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Tytuł:
The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle.
Autorzy:
Ryan PJ; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Uranga S; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Stanelle ST; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Lewis MH; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
O'Reilly CL; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Cardin JM; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Deaver JW; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Morton AB; Soft Tissue Regeneration and Applied Biomaterials Laboratory, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA.
Fluckey JD; Muscle Biology Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, Gilchrist Building, 2929 Research Parkway, College Station, TX, 77843-4243, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 06; Vol. 14 (1), pp. 8094. Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
TOR Serine-Threonine Kinases*
Autophagy*/physiology
Aminopyridines*
Mechanistic Target of Rapamycin Complex 1/metabolism ; Muscle, Skeletal/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
mTOR Signaling: Recent Progress.
Autorzy:
Gargalionis AN; Department of Biopathology, 'Eginition' Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Papavassiliou KA; 'Sotiria' Hospital, Medical School, First University Department of Respiratory Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Papavassiliou AG; Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Editorial
MeSH Terms:
Signal Transduction*
TOR Serine-Threonine Kinases*
Humans
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In vitro modulation of mTOR and mGlur5 influence α-synuclein accumulation.
Autorzy:
Xing V; Department of Neuroscience, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Biggar K; Institute of Biochemistry and Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Ferguson SSG; Department of Neuroscience, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa Brain and Mind Research Institute, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Hayley S; Department of Neuroscience, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada. .
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Źródło:
Molecular brain [Mol Brain] 2024 Feb 15; Vol. 17 (1), pp. 9. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
alpha-Synuclein*/metabolism
Parkinson Disease*/metabolism
TOR Serine-Threonine Kinases*
Receptor, Metabotropic Glutamate 5*/metabolism
Humans ; Sirolimus/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The HIF-1α and mTOR Pathways Amplify Heterotopic Ossification.
Autorzy:
Wang H; Department of Medicine, Geriatric Medicine & Gerontology, Mayo Clinic, Rochester, MN 55905, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Kaplan FS; Department of Orthopaedic Surgery, The Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Medicine, The Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA 19104, USA.; The Center for Research in FOP and Related Disorders, The Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Pignolo RJ; Department of Medicine, Geriatric Medicine & Gerontology, Mayo Clinic, Rochester, MN 55905, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.; Department of Medicine, Divisions of Endocrinology, Hospital Internal Medicine, Rochester, MN 55905, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Jan 24; Vol. 14 (2). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Myositis Ossificans*/genetics
Myositis Ossificans*/metabolism
Ossification, Heterotopic*/genetics
Ossification, Heterotopic*/metabolism
TOR Serine-Threonine Kinases*/genetics
TOR Serine-Threonine Kinases*/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Animals ; Mice ; Ligands ; Mutation ; Signal Transduction ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An AMPK agonist suppresses the progress of colorectal cancer by regulating the polarization of TAM to M1 through inhibition of HIF-1α and mTOR signal pathway.
Autorzy:
Cao Y; Department of Laboratory Medicine, Hangzhou Cancer Hospital, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Shangcheng, China.
Wo M; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Xu C; Department of Laboratory Medicine, Affiliated Third Hospital of Zhejiang Traditional Chinese Medicine University, Xihu, Hangzhou, Zhejiang, China.
Fei X; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Jin J; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Shan Z; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Dec 01; Vol. 19 (6), pp. 1560-1567. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
Signal Transduction*/drug effects
TOR Serine-Threonine Kinases*/antagonists & inhibitors
TOR Serine-Threonine Kinases*/metabolism
Colorectal Neoplasms*/drug therapy
Tumor-Associated Macrophages*/drug effects
Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; HCT116 Cells ; Cell Polarity/drug effects ; THP-1 Cells ; AMP-Activated Protein Kinases/antagonists & inhibitors ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Gene Knockdown Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Valsartan Attenuated Homocysteine-Induced Impaired Autophagy and ER Stress in Human Umbilical Vein Endothelial Cells.
Autorzy:
Wu X; Department of Cardiology, The 5th Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Wang A; Department of Cardiology, The 5th Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Xu L; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Li M; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Zhai Q; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Wang W; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Li C; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Jin L; Department of Cardiology, The 5th Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
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Źródło:
Cardiovascular therapeutics [Cardiovasc Ther] 2023 Dec 13; Vol. 2023, pp. 8817431. Date of Electronic Publication: 2023 Dec 13 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Angiotensin, Type 1*/metabolism
TOR Serine-Threonine Kinases*/metabolism
Humans ; Human Umbilical Vein Endothelial Cells/metabolism ; Valsartan/pharmacology ; Glycogen Synthase Kinase 3 beta/metabolism ; Apoptosis ; Autophagy ; Homocysteine/toxicity ; Homocysteine/metabolism ; Endoplasmic Reticulum Stress
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
mTOR signalling pathway in stem cell bioactivities and angiogenesis potential.
Autorzy:
Lotfimehr H; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Mardi N; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Narimani S; Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Nasrabadi HT; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Karimipour M; Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Sokullu E; Koç University Research Center for Translational Medicine (KUTTAM), Istanbul, Turkey.
Rahbarghazi R; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
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Źródło:
Cell proliferation [Cell Prolif] 2023 Dec; Vol. 56 (12), pp. e13499. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Signal Transduction*
TOR Serine-Threonine Kinases*/metabolism
Animals ; Sirolimus/pharmacology ; Cell Proliferation ; Mammals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Periosteum-derived mesenchymal stem cell alleviates renal fibrosis through mTOR-mediated Treg differentiation.
Autorzy:
Luo Y; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Zhang K; Department of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wu J; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Zeng H; Shanghai Medical College, Fudan University, Shanghai, China.
Chen J; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Zhang P; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Guo J; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Xu C; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Niu X; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Cheuk YC; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Xu S; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Cao Y; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Zhao Y; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Zhu D; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Wang X; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Rong R; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
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Źródło:
Renal failure [Ren Fail] 2023 Dec; Vol. 45 (1), pp. 2212079.
Typ publikacji:
Journal Article
MeSH Terms:
Mesenchymal Stem Cells*/metabolism
Periosteum*
TOR Serine-Threonine Kinases*/metabolism
Animals ; Mice ; Cell Differentiation/genetics ; Fibrosis ; T-Lymphocytes, Regulatory
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Using Drosophila melanogaster to Dissect the Roles of the mTOR Signaling Pathway in Cell Growth.
Autorzy:
Frappaolo A; Istituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, 00185 Roma, Italy.
Giansanti MG; Istituto di Biologia e Patologia Molecolari del CNR, c/o Dipartimento di Biologia e Biotecnologie, Sapienza Università di Roma, 00185 Roma, Italy.
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Źródło:
Cells [Cells] 2023 Nov 14; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 14.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Drosophila melanogaster*/metabolism
TOR Serine-Threonine Kinases*/metabolism
Animals ; Signal Transduction/physiology ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Sirolimus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns.
Autorzy:
Barroso E; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Díaz M; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.; Endocrinology, Pediatric Research Institute, Sant Joan de Déu Children's Hospital, Barcelona, Esplugues, Spain.
Reguera AC; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Peyman M; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Balsinde J; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Biología y Genética Molecular, Consejo Superior de Investigaciones Científicas, Valladolid, Spain.
Jurado-Aguilar J; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Zhang M; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Rostami A; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Palomer X; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.
Ibáñez L; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain.; Endocrinology, Pediatric Research Institute, Sant Joan de Déu Children's Hospital, Barcelona, Esplugues, Spain.
Vázquez-Carrera M; Unitat de Farmacologia, Facultat de Farmàcia I Ciències de L'Alimentació, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain. .; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, Madrid, Spain. .; Pediatric Research Institute-Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Nov 13; Vol. 21 (1), pp. 326. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:
Placenta*/metabolism
TOR Serine-Threonine Kinases*/metabolism
Transcription Factor CHOP*/genetics
Amino Acid Transport System A*/genetics
Female ; Humans ; Infant, Newborn ; Pregnancy ; Birth Weight ; Fetal Growth Retardation/genetics ; Fetal Growth Retardation/metabolism ; Gestational Age ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Tunicamycin/pharmacology ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Signaling Pathways Leading to mTOR Activation Downstream Cytokine Receptors in Lymphocytes in Health and Disease.
Autorzy:
Fallone L; CIRI-Centre International de Recherche en Infectiologie (Team Lyacts), Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France.
Walzer T; CIRI-Centre International de Recherche en Infectiologie (Team Lyacts), Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France.
Marçais A; CIRI-Centre International de Recherche en Infectiologie (Team Lyacts), Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 13; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
TOR Serine-Threonine Kinases*
Signal Transduction*
Killer Cells, Natural ; CD8-Positive T-Lymphocytes ; Cell Cycle ; Cytokines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K-Akt-mTOR signalling.
Autorzy:
Liu J; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Zuo H; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Wang Z; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Wang W; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Qian X; State Key Laboratory of Reproductive Medicine, Gusu School, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, China.
Xie Y; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Peng D; State Key Laboratory of Oncology in South China, Cancer Center, Collaborative Innovation Center for Cancer Medicine, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Xie Y; State Key Laboratory of Oncology in South China, Cancer Center, Collaborative Innovation Center for Cancer Medicine, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Hong L; Department of Clinical Laboratory, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
You W; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Lou H; Department of Geriatrics, National Key Clinical Specialty, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Luo G; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Ren J; State Key Laboratory of Oncology in South China, Cancer Center, Collaborative Innovation Center for Cancer Medicine, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Shen B; State Key Laboratory of Reproductive Medicine, Gusu School, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, China.
Zheng J; Department of Public Health and Preventive Medicine, Changzhi Medical College, Changzhi, P. R. China.
Wang H; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.; Key Laboratory of Aging and Cancer Biology of Zhejiang Province, School of Basic Medical Sciences, Institute of Aging Research, Hangzhou Normal University, Hangzhou, China.
Ju Z; Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 Aug; Vol. 56 (8), pp. e13410. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
TOR Serine-Threonine Kinases*
Animals ; Mice ; RNA, Messenger/metabolism ; Cell Proliferation ; Muscles/metabolism ; Mammals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Glucose metabolism and function of CD4 Tregs are regulated by the TLR8/mTOR signal in an environment of SKOV3 cell growth.
Autorzy:
Wu M; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.; Department of Clinical Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Fu X; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Xu R; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.; Department of Anesthesiology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Liu S; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Li R; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.; Department of Gynecology, Women's Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital), Nanjing, China.
Xu J; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Shang W; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Chen X; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Wang T; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
Wang F; Department of Laboratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Branch of National Clinical Research Center for Laboratory Medicine, Nanjing, China.
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Źródło:
Cancer medicine [Cancer Med] 2023 Aug; Vol. 12 (15), pp. 16310-16322. Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toll-Like Receptor 8*/metabolism
TOR Serine-Threonine Kinases*/metabolism
Humans ; T-Lymphocytes, Regulatory ; Cell Proliferation ; Sirolimus/pharmacology ; Immunosuppressive Agents ; RNA, Messenger/metabolism ; Glucose/metabolism
Czasopismo naukowe
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Tytuł:
Regulation of mTOR Signaling: Emerging Role of Cyclic Nucleotide-Dependent Protein Kinases and Implications for Cardiometabolic Disease.
Autorzy:
Shi F; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Collins S; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 15; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cardiovascular Diseases*
Multiprotein Complexes*/metabolism
Sirolimus*
TOR Serine-Threonine Kinases*/metabolism
Animals ; Mice ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Nucleotides, Cyclic/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Rapamycin-Insensitive Companion of mTOR Protein/metabolism
Czasopismo naukowe
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Tytuł:
Isometric contraction induces transient increase of REDD1 expression in non-contracted muscles partly through glucocorticoids.
Autorzy:
Murakami T; Department of Nutrition, Shigakkan University, Obu, Japan.
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Źródło:
Physiological reports [Physiol Rep] 2023 Jun; Vol. 11 (11), pp. e15745.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glucocorticoids*/pharmacology
TOR Serine-Threonine Kinases*/metabolism
Mice ; Animals ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Isometric Contraction ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Muscle, Skeletal/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Phosphorylation/physiology ; Muscle Proteins/metabolism
Czasopismo naukowe
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Tytuł:
Transcriptomic Analysis of the Effect of Torin-2 on the Central Nervous System of Drosophila melanogaster .
Autorzy:
Vershinina YS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Krasnov GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Shaposhnikov MV; Institute of Biology, Komi Science Center, Ural Branch of RAS, 167000 Syktyvkar, Russia.
Fedorova MS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Pudova EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Katunina IV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Kornev AB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Zemskaya NV; Institute of Biology, Komi Science Center, Ural Branch of RAS, 167000 Syktyvkar, Russia.
Kudryavtsev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Bulavkina EV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Matveeva AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Ulyasheva NS; Institute of Biology, Komi Science Center, Ural Branch of RAS, 167000 Syktyvkar, Russia.
Guvatova ZG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Anurov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Moskalev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Kudryavtseva AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 22; Vol. 24 (10). Date of Electronic Publication: 2023 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
Drosophila melanogaster*/genetics
Drosophila melanogaster*/metabolism
TOR Serine-Threonine Kinases*/metabolism
Male ; Animals ; Female ; Transcriptome ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Sirolimus/pharmacology ; Central Nervous System/metabolism
Czasopismo naukowe
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Tytuł:
Glucose metabolic upregulation via phosphorylation of S6 ribosomal protein affects tumor progression in distal cholangiocarcinoma.
Autorzy:
Fujinaga A; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan. .
Hirashita T; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan.
Hirashita Y; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.; Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan.
Sakai K; Department of Division of Life Science Research, Faculty of Medicine, Oita University, Oita, Japan.
Kawamura M; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan.
Masuda T; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan.
Endo Y; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan.
Ohta M; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan.
Murakami K; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.
Inomata M; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Oita, 879-5593, Japan.
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2023 May 16; Vol. 23 (1), pp. 157. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
TOR Serine-Threonine Kinases*/metabolism
Cholangiocarcinoma*
Humans ; Phosphorylation ; Glucose Transporter Type 1/metabolism ; Ribosomal Proteins/metabolism ; Up-Regulation ; Glucose/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism
Czasopismo naukowe
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Tytuł:
Dietary restriction reveals sex-specific expression of the mTOR pathway genes in Japanese quails.
Autorzy:
Reda GK; Department of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Institute of Animal Science, Biotechnology and Nature Conservation, University of Debrecen, 4032, Debrecen, Hungary. .; Doctoral School of Animal Science, University of Debrecen, 4032, Debrecen, Hungary. .; Department of Evolutionary Zoology and Human Biology, University of Debrecen, 4032, Debrecen, Hungary. .
Ndunguru SF; Department of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Institute of Animal Science, Biotechnology and Nature Conservation, University of Debrecen, 4032, Debrecen, Hungary.; Doctoral School of Animal Science, University of Debrecen, 4032, Debrecen, Hungary.; Department of Evolutionary Zoology and Human Biology, University of Debrecen, 4032, Debrecen, Hungary.
Csernus B; Department of Evolutionary Zoology and Human Biology, University of Debrecen, 4032, Debrecen, Hungary.
Knop R; Department of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Institute of Animal Science, Biotechnology and Nature Conservation, University of Debrecen, 4032, Debrecen, Hungary.
Lugata JK; Doctoral School of Animal Science, University of Debrecen, 4032, Debrecen, Hungary.; Department of Animal Nutrition and Physiology, Faculty of Agriculture and Food Sciences and Environmental Management, University of Debrecen, 4032, Debrecen, Hungary.
Szabó C; Department of Animal Nutrition and Physiology, Faculty of Agriculture and Food Sciences and Environmental Management, University of Debrecen, 4032, Debrecen, Hungary.
Czeglédi L; Department of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Institute of Animal Science, Biotechnology and Nature Conservation, University of Debrecen, 4032, Debrecen, Hungary.
Lendvai ÁZ; Department of Evolutionary Zoology and Human Biology, University of Debrecen, 4032, Debrecen, Hungary.
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 09; Vol. 14 (1), pp. 8314. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Coturnix*/metabolism
Sirolimus*/metabolism
Animals ; Female ; Male ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
mTORC1 is required for differentiation of germline stem cells in the Drosophila melanogaster testis.
Autorzy:
Clémot M; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States of America.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, United States of America.
D'Alterio C; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Kwang AC; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Jones DL; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States of America.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, United States of America.; Departments of Anatomy, Division of Geriatrics, University of California, San Francisco, San Francisco, CA, United States of America.; Departments of Medicine, Division of Geriatrics, University of California, San Francisco, San Francisco, CA, United States of America.; Eli and Edythe Broad Center for Regeneration Medicine, University of California, San Francisco, San Francisco, CA, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 21; Vol. 19 (3), pp. e0300337. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Drosophila melanogaster*/metabolism
Drosophila Proteins*/metabolism
Animals ; Male ; Testis/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Cell Differentiation ; Drosophila/metabolism ; Stem Cells ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Germ Cells/metabolism
Czasopismo naukowe
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Tytuł:
Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications.
Autorzy:
Vrijmoeth HD; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.
Ursinus J; Department of Internal Medicine, Division of Infectious Diseases, Amsterdam UMC, Location AMC, University of Amsterdam, P.O. Box 22660, Amsterdam, 1100 DD, the Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands.
Botey-Bataller J; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Kuijpers Y; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Chu X; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
van de Schoor FR; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.
Scicluna BP; Department of Applied Biomedical Science, Faculty of Health Sciences, Mater Dei Hospital, University of Malta, MSD 2080, Msida, Malta.; Centre for Molecular Medicine and Biobanking, Biomedical Sciences, University of Malta, MSD 2080, Msida, Malta.
Xu CJ; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Netea MG; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, 53113, Bonn, Germany.
Kullberg BJ; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.
van den Wijngaard CC; National Institute for Public Health and Environment (RIVM), Center for Infectious Disease Control, Bilthoven, 3720 BA, the Netherlands.
Li Y; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, 30625, Hannover, Germany.
Hovius JW; Department of Internal Medicine, Division of Infectious Diseases, Amsterdam UMC, Location AMC, University of Amsterdam, P.O. Box 22660, Amsterdam, 1100 DD, the Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands.
Joosten LAB; Department of Internal Medicine and Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, 6500 HB, the Netherlands. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Mar 21; Vol. 24 (1), pp. 337. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Lyme Disease*/genetics
Lyme Disease*/diagnosis
Borrelia burgdorferi*/genetics
Borrelia*
Borrelia burgdorferi Group*/genetics
Humans ; Genome-Wide Association Study ; Prospective Studies ; Leukocytes, Mononuclear ; Disease Susceptibility ; Cytokines/genetics ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/therapeutic use ; Secretoglobins/genetics
Czasopismo naukowe
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Wyświetlanie 1-20 z 4994

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