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Wyszukujesz frazę ""T cell receptor"" wg kryterium: Temat


Tytuł :
Comprehensive analysis of T-cell receptor repertoire in patients with acute coronary syndrome by high-throughput sequencing.
Autorzy :
Liu S; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China. .; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China. .
Zhong Z; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizho, 514031, P. R. China.; Center for Cardiovascular Diseases, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, 514031, P. R. China.
Zhong W; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizho, 514031, P. R. China.; Center for Cardiovascular Diseases, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, 514031, P. R. China.
Weng R; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
Liu J; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
Gu X; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
Chen Y; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
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Źródło :
BMC cardiovascular disorders [BMC Cardiovasc Disord] 2020 May 27; Vol. 20 (1), pp. 253. Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
High-Throughput Nucleotide Sequencing*
Acute Coronary Syndrome/*genetics
Angina, Unstable/*genetics
Myocardial Infarction/*genetics
T-Lymphocytes/*immunology
Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/immunology ; Aged ; Angina, Unstable/diagnosis ; Angina, Unstable/immunology ; Case-Control Studies ; China ; Complementarity Determining Regions/genetics ; Female ; Genes, T-Cell Receptor beta/genetics ; Humans ; Immunoglobulin Variable Region ; Male ; Middle Aged ; Myocardial Infarction/diagnosis ; Myocardial Infarction/immunology
Czasopismo naukowe
Tytuł :
Regulation of T-cell Receptor Gene Expression by Three-Dimensional Locus Conformation and Enhancer Function.
Autorzy :
Rodríguez-Caparrós A; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Álvarez-Santiago J; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Del Valle-Pastor MJ; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Suñé C; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
López-Ros J; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Hernández-Munain C; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 11; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Enhancer Elements, Genetic/*genetics
Gene Expression Regulation/*genetics
Genes, T-Cell Receptor/*genetics
T-Lymphocytes/*immunology
Animals ; Chromatin/genetics ; Chromatin/immunology ; Enhancer Elements, Genetic/immunology ; Gene Expression Regulation/immunology ; Genes, T-Cell Receptor/immunology ; Humans ; Signal Transduction/genetics ; Signal Transduction/immunology ; Transcription, Genetic/genetics ; Transcription, Genetic/immunology ; V(D)J Recombination/genetics ; V(D)J Recombination/immunology
Czasopismo naukowe
Tytuł :
The expansion of the TRB and TRG genes in domestic goats (Capra hircus) is characteristic of the ruminant species.
Autorzy :
Giannico F; Department of Veterinary Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Massari S; Department of Biological and Environmental Science and Technologies, University of Salento, Lecce, Italy.
Caputi Jambrenghi A; Department of Agricultural and Environmental Science, University of Bari 'Aldo Moro', Bari, Italy.
Soriano A; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Pala A; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Linguiti G; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Ciccarese S; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Antonacci R; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy. .
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Źródło :
BMC genomics [BMC Genomics] 2020 Sep 11; Vol. 21 (1), pp. 623. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Genes, T-Cell Receptor beta*
Genes, T-Cell Receptor gamma*
Goats/*genetics
Animals ; Gene Dosage ; Goats/classification ; Phylogeny
Czasopismo naukowe
Tytuł :
Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases.
Autorzy :
Rosati E; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Pogorelyy MV; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.
Dowds CM; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Moller FT; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Sorensen SB; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Lebedev YB; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.
Frey N; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany.
Schreiber S; Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany.
Spehlmann ME; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany.
Andersen V; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; IRS-Center Sønderjylland, University of Southern Denmark, Odense, Denmark.
Mamedov IZ; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.; Laboratory of molecular biology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.; CEITEC, Masaryk University, Brno, Czech Republic.
Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
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Źródło :
Journal of Crohn's & colitis [J Crohns Colitis] 2020 Jul 09; Vol. 14 (6), pp. 778-790.
Typ publikacji :
Journal Article; Twin Study
MeSH Terms :
Colitis, Ulcerative*/diagnosis
Colitis, Ulcerative*/immunology
Colitis, Ulcerative*/physiopathology
Crohn Disease*/diagnosis
Crohn Disease*/immunology
Crohn Disease*/physiopathology
Genes, T-Cell Receptor alpha*
Genes, T-Cell Receptor beta*
Receptors, Antigen, T-Cell, alpha-beta/*blood
Adult ; C-Reactive Protein/analysis ; Denmark ; Feces ; Female ; Germany ; Humans ; Leukocyte L1 Antigen Complex/analysis ; Male ; Patient Acuity ; Sequence Analysis, DNA ; Smoking/immunology ; Twins, Monozygotic
Czasopismo naukowe
Tytuł :
TCR-Seq Identifies Distinct Repertoires of Distant-Metastatic and Nondistant-Metastatic Thyroid Tumors.
Autorzy :
Lan X; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Cao J; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Ye K; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhang C; Geneplus-Shenzhen, Shenzhen, China.
Zhang Q; Zhejiang Chinese Medical University, Hangzhou, China.
Ge X; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.; Heartland Christian School, Columbiana, Ohio, USA.
Wang C; Geneplus-Shenzhen, Shenzhen, China.; School of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Zhang C; Geneplus-Beijing, Beijing, China.
Tai Z; Geneplus-Shenzhen, Shenzhen, China.
Wei W; Geneplus-Shenzhen, Shenzhen, China.
Huang Y; Geneplus-Shenzhen, Shenzhen, China.
Yi X; Geneplus-Shenzhen, Shenzhen, China.
Tan Z; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Zheng C; Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, China.
Chen C; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Zhu X; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Wang J; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Xu J; Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, China.
Zhu X; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Ge M; Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, China.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Sep 01; Vol. 105 (9).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Lymphocytes, Tumor-Infiltrating/*metabolism
Thyroid Cancer, Papillary/*genetics
Thyroid Cancer, Papillary/*pathology
Thyroid Neoplasms/*genetics
Thyroid Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Female ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; Retrospective Studies ; Thyroid Nodule/genetics ; Thyroid Nodule/pathology
Czasopismo naukowe
Tytuł :
Clinical and cytopathological characteristics of HTLV-1 hodgkin lymphoma.
Autorzy :
Kobata K; Division of Diagnostic Pathology, Faculty of Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Kimura S; Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Mihashi Y; Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.; Departments of Otolaryngology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Iwasaki H; Departments of Hematology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
Nonaka S; Departments of Pathology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
Matsumoto S; Division of Diagnostic Pathology, Faculty of Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Takamatsu Y; Division of Medical Oncology, Hematology and Infectious Diseases, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Choi I; Department of Hematology, National Hospital Organization, Kyushu Cancer Center, Fukuoka, Japan.
Kawauchi S; Departments of Pathology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
Ishitsuka K; Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.
Takeshita M; Division of Diagnostic Pathology, Faculty of Medicine, Fukuoka University Hospital, Fukuoka, Japan.; Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
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Źródło :
Cancer medicine [Cancer Med] 2020 Aug; Vol. 9 (16), pp. 5788-5797. Date of Electronic Publication: 2020 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor*
Genes, T-Cell Receptor beta*
Hodgkin Disease*/genetics
Hodgkin Disease*/mortality
Hodgkin Disease*/pathology
Human T-lymphotropic virus 1*/genetics
Leukemia-Lymphoma, Adult T-Cell*/genetics
Leukemia-Lymphoma, Adult T-Cell*/mortality
Leukemia-Lymphoma, Adult T-Cell*/pathology
Adult ; Aged ; Antigens, CD20/metabolism ; Cell Size ; DNA, Viral ; Epstein-Barr Virus Infections ; Female ; Humans ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Middle Aged ; Reed-Sternberg Cells ; Virus Integration/genetics
Czasopismo naukowe
Tytuł :
Diagnostic Value of Genotypic Analysis in Primary Cutaneous Lymphomas using Standardized BIOMED-2 Polymerase Chain Reaction Protocols: Experience in Daily Clinical Practice.
Autorzy :
LÓPEZ AVENTÍN, Daniel
GALLARDO, Fernando
COLOMO, Luis
MORAGÓN, Ester
VELA, María Carmen
DURAN JORDÀ, Xavier
BELLOSILLO, Beatriz
PUJOL, Ramon M.
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Źródło :
Acta Dermato-Venereologica. May2021, Vol. 101 Issue 5, p1-7. 7p.
Czasopismo naukowe
Tytuł :
IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.
Autorzy :
Pégorier P; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Bertignac M; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Chentli I; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Nguefack Ngoune V; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Folch G; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Jabado-Michaloud J; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Hadi-Saljoqi S; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Giudicelli V; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Duroux P; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Lefranc MP; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Kossida S; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 May 05; Vol. 11, pp. 821. Date of Electronic Publication: 2020 May 05 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Genetic Loci*
Computational Biology/*methods
Immunogenetics/*methods
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Animals ; Cats ; Databases, Genetic ; Dogs ; Ferrets/genetics ; Ferrets/immunology ; Humans ; Macaca mulatta/genetics ; Macaca mulatta/immunology ; Multigene Family ; Phylogeny ; Rabbits ; Sheep/genetics ; Sheep/immunology ; Swine/genetics ; Swine/immunology
Czasopismo naukowe
Tytuł :
T cell receptor gene recombinations in human tumor specimen exome files: detection of T cell receptor-β VDJ recombinations associates with a favorable oncologic outcome for bladder cancer.
Autorzy :
Samy MD; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA.
Tong WL; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA.
Yavorski JM; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA.
Sexton WJ; Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Blanck G; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA. .; Immunology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2017 Mar; Vol. 66 (3), pp. 403-410. Date of Electronic Publication: 2016 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Urinary Bladder Neoplasms/*genetics
V(D)J Recombination/*genetics
Exome ; Genes, T-Cell Receptor beta ; Humans ; Treatment Outcome ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Nodal EBV-positive polymorphic B cell lymphoproliferative disorder with plasma cell differentiation: clinicopathological analysis of five cases.
Autorzy :
Satou A; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan. .
Tabata T; Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
Suzuki Y; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Sato Y; Division of Pathophysiology, Okayama University Graduate School of Health Sciences, Okayama, Japan.
Tahara I; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Mochizuki K; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Oishi N; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Takahara T; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan.
Yoshino T; Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
Tsuzuki T; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan.
Nakamura S; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 May; Vol. 478 (5), pp. 969-976. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
B-Lymphocytes/*pathology
Epstein-Barr Virus Infections/*pathology
Herpesvirus 4, Human/*pathogenicity
Lymphoma, Large B-Cell, Diffuse/*pathology
Lymphoproliferative Disorders/*pathology
Plasma Cells/*pathology
Aged ; Aged, 80 and over ; Antirheumatic Agents/adverse effects ; B-Lymphocytes/immunology ; B-Lymphocytes/virology ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Diagnosis, Differential ; Epstein-Barr Virus Infections/genetics ; Epstein-Barr Virus Infections/immunology ; Epstein-Barr Virus Infections/virology ; Female ; Genes, Immunoglobulin Heavy Chain ; Genes, T-Cell Receptor gamma ; Herpesvirus 4, Human/genetics ; Herpesvirus 4, Human/immunology ; Host-Pathogen Interactions ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/immunology ; Lymphoma, Large B-Cell, Diffuse/virology ; Lymphoproliferative Disorders/genetics ; Lymphoproliferative Disorders/immunology ; Lymphoproliferative Disorders/virology ; Male ; Methotrexate/adverse effects ; Plasma Cells/immunology ; Plasma Cells/virology ; Predictive Value of Tests ; Risk Factors
Czasopismo naukowe
Tytuł :
High-throughput sequencing reveals the diversity of TCR β chain CDR3 repertoire in patients with severe acne.
Autorzy :
Shao L; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Liu Y; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Mei J; BGI Genomics, BGI-Shenzhen, Shenzhen 518083, PR China.
Li D; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, USA.
Chen L; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Pan Q; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Zhang S; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Dai X; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Liang J; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China. Electronic address: .
Sun S; BGI Genomics, BGI-Shenzhen, Shenzhen 518083, PR China. Electronic address: .
Wang J; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Apr; Vol. 120, pp. 23-31. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Acne Vulgaris/*genetics
Acne Vulgaris/*immunology
Complementarity Determining Regions/*genetics
Adolescent ; Amino Acid Sequence ; Base Sequence ; Genetic Variation ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Multiplex Polymerase Chain Reaction ; Sequence Analysis, DNA ; Sequence Analysis, Protein ; Young Adult
Czasopismo naukowe
Tytuł :
Differential Diagnosis of Interstitial Allograft Rejection and BKV Nephropathy by T-cell Receptor Sequencing.
Autorzy :
Stervbo U; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.
Nienen M; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Immunology, Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin, Germany.
Hecht J; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
Viebahn R; Department of Surgery, Ruhr-University Bochum, Knappschaftskrankenhaus, Bochum, Germany.
Amann K; Department Nephropathology, University Hospital Erlangen, Erlangen, Germany.
Westhoff TH; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.
Babel N; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
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Źródło :
Transplantation [Transplantation] 2020 Apr; Vol. 104 (4), pp. e107-e108.
Typ publikacji :
Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Sequence Analysis, DNA*
BK Virus/*pathogenicity
Graft Rejection/*diagnosis
Kidney Transplantation/*adverse effects
Opportunistic Infections/*diagnosis
Polyomavirus Infections/*diagnosis
Tumor Virus Infections/*diagnosis
BK Virus/immunology ; Diagnosis, Differential ; Graft Rejection/genetics ; Graft Rejection/immunology ; Graft Rejection/prevention & control ; High-Throughput Nucleotide Sequencing ; Humans ; Immunocompromised Host ; Immunosuppressive Agents/adverse effects ; Male ; Opportunistic Infections/genetics ; Opportunistic Infections/immunology ; Opportunistic Infections/virology ; Polyomavirus Infections/genetics ; Polyomavirus Infections/immunology ; Polyomavirus Infections/virology ; Predictive Value of Tests ; Treatment Outcome ; Tumor Virus Infections/genetics ; Tumor Virus Infections/immunology ; Tumor Virus Infections/virology ; Viral Load ; Young Adult
Raport
Tytuł :
Overview of the Germline and Expressed Repertoires of the TRB Genes in Sus scrofa .
Autorzy :
Massari S; Department of Biological and Environmental Science and Technologies, University of Salento, Lecce, Italy.
Bellini M; Department of Biology, University of Bari 'Aldo Moro', Bari, Italy.
Ciccarese S; Department of Biology, University of Bari 'Aldo Moro', Bari, Italy.
Antonacci R; Department of Biology, University of Bari 'Aldo Moro', Bari, Italy.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 Nov 05; Vol. 9, pp. 2526. Date of Electronic Publication: 2018 Nov 05 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta/*genetics
Receptors, Antigen, T-Cell, alpha-beta/*genetics
T-Lymphocytes/*immunology
Adaptive Immunity/genetics ; Adaptive Immunity/immunology ; Amino Acid Sequence/genetics ; Animals ; Genes, T-Cell Receptor alpha/genetics ; Genome/genetics ; Polymorphism, Single Nucleotide/genetics ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Sus scrofa ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Dissection of the Human T-Cell Receptor γ Gene Repertoire in the Brain and Peripheral Blood Identifies Age- and Alzheimer's Disease-Associated Clonotype Profiles.
Autorzy :
Aliseychik M; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.; Center for Genetics and Genetic Technologies, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Patrikeev A; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Gusev F; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Grigorenko A; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Andreeva T; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.; Center for Genetics and Genetic Technologies, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Biragyn A; Immunoregulation Section, National Institute on Aging, Baltimore, MD, United States.
Rogaev E; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.; Center for Genetics and Genetic Technologies, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Jan 29; Vol. 11, pp. 12. Date of Electronic Publication: 2020 Jan 29 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor gamma*
Aging/*blood
Aging/*immunology
Alzheimer Disease/*blood
Alzheimer Disease/*immunology
Brain/*immunology
Clone Cells/*immunology
Receptors, Antigen, T-Cell, gamma-delta/*genetics
Adult ; Aged ; Aged, 80 and over ; Complementarity Determining Regions/genetics ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Pilot Projects ; Receptors, Antigen, T-Cell, gamma-delta/blood ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
The Genome Resequencing of TCR Loci in Gallus gallus Revealed Their Distinct Evolutionary Features in Avians.
Autorzy :
Liu F; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Li J; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.; College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Lin IYC; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Yang X; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Ma J; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Chen Y; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Lv N; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Shi Y; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Gao GF; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Zhu B; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; .; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China; and.; Department of Pathogenic Biology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan 646000, China.
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Źródło :
ImmunoHorizons [Immunohorizons] 2020 Jan 28; Vol. 4 (1), pp. 33-46. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Receptors, Antigen, T-Cell/*genetics
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Receptors, Antigen, T-Cell, gamma-delta/*genetics
Animals ; Biological Evolution ; Chickens ; Chromosome Mapping ; Evolution, Molecular ; Genomics ; Phylogeny ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
Detection of neoantigen-reactive T cell clones based on the clonal expansion using next-generation sequencing of T cell receptor β complementarity-determining region 3.
Autorzy :
Sumimoto H; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan. Electronic address: .
Takano A; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address: .
Teramoto K; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan. Electronic address: .
Daigo Y; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2020 Jan; Vol. 476, pp. 112679. Date of Electronic Publication: 2019 Oct 23.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epitopes*
Genes, T-Cell Receptor beta*
High-Throughput Nucleotide Sequencing*
Antigens, Neoplasm/*immunology
Clone Cells/*immunology
Complementarity Determining Regions/*genetics
T-Lymphocytes/*immunology
Aged ; Cell Separation/methods ; Enzyme-Linked Immunospot Assay ; Female ; Humans ; Lung Neoplasms/immunology ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Two Successive Inversional Vβ Rearrangements on a Single Tcrb Allele Can Contribute to the TCRβ Repertoire.
Autorzy :
Lee KD; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Bassing CH; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Jan 01; Vol. 204 (1), pp. 78-86. Date of Electronic Publication: 2019 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor beta/*genetics
Alleles ; Animals ; Genes, T-Cell Receptor beta/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
A systematic analysis of immune genes and overall survival in cancer patients.
Autorzy :
Wang Q; Center for Public Health Informatics, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, People's Republic of China.
Li P; Center for Public Health Informatics, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, People's Republic of China. .
Wu W; Center for Public Health Informatics, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, People's Republic of China. .
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Źródło :
BMC cancer [BMC Cancer] 2019 Dec 16; Vol. 19 (1), pp. 1225. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Signal Transduction*
Neoplasms/*immunology
Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasms/diagnosis ; Neoplasms/genetics ; Neoplasms/metabolism ; Prognosis ; Survival Analysis
Czasopismo naukowe
Tytuł :
Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors.
Autorzy :
Mika J; Data Mining Division, Silesian University of Technology, Gliwice, Poland.
Kabacik S; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards Public Health England Chilton, Didcot, United Kingdom.
Badie C; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards Public Health England Chilton, Didcot, United Kingdom.
Polanska J; Data Mining Division, Silesian University of Technology, Gliwice, Poland.
Candéias SM; Université Grenoble Alpes, CEA, CNRS, IRIG-LCBM, Grenoble, France.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Nov 08; Vol. 10, pp. 2637. Date of Electronic Publication: 2019 Nov 08 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
V(D)J Recombination*
Animals ; DNA ; Humans ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred CBA ; VDJ Recombinases
Czasopismo naukowe
Tytuł :
Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy.
Autorzy :
Spear TT; Department of Surgery, Cardinal Bernardin Cancer Center, Loyola University Chicago, 2160 S. 1st Ave, Bldg 112, Room 308, Maywood, IL, 60153, USA. .
Evavold BD; Department of Pathology, Microbiology and Immunology, University of Utah, Salt Lake City, UT, 84112, USA.
Baker BM; Department of Chemistry and Biochemistry, Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, 46530, USA.
Nishimura MI; Department of Surgery, Cardinal Bernardin Cancer Center, Loyola University Chicago, 2160 S. 1st Ave, Bldg 112, Room 308, Maywood, IL, 60153, USA.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2019 Nov; Vol. 68 (11), pp. 1881-1889. Date of Electronic Publication: 2019 Oct 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunotherapy*
Cytotoxicity, Immunologic/*immunology
Genes, T-Cell Receptor/*immunology
Neoplasms/*therapy
T-Lymphocytes/*immunology
T-Lymphocytes/*transplantation
Animals ; Antibody Specificity ; Cross Reactions ; Genes, T-Cell Receptor/genetics ; Humans ; Neoplasms/immunology ; Neoplasms/metabolism ; T-Cell Antigen Receptor Specificity ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Tumor hypoxia represses γδ T cell-mediated antitumor immunity against brain tumors.
Autorzy :
Park JH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Kim HJ; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Kim CW; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Kim HC; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Jung Y; Department of Bio and Brain Engineering, KAIST, Daejeon, Republic of Korea.
Lee HS; Department of Bio and Brain Engineering, KAIST, Daejeon, Republic of Korea.
Lee Y; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Ju YS; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.; BioMedical Research Center, KAIST, Daejeon, Republic of Korea.
Oh JE; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.; BioMedical Research Center, KAIST, Daejeon, Republic of Korea.
Park SH; Department of Bio and Brain Engineering, KAIST, Daejeon, Republic of Korea.
Lee JH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.; BioMedical Research Center, KAIST, Daejeon, Republic of Korea.
Lee SK; Department of Obstetrics and Gynecology, College of Medicine, Myunggok Medical Research Center, Konyang University, Daejeon, Republic of Korea.
Lee HK; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea. .; BioMedical Research Center, KAIST, Daejeon, Republic of Korea. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Mar; Vol. 22 (3), pp. 336-346. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytotoxicity, Immunologic*
Tumor Escape*
Tumor Microenvironment*
Brain Neoplasms/*immunology
Glioblastoma/*immunology
Intraepithelial Lymphocytes/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Animals ; Apoptosis ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; CD8 Antigens/genetics ; CD8 Antigens/metabolism ; Cell Line, Tumor ; Coculture Techniques ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Gene Expression Regulation, Neoplastic ; Genes, T-Cell Receptor delta ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Intraepithelial Lymphocytes/metabolism ; Intraepithelial Lymphocytes/pathology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, Nude ; NK Cell Lectin-Like Receptor Subfamily K/genetics ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Phenotype ; Signal Transduction ; Tumor Hypoxia
Czasopismo naukowe
Tytuł :
Absence of αβ T cells accelerates disuse bone loss in male mice after spinal cord injury.
Autorzy :
Sahbani K; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.
Shultz LC; Veterinary Medical Unit, James J Peters Veterans Affairs Medical Center, Bronx, New York.
Cardozo CP; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.; Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.; Department of Rehabilitation Medicine and Human Performance, The Icahn School of Medicine at Mount Sinai, New York, New York.
Bauman WA; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.; Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.
Tawfeek HA; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.; Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.
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Źródło :
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2021 Mar; Vol. 1487 (1), pp. 43-55. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Resorption/*genetics
Genes, T-Cell Receptor beta/*genetics
Spinal Cord Injuries/*complications
T-Lymphocytes/*pathology
Animals ; Bone Density/genetics ; Bone Density/immunology ; Bone Diseases, Metabolic/genetics ; Bone Diseases, Metabolic/immunology ; Bone Diseases, Metabolic/metabolism ; Bone Diseases, Metabolic/pathology ; Bone Resorption/immunology ; Bone Resorption/metabolism ; Cell Count ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Antigen, T-Cell, alpha-beta/deficiency ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; Spinal Cord Injuries/genetics ; Spinal Cord Injuries/immunology ; Spinal Cord Injuries/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; X-Ray Microtomography
Czasopismo naukowe
Tytuł :
Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells.
Autorzy :
Schoettler N; 1Department of Medicine, The University of Chicago, Chicago, USA.; 2Department of Human Genetics, The University of Chicago, Chicago, USA.
Hrusch CL; 1Department of Medicine, The University of Chicago, Chicago, USA.
Blaine KM; 1Department of Medicine, The University of Chicago, Chicago, USA.
Sperling AI; 1Department of Medicine, The University of Chicago, Chicago, USA.
Ober C; 2Department of Human Genetics, The University of Chicago, Chicago, USA.
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Źródło :
Communications biology [Commun Biol] 2019 Nov 13; Vol. 2, pp. 411. Date of Electronic Publication: 2019 Nov 13 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor*
Immunologic Memory*
Transcription, Genetic*
Lung/*immunology
Lymph Nodes/*immunology
T-Lymphocyte Subsets/*immunology
T-Lymphocyte Subsets/*metabolism
Biomarkers ; Cellular Reprogramming/genetics ; Gene Expression Profiling ; Gene Ontology ; Humans ; Immunophenotyping ; Reproducibility of Results ; V(D)J Recombination
Czasopismo naukowe
Tytuł :
TCRα reporter mice reveal contribution of dual TCRα expression to T cell repertoire and function.
Autorzy :
Yang L; Department of Pathology, University of California San Diego, La Jolla, CA 92093.
Jama B; Department of Pathology, University of California San Diego, La Jolla, CA 92093.
Wang H; Department of Pathology, University of California San Diego, La Jolla, CA 92093.
Labarta-Bajo L; Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093.
Zúñiga EI; Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093.
Morris GP; Department of Pathology, University of California San Diego, La Jolla, CA 92093; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 22; Vol. 117 (51), pp. 32574-32583. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor alpha/*physiology
Lymphocytic Choriomeningitis/*immunology
T-Lymphocytes/*physiology
Animals ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/physiology ; CD4-Positive T-Lymphocytes/virology ; CD5 Antigens/immunology ; CD5 Antigens/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/virology ; Chlorocebus aethiops ; Female ; Gene Expression ; Green Fluorescent Proteins/genetics ; Immunologic Memory/genetics ; Lymphocytic choriomeningitis virus/pathogenicity ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Thymocytes/immunology ; Thymocytes/physiology ; Vero Cells
Czasopismo naukowe
Tytuł :
Dimorphism in the T-cell receptor constant region affects T-cell function, phenotype and HIV outcome.
Autorzy :
Kaewpreedee P; Interdisciplinary Program in Medical Microbiology, Graduate School, Chulalongkorn University.; Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital.
Boonrat P; Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital.; Department of Biology, Faculty of Science, Chulalongkorn University.
Tansiri Y; Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital.; Faculty of Medicine, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.
Rowland-Jones SL; Nuffield Department of Medicine, NDM Research Building, University of Oxford, Old Road Campus, Oxford, UK.
Hansasuta P; Interdisciplinary Program in Medical Microbiology, Graduate School, Chulalongkorn University.; Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital.; Nuffield Department of Medicine, NDM Research Building, University of Oxford, Old Road Campus, Oxford, UK.
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Źródło :
AIDS (London, England) [AIDS] 2019 Jul 15; Vol. 33 (9), pp. 1421-1429.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Genetic Variation*
CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*immunology
Receptors, Antigen, T-Cell, alpha-beta/*genetics
T-Lymphocyte Subsets/*immunology
Adult ; Cross-Sectional Studies ; Cytomegalovirus/immunology ; Cytomegalovirus Infections/immunology ; Female ; HIV/immunology ; Humans ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant.
Autorzy :
Chapuis AG; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.
Egan DN; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.
Bar M; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.
Schmitt TM; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
McAfee MS; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Paulson KG; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.
Voillet V; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Gottardo R; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Ragnarsson GB; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Landspítali Háskólasjúkrahús, Reykjavík, Iceland.
Bleakley M; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.
Yeung CC; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.
Muhlhauser P; University of Washington School of Medicine, Seattle, WA, USA.
Nguyen HN; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Alpine Biotech, Seattle, WA, USA.
Kropp LA; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Therapeutic Products Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Castelli L; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Therapeutic Products Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Wagener F; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Hunter D; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Lindberg M; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; School of Informatics, University of Edinburgh, Edinburgh, UK.
Cohen K; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Seese A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
McElrath MJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; University of Washington School of Medicine, Seattle, WA, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Duerkopp N; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Gooley TA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Greenberg PD; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .; University of Washington School of Medicine, Seattle, WA, USA. .; Departments of Immunology and Medicine, University of Washington, Seattle, WA, USA. .
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Źródło :
Nature medicine [Nat Med] 2019 Jul; Vol. 25 (7), pp. 1064-1072. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Graft vs Host Disease/*prevention & control
Hematopoietic Stem Cell Transplantation/*adverse effects
Leukemia, Myeloid, Acute/*therapy
WT1 Proteins/*genetics
Adult ; Aged ; Female ; Humans ; Leukemia, Myeloid, Acute/mortality ; Male ; Middle Aged ; Recurrence ; Transplantation, Homologous
Czasopismo naukowe
Tytuł :
A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days.
Autorzy :
Kobayashi E; 1] Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan. [2].
Mizukoshi E
Kishi H
Ozawa T
Hamana H
Nagai T
Nakagawa H
Jin A
Kaneko S
Muraguchi A
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Źródło :
Nature medicine [Nat Med] 2013 Nov; Vol. 19 (11), pp. 1542-6. Date of Electronic Publication: 2013 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Genes, T-Cell Receptor*
Cloning, Molecular/*methods
Neoplasms/*genetics
Neoplasms/*immunology
Antigens, Neoplasm/metabolism ; Cancer Vaccines/genetics ; Cancer Vaccines/immunology ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/therapy ; Gene Expression ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Genetic Therapy ; Herpesvirus 4, Human/immunology ; Humans ; Immunotherapy ; Liver Neoplasms/genetics ; Liver Neoplasms/immunology ; Liver Neoplasms/therapy ; Molecular Sequence Data ; Neoplasms/therapy ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes, Cytotoxic/immunology ; alpha-Fetoproteins/genetics ; alpha-Fetoproteins/immunology
Czasopismo naukowe
Tytuł :
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems.
Autorzy :
Chen Z; Departments of Pathology.
Wang M; Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Guan P; Departments of Pathology.
Zhao S; Departments of Pathology.
Zhang W; Departments of Pathology.
Gao L; Departments of Pathology.
Tang Y; Departments of Pathology.
Li L; Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Liu W; Departments of Pathology.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2020 Aug; Vol. 44 (8), pp. 1061-1072.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epstein-Barr Virus Infections/*classification
Herpesvirus 4, Human/*genetics
Killer Cells, Natural/*immunology
Lymphoproliferative Disorders/*classification
T-Lymphocytes/*immunology
Adolescent ; Adult ; Age of Onset ; Cell Proliferation ; Child ; Child, Preschool ; China ; Databases, Factual ; Epstein-Barr Virus Infections/immunology ; Epstein-Barr Virus Infections/pathology ; Epstein-Barr Virus Infections/virology ; Female ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Humans ; Infant ; Killer Cells, Natural/pathology ; Lymphoproliferative Disorders/immunology ; Lymphoproliferative Disorders/pathology ; Lymphoproliferative Disorders/virology ; Male ; Middle Aged ; Prognosis ; RNA, Viral/genetics ; Retrospective Studies ; Risk Assessment ; Risk Factors ; T-Lymphocytes/pathology ; Time Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Histopathologic Characterization of Mogamulizumab-associated Rash.
Autorzy :
Wang JY; Department of Dermatology, Stanford University School of Medicine, Redwood City.; Department of Pathology.
Hirotsu KE; Department of Dermatology, Stanford University School of Medicine, Redwood City.
Neal TM; Department of Dermatology, Stanford University School of Medicine, Redwood City.
Raghavan SS; Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA.
Kwong BY; Department of Dermatology, Stanford University School of Medicine, Redwood City.
Khodadoust MS; Department of Dermatology, Stanford University School of Medicine, Redwood City.; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA.
Brown RA; Department of Dermatology, Stanford University School of Medicine, Redwood City.; Department of Pathology.
Novoa RA; Department of Dermatology, Stanford University School of Medicine, Redwood City.; Department of Pathology.
Kim YH; Department of Dermatology, Stanford University School of Medicine, Redwood City.; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA.
Rieger KE; Department of Dermatology, Stanford University School of Medicine, Redwood City.; Department of Pathology.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2020 Dec; Vol. 44 (12), pp. 1666-1676.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal, Humanized/*adverse effects
Antineoplastic Agents/*adverse effects
Drug Eruptions/*etiology
Exanthema/*chemically induced
Skin/*drug effects
T-Lymphocytes/*drug effects
CD4-CD8 Ratio ; Drug Eruptions/genetics ; Drug Eruptions/immunology ; Drug Eruptions/pathology ; Exanthema/genetics ; Exanthema/immunology ; Exanthema/pathology ; Female ; Genes, T-Cell Receptor ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Skin/immunology ; Skin/pathology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
High-throughput analysis of the T cell receptor gene repertoire in low-count monoclonal B cell lymphocytosis reveals a distinct profile from chronic lymphocytic leukemia.
Autorzy :
Agathangelidis A; Strategic Research Program on CLL and B-cell neoplasia Unit, Div. of Experimental Oncology, Milan.
Galigalidou C; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Scarfò L; Strategic Research Program on CLL and B-cell neoplasia Unit, Div. of Experimental Oncology, Milan.
Moysiadis T; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Rovida A; Strategic Research Program on CLL and B-cell neoplasia Unit, Div. of Experimental Oncology, Milan.
Vlachonikola E; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Sofou E; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Psomopoulos F; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Vardi A; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Ranghetti P; Strategic Research Program on CLL and B-cell neoplasia Unit, Div. of Experimental Oncology, Milan.
Siorenta A; Immunology and National Tissue Typing Center, General Hospital of Athens 'G. Gennimatas', Athens.
Galanis A; Department of Molecular Biology and Genetics (MBG), Democritus University of Thrace, Alexandroupolis.
Stamatopoulos K; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Chatzidimitriou A; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.
Ghia P; Strategic Research Program on CLL and B-cell neoplasia Unit, Div. of Experimental Oncology, Milan.
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Źródło :
Haematologica [Haematologica] 2020 Oct 01; Vol. 105 (10), pp. e515. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Lymphocytic, Chronic, B-Cell*/genetics
Lymphocytosis*/diagnosis
Lymphocytosis*/genetics
B-Lymphocytes ; Genes, T-Cell Receptor ; Humans ; Lymphocyte Count
Raport
Tytuł :
Relationship between T cell receptor clonotype and PD-1 expression of tumor-infiltrating lymphocytes in colorectal cancer.
Autorzy :
Sukegawa K; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Shitaoka K; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Hamana H; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Kobayashi E; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Miyahara Y; Department of Personalized Cancer Immunotherapy, Mie University Graduate School of Medicine, Mie, Japan.
Fujii K; Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan.
Tsuda K; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.; Department of Obstetrics and Gynecology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Saeki S; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Nagata T; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Ozawa T; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Saito S; Department of Obstetrics and Gynecology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Fujii T; Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Muraguchi A; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Shiku H; Department of Personalized Cancer Immunotherapy, Mie University Graduate School of Medicine, Mie, Japan.
Kishi H; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
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Źródło :
European journal of immunology [Eur J Immunol] 2020 Oct; Vol. 50 (10), pp. 1580-1590. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*immunology
CD8-Positive T-Lymphocytes/*immunology
Colorectal Neoplasms/*immunology
Immunotherapy, Adoptive/*methods
Lymphocytes, Tumor-Infiltrating/*metabolism
Programmed Cell Death 1 Receptor/*metabolism
Aged ; Aged, 80 and over ; Breast Neoplasms/therapy ; Clone Cells ; Colorectal Neoplasms/therapy ; Female ; Genes, T-Cell Receptor beta ; Humans ; Lymphocytes, Tumor-Infiltrating/immunology ; Male ; Middle Aged ; Programmed Cell Death 1 Receptor/genetics ; Receptors, Antigen, T-Cell/genetics
Czasopismo naukowe
Tytuł :
Deficiency of Mucosal-Associated Invariant T Cells in TCRJα18 Germline Knockout Mice.
Autorzy :
Xie J; Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710.; School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Pan Y; School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Tao H; Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710.
Wang P; Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710.
Chen Y; Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Gao J; School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; .
Zhong XP; Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710; .; Department of Immunology, Duke University Medical Center, Durham, NC 27710; and.; Hematologic Malignancies and Cellular Therapies Program, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710.
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Źródło :
ImmunoHorizons [Immunohorizons] 2019 Jun 11; Vol. 3 (6), pp. 203-207. Date of Electronic Publication: 2019 Jun 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor alpha*
Mucosal-Associated Invariant T Cells/*immunology
Mucous Membrane/*immunology
Natural Killer T-Cells/*immunology
Receptors, Antigen, T-Cell, alpha-beta/*physiology
Adoptive Transfer ; Animals ; Cells, Cultured ; Cytokines/metabolism ; Germ-Line Mutation ; Humans ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell, alpha-beta/genetics
Czasopismo naukowe
Tytuł :
Divergent Evolution of TRC Genes in Mammalian Niche Adaptation.
Autorzy :
Zhang Z; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Mu Y; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Shan L; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Sun D; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Guo W; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Yu Z; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Tian R; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Xu S; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
Yang G; Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Apr 24; Vol. 10, pp. 871. Date of Electronic Publication: 2019 Apr 24 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptation, Biological*
Evolution, Molecular*
Genes, T-Cell Receptor*
Genetic Variation*
Animals ; Ecosystem ; Genome ; Genomics/methods ; Mammals ; Phylogeny ; Selection, Genetic ; Species Specificity
Czasopismo naukowe
Tytuł :
High-throughput sequencing of the T-cell receptor β chain gene distinguishes 2 subgroups of cutaneous T-cell lymphoma.
Autorzy :
Wang J; Division of Hematology and Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: .
Rea B; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Pennsylvania.
Haun P; Department of Dermatology and Dermatopathology, Penn Cutaneous Lymphoma Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Emerson R; Adaptive Biotechnologies, Seattle, Washington.
Kirsch I; Adaptive Biotechnologies, Seattle, Washington.
Bagg A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Pennsylvania.
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Źródło :
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2019 Apr; Vol. 80 (4), pp. 1148-1150.e1. Date of Electronic Publication: 2018 Oct 23.
Typ publikacji :
Letter
MeSH Terms :
Genes, T-Cell Receptor beta*
Lymphoma, T-Cell, Cutaneous/*blood
Lymphoma, T-Cell, Cutaneous/*genetics
Skin Neoplasms/*blood
Skin Neoplasms/*genetics
Aged ; Clone Cells/pathology ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Lymphoma, T-Cell, Cutaneous/pathology ; Male ; Middle Aged ; Prognosis ; Skin Neoplasms/pathology ; Tumor Burden
Opinia redakcyjna
Tytuł :
Functional and T Cell Receptor Repertoire Analyses of Peripheral Blood and Infrapatellar Fat Pad T Cells in Knee Osteoarthritis.
Autorzy :
Sae-Jung T; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University.
Sengprasert P; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University.
Apinun J; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University.
Ngarmukos S; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University.
Yuktanandana P; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University.
Tanavalee A; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University.
Reantragoon R; From the Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. .; T. Sae-jung, BS, Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University; P. Sengprasert, MS, Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University; J. Apinun, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; S. Ngarmukos, MD, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; P. Yuktanandana, MD, Associate Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; A. Tanavalee, MD, Professor of Orthopedics, Department of Orthopedics, Faculty of Medicine, Chulalongkorn University; R. Reantragoon, MD, PhD, Lecturer in Immunology, Immunology Division, Department of Microbiology, Faculty of Medicine, and Center of Excellence in Immunology and Immune-mediated Diseases, Faculty of Medicine, Chulalongkorn University. .
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Źródło :
The Journal of rheumatology [J Rheumatol] 2019 Mar; Vol. 46 (3), pp. 309-317. Date of Electronic Publication: 2018 Oct 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Adipose Tissue/*pathology
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Osteoarthritis, Knee/*blood
Osteoarthritis, Knee/*pathology
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Aged ; Cytokines/analysis ; Cytotoxicity, Immunologic ; Female ; Humans ; Knee Joint/pathology ; Lymphocyte Activation ; Male ; Middle Aged ; Multiplex Polymerase Chain Reaction ; Osteoarthritis, Knee/immunology
Czasopismo naukowe
Tytuł :
High-Grade Epstein-Barr Virus-Negative Biphenotypic Lymphoma with Expression of B- and T-Cell Markers and Leukemia Presentation: Case Report and Literature Review.
Autorzy :
Kohla, Samah (AUTHOR)
Ibrahim, Feryal A. (AUTHOR)
Mudawi, Deena (AUTHOR)
Akiki, Susanna (AUTHOR)
Soliman, Dina (AUTHOR)
Al-Sabbagh, Ahmad (AUTHOR)
Youssef, Reda R.H. (AUTHOR)
Yassin, Mohamed A. (AUTHOR)
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Źródło :
Case Reports in Oncology. 2020, Vol. 13 Issue 3, p1215-1226. 12p.
Czasopismo naukowe
Tytuł :
Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
Autorzy :
Klarenbeek PL; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Laboratory for Genome Analysis, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Doorenspleet ME; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Laboratory for Genome Analysis, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Esveldt RE; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
van Schaik BD; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam, The Netherlands.
Lardy N; Department of Immunogenetics, Sanquin Diagnostic Services, Amsterdam, The Netherlands.
van Kampen AH; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam, The Netherlands.
Tak PP; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Plenge RM; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.
Baas F; Laboratory for Genome Analysis, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
de Bakker PI; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands; Department of Medical Genetics, University Medical Center, Utrecht, The Netherlands.
de Vries N; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło :
PloS one [PLoS One] 2015 Oct 30; Vol. 10 (10), pp. e0140815. Date of Electronic Publication: 2015 Oct 30 (Print Publication: 2015).
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor/*genetics
HLA Antigens/*genetics
CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Cell Differentiation/genetics ; Cell Lineage/genetics ; Genes, T-Cell Receptor alpha/genetics ; Genes, T-Cell Receptor beta/genetics ; Genetic Variation ; Humans ; Receptors, Antigen, T-Cell/genetics
Czasopismo naukowe
Tytuł :
Specific T-cell receptor gene transfer enhances immune response: A potential therapeutic strategy for the control of human cytomegalovirus infection in immunocompromised patients.
Autorzy :
Zhang R; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Zhang Y; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Hu J; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Wu W; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Chen X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Lu Z; Department of Radiotherapy, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Yang R; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Huang Y; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China.
Fan J; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, P.R. China. Electronic address: .
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Źródło :
Cellular immunology [Cell Immunol] 2019 Feb; Vol. 336, pp. 58-65. Date of Electronic Publication: 2019 Jan 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Genetic Therapy*
Cytomegalovirus Infections/*therapy
Adolescent ; Adult ; Cytomegalovirus Infections/immunology ; Humans ; Immunocompromised Host ; Interferon-gamma/biosynthesis ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
A rare population of tumor antigen-specific CD4 double-positive αβ T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells.
Autorzy :
Matsuzaki J; Center for Immunotherapy, Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, USA.
Tsuji T; Center for Immunotherapy, Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, USA. .
Chodon T; Center for Immunotherapy, Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, USA.
Ryan C; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, USA.
Koya RC; Center for Immunotherapy, Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, USA.
Odunsi K; Center for Immunotherapy, Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, USA. .; Center for Immunotherapy, Department of Immunology, Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, USA. .
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Źródło :
Journal for immunotherapy of cancer [J Immunother Cancer] 2019 Jan 09; Vol. 7 (1), pp. 7. Date of Electronic Publication: 2019 Jan 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Antigens, Neoplasm/*immunology
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
T-Lymphocyte Subsets/*immunology
Animals ; Cell Line, Tumor ; Cell Survival ; Humans ; Mice ; Receptors, Antigen, T-Cell
Czasopismo naukowe
Tytuł :
Comparative Study of the Clinical Pathology, Immunophenotype, Epstein-Barr Virus Infection Status, and Gene Rearrangements in Adult and Child Patients With Hydroa Vacciniforme-Like Lymphoproliferative Disorder.
Autorzy :
Wen PF; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhang M; Department of Dermatology, The Second People's Hospital of Chengdu, Cheng du, China.
Wang TT; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Liu HJ; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhang WY; Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Liu WP; Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang L; Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
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Źródło :
The American Journal of dermatopathology [Am J Dermatopathol] 2019 Jan; Vol. 41 (1), pp. 7-15.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor*
Genes, T-Cell Receptor gamma*
Skin*/immunology
Skin*/pathology
Skin*/virology
Epstein-Barr Virus Infections/*diagnosis
Facial Dermatoses/*diagnosis
Herpesvirus 4, Human/*isolation & purification
Hydroa Vacciniforme/*diagnosis
Lymphoma/*diagnosis
Adolescent ; Adult ; Age Factors ; Child ; Epstein-Barr Virus Infections/genetics ; Epstein-Barr Virus Infections/immunology ; Epstein-Barr Virus Infections/virology ; Facial Dermatoses/genetics ; Facial Dermatoses/immunology ; Facial Dermatoses/virology ; Female ; Genetic Markers ; Genetic Predisposition to Disease ; Humans ; Hydroa Vacciniforme/genetics ; Hydroa Vacciniforme/immunology ; Hydroa Vacciniforme/virology ; Immunohistochemistry ; Immunophenotyping/methods ; In Situ Hybridization, Fluorescence ; Lymphoma/genetics ; Lymphoma/immunology ; Lymphoma/virology ; Male ; Mast Cells/immunology ; Mast Cells/pathology ; Mast Cells/virology ; Middle Aged ; Phenotype ; Polymerase Chain Reaction ; Retrospective Studies ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
A Potential Mechanism of Anticancer Immune Response Coincident With Immune-related Adverse Events in Patients With Renal Cell Carcinoma.
Autorzy :
Kato T; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan .; Department of Urological Immuno-oncology, Osaka University Graduate School of Medicine, Osaka, Japan.
Tomiyama E; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Koh Y; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Matsushita M; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Hayashi Y; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Nakano K; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Ishizuya YU; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Wang C; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Hatano K; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Kawashima A; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Ujike T; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Kawasaki K; Department of Pathology, Osaka University Graduate School of Medicine, Osaka, Japan.
Morii E; Department of Pathology, Osaka University Graduate School of Medicine, Osaka, Japan.
Gotoh K; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Eguchi H; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Kiyotani K; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.
Fujita K; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Nonomura N; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.
Uemura M; Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.; Department of Urological Immuno-oncology, Osaka University Graduate School of Medicine, Osaka, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2020 Sep; Vol. 40 (9), pp. 4875-4883.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Renal Cell/*immunology
Carcinoma, Renal Cell/*therapy
Immunotherapy/*adverse effects
Kidney Neoplasms/*immunology
Kidney Neoplasms/*therapy
Aged ; Antineoplastic Agents, Immunological/adverse effects ; Drug-Related Side Effects and Adverse Reactions/immunology ; Female ; Gene Expression Profiling ; Genes, T-Cell Receptor/genetics ; Humans ; Leukocytes, Mononuclear/metabolism ; Male ; Middle Aged ; T-Lymphocyte Subsets/immunology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma.
Autorzy :
Rea B; Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Haun P; Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Emerson R; Adaptive Biotechnologies, Seattle, Washington, USA.
Vignali M; Adaptive Biotechnologies, Seattle, Washington, USA.
Farooqi M; Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Samimi S; Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Elenitsas R; Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kirsch I; Adaptive Biotechnologies, Seattle, Washington, USA.
Bagg A; Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2018 Sep; Vol. 71 (9), pp. 814-820. Date of Electronic Publication: 2018 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor beta*
Genes, T-Cell Receptor gamma*
High-Throughput Nucleotide Sequencing*
Biomarkers, Tumor/*genetics
Lymphoma, T-Cell, Cutaneous/*genetics
Skin Neoplasms/*genetics
Biopsy ; Clone Cells ; Diagnosis, Differential ; Flow Cytometry ; Genetic Predisposition to Disease ; Humans ; Lymphoma, T-Cell, Cutaneous/immunology ; Lymphoma, T-Cell, Cutaneous/pathology ; Phenotype ; Polymerase Chain Reaction ; Predictive Value of Tests ; Reproducibility of Results ; Skin Neoplasms/immunology ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub.
Autorzy :
Shih HY; Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Verma-Gaur J
Torkamani A
Feeney AJ
Galjart N
Krangel MS
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Dec 11; Vol. 109 (50), pp. E3493-502. Date of Electronic Publication: 2012 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor alpha*
V(D)J Recombination*
Chromatin/*genetics
Chromatin/*immunology
Repressor Proteins/*genetics
Animals ; Base Sequence ; CCCTC-Binding Factor ; DNA Primers/genetics ; Enhancer Elements, Genetic ; Genes, T-Cell Receptor delta ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Models, Genetic ; Models, Immunological ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Immunoglobulin and T cell receptor genes in Chinese crocodile lizard Shinisaurus crocodilurus.
Autorzy :
Gambón-Deza F; Immunology Unit, Hospital of Meixoiero, Vigo, Spain. Electronic address: .
Olivieri DN; School of Computer Science, University of Vigo, Ourense 32004, Spain. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2018 Sep; Vol. 101, pp. 160-166. Date of Electronic Publication: 2018 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, Immunoglobulin*
Genes, T-Cell Receptor*
Lizards/*genetics
Amino Acid Sequence ; Animals ; Exons/genetics ; Phylogeny
Czasopismo naukowe
Tytuł :
Ultrasensitive DNA Immune Repertoire Sequencing Using Unique Molecular Identifiers.
Autorzy :
Johansson G; Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.; Translational Science & Experimental Medicine, Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA), Gothenburg, Sweden.
Kaltak M; Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Rîmniceanu C; Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 7A, University of Gothenburg, Gothenburg, Sweden.
Singh AK; Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 7A, University of Gothenburg, Gothenburg, Sweden.
Lycke J; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Malmeström C; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Hühn M; Translational Science & Experimental Medicine, Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA), Gothenburg, Sweden.
Vaarala O; Respiratory Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
Cardell S; Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 7A, University of Gothenburg, Gothenburg, Sweden.
Ståhlberg A; Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.
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Źródło :
Clinical chemistry [Clin Chem] 2020 Sep 01; Vol. 66 (9), pp. 1228-1237.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA/*analysis
Intraepithelial Lymphocytes/*classification
Base Sequence ; DNA/genetics ; Genes, T-Cell Receptor delta ; Humans ; Intraepithelial Lymphocytes/chemistry ; Polymerase Chain Reaction/methods ; Reproducibility of Results ; Sequence Analysis, DNA/methods
Czasopismo naukowe
Tytuł :
Conventional and Computational Flow Cytometry Analyses Reveal Sustained Human Intrathymic T Cell Development From Birth Until Puberty.
Autorzy :
Lavaert M; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Valcke B; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Vandekerckhove B; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Leclercq G; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Liang KL; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Taghon T; Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Aug 04; Vol. 11, pp. 1659. Date of Electronic Publication: 2020 Aug 04 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Flow Cytometry*
Immunophenotyping*
Puberty*
Thymocytes/*immunology
Thymus Gland/*immunology
Adolescent ; Adolescent Development ; Age Factors ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; Biomarkers/metabolism ; Cell Lineage ; Child ; Child Development ; Child, Preschool ; Cluster Analysis ; Gene Expression Regulation, Developmental ; Genes, T-Cell Receptor ; Humans ; Infant ; Infant, Newborn ; Phenotype ; Thymocytes/metabolism ; Thymus Gland/cytology ; Thymus Gland/metabolism
Czasopismo naukowe
Tytuł :
Inefficient V(D)J recombination underlies monogenic T cell receptor β expression.
Autorzy :
Wu GS; Immunology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Bassing CH; Immunology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; .; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 04; Vol. 117 (31), pp. 18172-18174. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
V(D)J Recombination*
Genes, T-Cell Receptor beta/*physiology
Animals ; Female ; Gene Expression Regulation/physiology ; Heterozygote ; Male ; Mice ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
Refractory celiac disease type II: An atypical case highlighting limitations of the current classification system.
Autorzy :
Soderquist CR; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
Hsiao S; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
Mansukhani MM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
Alobeid B; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
Green PH; Department of Medicine, Celiac Disease Center, Columbia University Irving Medical Center, New York, New York, USA.
Bhagat G; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
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Źródło :
Hematological oncology [Hematol Oncol] 2020 Aug; Vol. 38 (3), pp. 399-405. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Case Reports
MeSH Terms :
Gene Rearrangement*
Biomarkers/*analysis
Celiac Disease/*classification
Celiac Disease/*pathology
Genes, T-Cell Receptor beta/*genetics
Immunophenotyping/*standards
Aged ; Celiac Disease/genetics ; Celiac Disease/metabolism ; High-Throughput Nucleotide Sequencing ; Humans ; Male
Raport
Tytuł :
Paradoxical prognostic phenomenon of plasma T-cell-derived circulating DNA level in advanced non-small cell lung cancer.
Autorzy :
Sitthideatphaiboon P; Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand.
Santisukwongchote S; Department of Pathology, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand.
Khunsri S; Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand.
Sathitruangsak C; Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand.; Holistic Center for Cancer Study and Care (HOCC-PSU) and Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
Chantranuwat P; Department of Pathology, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand.
Vinayanuwattikun C; Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand. .
Sriuranpong V; Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and The King Chulalongkorn Memorial Hospital, 1873 Rama IV road, Pathumwan, Bangkok, 10330, Thailand.
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Źródło :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2020 Jul; Vol. 22 (7), pp. 1117-1125. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*blood
Carcinoma, Non-Small-Cell Lung/*blood
Cell-Free Nucleic Acids/*blood
Lung Neoplasms/*blood
Lymphocytes, Tumor-Infiltrating/*metabolism
T-Lymphocytes/*metabolism
Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; CD3 Complex ; CD8 Antigens ; CD8-Positive T-Lymphocytes/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell-Free Nucleic Acids/metabolism ; Female ; Functional Status ; Genes, T-Cell Receptor beta ; Humans ; Immunohistochemistry ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Prognosis ; Survival Rate
Czasopismo naukowe
Tytuł :
T Cell Receptor Alpha Chain Genes in the Teleost Ballan Wrasse (Labrus bergylta) Are Subjected to Somatic Hypermutation.
Autorzy :
Bilal S; Department of Biological Sciences, University of Bergen, Bergen, Norway.
Lie KK; Institute of Marine Research (IMR), Bergen, Norway.
Sæle Ø; Institute of Marine Research (IMR), Bergen, Norway.
Hordvik I; Department of Biological Sciences, University of Bergen, Bergen, Norway.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 May 22; Vol. 9, pp. 1101. Date of Electronic Publication: 2018 May 22 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor alpha*
Somatic Hypermutation, Immunoglobulin*
Fishes/*genetics
Amino Acid Sequence ; Animals ; Chromosome Mapping ; Computational Biology/methods ; DNA, Complementary ; Genome ; Genomics/methods ; High-Throughput Nucleotide Sequencing ; Mutation ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
T-cell repertoires in refractory coeliac disease.
Autorzy :
Ritter J; Institute of Pathology, Charité-University Medicine, Berlin, Germany.
Zimmermann K; Institute of Pathology, Charité-University Medicine, Berlin, Germany.
Jöhrens K; Institute of Pathology, Charité-University Medicine, Berlin, Germany.
Mende S; Institute of Pathology, Charité-University Medicine, Berlin, Germany.
Seegebarth A; Institute of Pathology, Charité-University Medicine, Berlin, Germany.
Siegmund B; Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité-University Medicine, Berlin, Germany.
Hennig S; HS Diagnomics GmbH, Berlin, Germany.
Todorova K; Center for Tumor Medicine, Charité-University Medicine, Berlin, Germany.
Rosenwald A; Institute of Pathology, University of Würzburg, and Comprehensive Cancer Center Mainfranken (CCCMF), Würzburg, Germany.
Daum S; Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité-University Medicine, Berlin, Germany.
Hummel M; Institute of Pathology, Charité-University Medicine, Berlin, Germany.
Schumann M; Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité-University Medicine, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.; Berlin-Brandenburg School for Regenerative Therapies, Berlin, Germany.
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Źródło :
Gut [Gut] 2018 Apr; Vol. 67 (4), pp. 644-653. Date of Electronic Publication: 2017 Feb 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Celiac Disease/*diagnosis
Celiac Disease/*metabolism
Genes, T-Cell Receptor beta/*genetics
T-Lymphocytes/*metabolism
Adult ; Aged ; Aged, 80 and over ; Biomarkers/metabolism ; Case-Control Studies ; Celiac Disease/classification ; Celiac Disease/genetics ; Diagnosis, Differential ; Diet, Gluten-Free/methods ; Duodenum/pathology ; Female ; Genes, T-Cell Receptor beta/immunology ; Humans ; Immunosuppressive Agents/therapeutic use ; Intestinal Mucosa/pathology ; Intestine, Small/pathology ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Evidence for a role of RUNX1 as recombinase cofactor for TCRβ rearrangements and pathological deletions in ETV6-RUNX1 ALL.
Autorzy :
Seitz, V.
Kleo, K.
Dröge, A.
Schaper, S.
Elezkurtaj, S.
Bedjaoui, N.
Dimitrova, L.
Sommerfeld, A.
Berg, E.
von der Wall, E.
Müller, U.
Joosten, M.
Lenze, D.
Heimesaat, M. M.
Baldus, C.
Zinser, C.
Cieslak, A.
Macintyre, E.
Stocking, C.
Hennig, S.
Pokaż więcej
Źródło :
Scientific Reports. 6/22/2020, Vol. 10 Issue 1, p1-16. 16p.
Czasopismo naukowe
Tytuł :
Clonal T cell receptor gene rearrangements in coeliac disease: implications for diagnosing refractory coeliac disease.
Autorzy :
Hussein S; Department of Pathology and Cell Biology, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Gindin T; Department of Pathology and Cell Biology, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Lagana SM; Department of Pathology and Cell Biology, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Arguelles-Grande C; Department of Medicine, Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Krishnareddy S; Department of Medicine, Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Alobeid B; Department of Pathology and Cell Biology, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Lewis SK; Department of Medicine, Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Mansukhani MM; Department of Pathology and Cell Biology, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Green PHR; Department of Medicine, Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
Bhagat G; Department of Pathology and Cell Biology, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.; Department of Medicine, Celiac Disease Center, New York Presbyterian Hospital/Columbia University Medical Center, New York, USA.
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2018 Sep; Vol. 71 (9), pp. 825-831. Date of Electronic Publication: 2018 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Rearrangement*
Genes, T-Cell Receptor*
Celiac Disease/*genetics
Intestine, Small/*immunology
Intraepithelial Lymphocytes/*immunology
Adult ; Aged ; Aged, 80 and over ; Biopsy ; Celiac Disease/diagnosis ; Celiac Disease/diet therapy ; Celiac Disease/immunology ; Clone Cells ; Diet, Gluten-Free ; Female ; Flow Cytometry ; Genetic Predisposition to Disease ; Humans ; Immunophenotyping/methods ; Intestine, Small/pathology ; Intraepithelial Lymphocytes/pathology ; Male ; Middle Aged ; Phenotype ; Polymerase Chain Reaction ; Predictive Value of Tests ; Young Adult
Czasopismo naukowe
Tytuł :
Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A.
Autorzy :
Merleev AA; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.
Marusina AI; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.
Ma C; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.
Elder JT; Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Tsoi LC; Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Raychaudhuri SP; Department of Internal Medicine, Division of Rheumatology, Allergy & Clinical immunology, UCD School of Medicine, Sacramento, California, USA.; VA Medical Center Sacramento, Division of Rheumatology & Immunology, Sacramento, California, USA.
Weidinger S; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany.
Wang EA; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.
Adamopoulos IE; Department of Internal Medicine, Division of Rheumatology, Allergy & Clinical immunology, UCD School of Medicine, Sacramento, California, USA.
Luxardi G; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.
Gudjonsson JE; Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Shimoda M; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.
Maverakis E; Department of Dermatology, School of Medicine, UCD, Sacramento, California, USA.; Department of Medical Microbiology and Immunology, School of Medicine, UCD, California, USA.
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Źródło :
JCI insight [JCI Insight] 2018 Jul 12; Vol. 3 (13). Date of Electronic Publication: 2018 Jul 12.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta/*genetics
Interleukin-17/*genetics
Psoriasis/*genetics
Sequence Analysis, RNA/*methods
Animals ; Autoimmune Diseases/genetics ; Cytokines/metabolism ; Gene Expression Regulation ; Genes, T-Cell Receptor beta/immunology ; Humans ; Interleukin-17/immunology ; Mice ; Psoriasis/immunology ; Skin ; Transcription Factors
Czasopismo naukowe
Tytuł :
Distinct immune characteristics distinguish hereditary and idiopathic chronic pancreatitis.
Autorzy :
Lee B; Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical School, Stanford, California, USA.
Adamska JZ; Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical School, Stanford, California, USA.
Namkoong H; Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical School, Stanford, California, USA.
Bellin MD; Schulze Diabetes Institute, Department of Surgery, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.; Department of Pediatrics, University of Minnesota Medical Center and Masonic Children's Hospital, Minneapolis, Minnesota, USA.
Wilhelm J; Schulze Diabetes Institute, Department of Surgery, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.
Szot GL; Division of Transplantation, Department of Surgery, UCSF, San Francisco, California, USA.
Louis DM; Department of Microbiology and Immunology.
Davis MM; Department of Microbiology and Immunology.; Institute for Immunity, Transplantation and Infection, and.; Howard Hughes Medical Institute (HHMI), Stanford University Medical School, Stanford, California, USA.
Pandol SJ; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Habtezion A; Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical School, Stanford, California, USA.; Institute for Immunity, Transplantation and Infection, and.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 May 01; Vol. 130 (5), pp. 2705-2711.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Pancreatitis, Chronic/*genetics
Pancreatitis, Chronic/*immunology
Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Female ; Genes, T-Cell Receptor beta ; Humans ; Macrophages/immunology ; Macrophages/pathology ; Male ; Pancreas/immunology ; Pancreas/pathology ; Pancreatitis, Chronic/pathology ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/pathology
SCR Disease Name :
Hereditary pancreatitis
Czasopismo naukowe
Tytuł :
Assessment of Thymic Output Dynamics After in utero Infection of Mice With Coxsackievirus B4.
Autorzy :
Halouani A; Laboratoire des Maladies Transmissibles et Substances Biologiquement Actives, Faculté de Pharmacie de Monastir, Université de Monastir, Monastir, Tunisia.; Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis, Tunisia.; GIGA-I3 Neuroimmunoendocrinology, GIGA Research Institute, University of Liège, Liège, Belgium.
Jmii H; Laboratoire des Maladies Transmissibles et Substances Biologiquement Actives, Faculté de Pharmacie de Monastir, Université de Monastir, Monastir, Tunisia.; Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Bodart G; GIGA-I3 Neuroimmunoendocrinology, GIGA Research Institute, University of Liège, Liège, Belgium.
Michaux H; GIGA-I3 Neuroimmunoendocrinology, GIGA Research Institute, University of Liège, Liège, Belgium.
Renard C; GIGA-I3 Neuroimmunoendocrinology, GIGA Research Institute, University of Liège, Liège, Belgium.
Martens H; GIGA-I3 Neuroimmunoendocrinology, GIGA Research Institute, University of Liège, Liège, Belgium.
Aouni M; Laboratoire des Maladies Transmissibles et Substances Biologiquement Actives, Faculté de Pharmacie de Monastir, Université de Monastir, Monastir, Tunisia.
Hober D; Université de Lille, CHU de Lille, Laboratoire de Virologie, Lille, France.
Geenen V; GIGA-I3 Neuroimmunoendocrinology, GIGA Research Institute, University of Liège, Liège, Belgium.
Jaïdane H; Laboratoire des Maladies Transmissibles et Substances Biologiquement Actives, Faculté de Pharmacie de Monastir, Université de Monastir, Monastir, Tunisia.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Apr 02; Vol. 11, pp. 481. Date of Electronic Publication: 2020 Apr 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoimmune Diseases/*immunology
Coxsackievirus Infections/*immunology
Enterovirus/*physiology
Thymus Gland/*physiology
Uterus/*immunology
Animals ; Autoimmunity ; Cell Differentiation ; Cell Proliferation ; Coxsackievirus Infections/transmission ; Down-Regulation ; Enterovirus/pathogenicity ; Female ; Genes, T-Cell Receptor beta/genetics ; Infectious Disease Transmission, Vertical ; Male ; Mice ; Receptor Protein-Tyrosine Kinases/genetics ; Receptor Protein-Tyrosine Kinases/metabolism ; Thymus Gland/virology ; Uterus/virology ; Viral Load
Czasopismo naukowe
Tytuł :
TCR Vβ Usage of Peripheral Blood and Liver Infiltrating Lymphocytes in Patients with Chronic Hepatitis B.
Autorzy :
Zhou J; Affiliated Hospital of Jining Medical University, China. Clinical Laboratory.
Kong C; Affiliated Hospital of Jining Medical University, China. Nursing Department.
Ban B; Affiliated Hospital of Jining Medical University, China. Endocrinology Department.
Dong H; Affiliated Hospital of Jining Medical University, China. Clinical Laboratory.
Jin C; Affiliated Hospital of Jining Medical University, China. Clinical Laboratory.
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Źródło :
Annals of hepatology [Ann Hepatol] 2018 Mar 01; Vol. 17 (2), pp. 214-222.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor beta*
Hepatitis B, Chronic/*genetics
Hepatitis B, Chronic/*immunology
Immunoglobulin Variable Region/*genetics
Liver/*immunology
Lymphocytes/*immunology
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Adult ; Case-Control Studies ; Complementarity Determining Regions/genetics ; Complementarity Determining Regions/immunology ; Female ; HLA-DR Serological Subtypes/genetics ; HLA-DR Serological Subtypes/immunology ; Hepatitis B, Chronic/diagnosis ; Hepatitis B, Chronic/virology ; Host-Pathogen Interactions ; Humans ; Immunoglobulin Variable Region/immunology ; Liver/virology ; Lymphocytes/virology ; Male ; Middle Aged ; Receptors, Antigen, T-Cell, alpha-beta/immunology
Czasopismo naukowe
Tytuł :
The deterministic role of 5-mers in microRNA-gene targeting.
Autorzy :
Hart M; a Institute of Human Genetics, Saarland University , Homburg , Germany.
Kern F; b Chair for Clinical Bioinformatics, Saarland University , Saarbrücken , Germany.
Backes C; b Chair for Clinical Bioinformatics, Saarland University , Saarbrücken , Germany.
Rheinheimer S; a Institute of Human Genetics, Saarland University , Homburg , Germany.
Fehlmann T; b Chair for Clinical Bioinformatics, Saarland University , Saarbrücken , Germany.
Keller A; b Chair for Clinical Bioinformatics, Saarland University , Saarbrücken , Germany.
Meese E; a Institute of Human Genetics, Saarland University , Homburg , Germany.
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Źródło :
RNA biology [RNA Biol] 2018; Vol. 15 (6), pp. 819-825. Date of Electronic Publication: 2018 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
3' Untranslated Regions*
Genes, T-Cell Receptor alpha*
MicroRNAs*/genetics
MicroRNAs*/metabolism
Computer Simulation ; HEK293 Cells ; Humans
Czasopismo naukowe
Tytuł :
T cell receptor (TCR) genes in circulating cells of patients with systemic lupus erythematosus and their healthy relatives
Autorzy :
Jakez-Ocampo J; Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
Paulín-Vera CM; Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
Rivadeneyra-Espinoza L; Laboratorios Clínicos de Puebla, Puebla, Pue. México.
Gómez-Martín D; Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
Carrillo-Maravilla E; Departamento de Medicina Interna, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
Lima G; Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
Vargas-Rojas MI; Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
Pérez-Romano B; Laboratorios Clínicos de Puebla, Puebla, Pue. México.
Calva-Cevenini G; Laboratorios Clínicos de Puebla, Puebla, Pue. México.
García-Carrasco M; Escuela de Medicina, Benemérita Universidad Autónoma de Puebla, Puebla, Pue. México.
Ruiz-Argüelles A; Laboratorios Clínicos de Puebla, Puebla, Pue. México.
Llorente L; Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México. México.
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Transliterated Title :
Genes del receptor variable beta de células T en células circulantes de pacientes con lupus eritematoso generalizado y sus familiares sanos.
Źródło :
Gaceta medica de Mexico [Gac Med Mex] 2018; Vol. 154 (1), pp. 74-79.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor beta*/genetics
T-Lymphocytes*
Lupus Erythematosus, Systemic/*blood
Case-Control Studies ; Female ; Humans ; Lupus Erythematosus, Systemic/genetics ; Male
Czasopismo naukowe
Tytuł :
High-throughput sequencing of the T cell receptor β gene identifies aggressive early-stage mycosis fungoides.
Autorzy :
de Masson A; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
O'Malley JT; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Elco CP; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Garcia SS; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Divito SJ; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Lowry EL; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Tawa M; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Fisher DC; Center for Hematologic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Devlin PM; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Teague JE; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Leboeuf NR; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA.
Kirsch IR; Adaptive Biotechnologies, Seattle, WA 98102, USA.
Robins H; Adaptive Biotechnologies, Seattle, WA 98102, USA.
Clark RA; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA. .
Kupper TS; Department of Dermatology, Brigham and Women's Hospital, and the Center for Cutaneous Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA 02115, USA. .
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Źródło :
Science translational medicine [Sci Transl Med] 2018 May 09; Vol. 10 (440).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
High-Throughput Nucleotide Sequencing/*methods
Mycosis Fungoides/*genetics
Mycosis Fungoides/*immunology
Skin Neoplasms/*genetics
Skin Neoplasms/*immunology
Cellular Microenvironment ; Clone Cells ; Exome/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphoma, T-Cell, Cutaneous/genetics ; Lymphoma, T-Cell, Cutaneous/immunology ; Lymphoma, T-Cell, Cutaneous/pathology ; Male ; Middle Aged ; Multivariate Analysis ; Mycosis Fungoides/pathology ; Prognosis ; Progression-Free Survival ; Skin/pathology ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Adjustments of γδ T Cells in the Lung of Schistosoma japonicum -Infected C56BL/6 Mice.
Autorzy :
Cha H; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xie H; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jin C; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Feng Y; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xie S; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xie A; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yang Q; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Qi Y; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Qiu H; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wu Q; Department of Immunology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Yin Z; Biomedical Translational Research Institute, School of Pharmacy, Jinan University, Guangzhou, China.
Mu J; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Huang J; Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Sino-French Hoffmann Institute, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Jun 04; Vol. 11, pp. 1045. Date of Electronic Publication: 2020 Jun 04 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intraepithelial Lymphocytes/*immunology
Intraepithelial Lymphocytes/*parasitology
Lung/*immunology
Lung/*parasitology
Schistosomiasis japonica/*immunology
Animals ; B-Lymphocytes/immunology ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Genes, T-Cell Receptor delta ; Immunity, Innate ; Immunophenotyping ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Antigen, T-Cell, gamma-delta/deficiency ; Receptors, Antigen, T-Cell, gamma-delta/genetics ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Schistosoma japonicum/immunology ; Schistosoma japonicum/pathogenicity ; Schistosomiasis japonica/parasitology ; Schistosomiasis japonica/pathology
Czasopismo naukowe
Tytuł :
Maternal T Cells in the Human Placental Villi Support an Allograft Response during Noninfectious Villitis.
Autorzy :
Enninga EAL; Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905; .
Raber P; Adaptive Biotechnologies, Seattle, WA 98102.
Quinton RA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905.
Ruano R; Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905.
Ikumi N; Division of Immunology, Institute of Infectious Disease and Molecular Medicine, Department of Pathology, University of Cape Town, Cape Town, South Africa 7791.
Gray CM; Division of Immunology, Institute of Infectious Disease and Molecular Medicine, Department of Pathology, University of Cape Town, Cape Town, South Africa 7791.
Johnson EL; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322.
Chakraborty R; Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905.; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905.; Department of Immunology, Mayo Clinic, Rochester, MN 55905; and.
Kerr SE; Hospital Pathology Associates, Minneapolis, MN 55407.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Jun 01; Vol. 204 (11), pp. 2931-2939. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Chorionic Villi/*immunology
Genes, T-Cell Receptor beta/*genetics
Graft Rejection/*immunology
Inflammation/*immunology
Placenta Diseases/*immunology
Pregnancy/*immunology
T-Lymphocytes/*immunology
Adult ; Allografts/immunology ; Antigens, Viral/immunology ; Cell Movement ; Cohort Studies ; Epitopes, T-Lymphocyte/immunology ; Female ; Fetus ; HLA Antigens/immunology ; Humans ; Young Adult
Czasopismo naukowe
Tytuł :
Tumoral PD-1hiCD8+ T cells are partially exhausted and predict favorable outcome in triple-negative breast cancer.
Autorzy :
Guo L; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
Cao C; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
Goswami S; The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, P.R. China.
Huang X; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
Ma L; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
Guo Y; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, U.S.A.
Yang B; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
Li T; The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, P.R. China.
Chi Y; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
Zhang X; The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, P.R. China.
Wu J; Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.; Collaborative Innovation Center for Cancer Medicine, Shanghai 200032, P.R. China.
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Źródło :
Clinical science (London, England : 1979) [Clin Sci (Lond)] 2020 Apr 17; Vol. 134 (7), pp. 711-726.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*immunology
CD8-Positive T-Lymphocytes/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Programmed Cell Death 1 Receptor/*immunology
Triple Negative Breast Neoplasms/*immunology
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/pathology ; Disease-Free Survival ; Female ; Gene Expression Regulation, Neoplastic ; Genes, T-Cell Receptor ; Humans ; Immunologic Memory ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Middle Aged ; Phenotype ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Prospective Studies ; Risk Factors ; Time Factors ; Transcriptome ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/mortality ; Triple Negative Breast Neoplasms/surgery ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Identification of genes of prognostic value in the ccRCC microenvironment from TCGA database.
Autorzy :
Wan B; Department of Urology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, Hainan, China.
Liu B; Laboratory of Developmental Cell Biology and Disease, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Huang Y; Department of Neurology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, Hainan, China.
Lv C; Department of Urology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, Hainan, China.
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Źródło :
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2020 Apr; Vol. 8 (4), pp. e1159. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*genetics
Carcinoma, Renal Cell/*genetics
Kidney Neoplasms/*genetics
Tumor Microenvironment/*genetics
Carcinoma, Renal Cell/pathology ; Cytokines/genetics ; Cytokines/metabolism ; Databases, Genetic ; Genes, T-Cell Receptor ; Humans ; Kidney Neoplasms/pathology ; Protein Interaction Maps ; Transcriptome
Czasopismo naukowe
Tytuł :
A Subset of Human Autoreactive CD1c-Restricted T Cells Preferentially Expresses TRBV4-1 TCRs.
Autorzy :
Guo T; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and.
Koo MY; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and.
Kagoya Y; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.
Anczurowski M; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and.
Wang CH; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and.
Saso K; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.
Butler MO; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and.; Department of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Hirano N; Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada; .; Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2018 Jan 15; Vol. 200 (2), pp. 500-511. Date of Electronic Publication: 2017 Dec 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autoimmunity*
Gene Expression*
Genes, T-Cell Receptor beta*
Antigens, CD1/*immunology
Antigens, CD1/*metabolism
T-Lymphocyte Subsets/*immunology
T-Lymphocyte Subsets/*metabolism
Antigen Presentation/immunology ; Antigen-Presenting Cells/immunology ; Antigen-Presenting Cells/metabolism ; Arginine/genetics ; Biomarkers ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cell Line ; Clonal Evolution/genetics ; Clonal Evolution/immunology ; Codon ; Complementarity Determining Regions/genetics ; Humans ; Immunophenotyping ; Lymphocyte Activation ; Phenotype ; Tyrosine/genetics
Czasopismo naukowe
Tytuł :
Inverse correlation of Vδ2 T-cell recovery with EBV reactivation after haematopoietic stem cell transplantation.
Autorzy :
Liu J; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Bian Z; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Wang X; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Xu LP; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Fu Q; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Wang C; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Chang YJ; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Wang Y; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Zhang XH; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Jiang Z; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Huang XJ; Peking University People's Hospital, Peking University Institute of Hematology, Beijing Key laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
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Źródło :
British journal of haematology [Br J Haematol] 2018 Jan; Vol. 180 (2), pp. 276-285. Date of Electronic Publication: 2017 Dec 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor delta*
Hematopoietic Stem Cell Transplantation*/adverse effects
Virus Activation*
Epstein-Barr Virus Infections/*etiology
Herpesvirus 4, Human/*physiology
T-Lymphocytes/*metabolism
Adolescent ; Adult ; Apoptosis/genetics ; Apoptosis/immunology ; Cytotoxicity, Immunologic ; Epstein-Barr Virus Infections/diagnosis ; Female ; Graft vs Host Disease/etiology ; Graft vs Host Disease/prevention & control ; HLA Antigens/genetics ; HLA Antigens/immunology ; Haplotypes ; Humans ; Incidence ; Lymphocyte Activation/immunology ; Male ; Middle Aged ; T-Lymphocytes/immunology ; Transplantation, Homologous ; Young Adult
Czasopismo naukowe
Tytuł :
PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation.
Autorzy :
Shimizu K; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
Sugiura D; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
Okazaki IM; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
Maruhashi T; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
Takegami Y; K.K. DNAFORM, Yokohama, Kanagawa 230-0046, Japan.
Cheng C; K.K. DNAFORM, Yokohama, Kanagawa 230-0046, Japan.
Ozaki S; K.K. DNAFORM, Yokohama, Kanagawa 230-0046, Japan.
Okazaki T; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Mar 05; Vol. 77 (5), pp. 937-950.e6. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
Transcriptome*
Lymphocytes, Tumor-Infiltrating/*metabolism
Neoplasms/*metabolism
Programmed Cell Death 1 Receptor/*metabolism
T-Lymphocytes/*metabolism
Animals ; Apoptosis ; Binding Sites ; Cell Proliferation ; Coculture Techniques ; CpG Islands ; Cytokines/genetics ; Cytokines/metabolism ; Gene Expression Regulation, Neoplastic ; Genes, T-Cell Receptor ; HEK293 Cells ; Humans ; Jurkat Cells ; Lymphocytes, Tumor-Infiltrating/immunology ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Neoplasms/genetics ; Neoplasms/immunology ; Neoplasms/pathology ; Programmed Cell Death 1 Receptor/deficiency ; Programmed Cell Death 1 Receptor/genetics ; Promoter Regions, Genetic ; Signal Transduction ; T-Lymphocytes/immunology ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł :
Alterations in T and B Cell Receptor Repertoires Patterns in Patients With IL10 Signaling Defects and History of Infantile-Onset IBD.
Autorzy :
Werner L; Pediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lee YN; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Pediatric Department A, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Immunology Service, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.
Rechavi E; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Pediatric Department A, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Immunology Service, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.
Lev A; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Pediatric Department A, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Immunology Service, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.
Yerushalmi B; Pediatric Gastroenterology Unit, Soroka University Medical Center, Ben Gurion University of the Negev, Be'er Sheva, Israel.
Ling G; Pediatric Gastroenterology Unit, Soroka University Medical Center, Ben Gurion University of the Negev, Be'er Sheva, Israel.
Shah N; Department of Gastroenterology, Great Ormond Street Hospital, London, United Kingdom.
Uhlig HH; Translational Gastroenterology Unit, Nuffield Department of Experimental Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.; Department of Pediatrics, University of Oxford, Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
Weiss B; Pediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Somech R; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Pediatric Department A, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Immunology Service, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.
Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, United States.; Harvard Medical School, Boston, MA, United States.
Shouval DS; Pediatric Gastroenterology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Centre, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Feb 06; Vol. 11, pp. 109. Date of Electronic Publication: 2020 Feb 06 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammatory Bowel Diseases/*immunology
Interleukin-10/*genetics
Receptors, Antigen, B-Cell/*genetics
Receptors, Antigen, T-Cell/*genetics
Receptors, Interleukin-10/*genetics
Adaptive Immunity ; B-Lymphocytes ; Child, Preschool ; Female ; Genes, T-Cell Receptor beta ; High-Throughput Nucleotide Sequencing ; Humans ; Infant ; Infant, Newborn ; Interleukin-10/deficiency ; Lymphocytes/immunology ; Male ; Mutation ; Receptors, Interleukin-10/deficiency ; Signal Transduction ; T-Lymphocytes
Czasopismo naukowe
Tytuł :
Simultaneous Deletion of Endogenous TCRαβ for TCR Gene Therapy Creates an Improved and Safe Cellular Therapeutic.
Autorzy :
Morton LT; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: l.t..
Reijmers RM; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Wouters AK; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Kweekel C; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Remst DFG; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Pothast CR; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Falkenburg JHF; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.
Heemskerk MHM; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: .
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 Jan 08; Vol. 28 (1), pp. 64-74. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CRISPR-Cas Systems*
Adoptive Transfer/*methods
Gene Editing/*methods
Genetic Therapy/*methods
Multiple Myeloma/*therapy
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Adoptive Transfer/adverse effects ; Animals ; Antigens, Neoplasm/immunology ; CD8-Positive T-Lymphocytes ; Female ; Genes, T-Cell Receptor ; Genetic Therapy/adverse effects ; Healthy Volunteers ; Humans ; K562 Cells ; Male ; Mice ; Mice, Inbred NOD ; Multiple Myeloma/pathology ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Transduction, Genetic ; Treatment Outcome ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Characterization of the diversity of T cell receptor γδ complementary determinant region 3 in human peripheral blood by Immune Repertoire Sequencing.
Autorzy :
Chen H; Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology, Beijing 100005, China.
Zou M; Department of Clinical Laboratory, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan 250012, China.
Teng D; Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology, Beijing 100005, China.
Zhang J; Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology, Beijing 100005, China. Electronic address: .
He W; Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, State Key Laboratory of Medical Molecular Biology, Beijing 100005, China. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2017 Apr; Vol. 443, pp. 9-17. Date of Electronic Publication: 2017 Jan 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor delta*
Genes, T-Cell Receptor gamma*
Complementarity Determining Regions/*genetics
Receptors, Antigen, T-Cell, gamma-delta/*genetics
Sequence Analysis, DNA/*methods
T-Lymphocytes/*immunology
Adult ; Aged ; Complementarity Determining Regions/immunology ; Female ; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor ; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor ; Genotype ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Phenotype ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
High frequency of clonal IG and T-cell receptor gene rearrangements in histiocytic and dendritic cell neoplasms.
Autorzy :
Huang W; Department of Pathology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qiu T; Department of Pathology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zeng L; Department of Pathology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zheng B; Department of Pathology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ying J; Department of Pathology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Feng X; Department of Pathology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło :
Oncotarget [Oncotarget] 2016 Nov 29; Vol. 7 (48), pp. 78355-78362.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor*
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor*
Genes, Immunoglobulin Heavy Chain*
Genes, T-Cell Receptor beta*
Genes, T-Cell Receptor gamma*
Biomarkers, Tumor/*genetics
Histiocytic Disorders, Malignant/*genetics
Histiocytosis, Langerhans-Cell/*genetics
Immunoglobulin kappa-Chains/*genetics
Adolescent ; Adult ; Aged ; Child ; Dendritic Cell Sarcoma, Follicular/genetics ; Dendritic Cell Sarcoma, Follicular/immunology ; Dendritic Cell Sarcoma, Follicular/pathology ; Dendritic Cell Sarcoma, Interdigitating/genetics ; Dendritic Cell Sarcoma, Interdigitating/immunology ; Dendritic Cell Sarcoma, Interdigitating/pathology ; Female ; Genetic Predisposition to Disease ; Histiocytic Disorders, Malignant/immunology ; Histiocytic Disorders, Malignant/pathology ; Histiocytic Sarcoma/genetics ; Histiocytic Sarcoma/immunology ; Histiocytic Sarcoma/pathology ; Histiocytosis, Langerhans-Cell/immunology ; Histiocytosis, Langerhans-Cell/pathology ; Humans ; Langerhans Cell Sarcoma/genetics ; Langerhans Cell Sarcoma/immunology ; Langerhans Cell Sarcoma/pathology ; Male ; Middle Aged ; Phenotype ; Young Adult
Czasopismo naukowe
Tytuł :
Prospects for chimeric antigen receptor (CAR) γδ T cells: A potential game changer for adoptive T cell cancer immunotherapy.
Autorzy :
Mirzaei HR; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mirzaei H; Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Lee SY; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Hadjati J; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Cancer Biology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: .
Till BG; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2016 Oct 01; Vol. 380 (2), pp. 413-423. Date of Electronic Publication: 2016 Jul 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genes, T-Cell Receptor delta*
Genes, T-Cell Receptor gamma*
Genetic Therapy/*methods
Immunotherapy, Adoptive/*methods
Lymphocytes, Tumor-Infiltrating/*transplantation
Neoplasms/*therapy
Receptors, Antigen, T-Cell, gamma-delta/*genetics
T-Lymphocytes/*transplantation
Animals ; Humans ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Phenotype ; Receptors, Antigen, T-Cell, gamma-delta/biosynthesis ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Recombinant Fusion Proteins/biosynthesis ; Recombinant Fusion Proteins/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
High-throughput single-cell sequencing of paired TCRα and TCRβ genes for the direct expression-cloning and functional analysis of murine T-cell receptors.
Autorzy :
Ludwig J; Department of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.
Huber AK; Department of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.
Bartsch I; Department of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.
Busse CE; Department of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.
Wardemann H; Department of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.
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Źródło :
European journal of immunology [Eur J Immunol] 2019 Aug; Vol. 49 (8), pp. 1269-1277. Date of Electronic Publication: 2019 May 02.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor alpha/*genetics
Genes, T-Cell Receptor beta/*genetics
High-Throughput Nucleotide Sequencing/*methods
Receptors, Antigen, T-Cell, alpha-beta/*genetics
T-Lymphocytes/*physiology
Animals ; Clone Cells ; Mice ; Phenotype ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Safety and persistence of WT1-specific T-cell receptor gene-transduced lymphocytes in patients with AML and MDS.
Autorzy :
Tawara I; Department of Hematology and Oncology and.
Kageyama S; Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan.
Miyahara Y; Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan.
Fujiwara H; Department of Hematology, Clinical Immunology and Infectious Diseases, Graduate School of Medicine, Ehime University, Ehime, Japan.
Nishida T; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Akatsuka Y; Department of Hematology, Fujita Health University School of Medicine, Aichi, Japan.
Ikeda H; Department of Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; and.
Tanimoto K; Department of Hematology, Clinical Immunology and Infectious Diseases, Graduate School of Medicine, Ehime University, Ehime, Japan.
Terakura S; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Murata M; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Inaguma Y; Department of Hematology, Fujita Health University School of Medicine, Aichi, Japan.
Masuya M; Department of Hematology and Oncology and.
Inoue N; Takara Bio Inc., Shiga, Japan.
Kidokoro T; Takara Bio Inc., Shiga, Japan.
Okamoto S; Takara Bio Inc., Shiga, Japan.
Tomura D; Takara Bio Inc., Shiga, Japan.
Chono H; Takara Bio Inc., Shiga, Japan.
Nukaya I; Takara Bio Inc., Shiga, Japan.
Mineno J; Takara Bio Inc., Shiga, Japan.
Naoe T; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Emi N; Department of Hematology, Fujita Health University School of Medicine, Aichi, Japan.
Yasukawa M; Department of Hematology, Clinical Immunology and Infectious Diseases, Graduate School of Medicine, Ehime University, Ehime, Japan.
Katayama N; Department of Hematology and Oncology and.
Shiku H; Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan.
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Źródło :
Blood [Blood] 2017 Nov 02; Vol. 130 (18), pp. 1985-1994. Date of Electronic Publication: 2017 Aug 31.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Transduction, Genetic*
Leukemia, Myeloid, Acute/*therapy
Myelodysplastic Syndromes/*therapy
T-Lymphocytes/*metabolism
WT1 Proteins/*genetics
Adoptive Transfer ; Aged ; Bone Marrow/pathology ; Female ; Humans ; Kinetics ; Leukemia, Myeloid, Acute/genetics ; Male ; Middle Aged ; Myelodysplastic Syndromes/genetics ; Peptides/pharmacology
Czasopismo naukowe
Tytuł :
Composition and Variation Analysis of the T Cell Receptor β-Chain Complementarity Determining Region 3 Repertoire in Neonatal Sepsis.
Autorzy :
Sun J; Department of Clinical Immunology, Children's Hospital of Fudan University, Shanghai, China.
Sun B; Department of Clinical Immunology, Children's Hospital of Fudan University, Shanghai, China.
Gao Y; Department of Ultrasound, Children's Hospital of Fudan University, Shanghai, China.
He F; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Yang L; Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
Wang M; Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
Zhou W; Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
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Źródło :
Scandinavian journal of immunology [Scand J Immunol] 2017 Nov; Vol. 86 (5), pp. 418-423. Date of Electronic Publication: 2017 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor beta*
Complementarity Determining Regions/*genetics
Neonatal Sepsis/*genetics
Neonatal Sepsis/*immunology
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Case-Control Studies ; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor ; Genetic Predisposition to Disease ; Genetic Variation ; Humans ; Infant, Newborn
Czasopismo naukowe
Tytuł :
Study of the T-cell receptor repertoire by CDR3 spectratyping.
Autorzy :
Fozza C; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy. Electronic address: .
Barraqueddu F; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
Corda G; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
Contini S; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
Virdis P; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
Dore F; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
Bonfigli S; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
Longinotti M; Hematology, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 12, 07100 Sassari, Italy.
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Źródło :
Journal of immunological methods [J Immunol Methods] 2017 Jan; Vol. 440, pp. 1-11. Date of Electronic Publication: 2016 Nov 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genes, T-Cell Receptor*
Immunologic Techniques*
Communicable Diseases/*immunology
Complementarity Determining Regions/*immunology
Hematologic Neoplasms/*immunology
Immune System Diseases/*immunology
Receptors, Antigen, T-Cell/*immunology
T-Lymphocytes/*immunology
Animals ; Cell Separation ; Communicable Diseases/genetics ; Complementarity Determining Regions/genetics ; Electrophoresis, Capillary ; Hematologic Neoplasms/genetics ; Humans ; Immune System Diseases/genetics ; RNA/genetics ; RNA/isolation & purification ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
A new transcript in the TCRB locus unveils the human ortholog of the mouse pre-Dß1 promoter.
Autorzy :
Lethé B; Ludwig Institute for Cancer Research, Brussels, Belgium.; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Snauwaert S; Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium.
Bricard O; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Schröder D; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Gomard T; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Hames G; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Muller C; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Lurquin C; Ludwig Institute for Cancer Research, Brussels, Belgium.; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Gauthy E; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Essaghir A; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Vandekerckhove B; Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium.
Coulie PG; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
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Źródło :
Immunity, inflammation and disease [Immun Inflamm Dis] 2017 Sep; Vol. 5 (3), pp. 346-354. Date of Electronic Publication: 2017 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Genetic Loci*
Promoter Regions, Genetic*
Transcription, Genetic*
RNA, Messenger/*genetics
Animals ; Humans ; Mice ; RNA, Messenger/biosynthesis
Czasopismo naukowe
Tytuł :
Primary cutaneous γδ T-cell lymphoma with unusual immunophenotype: A case report and review of published work.
Autorzy :
Kamijo H; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Miyagaki T; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.; Department of Dermatology, St Marianna University School of Medicine, Kawasaki, Japan.
Norimatsu Y; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Awaji K; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Oka T; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Suga H; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Sugaya M; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.; Department of Dermatology, International University of Health and Welfare, Chiba, Japan.
Sato S; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
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Źródło :
The Journal of dermatology [J Dermatol] 2020 Mar; Vol. 47 (3), pp. 300-305. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
CD3 Complex/*metabolism
CD5 Antigens/*metabolism
Lymphoma, T-Cell, Cutaneous/*pathology
Receptors, Antigen, T-Cell, gamma-delta/*metabolism
Skin Neoplasms/*pathology
T-Lymphocytes/*metabolism
Aged ; CD8 Antigens/metabolism ; Genes, T-Cell Receptor gamma/genetics ; Humans ; Immunohistochemistry ; Immunophenotyping ; Lymphoma, T-Cell, Cutaneous/genetics ; Male ; Skin Neoplasms/genetics
Czasopismo naukowe
Tytuł :
The aorta can act as a site of naïve CD4+ T-cell priming.
Autorzy :
MacRitchie N; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Grassia G; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Noonan J; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Cole JE; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
Hughes CE; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Schroeder J; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Benson RA; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Cochain C; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.
Zernecke A; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.
Guzik TJ; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.; Department of Internal Medicine, Jagiellonian University, Collegium Medicum, Kraków, Poland.
Garside P; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.
Monaco C; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.
Maffia P; Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK.; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.; Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
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Źródło :
Cardiovascular research [Cardiovasc Res] 2020 Feb 01; Vol. 116 (2), pp. 306-316.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptive Immunity*
Cell Proliferation*
Lymphocyte Activation*
Aorta/*immunology
Aortic Diseases/*immunology
Atherosclerosis/*immunology
T-Lymphocytes, Regulatory/*immunology
Th1 Cells/*immunology
Animals ; Aorta/metabolism ; Aorta/pathology ; Aortic Diseases/genetics ; Aortic Diseases/metabolism ; Aortic Diseases/pathology ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cells, Cultured ; Cytokines/metabolism ; Disease Models, Animal ; Disease Progression ; Genes, T-Cell Receptor ; Kinetics ; Membrane Glycoproteins/metabolism ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; Phenotype ; Plaque, Atherosclerotic ; T-Lymphocytes, Regulatory/metabolism ; Th1 Cells/metabolism
Czasopismo naukowe
Tytuł :
Genomic organization of the chicken TCRβ locus originated by duplication of a Vβ segment combined with a trypsinogen gene.
Autorzy :
Zhang T; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, PR China.
Liu G; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, PR China.
Wei Z; College of Animal Science and Technology, Henan University of Science and Technology, 263 Kaiyuan Road, Luoyang City, Henan Province 471023, PR China.
Wang Y; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, PR China.
Kang L; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, PR China.
Jiang Y; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, PR China. Electronic address: .
Sun Y; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian City, Shandong Province 271018, PR China. Electronic address: .
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Źródło :
Veterinary immunology and immunopathology [Vet Immunol Immunopathol] 2020 Jan; Vol. 219, pp. 109974. Date of Electronic Publication: 2019 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Loci*
Chickens/*genetics
Genes, T-Cell Receptor beta/*genetics
Trypsinogen/*genetics
Animals ; Ducks/genetics ; Genome ; Phylogeny
Czasopismo naukowe
Tytuł :
Primary central nervous system ALK-positive anaplastic large cell lymphoma with CD56 abnormally expression in a Chinese child: Challenge in diagnostic practice.
Autorzy :
Liu Q; Department of Pathology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.; Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Chen X; Department of Pathology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Li G; Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Ye Y; Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Liu W; Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Zhao S; Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Zhang W; Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
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Źródło :
International journal of immunopathology and pharmacology [Int J Immunopathol Pharmacol] 2020 Jan-Dec; Vol. 34, pp. 2058738420941756.
Typ publikacji :
Case Reports
MeSH Terms :
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/genetics
Anaplastic Lymphoma Kinase/*genetics
Brain Neoplasms/*genetics
Brain Neoplasms/*immunology
CD56 Antigen/*analysis
Lymphoma, Large-Cell, Anaplastic/*genetics
Lymphoma, Large-Cell, Anaplastic/*immunology
Child ; Fatal Outcome ; Gene Rearrangement ; Genes, T-Cell Receptor gamma ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Ki-1 Antigen/analysis ; Male ; Translocation, Genetic
Raport
Tytuł :
qPCR Applications for the Determination of the Biological Age.
Autorzy :
Castagnetta M; Ente Ospedaliero Ospedali Galliera, Genoa, Italy. .
Pfeffer U; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Chiesa A; Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
Gennaro E; IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Cecconi M; IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Coviello D; IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Sacchi N; Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2065, pp. 191-197.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*genetics
Forensic Genetics/*methods
Real-Time Polymerase Chain Reaction/*methods
DNA/genetics ; DNA/isolation & purification ; Gene Rearrangement, T-Lymphocyte ; Genes, T-Cell Receptor/genetics ; Humans ; Quality Control ; Reproducibility of Results ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Lichenoid dermatitis from immune checkpoint inhibitor therapy: An immune‐related adverse event with mycosis‐fungoides‐like morphologic and molecular features.
Autorzy :
Tetzlaff, Michael T. (AUTHOR)
Tang, Sherry (AUTHOR)
Duke, Taylor (AUTHOR)
Grabell, Daniel A. (AUTHOR)
Cabanillas, Maria E. (AUTHOR)
Zuo, Zhuang (AUTHOR)
Yao, James C. (AUTHOR)
Nagarajan, Priyadharsini (AUTHOR)
Aung, Phyu P. (AUTHOR)
Torres‐Cabala, Carlos A. (AUTHOR)
Duvic, Madeleine (AUTHOR)
Prieto, Victor G. (AUTHOR)
Huen, Auris (AUTHOR)
Curry, Jonathan L. (AUTHOR)
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Źródło :
Journal of Cutaneous Pathology. Nov2019, Vol. 46 Issue 11, p872-877. 6p. 4 Diagrams.
Czasopismo naukowe
Tytuł :
Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Autorzy :
Bethune MT; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Gee MH; Program in Immunology, Stanford University School of Medicine, Stanford, United States.
Bunse M; Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Lee MS; Department of Immunobiology, University of Arizona, Tucson, United States.; The BIO5 Institute, University of Arizona, Tucson, United States.
Gschweng EH; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, United States.
Pagadala MS; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Zhou J; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States.
Cheng D; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, United States.
Heath JR; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States.
Kohn DB; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, United States.
Kuhns MS; Department of Immunobiology, University of Arizona, Tucson, United States.; The BIO5 Institute, University of Arizona, Tucson, United States.
Uckert W; Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Institute of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
Baltimore D; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
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Źródło :
ELife [Elife] 2016 Nov 08; Vol. 5. Date of Electronic Publication: 2016 Nov 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor*
Genetic Therapy/*adverse effects
Genetic Therapy/*methods
Receptors, Antigen, T-Cell/*genetics
Receptors, Antigen, T-Cell/*metabolism
Recombinant Proteins/*genetics
Recombinant Proteins/*metabolism
Animals ; Disease Models, Animal ; Graft vs Host Disease ; Mice ; Protein Domains ; Recombination, Genetic
Czasopismo naukowe
Tytuł :
The four TCR genes of teleost fish: the cDNA and genomic DNA analysis of Japanese flounder (Paralichthys olivaceus) TCR alpha-, beta-, gamma-, and delta-chains.
Autorzy :
Nam BH; Department of Aquatic Biosciences, Tokyo University of Fisheries, Minato, Tokyo, Japan.
Hirono I
Aoki T
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2003 Mar 15; Vol. 170 (6), pp. 3081-90.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Genome*
Sequence Analysis, DNA*
DNA, Complementary/*analysis
Flounder/*genetics
Flounder/*immunology
Amino Acid Sequence ; Animals ; Complementarity Determining Regions/analysis ; Complementarity Determining Regions/genetics ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Genes, T-Cell Receptor delta ; Genes, T-Cell Receptor gamma ; Genetic Markers ; Humans ; Molecular Sequence Data ; Phylogeny ; Protein Structure, Tertiary/genetics ; Receptors, Antigen, T-Cell, alpha-beta/analysis ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, gamma-delta/analysis ; Receptors, Antigen, T-Cell, gamma-delta/genetics ; Sequence Analysis, Protein ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Conserved T cell receptor alpha-chain induces insulin autoantibodies.
Autorzy :
Kobayashi M; Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Aurora, CO 80045, USA.
Jasinski J
Liu E
Li M
Miao D
Zhang L
Yu L
Nakayama M
Eisenbarth GS
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2008 Jul 22; Vol. 105 (29), pp. 10090-4. Date of Electronic Publication: 2008 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor alpha*
Autoantibodies/*biosynthesis
Insulin/*immunology
Insulin Antibodies/*biosynthesis
Adoptive Transfer ; Animals ; Base Sequence ; Clone Cells/immunology ; Conserved Sequence ; DNA Primers/genetics ; Female ; Genes, T-Cell Receptor beta ; Interferon-gamma/biosynthesis ; Islets of Langerhans/immunology ; Islets of Langerhans/pathology ; Male ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Mice, Transgenic ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function.
Autorzy :
Thomas S; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Mohammed F; Cancer Immunology and Immunotherapy Centre, Institute for Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Reijmers RM; Department of Hematology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Woolston A; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Stauss T; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Kennedy A; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Stirling D; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Holler A; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Green L; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Jones D; Department of Computer Science, University College London, London, WC1E 6BT, UK.
Matthews KK; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, CF10 3AT, UK.
Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, CF10 3AT, UK.
Chain BM; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Heemskerk MHM; Department of Hematology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
Morris EC; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK.
Willcox BE; Cancer Immunology and Immunotherapy Centre, Institute for Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Stauss HJ; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London, NW3 2PF, UK. .
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Źródło :
Nature communications [Nat Commun] 2019 Oct 01; Vol. 10 (1), pp. 4451. Date of Electronic Publication: 2019 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Engineering*
Antigens/*immunology
Genes, T-Cell Receptor/*genetics
Genes, T-Cell Receptor/*immunology
Receptors, Antigen, T-Cell/*genetics
Receptors, Antigen, T-Cell/*metabolism
T-Lymphocytes/*metabolism
Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Cytokines/metabolism ; Gene Expression ; Genetic Therapy ; Humans ; Lectins, C-Type/metabolism ; Lymphocyte Activation ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Models, Molecular ; Protein Domains ; Protein Engineering ; Receptors, Antigen, T-Cell/chemistry ; Receptors, Antigen, T-Cell/immunology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Restricted T cell receptor BV gene usage in the lungs and muscles of patients with idiopathic inflammatory myopathies.
Autorzy :
Englund P; Karolinska University Hospital at Solna, and Karolinska Institutet, Stockholm, Sweden.
Wahlström J
Fathi M
Rasmussen E
Grunewald J
Tornling G
Lundberg IE
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Źródło :
Arthritis and rheumatism [Arthritis Rheum] 2007 Jan; Vol. 56 (1), pp. 372-83.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Dermatomyositis/*genetics
Lung/*metabolism
Muscle, Skeletal/*metabolism
Polymyositis/*genetics
Receptors, Antigen, T-Cell/*genetics
Adult ; Aged ; Bronchoalveolar Lavage ; CD4-Positive T-Lymphocytes/metabolism ; CD4-Positive T-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/pathology ; Complementarity Determining Regions/genetics ; Dermatomyositis/metabolism ; Dermatomyositis/pathology ; Female ; Gene Frequency ; Genes, T-Cell Receptor alpha ; Haplotypes ; Humans ; Lung/pathology ; Male ; Middle Aged ; Muscle, Skeletal/pathology ; Polymyositis/metabolism ; Polymyositis/pathology ; Receptors, Antigen, T-Cell/metabolism
Czasopismo naukowe
Tytuł :
Recognition of Listeria Infection by Germline Elements of the Vγ1.1 Vδ6.3 TCR.
Autorzy :
Negroni MP; Graduate Program in Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655; and.; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Cho OH; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Stern LJ; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605 .
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Źródło :
ImmunoHorizons [Immunohorizons] 2019 Jul 18; Vol. 3 (7), pp. 341-351. Date of Electronic Publication: 2019 Jul 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Complementarity Determining Regions/*genetics
Germ Cells/*chemistry
Listeria/*immunology
Listeriosis/*microbiology
Receptors, Antigen, T-Cell, gamma-delta/*immunology
Amino Acid Sequence ; Animals ; Cells, Cultured ; Genes, T-Cell Receptor delta/genetics ; Genes, T-Cell Receptor gamma/genetics ; Hybridomas/immunology ; Hybridomas/microbiology ; Interleukin-2/metabolism ; Intraepithelial Lymphocytes/immunology ; Lymphocyte Activation/immunology ; Macrophages/immunology ; Macrophages/microbiology ; Mice ; Mice, Inbred C57BL ; Natural Killer T-Cells/immunology ; Receptors, Antigen, T-Cell, gamma-delta/classification ; Transfection
Czasopismo naukowe
Tytuł :
Expression of TCR genes in adult and larval Xenopus laevis.
Autorzy :
Foulkrod AM; Chatham University, Woodland Road, Pittsburgh, PA, 15232, USA.
Appasamy PM; Chatham University, Woodland Road, Pittsburgh, PA, 15232, USA. Electronic address: .
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Źródło :
Developmental and comparative immunology [Dev Comp Immunol] 2019 Jul; Vol. 96, pp. 78-82. Date of Electronic Publication: 2019 Feb 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Larva/*immunology
Receptors, Antigen, T-Cell, gamma-delta/*metabolism
T-Lymphocyte Subsets/*metabolism
Xenopus laevis/*immunology
Animals ; Cell Differentiation/immunology ; Genes, T-Cell Receptor delta ; Genes, T-Cell Receptor gamma ; Homeodomain Proteins/immunology ; Homeodomain Proteins/metabolism ; Larva/genetics ; Larva/metabolism ; Metamorphosis, Biological ; Receptors, Antigen, T-Cell, gamma-delta/genetics ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; T-Lymphocyte Subsets/immunology ; Xenopus laevis/genetics ; Xenopus laevis/metabolism
Czasopismo naukowe
Tytuł :
[Immunoglobulin and T cell receptor gene rearrangement detection: a comparison of two different technologies].
Autorzy :
Xu J
Zhang KP
Ge Y
Yan LX
Zhu XL
Zhuang HG
Liu YH
Pokaż więcej
Źródło :
Zhonghua bing li xue za zhi = Chinese journal of pathology [Zhonghua Bing Li Xue Za Zhi] 2017 May 08; Vol. 46 (5), pp. 342-344.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Gene Rearrangement*
Genes, Immunoglobulin*
Genes, T-Cell Receptor*
Immunoglobulins/*genetics
Genetic Techniques ; Humans
Czasopismo naukowe
Tytuł :
[iNKT cells: potential therapeutic targets to fight anthrax].
Autorzy :
Le Gars M; Pathogénie des toxi-infections bactériennes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France - Blish lab, department of medicine, Stanford immunology, Stanford university, Stanford, CA, États-Unis.
Haustant M; Pathogénie des toxi-infections bactériennes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France.
Klezovich-Benard M; Pathogénie des toxi-infections bactériennes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France.
Paget C; Centre d'infection et d'immunité de Lille, Inserm U1019, CNRS UMR 8204, université de Lille, CHU Lille et Institut Pasteur de Lille, 1, rue du professeur Calmette, 59000 Lille, France.
Trottein F; Centre d'infection et d'immunité de Lille, Inserm U1019, CNRS UMR 8204, université de Lille, CHU Lille et Institut Pasteur de Lille, 1, rue du professeur Calmette, 59000 Lille, France.
Goossens PL; Pathogénie des toxi-infections bactériennes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France.
Tournier JN; Pathogénie des toxi-infections bactériennes, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, France - Unité interactions hôte-agents pathogènes, institut de recherche biomédicale des armées, BP73, 91223 Brétigny-sur-Orge, France.
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Transliterated Title :
Quand les cellules iNKT partent au charbon : nouvelles pistes thérapeutiques.
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2017 May; Vol. 33 (5), pp. 488-490. Date of Electronic Publication: 2017 Jun 14.
Typ publikacji :
Wiadomości
MeSH Terms :
Genes, T-Cell Receptor*
Anthrax/*therapy
Bacillus anthracis/*immunology
Molecular Targeted Therapy/*methods
Natural Killer T-Cells/*metabolism
Natural Killer T-Cells/*transplantation
Animals ; Anthrax/genetics ; Anthrax/immunology ; Genetic Therapy/methods ; Humans ; Immunity, Cellular/genetics ; Immunotherapy, Adoptive/methods ; Lymph Nodes/metabolism ; Lymph Nodes/microbiology ; Mice
Periodyk
Tytuł :
γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function.
Autorzy :
Tao C; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
Shao H; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
Zhang W; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
Bo H; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
Wu F; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
Shen H; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
Huang S; Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2017 Apr; Vol. 15 (4), pp. 1555-1564. Date of Electronic Publication: 2017 Feb 15.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Receptors, Antigen, T-Cell, alpha-beta/*chemistry
Receptors, Antigen, T-Cell, alpha-beta/*metabolism
Receptors, Antigen, T-Cell, gamma-delta/*chemistry
Receptors, Antigen, T-Cell, gamma-delta/*metabolism
T-Lymphocytes/*metabolism
Adult ; Female ; Humans ; Jurkat Cells ; Leukocytes, Mononuclear/metabolism ; Male ; Protein Domains ; Transduction, Genetic ; Young Adult
Czasopismo naukowe
Tytuł :
Perspectives: transcription. A tail of histone acetylation and DNA recombination.
Autorzy :
Schlissel MS; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2000 Jan 21; Vol. 287 (5452), pp. 438-40.
Typ publikacji :
Comment; Journal Article
MeSH Terms :
Gene Rearrangement*
Genes, Immunoglobulin*
Genes, T-Cell Receptor*
Recombination, Genetic*
Saccharomyces cerevisiae Proteins*
Histones/*metabolism
Acetylation ; Acetyltransferases/metabolism ; Chromatin/metabolism ; DNA Nucleotidyltransferases/metabolism ; Enhancer Elements, Genetic ; Gene Rearrangement, T-Lymphocyte ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor delta ; Histone Acetyltransferases ; Nucleosomes/chemistry ; Nucleosomes/ultrastructure ; Transcription Factors ; Transcription, Genetic ; VDJ Recombinases
Czasopismo naukowe

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