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Wyszukujesz frazę ""T cell receptor"" wg kryterium: Temat


Tytuł :
Comprehensive analysis of T-cell receptor repertoire in patients with acute coronary syndrome by high-throughput sequencing.
Autorzy :
Liu S; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China. .; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China. .
Zhong Z; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizho, 514031, P. R. China.; Center for Cardiovascular Diseases, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, 514031, P. R. China.
Zhong W; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizho, 514031, P. R. China.; Center for Cardiovascular Diseases, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, 514031, P. R. China.
Weng R; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
Liu J; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
Gu X; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
Chen Y; Clinical Core Laboratory, Meizhou People's Hospital (Huangtang Hospital), Meizhou Hospital Affiliated to Sun Yat-sen University, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population, Meizhou, 514031, P. R. China.
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Źródło :
BMC cardiovascular disorders [BMC Cardiovasc Disord] 2020 May 27; Vol. 20 (1), pp. 253. Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
High-Throughput Nucleotide Sequencing*
Acute Coronary Syndrome/*genetics
Angina, Unstable/*genetics
Myocardial Infarction/*genetics
T-Lymphocytes/*immunology
Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/immunology ; Aged ; Angina, Unstable/diagnosis ; Angina, Unstable/immunology ; Case-Control Studies ; China ; Complementarity Determining Regions/genetics ; Female ; Genes, T-Cell Receptor beta/genetics ; Humans ; Immunoglobulin Variable Region ; Male ; Middle Aged ; Myocardial Infarction/diagnosis ; Myocardial Infarction/immunology
Czasopismo naukowe
Tytuł :
Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature.
Autorzy :
Kelkka T; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Savola P; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Bhattacharya D; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Huuhtanen J; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Lönnberg T; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Kankainen M; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Paalanen K; Rheumatology, Jyväskylä Central Hospital, Jyväskylä, Finland.
Tyster M; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Lepistö M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Ellonen P; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Smolander J; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Eldfors S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Yadav B; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
Khan S; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Koivuniemi R; Rheumatology, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.
Sjöwall C; Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection, Linköping University, Linköping, Sweden.
Elo LL; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.
Lähdesmäki H; Department of Computer Science, Aalto University School of Science, Espoo, Finland.
Maeda Y; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Tokyo, Japan.
Nishikawa H; Division of Cancer Immunology, Research Institute/Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Tokyo, Japan.
Leirisalo-Repo M; Rheumatology, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.
Sokka-Isler T; Rheumatology, Jyväskylä Central Hospital, Jyväskylä, Finland.; University of Eastern Finland, Faculty of Health Sciences, Kuopio, Finland.
Mustjoki S; Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Nov 19; Vol. 11, pp. 578848. Date of Electronic Publication: 2020 Nov 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Transcriptome*
Anti-Citrullinated Protein Antibodies/*blood
Arthritis, Rheumatoid/*genetics
Cytokines/*genetics
T-Lymphocytes, Cytotoxic/*metabolism
Adolescent ; Adult ; Aged ; Arthritis, Rheumatoid/blood ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/immunology ; Biomarkers/blood ; Case-Control Studies ; Cytokines/metabolism ; Female ; Gene Expression Profiling ; Humans ; Male ; Middle Aged ; Mutation ; Phenotype ; RNA-Seq ; Severity of Illness Index ; Single-Cell Analysis ; T-Lymphocytes, Cytotoxic/immunology ; Whole Exome Sequencing ; Young Adult
Czasopismo naukowe
Tytuł :
Regulation of T-cell Receptor Gene Expression by Three-Dimensional Locus Conformation and Enhancer Function.
Autorzy :
Rodríguez-Caparrós A; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Álvarez-Santiago J; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Del Valle-Pastor MJ; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Suñé C; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
López-Ros J; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Hernández-Munain C; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 11; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Enhancer Elements, Genetic/*genetics
Gene Expression Regulation/*genetics
Genes, T-Cell Receptor/*genetics
T-Lymphocytes/*immunology
Animals ; Chromatin/genetics ; Chromatin/immunology ; Enhancer Elements, Genetic/immunology ; Gene Expression Regulation/immunology ; Genes, T-Cell Receptor/immunology ; Humans ; Signal Transduction/genetics ; Signal Transduction/immunology ; Transcription, Genetic/genetics ; Transcription, Genetic/immunology ; V(D)J Recombination/genetics ; V(D)J Recombination/immunology
Czasopismo naukowe
Tytuł :
The expansion of the TRB and TRG genes in domestic goats (Capra hircus) is characteristic of the ruminant species.
Autorzy :
Giannico F; Department of Veterinary Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Massari S; Department of Biological and Environmental Science and Technologies, University of Salento, Lecce, Italy.
Caputi Jambrenghi A; Department of Agricultural and Environmental Science, University of Bari 'Aldo Moro', Bari, Italy.
Soriano A; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Pala A; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Linguiti G; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Ciccarese S; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy.
Antonacci R; Department of Biology, University of Bari 'Aldo Moro', 70124, Bari, Italy. .
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Źródło :
BMC genomics [BMC Genomics] 2020 Sep 11; Vol. 21 (1), pp. 623. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Genes, T-Cell Receptor beta*
Genes, T-Cell Receptor gamma*
Goats/*genetics
Animals ; Gene Dosage ; Goats/classification ; Phylogeny
Czasopismo naukowe
Tytuł :
Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases.
Autorzy :
Rosati E; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Pogorelyy MV; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.
Dowds CM; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Moller FT; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Sorensen SB; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Lebedev YB; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.
Frey N; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany.
Schreiber S; Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany.
Spehlmann ME; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany.
Andersen V; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; IRS-Center Sønderjylland, University of Southern Denmark, Odense, Denmark.
Mamedov IZ; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.; Laboratory of molecular biology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.; CEITEC, Masaryk University, Brno, Czech Republic.
Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
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Źródło :
Journal of Crohn's & colitis [J Crohns Colitis] 2020 Jul 09; Vol. 14 (6), pp. 778-790.
Typ publikacji :
Journal Article; Twin Study
MeSH Terms :
Colitis, Ulcerative*/diagnosis
Colitis, Ulcerative*/immunology
Colitis, Ulcerative*/physiopathology
Crohn Disease*/diagnosis
Crohn Disease*/immunology
Crohn Disease*/physiopathology
Genes, T-Cell Receptor alpha*
Genes, T-Cell Receptor beta*
Receptors, Antigen, T-Cell, alpha-beta/*blood
Adult ; C-Reactive Protein/analysis ; Denmark ; Feces ; Female ; Germany ; Humans ; Leukocyte L1 Antigen Complex/analysis ; Male ; Patient Acuity ; Sequence Analysis, DNA ; Smoking/immunology ; Twins, Monozygotic
Czasopismo naukowe
Tytuł :
Replacement of TCR Dβ With Immunoglobulin D H DSP2.3 Imposes a Tyrosine-Enriched TCR Repertoire and Adversely Affects T Cell Development.
Autorzy :
Levinson M; Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Khass M; Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Division of Genetic Engineering and Biotechnology, National Research Center, Cairo, Egypt.
Burrows PD; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Schroeder HW Jr; Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Sep 29; Vol. 11, pp. 573413. Date of Electronic Publication: 2020 Sep 29 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Complementarity Determining Regions*
Genes, Immunoglobulin Heavy Chain*
Genes, T-Cell Receptor beta*
Immunoglobulin Heavy Chains/*metabolism
Receptors, Antigen, T-Cell, alpha-beta/*metabolism
T-Lymphocytes/*metabolism
Thymocytes/*metabolism
Animals ; Immunization ; Immunodominant Epitopes ; Immunoglobulin Heavy Chains/genetics ; Lymphocyte Activation ; Mice, Inbred C57BL ; Mice, Knockout ; Ovalbumin/administration & dosage ; Ovalbumin/immunology ; Phenotype ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; T-Lymphocytes/immunology ; Thymocytes/immunology ; Tyrosine
Czasopismo naukowe
Tytuł :
TCR-Seq Identifies Distinct Repertoires of Distant-Metastatic and Nondistant-Metastatic Thyroid Tumors.
Autorzy :
Lan X; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Cao J; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Ye K; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.; Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhang C; Geneplus-Shenzhen, Shenzhen, China.
Zhang Q; Zhejiang Chinese Medical University, Hangzhou, China.
Ge X; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.; Heartland Christian School, Columbiana, Ohio, USA.
Wang C; Geneplus-Shenzhen, Shenzhen, China.; School of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Zhang C; Geneplus-Beijing, Beijing, China.
Tai Z; Geneplus-Shenzhen, Shenzhen, China.
Wei W; Geneplus-Shenzhen, Shenzhen, China.
Huang Y; Geneplus-Shenzhen, Shenzhen, China.
Yi X; Geneplus-Shenzhen, Shenzhen, China.
Tan Z; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Zheng C; Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, China.
Chen C; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Zhu X; Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Wang J; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Xu J; Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, China.
Zhu X; Department of Head and Neck Surgery, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
Ge M; Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang Province, China.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Sep 01; Vol. 105 (9).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Lymphocytes, Tumor-Infiltrating/*metabolism
Thyroid Cancer, Papillary/*genetics
Thyroid Cancer, Papillary/*pathology
Thyroid Neoplasms/*genetics
Thyroid Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Female ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; Retrospective Studies ; Thyroid Nodule/genetics ; Thyroid Nodule/pathology
Czasopismo naukowe
Tytuł :
Clinical and cytopathological characteristics of HTLV-1 hodgkin lymphoma.
Autorzy :
Kobata K; Division of Diagnostic Pathology, Faculty of Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Kimura S; Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Mihashi Y; Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.; Departments of Otolaryngology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Iwasaki H; Departments of Hematology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
Nonaka S; Departments of Pathology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
Matsumoto S; Division of Diagnostic Pathology, Faculty of Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Takamatsu Y; Division of Medical Oncology, Hematology and Infectious Diseases, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Choi I; Department of Hematology, National Hospital Organization, Kyushu Cancer Center, Fukuoka, Japan.
Kawauchi S; Departments of Pathology, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan.
Ishitsuka K; Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.
Takeshita M; Division of Diagnostic Pathology, Faculty of Medicine, Fukuoka University Hospital, Fukuoka, Japan.; Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
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Źródło :
Cancer medicine [Cancer Med] 2020 Aug; Vol. 9 (16), pp. 5788-5797. Date of Electronic Publication: 2020 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor*
Genes, T-Cell Receptor beta*
Hodgkin Disease*/genetics
Hodgkin Disease*/mortality
Hodgkin Disease*/pathology
Human T-lymphotropic virus 1*/genetics
Leukemia-Lymphoma, Adult T-Cell*/genetics
Leukemia-Lymphoma, Adult T-Cell*/mortality
Leukemia-Lymphoma, Adult T-Cell*/pathology
Adult ; Aged ; Antigens, CD20/metabolism ; Cell Size ; DNA, Viral ; Epstein-Barr Virus Infections ; Female ; Humans ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Middle Aged ; Reed-Sternberg Cells ; Virus Integration/genetics
Czasopismo naukowe
Tytuł :
Diagnostic Value of Genotypic Analysis in Primary Cutaneous Lymphomas using Standardized BIOMED-2 Polymerase Chain Reaction Protocols: Experience in Daily Clinical Practice.
Autorzy :
LÓPEZ AVENTÍN, Daniel
GALLARDO, Fernando
COLOMO, Luis
MORAGÓN, Ester
VELA, María Carmen
DURAN JORDÀ, Xavier
BELLOSILLO, Beatriz
PUJOL, Ramon M.
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Źródło :
Acta Dermato-Venereologica. May2021, Vol. 101 Issue 5, p1-7. 7p.
Czasopismo naukowe
Tytuł :
IMGT® Biocuration and Comparative Study of the T Cell Receptor Beta Locus of Veterinary Species Based on Homo sapiens TRB.
Autorzy :
Pégorier P; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Bertignac M; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Chentli I; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Nguefack Ngoune V; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Folch G; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Jabado-Michaloud J; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Hadi-Saljoqi S; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Giudicelli V; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Duroux P; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Lefranc MP; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
Kossida S; IMGT®, The International ImMunoGeneTics Information System®, Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Humaine (IGH), Université de Montpellier (UM), Montpellier, France.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 May 05; Vol. 11, pp. 821. Date of Electronic Publication: 2020 May 05 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Genetic Loci*
Computational Biology/*methods
Immunogenetics/*methods
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Animals ; Cats ; Databases, Genetic ; Dogs ; Ferrets/genetics ; Ferrets/immunology ; Humans ; Macaca mulatta/genetics ; Macaca mulatta/immunology ; Multigene Family ; Phylogeny ; Rabbits ; Sheep/genetics ; Sheep/immunology ; Swine/genetics ; Swine/immunology
Czasopismo naukowe
Tytuł :
T cell receptor gene recombinations in human tumor specimen exome files: detection of T cell receptor-β VDJ recombinations associates with a favorable oncologic outcome for bladder cancer.
Autorzy :
Samy MD; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA.
Tong WL; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA.
Yavorski JM; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA.
Sexton WJ; Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Blanck G; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Bd., Tampa, FL, 33612, USA. .; Immunology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2017 Mar; Vol. 66 (3), pp. 403-410. Date of Electronic Publication: 2016 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Urinary Bladder Neoplasms/*genetics
V(D)J Recombination/*genetics
Exome ; Genes, T-Cell Receptor beta ; Humans ; Treatment Outcome ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Nodal EBV-positive polymorphic B cell lymphoproliferative disorder with plasma cell differentiation: clinicopathological analysis of five cases.
Autorzy :
Satou A; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan. .
Tabata T; Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
Suzuki Y; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Sato Y; Division of Pathophysiology, Okayama University Graduate School of Health Sciences, Okayama, Japan.
Tahara I; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Mochizuki K; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Oishi N; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Takahara T; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan.
Yoshino T; Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
Tsuzuki T; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan.
Nakamura S; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 May; Vol. 478 (5), pp. 969-976. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
B-Lymphocytes/*pathology
Epstein-Barr Virus Infections/*pathology
Herpesvirus 4, Human/*pathogenicity
Lymphoma, Large B-Cell, Diffuse/*pathology
Lymphoproliferative Disorders/*pathology
Plasma Cells/*pathology
Aged ; Aged, 80 and over ; Antirheumatic Agents/adverse effects ; B-Lymphocytes/immunology ; B-Lymphocytes/virology ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Diagnosis, Differential ; Epstein-Barr Virus Infections/genetics ; Epstein-Barr Virus Infections/immunology ; Epstein-Barr Virus Infections/virology ; Female ; Genes, Immunoglobulin Heavy Chain ; Genes, T-Cell Receptor gamma ; Herpesvirus 4, Human/genetics ; Herpesvirus 4, Human/immunology ; Host-Pathogen Interactions ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/immunology ; Lymphoma, Large B-Cell, Diffuse/virology ; Lymphoproliferative Disorders/genetics ; Lymphoproliferative Disorders/immunology ; Lymphoproliferative Disorders/virology ; Male ; Methotrexate/adverse effects ; Plasma Cells/immunology ; Plasma Cells/virology ; Predictive Value of Tests ; Risk Factors
Czasopismo naukowe
Tytuł :
High-throughput sequencing reveals the diversity of TCR β chain CDR3 repertoire in patients with severe acne.
Autorzy :
Shao L; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Liu Y; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Mei J; BGI Genomics, BGI-Shenzhen, Shenzhen 518083, PR China.
Li D; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, USA.
Chen L; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Pan Q; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Zhang S; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Dai X; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China.
Liang J; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China. Electronic address: .
Sun S; BGI Genomics, BGI-Shenzhen, Shenzhen 518083, PR China. Electronic address: .
Wang J; Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, PR China; Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, PR China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Apr; Vol. 120, pp. 23-31. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta*
Acne Vulgaris/*genetics
Acne Vulgaris/*immunology
Complementarity Determining Regions/*genetics
Adolescent ; Amino Acid Sequence ; Base Sequence ; Genetic Variation ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Multiplex Polymerase Chain Reaction ; Sequence Analysis, DNA ; Sequence Analysis, Protein ; Young Adult
Czasopismo naukowe
Tytuł :
Differential Diagnosis of Interstitial Allograft Rejection and BKV Nephropathy by T-cell Receptor Sequencing.
Autorzy :
Stervbo U; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.
Nienen M; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Immunology, Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin, Germany.
Hecht J; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
Viebahn R; Department of Surgery, Ruhr-University Bochum, Knappschaftskrankenhaus, Bochum, Germany.
Amann K; Department Nephropathology, University Hospital Erlangen, Erlangen, Germany.
Westhoff TH; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.
Babel N; Medical Department I, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Herne, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.
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Źródło :
Transplantation [Transplantation] 2020 Apr; Vol. 104 (4), pp. e107-e108.
Typ publikacji :
Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
Sequence Analysis, DNA*
BK Virus/*pathogenicity
Graft Rejection/*diagnosis
Kidney Transplantation/*adverse effects
Opportunistic Infections/*diagnosis
Polyomavirus Infections/*diagnosis
Tumor Virus Infections/*diagnosis
BK Virus/immunology ; Diagnosis, Differential ; Graft Rejection/genetics ; Graft Rejection/immunology ; Graft Rejection/prevention & control ; High-Throughput Nucleotide Sequencing ; Humans ; Immunocompromised Host ; Immunosuppressive Agents/adverse effects ; Male ; Opportunistic Infections/genetics ; Opportunistic Infections/immunology ; Opportunistic Infections/virology ; Polyomavirus Infections/genetics ; Polyomavirus Infections/immunology ; Polyomavirus Infections/virology ; Predictive Value of Tests ; Treatment Outcome ; Tumor Virus Infections/genetics ; Tumor Virus Infections/immunology ; Tumor Virus Infections/virology ; Viral Load ; Young Adult
Raport
Tytuł :
Overview of the Germline and Expressed Repertoires of the TRB Genes in Sus scrofa .
Autorzy :
Massari S; Department of Biological and Environmental Science and Technologies, University of Salento, Lecce, Italy.
Bellini M; Department of Biology, University of Bari 'Aldo Moro', Bari, Italy.
Ciccarese S; Department of Biology, University of Bari 'Aldo Moro', Bari, Italy.
Antonacci R; Department of Biology, University of Bari 'Aldo Moro', Bari, Italy.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 Nov 05; Vol. 9, pp. 2526. Date of Electronic Publication: 2018 Nov 05 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor beta/*genetics
Receptors, Antigen, T-Cell, alpha-beta/*genetics
T-Lymphocytes/*immunology
Adaptive Immunity/genetics ; Adaptive Immunity/immunology ; Amino Acid Sequence/genetics ; Animals ; Genes, T-Cell Receptor alpha/genetics ; Genome/genetics ; Polymorphism, Single Nucleotide/genetics ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Sus scrofa ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Dissection of the Human T-Cell Receptor γ Gene Repertoire in the Brain and Peripheral Blood Identifies Age- and Alzheimer's Disease-Associated Clonotype Profiles.
Autorzy :
Aliseychik M; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.; Center for Genetics and Genetic Technologies, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Patrikeev A; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Gusev F; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Grigorenko A; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Andreeva T; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.; Center for Genetics and Genetic Technologies, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Biragyn A; Immunoregulation Section, National Institute on Aging, Baltimore, MD, United States.
Rogaev E; Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, United States.; Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.; Center for Genetics and Genetic Technologies, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Jan 29; Vol. 11, pp. 12. Date of Electronic Publication: 2020 Jan 29 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor gamma*
Aging/*blood
Aging/*immunology
Alzheimer Disease/*blood
Alzheimer Disease/*immunology
Brain/*immunology
Clone Cells/*immunology
Receptors, Antigen, T-Cell, gamma-delta/*genetics
Adult ; Aged ; Aged, 80 and over ; Complementarity Determining Regions/genetics ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Pilot Projects ; Receptors, Antigen, T-Cell, gamma-delta/blood ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
The Genome Resequencing of TCR Loci in Gallus gallus Revealed Their Distinct Evolutionary Features in Avians.
Autorzy :
Liu F; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Li J; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.; College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Lin IYC; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Yang X; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Ma J; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Chen Y; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Lv N; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.
Shi Y; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Gao GF; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Zhu B; Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; .; Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing 100101, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China; and.; Department of Pathogenic Biology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan 646000, China.
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Źródło :
ImmunoHorizons [Immunohorizons] 2020 Jan 28; Vol. 4 (1), pp. 33-46. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Receptors, Antigen, T-Cell/*genetics
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Receptors, Antigen, T-Cell, gamma-delta/*genetics
Animals ; Biological Evolution ; Chickens ; Chromosome Mapping ; Evolution, Molecular ; Genomics ; Phylogeny ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
Detection of neoantigen-reactive T cell clones based on the clonal expansion using next-generation sequencing of T cell receptor β complementarity-determining region 3.
Autorzy :
Sumimoto H; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan. Electronic address: .
Takano A; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address: .
Teramoto K; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan. Electronic address: .
Daigo Y; Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2020 Jan; Vol. 476, pp. 112679. Date of Electronic Publication: 2019 Oct 23.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epitopes*
Genes, T-Cell Receptor beta*
High-Throughput Nucleotide Sequencing*
Antigens, Neoplasm/*immunology
Clone Cells/*immunology
Complementarity Determining Regions/*genetics
T-Lymphocytes/*immunology
Aged ; Cell Separation/methods ; Enzyme-Linked Immunospot Assay ; Female ; Humans ; Lung Neoplasms/immunology ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Two Successive Inversional Vβ Rearrangements on a Single Tcrb Allele Can Contribute to the TCRβ Repertoire.
Autorzy :
Lee KD; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Bassing CH; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Jan 01; Vol. 204 (1), pp. 78-86. Date of Electronic Publication: 2019 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor beta/*genetics
Alleles ; Animals ; Genes, T-Cell Receptor beta/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
A systematic analysis of immune genes and overall survival in cancer patients.
Autorzy :
Wang Q; Center for Public Health Informatics, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, People's Republic of China.
Li P; Center for Public Health Informatics, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, People's Republic of China. .
Wu W; Center for Public Health Informatics, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, People's Republic of China. .
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Źródło :
BMC cancer [BMC Cancer] 2019 Dec 16; Vol. 19 (1), pp. 1225. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, T-Cell Receptor*
Signal Transduction*
Neoplasms/*immunology
Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasms/diagnosis ; Neoplasms/genetics ; Neoplasms/metabolism ; Prognosis ; Survival Analysis
Czasopismo naukowe
Tytuł :
Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors.
Autorzy :
Mika J; Data Mining Division, Silesian University of Technology, Gliwice, Poland.
Kabacik S; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards Public Health England Chilton, Didcot, United Kingdom.
Badie C; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards Public Health England Chilton, Didcot, United Kingdom.
Polanska J; Data Mining Division, Silesian University of Technology, Gliwice, Poland.
Candéias SM; Université Grenoble Alpes, CEA, CNRS, IRIG-LCBM, Grenoble, France.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Nov 08; Vol. 10, pp. 2637. Date of Electronic Publication: 2019 Nov 08 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, T-Cell Receptor*
V(D)J Recombination*
Animals ; DNA ; Humans ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred CBA ; VDJ Recombinases
Czasopismo naukowe
Tytuł :
Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy.
Autorzy :
Spear TT; Department of Surgery, Cardinal Bernardin Cancer Center, Loyola University Chicago, 2160 S. 1st Ave, Bldg 112, Room 308, Maywood, IL, 60153, USA. .
Evavold BD; Department of Pathology, Microbiology and Immunology, University of Utah, Salt Lake City, UT, 84112, USA.
Baker BM; Department of Chemistry and Biochemistry, Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, 46530, USA.
Nishimura MI; Department of Surgery, Cardinal Bernardin Cancer Center, Loyola University Chicago, 2160 S. 1st Ave, Bldg 112, Room 308, Maywood, IL, 60153, USA.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2019 Nov; Vol. 68 (11), pp. 1881-1889. Date of Electronic Publication: 2019 Oct 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunotherapy*
Cytotoxicity, Immunologic/*immunology
Genes, T-Cell Receptor/*immunology
Neoplasms/*therapy
T-Lymphocytes/*immunology
T-Lymphocytes/*transplantation
Animals ; Antibody Specificity ; Cross Reactions ; Genes, T-Cell Receptor/genetics ; Humans ; Neoplasms/immunology ; Neoplasms/metabolism ; T-Cell Antigen Receptor Specificity ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Tumor hypoxia represses γδ T cell-mediated antitumor immunity against brain tumors.
Autorzy :
Park JH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Kim HJ; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Kim CW; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Kim HC; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Jung Y; Department of Bio and Brain Engineering, KAIST, Daejeon, Republic of Korea.
Lee HS; Department of Bio and Brain Engineering, KAIST, Daejeon, Republic of Korea.
Lee Y; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Ju YS; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.; BioMedical Research Center, KAIST, Daejeon, Republic of Korea.
Oh JE; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.; BioMedical Research Center, KAIST, Daejeon, Republic of Korea.
Park SH; Department of Bio and Brain Engineering, KAIST, Daejeon, Republic of Korea.
Lee JH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.; BioMedical Research Center, KAIST, Daejeon, Republic of Korea.
Lee SK; Department of Obstetrics and Gynecology, College of Medicine, Myunggok Medical Research Center, Konyang University, Daejeon, Republic of Korea.
Lee HK; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea. .; BioMedical Research Center, KAIST, Daejeon, Republic of Korea. .
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Źródło :
Nature immunology [Nat Immunol] 2021 Mar; Vol. 22 (3), pp. 336-346. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytotoxicity, Immunologic*
Tumor Escape*
Tumor Microenvironment*
Brain Neoplasms/*immunology
Glioblastoma/*immunology
Intraepithelial Lymphocytes/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Animals ; Apoptosis ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; CD8 Antigens/genetics ; CD8 Antigens/metabolism ; Cell Line, Tumor ; Coculture Techniques ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Gene Expression Regulation, Neoplastic ; Genes, T-Cell Receptor delta ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Intraepithelial Lymphocytes/metabolism ; Intraepithelial Lymphocytes/pathology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Male ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Knockout ; Mice, Nude ; NK Cell Lectin-Like Receptor Subfamily K/genetics ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Phenotype ; Signal Transduction ; Tumor Hypoxia
Czasopismo naukowe
Tytuł :
Absence of αβ T cells accelerates disuse bone loss in male mice after spinal cord injury.
Autorzy :
Sahbani K; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.
Shultz LC; Veterinary Medical Unit, James J Peters Veterans Affairs Medical Center, Bronx, New York.
Cardozo CP; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.; Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.; Department of Rehabilitation Medicine and Human Performance, The Icahn School of Medicine at Mount Sinai, New York, New York.
Bauman WA; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.; Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.
Tawfeek HA; National Center for the Medical Consequences of Spinal Cord Injury, James J Peters Veterans Affairs Medical Center, Bronx, New York.; Bronx Veterans Medical Research Foundation Inc., Bronx, New York.; Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.
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Źródło :
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2021 Mar; Vol. 1487 (1), pp. 43-55. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Resorption/*genetics
Genes, T-Cell Receptor beta/*genetics
Spinal Cord Injuries/*complications
T-Lymphocytes/*pathology
Animals ; Bone Density/genetics ; Bone Density/immunology ; Bone Diseases, Metabolic/genetics ; Bone Diseases, Metabolic/immunology ; Bone Diseases, Metabolic/metabolism ; Bone Diseases, Metabolic/pathology ; Bone Resorption/immunology ; Bone Resorption/metabolism ; Cell Count ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Antigen, T-Cell, alpha-beta/deficiency ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; Spinal Cord Injuries/genetics ; Spinal Cord Injuries/immunology ; Spinal Cord Injuries/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; X-Ray Microtomography
Czasopismo naukowe
Tytuł :
Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells.
Autorzy :
Schoettler N; 1Department of Medicine, The University of Chicago, Chicago, USA.; 2Department of Human Genetics, The University of Chicago, Chicago, USA.
Hrusch CL; 1Department of Medicine, The University of Chicago, Chicago, USA.
Blaine KM; 1Department of Medicine, The University of Chicago, Chicago, USA.
Sperling AI; 1Department of Medicine, The University of Chicago, Chicago, USA.
Ober C; 2Department of Human Genetics, The University of Chicago, Chicago, USA.
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Źródło :
Communications biology [Commun Biol] 2019 Nov 13; Vol. 2, pp. 411. Date of Electronic Publication: 2019 Nov 13 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, T-Cell Receptor*
Immunologic Memory*
Transcription, Genetic*
Lung/*immunology
Lymph Nodes/*immunology
T-Lymphocyte Subsets/*immunology
T-Lymphocyte Subsets/*metabolism
Biomarkers ; Cellular Reprogramming/genetics ; Gene Expression Profiling ; Gene Ontology ; Humans ; Immunophenotyping ; Reproducibility of Results ; V(D)J Recombination
Czasopismo naukowe

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