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Wyszukujesz frazę ""TGF"" wg kryterium: Temat


Tytuł:
The TGF-β Family in Glioblastoma.
Autorzy:
Golán-Cancela I; Department of Medical Biochemistry and Microbiology, Biomedical Center, Uppsala University, SE-75123 Uppsala, Sweden.
Caja L; Department of Medical Biochemistry and Microbiology, Biomedical Center, Uppsala University, SE-75123 Uppsala, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 15; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain Neoplasms*/genetics
Glioblastoma*/genetics
TGF-beta Superfamily Proteins*/genetics
Humans ; Carcinogenesis ; Cell Differentiation ; Transforming Growth Factor beta ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
In vivo identification of angle dysgenesis and its relation to genetic markers associated with glaucoma using artificial intelligence.
Autorzy:
Gupta V; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Birla S; Translational Bioinformatics Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Jawaharlal Nehru University, New Delhi, India.
Varshney T; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Somarajan BI; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Gupta S; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Gupta M; Department of Biomedical Engineering Technical University of Munich, Munich, Germany.
Panigrahi A; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Singh A; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Gupta D; Translational Bioinformatics Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Jawaharlal Nehru University, New Delhi, India.
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Źródło:
Indian journal of ophthalmology [Indian J Ophthalmol] 2024 Mar 01; Vol. 72 (3), pp. 339-346. Date of Electronic Publication: 2023 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Glaucoma, Open-Angle*/diagnosis
Glaucoma, Open-Angle*/genetics
Glaucoma*/diagnosis
Adult ; Humans ; Artificial Intelligence ; Genetic Markers ; Intraocular Pressure ; Trabecular Meshwork ; Tomography, Optical Coherence/methods ; Latent TGF-beta Binding Proteins
Czasopismo naukowe
Tytuł:
Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury.
Autorzy:
Neikirk K; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Ume AC; Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio, USA.
Prasad P; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.; Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
Marshall AG; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Rockwood J; Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio, USA.
Wenegieme TY; Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio, USA.
McMichael KE; Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio, USA.
McReynolds MR; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.; Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
Williams CR; Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio, USA.
Hinton A Jr; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
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Źródło:
Aging cell [Aging Cell] 2023 Dec; Vol. 22 (12), pp. e14019. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acute Kidney Injury*
Humans ; Latent TGF-beta Binding Proteins/metabolism ; Kidney/metabolism ; Transforming Growth Factor beta/metabolism ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł:
Two novel compound heterozygous variants of LTBP4 in a Chinese infant with cutis laxa type IC and a review of the related literature.
Autorzy:
Zhang Q; Laboratory of Genetic and Metabolism, Department of Paediatric Endocrine and Metabolism, Maternal and Child Health Hospital of Guangxi, Nanning, 530000, China. .
Qin Z; Laboratory of Genetic and Metabolism, Department of Paediatric Endocrine and Metabolism, Maternal and Child Health Hospital of Guangxi, Nanning, 530000, China.
Yi S; Laboratory of Genetic and Metabolism, Department of Paediatric Endocrine and Metabolism, Maternal and Child Health Hospital of Guangxi, Nanning, 530000, China.
Wei H; Laboratory of Genetic and Metabolism, Department of Paediatric Endocrine and Metabolism, Maternal and Child Health Hospital of Guangxi, Nanning, 530000, China.
Zhou XZ; Laboratory of Genetic and Metabolism, Department of Paediatric Endocrine and Metabolism, Maternal and Child Health Hospital of Guangxi, Nanning, 530000, China.
Su J; Laboratory of Genetic and Metabolism, Department of Paediatric Endocrine and Metabolism, Maternal and Child Health Hospital of Guangxi, Nanning, 530000, China.
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Źródło:
BMC medical genomics [BMC Med Genomics] 2020 Dec 10; Vol. 13 (1), pp. 183. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Frameshift Mutation*
Abnormalities, Multiple/*genetics
Cutis Laxa/*genetics
Latent TGF-beta Binding Proteins/*genetics
Asian People/genetics ; Chromosomes, Human, Pair 19/genetics ; Codon, Nonsense ; Cutis Laxa/ethnology ; Female ; Heterozygote ; Humans ; Infant ; Infant, Newborn ; Latent TGF-beta Binding Proteins/chemistry ; Latent TGF-beta Binding Proteins/physiology ; Models, Molecular ; Open Reading Frames/genetics ; Pedigree ; Protein Conformation ; Pulmonary Emphysema/diagnostic imaging ; Pulmonary Emphysema/genetics ; Exome Sequencing
SCR Disease Name:
Cutis Laxa, Autosomal Recessive, Type I
Czasopismo naukowe
Tytuł:
Association of polymorphisms rs2303729, rs10880, and rs1131620 of LTBP4 with sarcopenia in elderly patients with type 2 diabetes mellitus.
Autorzy:
Ibarra-Tapia IY; Subdirección de Enseñanza e Investigación, Centro Médico Nacional '20 de Noviembre', Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, México.
Juárez-Sandoval A; Subdirección de Enseñanza e Investigación, Centro Médico Nacional '20 de Noviembre', Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, México.
Pérez IT; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México.
Cano-Martínez LJ; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México.
Sánchez-García S; Unidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento. Instituto Mexicano del Seguro Social, Ciudad de México, México.
Ruiz-Batalla JM; Unidad de Medicina Familiar No. 1, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Aroche-Reyes IA; Unidad de Medicina Familiar No. 1, Instituto Mexicano del Seguro Social, Ciudad de México, México.
García S; Subdirección de Enseñanza e Investigación, Centro Médico Nacional '20 de Noviembre', Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, México.
Canto P; Unidad de Investigación en Obesidad, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, México.
Mejía DR; Unidad Médica de Alta Especialidad de Traumatología, Instituto Mexicano del Seguro Social, Ortopedia y Rehabilitación 'Dr. Victorio de la Fuente Narváez', Ciudad de México, México.
Coral-Vázquez RM; Subdirección de Enseñanza e Investigación, Centro Médico Nacional '20 de Noviembre', Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, México.; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México.
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Źródło:
Annals of human biology [Ann Hum Biol] 2022 Dec; Vol. 49 (7-8), pp. 311-316. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Sarcopenia*/genetics
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/genetics
Muscular Dystrophy, Duchenne*/genetics
Muscular Dystrophy, Duchenne*/metabolism
Humans ; Aged ; Latent TGF-beta Binding Proteins/genetics ; Latent TGF-beta Binding Proteins/metabolism ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
LTBP1 plays a potential bridge between depressive disorder and glioblastoma.
Autorzy:
Fu X; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Xiangshanyikesong 50#, HaiDian District, Beijing, 100093, China.; Capital Medical University, Beijing, People's Republic of China.
Zhang P; Beijing Institute of Technology, Beijing, China.
Song H; Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.
Wu C; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Xiangshanyikesong 50#, HaiDian District, Beijing, 100093, China.
Li S; Beijing Institute of Technology, Beijing, China.
Li S; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Xiangshanyikesong 50#, HaiDian District, Beijing, 100093, China. .
Yan C; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Xiangshanyikesong 50#, HaiDian District, Beijing, 100093, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2020 Oct 15; Vol. 18 (1), pp. 391. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms*/genetics
Depressive Disorder*/genetics
Glioblastoma*/genetics
Latent TGF-beta Binding Proteins*/genetics
Gene Expression Regulation, Neoplastic ; Humans ; Protein Interaction Maps
Czasopismo naukowe
Tytuł:
LTBP2 knockdown by siRNA reverses myocardial oxidative stress injury, fibrosis and remodelling during dilated cardiomyopathy.
Autorzy:
Pang XF; Department of Cardiovascular, The First Hospital of China Medical University, Shenyang, China.
Lin X; Department of Cardiovascular, Peking Union Medical College Hospital, Beijing, China.
Du JJ; Department of Cardiovascular, The First Hospital of China Medical University, Shenyang, China.
Zeng DY; Department of Cardiovascular, The First Hospital of China Medical University, Shenyang, China.
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Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2020 Mar; Vol. 228 (3), pp. e13377. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiomyopathy, Dilated/*metabolism
Fibrosis/*prevention & control
Latent TGF-beta Binding Proteins/*metabolism
Myocardial Ischemia/*prevention & control
Animals ; Cardiomyopathy, Dilated/genetics ; Cardiomyopathy, Dilated/pathology ; Cells, Cultured ; Disease Models, Animal ; Fibrosis/etiology ; Fibrosis/metabolism ; Fibrosis/pathology ; Gene Knockdown Techniques ; Hemodynamics ; Latent TGF-beta Binding Proteins/antagonists & inhibitors ; Latent TGF-beta Binding Proteins/genetics ; Male ; Myocardial Ischemia/etiology ; Myocardial Ischemia/metabolism ; Myocardial Ischemia/pathology ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Oxidative Stress/physiology ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/genetics ; Rats ; Signal Transduction ; Vascular Remodeling
Czasopismo naukowe
Tytuł:
Identification of Immune Infiltration and the Potential Biomarkers in Diabetic Peripheral Neuropathy through Bioinformatics and Machine Learning Methods.
Autorzy:
Li W; Department of Hand and Foot Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China.
Guo J; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, China.
Chen J; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, China.
Yao H; Department of Hand and Foot Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China.
Mao R; Department of Hand and Foot Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China.
Li C; Department of Hand and Foot Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China.
Zhang G; Department of Hand and Foot Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China.
Chen Z; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, China.
Xu X; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, China.
Wang C; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, China.
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Źródło:
Biomolecules [Biomolecules] 2022 Dec 26; Vol. 13 (1). Date of Electronic Publication: 2022 Dec 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetic Neuropathies*/diagnosis
Diabetic Neuropathies*/genetics
Diabetes Mellitus*
Humans ; Genes, Regulator ; Transcription Factors ; Computational Biology ; Biomarkers ; Machine Learning ; Latent TGF-beta Binding Proteins ; Membrane Glycoproteins
Czasopismo naukowe
Tytuł:
LRRC33 is a novel binding and potential regulating protein of TGF-β1 function in human acute myeloid leukemia cells.
Autorzy:
Ma W; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Qin Y; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States of America.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Chapuy B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America.
Lu C; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Oct 10; Vol. 14 (10), pp. e0213482. Date of Electronic Publication: 2019 Oct 10 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Latent TGF-beta Binding Proteins/*metabolism
Leukemia, Myeloid, Acute/*metabolism
Neoplasm Proteins/*metabolism
Transforming Growth Factor beta1/*metabolism
Cell Line, Tumor ; Drug Delivery Systems ; Humans ; Latent TGF-beta Binding Proteins/genetics ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Neoplasm Proteins/genetics ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Neoplasm/genetics ; RNA, Neoplasm/metabolism ; Transforming Growth Factor beta1/genetics
Czasopismo naukowe
Tytuł:
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Autorzy:
Rauf B; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Maumenee 809, Baltimore, MD, 21287, USA.; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Khan SY; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Maumenee 809, Baltimore, MD, 21287, USA.
Jiao X; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Irum B; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Maumenee 809, Baltimore, MD, 21287, USA.; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Ashfaq R; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Zehra M; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Khan AA; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Naeem MA; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Shahzad M; Jinnah Burn and Reconstructive Surgery Centre, Allama Iqbal Medical College, University of Health Sciences, Lahore, 54550, Pakistan.
Riazuddin S; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.; Jinnah Burn and Reconstructive Surgery Centre, Allama Iqbal Medical College, University of Health Sciences, Lahore, 54550, Pakistan.
Hejtmancik JF; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Riazuddin SA; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Maumenee 809, Baltimore, MD, 21287, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 14; Vol. 12 (1), pp. 17218. Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Exome*/genetics
Glaucoma*/congenital
Glaucoma*/genetics
Consanguinity ; Humans ; Latent TGF-beta Binding Proteins/genetics ; Mutation ; Exome Sequencing
Czasopismo naukowe
Tytuł:
LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62-Keap1-Nrf2 Pathway.
Autorzy:
Wang T; Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Guangxi Clinical Research Center for Colorectal Cancer, Nanning, 530021 Guangxi, China.
Zhou Z; Department of Cancer Prevention and Control, Guangxi Medical University Cancer Hospital, Nanning, 530021 Guangxi, China.
Wang C; Department of College of Pharmacy, Guangxi Medical University, Nanning, 530021 Guangxi, China.
Qin Y; Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Guangxi Clinical Research Center for Colorectal Cancer, Nanning, 530021 Guangxi, China.
Wu L; Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Guangxi Clinical Research Center for Colorectal Cancer, Nanning, 530021 Guangxi, China.
Hu B; Department of Research, Guangxi Medical University Cancer Hospital, Nanning, 530021 Guangxi, China.
Jin Q; Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Guangxi Clinical Research Center for Colorectal Cancer, Nanning, 530021 Guangxi, China.
Wei W; Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Guangxi Clinical Research Center for Colorectal Cancer, Nanning, 530021 Guangxi, China.
Huang M; Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Guangxi Clinical Research Center for Colorectal Cancer, Nanning, 530021 Guangxi, China.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Aug 04; Vol. 2022, pp. 6532253. Date of Electronic Publication: 2022 Aug 04 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*/genetics
Ferroptosis*/physiology
Kelch-Like ECH-Associated Protein 1*/genetics
Kelch-Like ECH-Associated Protein 1*/metabolism
NF-E2-Related Factor 2*/genetics
NF-E2-Related Factor 2*/metabolism
Stomach Neoplasms*/genetics
Humans ; Latent TGF-beta Binding Proteins/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Cancer-associated fibroblasts: a versatile mediator in tumor progression, metastasis, and targeted therapy
Autorzy:
Guo, Tianchen
Xu, JunfenAff2, IDs10555024101867_cor2
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Źródło:
Cancer and Metastasis Reviews. :1-22
Czasopismo naukowe
Tytuł:
Downregulation of Ubiquitin-Specific Protease 15 (USP15) Does Not Provide Therapeutic Benefit in Experimental Mesial Temporal Lobe Epilepsy
Autorzy:
Häussler, UteAff1, Aff2, IDs12035023036922_cor1
Neres, João
Vandenplas, Catherine
Eykens, Caroline
Kadiu, Irena
Schramm, Carolin
Fleurance, Renaud
Stanley, Phil
Godard, Patrice
de Mot, Laurane
van Eyll, Jonathan
Knobeloch, Klaus-PeterAff5, Aff6, IDs12035023036922_cor12
Haas, Carola A.Aff1, Aff2, Aff7, Aff8
Dedeurwaerdere, StefanieAff3, IDs12035023036922_cor14
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Źródło:
Molecular Neurobiology. 61(4):2367-2389
Czasopismo naukowe

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