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Tytuł :
t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming.
Autorzy :
Kellaway S; Institute of Cancer and Genomica Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham B152TT, UK.
Chin PS; Institute of Cancer and Genomica Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham B152TT, UK.
Barneh F; Princess Máxima Centrum for Pediatric Oncology, Heidelberglaan 25, 3584CS Utrecht, The Netherlands.
Bonifer C; Institute of Cancer and Genomica Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham B152TT, UK.
Heidenreich O; Princess Máxima Centrum for Pediatric Oncology, Heidelberglaan 25, 3584CS Utrecht, The Netherlands.
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Źródło :
Cells [Cells] 2020 Dec 13; Vol. 9 (12). Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Translocation, Genetic*
Chromatin/*metabolism
Leukemia, Myeloid, Acute/*pathology
Animals ; Chromatin/chemistry ; Core Binding Factor Alpha 2 Subunit/genetics ; Core Binding Factor Alpha 2 Subunit/metabolism ; Epigenomics ; Gene Expression Regulation ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/therapy ; Mutation ; RUNX1 Translocation Partner 1 Protein/genetics ; RUNX1 Translocation Partner 1 Protein/metabolism
Czasopismo naukowe
Tytuł :
RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.
Autorzy :
Chin PS; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Assi SA; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Ptasinska A; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Imperato MR; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Cockerill PN; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Bonifer C; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. Electronic address: .
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Źródło :
Experimental hematology [Exp Hematol] 2020 Dec; Vol. 92, pp. 62-74. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosomes, Human, Pair 21*/genetics
Chromosomes, Human, Pair 21*/metabolism
Chromosomes, Human, Pair 8*/genetics
Chromosomes, Human, Pair 8*/metabolism
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Mutation, Missense*
Transcription, Genetic*
Translocation, Genetic*
Chromatin/*metabolism
Core Binding Factor Alpha 2 Subunit/*metabolism
Proto-Oncogene Proteins c-kit/*metabolism
RUNX1 Translocation Partner 1 Protein/*metabolism
Amino Acid Substitution ; Chromatin/pathology ; Core Binding Factor Alpha 2 Subunit/genetics ; Female ; Gene Expression Regulation, Leukemic ; HEK293 Cells ; Humans ; Male ; Proto-Oncogene Proteins c-kit/genetics ; RUNX1 Translocation Partner 1 Protein/genetics
Czasopismo naukowe
Tytuł :
Epigenetic silencing of miR564 contributes to the leukemogenesis of t(8;21) acute myeloid leukemia.
Autorzy :
Yang E; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Guan W; Department of Hematology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Gong D; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Gao X; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Han C; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Zhang J; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Wang H; School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, P.R. China.
Wang M; Department of Hematology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Li Y; Central Laboratory, Shenzhen University General Hospital, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Yu L; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
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Źródło :
Clinical science (London, England : 1979) [Clin Sci (Lond)] 2020 Dec 11; Vol. 134 (23), pp. 3079-3091.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epigenesis, Genetic*
Gene Silencing*
Translocation, Genetic*
Carcinogenesis/*genetics
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*pathology
MicroRNAs/*metabolism
Animals ; Apoptosis/genetics ; Base Sequence ; Carcinogenesis/pathology ; Cell Cycle Checkpoints/genetics ; Cell Differentiation/genetics ; Cell Line, Tumor ; Core Binding Factor Alpha 2 Subunit/metabolism ; Cyclin D1/metabolism ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; DNA Methylation/genetics ; Female ; Gene Expression Regulation, Leukemic ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; Oncogene Proteins, Fusion/metabolism ; Promoter Regions, Genetic/genetics ; Protein Binding/genetics ; RUNX1 Translocation Partner 1 Protein/metabolism ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Morphological characteristics, cytogenetic profile, and outcome of RUNX1-RUNX1T1-positive acute myeloid leukemia: Experience of an Indian tertiary care center.
Autorzy :
Gupta R; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Yadav S; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Parashar Y; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Rahman K; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Singh MK; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Chandra D; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Gupta A; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
Nityanand S; Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Uttar Pradesh, Lucknow, India.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2020 Feb; Vol. 42 (1), pp. 37-45. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Journal Article
MeSH Terms :
Chromosomes, Human, Pair 21*/genetics
Chromosomes, Human, Pair 21*/metabolism
Chromosomes, Human, Pair 8*/genetics
Chromosomes, Human, Pair 8*/metabolism
Core Binding Factor Alpha 2 Subunit*/blood
Core Binding Factor Alpha 2 Subunit*/genetics
Leukemia, Myeloid, Acute*/blood
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/mortality
Sarcoma, Myeloid*/blood
Sarcoma, Myeloid*/drug therapy
Sarcoma, Myeloid*/genetics
Sarcoma, Myeloid*/mortality
Translocation, Genetic*
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Adolescent ; Adult ; Aged ; Asparaginase/administration & dosage ; Child ; Child, Preschool ; Daunorubicin/administration & dosage ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Prednisone/administration & dosage ; RUNX1 Translocation Partner 1 Protein/blood ; RUNX1 Translocation Partner 1 Protein/genetics ; Retrospective Studies ; Survival Rate ; Vincristine/administration & dosage
SCR Protocol :
PVDA protocol
Czasopismo naukowe
Tytuł :
Translocation of vaginal microbiota is involved in impairment and protection of uterine health.
Autorzy :
Wang J; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Li Z; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Ma X; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Du L; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Jia Z; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.; Department of Gynecology, Aviation General Hospital of China Medical University, Beijing, China.
Cui X; Department of Gynecology, Aviation General Hospital of China Medical University, Beijing, China.
Yu L; Department of Gynecology, Aviation General Hospital of China Medical University, Beijing, China.
Yang J; Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Xiao L; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Zhang B; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Fan H; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Zhao F; Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China. .; University of Chinese Academy of Sciences, Beijing, China. .; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China. .; Key Laboratory of Systems Biology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 07; Vol. 12 (1), pp. 4191. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Translocation*
Microbiota*
Reproductive Health*
Endometritis/*microbiology
Vagina/*microbiology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Chronic Disease ; Cohort Studies ; DNA, Bacterial/isolation & purification ; Disease Models, Animal ; Endometritis/epidemiology ; Endometritis/pathology ; Endometrium/microbiology ; Endometrium/pathology ; Female ; Humans ; Middle Aged ; Protective Factors ; RNA, Ribosomal, 16S/genetics ; Rats ; Risk Factors ; Women's Health ; Young Adult
Czasopismo naukowe
Tytuł :
2021 Update on Diagnostic Markers and Translocation in Salivary Gland Tumors.
Autorzy :
Meyer MT; Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, Germany.
Watermann C; Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, Germany.
Dreyer T; Institute for Pathology, Justus Liebig University, Langhansstrasse 10, 35392 Gießen, Germany.
Ergün S; Institute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, Germany.
Karnati S; Institute for Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, Koellikerstrasse 6, 97070 Würzburg, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 24; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biomarkers, Tumor*
Genetic Predisposition to Disease*
Genetic Testing*/methods
Genetic Testing*/standards
Translocation, Genetic*
Salivary Gland Neoplasms/*diagnosis
Salivary Gland Neoplasms/*genetics
Genetic Association Studies ; Humans ; Neoplasm Grading ; Neoplasm Staging ; Preoperative Care/methods ; Preoperative Care/standards ; Salivary Gland Neoplasms/metabolism ; Salivary Gland Neoplasms/therapy
Czasopismo naukowe
Tytuł :
The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins.
Autorzy :
Geller AM; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel.
Pollin I; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel.
Zlotkin D; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel.
Danov A; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel.
Nachmias N; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel.
Andreopoulos WB; Department of Computer Science, San Jose State University, San Jose, CA, USA.
Shemesh K; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel.
Levy A; Department of Plant Pathology and Microbiology, the Robert H. Smith Faculty of Food and Environment, the Hebrew University of Jerusalem, Rehovot, Israel. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 18; Vol. 12 (1), pp. 3743. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Archaea/*genetics
Bacteria/*genetics
Contractile Proteins/*genetics
Protein Translocation Systems/*genetics
Toxins, Biological/*metabolism
Animals ; Archaea/metabolism ; Bacteria/metabolism ; Bacteriophages/metabolism ; Fungi ; Nematoda ; Protein Translocation Systems/metabolism ; Protein Transport/physiology ; Toxins, Biological/genetics
Czasopismo naukowe
Tytuł :
3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia.
Autorzy :
Yang L; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Beijing, China.
Chen F; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Bioinformatics Division, BNRist, Department of Automation, Tsinghua University, Beijing, China.; Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing, China.; Tsinghua-Peking Center for Life Sciences, Beijing, China.
Zhu H; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Beijing, China.; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Hubei, China.
Chen Y; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Bioinformatics Division, BNRist, Department of Automation, Tsinghua University, Beijing, China.; Department of Biochemistry and Molecular Biology, The State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Dong B; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Beijing, China.
Shi M; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Bioinformatics Division, BNRist, Department of Automation, Tsinghua University, Beijing, China.; School of Medicine, Tsinghua University, Beijing, China.
Wang W; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Beijing, China.
Jiang Q; Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China.
Zhang L; Department of Pediatrics, Peking University People's Hospital, Beijing, China.
Huang X; Peking-Tsinghua Center for Life Sciences, Beijing, China. .; Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China. .
Zhang MQ; MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Bioinformatics Division, BNRist, Department of Automation, Tsinghua University, Beijing, China. .; School of Medicine, Tsinghua University, Beijing, China. .; Department of Biological Sciences, Center for Systems Biology, The University of Texas, Richardson, TX, USA. .
Wu H; The MOE Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing, China. .; Peking-Tsinghua Center for Life Sciences, Beijing, China. .; Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 17; Vol. 12 (1), pp. 3708. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Conformation*
Translocation, Genetic*
Chromosomes/*metabolism
Homeodomain Proteins/*genetics
Leukemia-Lymphoma, Adult T-Cell/*genetics
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
T-Lymphocytes/*metabolism
Acetylation ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Line, Tumor ; Cell Lineage ; Child ; Chromatin Immunoprecipitation Sequencing ; Chromosomes/genetics ; Disease Progression ; Enhancer Elements, Genetic ; Gene Expression Profiling ; Gene Expression Regulation, Leukemic/genetics ; Gene Expression Regulation, Leukemic/immunology ; Gene Ontology ; Hematopoiesis/genetics ; Histones/metabolism ; Homeodomain Proteins/metabolism ; Humans ; Immunophenotyping ; Leukemia-Lymphoma, Adult T-Cell/metabolism ; Leukemia-Lymphoma, Adult T-Cell/mortality ; Leukemia-Lymphoma, Adult T-Cell/pathology ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Nuclear Pore Complex Proteins/genetics ; Nuclear Pore Complex Proteins/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/mortality ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Prognosis ; T-Lymphocytes/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing.
Autorzy :
Allahyar A; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Pieterse M; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Swennenhuis J; Cergentis BV, Utrecht, the Netherlands.
Los-de Vries GT; Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, the Netherlands.
Yilmaz M; Cergentis BV, Utrecht, the Netherlands.
Leguit R; University Medical Centre Utrecht, Department of Pathology, Utrecht, the Netherlands.
Meijers RWJ; University Medical Centre Utrecht, Department of Pathology, Utrecht, the Netherlands.
van der Geize R; Laboratorium Pathologie Oost-Nederland, Hengelo, the Netherlands.
Vermaat J; Leiden University Medical Centre, Department of Hematology, Leiden, the Netherlands.
Cleven A; Leiden University Medical Center, Department of Pathology, Leiden, the Netherlands.
van Wezel T; Leiden University Medical Center, Department of Pathology, Leiden, the Netherlands.
Diepstra A; University of Groningen, University Medical Centre Groningen, Department of Pathology & Medical Biology, Groningen, the Netherlands.
van Kempen LC; University of Groningen, University Medical Centre Groningen, Department of Pathology & Medical Biology, Groningen, the Netherlands.
Hijmering NJ; Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, the Netherlands.
Stathi P; Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, the Netherlands.
Sharma M; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Melquiond ASJ; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
de Vree PJP; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Verstegen MJAM; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Krijger PHL; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.
Hajo K; Cergentis BV, Utrecht, the Netherlands.
Simonis M; Cergentis BV, Utrecht, the Netherlands.
Rakszewska A; Cergentis BV, Utrecht, the Netherlands.
van Min M; Cergentis BV, Utrecht, the Netherlands.
de Jong D; Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, the Netherlands.
Ylstra B; Amsterdam UMC-Vrije Universiteit Amsterdam, Department of Pathology and Cancer Center Amsterdam, Amsterdam, the Netherlands.
Feitsma H; Cergentis BV, Utrecht, the Netherlands.
Splinter E; Cergentis BV, Utrecht, the Netherlands. .
de Laat W; Oncode Institute & Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 07; Vol. 12 (1), pp. 3361. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Translocation, Genetic*
High-Throughput Nucleotide Sequencing/*methods
Lymphoma, B-Cell/*genetics
Lymphoma, Non-Hodgkin/*genetics
Paraffin Embedding/*methods
Tissue Fixation/*methods
Computational Biology/methods ; Gene Rearrangement ; Genes, bcl-2/genetics ; Genes, myc/genetics ; Humans ; In Situ Hybridization, Fluorescence/methods ; Lymphoma, B-Cell/diagnosis ; Lymphoma, Non-Hodgkin/diagnosis ; Proto-Oncogene Proteins c-bcl-6/genetics ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
A Case of a Derivative Chromosome: der(Y)t(Y;18)Pat with Congenital Abnormalities.
Autorzy :
Huang S; Prenatal Diagnosis Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Xia Y; Department of Cardiovascular Surgery of Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Ding H; Prenatal Diagnosis Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Wang Y; Prenatal Diagnosis Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Wu Y; Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Research Department of Medical Sciences, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Chen S; Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Research Department of Medical Sciences, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Zhuang J; Department of Cardiovascular Surgery of Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Li P; Prenatal Diagnosis Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.; Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
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Źródło :
Fetal and pediatric pathology [Fetal Pediatr Pathol] 2021 Jun; Vol. 40 (3), pp. 256-261. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Abnormalities, Multiple*/genetics
Translocation, Genetic*
Chromosome Banding ; Chromosomes ; Female ; Humans ; Infant, Newborn ; Karyotyping ; Phenotype ; Pregnancy ; Trisomy
Czasopismo naukowe
Tytuł :
Human Chromosome 18 and Acrocentrics: A Dangerous Liaison.
Autorzy :
Villa N; Medical Genetics Laboratory, Clinical Pathology Department, S. Gerardo Hospital, 20900 Monza, Italy.
Redaelli S; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Sala E; Medical Genetics Laboratory, Clinical Pathology Department, S. Gerardo Hospital, 20900 Monza, Italy.
Conconi D; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Romitti L; Pathology and Cytogenetics Laboratory, Clinical Pathology Department, Niguarda Ca' Granda Hospital, 20162 Milan, Italy.
Manfredini E; Medical Cytogenetics Laboratory, Istituto Auxologico Italiano IRCCS, 20095 Cusano Milanino, Italy.
Crosti F; Medical Genetics Laboratory, Clinical Pathology Department, S. Gerardo Hospital, 20900 Monza, Italy.
Roversi G; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Lavitrano M; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Rodeschini O; Medical Cytogenetics Laboratory, Istituto Auxologico Italiano IRCCS, 20095 Cusano Milanino, Italy.
Recalcati MP; Medical Cytogenetics Laboratory, Istituto Auxologico Italiano IRCCS, 20095 Cusano Milanino, Italy.
Piazza R; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Dalprà L; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Riva P; Medical Genetics Laboratory, Medical Biotechnology and Translational Medicine Department, University of Milan, 20090 Milan, Italy.
Bentivegna A; School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 26; Vol. 22 (11). Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Translocation, Genetic*
Chromosomes, Human, Pair 18/*genetics
Adult ; Cell Line, Tumor ; Female ; Humans ; Infant ; Male ; Pregnancy
Czasopismo naukowe
Tytuł :
Secondary cytogenetic abnormalities in core-binding factor AML harboring inv(16) vs t(8;21).
Autorzy :
Han SY; Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN.
Mrózek K; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Voutsinas J; Clinical Biostatistics, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Wu Q; Clinical Biostatistics, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Morgan EA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Vestergaard H; Mastocytosis Center and.; Department of Hematology, Odense University Hospital, Odense, Denmark.
Ohgami R; Department of Pathology, Stanford University, Stanford, CA.
Kluin PM; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Kristensen TK; Mastocytosis Center and.; Department of Pathology, Odense University Hospital, Odense, Denmark.
Pullarkat S; Department of Pathology, University of California, Los Angeles, CA.
Møller MB; Mastocytosis Center and.; Department of Pathology, Odense University Hospital, Odense, Denmark.
Schiefer AI; Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.
Baughn LB; Division of Hematopathology, Mayo Clinic, Rochester, MN.; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
Kim Y; Department of Pathology, City of Hope National Medical Center, Duarte, CA.
Czuchlewski D; Department of Pathology, University of New Mexico, Albuquerque, NM.
Hilberink JR; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Horny HP; Institute of Pathology, Ludwig-Maximilian University, Munich, Germany.
George TI; Department of Pathology, University of New Mexico, Albuquerque, NM.; Department of Pathology, University of Utah, Salt Lake City, UT.
Dolan M; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
Ku NK; Department of Pathology, University of California, Los Angeles, CA.
Arana Yi C; Department of Pathology, University of New Mexico, Albuquerque, NM.
Pullarkat V; Division of Hematology and HCT, City of Hope National Medical Center, Duarte, CA.
Kohlschmidt J; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Salhotra A; Division of Hematology and HCT, City of Hope National Medical Center, Duarte, CA.
Soma L; Clinical Reseach Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA.
Bloomfield CD; Comprehensive Cancer Center, The Ohio State University, Columbus, OH.
Chen D; Division of Hematopathology, Mayo Clinic, Rochester, MN.
Sperr WR; Division of Hematology and Hemostaseology, Department of Internal Medicine I, and.; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.
Marcucci G; Division of Hematology and HCT, City of Hope National Medical Center, Duarte, CA.
Cho C; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College; New York, NY.
Akin C; Division of Allergy and Clinical Immunology, University of Michigan, Ann Arbor, Michigan, MI.
Gotlib J; Stanford Cancer Institute, School of Medicine, Stanford University, Stanford, CA.
Broesby-Olsen S; Mastocytosis Center and.; Department of Dermatology and Allergy Centre, Odense Research Center for Anaphylaxis, Odense, Denmark.
Larson M; Division of Hematology, Oncology and Cell Therapy, Rush University, Chicago, IL.
Linden MA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
Deeg HJ; Clinical Reseach Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA.
Hoermann G; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.; Central Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Innsbruck, Innsbruck, Austria.
Perales MA; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College; New York, NY.
Hornick JL; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Litzow MR; Department of Internal Medicine and.; Division of Hematology, Mayo Clinic, Rochester, MN.
Nakamura R; Division of Hematology and HCT, City of Hope National Medical Center, Duarte, CA.
Weisdorf D; Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN.
Borthakur G; Department of Leukemia, University of Texas M.D. Anderson Cancer Center, Houston, TX; and.
Huls G; Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Valent P; Division of Hematology and Hemostaseology, Department of Internal Medicine I, and.; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.
Ustun C; Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN.; Division of Hematology, Oncology and Cell Therapy, Rush University, Chicago, IL.
Yeung CCS; Clinical Reseach Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA.
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Źródło :
Blood advances [Blood Adv] 2021 May 25; Vol. 5 (10), pp. 2481-2489.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Translocation, Genetic*
Chromosome Aberrations ; Core Binding Factors/genetics ; Female ; Humans ; Male ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Transport of Folded Proteins by the Tat System.
Autorzy :
Frain KM; The School of Biosciences, University of Kent, Canterbury, CT2 7NZ, UK.
Robinson C; The School of Biosciences, University of Kent, Canterbury, CT2 7NZ, UK.
van Dijl JM; Department of Medical Microbiology, University Medical Center Groningen, University of Groningen (UMCG), Hanzeplein 1, P.O. Box 30001, 9700 RB, Groningen, The Netherlands. .
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Źródło :
The protein journal [Protein J] 2019 Aug; Vol. 38 (4), pp. 377-388.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Escherichia coli Proteins*/chemistry
Escherichia coli Proteins*/physiology
Membrane Transport Proteins*/chemistry
Membrane Transport Proteins*/physiology
Twin-Arginine-Translocation System*/chemistry
Twin-Arginine-Translocation System*/physiology
Protein Transport/*physiology
Arginine/physiology ; Bacillus subtilis ; Cell Membrane/metabolism ; Escherichia coli ; Protein Folding ; Protein Sorting Signals/physiology ; SEC Translocation Channels/chemistry ; SEC Translocation Channels/physiology
Czasopismo naukowe
Tytuł :
Therapy-related Myeloid Leukemia With the Translocation t(8;19)(p11;q13) Leading to a KAT6A-LEUTX Fusion Gene.
Autorzy :
Panagopoulos I; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; .
Andersen K; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Ramslien LF; Department of Cancer and Hematological Diseases, Telemark Hospital, Skien, Norway.
Ikonomou IM; Department of Pathology, Oslo University Hospital, Oslo, Norway.
Micci F; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Heim S; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 1753-1760.
Typ publikacji :
Case Reports
MeSH Terms :
Chromosomes, Human, Pair 19*
Chromosomes, Human, Pair 8*
Gene Fusion*
Translocation, Genetic*
Biomarkers, Tumor/*genetics
Chemoradiotherapy/*adverse effects
Histone Acetyltransferases/*genetics
Homeodomain Proteins/*genetics
Leukemia, Myeloid, Acute/*etiology
Aged ; Female ; Gene Expression Regulation, Leukemic ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Treatment Outcome ; Uterine Cervical Neoplasms/therapy
Raport
Tytuł :
Systemic and Extraradicular Bacterial Translocation in Apical Periodontitis.
Autorzy :
Bordagaray MJ; Laboratory of Periodontal Biology, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.; Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Fernández A; Laboratory of Periodontal Biology, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.; Faculty of Dentistry, Universidad Andres Bello, Santiago, Chile.
Garrido M; Laboratory of Periodontal Biology, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.; Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Astorga J; Laboratory of Periodontal Biology, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Hoare A; Department of Pathology and Oral Medicine, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.; Laboratory of Oral Microbiology, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Hernández M; Laboratory of Periodontal Biology, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.; Department of Pathology and Oral Medicine, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
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Źródło :
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2021 Mar 19; Vol. 11, pp. 649925. Date of Electronic Publication: 2021 Mar 19 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Translocation*
Periapical Periodontitis*
Cross-Sectional Studies ; DNA, Bacterial ; Humans ; Leukocytes, Mononuclear ; Porphyromonas endodontalis
Czasopismo naukowe
Tytuł :
Current progress of research on intestinal bacterial translocation.
Autorzy :
Wang YH; State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2021 Mar; Vol. 152, pp. 104652. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Translocation*
Intestines*
Endotoxins ; Intestinal Mucosa
Czasopismo naukowe
Tytuł :
Double trouble: Bacillus depends on a functional Tat machinery to avoid severe oxidative stress and starvation upon entry into a NaCl-depleted environment.
Autorzy :
Prajapati B; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, the Netherlands.
Bernal-Cabas M; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, the Netherlands.
López-Álvarez M; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, the Netherlands.
Schaffer M; University Medicine Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, Greifswald, Germany.
Bartel J; University of Greifswald, Institute of Microbiology, Department of Microbial Proteomics, Greifswald, Germany.
Rath H; University Medicine Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, Greifswald, Germany.
Steil L; University Medicine Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, Greifswald, Germany.
Becher D; University of Greifswald, Institute of Microbiology, Department of Microbial Proteomics, Greifswald, Germany.
Völker U; University Medicine Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, Greifswald, Germany.
Mäder U; University Medicine Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, Greifswald, Germany. Electronic address: .
van Dijl JM; University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, the Netherlands. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2021 Feb; Vol. 1868 (2), pp. 118914. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacillus subtilis/*metabolism
Bacterial Proteins/*metabolism
Membrane Transport Proteins/*metabolism
Oxidative Stress/*genetics
Sodium Chloride/*metabolism
Twin-Arginine-Translocation System/*metabolism
Arginine/metabolism ; Bacillus subtilis/genetics ; Bacterial Proteins/genetics ; Cell Membrane/metabolism ; Membrane Transport Proteins/genetics ; Microbial Viability/genetics ; Mutant Proteins/metabolism ; Organisms, Genetically Modified ; Protein Transport/genetics ; Twin-Arginine-Translocation System/genetics
Czasopismo naukowe
Tytuł :
Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Autorzy :
Itskanov S; Biophysics Graduate Program, University of California, Berkeley, CA, USA.
Kuo KM; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA.
Gumbart JC; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA.; School of Physics, Georgia Institute of Technology, Atlanta, GA, USA.
Park E; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. .; California Institute for Quantitative Biosciences, University of California, Berkeley, CA, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Feb; Vol. 28 (2), pp. 162-172. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Heat-Shock Proteins*/chemistry
Heat-Shock Proteins*/metabolism
Membrane Transport Proteins*/chemistry
Membrane Transport Proteins*/metabolism
Models, Molecular*
SEC Translocation Channels*/chemistry
SEC Translocation Channels*/metabolism
Saccharomyces cerevisiae Proteins*/chemistry
Saccharomyces cerevisiae Proteins*/metabolism
Eurotiales/*metabolism
Saccharomyces cerevisiae/*metabolism
Endoplasmic Reticulum/metabolism ; Protein Processing, Post-Translational ; Protein Transport
SCR Organism :
Thermomyces lanuginosus
Czasopismo naukowe
Tytuł :
Clinical and prognostic significance of t(4;14) translocation in multiple myeloma in the era of novel agents.
Autorzy :
Sato S; Division of Hematology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-0072, Japan. .; Division of Hematology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-8533, Japan. .
Kamata W; Division of Hematology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-0072, Japan.
Okada S; Division of Hematology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-0072, Japan.
Tamai Y; Division of Hematology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-0072, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2021 Feb; Vol. 113 (2), pp. 207-213. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
Chromosomes, Human, Pair 14*
Chromosomes, Human, Pair 4*
Translocation, Genetic*
Multiple Myeloma/*genetics
Multiple Myeloma/*mortality
Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Combined Modality Therapy/adverse effects ; Combined Modality Therapy/methods ; Disease Management ; Female ; Genetic Predisposition to Disease ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Multiple Myeloma/diagnosis ; Multiple Myeloma/drug therapy ; Prognosis ; Proportional Hazards Models ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Polarity/charge as a determinant of translocase requirements for membrane protein insertion.
Autorzy :
Hariharan B; Dept. of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, United States of America.
Pross E; Institute of Biology, University of Hohenheim, Stuttgart 70599, Germany.
Soman R; Dept. of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, United States of America.
Kaushik S; Dept. of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, United States of America.
Kuhn A; Institute of Biology, University of Hohenheim, Stuttgart 70599, Germany.
Dalbey RE; Dept. of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, United States of America. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2021 Feb 01; Vol. 1863 (2), pp. 183502. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Membrane/*metabolism
Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
Membrane Transport Proteins/*metabolism
Periplasm/*metabolism
SEC Translocation Channels/*metabolism
Animals ; Cell Line ; Cell Membrane/chemistry ; Cell Membrane/genetics ; Escherichia coli/chemistry ; Escherichia coli/genetics ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Membrane Transport Proteins/chemistry ; Membrane Transport Proteins/genetics ; Mice ; Periplasm/chemistry ; Periplasm/genetics ; Protein Structure, Secondary ; SEC Translocation Channels/chemistry ; SEC Translocation Channels/genetics
Czasopismo naukowe

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