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Wyszukujesz frazę ""T-Lymphocytes"" wg kryterium: Temat


Tytuł:
An angel or a devil? Current view on the role of CD8 T cells in the pathogenesis of myasthenia gravis.
Autorzy:
Peng Y; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China. .; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China. .
Yang H; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen Q; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Jin H; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Xue YH; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Du MQ; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Liu S; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Yao SY; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 20; Vol. 22 (1), pp. 183. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD8-Positive T-Lymphocytes*
Myasthenia Gravis, Autoimmune, Experimental*/metabolism
Animals ; Humans ; T-Lymphocytes, Helper-Inducer/metabolism ; T-Lymphocytes, Regulatory ; Autoantigens/metabolism
Czasopismo naukowe
Tytuł:
Characterization of tumoricidal activities mediated by a novel immune cell regimen composing interferon-producing killer dendritic cells and tumor-specific cytotoxic T lymphocytes.
Autorzy:
Fang CH; Biomedical Industry Ph.D. Program, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; FullHope Biomedical Co.,Ltd, 10F., No. 10, Ln. 609, Sec. 5, Chongxin Rd., Sanchong Dist., New Taipei City, 241405, Taiwan.
Cheng WF; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Cheng YF; FullHope Biomedical Co.,Ltd, 10F., No. 10, Ln. 609, Sec. 5, Chongxin Rd., Sanchong Dist., New Taipei City, 241405, Taiwan.
Lan KL; Department of Heavy Particles & Radiation Oncology, Taipei Veterans General Hospital, Taipei, Taiwan. .; Institute of Traditional Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong St. Beitou Dist., Taipei City, 112304, Taiwan. .
Lee JM; FullHope Biomedical Co.,Ltd, 10F., No. 10, Ln. 609, Sec. 5, Chongxin Rd., Sanchong Dist., New Taipei City, 241405, Taiwan. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Mar 28; Vol. 24 (1), pp. 395. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Cytotoxic*
Ovarian Neoplasms*/metabolism
Female ; Humans ; Interferons/metabolism ; Interferon-gamma/metabolism ; Leukocytes, Mononuclear/metabolism ; Killer Cells, Natural/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Antigens, Neoplasm ; Dendritic Cells
Czasopismo naukowe
Tytuł:
T Cell Responses in Pregnant Women Who Received mRNA-Based Vaccination to Prevent COVID-19 Revealed Unknown Exposure to the Natural Infection and Numerous SARS-CoV-2-Specific CD4- CD8- Double Negative T Cells and Regulatory T Cells.
Autorzy:
Chambers CD; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Song J; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
da Silva Antunes R; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Sette A; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Franco A; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
COVID-19*/prevention & control
Pregnancy ; Female ; Humans ; SARS-CoV-2 ; Pregnant Women ; COVID-19 Vaccines ; Vaccination ; CD8-Positive T-Lymphocytes ; Peptides ; Antibodies, Viral
Czasopismo naukowe
Tytuł:
Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice.
Autorzy:
Hirose M; Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany.; Center of Brain, Behavior and Metabolism, University of Lübeck, 23562 Lübeck, Germany.; Institute of Experimental Dermatology, University of Lübeck, 23562 Lübeck, Germany.
Leliavski A; T-Knife GmbH, 13125 Berlin, Germany.
de Assis LVM; Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany.; Center of Brain, Behavior and Metabolism, University of Lübeck, 23562 Lübeck, Germany.
Matveeva O; Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany.
Skrum L; Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany.; Center of Brain, Behavior and Metabolism, University of Lübeck, 23562 Lübeck, Germany.
Solbach W; Institute for Medical Microbiology and Hygiene, University of Lübeck, 23562 Lübeck, Germany.
Oster H; Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany.; Center of Brain, Behavior and Metabolism, University of Lübeck, 23562 Lübeck, Germany.
Heyde I; Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany.; Center of Brain, Behavior and Metabolism, University of Lübeck, 23562 Lübeck, Germany.
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Źródło:
Cells [Cells] 2024 Jan 13; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Encephalomyelitis, Autoimmune, Experimental*
Animals ; Mice ; Inflammation ; Circadian Rhythm ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Patients with Chronic Spinal Cord Injury Display a Progressive Alteration over the Years of the Activation Stages of the T Lymphocyte Compartment.
Autorzy:
Haro S; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Gomez-Lahoz AM; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Monserrat J; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Atienza-Pérez M; Service of Rehabilitation, National Hospital for Paraplegic Patients, Carr. de la Peraleda, S/N, 45004 Toledo, Spain.
Fraile-Martinez O; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Ortega MA; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
García-Montero C; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Díaz D; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.
Lopez-Dolado E; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Service of Rehabilitation, National Hospital for Paraplegic Patients, Carr. de la Peraleda, S/N, 45004 Toledo, Spain.
Álvarez-Mon M; Department of Medicine and Medical Specialities, University of Alcala, Crta N-II km 33.6, 28871 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.; Immune System Diseases-Rheumatology Service and Internal Medicine, Prince of Asturias University Hospital (CIBEREHD), 28806 Alcala de Henares, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 18; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
Spinal Cord Injuries*/metabolism
Humans ; CD4-Positive T-Lymphocytes ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
The triple-drug combination DBDx enhances the antitumor efficacy of PD-1 antibody associated with Treg modulation.
Autorzy:
Shan C; Department of Oncology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, P.R. China.; Jiangsu Alphamab Biopharmaceuticals Co., Ltd, Suzhou, P.R. China.
Wang Y; Department of Oncology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, P.R. China.; Zibo Central Hospital, Zibo, P.R. China.
Li Y; Department of Oncology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, P.R. China.
Yang S; Department of Oncology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, P.R. China.; Qujing Center for Disease Control and Prevention, Qujing, P.R. China.
Sheng W; Department of Oncology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, P.R. China.
Liu X; Department of Oncology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou, P.R. China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Dec 01; Vol. 19 (6), pp. 1603-1609. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
Carcinoma, Lewis Lung*/drug therapy
Animals ; Mice ; Programmed Cell Death 1 Receptor ; Cell Line, Tumor ; CD8-Positive T-Lymphocytes ; Drug Combinations ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Osteogenic Differentiation of Human Periodontal Ligament Stromal Cells Influences Their Immunosuppressive Potential toward Allogenic CD4 T Cells.
Autorzy:
Miłek O; Competence Center for Periodontal Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Tur D; Clinical Division of Periodontology, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Ahčin L; Competence Center for Periodontal Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Voitseshyna O; Competence Center for Periodontal Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Behm C; Competence Center for Periodontal Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Andrukhov O; Competence Center for Periodontal Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 17; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*/metabolism
Mesenchymal Stem Cells*/metabolism
Humans ; Periodontal Ligament/metabolism ; Osteogenesis ; Cell Differentiation ; Tumor Necrosis Factor-alpha/metabolism ; Immunosuppressive Agents/pharmacology ; CD4-Positive T-Lymphocytes/metabolism ; Cells, Cultured ; Cell Proliferation
Czasopismo naukowe
Tytuł:
sFgl2 gene-modified MSCs regulate the differentiation of CD4 T cells in the treatment of autoimmune hepatitis.
Autorzy:
Ji W; Department of General Surgery, Tianjin Medical University General Hospital, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Wang W; Department of General Surgery, Tianjin Medical University Baodi Clinical College, Guangchuan Road, Baodi, Tianjin, 301800, China.
Li P; Department of General Surgery, Tianjin Medical University General Hospital, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Liu Y; Department of General Surgery, Tianjin Union Medical Center, Tianjin, China.; Tianjin Key Laboratory of General Surgery in Construction, Tianjin Union Medical Center, Tianjin, 300121, China.
Zhang B; Department of General Surgery, Tianjin Medical University General Hospital, No. 154, Anshan Road, Heping District, Tianjin, 300052, China.
Qi F; Department of General Surgery, Tianjin Medical University General Hospital, No. 154, Anshan Road, Heping District, Tianjin, 300052, China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2023 Nov 03; Vol. 14 (1), pp. 316. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Fibrinogen*/metabolism
Hepatitis, Autoimmune*/genetics
Hepatitis, Autoimmune*/therapy
Mesenchymal Stem Cells*/metabolism
T-Lymphocytes, Regulatory*
CD8-Positive T-Lymphocytes/metabolism ; Cell Differentiation ; Th1 Cells ; Th17 Cells ; Animals ; Mice
Czasopismo naukowe
Tytuł:
In vitro modelling of local gene therapy with IL-15/IL-15Rα and a PD-L1 antagonist in melanoma reveals an interplay between NK cells and CD4 T cells.
Autorzy:
Awad RM; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium. .
De Vlaeminck Y; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.
Meeus F; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.
Ertveldt T; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.
Zeven K; In Vivo Cellular and Molecular Imaging Laboratory, Department of Medical Imaging, Vrije Universiteit Brussel, 1090, Brussels, Belgium.
Ceuppens H; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.
Goyvaerts C; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.
Verdonck M; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.
Salguero G; Advanced Therapies Unit, Instituto Distrital de Ciencia Biotecnología e Innovación en Salud-IDCBIS, 111611, Bogotá, Colombia.
Raes G; Laboratory of Cellular and Molecular Immunology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, 1050, Brussels, Belgium.; Laboratory of Myeloid Cell Immunology, VIB Center for Inflammation Research, 1050, Brussels, Belgium.; Laboratory of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, 1050, Brussels, Belgium.
Devoogdt N; In Vivo Cellular and Molecular Imaging Laboratory, Department of Medical Imaging, Vrije Universiteit Brussel, 1090, Brussels, Belgium.
Breckpot K; Translational Oncology Research Center (TORC), Laboratory for Molecular and Cellular Therapy (LMCT), Department of Biomedical Sciences (BMWE), Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 03; Vol. 13 (1), pp. 18995. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Melanoma*/genetics
Melanoma*/therapy
Humans ; B7-H1 Antigen/genetics ; Interleukin-15/genetics ; Killer Cells, Natural ; Cytokines/pharmacology ; Genetic Therapy ; CD4-Positive T-Lymphocytes ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Metabolic and mitochondrial dysregulation in CD4+ T cells from HIV-positive women on combination anti-retroviral therapy.
Autorzy:
Akiso M; Department of Medical Microbiology & Immunology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.; KAVI-Institute of Clinical Research (KAVI-ICR), University of Nairobi, Nairobi, Kenya.
Ameka M; KAVI-Institute of Clinical Research (KAVI-ICR), University of Nairobi, Nairobi, Kenya.
Naidoo K; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Langat R; KAVI-Institute of Clinical Research (KAVI-ICR), University of Nairobi, Nairobi, Kenya.; Division of Surgical Outcomes and Precision Medicine Research, Department of Surgery, University of Minnesota Twin Cities, United States of America.
Kombo J; Department of Medical Microbiology & Immunology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.; KAVI-Institute of Clinical Research (KAVI-ICR), University of Nairobi, Nairobi, Kenya.
Sikuku D; Department of Medical Microbiology & Immunology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.
Ndung'u T; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Altfeld M; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Anzala O; Department of Medical Microbiology & Immunology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.; KAVI-Institute of Clinical Research (KAVI-ICR), University of Nairobi, Nairobi, Kenya.
Mureithi M; Department of Medical Microbiology & Immunology, Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya.; KAVI-Institute of Clinical Research (KAVI-ICR), University of Nairobi, Nairobi, Kenya.
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Źródło:
PloS one [PLoS One] 2023 Oct 10; Vol. 18 (10), pp. e0286436. Date of Electronic Publication: 2023 Oct 10 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*
HIV Infections*
Humans ; Female ; Leukocytes, Mononuclear/metabolism ; Fluorescein-5-isothiocyanate/metabolism ; CD8-Positive T-Lymphocytes ; Glucose/metabolism ; Antiretroviral Therapy, Highly Active
Czasopismo naukowe
Tytuł:
Early-life atomic-bomb irradiation accelerates immunological aging and elevates immune-related intracellular reactive oxygen species.
Autorzy:
Hayashi T; Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima, Japan.; Biosample Research Center, Radiation Effects Research Foundation, Hiroshima, Japan.
Kato N; Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan.
Furudoi K; Biosample Research Center, Radiation Effects Research Foundation, Hiroshima, Japan.
Hayashi I; Central Research Laboratory, Hiroshima University Faculty of Medicine Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Kyoizumi S; Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima, Japan.
Yoshida K; Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima, Japan.
Kusunoki Y; Department of Molecular Biosciences, Radiation Effects Research Foundation, Hiroshima, Japan.
Furukawa K; Biostatistics Center, Kurume University, Kurume, Japan.
Imaizumi M; Biosample Research Center, Radiation Effects Research Foundation, Hiroshima, Japan.; Department of Nagasaki Clinical Studies, Radiation Effects Research Foundation, Nagasaki, Japan.
Hida A; Department of Nagasaki Clinical Studies, Radiation Effects Research Foundation, Nagasaki, Japan.
Tanabe O; Biosample Research Center, Radiation Effects Research Foundation, Hiroshima, Japan.
Ohishi W; Department of Hiroshima Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan.
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Źródło:
Aging cell [Aging Cell] 2023 Oct; Vol. 22 (10), pp. e13940. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Nuclear Warfare*
Humans ; Reactive Oxygen Species ; Survivors ; Aging ; T-Lymphocyte Subsets ; Immunologic Memory ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Role of Regulatory T Cells and Their Potential Therapeutic Applications in Celiac Disease.
Autorzy:
Camarca A; Institute of Food Sciences, National Research Council-CNR, 83100 Avellino, Italy.
Rotondi Aufiero V; Institute of Food Sciences, National Research Council-CNR, 83100 Avellino, Italy.; Department of Medical Translational Sciences and European Laboratory for the Investigation of Food-Induced Diseases, University Federico II, 80138 Naples, Italy.
Mazzarella G; Institute of Food Sciences, National Research Council-CNR, 83100 Avellino, Italy.; Department of Medical Translational Sciences and European Laboratory for the Investigation of Food-Induced Diseases, University Federico II, 80138 Naples, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 22; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
T-Lymphocytes, Regulatory*
Celiac Disease*
Humans ; T-Lymphocyte Subsets ; CD4-Positive T-Lymphocytes ; Cytokines/metabolism ; Forkhead Transcription Factors/metabolism ; Interleukin-2 Receptor alpha Subunit/metabolism
Czasopismo naukowe
Tytuł:
CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells.
Autorzy:
Hinrichs AC; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Kruize AA; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Lafeber FPJG; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
Leavis HL; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
van Roon JAG; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, 3508 Utrecht, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 26; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Sjogren's Syndrome*
Humans ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Interleukins/metabolism ; Leukocytes, Mononuclear ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Receptors, CXCR5/metabolism ; T-Lymphocytes, Helper-Inducer
Czasopismo naukowe
Tytuł:
Transient regulatory-T-cell interruption promotes skin-resident memory T cells mediated tumor protection.
Autorzy:
Zhao S; Key Laboratory of Medical Molecular Virology of the Ministry of Health and Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Wu S; Key Laboratory of Medical Molecular Virology of the Ministry of Health and Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Jiang S; Key Laboratory of Medical Molecular Virology of the Ministry of Health and Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Zhou X; Key Laboratory of Medical Molecular Virology of the Ministry of Health and Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.; Department of Genetics, Yale University School of Medicine, New Haven, CT, 06520, USA.
Zhao G; Key Laboratory of Medical Molecular Virology of the Ministry of Health and Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.; Advaccine Biopharmaceutics (Suzhou) Co. Ltd., Suzhou, 215000, China.
Wang B; Key Laboratory of Medical Molecular Virology of the Ministry of Health and Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. .; Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, 200032, China. .; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, 200032, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 05; Vol. 13 (1), pp. 10898. Date of Electronic Publication: 2023 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes, Regulatory*
Neoplasms*
Humans ; Animals ; Mice ; Memory T Cells ; CD8-Positive T-Lymphocytes ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Enhancement of SARS-CoV-2 N Antigen-Specific T Cell Functionality by Modulating the Autophagy-Mediated Signal Pathway in Mice.
Autorzy:
Wen Z; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.
Yuan Y; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.
Zhao Y; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.
Wang H; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.
Han Z; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.
Li M; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.
Yuan J; Nanshan District Center for Disease Control and Prevention, Shenzhen 518000, China.
Sun C; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen 518107, China.; Key Laboratory of Tropical Disease Control (Sun Yat-Sen University), Ministry of Education, Guangzhou 510080, China.
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Źródło:
Viruses [Viruses] 2023 Jun 02; Vol. 15 (6). Date of Electronic Publication: 2023 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
COVID-19*/metabolism
Humans ; Animals ; Mice ; SARS-CoV-2 ; CD4-Positive T-Lymphocytes ; COVID-19 Vaccines/metabolism ; Autophagy ; Signal Transduction ; Antibodies, Viral
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
A Higher Dose of Staphylococcus aureus Enterotoxin B Led to More Th1 and Lower Th2/Th1 Ratio in Th Cells.
Autorzy:
Yuan J; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; China Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China.; College of Food Science & Technology, Nanchang University, Nanchang 330031, China.
Xu X; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; College of Food Science & Technology, Nanchang University, Nanchang 330031, China.
Wang Z; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; College of Food Science & Technology, Nanchang University, Nanchang 330031, China.
Tong P; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Meng X; China Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China.
Wu Y; China Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China.
Li X; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; College of Food Science & Technology, Nanchang University, Nanchang 330031, China.
Gao J; College of Food Science & Technology, Nanchang University, Nanchang 330031, China.
Chen H; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.; China Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China.
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Źródło:
Toxins [Toxins (Basel)] 2023 May 28; Vol. 15 (6). Date of Electronic Publication: 2023 May 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Staphylococcus aureus*/metabolism
T-Lymphocytes, Helper-Inducer*
Enterotoxins/metabolism ; CD4-Positive T-Lymphocytes/metabolism ; Superantigens ; Th1 Cells ; Th2 Cells ; Cytokines/metabolism
Czasopismo naukowe
Tytuł:
High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4 T cell arrest on the inflamed BBB under flow in vitro.
Autorzy:
Soldati S; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
Bär A; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
Vladymyrov M; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.
Glavin D; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
McGrath JL; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Gosselet F; Blood-Brain Barrier Laboratory, University of Artois, Lens, France.
Nishihara H; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.; Department of Neurotherapeutics, Yamaguchi University, Yamaguchi, Japan.
Goelz S; Biogen, Cambridge, MA, USA.
Engelhardt B; Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 May 23; Vol. 20 (1), pp. 123. Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Blood-Brain Barrier*
Humans ; Natalizumab ; Intercellular Adhesion Molecule-1 ; Integrin alpha4 ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
IL-10-Engineered Dendritic Cells Modulate Allogeneic CD8 T Cell Responses.
Autorzy:
Fortunato M; Mechanisms of Peripheral Tolerance Unit, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.; PhD Course in Molecular Medicine, University Vita-Salute San Raffaele, 20132 Milan, Italy.
Amodio G; Mechanisms of Peripheral Tolerance Unit, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Gregori S; Mechanisms of Peripheral Tolerance Unit, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 23; Vol. 24 (11). Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
Hematopoietic Stem Cell Transplantation*
Humans ; Interleukin-10/genetics ; T-Lymphocytes, Regulatory ; Dendritic Cells ; Lymphocyte Activation
Czasopismo naukowe
Tytuł:
Peripheral CD4 regulatory T cells are increased in patients with gastrointestinal cancer.
Autorzy:
Qiu J; Department of Oncology, Suzhou Science and Technology Town Hospital, Suzhou, Jiangsu, 215153, China. .
Shi W; Department of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.
Zhang J; Department of Pathology, Suzhou Science and Technology Town Hospital, Suzhou, Jiangsu, 215153, China.
Gao Q; Institute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.
Feng L; Department of Oncology, Suzhou Science and Technology Town Hospital, Suzhou, Jiangsu, 215153, China.
Zhuang Z; Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2023 May 20; Vol. 23 (1), pp. 168. Date of Electronic Publication: 2023 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
Stomach Neoplasms*
Humans ; Transforming Growth Factor beta1 ; Interleukin-10 ; CD4-Positive T-Lymphocytes ; Flow Cytometry ; Interleukin-2 Receptor alpha Subunit ; Forkhead Transcription Factors
Czasopismo naukowe
Tytuł:
Human CD4 cytotoxic T lymphocytes mediate potent tumor control in humanized immune system mice.
Autorzy:
Lin W; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Singh V; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Springer R; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Choonoo G; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Gupta N; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Patel A; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Frleta D; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Zhong J; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Owczarek T; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Decker C; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Macdonald L; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Murphy A; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Thurston G; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Mohrs M; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Ioffe E; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Lu YF; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Apr 25; Vol. 6 (1), pp. 447. Date of Electronic Publication: 2023 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Cytotoxic*
Neoplasms*/metabolism
Humans ; Mice ; Animals ; CD4-Positive T-Lymphocytes ; CD8-Positive T-Lymphocytes
Czasopismo naukowe

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