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Wyszukujesz frazę ""Synaptic depression"" wg kryterium: Temat

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Wyświetlanie 1-20 z 2293
Tytuł:
Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition.
Autorzy:
Alegre-Zurano L; Neurobiology of Behaviour Research Group (GReNeC-NeuroBio), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, C/ Dr Aiguader, 88, 08003, Barcelona, Spain.
Caceres-Rodriguez A; INMED, INSERM U1249, Marseille, France.; Aix-Marseille University, Marseille, France.
Berbegal-Sáez P; Neurobiology of Behaviour Research Group (GReNeC-NeuroBio), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, C/ Dr Aiguader, 88, 08003, Barcelona, Spain.
Lassalle O; INMED, INSERM U1249, Marseille, France.; Aix-Marseille University, Marseille, France.
Manzoni O; INMED, INSERM U1249, Marseille, France.; Aix-Marseille University, Marseille, France.
Valverde O; Neurobiology of Behaviour Research Group (GReNeC-NeuroBio), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, C/ Dr Aiguader, 88, 08003, Barcelona, Spain. .; Neuroscience Research Program, IMIM-Hospital Del Mar Research Institute, Barcelona, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 25; Vol. 13 (1), pp. 18229. Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cocaine*/pharmacology
Long-Term Synaptic Depression*/drug effects
Animals ; Mice ; Amidohydrolases/genetics ; Endocannabinoids ; Saccharin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Updates on the Physiopathology of Group I Metabotropic Glutamate Receptors (mGluRI)-Dependent Long-Term Depression.
Autorzy:
Mango D; School of Pharmacy, University of Rome 'Tor Vergata', 00133 Rome, Italy.; Laboratory of Pharmacology of Synaptic Plasticity, European Brain Research Institute, 00161 Rome, Italy.
Ledonne A; Department of Systems Medicine, University of Rome 'Tor Vergata', 00133 Rome, Italy.; Department of Experimental Neuroscience, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy.
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Źródło:
Cells [Cells] 2023 Jun 08; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Long-Term Synaptic Depression*/physiology
Depression*
Neuronal Plasticity/physiology ; Neurons/physiology ; Synaptic Transmission
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses.
Autorzy:
Inglebert Y; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada. .; Current address Department of Neurosciences, Montreal University, Montreal, Canada. .
Wu PY; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
Tourbina-Kolomiets J; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
Dang CL; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
McKinney RA; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada. .
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Źródło:
Molecular brain [Mol Brain] 2024 Apr 02; Vol. 17 (1), pp. 17. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Depression*
Schaffer Collaterals*
Animals ; Mice ; Hippocampus/metabolism ; Long-Term Potentiation/physiology ; Long-Term Synaptic Depression/physiology ; Neuronal Plasticity/physiology ; Synapses/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Long-term depression in neurons involves temporal and ultra-structural dynamics of phosphatidylinositol-4,5-bisphosphate relying on PIP5K, PTEN and PLC.
Autorzy:
Hofbrucker-MacKenzie SA; Institute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany.
Seemann E; Institute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany.
Westermann M; Center for Electron Microscopy, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany.
Qualmann B; Institute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany. .
Kessels MM; Institute of Biochemistry I, Jena University Hospital - Friedrich Schiller University Jena, 07743, Jena, Germany. .
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Źródło:
Communications biology [Commun Biol] 2023 Apr 03; Vol. 6 (1), pp. 366. Date of Electronic Publication: 2023 Apr 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neurons*/physiology
Phosphatidylinositols*
Long-Term Synaptic Depression*
Neuronal Plasticity ; Phosphatidylinositol 4,5-Diphosphate/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GABA B R Modulation of Electrical Synapses and Plasticity in the Thalamic Reticular Nucleus.
Autorzy:
Wang H; Department of Biological Sciences, Lehigh University, 111 Research Drive, Bethlehem, PA 18015, USA.
Haas JS; Department of Biological Sciences, Lehigh University, 111 Research Drive, Bethlehem, PA 18015, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 09; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Electrical Synapses/*physiology
Long-Term Synaptic Depression/*genetics
Neuronal Plasticity/*genetics
Receptors, GABA-B/*genetics
Animals ; Humans ; Long-Term Synaptic Depression/physiology ; Neurons/metabolism ; Neurons/physiology ; Rats ; Thalamus/metabolism ; Thalamus/physiopathology ; Ventral Thalamic Nuclei/metabolism ; Ventral Thalamic Nuclei/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down's syndrome mouse model.
Autorzy:
Urbano-Gámez JD; Departamento de Fisiología Médica Y Biofísica, Universidad de Sevilla, Av. Sánchez-Pizjuán 4, 41009, Sevilla, Spain.; Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.
Casañas JJ; Departamento de Fisiología Médica Y Biofísica, Universidad de Sevilla, Av. Sánchez-Pizjuán 4, 41009, Sevilla, Spain.; Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.
Benito I; Departamento de Fisiología Médica Y Biofísica, Universidad de Sevilla, Av. Sánchez-Pizjuán 4, 41009, Sevilla, Spain.; Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.; Servicio de Animalario, Hospital Universitario Virgen Macarena (HUVM), 41009, Sevilla, Spain.
Montesinos ML; Departamento de Fisiología Médica Y Biofísica, Universidad de Sevilla, Av. Sánchez-Pizjuán 4, 41009, Sevilla, Spain. .; Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain. .
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Źródło:
Molecular brain [Mol Brain] 2021 May 25; Vol. 14 (1), pp. 84. Date of Electronic Publication: 2021 May 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Long-Term Synaptic Depression*/drug effects
Dendritic Spines/*metabolism
Dendritic Spines/*pathology
Down Syndrome/*pathology
Down Syndrome/*physiopathology
Receptors, Metabotropic Glutamate/*metabolism
Sirolimus/*pharmacology
Animals ; Dendritic Spines/drug effects ; Disease Models, Animal ; Fragile X Mental Retardation Protein/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Hippocampus/physiopathology ; Mice, Transgenic ; Mitochondrial Proteins/metabolism ; Neuronal Plasticity/drug effects ; Proteomics ; Pyramidal Cells/drug effects ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Synapses/drug effects ; Synapses/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
NMDA Receptor-Dependent Synaptic Depression in Potentiated Synapses of the Anterior Cingulate Cortex of adult Mice.
Autorzy:
Xue M; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, China.
Zhou SB; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, China.
Liu RH; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, China.
Chen QY; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, China.
Zhuo M; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, China.; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Li XH; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, China.; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
Molecular pain [Mol Pain] 2021 Jan-Dec; Vol. 17, pp. 17448069211018045.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Long-Term Synaptic Depression*
Receptors, N-Methyl-D-Aspartate*/metabolism
Animals ; Depression ; Electric Stimulation ; Gyrus Cinguli/metabolism ; Long-Term Potentiation ; Mice ; Synapses/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Input-selective adenosine A 1 receptor-mediated synaptic depression of excitatory transmission in dorsal striatum.
Autorzy:
Fritz BM; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Yin F; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Atwood BK; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. .; Department of Pharmacology and Toxicology, Indiana University School of Medicine, 320 W. 15th Street, NB-400C, Indianapolis, IN, 46202, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 18; Vol. 11 (1), pp. 6345. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Compulsive Behavior/*genetics
Corpus Striatum/*physiology
Long-Term Synaptic Depression/*genetics
Receptor, Adenosine A1/*genetics
Adenosine/pharmacology ; Animals ; Behavior, Animal/physiology ; Excitatory Postsynaptic Potentials ; Female ; Long-Term Synaptic Depression/physiology ; Male ; Mice ; Mice, Knockout ; Neurons/pathology ; Neurons/physiology ; Patch-Clamp Techniques ; Synapses/physiology ; Synaptic Transmission ; Thalamus/drug effects ; Thalamus/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Loss of retinoid X receptor gamma subunit impairs group 1 mGluR mediated electrophysiological responses and group 1 mGluR dependent behaviors.
Autorzy:
Upreti C; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, 10595, USA.
Woodruff CM; Department of Neuroscience, Columbia University, 3227 Broadway, New York, NY, 10027, USA.
Zhang XL; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, 10595, USA.
Yim MJ; Department of Neuroscience, Columbia University, 3227 Broadway, New York, NY, 10027, USA.
Zhou ZY; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, 10595, USA.; Department of Neurology, New York Medical College, Valhalla, NY, 10595, USA.
Pagano AM; Department of Neuroscience, Columbia University, 3227 Broadway, New York, NY, 10027, USA.
Rehanian DS; Department of Pathology and Cell Biology, Columbia University, 630 West 168thStreet, New York, NY, 10032, USA.; Taub Institute for Research on Alzheimer's Disease and Aging Brain, Columbia University, 630 West 168thStreet, New York, NY, 10032, USA.
Yin D; Department of Neuroscience, Columbia University, 3227 Broadway, New York, NY, 10027, USA.; Howard Hughes Medical Institute, Columbia University, 3227 Broadway, New York, NY, 10027, USA.
Kandel ER; Department of Neuroscience, Columbia University, 3227 Broadway, New York, NY, 10027, USA.; Howard Hughes Medical Institute, Columbia University, 3227 Broadway, New York, NY, 10027, USA.; Kavli Institute for Brain Science, Columbia University, 3227 Broadway, New York, NY, 10027, USA.; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, 3227 Broadway, New York, NY, 10027, USA.
Stanton PK; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, 10595, USA.; Department of Neurology, New York Medical College, Valhalla, NY, 10595, USA.
Nicholls RE; Department of Pathology and Cell Biology, Columbia University, 630 West 168thStreet, New York, NY, 10032, USA. .; Taub Institute for Research on Alzheimer's Disease and Aging Brain, Columbia University, 630 West 168thStreet, New York, NY, 10032, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Mar 10; Vol. 11 (1), pp. 5552. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Long-Term Synaptic Depression*
Signal Transduction*
CA1 Region, Hippocampal/*metabolism
Pyramidal Cells/*metabolism
Receptors, Metabotropic Glutamate/*metabolism
Retinoid X Receptor gamma/*metabolism
Synapses/*metabolism
Animals ; Mice ; Mice, Knockout ; Receptors, Metabotropic Glutamate/genetics ; Retinoid X Receptor gamma/genetics ; Synapses/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The loss of NMDAR-dependent LTD following cannabinoid self-administration is restored by positive allosteric modulation of CB1 receptors.
Autorzy:
Neuhofer D; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina.
Spencer SM; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina.; Department of Pharmacology, Medical Discovery Team on Addiction, University of Minnesota, Minneapolis, Minnesota.
Chioma VC; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina.
Beloate LN; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina.
Schwartz D; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina.
Kalivas PW; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina.
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Źródło:
Addiction biology [Addict Biol] 2020 Nov; Vol. 25 (6), pp. e12843. Date of Electronic Publication: 2019 Nov 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cannabidiol/*pharmacology
Cannabinoids/*pharmacology
Dronabinol/*pharmacology
Long-Term Synaptic Depression/*drug effects
Receptor, Cannabinoid, CB1/*agonists
Receptors, N-Methyl-D-Aspartate/*physiology
Allosteric Regulation/drug effects ; Animals ; Behavior, Addictive/chemically induced ; Cannabidiol/administration & dosage ; Cannabinoid Receptor Agonists/administration & dosage ; Cannabinoid Receptor Agonists/pharmacology ; Cannabinoids/administration & dosage ; Dronabinol/administration & dosage ; Glutamic Acid/metabolism ; Indoles/administration & dosage ; Indoles/pharmacology ; Long-Term Synaptic Depression/physiology ; Male ; Nucleus Accumbens/drug effects ; Rats ; Rats, Sprague-Dawley ; Self Administration ; Synaptic Transmission/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 2293

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