Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""TNF-Related Apoptosis-Inducing Ligand"" wg kryterium: Temat


Tytuł:
TRAIL-R Deficient Mice Are Protected from Neurotoxic Effects of Amyloid-β.
Autorzy:
Di Benedetto G; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Burgaletto C; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Serapide MF; Section of Physiology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Caltabiano R; Section of Anatomic Pathology, Department of Medical and Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', University of Catania, 95123 Catania, Italy.
Munafò A; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Bellanca CM; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Di Mauro R; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.; Clinical Toxicology Unit, University Hospital of Catania, 95123 Catania, Italy.
Bernardini R; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.; Clinical Toxicology Unit, University Hospital of Catania, 95123 Catania, Italy.
Cantarella G; Section of Pharmacology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 01; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 01.
Typ publikacji:
Journal Article
MeSH Terms:
Neurotoxicity Syndromes*
Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics
Tumor Necrosis Factor-alpha*/metabolism
Amyloid beta-Peptides/metabolism ; Animals ; Caspases/metabolism ; Cyclooxygenase 2/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Inflammation ; Mice ; Mice, Knockout ; Proto-Oncogene Proteins c-akt/metabolism ; Tumor Suppressor Protein p53
Czasopismo naukowe
Tytuł:
Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells.
Autorzy:
Tyciakova S; Cancer Research Institute, Biomedical Research Center of Slovak Academy of Sciences, Dubravska cesta 9, 845 05, Bratislava, Slovakia. .
Valova V; Cancer Research Institute, Biomedical Research Center of Slovak Academy of Sciences, Dubravska cesta 9, 845 05, Bratislava, Slovakia.; Department of Genetics, Faculty of Natural Sciences, Comenius University, Mlynská dolina, Ilkovicova 6, 842 15, Bratislava, Slovakia.
Svitkova B; Cancer Research Institute, Biomedical Research Center of Slovak Academy of Sciences, Dubravska cesta 9, 845 05, Bratislava, Slovakia.
Matuskova M; Cancer Research Institute, Biomedical Research Center of Slovak Academy of Sciences, Dubravska cesta 9, 845 05, Bratislava, Slovakia.
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2021 May 06; Vol. 21 (1), pp. 507. Date of Electronic Publication: 2021 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*physiology
Melanoma/*pathology
Mitochondria/*physiology
Tumor Necrosis Factor-alpha/*physiology
Aldehyde Dehydrogenase/metabolism ; Cell Line, Tumor ; Cellular Senescence ; Colorectal Neoplasms/pathology ; Humans ; Interleukin-6/genetics ; Receptors, Tumor Necrosis Factor, Type I/physiology ; Receptors, Tumor Necrosis Factor, Type II/physiology ; TNF-Related Apoptosis-Inducing Ligand/genetics
Czasopismo naukowe
Tytuł:
Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL, and interleukin-12.
Autorzy:
Altwaijry N; a Strathclyde Institute of Pharmacy and Biomedical Sciences , University of Strathclyde , Glasgow , UK.
Somani S; a Strathclyde Institute of Pharmacy and Biomedical Sciences , University of Strathclyde , Glasgow , UK.
Parkinson JA; b Department of Pure and Applied Chemistry , University of Strathclyde , Glasgow , UK.
Tate RJ; a Strathclyde Institute of Pharmacy and Biomedical Sciences , University of Strathclyde , Glasgow , UK.
Keating P; b Department of Pure and Applied Chemistry , University of Strathclyde , Glasgow , UK.
Warzecha M; a Strathclyde Institute of Pharmacy and Biomedical Sciences , University of Strathclyde , Glasgow , UK.
Mackenzie GR; a Strathclyde Institute of Pharmacy and Biomedical Sciences , University of Strathclyde , Glasgow , UK.
Leung HY; c Cancer Research UK Beatson Institute , Glasgow , UK.
Dufès C; a Strathclyde Institute of Pharmacy and Biomedical Sciences , University of Strathclyde , Glasgow , UK.
Pokaż więcej
Źródło:
Drug delivery [Drug Deliv] 2018 Nov; Vol. 25 (1), pp. 679-689.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-12/*administration & dosage
Lactoferrin/*administration & dosage
Polypropylenes/*administration & dosage
Prostatic Neoplasms/*therapy
TNF-Related Apoptosis-Inducing Ligand/*administration & dosage
Tumor Necrosis Factor-alpha/*administration & dosage
Administration, Intravenous ; Animals ; Cell Line, Tumor ; Genetic Therapy/methods ; Humans ; Interleukin-12/genetics ; Male ; Mice ; Mice, Inbred BALB C ; Prostatic Neoplasms/genetics ; TNF-Related Apoptosis-Inducing Ligand/genetics ; Tumor Necrosis Factor-alpha/genetics ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł:
Lipid Nanoparticles Decorated with TNF-Related Aptosis-Inducing Ligand (TRAIL) Are More Cytotoxic than Soluble Recombinant TRAIL in Sarcoma.
Autorzy:
Gallego-Lleyda A; Departamento de Bioquímica, Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain. .; Instituto de Investigación Sanitaria de Aragón (ISS), 50009 Zaragoza, Spain. .
De Miguel D; Departamento de Bioquímica, Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain. diego_.; Cell Death, Cancer and Inflammation, University College of London, London WC1E 6BT, UK. diego_.
Anel A; Departamento de Bioquímica, Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain. .; Instituto de Investigación Sanitaria de Aragón (ISS), 50009 Zaragoza, Spain. .
Martinez-Lostao L; Instituto de Investigación Sanitaria de Aragón (ISS), 50009 Zaragoza, Spain. .; Servicio de Inmunología, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, Spain. .; Departamento de Microbiología, Medicina Preventiva y Salud Pública, Universidad de Zaragoza, 50009 Zaragoza, Spain. .; Instituto de Nanociencia de Aragón, 50009 Zaragoza, Spain. .
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 May 13; Vol. 19 (5). Date of Electronic Publication: 2018 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Lipids*
Nanoparticles*
Sarcoma/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Antineoplastic Agents/pharmacology ; Caspases/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Humans ; Recombinant Proteins ; TNF-Related Apoptosis-Inducing Ligand/pharmacology
Czasopismo naukowe
Tytuł:
TRAIL inhibits oxidative stress in human aortic endothelial cells exposed to pro-inflammatory stimuli.
Autorzy:
Forde H; Department of Endocrinology, Beaumont Hospital and RCSI medical school, Beaumont, Dublin 9, Ireland.; School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Harper E; School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Rochfort KD; School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Wallace RG; School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Davenport C; School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Smith D; Department of Endocrinology, Beaumont Hospital and RCSI medical school, Beaumont, Dublin 9, Ireland.
Cummins PM; School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Pokaż więcej
Źródło:
Physiological reports [Physiol Rep] 2020 Oct; Vol. 8 (20), pp. e14612.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Stress*
Endothelial Cells/*drug effects
Endothelium, Vascular/*drug effects
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Tumor Necrosis Factor-alpha/*pharmacology
Aorta/cytology ; Cells, Cultured ; Endothelial Cells/metabolism ; Endothelium, Vascular/cytology ; Endothelium, Vascular/metabolism ; Female ; Glucose/pharmacology ; Humans ; Middle Aged ; Stress, Mechanical
Czasopismo naukowe
Tytuł:
Fas-FasL interaction in cytotoxic T cell-mediated vitiligo: The role of lesional expression of tumor necrosis factor-α and interferon-γ in Fas-mediated melanocyte apoptosis.
Autorzy:
Jimbo H; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Nagai H; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Fujiwara S; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Shimoura N; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Nishigori C; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Pokaż więcej
Źródło:
Experimental dermatology [Exp Dermatol] 2020 Jan; Vol. 29 (1), pp. 61-70. Date of Electronic Publication: 2019 Nov 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fas Ligand Protein/*metabolism
Interferon-gamma/*metabolism
T-Lymphocytes, Cytotoxic/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Vitiligo/*metabolism
fas Receptor/*metabolism
Animals ; Apoptosis/genetics ; Baculoviral IAP Repeat-Containing 3 Protein/genetics ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; Cells, Cultured ; Fas Ligand Protein/genetics ; Female ; Gene Silencing ; Humans ; Interferon-gamma/pharmacology ; Male ; Melanocytes/physiology ; Metabolic Networks and Pathways ; Mice ; Middle Aged ; Myeloid Cell Leukemia Sequence 1 Protein/genetics ; RNA, Messenger/metabolism ; TNF-Related Apoptosis-Inducing Ligand ; Tumor Necrosis Factor-alpha/pharmacology ; Up-Regulation/drug effects ; Vitiligo/genetics ; Vitiligo/immunology ; fas Receptor/genetics
Czasopismo naukowe
Tytuł:
TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin.
Autorzy:
Hodges AL; Department of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciences, Albany, NY 12208, USA.
Kempen CG; Department of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciences, Albany, NY 12208, USA.
McCaig WD; Department of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciences, Albany, NY 12208, USA.
Parker CA; Department of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciences, Albany, NY 12208, USA.
Mantis NJ; Division of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA. .
LaRocca TJ; Department of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciences, Albany, NY 12208, USA. .
Pokaż więcej
Źródło:
Toxins [Toxins (Basel)] 2019 Aug 01; Vol. 11 (8). Date of Electronic Publication: 2019 Aug 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Fas Ligand Protein/*toxicity
Ricin/*toxicity
TNF-Related Apoptosis-Inducing Ligand/*toxicity
Tumor Necrosis Factor-alpha/*toxicity
A549 Cells ; Amino Acid Chloromethyl Ketones/pharmacology ; Caspase Inhibitors/pharmacology ; Cell Death/drug effects ; Humans ; Lung/cytology ; U937 Cells
Czasopismo naukowe
Tytuł:
HPV-Mediated Resistance to TNF and TRAIL Is Characterized by Global Alterations in Apoptosis Regulatory Factors, Dysregulation of Death Receptors, and Induction of ROS/RNS.
Autorzy:
Cabeça TK; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil. .
de Mello Abreu A; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil. .
Andrette R; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil. .
de Souza Lino V; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil. vanesca_.
Morale MG; Laboratório de Inovação em Câncer, Centro de Investigação Translacional em Oncologia (LIM24), Instituto do Câncer do Estado de São Paulo (ICESP), 01246-000 São Paulo, Brazil. .; Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de São Paulo (USP), 01246-903 São Paulo, Brazil. .
Aguayo F; Department of Basic and Clinical Oncology, Faculty of Medicine, University of Chile, 8389100 Santiago, Chile. .; Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile, 8389100 Santiago, Chile. .
Termini L; Laboratório de Inovação em Câncer, Centro de Investigação Translacional em Oncologia (LIM24), Instituto do Câncer do Estado de São Paulo (ICESP), 01246-000 São Paulo, Brazil. .
Villa LL; Laboratório de Inovação em Câncer, Centro de Investigação Translacional em Oncologia (LIM24), Instituto do Câncer do Estado de São Paulo (ICESP), 01246-000 São Paulo, Brazil. .; Departamento de Radiologia e Oncologia, Faculdade de Medicina da Universidade de São Paulo (USP), 01246-903 São Paulo, Brazil. .
Lepique AP; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil. .
Boccardo E; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil. .
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jan 08; Vol. 20 (1). Date of Electronic Publication: 2019 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins/*metabolism
Drug Resistance, Neoplasm/*drug effects
Papillomaviridae/*physiology
Reactive Nitrogen Species/*metabolism
Reactive Oxygen Species/*metabolism
Receptors, Death Domain/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Tumor Necrosis Factor-alpha/*pharmacology
Down-Regulation/drug effects ; HeLa Cells ; Humans ; Inflammation Mediators/metabolism ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Keratinocytes/virology ; Membrane Potential, Mitochondrial/drug effects ; NF-kappa B/metabolism ; Oncogenes ; Papillomaviridae/drug effects ; Papillomaviridae/genetics ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Signal Transduction/drug effects ; Viral Proteins/genetics ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł:
The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells.
Autorzy:
Tang H; Institute of Biochemistry, College of Life Sciences, Zijingang campus, Room 345, Zhejiang University, Hangzhou, PR China.
Qin Y
Li J
Gong X
Pokaż więcej
Źródło:
BMC biology [BMC Biol] 2011 Mar 19; Vol. 9, pp. 18. Date of Electronic Publication: 2011 Mar 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt/*metabolism
Recombinant Fusion Proteins/*pharmacology
Superoxide Dismutase/*pharmacology
Superoxides/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Tumor Necrosis Factor-alpha/*pharmacology
Apoptosis/drug effects ; HL-60 Cells ; Humans ; Hydrogen Peroxide/metabolism ; K562 Cells ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Tytuł:
17β-Estradiol inhibits TNF-α-induced proliferation and migration of vascular smooth muscle cells via suppression of TRAIL.
Autorzy:
Li H; a Department of Anesthesiology , Zhujiang Hospital of Southern Medical University , Guangzhou, Guangdong Province , China .; b Guangzhou First People's Hospital , Guangzhou, Guangdong Province , China , and.
Cheng Y; b Guangzhou First People's Hospital , Guangzhou, Guangdong Province , China , and.
Simoncini T; c Molecular and Cellular Gynecological Endocrinology Laboratory (MCGEL), Department of Reproductive Medicine and Child Development, University of Pisa , Pisa , Italy.
Xu S; a Department of Anesthesiology , Zhujiang Hospital of Southern Medical University , Guangzhou, Guangdong Province , China .
Pokaż więcej
Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2016 Jul; Vol. 32 (7), pp. 581-6. Date of Electronic Publication: 2016 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement/*physiology
Cell Proliferation/*physiology
Estradiol/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
NF-kappa B/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Review of Toxic Epidermal Necrolysis.
Autorzy:
Harris V; Sydney Medical School-Northern, University of Sydney, 2065 Sydney, Australia. .
Jackson C; Sutton Arthritis Research Laboratory, Kolling Institute, University of Sydney, 2065 Sydney, Australia. .
Cooper A; Dermatology Department, Royal North Shore Hospital, 2065 Sydney, Australia. .
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2016 Dec 18; Vol. 17 (12). Date of Electronic Publication: 2016 Dec 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antigens, Differentiation, T-Lymphocyte/*metabolism
Apoptosis/*physiology
Drug-Related Side Effects and Adverse Reactions/*pathology
Keratinocytes/*pathology
Mucous Membrane/*pathology
Stevens-Johnson Syndrome/*drug therapy
Stevens-Johnson Syndrome/*pathology
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Cyclosporine/therapeutic use ; Drug-Related Side Effects and Adverse Reactions/immunology ; Epidermis/pathology ; Fas Ligand Protein/metabolism ; Granulocyte Colony-Stimulating Factor/therapeutic use ; Granzymes/metabolism ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Infliximab/therapeutic use ; Perforin/metabolism ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Irradiation enhances susceptibility of tumor cells to the antitumor effects of TNF-α activated adipose derived mesenchymal stem cells in breast cancer model.
Autorzy:
Mohammadpour H; Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.; Adult Stem Cell Research Center, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Pourfathollah AA; Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Nikougoftar Zarif M; Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
Shahbazfar AA; Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2016 Jun 22; Vol. 6, pp. 28433. Date of Electronic Publication: 2016 Jun 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*therapy
Mesenchymal Stem Cell Transplantation/*methods
Mesenchymal Stem Cells/*drug effects
Radiotherapy/*methods
Tumor Necrosis Factor-alpha/*pharmacology
Adaptor Proteins, Signal Transducing ; Animals ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Survival ; Cells, Cultured ; Combined Modality Therapy ; Female ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; Mice ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Up-Regulation ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
TNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.
Autorzy:
Liu F; College of Life Sciences, Zhejiang University, Hangzhou, People's Republic of China.
Hu X
Zimmerman M
Waller JL
Wu P
Hayes-Jordan A
Lev D
Liu K
Pokaż więcej
Źródło:
PloS one [PLoS One] 2011 Jan 17; Vol. 6 (1), pp. e16241. Date of Electronic Publication: 2011 Jan 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Colonic Neoplasms/*pathology
Interferon-gamma/*physiology
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Tumor Necrosis Factor-alpha/*physiology
bcl-X Protein/*antagonists & inhibitors
Animals ; Caspase 8/metabolism ; Colonic Neoplasms/drug therapy ; Disease Models, Animal ; Mice ; Neoplasm Metastasis/drug therapy ; TNF-Related Apoptosis-Inducing Ligand/therapeutic use ; bcl-X Protein/blood
Czasopismo naukowe
Tytuł:
Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease.
Autorzy:
Ślebioda TJ; Department of Histology, Medical University of Gdańsk, Dębinki 1, 80-211 Gdańsk, Poland.
Kmieć Z; Department of Histology, Medical University of Gdańsk, Dębinki 1, 80-211 Gdańsk, Poland.
Pokaż więcej
Źródło:
Mediators of inflammation [Mediators Inflamm] 2014; Vol. 2014, pp. 325129. Date of Electronic Publication: 2014 Jun 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Inflammatory Bowel Diseases/*metabolism
Inflammatory Bowel Diseases/*pathology
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cytokine TWEAK ; Fas Ligand Protein/metabolism ; Humans ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Tumor Necrosis Factor Ligand Superfamily Member 14/metabolism ; Tumor Necrosis Factor Ligand Superfamily Member 15/metabolism ; Tumor Necrosis Factors/metabolism
Czasopismo naukowe
Tytuł:
Patients with ankylosing spondylitis and low disease activity because of anti-TNF-alpha therapy have higher TRAIL levels than controls: a potential compensatory effect.
Autorzy:
Genre F; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
López-Mejías R; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
Rueda-Gotor J; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
Miranda-Filloy JA; Rheumatology Division, Hospital Lucus Augusti, 27003 Lugo, Spain.
Ubilla B; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
Carnero-López B; Oncology Division, Hospital Del Bierzo, Ponferrada, 24411 León, Spain.
Palmou-Fontana N; Rheumatology Division, Hospital General de Almansa, 02640 Albacete, Spain.
Gómez-Acebo I; Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, IDIVAL, and CIBER Epidemiología y Salud Pública (CIBERESP), 39011 Santander, Spain.
Blanco R; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
Pina T; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
Ochoa R; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
González-Juanatey C; Cardiology Division, Hospital Lucus Augusti, 27003 Lugo, Spain.
Llorca J; Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, IDIVAL, and CIBER Epidemiología y Salud Pública (CIBERESP), 39011 Santander, Spain.
González-Gay MA; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, 39011 Santander, Spain.
Pokaż więcej
Źródło:
Mediators of inflammation [Mediators Inflamm] 2014; Vol. 2014, pp. 798060. Date of Electronic Publication: 2014 May 21.
Typ publikacji:
Journal Article
MeSH Terms:
Spondylitis, Ankylosing/*blood
TNF-Related Apoptosis-Inducing Ligand/*blood
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Adult ; Antibodies, Monoclonal/therapeutic use ; Antirheumatic Agents/therapeutic use ; Female ; Humans ; Infliximab ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
The tumour necrosis factor/TNF receptor superfamily: therapeutic targets in autoimmune diseases.
Autorzy:
Vinay DS; Section of Clinical Immunology, Allergy, and Rheumatology, Department of Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA.
Kwon BS
Pokaż więcej
Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2011 May; Vol. 164 (2), pp. 145-57. Date of Electronic Publication: 2011 Mar 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autoimmune Diseases/*drug therapy
Receptors, Tumor Necrosis Factor/*antagonists & inhibitors
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/therapeutic use ; Antigens, CD/immunology ; Autoantigens/immunology ; Autoimmune Diseases/immunology ; Disease Models, Animal ; Drug Design ; Drug Evaluation, Preclinical ; Female ; Humans ; Male ; Mice ; Mice, Inbred DBA ; Mice, Inbred NOD ; Mice, Knockout ; Receptors, Tumor Necrosis Factor/immunology ; TNF-Related Apoptosis-Inducing Ligand/antagonists & inhibitors ; TNF-Related Apoptosis-Inducing Ligand/immunology ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł:
Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors.
Autorzy:
Wenger T; Research Group Molecular Urooncology, German Cancer Research Center, Heidelberg, Germany.
Mattern J
Penzel R
Gassler N
Haas TL
Sprick MR
Walczak H
Krammer PH
Debatin KM
Herr I
Pokaż więcej
Źródło:
Cell death and differentiation [Cell Death Differ] 2006 Oct; Vol. 13 (10), pp. 1740-51. Date of Electronic Publication: 2006 Feb 10.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins/*genetics
Lentivirus/*genetics
Membrane Glycoproteins/*genetics
Receptors, Tumor Necrosis Factor/*metabolism
Tumor Necrosis Factor-alpha/*genetics
Apoptosis ; Apoptosis Regulatory Proteins/antagonists & inhibitors ; Base Sequence ; Cell Line, Tumor ; Cisplatin/pharmacology ; Death Domain Receptor Signaling Adaptor Proteins ; Drug Resistance, Neoplasm ; Endoplasmic Reticulum/metabolism ; Gene Transfer Techniques ; Genetic Therapy/methods ; Genetic Vectors ; Golgi Apparatus/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Jurkat Cells ; Membrane Glycoproteins/antagonists & inhibitors ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Neoplasm/genetics ; RNA, Neoplasm/metabolism ; RNA, Small Interfering/genetics ; Receptors, TNF-Related Apoptosis-Inducing Ligand ; Receptors, Tumor Necrosis Factor/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Signal Transduction ; TNF-Related Apoptosis-Inducing Ligand ; Transduction, Genetic ; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/metabolism ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Czasopismo naukowe
Tytuł:
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.
Autorzy:
Mühlethaler-Mottet A; Paediatric Oncology Research, Paediatric Department, University Hospital CHUV, CH-1011 Lausanne, Switzerland. />Flahaut M
Bourloud KB
Auderset K
Meier R
Joseph JM
Gross N
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2006 Aug 24; Vol. 6, pp. 214. Date of Electronic Publication: 2006 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histone Deacetylase Inhibitors*
Apoptosis/*drug effects
Apoptosis Regulatory Proteins/*metabolism
Caspases/*metabolism
Enzyme Inhibitors/*therapeutic use
Membrane Glycoproteins/*pharmacology
Neuroblastoma/*drug therapy
Tumor Necrosis Factor-alpha/*pharmacology
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Apoptosis Regulatory Proteins/pharmacology ; Butyrates/pharmacology ; Cell Survival ; Enzyme Inhibitors/pharmacology ; Humans ; Hydroxamic Acids/pharmacology ; Inhibitor of Apoptosis Proteins ; Microtubule-Associated Proteins/metabolism ; Mitochondria/metabolism ; Neoplasm Proteins/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand ; Receptors, Tumor Necrosis Factor/physiology ; Signal Transduction/drug effects ; Survivin ; TNF-Related Apoptosis-Inducing Ligand ; Tumor Cells, Cultured ; Vorinostat
Czasopismo naukowe
Tytuł:
Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM.
Autorzy:
Yin W; Department of Cell Biology and Signal Transduction, Institut de Génétique et de Biologie Moléculaire et Cellulaire, IGBMC/CNRS/INSERM/ULP, Illkirch Cedex, C U de Strasbourg, France.
Rossin A
Clifford JL
Gronemeyer H
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2006 Jun 22; Vol. 25 (26), pp. 3735-44. Date of Electronic Publication: 2006 Jan 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins/*metabolism
Drug Resistance, Neoplasm/*genetics
Intracellular Signaling Peptides and Proteins/*metabolism
Membrane Glycoproteins/*metabolism
Tretinoin/*pharmacology
Tumor Necrosis Factor-alpha/*metabolism
rab GTP-Binding Proteins/*genetics
Amino Acid Sequence ; Apoptosis/genetics ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/pharmacology ; Base Sequence ; Cell Differentiation/drug effects ; Cell Differentiation/genetics ; Humans ; Intracellular Signaling Peptides and Proteins/drug effects ; Intracellular Signaling Peptides and Proteins/genetics ; Leukemia, Myeloid/metabolism ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/pharmacology ; Molecular Sequence Data ; Mutagenesis, Insertional ; RNA, Long Noncoding ; Receptors, Retinoic Acid/drug effects ; Receptors, Retinoic Acid/genetics ; Receptors, Retinoic Acid/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand ; Receptors, Tumor Necrosis Factor/drug effects ; Receptors, Tumor Necrosis Factor/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/pharmacology ; Retinoic Acid Receptor alpha ; Retinoid X Receptors/drug effects ; Retinoid X Receptors/metabolism ; Signal Transduction ; TNF-Related Apoptosis-Inducing Ligand ; Tretinoin/metabolism ; Tumor Cells, Cultured ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/pharmacology ; rab GTP-Binding Proteins/drug effects ; rab GTP-Binding Proteins/metabolism ; rab27 GTP-Binding Proteins
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies