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Tytuł:
Antimicrobial Resistance: Addressing a Global Threat to Humanity.
Autorzy:
Walsh TR; Ineos Oxford Institute for Antimicrobial Resistance, Department of Zoology, Oxford, United Kingdom.
Gales AC; Division of Infectious Diseases, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo, Brazil.
Laxminarayan R; Princeton University, Princeton, New Jersey, United States of America; One Health Trust, Bengaluru, India.
Dodd PC; Public Library of Science, San Francisco, United States of America and Cambridge, United Kingdom.
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Źródło:
PLoS medicine [PLoS Med] 2023 Jul 03; Vol. 20 (7), pp. e1004264. Date of Electronic Publication: 2023 Jul 03 (Print Publication: 2023).
Typ publikacji:
Editorial
MeSH Terms:
Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/therapeutic use
Drug Resistance, Bacterial*
Humans ; Global Health
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Global, regional, and national estimates of the impact of a maternal Klebsiella pneumoniae vaccine: A Bayesian modeling analysis.
Autorzy:
Kumar CK; Princeton University, Princeton, New Jersey, United States of America.
Sands K; Ineos Oxford Institute for Antimicrobial Resistance, Department of Zoology, Oxford, United Kingdom.
Walsh TR; Ineos Oxford Institute for Antimicrobial Resistance, Department of Zoology, Oxford, United Kingdom.
O'Brien S; Global Antibiotic Research and Development Partnership, Geneva, Switzerland.
Sharland M; Center for Neonatal and Paediatric Infection (CNPI), Institute of Infection and Immunity, St George's University of London, London, United Kingdom.
Lewnard JA; Division of Epidemiology, School of Public Health, University of California at Berkeley, Berkeley, California, United States of America.
Hu H; Bill & Melinda Gates Foundation, Seattle, Washington, United States of America.
Srikantiah P; Bill & Melinda Gates Foundation, Seattle, Washington, United States of America.
Laxminarayan R; Princeton University, Princeton, New Jersey, United States of America.; One Health Trust, Bengaluru, India.
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Źródło:
PLoS medicine [PLoS Med] 2023 May 22; Vol. 20 (5), pp. e1004239. Date of Electronic Publication: 2023 May 22 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Neonatal Sepsis*/epidemiology
Neonatal Sepsis*/prevention & control
Neonatal Sepsis*/microbiology
Perinatal Death*
Communicable Diseases*
Sepsis*
Vaccines*
Infant, Newborn ; Humans ; Female ; Pregnancy ; Klebsiella pneumoniae ; Meropenem ; Bayes Theorem ; South Africa
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria.
Autorzy:
Milton R; Centre for Trials Research, Cardiff University, Cardiff, UK. .
Modibbo F; Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.
Gillespie D; Centre for Trials Research, Cardiff University, Cardiff, UK.
Alkali FI; Department of Biochemistry, Bayero University, Kano, Nigeria.
Mukaddas AS; Department of Biological Sciences, Bayero University, Kano, Nigeria.
Kassim A; Department of Biological Sciences, Bayero University, Kano, Nigeria.
Sa'ad FH; Department of Medical Microbiology and Parasitology, Bayero University, Kano, Nigeria.
Tukur FM; Department of Biological Sciences, Bayero University, Kano, Nigeria.
Khalid RY; Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.
Muhammad MY; Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.
Bello M; Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.
Edwin CP; Department of Microbiology, Aminu Kano Teaching Hospital, Kano, Nigeria.
Ogudo E; Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.
Iregbu KC; Department of Medical Microbiology, National Hospital Abuja, Abuja, Nigeria.
Jones L; Department of Medical Microbiology Cardiff, Public Health Wales, University Hospital of Wales, Cardiff, UK.
Hood K; Centre for Trials Research, Cardiff University, Cardiff, UK.
Ghazal P; Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, UK.
Sanders J; School of Healthcare Sciences, Cardiff University, Cardiff, UK.
Hassan B; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Belga FJ; Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.
Walsh TR; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Department of Zoology, Ineos Institute of Antimicrobial Research, University of Oxford, Oxford, UK.
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Źródło:
BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2022 Sep 08; Vol. 22 (1), pp. 692. Date of Electronic Publication: 2022 Sep 08.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Maternal Health*
Stillbirth*/epidemiology
Female ; Humans ; Incidence ; Infant, Newborn ; Nigeria/epidemiology ; Pregnancy ; Tertiary Healthcare
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterisation of Staphylococci species from neonatal blood cultures in low- and middle-income countries.
Autorzy:
Sands K; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK. .; Department of Zoology, Ineos Oxford Institute of Antimicrobial Research, Oxford, UK. .
Carvalho MJ; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Institute of Biomedical Sciences, Department of Medical Sciences, University of Aveiro, Aveiro, Portugal.
Spiller OB; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Portal EAR; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Thomson K; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Department of Zoology, Ineos Oxford Institute of Antimicrobial Research, Oxford, UK.
Watkins WJ; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Mathias J; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Dyer C; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Centre for Trials Research, Cardiff University, Cardiff, UK.
Akpulu C; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Department of Zoology, Ineos Oxford Institute of Antimicrobial Research, Oxford, UK.; National Hospital Abuja, Abuja, Nigeria.
Andrews R; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Ferreira A; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Hender T; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Milton R; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Centre for Trials Research, Cardiff University, Cardiff, UK.
Nieto M; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Zahra R; Department of Microbiology, Quaid-I-Azam University, Islamabad, Pakistan.
Shirazi H; Pakistan Institute of Medical Sciences, Islamabad, Pakistan.
Muhammad A; Department of Microbiology, Quaid-I-Azam University, Islamabad, Pakistan.
Akif S; Department of Microbiology, Quaid-I-Azam University, Islamabad, Pakistan.
Jan MH; Department of Microbiology, Quaid-I-Azam University, Islamabad, Pakistan.
Iregbu K; National Hospital Abuja, Abuja, Nigeria.
Modibbo F; Murtala Muhammad Specialist Hospital, Kano, Nigeria.
Uwaezuoke S; Federal Medical Centre Jabi, Abuja, Nigeria.
Chan GJ; Division of Medical Critical Care, Boston Children's Hospital, Boston, MA, USA.; Department of Epidemiology, Harvard T.H Chan School of Public Health, Boston, MA, USA.
Bekele D; Department of Obstetrics and Gynecology, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Solomon S; Department of Microbiology, Immunology and Parasitology, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Basu S; Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases Beliaghata, Kolkata, India.
Nandy RK; Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases Beliaghata, Kolkata, India.
Naha S; Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases Beliaghata, Kolkata, India.
Mazarati JB; Rwanda Biomedical Centre, The National Reference Laboratory, Kigali, Rwanda.
Rucogoza A; Rwanda Biomedical Centre, The National Reference Laboratory, Kigali, Rwanda.
Gaju L; Rwanda Biomedical Centre, The National Reference Laboratory, Kigali, Rwanda.
Mehtar S; Unit of IPC, Stellenbosch University, Cape Town, South Africa.; Infection Control Africa Network, Cape Town, South Africa.
Bulabula ANH; Infection Control Africa Network, Cape Town, South Africa.; Department of Global Health, Stellenbosch University, Cape Town, South Africa.
Whitelaw A; Division of Medical Microbiology, Stellenbosch University, Cape Town, South Africa.; National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa.
Walsh TR; Department of Medical Microbiology, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.; Department of Zoology, Ineos Oxford Institute of Antimicrobial Research, Oxford, UK.
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Corporate Authors:
BARNARDS Group
Źródło:
BMC infectious diseases [BMC Infect Dis] 2022 Jul 01; Vol. 22 (1), pp. 593. Date of Electronic Publication: 2022 Jul 01.
Typ publikacji:
Journal Article
MeSH Terms:
Methicillin-Resistant Staphylococcus aureus*
Neonatal Sepsis*/epidemiology
Blood Culture ; Developing Countries ; Ethiopia ; Humans ; Infant, Newborn ; Prospective Studies ; Staphylococcus aureus/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prevalence and risk factors for antimicrobial resistance among newborns with gram-negative sepsis.
Autorzy:
Solomon S; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Akeju O; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Odumade OA; Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Ambachew R; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Gebreyohannes Z; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Van Wickle K; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Abayneh M; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Metaferia G; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Carvalho MJ; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom.; Department of Medical Sciences, Institute of Biomedicine, University of Aveiro, Aveiro, Portugal.
Thomson K; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom.
Sands K; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom.; Department of Zoology, University of Oxford, Oxford, United Kingdom.
Walsh TR; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom.; Department of Zoology, Ineos Oxford Institute of Antimicrobial Research, University of Oxford, Oxford, United Kingdom.
Milton R; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom.; Centre for Trials Research, Cardiff University, Cardiff, United Kingdom.
Goddard FGB; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Bekele D; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Chan GJ; St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.; Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Aug 03; Vol. 16 (8), pp. e0255410. Date of Electronic Publication: 2021 Aug 03 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Multiple, Bacterial*
Anti-Bacterial Agents/*pharmacology
Gram-Negative Bacteria/*growth & development
Gram-Negative Bacterial Infections/*epidemiology
Neonatal Sepsis/*microbiology
Ampicillin/pharmacology ; Cephalosporins/pharmacology ; Ethiopia/epidemiology ; Female ; Gentamicins/pharmacology ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacterial Infections/microbiology ; Humans ; Infant, Newborn ; Male ; Microbial Viability/drug effects ; Neonatal Sepsis/epidemiology ; Penicillin G/pharmacology ; Pregnancy ; Prevalence ; Tertiary Care Centers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular and epidemiological analysis of a Burkholderia cepacia sepsis outbreak from a tertiary care hospital in Bangladesh.
Autorzy:
Farzana R; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Jones LS; Public Health Wales Microbiology, University Hospital of Wales, Cardiff, United Kingdom.
Rahman MA; Department of Virology, Dhaka Medical College, Dhaka, Bangladesh.
Sands K; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Portal E; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Boostrom I; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Kalam MA; Department of Burn and Plastic Surgery, Sheikh Hasina National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh.
Hasan B; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Khan A; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Walsh TR; Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Apr 09; Vol. 14 (4), pp. e0008200. Date of Electronic Publication: 2020 Apr 09 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Outbreaks*
Burkholderia/*isolation & purification
Burkholderia Infections/*epidemiology
Cross Infection/*epidemiology
Adolescent ; Adult ; Bacteremia/epidemiology ; Bangladesh ; Burkholderia/genetics ; Burkholderia Infections/prevention & control ; Child ; Child, Preschool ; Cross Infection/prevention & control ; Cross Infection/transmission ; Electrophoresis, Gel, Pulsed-Field ; Female ; Genotype ; Humans ; Infant ; Infection Control/methods ; Intensive Care Units ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Patient Isolation ; Tertiary Care Centers ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inter-host Transmission of Carbapenemase-Producing Escherichia coli among Humans and Backyard Animals.
Autorzy:
Li J; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.; College of Veterinary Medicine, Hunan Agricultural University, Changsha, Hunan, China.
Bi Z; Shandong Academy of Clinical Medicine, Shandong Provincial Hospital, Jinan, Shandong, China.
Ma S; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Chen B; Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Center for Disease Control and Prevention, Jinan, Shandong, China.
Cai C; China Australia Joint Laboratory for Animal Health Big Data Analytics, College of Animal Science and Technology, Zhejiang Agricultural and Forestry University, Hangzhou, China.; Research and Innovation Office, Murdoch University, Murdoch, Australia.
He J; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Schwarz S; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Sun C; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhou Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yin J; School of Health Care Management, Shandong University, Jinan, China.; NHC Key Laboratory of Health Economics and Policy Research (Shandong University), Jinan, China.
Hulth A; Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.; Public Health Agency of Sweden, Stockholm, Sweden.
Wang Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Shen Z; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wang S; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wu C; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Nilsson LE; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Walsh TR; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Department of Medical Microbiology and Infectious Disease, Division of Infection and Immunity, Cardiff University, Cardiff, UK.
Börjesson S; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.; Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute (SVA), Uppsala, Sweden.
Shen J; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Sun Q; School of Health Care Management, Shandong University, Jinan, China.; NHC Key Laboratory of Health Economics and Policy Research (Shandong University), Jinan, China.
Wang Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.
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Źródło:
Environmental health perspectives [Environ Health Perspect] 2019 Oct; Vol. 127 (10), pp. 107009. Date of Electronic Publication: 2019 Oct 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins*
Carbapenem-Resistant Enterobacteriaceae*
Escherichia coli*
beta-Lactamases*
Drug Resistance, Multiple, Bacterial/*genetics
Animals ; Animals, Domestic ; Cattle ; China ; Dogs ; Humans ; Swine ; Zoonoses/transmission
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh.
Autorzy:
Farzana R; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
Jones LS; Public Health Wales Microbiology, University Hospital of Wales, Cardiff, United Kingdom. .
Rahman MA; Department of Virology, Dhaka Medical College, Dhaka, Bangladesh. .
Toleman MA; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
Sands K; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
Portal E; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
Boostrom I; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
Kalam MA; Sheikh Hasina National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh. .
Hassan B; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
Uddin AN; Dhaka Medical College Hospital, Dhaka, Bangladesh. .
Walsh TR; School of Medicine, Department of Medical Microbiology, Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom. .
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Źródło:
Journal of infection in developing countries [J Infect Dev Ctries] 2019 Aug 31; Vol. 13 (8), pp. 773-776. Date of Electronic Publication: 2019 Aug 31.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Bacterial*
Anti-Bacterial Agents/*pharmacology
Colistin/*pharmacology
Escherichia coli/*drug effects
Escherichia coli/*isolation & purification
Escherichia coli Infections/*microbiology
Escherichia coli Proteins/*genetics
Bangladesh ; Escherichia coli/genetics ; Hospitals ; Humans ; Microbial Sensitivity Tests ; Plasmids/analysis
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Crystal structures of VIM-1 complexes explain active site heterogeneity in VIM-class metallo-β-lactamases.
Autorzy:
Salimraj R; School of Cellular and Molecular Medicine, University of Bristol, UK.
Hinchliffe P; School of Cellular and Molecular Medicine, University of Bristol, UK.
Kosmopoulou M; School of Cellular and Molecular Medicine, University of Bristol, UK.
Tyrrell JM; Institute of Infection and Immunity, Cardiff University, UK.
Brem J; Department of Chemistry, University of Oxford, UK.
van Berkel SS; Department of Chemistry, University of Oxford, UK.
Verma A; Oxford Protein Production Facility UK, Rutherford Appleton Laboratory, Oxfordshire, UK.
Owens RJ; Oxford Protein Production Facility UK, Rutherford Appleton Laboratory, Oxfordshire, UK.
McDonough MA; Department of Chemistry, University of Oxford, UK.
Walsh TR; Institute of Infection and Immunity, Cardiff University, UK.
Schofield CJ; Department of Chemistry, University of Oxford, UK.
Spencer J; School of Cellular and Molecular Medicine, University of Bristol, UK.
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Źródło:
The FEBS journal [FEBS J] 2019 Jan; Vol. 286 (1), pp. 169-183. Date of Electronic Publication: 2018 Nov 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins/*chemistry
Bacterial Proteins/*metabolism
Enterobacteriaceae/*enzymology
Meropenem/*chemistry
Meropenem/*metabolism
Binding Sites ; Catalytic Domain ; Crystallography, X-Ray ; Protein Binding ; Protein Conformation ; Substrate Specificity ; beta-Lactamases/chemistry ; beta-Lactamases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
1.12 Å resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2.
Autorzy:
Coates K; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, England.
Walsh TR; Department of Medical Microbiology and Infectious Disease, Cardiff Institute of Infection and Immunity, UHW Main Building, Heath Park Hospital, Cardiff CF14 4XN, Wales.
Spencer J; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, England.
Hinchliffe P; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, England.
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Źródło:
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2017 Aug 01; Vol. 73 (Pt 8), pp. 443-449. Date of Electronic Publication: 2017 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Colistin/*chemistry
Escherichia coli/*chemistry
Escherichia coli Proteins/*chemistry
Plasmids/*chemistry
Amino Acid Sequence ; Catalytic Domain ; Cloning, Molecular ; Colistin/metabolism ; Crystallography, X-Ray ; Drug Resistance, Bacterial ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Models, Molecular ; Plasmids/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Protein Isoforms/chemistry ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Alignment ; Structural Homology, Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
mcr-1 in Enterobacteriaceae from Companion Animals, Beijing, China, 2012-2016.
Autorzy:
Lei L
Wang Y
Schwarz S
Walsh TR
Ou Y
Wu Y
Li M
Shen Z
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Źródło:
Emerging infectious diseases [Emerg Infect Dis] 2017 Apr; Vol. 23 (4), pp. 710-711.
Typ publikacji:
Journal Article
MeSH Terms:
Cats/*microbiology
Dogs/*microbiology
Enterobacteriaceae/*genetics
Escherichia coli Proteins/*genetics
Pets/*microbiology
Animals ; Anti-Bacterial Agents/pharmacology ; Beijing ; Colistin/pharmacology ; Drug Resistance, Bacterial
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.
Autorzy:
Hinchliffe P; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Yang QE; Institute of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Portal E; Institute of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Young T; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.
Li H; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Tooke CL; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Carvalho MJ; Institute of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Paterson NG; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.
Brem J; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK.
Niumsup PR; Department of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Tansawai U; Department of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Lei L; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Li M; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Shen Z; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wang Y; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Schofield CJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK.
Mulholland AJ; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.
Shen J; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Fey N; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.
Walsh TR; Institute of Infection and Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Spencer J; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
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Źródło:
Scientific reports [Sci Rep] 2017 Jan 06; Vol. 7, pp. 39392. Date of Electronic Publication: 2017 Jan 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Bacterial*
Anti-Bacterial Agents/*pharmacology
Colistin/*pharmacology
Escherichia coli/*enzymology
Escherichia coli Proteins/*chemistry
Escherichia coli Proteins/*metabolism
Catalytic Domain ; Crystallography, X-Ray ; DNA Mutational Analysis ; Disulfides/metabolism ; Escherichia coli/drug effects ; Escherichia coli Proteins/genetics ; Metalloproteins/chemistry ; Metalloproteins/genetics ; Metalloproteins/metabolism ; Microbial Sensitivity Tests ; Models, Molecular ; Protein Conformation ; Protein Disulfide-Isomerases/metabolism ; Zinc/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly.
Autorzy:
Bray DJ; Department of Chemistry University of Warwick, Coventry, United Kingdom; Centre for Scientific Computing, University of Warwick, Coventry, United Kingdom.
Walsh TR; Institute for Frontier Materials, Deakin University, Geelong, VIC, Australia.
Noro MG; Unilever R&D Port Sunlight, Wirral, United Kingdom.
Notman R; Department of Chemistry University of Warwick, Coventry, United Kingdom; Centre for Scientific Computing, University of Warwick, Coventry, United Kingdom.
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Źródło:
PloS one [PLoS One] 2015 Jul 16; Vol. 10 (7), pp. e0132706. Date of Electronic Publication: 2015 Jul 16 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Multimerization*
Disulfides/*chemistry
Intermediate Filaments/*chemistry
Keratin-1/*chemistry
Keratin-10/*chemistry
Amino Acid Sequence ; Humans ; Hydrogen Bonding ; Molecular Dynamics Simulation ; Molecular Sequence Data ; Protein Folding ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Sequence Alignment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.
Autorzy:
King AM; 1] M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario L8S 4K1, Canada [2] Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
Reid-Yu SA; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
Wang W; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
King DT; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.
De Pascale G; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
Strynadka NC; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.
Walsh TR; Cardiff Institute of Infection & Immunity, Cardiff University, Cardiff CF14 4XN, UK.
Coombes BK; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
Wright GD; 1] M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario L8S 4K1, Canada [2] Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada [3] Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4K1, Canada.
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Źródło:
Nature [Nature] 2014 Jun 26; Vol. 510 (7506), pp. 503-6.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
beta-Lactamase Inhibitors*
Aspartic Acid/*analogs & derivatives
Carbapenems/*pharmacology
Gram-Negative Bacteria/*drug effects
Thienamycins/*pharmacology
beta-Lactam Resistance/*drug effects
Animals ; Anti-Bacterial Agents/pharmacology ; Aspartic Acid/isolation & purification ; Aspartic Acid/pharmacology ; Aspergillus/chemistry ; Biological Products/isolation & purification ; Biological Products/pharmacology ; Drug Evaluation, Preclinical ; Drug Synergism ; Female ; Gram-Negative Bacteria/enzymology ; Gram-Negative Bacteria/genetics ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/enzymology ; Klebsiella pneumoniae/genetics ; Meropenem ; Mice ; beta-Lactamases/genetics ; beta-Lactamases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria.
Autorzy:
El Salabi A; Department of Infection, Immunity and Biochemistry, School of Medicine, Cardiff University, Heath Hospital, Heath Park, Cardiff CF14 4XN, UK.
Walsh TR
Chouchani C
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Źródło:
Critical reviews in microbiology [Crit Rev Microbiol] 2013 May; Vol. 39 (2), pp. 113-22. Date of Electronic Publication: 2012 Jun 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Drug Resistance, Multiple, Bacterial*
Interspersed Repetitive Sequences*
Bacterial Proteins/*metabolism
Gram-Negative Bacteria/*genetics
beta-Lactamases/*metabolism
Animals ; Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/enzymology ; Gram-Negative Bacterial Infections/drug therapy ; Gram-Negative Bacterial Infections/microbiology ; Humans ; beta-Lactamases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Occurrence of clinical isolates of Klebsiella pneumoniae harboring chromosomally mediated and plasmid-mediated CTX-M-15 β-lactamase in a Tunisian hospital.
Autorzy:
Chouchani C; a Université de Carthage, Institut Supérieur des Sciences et Technologies de l'Environnement de Borj-Cedria, Technopôle de Borj-Cedria, B.P. 1003, Hammam-Lif 2050, Tunisie.
El Salabi A
Marrakchi R
Abouelkacem N
Walsh TR
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Źródło:
Canadian journal of microbiology [Can J Microbiol] 2012 Sep; Vol. 58 (9), pp. 1099-103. Date of Electronic Publication: 2012 Aug 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hospitals*
Drug Resistance, Bacterial/*genetics
Klebsiella Infections/*microbiology
Klebsiella pneumoniae/*enzymology
Klebsiella pneumoniae/*genetics
beta-Lactamases/*genetics
Anti-Bacterial Agents/pharmacology ; DNA, Bacterial/genetics ; Humans ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/isolation & purification ; Plasmids/genetics ; Tunisia ; beta-Lactam Resistance/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular characterization of VIM-producing Klebsiella pneumoniae from Scandinavia reveals genetic relatedness with international clonal complexes encoding transferable multidrug resistance.
Autorzy:
Samuelsen Ø; Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway. />Toleman MA
Hasseltvedt V
Fuursted K
Leegaard TM
Walsh TR
Sundsfjord A
Giske CG
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Źródło:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2011 Dec; Vol. 17 (12), pp. 1811-6. Date of Electronic Publication: 2011 May 20.
Typ publikacji:
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Multilocus Sequence Typing*
Klebsiella Infections/*epidemiology
Klebsiella Infections/*microbiology
Klebsiella pneumoniae/*classification
Klebsiella pneumoniae/*genetics
beta-Lactamases/*metabolism
Aged, 80 and over ; Bacterial Proteins/genetics ; Cluster Analysis ; Drug Resistance, Multiple, Bacterial ; Female ; Genotype ; Humans ; Klebsiella pneumoniae/enzymology ; Klebsiella pneumoniae/isolation & purification ; Molecular Epidemiology ; Scandinavian and Nordic Countries/epidemiology ; beta-Lactamases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Association of bla(DHA-1) and qnrB genes carried by broad-host-range plasmids among isolates of Enterobacteriaceae at a Spanish hospital.
Autorzy:
Mata C; Departament de Genètica i de Microbiologia, Servei de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Institut d'Investigacions Biomèdiques Sant Pau, Barcelona, Spain.
Miró E
Toleman M
Rivera MA
Walsh TR
Navarro F
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Źródło:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2011 Oct; Vol. 17 (10), pp. 1514-7. Date of Electronic Publication: 2011 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Host Specificity*
Bacterial Proteins/*genetics
Enterobacteriaceae/*genetics
Enterobacteriaceae Infections/*microbiology
Plasmids/*genetics
beta-Lactamases/*genetics
Bacterial Typing Techniques ; Blotting, Southern ; DNA Transposable Elements ; Drug Resistance, Bacterial ; Enterobacteriaceae/classification ; Enterobacteriaceae/drug effects ; Enterobacteriaceae/isolation & purification ; Enterobacteriaceae Infections/epidemiology ; Genes, Bacterial/drug effects ; Hospitals ; Humans ; Microbial Sensitivity Tests/methods ; Polymerase Chain Reaction ; Spain/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
VIM and IMP metallo-β-lactamases and other extended-spectrum β-lactamases in Escherichia coli and Klebsiella pneumoniae from environmental samples in a Tunisian hospital.
Autorzy:
Chouchani C; Université de Carthage, Institut Supérieur des Sciences et Technologies de l'Environnement de Borj-Cedria, Technopôle de Borj-Cedria, Hammam-Lif, Tunisie. />Marrakchi R
Ferchichi L
El Salabi A
Walsh TR
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Źródło:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2011 Oct; Vol. 119 (10), pp. 725-32. Date of Electronic Publication: 2011 Jul 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli/*enzymology
Escherichia coli Infections/*microbiology
Klebsiella pneumoniae/*enzymology
beta-Lactamases/*biosynthesis
Colony Count, Microbial ; DNA, Bacterial/chemistry ; DNA, Bacterial/genetics ; Disease Outbreaks ; Drug Resistance, Multiple, Bacterial ; Electrophoresis, Gel, Pulsed-Field ; Escherichia coli/genetics ; Escherichia coli/isolation & purification ; Escherichia coli Infections/epidemiology ; Humans ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Retrospective Studies ; Tunisia/epidemiology ; beta-Lactamases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 29

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