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Wyświetlanie 1-20 z 28307
Tytuł:
Control Theory and Systems Biology: Potential Applications in Neurodegeneration and Search for Therapeutic Targets.
Autorzy:
Angarita-Rodríguez A; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Edf. Carlos Ortiz, Oficina 107, Cra. 7 40-62, Bogotá 110231, Colombia.; Laboratorio de Bioinformática y Biología de Sistemas, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
González-Giraldo Y; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Edf. Carlos Ortiz, Oficina 107, Cra. 7 40-62, Bogotá 110231, Colombia.
Rubio-Mesa JJ; Departamento de Estadística, Facultad de Ciencias, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
Aristizábal AF; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Edf. Carlos Ortiz, Oficina 107, Cra. 7 40-62, Bogotá 110231, Colombia.
Pinzón A; Laboratorio de Bioinformática y Biología de Sistemas, Universidad Nacional de Colombia, Bogotá 111321, Colombia.
González J; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Edf. Carlos Ortiz, Oficina 107, Cra. 7 40-62, Bogotá 110231, Colombia.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 27; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Systems Biology*
Drug Development*
Genomics ; Interdisciplinary Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrated systems biology approach identifies gene targets for endothelial dysfunction.
Autorzy:
Pinheiro-de-Sousa I; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Fonseca-Alaniz MH; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.
Giudice G; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Valadão IC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.
Modestia SM; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.
Mattioli SV; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.; Department of Biophysics and Pharmacology, Institute of Biosciences of Botucatu, Universidade Estadual Paulista, Botucatu, Brazil.
Junior RR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.
Zalmas LP; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.; Open Targets, Wellcome Genome Campus, Cambridge, UK.
Fang Y; Department of Medicine, University of Chicago, Chicago, IL, USA.
Petsalaki E; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor)/University of São Paulo Medical School, São Paulo, Brazil.
Źródło:
Molecular systems biology [Mol Syst Biol] 2023 Dec 06; Vol. 19 (12), pp. e11462. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Systems Biology*
RNA, Small Interfering
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An architecture for collaboration in systems biology at the age of the Metaverse.
Autorzy:
Jacopin E; RIKEN, Center for Biosystems Dynamics Research, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan. .
Sakamoto Y; RIKEN, Center for Biosystems Dynamics Research, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan.
Nishida K; RIKEN, Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.; Tokyo University of Agriculture and Technology, Department of Biotechnology and Life Science, 2-24-16 Nakamachi, Koganei, Tokyo, 184-8588, Japan.
Kaizu K; RIKEN, Center for Biosystems Dynamics Research, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan.
Takahashi K; RIKEN, Center for Biosystems Dynamics Research, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan.
Źródło:
NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Jan 27; Vol. 10 (1), pp. 12. Date of Electronic Publication: 2024 Jan 27.
Typ publikacji:
Journal Article
MeSH Terms:
Systems Biology*
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PyRates-A code-generation tool for modeling dynamical systems in biology and beyond.
Autorzy:
Gast R; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.
Knösche TR; Brain Networks Group, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Kennedy A; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, United States of America.
Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Dec 27; Vol. 19 (12), pp. e1011761. Date of Electronic Publication: 2023 Dec 27 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Ecosystem*
Systems Biology*/methods
Software ; Computer Simulation ; Brain ; Models, Biological
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ICON-GEMs: integration of co-expression network in genome-scale metabolic models, shedding light through systems biology.
Autorzy:
Paklao T; Advanced Virtual and Intelligent Computing (AVIC) Center, Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Suratanee A; Department of Mathematics, Faculty of Applied Science, King Mongkut's University of Technology North Bangkok, Bangkok, 10800, Thailand.
Plaimas K; Advanced Virtual and Intelligent Computing (AVIC) Center, Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. .; Omics Sciences and Bioinformatics Center, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. .
Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 Dec 21; Vol. 24 (1), pp. 492. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Proteomics*
Systems Biology*
Genome ; Metabolic Engineering ; Gene Expression Profiling ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Models, Biological ; Metabolic Networks and Pathways/genetics ; Metabolic Flux Analysis/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SBMLKinetics: a tool for annotation-independent classification of reaction kinetics for SBML models.
Autorzy:
Xu J; Department of Bioengineering, University of Washington, Seattle, USA. .
Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 Jun 13; Vol. 24 (1), pp. 248. Date of Electronic Publication: 2023 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*
Systems Biology*
Kinetics ; Probability
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Drug Target Identification and Drug Repurposing in Psoriasis through Systems Biology Approach, DNN-Based DTI Model and Genome-Wide Microarray Data.
Autorzy:
Zhan YP; Laboratory of Automatic Control, Signal Processing and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
Chen BS; Laboratory of Automatic Control, Signal Processing and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 12; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 12.
Typ publikacji:
Journal Article
MeSH Terms:
Systems Biology*
Psoriasis*/drug therapy
Psoriasis*/genetics
Humans ; Drug Repositioning ; Microarray Analysis ; Neural Networks, Computer
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Adapting modeling and simulation credibility standards to computational systems biology.
Autorzy:
Tatka LT; Department of Bioengineering, University of Washington, Seattle, WA, USA. .
Smith LP; Department of Bioengineering, University of Washington, Seattle, WA, USA.
Hellerstein JL; eScience Institute, University of Washington, Seattle, WA, USA.
Sauro HM; Department of Bioengineering, University of Washington, Seattle, WA, USA.
Źródło:
Journal of translational medicine [J Transl Med] 2023 Jul 26; Vol. 21 (1), pp. 501. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Systems Biology*
Computational Biology*
Computer Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Systems biology approaches to identify potential targets and inhibitors of the intestinal microbiota to treat depression.
Autorzy:
Teng F; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Lu Z; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Gao F; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Liang J; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Li J; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Tian X; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Wang X; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Guan H; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China.
Wang J; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250014, China. .
Źródło:
Scientific reports [Sci Rep] 2023 Jul 11; Vol. 13 (1), pp. 11225. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Systems Biology*
Gastrointestinal Microbiome*
Humans ; Depression/drug therapy ; Equol ; Genistein/pharmacology ; Genistein/therapeutic use ; Molecular Docking Simulation ; Quercetin/pharmacology ; Quercetin/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Systems Biology and Omics Approaches for Complex Human Diseases.
Autorzy:
Selvarajoo K; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore 138671, Singapore.; Synthetic Biology for Clinical and Technological Innovation (SynCTI), National University of Singapore (NUS), Singapore 117456, Singapore.; School of Biological Sciences, Nanyang Technological University (NTU), Singapore 639798, Singapore.
Giuliani A; Environment and Health Department, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Źródło:
Biomolecules [Biomolecules] 2023 Jul 06; Vol. 13 (7). Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Editorial
MeSH Terms:
Systems Biology*
Humans
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway.
Autorzy:
Knöchel J; Institute of Mathematics, Universität Potsdam, Potsdam, Germany.; Graduate Research Training Program PharMetrX: Pharmacometrics & Computational Disease Modeling, Freie Universität Berlin and Universität Potsdam, Berlin/Potsdam, Germany.
Kloft C; Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universität Berlin, Berlin, Germany.
Huisinga W; Institute of Mathematics, Universität Potsdam, Potsdam, Germany.
Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 Feb 05; Vol. 20 (2), pp. e1011777. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Signal Transduction*/physiology
Computer Simulation ; Systems Biology/methods ; ErbB Receptors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Forward Genetics-Based Approaches to Understanding the Systems Biology and Molecular Mechanisms of Epilepsy.
Autorzy:
Shevlyakov AD; Graduate Program in Bioinformatics and Genomics, Sirius University of Science and Technology, 354340 Sochi, Russia.; Neuroscience Program, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kolesnikova TO; Neuroscience Program, Sirius University of Science and Technology, 354340 Sochi, Russia.
de Abreu MS; Moscow Institute of Physics and Technology, 11730 Moscow, Russia.
Petersen EV; Moscow Institute of Physics and Technology, 11730 Moscow, Russia.
Yenkoyan KB; Neuroscience Laboratory of COBRAIN Center for Fundamental Brain Research, and Biochemistry Department, Yerevan State Medical University named after M. Heratsi, Yerevan 0025, Armenia.
Demin KA; Institute of Translational Biomedicine, St. Petersburg State University, 199034 St. Petersburg, Russia.; Institute of Experimental Medicine, Almazov National Medical Research Centre, Ministry of Healthcare of Russian Federation, 194021 St. Petersburg, Russia.
Kalueff AV; Neuroscience Program, Sirius University of Science and Technology, 354340 Sochi, Russia.; Neuroscience Laboratory of COBRAIN Center for Fundamental Brain Research, and Biochemistry Department, Yerevan State Medical University named after M. Heratsi, Yerevan 0025, Armenia.; Institute of Translational Biomedicine, St. Petersburg State University, 199034 St. Petersburg, Russia.; Institute of Experimental Medicine, Almazov National Medical Research Centre, Ministry of Healthcare of Russian Federation, 194021 St. Petersburg, Russia.; Laboratory of Preclinical Bioscreening, Granov Russian Research Center of Radiology and Surgical Technologies, Ministry of Healthcare of Russian Federation, 197758 Pesochny, Russia.; Neuroscience Group, Ural Federal University, 620002 Ekaterinburg, Russia.; Laboratory of Biopsychiatry, Scientific Research Institute of Physiology and Basic Medicine, 630117 Novosibirsk, Russia.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 09; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Systems Biology*
Epilepsy*/drug therapy
Humans ; Seizures/drug therapy ; Anticonvulsants/therapeutic use ; Genome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
FBA-PRCC. Partial Rank Correlation Coefficient (PRCC) Global Sensitivity Analysis (GSA) in Application to Constraint-Based Models.
Autorzy:
Sorokin A; Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.
Goryanin I; Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.; School of Informatics, The University of Edinburgh, Informatics Forum, Edinburgh EH8 9AB, UK.
Źródło:
Biomolecules [Biomolecules] 2023 Mar 09; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Systems Biology*
Genome*
Metabolic Networks and Pathways ; Biotechnology ; Models, Biological
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bayesian estimation reveals that reproducible models in Systems Biology get more citations.
Autorzy:
Höpfl S; Institute for Systems Theory and Automatic Control, University of Stuttgart, Pfaffenwaldring 9, 70569, Stuttgart, Germany.
Pleiss J; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569, Stuttgart, Germany.
Radde NE; Institute for Systems Theory and Automatic Control, University of Stuttgart, Pfaffenwaldring 9, 70569, Stuttgart, Germany. .
Źródło:
Scientific reports [Sci Rep] 2023 Feb 15; Vol. 13 (1), pp. 2695. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Systems Biology*
Journal Impact Factor*
Bayes Theorem ; Reproducibility of Results ; Publications
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The New Year of Systems Biology in Reproductive Medicine.
Autorzy:
Krawetz SA; SBiRM: Systems Biology in Reproductive Medicine; Charlotte B. Failing Professor of Fetal Therapy and Diagnosis, Department of Obstetrics and Gynecology, Center for Molecular Medicine & Genetics, and C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, USA.
Źródło:
Systems biology in reproductive medicine [Syst Biol Reprod Med] 2023 Feb; Vol. 69 (1), pp. 1-2. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Editorial
MeSH Terms:
Systems Biology*
Reproductive Medicine*
Reproduction
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Machine learning alternative to systems biology should not solely depend on data.
Autorzy:
Yeo HC; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore.
Selvarajoo K; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore.; Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Synthetic Biology for Clinical and Technological Innovation (SynCTI), National University of Singapore (NUS), Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University (NTU), Singapore.
Źródło:
Briefings in bioinformatics [Brief Bioinform] 2022 Nov 19; Vol. 23 (6).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Systems Biology*
Artificial Intelligence*
Machine Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficient computation of adjoint sensitivities at steady-state in ODE models of biochemical reaction networks.
Autorzy:
Lakrisenko P; Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.; Center for Mathematics, Technische Universität München, Garching, Germany.
Stapor P; Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.; Center for Mathematics, Technische Universität München, Garching, Germany.
Grein S; University of Bonn, Life and Medical Sciences Institute, Bonn, Germany.
Paszkowski Ł; Simula Research Laboratory, Oslo, Norway.
Pathirana D; University of Bonn, Life and Medical Sciences Institute, Bonn, Germany.
Fröhlich F; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America.
Lines GT; Simula Research Laboratory, Oslo, Norway.
Weindl D; Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Hasenauer J; Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.; University of Bonn, Life and Medical Sciences Institute, Bonn, Germany.
Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Jan 03; Vol. 19 (1), pp. e1010783. Date of Electronic Publication: 2023 Jan 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Models, Biological*
Systems Biology*/methods
Computer Simulation ; Algorithms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 28307

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