabolism ; Synapses/metabolism ; Synapses/physiology ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł :
LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ.
Autorzy :
Roppongi RT; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Dhume SH; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Padmanabhan N; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Silwal P; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Zahra N; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Karimi B; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Bomkamp C; Djavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B, Canada.
Patil CS; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB R3E 0T6, Canada.
Champagne-Jorgensen K; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Twilley RE; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Zhang P; Djavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B, Canada.
Jackson MF; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, MB R3E 0T6, Canada.
Siddiqui TJ; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB R3E 0Z3, Canada; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Apr 08; Vol. 106 (1), pp. 108-125.e12. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium-Binding Proteins/*genetics
Dentate Gyrus/*metabolism
Membrane Proteins/*genetics
Nerve Tissue Proteins/*genetics
Neural Cell Adhesion Molecules/*genetics
Neurons/*metabolism
Receptor-Like Protein Tyrosine Phosphatases, Class 2/*genetics
Synapses/*metabolism
Animals ; Calcium-Binding Proteins/metabolism ; Dentate Gyrus/pathology ; Heparitin Sulfate/metabolism ; Membrane Proteins/metabolism ; Mice ; Nerve Tissue Proteins/metabolism ; Neural Cell Adhesion Molecules/metabolism ; Receptor-Like Protein Tyrosine Phosphatases, Class 2/metabolism ; Synapses/pathology
Czasopismo naukowe
Tytuł :
Protecting Connections from Synapse Elimination.
Autorzy :
Sell GL; Center for Neuroscience, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.
McAllister AK; Center for Neuroscience, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: .
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Źródło :
Trends in neurosciences [Trends Neurosci] 2020 Nov; Vol. 43 (11), pp. 841-842. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Neurons*
Synapses*
Complement System Proteins ; Microglia
Czasopismo naukowe
Tytuł :
Presynaptically silent synapses are modulated by the density of surrounding astrocytes.
Autorzy :
Oyabu K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Takeda K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Kawano H; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Kubota K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Watanabe T; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Harata NC; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Katsurabayashi S; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan. Electronic address: .
Iwasaki K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Oct; Vol. 144 (2), pp. 76-82. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Synaptic Transmission*
Astrocytes/*physiology
Brain/*cytology
Neurons/*physiology
Synapses/*physiology
Animals ; Astrocytes/pathology ; Cells, Cultured ; Excitatory Postsynaptic Potentials ; Female ; Mice, Inbred ICR ; Neurons/pathology ; Phylogeny ; Pregnancy
Czasopismo naukowe
Tytuł :
Short Communication: An Updated Design to Implement Artificial Neuron Synaptic Behaviors in One Device with a Control Gate.
Autorzy :
Qi S; Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, People's Republic of China.
Hu Y; Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, People's Republic of China.
Dai C; Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, People's Republic of China.
Chen P; Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, People's Republic of China.
Wu Z; Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, People's Republic of China.
Webster TJ; Department of Chemical Engineering, Northeastern University, Boston, MA, USA.
Dai M; Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, People's Republic of China.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2020 Aug 20; Vol. 15, pp. 6239-6245. Date of Electronic Publication: 2020 Aug 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Electrophysiology/*instrumentation
Neurons/*physiology
Synapses/*physiology
Artificial Intelligence ; Electrodes ; Electrophysiology/methods ; Equipment Design ; Gold/chemistry ; Microscopy, Electron, Scanning/instrumentation ; Nickel/chemistry ; Semiconductors ; Synapses/chemistry ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
Kirrel3-Mediated Synapse Formation Is Attenuated by Disease-Associated Missense Variants.
Autorzy :
Taylor MR; Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84112.
Martin EA; Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84112.
Sinnen B; Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84112.
Trilokekar R; Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84112.
Ranza E; Service of Genetic Medicine, Geneva University Hospitals, 1211 Geneva 14, Switzerland.
Antonarakis SE; Service of Genetic Medicine, Geneva University Hospitals, 1211 Geneva 14, Switzerland.; Department of Genetic Medicine and Development, University of Geneva Medical Faculty, 1211 Geneva 4, Switzerland.
Williams ME; Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84112 .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jul 08; Vol. 40 (28), pp. 5376-5388. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation, Missense*
Hippocampus/*metabolism
Membrane Proteins/*genetics
Neurons/*metabolism
Synapses/*metabolism
Animals ; Autistic Disorder/genetics ; Autistic Disorder/metabolism ; Cell Adhesion/physiology ; Cells, Cultured ; Female ; Hippocampus/cytology ; Intellectual Disability/genetics ; Intellectual Disability/metabolism ; Male ; Membrane Proteins/metabolism ; Mice ; Rats
Czasopismo naukowe
Tytuł :
The cellular and molecular basis of in vivo synaptic plasticity in rodents.
Autorzy :
Cheyne JE; Department of Physiology and Centre for Brain Research, University of Auckland, Auckland, New Zealand.
Montgomery JM; Department of Physiology and Centre for Brain Research, University of Auckland, Auckland, New Zealand.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Jun 01; Vol. 318 (6), pp. C1264-C1283. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neuronal Plasticity*
Synaptic Transmission*
Brain/*metabolism
Electrical Synapses/*metabolism
Neurodevelopmental Disorders/*metabolism
Neurons/*metabolism
Animals ; Behavior, Animal ; Brain/growth & development ; Brain/pathology ; Disease Models, Animal ; Electrical Synapses/pathology ; Learning ; Long-Term Potentiation ; Models, Neurological ; Neurodevelopmental Disorders/pathology ; Neurodevelopmental Disorders/physiopathology ; Neurons/pathology ; Synaptic Potentials
Czasopismo naukowe
Tytuł :
Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms.
Autorzy :
Wang HY; Cellular and Molecular Synaptic Function Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, 904-0495, Japan.
Eguchi K; Cellular and Molecular Synaptic Function Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, 904-0495, Japan.; Molecular Neuroscience Group, Institute of Science and Technology Austria, Klosterneuburg, 3400, Austria.
Yamashita T; Department of Neuroscience II, Research Institute of Environmental Medicine, Nagoya University, Nagoya, 464-8601, Japan.
Takahashi T; Cellular and Molecular Synaptic Function Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, 904-0495, Japan .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 May 20; Vol. 40 (21), pp. 4103-4115. Date of Electronic Publication: 2020 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anesthetics, Inhalation/*administration & dosage
Brain Stem/*drug effects
Isoflurane/*administration & dosage
Neurons/*drug effects
Presynaptic Terminals/*drug effects
Synaptic Transmission/*drug effects
Animals ; Excitatory Postsynaptic Potentials/drug effects ; Exocytosis/drug effects ; Female ; Male ; Mice ; Patch-Clamp Techniques ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Aspects of excitatory/inhibitory synapses in multiple brain regions are correlated with levels of brain-derived neurotrophic factor/neurotrophin-3.
Autorzy :
Shinoda Y; Department of Environmental Health, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, 192-0392, Japan; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan; Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan. Electronic address: .
Sadakata T; Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan; Education and Research Support Center, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan.
Yagishita K; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Kinameri E; Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan.
Katoh-Semba R; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan; Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan.
Sano Y; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Furuichi T; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan; Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Feb 05; Vol. 509 (2), pp. 429-434. Date of Electronic Publication: 2018 Dec 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Brain-Derived Neurotrophic Factor/*genetics
Calcium-Binding Proteins/*genetics
Nerve Tissue Proteins/*genetics
Neurons/*metabolism
Neurotrophin 3/*genetics
Synapses/*genetics
Animals ; Brain-Derived Neurotrophic Factor/metabolism ; Calcium-Binding Proteins/deficiency ; Cerebellum/cytology ; Cerebellum/growth & development ; Cerebellum/metabolism ; Corpus Striatum/cytology ; Corpus Striatum/growth & development ; Corpus Striatum/metabolism ; Hippocampus/cytology ; Hippocampus/growth & development ; Hippocampus/metabolism ; Hypothalamus/cytology ; Hypothalamus/growth & development ; Hypothalamus/metabolism ; Male ; Mice ; Mice, Knockout ; Nerve Tissue Proteins/deficiency ; Neurons/cytology ; Neurotrophin 3/metabolism ; Organ Specificity ; Parietal Lobe/cytology ; Parietal Lobe/growth & development ; Parietal Lobe/metabolism ; Prefrontal Cortex/cytology ; Prefrontal Cortex/growth & development ; Prefrontal Cortex/metabolism ; Synapses/classification ; Synapses/metabolism ; Synaptic Transmission/genetics ; Vesicular Glutamate Transport Protein 1/genetics ; Vesicular Glutamate Transport Protein 1/metabolism ; Vesicular Inhibitory Amino Acid Transport Proteins/genetics ; Vesicular Inhibitory Amino Acid Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Area-Specific Synapse Structure in Branched Posterior Nucleus Axons Reveals a New Level of Complexity in Thalamocortical Networks.
Autorzy :
Rodriguez-Moreno J; Department of Anatomy and Neuroscience, School of Medicine, Autónoma de Madrid University, 28029 Madrid, Spain.
Porrero C; Department of Anatomy and Neuroscience, School of Medicine, Autónoma de Madrid University, 28029 Madrid, Spain.
Rollenhagen A; Institute of Neuroscience and Medicine INM-10, Research Centre Jülich GmbH, 52425 Jülich, Germany.
Rubio-Teves M; Department of Anatomy and Neuroscience, School of Medicine, Autónoma de Madrid University, 28029 Madrid, Spain.
Casas-Torremocha D; Department of Anatomy and Neuroscience, School of Medicine, Autónoma de Madrid University, 28029 Madrid, Spain.
Alonso-Nanclares L; Laboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Pozuelo de Alarcón, 28223 Madrid, Spain.
Yakoubi R; Institute of Neuroscience and Medicine INM-10, Research Centre Jülich GmbH, 52425 Jülich, Germany.
Santuy A; Laboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Pozuelo de Alarcón, 28223 Madrid, Spain.
Merchan-Pérez A; Laboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Pozuelo de Alarcón, 28223 Madrid, Spain.; CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, 28031 Madrid, Spain.; Departamento de Arquitectura y Tecnología de Sistemas Informáticos, Universidad Politécnica de Madrid. Boadilla del Monte, 28660 Madrid, Spain.
DeFelipe J; Laboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Pozuelo de Alarcón, 28223 Madrid, Spain.; Instituto Cajal, Consejo Superior de Investigaciones Científicas, Arce 37 28002, Madrid, Spain.; CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, 28031 Madrid, Spain.
Lübke JHR; Institute of Neuroscience and Medicine INM-10, Research Centre Jülich GmbH, 52425 Jülich, Germany.; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty RWTH University Hospital Aachen, 52074 Aachen, Germany, and.; JARA-Translational Brain Medicine, 52425 Jülich-Aachen, Germany.
Clasca F; Department of Anatomy and Neuroscience, School of Medicine, Autónoma de Madrid University, 28029 Madrid, Spain, .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Mar 25; Vol. 40 (13), pp. 2663-2679. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Axons/*physiology
Nerve Net/*physiology
Neurons/*physiology
Somatosensory Cortex/*physiology
Synapses/*physiology
Thalamus/*physiology
Animals ; Male ; Mice ; Mice, Inbred C57BL ; Neural Pathways/physiology ; Vibrissae/physiology
Czasopismo naukowe
Tytuł :
Capturing activated neurons and synapses.
Autorzy :
Choi JE; Center for Functional Connectomics, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
Kim J; Center for Functional Connectomics, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
Kim J; Center for Functional Connectomics, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea; Division of Bio-Medical Science & Technology, KIST-School, University of Science and Technology, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Neuroscience research [Neurosci Res] 2020 Mar; Vol. 152, pp. 25-34. Date of Electronic Publication: 2019 Dec 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Engineering/*methods
Neurons/*physiology
Synapses/*physiology
Animals ; Brain/physiology ; Humans
Czasopismo naukowe
Tytuł :
Assessing Neuron-Astrocyte Spatial Interactions Using the Neuron-Astrocyte Proximity Assay.
Autorzy :
Badia-Soteras A; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands.
Octeau JC; Department of Physiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Verheijen MHG; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands.
Khakh BS; Department of Physiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.; Department of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
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Źródło :
Current protocols in neuroscience [Curr Protoc Neurosci] 2020 Mar; Vol. 91 (1), pp. e91.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*cytology
Fluorescence Resonance Energy Transfer/*methods
Microscopy, Confocal/*methods
Neurons/*cytology
Animals ; Brain/cytology ; Cell Communication ; Cells, Cultured ; Dependovirus/genetics ; Female ; Genetic Vectors ; HEK293 Cells ; Humans ; Luminescent Proteins/analysis ; Luminescent Proteins/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Microinjections
Czasopismo naukowe
Tytuł :
Neurons, Glia, Extracellular Matrix and Neurovascular Unit: A Systems Biology Approach to the Complexity of Synaptic Plasticity in Health and Disease.
Autorzy :
De Luca C; Laboratory of Morphology of Neuronal Network, Department of Public Medicine, University of Campania 'Luigi Vanvitelli', 80138 Napoli, Italy.
Colangelo AM; Laboratory of Neuroscience 'R. Levi-Montalcini', Dept. of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.; SYSBIO Centre of Systems Biology ISBE.ITALY, University of Milano-Bicocca, 20126 Milano, Italy.
Virtuoso A; Laboratory of Morphology of Neuronal Network, Department of Public Medicine, University of Campania 'Luigi Vanvitelli', 80138 Napoli, Italy.
Alberghina L; SYSBIO Centre of Systems Biology ISBE.ITALY, University of Milano-Bicocca, 20126 Milano, Italy.
Papa M; Laboratory of Morphology of Neuronal Network, Department of Public Medicine, University of Campania 'Luigi Vanvitelli', 80138 Napoli, Italy.; SYSBIO Centre of Systems Biology ISBE.ITALY, University of Milano-Bicocca, 20126 Milano, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Feb 24; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuronal Plasticity*
Extracellular Matrix/*physiology
Neuroglia/*physiology
Neurons/*physiology
Synapses/*physiology
Systems Biology/*methods
Animals ; Central Nervous System/physiology ; Epilepsy/physiopathology ; Humans ; Neuroglia/cytology ; Neurons/cytology
Czasopismo naukowe
Tytuł :
Magnetic Domain Wall Based Synaptic and Activation Function Generator for Neuromorphic Accelerators.
Autorzy :
Siddiqui SA; Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Dutta S; Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Tang A; Department of Materials Science and Engineering , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Liu L; Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Ross CA; Department of Materials Science and Engineering , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Baldo MA; Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
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Źródło :
Nano letters [Nano Lett] 2020 Feb 12; Vol. 20 (2), pp. 1033-1040. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Magnetics*
Memory/*physiology
Neurons/*physiology
Synapses/*physiology
Energy Metabolism/physiology ; Humans
Czasopismo naukowe
Tytuł :
Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain.
Autorzy :
Lundgren JL; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
Vandermeulen L; Department of Pharmacological and Biomolecular Sciences, Universitá Degli Studi Di Milano, Milan, Italy.
Sandebring-Matton A; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
Ahmed S; Department of Diagnostic and Interventional Radiology, University Medical Center, Göttingen, Germany.
Winblad B; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
Di Luca M; Department of Pharmacological and Biomolecular Sciences, Universitá Degli Studi Di Milano, Milan, Italy.
Tjernberg LO; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden.
Marcello E; Department of Pharmacological and Biomolecular Sciences, Universitá Degli Studi Di Milano, Milan, Italy.
Frykman S; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, BioClinicum J9:20, Visionsgatan 4, 171 64, Solna, Sweden. .
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Źródło :
BMC neuroscience [BMC Neurosci] 2020 Feb 04; Vol. 21 (1), pp. 6. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ADAM10 Protein/*metabolism
Amyloid Precursor Protein Secretases/*metabolism
Amyloid beta-Protein Precursor/*metabolism
Aspartic Acid Endopeptidases/*metabolism
Brain/*metabolism
Membrane Proteins/*metabolism
Neurons/*metabolism
Synapses/*metabolism
Aged ; Aged, 80 and over ; Animals ; Female ; Humans ; Male ; Rats, Wistar ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the htt mouse model of Huntington's disease.
Autorzy :
McAdam RL; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, Scotland, UK.
Morton A; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, Scotland, UK.
Gordon SL; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, Scotland, UK.
Alterman JF; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Khvorova A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Cousin MA; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, Scotland, UK. Electronic address: .
Smillie KJ; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, Scotland, UK. Electronic address: .
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Źródło :
Neurobiology of disease [Neurobiol Dis] 2020 Feb; Vol. 134, pp. 104637. Date of Electronic Publication: 2019 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Corpus Striatum/*metabolism
Endocytosis/*physiology
Huntingtin Protein/*metabolism
Huntington Disease/*metabolism
Neurons/*metabolism
Synaptic Vesicles/*metabolism
Animals ; Disease Models, Animal ; Gene Knock-In Techniques ; Humans ; Huntingtin Protein/genetics ; Huntington Disease/genetics ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Assembly and maintenance of GABAergic and Glycinergic circuits in the mammalian nervous system.
Autorzy :
Gamlin CR; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Yu WQ; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Wong ROL; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Hoon M; Department of Biological Structure, University of Washington, Seattle, WA, USA. .; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA. .
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Źródło :
Neural development [Neural Dev] 2018 Jun 07; Vol. 13 (1), pp. 12. Date of Electronic Publication: 2018 Jun 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Glycine/*metabolism
Nerve Net/*physiology
Nervous System/*cytology
Neurons/*physiology
gamma-Aminobutyric Acid/*metabolism
Animals ; Humans ; Mammals
Czasopismo naukowe
Tytuł :
Cell adhesion and matricellular support by astrocytes of the tripartite synapse.
Autorzy :
Hillen AEJ; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands; Department of Pediatrics/Child Neurology, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Burbach JPH; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
Hol EM; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands; Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, 1098 XH Amsterdam, The Netherlands; Department of Neuroimmunology, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands. Electronic address: .
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Źródło :
Progress in neurobiology [Prog Neurobiol] 2018 Jun - Aug; Vol. 165-167, pp. 66-86. Date of Electronic Publication: 2018 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Astrocytes/*physiology
Cell Adhesion Molecules/*metabolism
Extracellular Matrix/*physiology
Membrane Proteins/*metabolism
Neurons/*physiology
Synapses/*physiology
Synaptic Transmission/*physiology
Animals ; Astrocytes/metabolism ; Humans
Czasopismo naukowe
Tytuł :
LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.
Autorzy :
Sclip A; Department of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, United States.
Südhof TC; Department of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, United States.
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Źródło :
ELife [Elife] 2020 Jan 27; Vol. 9. Date of Electronic Publication: 2020 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Neurons/*metabolism
Receptor-Like Protein Tyrosine Phosphatases, Class 2/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Synapses/*metabolism
Animals ; Female ; Hippocampus/metabolism ; Hippocampus/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptor-Like Protein Tyrosine Phosphatases, Class 2/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
Ocular Dominance Plasticity in Binocular Primary Visual Cortex Does Not Require C1q.
Autorzy :
Welsh CA; F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115.
Stephany CÉ; F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115.
Sapp RW; Departments of Biology and Neurobiology, and Bio-X, James H. Clark Center, Stanford University, Stanford, California 94305.
Stevens B; F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, .; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, and.; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts 02115.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jan 22; Vol. 40 (4), pp. 769-783. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Complement C1q/*metabolism
Dominance, Ocular/*physiology
Neuronal Plasticity/*physiology
Neurons/*metabolism
Visual Cortex/*metabolism
Animals ; Complement C1q/genetics ; Dendrites/metabolism ; Dendritic Spines/metabolism ; Mice ; Mice, Knockout ; Synapses/metabolism
Czasopismo naukowe

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