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Tytuł :
Differential expression of members of SOX family of transcription factors in failing human hearts.
Autorzy :
Liu CF; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
Ni Y; Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.
Thachil V; Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio.
Morley M; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Moravec CS; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
Tang WHW; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: .
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Źródło :
Translational research : the journal of laboratory and clinical medicine [Transl Res] 2022 Apr; Vol. 242, pp. 66-78. Date of Electronic Publication: 2021 Oct 22.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiomyopathy, Dilated*/genetics
Transcription Factors*/genetics
Genome-Wide Association Study ; Humans ; RNA ; SOX Transcription Factors/genetics ; SOX Transcription Factors/metabolism ; SOXC Transcription Factors/genetics ; SOXE Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
A coherent FOXO3-SNAI2 feed-forward loop in autophagy.
Autorzy :
Guo X; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.; Hunan Normal University School of Medicine, 410081 Hunan, China.
Li Z; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.
Zhu X; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.
Zhan M; Zhuhai Precision Medical Center, Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, 510630 Guangdong, China.
Wu C; College of Traditional Chinese Medicine, North China University of Science and Technology, 063009 Hebei, China.
Ding X; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.
Peng K; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.
Li W; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.
Ma X; Westlake Laboratory of Life Sciences and Biomedicine, 310024 Hangzhou, China.
Lv Z; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.; National Clinical Research Center for Interventional Medicine, Shanghai 10th People's Hospital, 200072 Shanghai, China.
Lu L; Zhuhai Precision Medical Center, Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, 510630 Guangdong, China.
Xue L; Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 200092 Shanghai, China.; Zhuhai Precision Medical Center, Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, 510630 Guangdong, China.; National Clinical Research Center for Interventional Medicine, Shanghai 10th People's Hospital, 200072 Shanghai, China.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 15; Vol. 119 (11), pp. e2118285119. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy*/genetics
Cell Nucleus*/genetics
Cell Nucleus*/metabolism
Forkhead Box Protein O3*/genetics
Forkhead Box Protein O3*/metabolism
Snail Family Transcription Factors*/genetics
Snail Family Transcription Factors*/metabolism
Active Transport, Cell Nucleus ; Animals ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; HeLa Cells ; Humans
Czasopismo naukowe
Tytuł :
A feedforward circuit between KLF5 and lncRNA KPRT4 contributes to basal-like breast cancer.
Autorzy :
Du G; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; Kunming College of Life Sciences, University of Chinese Academy Sciences, Kunming, 650204, China.
Sun J; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; Kunming College of Life Sciences, University of Chinese Academy Sciences, Kunming, 650204, China.
Li Z; Department of Breast Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, China.
Zhang Q; Department of Breast Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, China.
Liu W; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; Kunming College of Life Sciences, University of Chinese Academy Sciences, Kunming, 650204, China.
Yang C; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China.
Zhao P; Department of Breast Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, China.
Wang X; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; Kunming College of Life Sciences, University of Chinese Academy Sciences, Kunming, 650204, China.
Yin Q; Medical Faculty of Kunming University of Science and Technology, Kunming, 650504, China.
Luo Y; Medical Faculty of Kunming University of Science and Technology, Kunming, 650504, China.
Song J; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; Kunming College of Life Sciences, University of Chinese Academy Sciences, Kunming, 650204, China.
Wen Y; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China.
Wang H; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; School of Life Science, University of Science & Technology of China, Hefei, 230027, China.
Chen CH; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China.
Hu G; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Science, Xiamen University, Xiamen, 361102, China.
Zhou Z; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China.
Mao X; Department of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Liu W; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Science, Xiamen University, Xiamen, 361102, China.
Liu Z; Department of Breast Disease, Henan Breast Cancer Center, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, 450008, China. Electronic address: .
Jiang D; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China; Kunming College of Life Sciences, University of Chinese Academy Sciences, Kunming, 650204, China. Electronic address: .
Chen C; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Kunming, 650201, China. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2022 May 28; Vol. 534, pp. 215618. Date of Electronic Publication: 2022 Mar 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*/pathology
Kruppel-Like Transcription Factors*/genetics
Kruppel-Like Transcription Factors*/metabolism
RNA, Long Noncoding*/genetics
Cell Line, Tumor ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis.
Autorzy :
Yuan Y; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Fan G; Precision Research Center for Refractory Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Liu Y; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Liu L; Department of Anesthesiology, Weifang Medical University, Weifang, 261000, China.
Zhang T; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Liu P; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Tu Q; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Zhang X; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China.
Luo S; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China.
Yao L; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. .
Chen F; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. .
Li J; Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China. .
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Źródło :
Cellular & molecular immunology [Cell Mol Immunol] 2022 Apr; Vol. 19 (4), pp. 504-515. Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Sepsis*
Transcription Factors*/metabolism
Animals ; Glycolysis ; Hexokinase ; Humans ; Immunity ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock.
Autorzy :
Zhang H; State Key Laboratory of Membrane Biology, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.; National Biomedical Imaging Center, College of Future Technology, Peking University, Beijing, China.
Shao S; Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. .
Zeng Y; Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Wang X; State Key Laboratory of Membrane Biology, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.; National Biomedical Imaging Center, College of Future Technology, Peking University, Beijing, China.
Qin Y; State Key Laboratory of Membrane Biology, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.; National Biomedical Imaging Center, College of Future Technology, Peking University, Beijing, China.
Ren Q; MOE Key Lab for Cellular Dynamics, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Xiang S; MOE Key Lab for Cellular Dynamics, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Wang Y; State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.; School of Life Sciences, Peking University, Beijing, China.
Xiao J; State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.; School of Life Sciences, Peking University, Beijing, China.
Sun Y; State Key Laboratory of Membrane Biology, Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China. .; National Biomedical Imaging Center, College of Future Technology, Peking University, Beijing, China. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2022 Mar; Vol. 24 (3), pp. 340-352. Date of Electronic Publication: 2022 Mar 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; Heat Shock Transcription Factors/genetics ; Heat-Shock Proteins/metabolism ; Heat-Shock Response/genetics
Czasopismo naukowe
Tytuł :
Molecular mechanisms of heat shock factor 1 regulation.
Autorzy :
Kmiecik SW; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH-Alliance, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany.
Mayer MP; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH-Alliance, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany. Electronic address: .
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Źródło :
Trends in biochemical sciences [Trends Biochem Sci] 2022 Mar; Vol. 47 (3), pp. 218-234. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Heat-Shock Response*
Transcription Factors*/metabolism
HSP70 Heat-Shock Proteins/metabolism ; Heat Shock Transcription Factors/genetics ; Heat Shock Transcription Factors/metabolism ; Molecular Chaperones/metabolism ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression.
Autorzy :
Protze J; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Naas S; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Krüger R; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Stöhr C; Institute of Pathology, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Kraus A; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Grampp S; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Wiesener M; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Schiffer M; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Hartmann A; Institute of Pathology, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Erlangen, Germany.
Wullich B; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Erlangen, Germany; Department of Urology and Pediatric Urology, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Schödel J; Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101699. Date of Electronic Publication: 2022 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/metabolism
Chromosomes, Human, Pair 14*
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Kidney Neoplasms*/genetics
Kidney Neoplasms*/metabolism
Transcription Factors*/biosynthesis
Transcription Factors*/genetics
Transcription Factors*/metabolism
Alleles ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Hypoxia/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Male ; Von Hippel-Lindau Tumor Suppressor Protein/genetics ; Von Hippel-Lindau Tumor Suppressor Protein/metabolism
Czasopismo naukowe
Tytuł :
USP20 regulates the stability of EMT transcription factor SOX4 and influences colorectal cancer metastasis.
Autorzy :
Guan Y; Department of General Surgery, Peking University First Hospital, Beijing 100034, China.
Jiang SR; Department of General Surgery, Peking University First Hospital, Beijing 100034, China.
Liu JG; Department of General Surgery, Peking University First Hospital, Beijing 100034, China.
Shi JR; Department of General Surgery, Peking University First Hospital, Beijing 100034, China.
Liu ZB; Department of General Surgery, Peking University First Hospital, Beijing 100034, China. Electronic address: .
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Źródło :
Pathology, research and practice [Pathol Res Pract] 2022 May; Vol. 233, pp. 153879. Date of Electronic Publication: 2022 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*/genetics
Transcription Factors*
Blotting, Western ; Cell Proliferation ; Gene Expression Regulation ; Humans ; SOXC Transcription Factors/genetics ; Ubiquitin Thiolesterase
Czasopismo naukowe
Tytuł :
Identification of Small-molecule YAP-TEAD inhibitors by High-throughput docking for the Treatment of colorectal cancer.
Autorzy :
Li L; Department of General Surgery, Taizhou People's Hospital, Taizhou 225300, PR China. Electronic address: .
Li R; Moray house school of education and sport, The university of Edinburgh, Edinburgh, UK.
Wang Y; Department of Emergency Internal Medicine, Taizhou People's Hospital, Taizhou 225300, PR China.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2022 May; Vol. 122, pp. 105707. Date of Electronic Publication: 2022 Feb 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms*/drug therapy
Transcription Factors*
Apoptosis ; DNA-Binding Proteins/metabolism ; Humans ; Muscle Proteins/metabolism ; TEA Domain Transcription Factors
Czasopismo naukowe
Tytuł :
E Protein Transcription Factors as Suppressors of T Lymphocyte Acute Lymphoblastic Leukemia.
Autorzy :
Parriott G; Committee on Immunology, University of Chicago, Chicago, IL, United States.
Kee BL; Committee on Immunology, University of Chicago, Chicago, IL, United States.; Committee on Cancer Biology, University of Chicago, Chicago, IL, United States.; Department of Pathology, University of Chicago, Chicago, IL, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2022 Apr 20; Vol. 13, pp. 885144. Date of Electronic Publication: 2022 Apr 20 (Print Publication: 2022).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Transcription Factors*/metabolism
Animals ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Mice ; Neoplasm Proteins/genetics ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Aryl hydrocarbon receptor and Krüppel like factor 10 mediate a transcriptional axis modulating immune homeostasis in mosquitoes.
Autorzy :
Kulkarni A; Biology Department, New Mexico State University, Las Cruces, NM, 88003, USA.
Pandey A; Biology Department, New Mexico State University, Las Cruces, NM, 88003, USA.
Trainor P; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM, 88003, USA.
Carlisle S; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM, 88003, USA.
Yu W; Biology Department, New Mexico State University, Las Cruces, NM, 88003, USA.
Kukutla P; Biology Department, New Mexico State University, Las Cruces, NM, 88003, USA.
Xu J; Biology Department, New Mexico State University, Las Cruces, NM, 88003, USA. .
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Źródło :
Scientific reports [Sci Rep] 2022 Apr 09; Vol. 12 (1), pp. 6005. Date of Electronic Publication: 2022 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Culicidae*/metabolism
Early Growth Response Transcription Factors*/genetics
Animals ; Homeostasis ; Kruppel-Like Transcription Factors/metabolism ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Aryl Hydrocarbon/metabolism
Czasopismo naukowe
Tytuł :
Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Autorzy :
Boisvert O; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada.
Létourneau D; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada.
Delattre P; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada.
Tremblay C; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada.
Jolibois É; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada.
Montagne M; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada.
Lavigne P; Département de biochimie et de génomique fonctionnelle, Institut de Pharmacologie de Sherbrooke and PROTÉO, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12 Avenue N, Sherbrooke, Quebec J1H 5N4, Canada. Electronic address: .
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Źródło :
Structure (London, England : 1993) [Structure] 2022 Apr 07; Vol. 30 (4), pp. 623-636.e5. Date of Electronic Publication: 2021 Dec 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription Factors*/metabolism
Zinc Fingers*
Amino Acid Sequence ; Binding Sites ; DNA/metabolism ; Gene Expression Regulation ; Kruppel-Like Transcription Factors
Czasopismo naukowe
Tytuł :
A Heme-Binding Transcription Factor BACH1 Regulates Lactate Catabolism Suggesting a Combined Therapy for Triple-Negative Breast Cancer.
Autorzy :
Padilla J; Department of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, Washington, DC 20037, USA.
Lee BS; Department of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, Washington, DC 20037, USA.
Zhai K; Department of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, Washington, DC 20037, USA.
Rentz B; Animal Research, Office of the Vice Provost for Research, 1922 F Street NW, Washington, DC 20052, USA.
Bobo T; Animal Research, Office of the Vice Provost for Research, 1922 F Street NW, Washington, DC 20052, USA.
Dowling NM; Department of Acute & Chronic Care, School of Nursing, Washington, DC 20037, USA.; Department of Epidemiology, Milken Institute School of Public Health, Washington, DC 20052, USA.; Center for Aging, Health and Humanities, Washington, DC 20006, USA.
Lee J; Department of Biochemistry and Molecular Medicine, School of Medicine and Health Sciences, Washington, DC 20037, USA.; GW Cancer Center, The George Washington University, Washington, DC 20037, USA.
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Źródło :
Cells [Cells] 2022 Mar 31; Vol. 11 (7). Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms :
Basic-Leucine Zipper Transcription Factors*/metabolism
Lactic Acid*/metabolism
Triple Negative Breast Neoplasms*/metabolism
Heme/metabolism ; Humans ; Monocarboxylic Acid Transporters/genetics ; Monocarboxylic Acid Transporters/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
CB2R Activation Regulates TFEB-Mediated Autophagy and Affects Lipid Metabolism and Inflammation of Astrocytes in POCD.
Autorzy :
Zhang L; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Wang X; Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yu W; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Ying J; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Fang P; Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zheng Q; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Feng X; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Hu J; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Xiao F; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Chen S; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Wei G; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Lin Y; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Liu X; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Yang D; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Fang Y; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Xu G; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
Hua F; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.; Key Laboratory of Anesthesiology of Jiangxi Province, Nanchang, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2022 Mar 22; Vol. 13, pp. 836494. Date of Electronic Publication: 2022 Mar 22 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes*/metabolism
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism
Postoperative Cognitive Complications*
Receptor, Cannabinoid, CB2*
Animals ; Autophagy/genetics ; Inflammation/metabolism ; Lipid Metabolism ; Mice ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Normal and Neoplastic Growth Suppression by the Extended Myc Network.
Autorzy :
Prochownik EV; Division of Hematology/Oncology, The Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, USA.; The Department of Microbiology and Molecular Genetics, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.; The Hillman Cancer Center of UPMC, Pittsburgh, PA 15224, USA.; The Pittsburgh Liver Research Center, Pittsburgh, PA 15224, USA.
Wang H; Division of Hematology/Oncology, The Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, USA.
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Źródło :
Cells [Cells] 2022 Feb 21; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/genetics
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism
Neoplasms*/genetics
Basic Helix-Loop-Helix Transcription Factors ; Humans ; Repressor Proteins/physiology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia.
Autorzy :
Wang H; Division of Hematology/Oncology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Lu J; Division of Hematology/Oncology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Alencastro F; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; McGowan Institute for Regenerative Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Roberts A; Division of Hematology/Oncology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Fiedor J; Division of Hematology/Oncology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Carroll P; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Eisenman RN; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Ranganathan S; Department of Pathology, Cincinnati Children's Hospital, Cincinnati, Ohio.
Torbenson M; Department of Laboratory Medicine and Pathology, The Mayo Clinic, Rochester, Minnesota.
Duncan AW; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; McGowan Institute for Regenerative Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
Prochownik EV; Division of Hematology/Oncology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania; Hillman Comprehensive Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Microbiology and Molecular Genetics, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address: .
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Źródło :
Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2022; Vol. 13 (6), pp. 1785-1804. Date of Electronic Publication: 2022 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/genetics
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism
Neoplasms*/genetics
Animals ; Basic Helix-Loop-Helix Transcription Factors ; Carcinogenesis/genetics ; Cell Transformation, Neoplastic ; Liver Regeneration ; Mice ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Exosome miR-23a-3p from Osteoblast Alleviates Spinal Cord Ischemia/Reperfusion Injury by Down-Regulating KLF3-Activated CCNL2 Transcription.
Autorzy :
Wu C; Department of Hand Surgery and Plastic Surgery, The First People's Hospital of Linping District, Hangzhou, China.
Zhu Q; Department of Pediatric Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Yao Y; Department of Hand Surgery and Plastic Surgery, The First People's Hospital of Linping District, Hangzhou, China.
Shi Z; Department of Hand Surgery and Plastic Surgery, The First People's Hospital of Linping District, Hangzhou, China.
Jin C; Department of Hand Surgery and Plastic Surgery, The First People's Hospital of Linping District, Hangzhou, China.
Chen L; Department of Hand Surgery and Plastic Surgery, The First People's Hospital of Linping District, Hangzhou, China.
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Źródło :
Developmental neuroscience [Dev Neurosci] 2022; Vol. 44 (3), pp. 121-130. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclins*/genetics
Cyclins*/metabolism
Exosomes*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Reperfusion Injury*/metabolism
Spinal Cord Ischemia*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Cell Line ; Humans ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Osteoblasts/metabolism
Czasopismo naukowe
Tytuł :
The inhibitory effect of LINC00261 upregulation on the pancreatic cancer EMT process is mediated by KLF13 via the mTOR signaling pathway.
Autorzy :
Li B; School of Life Science and Technology, China Pharmaceutical University, Jiangsu, 211198, P.R. China.
Pang S; School of Life Science and Technology, China Pharmaceutical University, Jiangsu, 211198, P.R. China.
Dou J; School of Life Science and Technology, China Pharmaceutical University, Jiangsu, 211198, P.R. China.
Zhou C; School of Life Science and Technology, China Pharmaceutical University, Jiangsu, 211198, P.R. China.
Shen B; Department of General Surgery, Pancreatic Disease Center, Research Institute of Pancreatic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, P.R. China. .; Institute of Translational Medicine, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiaotong University, Shanghai, 200025, P.R. China. .
Zhou Y; Department of General Surgery, Pancreatic Disease Center, Research Institute of Pancreatic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, P.R. China. .; Institute of Translational Medicine, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiaotong University, Shanghai, 200025, P.R. China. .
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Źródło :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2022 Jun; Vol. 24 (6), pp. 1059-1072. Date of Electronic Publication: 2022 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Kruppel-Like Transcription Factors*/genetics
MicroRNAs*/genetics
MicroRNAs*/metabolism
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Cell Cycle Proteins ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Epithelial-Mesenchymal Transition ; Humans ; In Situ Hybridization, Fluorescence ; Repressor Proteins ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Up-Regulation
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
The chromatin remodelling ATPase BRAHMA interacts with GATA-family transcription factor GNC to regulate flowering time in Arabidopsis.
Autorzy :
Yang J; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
Xu Y; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China.
Wang J; Innovative Center of Molecular Genetics and Evolution, School of Life Sciences, Guangzhou University, Guangzhou, China.
Gao S; College of Light Industry and Food Science, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.; Academy of Contemporary Agricultural Engineering Innovations, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Huang Y; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
Hung FY; Institute of Plant Biology, National Taiwan University, Taipei 106, Taiwan.
Li T; Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Li Q; Guangdong Provincial Key Laboratory for Crop Germplasm Resources Preservation and Utilization, Agrobiological Gene Research Center, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Yue L; Innovative Center of Molecular Genetics and Evolution, School of Life Sciences, Guangzhou University, Guangzhou, China.
Wu K; Institute of Plant Biology, National Taiwan University, Taipei 106, Taiwan.
Yang S; Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.; Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
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Źródło :
Journal of experimental botany [J Exp Bot] 2022 Jan 27; Vol. 73 (3), pp. 835-847.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Triphosphatases*/genetics
Adenosine Triphosphatases*/metabolism
Arabidopsis*/growth & development
Arabidopsis*/metabolism
Arabidopsis Proteins*/genetics
Arabidopsis Proteins*/metabolism
Chromatin Assembly and Disassembly*
Transcription Factors*/genetics
Transcription Factors*/metabolism
GATA Transcription Factors/genetics ; GATA Transcription Factors/metabolism ; Gene Expression Regulation, Plant
Czasopismo naukowe
Tytuł :
The antibiotic drug trimethoprim suppresses tumour growth and metastasis via targeting Snail.
Autorzy :
Ren BX; State Key Laboratory of Natural Medicines, School of Biopharmacy, China Pharmaceutical University, Nanjing, China.
Li Y; State Key Laboratory of Natural Medicines, School of Biopharmacy, China Pharmaceutical University, Nanjing, China.
Li HM; State Key Laboratory of Natural Medicines, Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, China.
Lu T; State Key Laboratory of Natural Medicines, Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, China.
Wu ZQ; State Key Laboratory of Natural Medicines, School of Biopharmacy, China Pharmaceutical University, Nanjing, China.
Fu R; State Key Laboratory of Natural Medicines, School of Biopharmacy, China Pharmaceutical University, Nanjing, China.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2022 Jun; Vol. 179 (11), pp. 2659-2677. Date of Electronic Publication: 2022 Mar 15.
Typ publikacji :
Journal Article
MeSH Terms :
Transcription Factors*/metabolism
Trimethoprim*/pharmacology
Animals ; Anti-Bacterial Agents/pharmacology ; Cell Line, Tumor ; Cell Movement ; Molecular Docking Simulation ; Neoplasm Metastasis ; Snail Family Transcription Factors/metabolism
Czasopismo naukowe

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