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Wyszukujesz frazę ""T cell receptor"" wg kryterium: Wszystkie pola


Tytuł :
Characterization and Monitoring of Antigen-Responsive T Cell Clones Using T Cell Receptor Gene Expression Analysis.
Autorzy :
Pollastro S; Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology and Immunology Centre (ARC), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Experimental Immunology, Amsterdam Infection & Immunity Institute (AIII), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
de Bourayne M; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé, SIMoS, Gif-sur-Yvette, France.
Balzaretti G; Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology and Immunology Centre (ARC), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Experimental Immunology, Amsterdam Infection & Immunity Institute (AIII), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
Jongejan A; Department of Clinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam Infection & Immunity Institute (AIII), Amsterdam Public Health Research Institute, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
van Schaik BDC; Department of Clinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam Infection & Immunity Institute (AIII), Amsterdam Public Health Research Institute, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
Niewold ITG; Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology and Immunology Centre (ARC), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
van Kampen AHC; Department of Clinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam Infection & Immunity Institute (AIII), Amsterdam Public Health Research Institute, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
Maillère B; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé, SIMoS, Gif-sur-Yvette, France.
de Vries N; Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology and Immunology Centre (ARC), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Experimental Immunology, Amsterdam Infection & Immunity Institute (AIII), Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, Netherlands.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Feb 19; Vol. 11, pp. 609624. Date of Electronic Publication: 2021 Feb 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens/*immunology
Clone Cells/*immunology
Gene Expression/*immunology
Genes, T-Cell Receptor/*immunology
Receptors, Antigen, T-Cell/*immunology
T-Lymphocytes/*immunology
Antigens/genetics ; Gene Expression/genetics ; Genes, T-Cell Receptor/genetics ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Interleukin-4/genetics ; Interleukin-4/immunology ; Receptors, Antigen, T-Cell/genetics
Czasopismo naukowe
Tytuł :
Decombinator V4: an improved AIRR compliant-software package for T-cell receptor sequence annotation?
Autorzy :
Peacock T; Division of Infection and Immunity, UCL, WC1E 6BT, London, UK.; CoMPLEX, Department of Computer Science, UCL, WC1E 7JG, London, UK.
Heather JM; Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA 02115, USA.
Ronel T; Division of Infection and Immunity, UCL, WC1E 6BT, London, UK.; Cancer Institute, UCL, WC1E 6DD, London, UK.
Chain B; Division of Infection and Immunity, UCL, WC1E 6BT, London, UK.; CoMPLEX, Department of Computer Science, UCL, WC1E 7JG, London, UK.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 May 05; Vol. 37 (6), pp. 876-878.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Antigen, T-Cell*/genetics
Software*
Algorithms
Czasopismo naukowe
Tytuł :
Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases.
Autorzy :
Barennes P; Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.
Quiniou V; Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.
Shugay M; Center of Life Sciences, Skoltech, Moscow, Russia.; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia.
Egorov ES; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
Davydov AN; Adaptive Immunity Group, Central European Institute of Technology, Brno, Czechia.
Chudakov DM; Center of Life Sciences, Skoltech, Moscow, Russia.; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia.; Adaptive Immunity Group, Central European Institute of Technology, Brno, Czechia.
Uddin I; Division of Infection and Immunity, University College London, London, UK.
Ismail M; Division of Infection and Immunity, University College London, London, UK.
Oakes T; Division of Infection and Immunity, University College London, London, UK.
Chain B; Division of Infection and Immunity, University College London, London, UK.
Eugster A; DFG-Centre for Regenerative Therapies Dresden, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Kashofer K; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Rainer PP; Division of Cardiology, Medical University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.
Darko S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ransier A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Klatzmann D; Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.
Mariotti-Ferrandiz E; Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), Paris, France. .; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France. .
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Źródło :
Nature biotechnology [Nat Biotechnol] 2021 Feb; Vol. 39 (2), pp. 236-245. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
High-Throughput Nucleotide Sequencing/*methods
Receptors, Antigen, T-Cell/*genetics
Adult ; Bias ; Computer Simulation ; Humans ; Jurkat Cells ; Male ; Middle Aged ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Mapping the functional landscape of T cell receptor repertoires by single-T cell transcriptomics.
Autorzy :
Zhang Z; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Xiong D; Department of Statistical Science, Southern Methodist University, Dallas, TX, USA.
Wang X; Department of Statistical Science, Southern Methodist University, Dallas, TX, USA.
Liu H; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Wang T; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA. .; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA. .
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Źródło :
Nature methods [Nat Methods] 2021 Jan; Vol. 18 (1), pp. 92-99. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Transcriptome*
Lymphocytes, Tumor-Infiltrating/*immunology
Neoplasms/*immunology
Receptors, Antigen, T-Cell/*genetics
Receptors, Antigen, T-Cell/*immunology
Single-Cell Analysis/*methods
T-Lymphocytes/*immunology
Computational Biology/methods ; High-Throughput Nucleotide Sequencing ; Humans ; Neoplasms/genetics ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Ceramide Synthase 2 Null Mice Are Protected from Ovalbumin-Induced Asthma with Higher T Cell Receptor Signal Strength in CD4+ T Cells.
Autorzy :
Shin SH; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
Cho KA; Department of Microbiology, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
Yoon HS; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
Kim SY; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
Kim HY; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
Pewzner-Jung Y; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.
Jung SA; Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
Park WJ; Department of Biochemistry, College of Medicine, Gachon University, Incheon 21999, Korea.
Futerman AH; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.
Park JW; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul 07804, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 08; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma/*immunology
Receptors, Antigen, T-Cell/*immunology
Signal Transduction/*immunology
Sphingosine N-Acyltransferase/*deficiency
Th17 Cells/*immunology
Th2 Cells/*immunology
Animals ; Asthma/chemically induced ; Asthma/genetics ; Asthma/pathology ; Mice ; Mice, Knockout ; Ovalbumin/toxicity ; Receptors, Antigen, T-Cell/genetics ; Signal Transduction/genetics ; Sphingosine N-Acyltransferase/immunology ; Th17 Cells/pathology ; Th2 Cells/pathology
Czasopismo naukowe
Tytuł :
Affinity Maturation of a T-Cell Receptor-Like Antibody Specific for a Cytomegalovirus pp65-Derived Peptide Presented by HLA-A*02:01.
Autorzy :
Lee SY; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.
Ko DH; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.
Son MJ; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.
Kim JA; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.
Jung K; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon 16499, Korea.
Kim YS; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon 16499, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 26; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies/*immunology
Cytomegalovirus/*immunology
Cytomegalovirus Infections/*immunology
HLA-A Antigens/*immunology
Receptors, Antigen, T-Cell/*immunology
Viral Matrix Proteins/*immunology
Antibody Affinity ; Cell Line ; Humans ; Peptides/immunology
Czasopismo naukowe
Tytuł :
Low T-cell receptor excision circles (TREC) in children and adolescents with immune thrombocytopenia.
Autorzy :
Santana-Santos D; Laboratory of Medical Investigation (LIM36) of Department of Pediatrics, Universidade de São Paulo, São Paulo, Brazil.
Liphaus BL; Laboratory of Medical Investigation (LIM36) of Department of Pediatrics, Universidade de São Paulo, São Paulo, Brazil.
Beatrice JM; Pediatric Hematology Unit, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Carneiro JDA; Pediatric Hematology Unit, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Carneiro-Sampaio MMS; Laboratory of Medical Investigation (LIM36) of Department of Pediatrics, Universidade de São Paulo, São Paulo, Brazil.
Rangel-Santos A; Laboratory of Medical Investigation (LIM36) of Department of Pediatrics, Universidade de São Paulo, São Paulo, Brazil.
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Źródło :
British journal of haematology [Br J Haematol] 2021 Feb; Vol. 192 (4), pp. e99-e102. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA, Circular/*genetics
Purpura, Thrombocytopenic, Idiopathic/*genetics
Receptors, Antigen, T-Cell/*genetics
Adolescent ; Child ; Child, Preschool ; DNA, Circular/immunology ; Female ; Humans ; Male ; Purpura, Thrombocytopenic, Idiopathic/immunology ; Receptors, Antigen, T-Cell/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Thymus Gland/immunology ; Thymus Gland/metabolism
Raport
Tytuł :
T cell receptor repertoire as a potential diagnostic marker for celiac disease.
Autorzy :
Yao Y; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway.
Zia A; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway.
Neumann RS; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway.
Pavlovic M; Department of Informatics, University of Oslo, Norway.
Balaban G; Department of Informatics, University of Oslo, Norway.
Lundin KEA; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway.
Sandve GK; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway; Department of Informatics, University of Oslo, Norway.
Qiao SW; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway. Electronic address: .
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Źródło :
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2021 Jan; Vol. 222, pp. 108621. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Celiac Disease/*diagnosis
Celiac Disease/*immunology
Epitopes, T-Lymphocyte/*immunology
Receptors, Antigen, T-Cell/*immunology
Adolescent ; Adult ; Aged ; Biomarkers ; HLA-DQ Antigens/genetics ; HLA-DQ Antigens/immunology ; Humans ; Lymphocyte Activation/immunology ; Middle Aged ; Mucous Membrane/cytology ; Mucous Membrane/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Transplantation of T-cell receptor α/β-depleted allogeneic bone marrow in nonhuman primates.
Autorzy :
D'Souza SS; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI.
Bennett S; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI.
Kumar A; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI.
Kelnhofer LE; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI.
Weinfurter J; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI.
Suknuntha K; Department of Pathology and Laboratory Medicine, School of Medicine, University of Wisconsin-Madison, Madison, WI; Chakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.
Coonen J; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI.
Mejia A; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI.
Simmons H; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI.
Golos T; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI; Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Hematti P; Carbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI; Division of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI.
Capitini CM; Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Reynolds MR; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI.
Slukvin II; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI; Department of Pathology and Laboratory Medicine, School of Medicine, University of Wisconsin-Madison, Madison, WI; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Madison, WI. Electronic address: .
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Źródło :
Experimental hematology [Exp Hematol] 2021 Jan; Vol. 93, pp. 44-51. Date of Electronic Publication: 2020 Nov 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Marrow Cells/*cytology
Graft vs Host Disease/*prevention & control
Hematopoietic Stem Cell Transplantation/*methods
Receptors, Antigen, T-Cell/*isolation & purification
Animals ; Female ; Hematopoietic Stem Cells/cytology ; Immunosuppressive Agents/therapeutic use ; Macaca fascicularis ; Male ; Sirolimus/therapeutic use ; Transplantation Conditioning/methods ; Transplantation, Homologous/methods ; Whole-Body Irradiation/methods
Czasopismo naukowe
Tytuł :
Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences.
Autorzy :
Yohannes DA; Research Programs Unit, Translational Immunology, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.
Kaukinen K; Department of Internal Medicine, Faculty of Medicine and Health Technology, Tampere University Hospital, Tampere University, Tampere, Finland.
Kurppa K; Department of Pediatrics, Tampere University Hospital and Center for Child Health Research, Tampere University, Tampere, Finland.
Saavalainen P; Research Programs Unit, Translational Immunology, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.
Greco D; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. .; BioMediTech Institute, Tampere University, Tampere, Finland. .; Institute of Biotechnology, University of Helsinki, Helsinki, Finland. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Mar 25; Vol. 22 (1), pp. 159. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Antigen, T-Cell*
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Cluster Analysis ; Humans ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
Empirical and Rational Design of T Cell Receptor-Based Immunotherapies.
Autorzy :
Jones HF; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States.; Weill Cornell Medicine, New York, NY, United States.
Molvi Z; Weill Cornell Medicine, New York, NY, United States.; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Klatt MG; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Dao T; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Scheinberg DA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States.; Weill Cornell Medicine, New York, NY, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jan 25; Vol. 11, pp. 585385. Date of Electronic Publication: 2021 Jan 25 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunotherapy*
Receptors, Antigen, T-Cell/*immunology
Animals ; Humans
Czasopismo naukowe
Tytuł :
Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans.
Autorzy :
Gordin M; The Mina & Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat-Gan, Israel.
Philip H; The Mina & Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat-Gan, Israel.
Zilberberg A; The Mina & Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat-Gan, Israel.
Gidoni M; Faculty of Engineering, Bar Ilan University, Ramat Gan, Israel.
Margalit R; Science in Action Ltd., Ness Ziona, Israel.
Clouser C; Juno Therapeutics, Seattle, Washington, United States of America.
Adams K; Juno Therapeutics, Seattle, Washington, United States of America.
Vigneault F; Juno Therapeutics, Seattle, Washington, United States of America.
Cohen IR; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel.
Yaari G; Faculty of Engineering, Bar Ilan University, Ramat Gan, Israel.
Efroni S; The Mina & Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat-Gan, Israel.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 Jan 19; Vol. 17 (1), pp. e1008486. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*/genetics
Breast Neoplasms*/immunology
Breast Neoplasms*/metabolism
Receptors, Antigen, T-Cell*/chemistry
Receptors, Antigen, T-Cell*/genetics
Receptors, Antigen, T-Cell*/metabolism
Complementarity Determining Regions/*genetics
Animals ; Cells, Cultured ; Complementarity Determining Regions/chemistry ; Complementarity Determining Regions/metabolism ; Databases, Genetic ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Mice ; Mice, Transgenic ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
Intrinsic Disorder in the T Cell Receptor Creates Cooperativity and Controls ZAP70 Binding.
Autorzy :
Clemens L; Center for Complex Biological Systems, University of California Irvine, Irvine, California.
Dushek O; Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Allard J; Center for Complex Biological Systems, University of California Irvine, Irvine, California; Department of Mathematics and Department of Physics and Astronomy, University of California Irvine, Irvine, California. Electronic address: .
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Źródło :
Biophysical journal [Biophys J] 2021 Jan 19; Vol. 120 (2), pp. 379-392. Date of Electronic Publication: 2020 Dec 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Receptors, Antigen, T-Cell*/metabolism
Signal Transduction*
ZAP-70 Protein-Tyrosine Kinase*/metabolism
Cell Membrane/metabolism ; Intrinsically Disordered Proteins ; Kinetics ; Phosphorylation
Czasopismo naukowe
Tytuł :
TCRdb: a comprehensive database for T-cell receptor sequences with powerful search function.
Autorzy :
Chen SY; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology; Wuhan, 430074, China.
Yue T; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology; Wuhan, 430074, China.
Lei Q; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology; Wuhan, 430074, China.
Guo AY; Center for Artificial Intelligence Biology, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology; Wuhan, 430074, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 08; Vol. 49 (D1), pp. D468-D474.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Databases, Protein*
Search Engine*
Receptors, Antigen, T-Cell/*chemistry
Amino Acid Sequence ; Internet
Czasopismo naukowe
Tytuł :
Exploring the different states of wild-type T-cell receptor and mutant conformational changes towards understanding the antigen recognition.
Autorzy :
Tripathi SK; Structural Immunology Group, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India.
Salunke DM; Structural Immunology Group, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India.; Structural Immunology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Jan; Vol. 39 (1), pp. 188-201. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Complementarity Determining Regions*/metabolism
Receptors, Antigen, T-Cell*/genetics
Receptors, Antigen, T-Cell*/metabolism
Molecular Conformation ; Peptides/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
The molecular assembly of the marsupial γμ T cell receptor defines a third T cell lineage.
Autorzy :
Morrissey KA; Department of Biology, Center for Evolutionary and Theoretical Immunology, University of New Mexico, Albuquerque, NM, USA.
Wegrecki M; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Praveena T; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria, Australia.
Hansen VL; Department of Biology, Center for Evolutionary and Theoretical Immunology, University of New Mexico, Albuquerque, NM, USA.
Bu L; Department of Biology, Center for Evolutionary and Theoretical Immunology, University of New Mexico, Albuquerque, NM, USA.
Sivaraman KK; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Darko S; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Douek DC; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Rossjohn J; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. .; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria, Australia.; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK.
Miller RD; Department of Biology, Center for Evolutionary and Theoretical Immunology, University of New Mexico, Albuquerque, NM, USA. .
Le Nours J; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. .; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria, Australia.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Mar 26; Vol. 371 (6536), pp. 1383-1388.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Monodelphis/*immunology
Receptors, Antigen, T-Cell/*chemistry
T-Lymphocyte Subsets/*immunology
Animals ; Cell Lineage ; Complementarity Determining Regions/chemistry ; Crystallography, X-Ray ; Models, Molecular ; Monodelphis/genetics ; Protein Conformation ; Protein Domains ; Protein Multimerization ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell, alpha-beta ; Receptors, Antigen, T-Cell, gamma-delta
Czasopismo naukowe
Tytuł :
T cell receptor diversity, specificity and promiscuity of functionally heterogeneous human MR1-restricted T cells.
Autorzy :
Lepore M; Immunocore Ltd Milton Park, Abingdon, United Kingdom. Electronic address: .
Lewinsohn DA; Department of Pediatrics, Oregon Health & Science University, Portland, OR, United States.
Lewinsohn DM; Department of Medicine, Oregon Health & Science University, Portland VA Medical Center, Portland, OR, United States. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2021 Feb; Vol. 130, pp. 64-68. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Histocompatibility Antigens Class I/*metabolism
Minor Histocompatibility Antigens/*metabolism
Mucosal-Associated Invariant T Cells/*metabolism
Receptors, Antigen, T-Cell/*immunology
T-Cell Antigen Receptor Specificity/*physiology
T-Lymphocyte Subsets/*immunology
Histocompatibility Antigens Class I/immunology ; Humans ; Immunity, Mucosal/immunology ; Minor Histocompatibility Antigens/immunology ; Mucosal-Associated Invariant T Cells/immunology ; Receptors, Antigen, T-Cell/physiology ; Receptors, Antigen, T-Cell, alpha-beta
Czasopismo naukowe
Tytuł :
T cell receptor therapy against melanoma-Immunotherapy for the future?
Autorzy :
Winge-Main AK; Department of Cellular Therapy, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.; Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Wälchli S; Department of Cellular Therapy, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Inderberg EM; Department of Cellular Therapy, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
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Źródło :
Scandinavian journal of immunology [Scand J Immunol] 2020 Oct; Vol. 92 (4), pp. e12927.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunotherapy/*methods
Melanoma/*immunology
Melanoma/*therapy
Receptors, Antigen, T-Cell/*immunology
Skin Neoplasms/*immunology
Skin Neoplasms/*therapy
Animals ; Humans
SCR Disease Name :
Melanoma, Cutaneous Malignant
Czasopismo naukowe
Tytuł :
The T Cell Receptor Immune Repertoire Protects the Liver From Reconsitution.
Autorzy :
Liang Q; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
Hu Y; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
Zhang M; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
Lin C; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
Zhang W; Department of Pathology, The 971 Hospital of People's Liberation Army Navy, Qingdao, China.
Li Y; Department of Pathology, Qingdao Municipal Hospital, Qingdao, China.
Zhu P; Department of Gynaecology and Obstetrics, The 971 Hospital of People's Liberation Army Navy, Qingdao, China.
Xue P; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
Chen Y; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
Li Q; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
Wang K; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Dec 18; Vol. 11, pp. 584979. Date of Electronic Publication: 2020 Dec 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liver/*immunology
Receptors, Antigen, T-Cell/*immunology
Animals ; Hepatic Stellate Cells/immunology ; Liver Cirrhosis/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe

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