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Tytuł:
Retrograde endocannabinoid signaling at inhibitory synapses in vivo.
Autorzy:
Dudok B; Departments of Neurology and Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Fan LZ; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Farrell JS; Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.; F.M. Kirby Neurobiology Center and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Malhotra S; Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Homidan J; Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Kim DK; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Wenardy C; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Ramakrishnan C; Cracking the Neural Code (CNC) Program, Stanford University, Stanford, CA 94305, USA.
Li Y; State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Deisseroth K; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford, CA 94305, USA.
Soltesz I; Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar; Vol. 383 (6686), pp. 967-970. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Endocannabinoids*/physiology
Synapses*/physiology
Synaptic Transmission*
CA1 Region, Hippocampal*/physiology
Inhibitory Postsynaptic Potentials*
Animals ; Mice ; Neuronal Plasticity/physiology ; Calcium Signaling ; Receptor, Cannabinoid, CB1/genetics ; Receptor, Cannabinoid, CB1/physiology ; Male ; Female ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GluD1 binds GABA and controls inhibitory plasticity.
Autorzy:
Piot L; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Heroven C; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Bossi S; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Zamith J; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Malinauskas T; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Johnson C; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Wennagel D; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Stroebel D; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Charrier C; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Aricescu AR; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Mony L; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
Paoletti P; Institut de Biologie de l'ENS (IBENS), Ecole Normale Supérieure, Université PSL, CNRS, INSERM, F-75005 Paris, France.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Dec 22; Vol. 382 (6677), pp. 1389-1394. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
gamma-Aminobutyric Acid*/metabolism
Neuronal Plasticity*
Receptors, GABA*/metabolism
Synaptic Transmission*
Neural Inhibition*
Animals ; Mice ; Glutamate Dehydrogenase/metabolism ; Hippocampus/metabolism ; Synapses/physiology ; Mice, Knockout ; Racemases and Epimerases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Presynaptic Ube3a E3 ligase promotes synapse elimination through down-regulation of BMP signaling.
Autorzy:
Furusawa K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Ishii K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Tsuji M; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Tokumitsu N; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Hasegawa E; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Emoto K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Sep 15; Vol. 381 (6663), pp. 1197-1205. Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Angelman Syndrome*/enzymology
Angelman Syndrome*/genetics
Autism Spectrum Disorder*/enzymology
Autism Spectrum Disorder*/genetics
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Synaptic Transmission*
Ubiquitin-Protein Ligases*/genetics
Ubiquitin-Protein Ligases*/metabolism
Drosophila melanogaster*
Animals ; Down-Regulation ; Synapses/enzymology ; Synapses/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigating the ability of astrocytes to drive neural network synchrony.
Autorzy:
Handy G; Departments of Neurobiology and Statistics, University of Chicago, Chicago, Illinois, United States of America.; Grossman Center for Quantitative Biology and Human Behavior, University of Chicago, Chicago, Illinois, United States of America.
Borisyuk A; Department of Mathematics, University of Utah, Salt Lake City, Utah, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Aug 09; Vol. 19 (8), pp. e1011290. Date of Electronic Publication: 2023 Aug 09 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes*/metabolism
Synaptic Transmission*/physiology
Animals ; Neurons/physiology ; Synapses/physiology ; Neural Networks, Computer ; Mammals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bidirectional modulation of evoked synaptic transmission by pulsed infrared light.
Autorzy:
Zhu X; Department of Biomedical Engineering, Boston University, 44 Cummington Mall, Boston, MA, 02215, USA.; Photonics Center, Boston University, 8 Saint Mary's Street, Boston, MA, 02215, USA.; Neurophotonics Center, Boston University, 24 Cummington Mall, Boston, MA, 02215, USA.
Lin JW; Department of Biology, Boston University, 5 Cummington Mall, Boston, MA, 02215, USA.
Sander MY; Department of Biomedical Engineering, Boston University, 44 Cummington Mall, Boston, MA, 02215, USA. .; Photonics Center, Boston University, 8 Saint Mary's Street, Boston, MA, 02215, USA. .; Neurophotonics Center, Boston University, 24 Cummington Mall, Boston, MA, 02215, USA. .; Department of Electrical and Computer Engineering, Boston University, 8 Saint Mary's Street, Boston, MA, 02215, USA. .; Division of Materials Science and Engineering, Boston University, 15 Saint Mary's Street, Brookline, MA, 02446, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 20; Vol. 12 (1), pp. 14196. Date of Electronic Publication: 2022 Aug 20.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Synapses*/physiology
Synaptic Transmission*/physiology
Action Potentials/physiology ; Excitatory Postsynaptic Potentials/physiology ; Neuromuscular Junction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigating the Role of GABA in Neural Development and Disease Using Mice Lacking GAD67 or VGAT Genes.
Autorzy:
Bolneo E; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane 4072, Australia.
Chau PYS; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane 4072, Australia.
Noakes PG; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.
Bellingham MC; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane 4072, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 19; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Synapses*/metabolism
Synaptic Transmission*/genetics
Animals ; Glutamate Decarboxylase/genetics ; Glutamate Decarboxylase/metabolism ; Mammals/metabolism ; Mice ; Neurogenesis ; Neurons/metabolism ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel Role for UNC119 as an Enhancer of Synaptic Transmission.
Autorzy:
Fehlhaber KE; Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.
Majumder A; Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, USA.
Boyd KK; Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, USA.
Griffis KG; Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.
Artemyev NO; Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, USA.; Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA 52242, USA.
Fain GL; Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.
Sampath AP; Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 30; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Synaptic Transmission*/physiology
Transducin*/metabolism
Animals ; Mice ; Glutamates/metabolism ; Mammals/metabolism ; Retina/metabolism ; Synapses/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synaptic modifications transform neural networks to function without oxygen.
Autorzy:
Amaral-Silva L; Division of Biological Sciences, The University of Missouri, Columbia, USA. .
Santin JM; Division of Biological Sciences, The University of Missouri, Columbia, USA. .
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Źródło:
BMC biology [BMC Biol] 2023 Mar 16; Vol. 21 (1), pp. 54. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Oxygen*/metabolism
Synaptic Transmission*/physiology
Animals ; Neurons/physiology ; Synapses ; Neural Networks, Computer ; Hypoxia ; Mammals ; Neuronal Plasticity/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synapses: The Brain's Energy-Demanding Sites.
Autorzy:
Faria-Pereira A; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.
Morais VA; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 26; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Synapses*/metabolism
Synaptic Transmission*/physiology
Animals ; Brain/metabolism ; Energy Metabolism/physiology ; Mammals ; Presynaptic Terminals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Topographical distance between presynaptic Ca sensors contributes to differential facilitatory actions of roscovitine on neurotransmitter release at cerebellar glutamatergic and GABAergic synapses.
Autorzy:
Satake SI; Brain Research Support Center, National Institute for Physiological Sciences (NIPS), Okazaki, Japan.; School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), Okazaki, Japan.
Konishi S; Department of Neurophysiology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki, Japan.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2021 Nov; Vol. 54 (9), pp. 7048-7062. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Synapses*
Synaptic Transmission*
Cerebellum/*drug effects
Roscovitine/*pharmacology
Animals ; Calcium Channels, N-Type ; Cerebellum/metabolism ; Glutamic Acid ; Neurotransmitter Agents ; Presynaptic Terminals/drug effects ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Lithium causes differential effects on postsynaptic stability in normal and denervated neuromuscular synapses.
Autorzy:
Zelada D; Neuromuscular Studies Laboratory (NeSt Lab), Department of Cell Biology, CMA Bio-Bio, Facultad de Ciencias Biológicas, Universidad de Concepción, Casilla 160-C, Concepción, Chile.
Barrantes FJ; Pontificia Universidad Católica Argentina (UCA)-Scientific and Technological Research Council of Argentina (CONICET), Buenos Aires, Argentina.
Henríquez JP; Neuromuscular Studies Laboratory (NeSt Lab), Department of Cell Biology, CMA Bio-Bio, Facultad de Ciencias Biológicas, Universidad de Concepción, Casilla 160-C, Concepción, Chile. .
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 26; Vol. 11 (1), pp. 17285. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lithium Chloride/*pharmacology
Neuromuscular Junction/*drug effects
Synapses/*drug effects
Synaptic Potentials/*drug effects
Synaptic Transmission/*drug effects
Synaptic Transmission/*physiology
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Denervation/methods ; Mice ; Microscopy, Fluorescence/methods ; Neuromuscular Junction/physiology ; Neuromuscular Junction/surgery ; Protein Transport/drug effects ; Receptors, Nicotinic/genetics ; Receptors, Nicotinic/metabolism ; Synapses/metabolism ; Synapses/physiology ; Synaptic Potentials/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanisms of endocannabinoid transport in the brain.
Autorzy:
Kaczocha M; Department of Anesthesiology, Stony Brook University, Stony Brook, New York, USA.; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA.
Haj-Dahmane S; Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.; Neuroscience Program, University at Buffalo, Buffalo, New York, USA.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2022 Sep; Vol. 179 (17), pp. 4300-4310. Date of Electronic Publication: 2021 May 27.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Endocannabinoids*
Synaptic Transmission*
Brain ; Cannabinoid Receptor Modulators ; Receptors, Cannabinoid ; Synapses
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Unbalanced Synaptic Transmission: Cause or Consequence of the Amyloid Oligomers Neurotoxicity?
Autorzy:
Sciaccaluga M; Neurology Clinic, Department of Medicine and Surgery, University of Perugia, Santa Maria della Misericordia Hospital, 06132 Perugia, Italy.
Megaro A; Neurology Clinic, Department of Medicine and Surgery, University of Perugia, Santa Maria della Misericordia Hospital, 06132 Perugia, Italy.
Bellomo G; Neurology Clinic, Department of Medicine and Surgery, University of Perugia, Santa Maria della Misericordia Hospital, 06132 Perugia, Italy.
Ruffolo G; Department of Physiology and Pharmacology, Istituto Pasteur-Fondazione Cenci Bolognetti, University of Rome Sapienza, 00185 Rome, Italy.; IRCCS San Raffaele Pisana, 00166 Rome, Italy.
Romoli M; Neurology Unit, Rimini 'Infermi' Hospital-AUSL Romagna, 47923 Rimini, Italy.
Palma E; Department of Physiology and Pharmacology, Istituto Pasteur-Fondazione Cenci Bolognetti, University of Rome Sapienza, 00185 Rome, Italy.
Costa C; Neurology Clinic, Department of Medicine and Surgery, University of Perugia, Santa Maria della Misericordia Hospital, 06132 Perugia, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 01; Vol. 22 (11). Date of Electronic Publication: 2021 Jun 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease/*genetics
Amyloid beta-Peptides/*genetics
Synapses/*genetics
Synaptic Transmission/*genetics
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/adverse effects ; Amyloid beta-Peptides/ultrastructure ; Amyloidogenic Proteins/adverse effects ; Amyloidogenic Proteins/genetics ; Animals ; Humans ; Peptide Fragments/genetics ; Peptide Fragments/metabolism ; Protein Multimerization/genetics ; Synapses/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Local connectivity and synaptic dynamics in mouse and human neocortex.
Autorzy:
Campagnola L; Allen Institute for Brain Science, Seattle, WA, USA.
Seeman SC; Allen Institute for Brain Science, Seattle, WA, USA.
Chartrand T; Allen Institute for Brain Science, Seattle, WA, USA.
Kim L; Allen Institute for Brain Science, Seattle, WA, USA.
Hoggarth A; Allen Institute for Brain Science, Seattle, WA, USA.
Gamlin C; Allen Institute for Brain Science, Seattle, WA, USA.
Ito S; Allen Institute for Brain Science, Seattle, WA, USA.
Trinh J; Allen Institute for Brain Science, Seattle, WA, USA.
Davoudian P; Allen Institute for Brain Science, Seattle, WA, USA.
Radaelli C; Allen Institute for Brain Science, Seattle, WA, USA.
Kim MH; Allen Institute for Brain Science, Seattle, WA, USA.
Hage T; Allen Institute for Brain Science, Seattle, WA, USA.
Braun T; Byte Physics, Berlin, Germany.
Alfiler L; Allen Institute for Brain Science, Seattle, WA, USA.
Andrade J; Allen Institute for Brain Science, Seattle, WA, USA.
Bohn P; Allen Institute for Brain Science, Seattle, WA, USA.
Dalley R; Allen Institute for Brain Science, Seattle, WA, USA.
Henry A; Allen Institute for Brain Science, Seattle, WA, USA.
Kebede S; Allen Institute for Brain Science, Seattle, WA, USA.
Alice M; Allen Institute for Brain Science, Seattle, WA, USA.
Sandman D; Allen Institute for Brain Science, Seattle, WA, USA.
Williams G; Allen Institute for Brain Science, Seattle, WA, USA.
Larsen R; Allen Institute for Brain Science, Seattle, WA, USA.
Teeter C; Allen Institute for Brain Science, Seattle, WA, USA.
Daigle TL; Allen Institute for Brain Science, Seattle, WA, USA.
Berry K; Allen Institute for Brain Science, Seattle, WA, USA.
Dotson N; Allen Institute for Brain Science, Seattle, WA, USA.
Enstrom R; Allen Institute for Brain Science, Seattle, WA, USA.
Gorham M; Allen Institute for Brain Science, Seattle, WA, USA.
Hupp M; Allen Institute for Brain Science, Seattle, WA, USA.
Dingman Lee S; Allen Institute for Brain Science, Seattle, WA, USA.
Ngo K; Allen Institute for Brain Science, Seattle, WA, USA.
Nicovich PR; Allen Institute for Brain Science, Seattle, WA, USA.
Potekhina L; Allen Institute for Brain Science, Seattle, WA, USA.
Ransford S; Allen Institute for Brain Science, Seattle, WA, USA.
Gary A; Allen Institute for Brain Science, Seattle, WA, USA.
Goldy J; Allen Institute for Brain Science, Seattle, WA, USA.
McMillen D; Allen Institute for Brain Science, Seattle, WA, USA.
Pham T; Allen Institute for Brain Science, Seattle, WA, USA.
Tieu M; Allen Institute for Brain Science, Seattle, WA, USA.
Siverts L; Allen Institute for Brain Science, Seattle, WA, USA.
Walker M; Allen Institute for Brain Science, Seattle, WA, USA.
Farrell C; Allen Institute for Brain Science, Seattle, WA, USA.
Schroedter M; Allen Institute for Brain Science, Seattle, WA, USA.
Slaughterbeck C; Allen Institute for Brain Science, Seattle, WA, USA.
Cobb C; The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle, WA, USA.
Ellenbogen R; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.
Gwinn RP; Epilepsy Surgery and Functional Neurosurgery, Swedish Neuroscience Institute, Seattle, WA, USA.
Keene CD; Department of Pathology, University of Washington, Seattle, WA, USA.
Ko AL; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.; Regional Epilepsy Center at Harborview Medical Center, Seattle, WA, USA.
Ojemann JG; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.; Regional Epilepsy Center at Harborview Medical Center, Seattle, WA, USA.
Silbergeld DL; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.
Carey D; Allen Institute for Brain Science, Seattle, WA, USA.
Casper T; Allen Institute for Brain Science, Seattle, WA, USA.
Crichton K; Allen Institute for Brain Science, Seattle, WA, USA.
Clark M; Allen Institute for Brain Science, Seattle, WA, USA.
Dee N; Allen Institute for Brain Science, Seattle, WA, USA.
Ellingwood L; Allen Institute for Brain Science, Seattle, WA, USA.
Gloe J; Allen Institute for Brain Science, Seattle, WA, USA.
Kroll M; Allen Institute for Brain Science, Seattle, WA, USA.
Sulc J; Allen Institute for Brain Science, Seattle, WA, USA.
Tung H; Allen Institute for Brain Science, Seattle, WA, USA.
Wadhwani K; Allen Institute for Brain Science, Seattle, WA, USA.
Brouner K; Allen Institute for Brain Science, Seattle, WA, USA.
Egdorf T; Allen Institute for Brain Science, Seattle, WA, USA.
Maxwell M; Allen Institute for Brain Science, Seattle, WA, USA.
McGraw M; Allen Institute for Brain Science, Seattle, WA, USA.
Pom CA; Allen Institute for Brain Science, Seattle, WA, USA.
Ruiz A; Allen Institute for Brain Science, Seattle, WA, USA.
Bomben J; Allen Institute for Brain Science, Seattle, WA, USA.
Feng D; Allen Institute for Brain Science, Seattle, WA, USA.
Hejazinia N; Allen Institute for Brain Science, Seattle, WA, USA.
Shi S; Allen Institute for Brain Science, Seattle, WA, USA.
Szafer A; Allen Institute for Brain Science, Seattle, WA, USA.
Wakeman W; Allen Institute for Brain Science, Seattle, WA, USA.
Phillips J; Allen Institute for Brain Science, Seattle, WA, USA.
Bernard A; Allen Institute for Brain Science, Seattle, WA, USA.
Esposito L; Allen Institute for Brain Science, Seattle, WA, USA.
D'Orazi FD; Allen Institute for Brain Science, Seattle, WA, USA.
Sunkin S; Allen Institute for Brain Science, Seattle, WA, USA.
Smith K; Allen Institute for Brain Science, Seattle, WA, USA.
Tasic B; Allen Institute for Brain Science, Seattle, WA, USA.
Arkhipov A; Allen Institute for Brain Science, Seattle, WA, USA.
Sorensen S; Allen Institute for Brain Science, Seattle, WA, USA.
Lein E; Allen Institute for Brain Science, Seattle, WA, USA.
Koch C; Allen Institute for Brain Science, Seattle, WA, USA.
Murphy G; Allen Institute for Brain Science, Seattle, WA, USA.
Zeng H; Allen Institute for Brain Science, Seattle, WA, USA.
Jarsky T; Allen Institute for Brain Science, Seattle, WA, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Mar 11; Vol. 375 (6585), pp. eabj5861. Date of Electronic Publication: 2022 Mar 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Neural Pathways*
Synaptic Transmission*
Neocortex/*physiology
Neurons/*physiology
Synapses/*physiology
Adult ; Animals ; Datasets as Topic ; Excitatory Postsynaptic Potentials ; Female ; Humans ; Inhibitory Postsynaptic Potentials ; Male ; Mice ; Mice, Transgenic ; Models, Neurological ; Neocortex/cytology ; Temporal Lobe/cytology ; Temporal Lobe/physiology ; Visual Cortex/cytology ; Visual Cortex/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A behavioural correlate of the synaptic eligibility trace in the nucleus accumbens.
Autorzy:
Yamaguchi K; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; Department of Psychology, Waseda University, Shinjuku-ku, Tokyo, Japan.
Maeda Y; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Sawada T; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Iino Y; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Tajiri M; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Nakazato R; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Ishii S; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; Graduate School of Informatics, Kyoto University, Yoshida-Honmachi, Kyoto, Japan.
Kasai H; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Yagishita S; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, Faculty of Medicine Bldg, The University of Tokyo, 1 #NC207, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. .; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 04; Vol. 12 (1), pp. 1921. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Behavior, Animal*
Reward*
Synaptic Transmission*
Nucleus Accumbens/*physiology
Synapses/*physiology
Acoustic Stimulation ; Animals ; Conditioning, Classical ; Cues ; Drinking ; Male ; Mice, Transgenic ; Neuronal Plasticity ; Optogenetics ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Voltage-gated calcium channel nanodomains: molecular composition and function.
Autorzy:
Gandini MA; Department of Physiology and Pharmacology, Alberta Children's Hospital Research Institute, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, AB, Canada.
Zamponi GW; Department of Physiology and Pharmacology, Alberta Children's Hospital Research Institute, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, AB, Canada.
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Źródło:
The FEBS journal [FEBS J] 2022 Feb; Vol. 289 (3), pp. 614-633. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Calcium Channels/*genetics
Calcium-Binding Proteins/*genetics
Synapses/*genetics
Synaptic Transmission/*genetics
Calcium/metabolism ; Calcium Signaling/genetics ; Humans ; Neurons/metabolism ; Presynaptic Terminals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Developmental Formation of the GABAergic and Glycinergic Networks in the Mouse Spinal Cord.
Autorzy:
Shimizu-Okabe C; Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.
Kobayashi S; Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.
Kim J; Department of Anatomy, Kosin University College of Medicine, Busan 49267, Korea.
Kosaka Y; Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.
Sunagawa M; Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.
Okabe A; Department of Nutritional Science, Faculty of Health and Welfare, Seinan Jo Gakuin University, Fukuoka 803-0835, Japan.
Takayama C; Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 13; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Signal Transduction*
Synaptic Transmission*
GABAergic Neurons/*metabolism
Glycine/*metabolism
Receptors, Glycine/*metabolism
Spinal Cord/*metabolism
gamma-Aminobutyric Acid/*metabolism
Animals ; Anterior Horn Cells/metabolism ; Astrocytes/metabolism ; Axons/metabolism ; Biomarkers ; Ganglia, Spinal/metabolism ; Mice ; Spinal Cord/cytology ; Synapses/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses.
Autorzy:
Han KA; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.; Core Protein Resources Center, DGIST, 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.
Lee HY; Department of Physiology and Neuroscience, Dental Research Institute, Seoul National University School of Dentistry, Seoul, 03080, South Korea.
Lim D; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.
Shin J; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.
Yoon TH; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.
Liu X; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06510, USA.
Um JW; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.; Core Protein Resources Center, DGIST, 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea.
Choi SY; Department of Physiology and Neuroscience, Dental Research Institute, Seoul National University School of Dentistry, Seoul, 03080, South Korea.
Ko J; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno Jungangdae-Ro, Hyeonpoong-Eup, Dalseong-Gun, Daegu, 42988, South Korea. .
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Źródło:
Molecular brain [Mol Brain] 2020 Jun 17; Vol. 13 (1), pp. 94. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hippocampus/*enzymology
Hippocampus/*physiology
Receptor-Like Protein Tyrosine Phosphatases, Class 2/*metabolism
Synapses/*physiology
Synaptic Transmission/*physiology
Animals ; HEK293 Cells ; Hippocampus/ultrastructure ; Humans ; Mice, Knockout ; Neural Inhibition/physiology ; Neurons/metabolism ; Neurotransmitter Agents/metabolism ; Pyramidal Cells/metabolism ; Receptor-Like Protein Tyrosine Phosphatases, Class 2/deficiency ; Synapses/ultrastructure ; Synaptic Vesicles/metabolism ; Synaptic Vesicles/ultrastructure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Strong preference for autaptic self-connectivity of neocortical PV interneurons facilitates their tuning to γ-oscillations.
Autorzy:
Deleuze C; ICM-Institut du Cerveau et de la Moelle épinière, Inserm U1127, CNRS UMR 7225, Sorbonne Université, Paris, France.
Bhumbra GS; Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Pazienti A; European Brain Research Institute, Rome, Italy.
Lourenço J; ICM-Institut du Cerveau et de la Moelle épinière, Inserm U1127, CNRS UMR 7225, Sorbonne Université, Paris, France.
Mailhes C; ICM-Institut du Cerveau et de la Moelle épinière, Inserm U1127, CNRS UMR 7225, Sorbonne Université, Paris, France.
Aguirre A; ICM-Institut du Cerveau et de la Moelle épinière, Inserm U1127, CNRS UMR 7225, Sorbonne Université, Paris, France.
Beato M; Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.
Bacci A; ICM-Institut du Cerveau et de la Moelle épinière, Inserm U1127, CNRS UMR 7225, Sorbonne Université, Paris, France.
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Źródło:
PLoS biology [PLoS Biol] 2019 Sep 04; Vol. 17 (9), pp. e3000419. Date of Electronic Publication: 2019 Sep 04 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Synapses*
Synaptic Transmission*
Interneurons/*physiology
Neocortex/*physiology
Animals ; Female ; Male ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nicotinic activity layer specifically modulates synaptic potentiation in the mouse insular cortex.
Autorzy:
Toyoda H; Department of Oral Physiology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, 565-0871, Japan.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2019 Aug; Vol. 50 (3), pp. 2211-2223. Date of Electronic Publication: 2018 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebral Cortex/*physiology
Nicotine/*pharmacology
Receptors, Nicotinic/*physiology
Synapses/*physiology
Synaptic Transmission/*physiology
Acetylcholine/pharmacology ; Animals ; Cerebral Cortex/cytology ; Cerebral Cortex/drug effects ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Nicotinic Agonists/pharmacology ; Synapses/drug effects ; Synaptic Transmission/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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