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Wyszukujesz frazę ""T-Lymphocytes"" wg kryterium: Temat


Tytuł:
An angel or a devil? Current view on the role of CD8 T cells in the pathogenesis of myasthenia gravis.
Autorzy:
Peng Y; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China. .; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China. .
Yang H; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen Q; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Jin H; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Xue YH; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Du MQ; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Liu S; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
Yao SY; Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, 412000, Hunan, China.; Department of Neurology, The Third Affiliated Hospital of Hunan University of Chinese Medicine, Zhuzhou, 412000, Hunan, China.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Feb 20; Vol. 22 (1), pp. 183. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
CD8-Positive T-Lymphocytes*
Myasthenia Gravis, Autoimmune, Experimental*/metabolism
Animals ; Humans ; T-Lymphocytes, Helper-Inducer/metabolism ; T-Lymphocytes, Regulatory ; Autoantigens/metabolism
Czasopismo naukowe
Tytuł:
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission.
Autorzy:
Baker KF; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. .; Musculoskeletal Unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. .
McDonald D; Flow Cytometry Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Hulme G; Flow Cytometry Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Hussain R; Genomics Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Coxhead J; Genomics Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Swan D; School of Medicine, University of Sunderland, Sunderland, UK.
Schulz AR; Deutsches Rheuma-Forschungszentrum Berlin, A Leibniz Institute, Berlin, Germany.
Mei HE; Deutsches Rheuma-Forschungszentrum Berlin, A Leibniz Institute, Berlin, Germany.
MacDonald L; School of Infection and Immunity, Glasgow University, Glasgow, UK.
Pratt AG; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Filby A; Flow Cytometry Core Facility, Newcastle University, Newcastle upon Tyne, UK.
Anderson AE; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Isaacs JD; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
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Źródło:
Nature communications [Nat Commun] 2024 Feb 05; Vol. 15 (1), pp. 1063. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*/metabolism
Arthritis, Rheumatoid*
Humans ; CD4-Positive T-Lymphocytes ; T-Lymphocyte Subsets ; T-Lymphocytes, Regulatory
Czasopismo naukowe
Tytuł:
Naturally occurring T cell mutations enhance engineered T cell therapies.
Autorzy:
Garcia J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Moonlight Bio, Seattle, WA, USA.
Daniels J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Moonlight Bio, Seattle, WA, USA.
Lee Y; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Zhu I; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Cheng K; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Liu Q; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Goodman D; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Burnett C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Law C; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Thienpont C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Alavi J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Azimi C; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Montgomery G; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Roybal KT; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA. .; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. .; Chan Zuckerberg Biohub, San Francisco, CA, USA. .; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. .; Department of Anesthesia, University of California, San Francisco, San Francisco, CA, USA. .; Gladstone-UCSF Institute for Genomic Immunology, San Francisco, CA, USA. .; UCSF Cell Design Institute, San Francisco, CA, USA. .
Choi J; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Center for Synthetic Biology, Northwestern University, Evanston, IL, USA. .; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7999), pp. 626-634. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Evolution, Molecular*
Immunotherapy, Adoptive*/methods
Lymphoma, T-Cell, Cutaneous*/genetics
Lymphoma, T-Cell, Cutaneous*/immunology
Lymphoma, T-Cell, Cutaneous*/pathology
Lymphoma, T-Cell, Cutaneous*/therapy
Mutation*
T-Lymphocytes*/immunology
T-Lymphocytes*/metabolism
T-Lymphocytes*/transplantation
Humans ; CARD Signaling Adaptor Proteins/genetics ; CARD Signaling Adaptor Proteins/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Cytokines/biosynthesis ; Cytokines/immunology ; Cytokines/metabolism ; Guanylate Cyclase/genetics ; Guanylate Cyclase/metabolism ; Phosphatidylinositol 3-Kinases ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
Autoreactive T cells target peripheral nerves in Guillain-Barré syndrome.
Autorzy:
Súkeníková L; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Mallone A; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Schreiner B; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Ripellino P; Department of Neurology, Neurocenter of Southern Switzerland EOC, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.
Nilsson J; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Stoffel M; Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.; Medical Faculty, University of Zurich, Zurich, Switzerland.
Ulbrich SE; Animal Physiology, Institute of Agricultural Sciences, ETH Zurich, Zurich, Switzerland.
Sallusto F; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.; Institute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.
Latorre D; Institute of Microbiology, ETH Zurich, Zurich, Switzerland. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7997), pp. 160-168. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*
CD8-Positive T-Lymphocytes*/immunology
CD8-Positive T-Lymphocytes*/pathology
Guillain-Barre Syndrome*/blood
Guillain-Barre Syndrome*/cerebrospinal fluid
Guillain-Barre Syndrome*/etiology
Guillain-Barre Syndrome*/immunology
Peripheral Nerves*/immunology
Peripheral Nerves*/pathology
Peripheral Nervous System Diseases*/complications
Peripheral Nervous System Diseases*/immunology
Peripheral Nervous System Diseases*/pathology
Th1 Cells*/immunology
Th1 Cells*/pathology
Humans ; Biopsy ; HLA-DR Antigens/immunology ; Immunodominant Epitopes/immunology ; Myelin Sheath/immunology ; Receptors, Antigen, T-Cell/immunology ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/pathology ; Immunologic Memory
Czasopismo naukowe
Tytuł:
Egg-sensitised infants have elevated CD4 effector memory T regulatory cells from birth.
Autorzy:
Gamez C; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.; School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Leffler J; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
Clark S; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
Corscadden K; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
Prescott SL; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.; School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.; Perth Children's Hospital, Nedlands, Western Australia, Australia.; The Nova Institute for Health, Baltimore, Maryland, USA.; Family and Community Medicine, University of Maryland, Baltimore, Maryland, USA.
Palmer DJ; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.; School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Strickland D; Telethon Kids Institute, The University of Western Australia, Nedlands, Western Australia, Australia.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2024 Jan; Vol. 54 (1), pp. 34-45. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Leukocytes, Mononuclear*
T-Lymphocytes*
Infant, Newborn ; Infant ; Humans ; Allergens ; CD4-Positive T-Lymphocytes ; Immunoglobulin E ; T-Lymphocytes, Regulatory
Czasopismo naukowe
Tytuł:
Hedgehog signalling in CD4 T helper cell polarisation.
Autorzy:
Hanna J; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, UK.
de la Roche M; University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, UK. Electronic address: .
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Źródło:
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2024 Mar; Vol. 168, pp. 106518. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Review; Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/cytology
CD4-Positive T-Lymphocytes*/metabolism
Hedgehog Proteins*/metabolism
Signal Transduction*
Cell Differentiation ; T-Lymphocytes, Helper-Inducer ; Transcription Factors/metabolism ; Humans ; Animals
Czasopismo naukowe
Tytuł:
Unveiling the immune system aging in single-cell resolution.
Autorzy:
Chan CL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China.; School of Biological Sciences, Kadoorie Biological Sciences Building, The University of Hong Kong, Pok Fu Lam Road, Hong Kong, SAR, China.
Sugimura R; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China.; Centre for Translational Stem Cell Biology, Rm1105, 11/F, 17W, Hong Kong Science and Technology Park, Shatin, N.T., Hong Kong SAR, China.
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Źródło:
Journal of leukocyte biology [J Leukoc Biol] 2024 Jan 05; Vol. 115 (1), pp. 16-18.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
T-Lymphocytes, Helper-Inducer*
Germinal Center*
Animals ; Mice ; B-Lymphocytes ; Lymph Nodes ; T-Lymphocytes, Regulatory ; Aging
Czasopismo naukowe
Tytuł:
Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function.
Autorzy:
Braverman EL; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
McQuaid MA; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Schuler H; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Qin M; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; School of Medicine, Tsinghua University, Beijing, China.
Hani S; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Hippen K; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Monlish DA; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Dobbs AK; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ramsey MJ; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Kemp F; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Wittmann C; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ramgopal A; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Brown H; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Blazar B; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Byersdorfer CA; Division of Blood and Marrow Transplant and Cellular Therapies, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105488. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Signal Transduction*
Gene Expression*/genetics
T-Lymphocytes*/cytology
T-Lymphocytes*/enzymology
T-Lymphocytes*/immunology
Humans ; Cytokines/metabolism ; Mitochondria/metabolism ; Th2 Cells/metabolism ; Memory T Cells/enzymology ; Glucose/metabolism ; CD4-Positive T-Lymphocytes/enzymology ; Cells, Cultured
Czasopismo naukowe
Tytuł:
TCR β chain repertoire characteristic between healthy human CD4+ and CD8+ T cells.
Autorzy:
Li G; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Chen Y; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Liu Y; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Gao Z; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Jia R; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Lv Z; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Li Y; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Wang Z; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
Han G; Beijing Institute of Basic Medical Sciences, Beijing 100850, China.
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Źródło:
Bioscience reports [Biosci Rep] 2024 Mar 29; Vol. 44 (3).
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Antigen, T-Cell, alpha-beta*/genetics
CD8-Positive T-Lymphocytes*
Humans ; Receptors, Antigen, T-Cell/genetics ; HLA Antigens ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development.
Autorzy:
Kim T; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Martínez-Bonet M; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Laboratory of Immune-regulation, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Wang Q; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Hackert N; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Rheumatology, Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; Institute for Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Sparks JA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Baglaenko Y; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Koh B; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Darbousset R; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Laza-Briviesca R; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Chen X; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Medical Center, Cincinnati, OH, USA.
Aguiar VRC; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Chiu DJ; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Westra HJ; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands.
Gutierrez-Arcelus M; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Weirauch MT; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Medical Center, Cincinnati, OH, USA.; Divisions of Human Genetics, Biomedical Informatics, and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Raychaudhuri S; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Rao DA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Nigrovic PA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. .; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Mar 09; Vol. 15 (1), pp. 2150. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*/metabolism
Arthritis, Rheumatoid*
Humans ; Inducible T-Cell Co-Stimulator Protein/metabolism ; CD28 Antigens/metabolism ; Alleles ; T-Lymphocytes, Helper-Inducer ; Chromosomal Proteins, Non-Histone/metabolism
Czasopismo naukowe
Tytuł:
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 T cells.
Autorzy:
Park JE; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Kim TS; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Zeng Y; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Mikolaj M; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Il Ahn J; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Alam MS; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Monnie CM; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15260, USA.
Shi V; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Zhou M; Protein Characterization Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Chun TW; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Maldarelli F; HIV Dynamics and Replication Program, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.
Narayan K; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Ahn J; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15260, USA.
Ashwell JD; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Strebel K; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Lee KS; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Mar 05; Vol. 15 (1), pp. 2017. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
HIV-1*
Humans ; Centrosome ; Carcinogenesis ; Cell Transformation, Neoplastic ; Aneuploidy ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Lysine acetyltransferase 6A maintains CD4 T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity.
Autorzy:
Fu JY; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Huang SJ; Laboratory of Oral Microbiota and Systematic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Wang BL; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Yin JH; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Chen CY; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Xu JB; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Chen YL; Laboratory of Oral Microbiota and Systematic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; Department of Neurosurgery, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Xu S; Laboratory of Oral Microbiota and Systematic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Hangzhou 310000, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Dong T; Laboratory of Oral Microbiota and Systematic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Zhou HN; College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China.
Ma XY; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Pu YP; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Li H; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Yang XJ; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Xie LS; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Wang ZJ; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Luo Q; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Shao YX; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Ye L; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Zong ZR; College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China.
Wei XD; College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China.
Xiao WW; College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China.
Niu ST; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Liu YM; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Xu HP; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Science, Westlake University, Hangzhou 310024, China.
Yu CQ; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China.
Duan SZ; Laboratory of Oral Microbiota and Systematic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Hangzhou 310000, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China. Electronic address: .
Zheng LY; Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai 200001, China. Electronic address: .
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Źródło:
Cell metabolism [Cell Metab] 2024 Mar 05; Vol. 36 (3), pp. 557-574.e10. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine Acetyltransferases*/genetics
Lysine Acetyltransferases*/metabolism
T-Lymphocytes*/metabolism
Animals ; Humans ; Mice ; Autoimmunity/genetics ; CD4-Positive T-Lymphocytes/metabolism ; Epigenesis, Genetic ; Glucose/metabolism ; Histone Acetyltransferases/genetics ; Histone Acetyltransferases/metabolism
Czasopismo naukowe
Tytuł:
CD8 T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs.
Autorzy:
Palmeri JR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Lax BM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Peters JM; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
Duhamel L; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Stinson JA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Santollani L; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Lutz EA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Pinney W 3rd; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.
Bryson BD; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
Dane Wittrup K; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA. .; Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA. .; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Mar 01; Vol. 15 (1), pp. 1900. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*
Neoplasms*/immunology
Neoplasms*/therapy
T-Lymphocytes, Regulatory*
Animals ; Mice ; Antibodies ; CD8-Positive T-Lymphocytes ; Immunotherapy ; Tumor Microenvironment ; 4-1BB Ligand/immunology
Czasopismo naukowe
Tytuł:
Absence of Stat1 in donor CD4+ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.
Autorzy:
Ma H
Lu C
Ziegler J
Liu A
Sepulveda A
Okada H
Lentzsch S
Mapara MY
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2024 Mar 01; Vol. 134 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Graft vs Host Disease*
Mice ; Animals ; T-Lymphocytes, Regulatory ; Mice, Inbred C57BL ; Mice, Inbred BALB C ; STAT1 Transcription Factor/genetics
Czasopismo naukowe
Tytuł:
Gel-mediated recruitment of conventional type 1 dendritic cells potentiates the therapeutic effects of radiotherapy.
Autorzy:
Wu Y; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Li Q; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Yan Y; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Hao Y; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Wang C; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Liu B; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Zhu Y; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China.
Liu Z; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China. Electronic address: .
Feng L; Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China. Electronic address: .
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Źródło:
Biomaterials [Biomaterials] 2024 Mar; Vol. 305, pp. 122470. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
Cross-Priming*
T-Lymphocytes, Cytotoxic ; Dendritic Cells ; Hydrogels/pharmacology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs.
Autorzy:
English K; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; VIB-UGent Center for Inflammation Research, Ghent, Belgium.
Kwan R; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Holz LE; Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
McGuffog C; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Krol JMM; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands.
Kempe D; EMBL Australia, Single Molecule Science node, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
Kaisho T; Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Heath WR; Department of Microbiology and Immunology at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Lisowski L; Children's Medical Research Institute, Translational Vectorology Research Unit, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warsaw, Poland.
Biro M; EMBL Australia, Single Molecule Science node, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
McCaughan GW; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Bowen DG; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia. .
Bertolino P; Centenary Institute and The University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia. .
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Źródło:
Nature communications [Nat Commun] 2024 Feb 10; Vol. 15 (1), pp. 1261. Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/immunology
Liver*/immunology
Lymphoid Tissue*/immunology
Antigens ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/immunology ; Humans
Czasopismo naukowe
Tytuł:
T Cell Responses in Pregnant Women Who Received mRNA-Based Vaccination to Prevent COVID-19 Revealed Unknown Exposure to the Natural Infection and Numerous SARS-CoV-2-Specific CD4- CD8- Double Negative T Cells and Regulatory T Cells.
Autorzy:
Chambers CD; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Song J; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
da Silva Antunes R; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Sette A; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Franco A; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
COVID-19*/prevention & control
Pregnancy ; Female ; Humans ; SARS-CoV-2 ; Pregnant Women ; COVID-19 Vaccines ; Vaccination ; CD8-Positive T-Lymphocytes ; Peptides ; Antibodies, Viral
Czasopismo naukowe
Tytuł:
T follicular helper cells expansion in transplant recipients correlates with graft infiltration and adverse outcomes.
Autorzy:
Désy O; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Béland S; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Thivierge MP; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Marcoux M; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Desgagnés JS; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Bouchard-Boivin F; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Gama A; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Riopel J; Pathology Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
Latulippe E; Pathology Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
De Serres SA; Transplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Faculty of Medicine, Laval University, Québec, QC, Canada.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Feb 07; Vol. 15, pp. 1275933. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Helper-Inducer*
T Follicular Helper Cells*
Humans ; Transplant Recipients ; Leukocytes, Mononuclear ; CD4-Positive T-Lymphocytes ; Antilymphocyte Serum
Czasopismo naukowe
Tytuł:
FSTL3 promotes tumor immune evasion and attenuates response to anti-PD1 therapy by stabilizing c-Myc in colorectal cancer.
Autorzy:
Li H; Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Zheng N; General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.; General Clinical Research Center, Nanjing First Hospital, China Pharmaceutical University, Nanjing, Jiangsu, China.
Guo A; General Clinical Research Center, Nanjing First Hospital, China Pharmaceutical University, Nanjing, Jiangsu, China.
Tang W; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, Jiangsu, China.
Li M; General Clinical Research Center, Nanjing First Hospital, China Pharmaceutical University, Nanjing, Jiangsu, China.
Cao Y; General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Ma X; General Clinical Research Center, Nanjing First Hospital, China Pharmaceutical University, Nanjing, Jiangsu, China.
Cao H; Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. .
Ma Y; Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. .
Wang H; Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. whj_.
Zhao S; General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. .; General Clinical Research Center, Nanjing First Hospital, China Pharmaceutical University, Nanjing, Jiangsu, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2024 Feb 01; Vol. 15 (2), pp. 107. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Humans ; Tumor Escape ; Immunotherapy/methods ; T-Lymphocytes, Regulatory ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Re-centauring T cell antigen discovery around CD4 T cells.
Autorzy:
Smith BE; Program in Immunology, Harvard Medical School, Boston, MA, USA; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA.
Chan AO; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Birnbaum ME; Koch Institute for Integrative Cancer Research, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: .
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Źródło:
Cell reports methods [Cell Rep Methods] 2024 Jan 22; Vol. 4 (1), pp. 100694.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Autoimmunity*
Epitopes, T-Lymphocyte ; CD4-Positive T-Lymphocytes
Czasopismo naukowe

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