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Wyszukujesz frazę ""Synaptic Transmission"" wg kryterium: Temat


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Tytuł :
Topographical distance between presynaptic Ca sensors contributes to differential facilitatory actions of roscovitine on neurotransmitter release at cerebellar glutamatergic and GABAergic synapses.
Autorzy :
Satake SI; Brain Research Support Center, National Institute for Physiological Sciences (NIPS), Okazaki, Japan.; School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), Okazaki, Japan.
Konishi S; Department of Neurophysiology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki, Japan.
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Źródło :
The European journal of neuroscience [Eur J Neurosci] 2021 Nov; Vol. 54 (9), pp. 7048-7062. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Synapses*
Synaptic Transmission*
Animals ; Cerebellum ; Neurotransmitter Agents ; Presynaptic Terminals ; Rats ; Roscovitine
Czasopismo naukowe
Tytuł :
The generation of cortical novelty responses through inhibitory plasticity.
Autorzy :
Schulz A; Max Planck Institute for Brain Research, Frankfurt, Germany.; Technical University of Munich, Department of Electrical and Computer Engineering, Munich, Germany.
Miehl C; Max Planck Institute for Brain Research, Frankfurt, Germany.; Technical University of Munich, School of Life Sciences, Freising, Germany.
Berry MJ 2nd; Princeton University, Princeton Neuroscience Institute, Princeton, United States.
Gjorgjieva J; Max Planck Institute for Brain Research, Frankfurt, Germany.; Technical University of Munich, School of Life Sciences, Freising, Germany.
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Źródło :
ELife [Elife] 2021 Oct 14; Vol. 10. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Behavior, Animal*
Exploratory Behavior*
Models, Neurological*
Neural Inhibition*
Neuronal Plasticity*
Synaptic Transmission*
Cerebral Cortex/*physiology
Action Potentials ; Animals ; Computer Simulation ; Mice ; Periodicity ; Reaction Time ; Signal Detection, Psychological ; Time Factors
Czasopismo naukowe
Tytuł :
Clonazepam attenuates neurobehavioral abnormalities in offspring exposed to maternal immune activation by enhancing GABAergic neurotransmission.
Autorzy :
Yang Y; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: .
Wang B; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Zhong Z; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Chen H; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Ding W; School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Hoi MPM; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114711. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Clonazepam/*therapeutic use
GABA Modulators/*therapeutic use
GABAergic Neurons/*immunology
Mental Disorders/*immunology
Prenatal Exposure Delayed Effects/*immunology
Synaptic Transmission/*immunology
Animals ; Clonazepam/pharmacology ; Female ; GABA Modulators/pharmacology ; GABA-A Receptor Agonists/pharmacology ; GABA-A Receptor Agonists/therapeutic use ; GABAergic Neurons/chemistry ; GABAergic Neurons/drug effects ; Male ; Mental Disorders/chemically induced ; Mental Disorders/prevention & control ; Mice ; Mice, Inbred C57BL ; NAV1.1 Voltage-Gated Sodium Channel/biosynthesis ; NAV1.1 Voltage-Gated Sodium Channel/immunology ; Poly I-C/toxicity ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/immunology ; Pregnancy ; Prenatal Exposure Delayed Effects/chemically induced ; Prenatal Exposure Delayed Effects/prevention & control ; Receptors, GABA-A/immunology ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Potential mechanism of GABA secretion in response to the activation of GluK1-containing kainate receptors.
Autorzy :
Maiorov SA; Institute of Cell Biophysics of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290, Pushchino, Russia.
Zinchenko VP; Institute of Cell Biophysics of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290, Pushchino, Russia.
Gaidin SG; Institute of Cell Biophysics of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290, Pushchino, Russia. Electronic address: .
Kosenkov AM; Institute of Cell Biophysics of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290, Pushchino, Russia. Electronic address: .
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Źródło :
Neuroscience research [Neurosci Res] 2021 Oct; Vol. 171, pp. 27-33. Date of Electronic Publication: 2021 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Kainic Acid*/metabolism
Synaptic Transmission*
Neurons/metabolism ; Synapses/metabolism ; gamma-Aminobutyric Acid
Czasopismo naukowe
Tytuł :
Receptor-Dependent and Independent Regulation of Voltage-Gated Ca -Permeable Channels by Endocannabinoids in the Brain.
Autorzy :
Boczek T; Department of Molecular Neurochemistry, Faculty of Health Sciences, Medical University of Lodz, 92215 Lodz, Poland.
Zylinska L; Department of Molecular Neurochemistry, Faculty of Health Sciences, Medical University of Lodz, 92215 Lodz, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 29; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Synaptic Transmission*
Brain/*metabolism
Calcium/*metabolism
Calcium Channels/*metabolism
Endocannabinoids/*metabolism
Animals ; Humans ; Receptor, Cannabinoid, CB1/metabolism ; Receptor, Cannabinoid, CB2/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis.
Autorzy :
Jiang ZJ; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.
Li W; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.
Yao LH; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.; School of Life Science, Jiangxi Science & Technology Normal University, Nanchang, China.
Saed B; Department of Chemistry, University of Illinois at Chicago, Chicago, United States.
Rao Y; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.
Grewe BS; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.
McGinley A; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.
Varga K; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.; Department of Biological Sciences, University of North Texas at Dallas, Dallas, United States.
Alford S; Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, United States.
Hu YS; Department of Chemistry, University of Illinois at Chicago, Chicago, United States.
Gong LW; Department of Biological Sciences, University of Illinois at Chicago, Chicago, United States.
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Źródło :
ELife [Elife] 2021 Sep 27; Vol. 10. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Endocytosis*
Neural Inhibition*
Neuronal Plasticity*
Synaptic Transmission*
Neurons/*metabolism
Synaptic Vesicles/*metabolism
TRPM Cation Channels/*metabolism
Animals ; Calcium/metabolism ; Calcium Signaling ; Chromaffin Cells/metabolism ; Excitatory Postsynaptic Potentials ; Female ; HEK293 Cells ; Humans ; Inhibitory Postsynaptic Potentials ; Kinetics ; Male ; Mice, Knockout ; Synaptic Vesicles/genetics ; TRPM Cation Channels/genetics
Czasopismo naukowe
Tytuł :
Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits.
Autorzy :
Palacios-Filardo J; Center for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Bristol, UK.
Udakis M; Center for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Bristol, UK.
Brown GA; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.; OMass Therapeutics Ltd, The Schrödinger Building, Oxford, UK.
Tehan BG; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.; OMass Therapeutics Ltd, The Schrödinger Building, Oxford, UK.
Congreve MS; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.
Nathan PJ; Department of Psychiatry, University of Cambridge, Cambridge, UK.
Brown AJH; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.
Mellor JR; Center for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Bristol, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 16; Vol. 12 (1), pp. 5475. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholine/*metabolism
CA1 Region, Hippocampal/*physiology
Entorhinal Cortex/*physiology
Excitatory Postsynaptic Potentials/*physiology
Feedback, Physiological/*physiology
Synaptic Transmission/*physiology
Animals ; CA1 Region, Hippocampal/cytology ; Carbachol/pharmacology ; Cholinergic Agonists/pharmacology ; Entorhinal Cortex/cytology ; Excitatory Postsynaptic Potentials/drug effects ; Feedback, Physiological/drug effects ; Interneurons/metabolism ; Interneurons/physiology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Patch-Clamp Techniques ; Pyramidal Cells/metabolism ; Pyramidal Cells/physiology ; Receptor, Muscarinic M3/genetics ; Receptor, Muscarinic M3/metabolism ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Optimal plasticity for memory maintenance during ongoing synaptic change.
Autorzy :
Raman DV; Department of Engineering, University of Cambridge, Cambridge, United Kingdom.
O'Leary T; Department of Engineering, University of Cambridge, Cambridge, United Kingdom.
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Źródło :
ELife [Elife] 2021 Sep 14; Vol. 10. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Behavior, Animal*
Memory*
Models, Neurological*
Neuronal Plasticity*
Synaptic Transmission*
Brain/*physiology
Neural Pathways/*physiology
Neurons/*physiology
Animals ; Brain/cytology ; Computer Simulation ; Humans ; Mice ; Neural Pathways/cytology ; Rats ; Time Factors
Czasopismo naukowe
Tytuł :
Synaptic mechanism underlying serotonin modulation of transition to cocaine addiction.
Autorzy :
Li Y; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Simmler LD; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Van Zessen R; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Flakowski J; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA.
Wan JX; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Deng F; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Li YL; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Nautiyal KM; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA.
Pascoli V; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.
Lüscher C; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA.; Clinic of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, CH-1211 Geneva, Switzerland.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Sep 10; Vol. 373 (6560), pp. 1252-1256. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Synaptic Transmission*
Cocaine-Related Disorders/*metabolism
Receptor, Serotonin, 5-HT1B/*metabolism
Serotonin/*metabolism
Animals ; Cocaine/administration & dosage ; Cocaine-Related Disorders/genetics ; Dopamine/metabolism ; Gene Knock-In Techniques ; Mice ; Mice, Knockout ; Optogenetics ; Receptor, Serotonin, 5-HT1B/deficiency ; Serotonin Plasma Membrane Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Synaptic Dysfunction in Multiple Sclerosis: A Red Thread from Inflammation to Network Disconnection.
Autorzy :
Bellingacci L; Section of Neurology, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Mancini A; Section of Neurology, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Gaetani L; Section of Neurology, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Tozzi A; Section of Physiology and Biochemistry, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Parnetti L; Section of Neurology, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
Di Filippo M; Section of Neurology, Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 09; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Susceptibility*
Synaptic Transmission*
Multiple Sclerosis/*etiology
Multiple Sclerosis/*metabolism
Synapses/*metabolism
Animals ; Biomarkers ; Disease Models, Animal ; Disease Progression ; Encephalomyelitis, Autoimmune, Experimental ; Humans ; Inflammation ; Microglia/immunology ; Microglia/metabolism ; Microglia/pathology ; Multiple Sclerosis/diagnosis
Czasopismo naukowe
Tytuł :
In Vitro Model to Investigate Communication between Dorsal Root Ganglion and Spinal Cord Glia.
Autorzy :
Ma J; AO Research Institute Davos, 7270 Davos, Switzerland.
Patil V; CÚRAM SFI Research Centre for Medical Devices, National University of Ireland Galway, H91 W2TY Galway, Ireland.
Pandit A; CÚRAM SFI Research Centre for Medical Devices, National University of Ireland Galway, H91 W2TY Galway, Ireland.
Quinlan LR; CÚRAM SFI Research Centre for Medical Devices, National University of Ireland Galway, H91 W2TY Galway, Ireland.
Finn DP; CÚRAM SFI Research Centre for Medical Devices, National University of Ireland Galway, H91 W2TY Galway, Ireland.
Grad S; AO Research Institute Davos, 7270 Davos, Switzerland.
Alini M; AO Research Institute Davos, 7270 Davos, Switzerland.
Peroglio M; AO Research Institute Davos, 7270 Davos, Switzerland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 08; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Communication*
Synaptic Transmission*
Ganglia, Spinal/*physiology
Neuroglia/*physiology
Spinal Cord/*physiology
Animals ; Animals, Newborn ; Biomarkers ; Calcium/metabolism ; Cells, Cultured ; Cytokines/metabolism ; Disease Susceptibility ; Fluorescent Antibody Technique ; Inflammation Mediators/metabolism ; Microglia/metabolism ; Models, Biological ; Neurons/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Cholinergic transmission in C. elegans: Functions, diversity, and maturation of ACh-activated ion channels.
Autorzy :
Treinin M; Department of Medical Neurobiology, Hadassah Medical school - Hebrew University, Jerusalem, Israel.
Jin Y; Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 Sep; Vol. 158 (6), pp. 1274-1291. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholine/*metabolism
Caenorhabditis elegans Proteins/*metabolism
Ion Channel Gating/*physiology
Locomotion/*physiology
Receptors, Cholinergic/*metabolism
Synaptic Transmission/*physiology
Acetylcholine/genetics ; Acetylcholine/pharmacology ; Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/physiology ; Cholinergic Agents/metabolism ; Cholinergic Agents/pharmacology ; Humans ; Ion Channel Gating/drug effects ; Muscle Contraction/drug effects ; Muscle Contraction/physiology ; Receptors, Cholinergic/genetics ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Kainate receptor modulation of glutamatergic synaptic transmission in the CA2 region of the hippocampus.
Autorzy :
Falcón-Moya R; Laboratorio de Neurociencia Celular y Plasticidad, Departamento de Fisiología, Anatomía y Biología Celular, Universidad Pablo de Olavide, Sevilla, Spain.
Martínez-Gallego I; Laboratorio de Neurociencia Celular y Plasticidad, Departamento de Fisiología, Anatomía y Biología Celular, Universidad Pablo de Olavide, Sevilla, Spain.
Rodríguez-Moreno A; Laboratorio de Neurociencia Celular y Plasticidad, Departamento de Fisiología, Anatomía y Biología Celular, Universidad Pablo de Olavide, Sevilla, Spain.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 Sep; Vol. 158 (5), pp. 1083-1093. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA2 Region, Hippocampal/*metabolism
Glutamic Acid/*metabolism
Receptors, Kainic Acid/*agonists
Receptors, Kainic Acid/*metabolism
Synaptic Transmission/*physiology
Animals ; CA2 Region, Hippocampal/drug effects ; Excitatory Amino Acid Agonists/pharmacology ; Female ; Kainic Acid/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Organ Culture Techniques ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Neurotransmitters responsible for purinergic motor neurotransmission and regulation of GI motility.
Autorzy :
Sanders KM; Department of Physiology and Cell Biology, University of Nevada, School of Medicine, 1664 North Virginia Street, Reno, NV 89557, USA. Electronic address: .
Mutafova-Yambolieva VN; Department of Physiology and Cell Biology, University of Nevada, School of Medicine, 1664 North Virginia Street, Reno, NV 89557, USA.
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Źródło :
Autonomic neuroscience : basic & clinical [Auton Neurosci] 2021 Sep; Vol. 234, pp. 102829. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Muscle, Smooth*
Synaptic Transmission*
Adenosine Triphosphate ; Animals ; Gastrointestinal Tract ; Mice ; Myocytes, Smooth Muscle ; Neurotransmitter Agents
Czasopismo naukowe
Tytuł :
Understanding neural signals of post-decisional performance monitoring: An integrative review.
Autorzy :
Desender K; Brain and Cognition, KU Leuven, Leuven, Belgium.; Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ridderinkhof KR; Department of Psychology, University of Amsterdam, Amsterdam, Netherlands.; Amsterdam center for Brain and Cognition (ABC), University of Amsterdam, Amsterdam, Netherlands.
Murphy PR; Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
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Źródło :
ELife [Elife] 2021 Aug 20; Vol. 10. Date of Electronic Publication: 2021 Aug 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Synaptic Transmission*
Cognition/*physiology
Decision Making/*physiology
Humans
Czasopismo naukowe
Tytuł :
Dual mechanisms of opioid-induced respiratory depression in the inspiratory rhythm-generating network.
Autorzy :
Baertsch NA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.; Department of Pediatrics, University of Washington, Seattle, United States.
Bush NE; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.
Burgraff NJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.
Ramirez JM; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.; Department of Pediatrics, University of Washington, Seattle, United States.; Department Neurological Surgery, University of Washington, Seattle, United States.
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Źródło :
ELife [Elife] 2021 Aug 17; Vol. 10. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Analgesics, Opioid/*adverse effects
Receptors, Opioid, mu/*genetics
Respiratory Center/*drug effects
Respiratory Insufficiency/*physiopathology
Synaptic Transmission/*drug effects
Animals ; Female ; Male ; Mice ; Mice, Transgenic ; Receptors, Opioid, mu/metabolism ; Respiratory Insufficiency/chemically induced ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł :
Sex Differences in the Hypothalamic Oxytocin Pathway to Locus Coeruleus and Augmented Attention with Chemogenetic Activation of Hypothalamic Oxytocin Neurons.
Autorzy :
Wang X; Department of Pharmacology and Physiology, School of Medicine and Health Sciences, The George University Washington, Washington, DC 20037, USA.
Escobar JB; Department of Pharmacology and Physiology, School of Medicine and Health Sciences, The George University Washington, Washington, DC 20037, USA.
Mendelowitz D; Department of Pharmacology and Physiology, School of Medicine and Health Sciences, The George University Washington, Washington, DC 20037, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 07; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Attention*
Sex Characteristics*
Synaptic Transmission*
Locus Coeruleus/*metabolism
Neurons/*metabolism
Oxytocin/*metabolism
Paraventricular Hypothalamic Nucleus/*metabolism
Animals ; CHO Cells ; Cricetulus ; Female ; Humans ; Male ; Oxytocin/genetics ; Rats ; Receptors, Oxytocin/genetics ; Receptors, Oxytocin/metabolism
Czasopismo naukowe
Tytuł :
Elimination of glutamatergic transmission from Hb9 interneurons does not impact treadmill locomotion.
Autorzy :
Koronfel LM; Department of Medical Neuroscience, Faculty of Medicine, Dalhousie University, Halifax, NS, B3H 4R2, Canada.; Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa, 904-0495, Japan.
Kanning KC; Center for Motor Neuron Biology and Disease, Columbia Stem Cell Initiative, Columbia Translational Neuroscience Initiative, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Neurology, and Neuroscience, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.; Regeneron Pharmaceuticals, 777 Old Saw Mill River Rd, Tarrytown, NY, 10591, USA.
Alcos A; Department of Medical Neuroscience, Faculty of Medicine, Dalhousie University, Halifax, NS, B3H 4R2, Canada.
Henderson CE; Center for Motor Neuron Biology and Disease, Columbia Stem Cell Initiative, Columbia Translational Neuroscience Initiative, Columbia University, New York, NY, 10032, USA.; Department of Pathology and Cell Biology, Neurology, and Neuroscience, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.; Biogen, Inc., 225 Binney St, Cambridge, MA, USA.
Brownstone RM; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, WC1N 3BG, UK. .
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Źródło :
Scientific reports [Sci Rep] 2021 Aug 06; Vol. 11 (1), pp. 16008. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Locomotion*
Physical Conditioning, Animal*
Synaptic Transmission*
Glutamates/*metabolism
Homeodomain Proteins/*physiology
Interneurons/*physiology
Synapses/*physiology
Transcription Factors/*physiology
Animals ; Female ; Gait ; Male ; Mice ; Mice, Transgenic ; Vesicular Glutamate Transport Protein 2/genetics ; Vesicular Glutamate Transport Protein 2/metabolism
Czasopismo naukowe
Tytuł :
Neuronal activity-induced SUMOylation of Akt1 by PIAS3 is required for long-term potentiation of synaptic transmission.
Autorzy :
Meng L; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Du CP; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Lu CY; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Zhang K; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Li L; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Yan JZ; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Hou XY; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.; State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Aug; Vol. 35 (8), pp. e21769.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hippocampus*/cytology
Hippocampus*/metabolism
Neurons*/cytology
Neurons*/metabolism
Synaptic Transmission*
Molecular Chaperones/*metabolism
Protein Inhibitors of Activated STAT/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Cells, Cultured ; Female ; HEK293 Cells ; Humans ; Male ; Phosphorylation ; Primary Cell Culture ; Rats ; Rats, Sprague-Dawley ; Sumoylation
Czasopismo naukowe
Tytuł :
The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling.
Autorzy :
Annamneedi A; Institute of Biology, Otto-Von-Guericke University, 39120 Magdeburg, Germany.; Center for Behavioral Brain Sciences (CBBS), 39120 Magdeburg, Germany.; Leibniz Institute for Neurobiology (LIN), RG Neuroplasticity, 39118 Magdeburg, Germany.
Del Angel M; Institute of Biology, Otto-Von-Guericke University, 39120 Magdeburg, Germany.
Gundelfinger ED; Center for Behavioral Brain Sciences (CBBS), 39120 Magdeburg, Germany.; Leibniz Institute for Neurobiology (LIN), RG Neuroplasticity, 39118 Magdeburg, Germany.; Institute of Pharmacology & Toxicology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Stork O; Institute of Biology, Otto-Von-Guericke University, 39120 Magdeburg, Germany.; Center for Behavioral Brain Sciences (CBBS), 39120 Magdeburg, Germany.
Çalışkan G; Institute of Biology, Otto-Von-Guericke University, 39120 Magdeburg, Germany.; Center for Behavioral Brain Sciences (CBBS), 39120 Magdeburg, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 26; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Synaptic Transmission*
Hippocampus/*metabolism
Membrane Glycoproteins/*metabolism
Nerve Tissue Proteins/*metabolism
Prosencephalon/*metabolism
Protein-Tyrosine Kinases/*metabolism
Animals ; Membrane Glycoproteins/genetics ; Mice ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Protein-Tyrosine Kinases/genetics
Czasopismo naukowe

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