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Tytuł:
Design, synthesis and in vitro biological studies of novel triazoles with potent and broad-spectrum antifungal activity.
Autorzy:
Bao J; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Hao Y; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Ni T; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Wang R; Center of New Drug Research, School of Pharmacy, Naval Medical University, Shanghai, China.
Liu J; Center of New Drug Research, School of Pharmacy, Naval Medical University, Shanghai, China.
Chi X; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Wang T; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Yu S; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Jin Y; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Yan L; Center of New Drug Research, School of Pharmacy, Naval Medical University, Shanghai, China.
Li X; Department of Stomatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Zhang D; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Xie F; Department of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2244696.
Typ publikacji:
Journal Article
MeSH Terms:
Antifungal Agents*/chemistry
Triazoles*/chemistry
Humans ; Molecular Docking Simulation ; Fluconazole/pharmacology ; Candida albicans ; Structure-Activity Relationship ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Coordination Complexes Built from a Ditopic Triazole-Pyrazole Ligand with Antibacterial and Antifungal Performances.
Autorzy:
Draoui Y; LCAE, Department of Chemistry, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.
Radi S; LCAE, Department of Chemistry, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.
El Massaoudi M; LCAE, Department of Chemistry, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.
Bahjou Y; LCAE, Department of Chemistry, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.; Institute of Condensed Matter and Nanosciences, Molecular Chemistry, Materials and Catalysis (IMCN/MOST), Université Catholique de Louvain, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium.
Ouahhoud S; Laboratory of Biochemistry and Biotechnology, Department of Biology, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.
Mamri S; Laboratory of Biochemistry and Biotechnology, Department of Biology, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.
Ferbinteanu M; Inorganic Chemistry Department, Faculty of Chemistry, University of Bucharest, Panduri Road, No. 90, 050663 Bucharest, Romania.
Benabbes R; Laboratory of Biochemistry and Biotechnology, Department of Biology, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco.
Wolff M; Institute of Chemical Catalysis, Faculty of Chemistry, Universität Wien, Währinger Straße 38-42, 1090 Wien, Austria.
Robeyns K; Institute of Condensed Matter and Nanosciences, Molecular Chemistry, Materials and Catalysis (IMCN/MOST), Université Catholique de Louvain, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium.
Garcia Y; Institute of Condensed Matter and Nanosciences, Molecular Chemistry, Materials and Catalysis (IMCN/MOST), Université Catholique de Louvain, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Sep 25; Vol. 28 (19). Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article
MeSH Terms:
Antifungal Agents*/pharmacology
Antifungal Agents*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Ligands ; Triazoles/pharmacology ; Triazoles/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Pyrazoles/pharmacology ; Pyrazoles/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel 1,2,3-Triazole-Based Benzothiazole Derivatives: Efficient Synthesis, DFT, Molecular Docking, and ADMET Studies.
Autorzy:
Mirjafary Z; Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran 14515-775, Iran.
Mohammad Karbasi M; Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran 14515-775, Iran.
Hesamzadeh P; Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran 14515-775, Iran.
Shaker HR; Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran 14515-775, Iran.
Amiri A; Department of Science, Payame Noor University (PNU), Tehran P.O. Box 19395-4697, Iran.
Saeidian H; Department of Science, Payame Noor University (PNU), Tehran P.O. Box 19395-4697, Iran.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 05; Vol. 27 (23). Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Triazoles*/pharmacology
Triazoles*/chemistry
Antifungal Agents*/pharmacology
Molecular Docking Simulation ; Cycloaddition Reaction ; Structure-Activity Relationship ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Progress of triazole antifungal agent posaconazole in individualized therapy.
Autorzy:
Shu Y; Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering and Technology Research Center for Pediatric Drug Development, Shandong Medicine and Health Key Laboratory of Clinical Pharmacy, Jinan, China.
Shi Y; Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering and Technology Research Center for Pediatric Drug Development, Shandong Medicine and Health Key Laboratory of Clinical Pharmacy, Jinan, China.
Yang Y; Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering and Technology Research Center for Pediatric Drug Development, Shandong Medicine and Health Key Laboratory of Clinical Pharmacy, Jinan, China.
Dong Z; Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering and Technology Research Center for Pediatric Drug Development, Shandong Medicine and Health Key Laboratory of Clinical Pharmacy, Jinan, China.
Yi Q; Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering and Technology Research Center for Pediatric Drug Development, Shandong Medicine and Health Key Laboratory of Clinical Pharmacy, Jinan, China.
Shi H; Department of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering and Technology Research Center for Pediatric Drug Development, Shandong Medicine and Health Key Laboratory of Clinical Pharmacy, Jinan, China.
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Źródło:
Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2022 Dec; Vol. 47 (12), pp. 1966-1981. Date of Electronic Publication: 2022 Dec 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antifungal Agents*
Triazoles*
Humans ; Drug Interactions ; Drug Monitoring/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isavuconazole as an alternative for antifungal prophylaxis in patients with hematological malignancies: Is the signal sufficient to support clinical practice?
Autorzy:
Villalobos AP; Department of Medical Microbiology and Infectious Diseases, Max Rady School of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.; Section of Infectious Diseases, Department of Internal Medicine, Max Rady School of Medicine, The University of Manitoba, Winnipeg, Manitoba, Canada.
Bow EJ; Department of Medical Microbiology and Infectious Diseases, Max Rady School of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.; Section of Infectious Diseases, Department of Internal Medicine, Max Rady School of Medicine, The University of Manitoba, Winnipeg, Manitoba, Canada.; Section of Haematology/Oncology, Department of Internal Medicine, Max Rady School of Medicine, The University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Medical Oncology and Haematology, CancerCare Manitoba, Winnipeg, Manitoba, Canada.; Infection Control Services, CancerCare Manitoba, Winnipeg, Manitoba, Canada.
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Źródło:
Transplant infectious disease : an official journal of the Transplantation Society [Transpl Infect Dis] 2023 Apr; Vol. 25 (2), pp. e14046. Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Editorial
MeSH Terms:
Antifungal Agents*/therapeutic use
Hematologic Neoplasms*/complications
Humans ; Triazoles/therapeutic use ; Nitriles/therapeutic use
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Five-year surveillance study of clinical and environmental Triazole-Resistant Aspergillus fumigatus isolates in Iran.
Autorzy:
Khojasteh S; Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Abastabar M; Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Haghani I; Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Valadan R; Department of Immunology, Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Ghazanfari S; Department of Medical Mycology and Parasitology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Abbasi K; Department of Microbiology, Zanjan Branch, Islamic Azad University, Zanjan, Iran.
Ahangarkani F; Antimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Zarrinfar H; Department of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Khodavaisy S; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Badali H; Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.; Department of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
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Źródło:
Mycoses [Mycoses] 2023 Feb; Vol. 66 (2), pp. 98-105. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Aspergillus fumigatus*
Antifungal Agents*/pharmacology
Iran/epidemiology ; Fungal Proteins/genetics ; Drug Resistance, Fungal/genetics ; Triazoles/pharmacology ; Azoles/pharmacology ; Aspergillus ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel 1, 2, 4-Triazoles as Antifungal Agents.
Autorzy:
Kazeminejad Z; Young Researchers and Elite Club, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.
Marzi M; Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Shiroudi A; Young Researchers and Elite Club, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Kouhpayeh SA; Department of Medical Pharmacology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Farjam M; Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.; Department of Medical Pharmacology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Zarenezhad E; Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Mar 22; Vol. 2022, pp. 4584846. Date of Electronic Publication: 2022 Mar 22 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antifungal Agents*/chemistry
Antifungal Agents*/pharmacology
Triazoles*/chemistry
Triazoles*/pharmacology
Microbial Sensitivity Tests ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanistic Insights into Stereospecific Antifungal Activity of Chiral Fungicide Prothioconazole against Fusarium oxysporum F. sp. cubense .
Autorzy:
Yang X; Key Laboratory of Tropical and Subtropical Fruit Tree Research of Guangdong Province, Institution of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.; College of Horticulture, Sichuan Agricultural University, Chengdu 611130, China.
Gong R; College of Horticulture, Sichuan Agricultural University, Chengdu 611130, China.
Chu Y; Key Laboratory of Tropical and Subtropical Fruit Tree Research of Guangdong Province, Institution of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.; College of Horticulture, Sichuan Agricultural University, Chengdu 611130, China.
Liu S; Key Laboratory of Tropical and Subtropical Fruit Tree Research of Guangdong Province, Institution of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Xiang D; Key Laboratory of Tropical and Subtropical Fruit Tree Research of Guangdong Province, Institution of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Li C; Key Laboratory of Tropical and Subtropical Fruit Tree Research of Guangdong Province, Institution of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 21; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*
Antifungal Agents/*pharmacology
Fusarium/*drug effects
Sterol 14-Demethylase/*genetics
Triazoles/*pharmacology
Catalase ; Gene Expression Regulation, Fungal ; Isomerism ; Molecular Docking Simulation ; Sterol 14-Demethylase/drug effects ; Superoxide Dismutase ; Triazoles/chemistry
SCR Organism:
Fusarium oxysporum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Glucosyl-1,2,3-triazoles derived from eugenol and analogues: Synthesis, anti-Candida activity, and molecular modeling studies in CYP-51.
Autorzy:
Magalhães LS; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Reis ACC; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Nakao IA; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Péret VAC; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Reis RCFM; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Silva NC; Institute of Biomedical Sciences, Federal University of Alfenas, Alfenas, Brazil.
Dias ALT; Institute of Biomedical Sciences, Federal University of Alfenas, Alfenas, Brazil.
Carvalho DT; Pharmaceutical Sciences University, Federal University of Alfenas, Alfenas, Brazil.
Dias DF; Institute of Chemistry, Federal University of Alfenas, Alfenas, Brazil.
Brandão GC; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Braga SFP; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
Souza TB; School of Pharmacy, Federal University of Ouro Preto, Ouro Preto, Brazil.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2021 Nov; Vol. 98 (5), pp. 903-913. Date of Electronic Publication: 2021 Sep 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antifungal Agents/*chemical synthesis
Eugenol/*chemistry
Triazoles/*chemical synthesis
Antifungal Agents/pharmacology ; Apoptosis/drug effects ; Candida/drug effects ; Cell Survival/drug effects ; Drug Evaluation, Preclinical ; Fibroblasts/cytology ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Structure-Activity Relationship ; Triazoles/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Permeability of New Antifungal Fluconazole Derivatives through a Lipophilic Membrane: Experiment and Modeling.
Autorzy:
Volkova TV; G.A. Krestov Institute of Solution Chemistry RAS, 153045 Ivanovo, Russia.
Perlovich GL; G.A. Krestov Institute of Solution Chemistry RAS, 153045 Ivanovo, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 02; Vol. 28 (1). Date of Electronic Publication: 2023 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Fluconazole*/pharmacology
Antifungal Agents*/pharmacology
Triazoles ; Drug Design ; Permeability ; Solubility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dendrimer-based posaconazole nanoplatform for antifungal therapy.
Autorzy:
Tang S; Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI, USA.
Chen J; Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI, USA.
Cannon J; Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI, USA.
Cao Z; Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI, USA.
Baker JR Jr; Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI, USA.
Wang SH; Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI, USA.
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Źródło:
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 2150-2159.
Typ publikacji:
Journal Article
MeSH Terms:
Antifungal Agents/*administration & dosage
Aspergillus fumigatus/*drug effects
Dendrimers/*chemistry
Nanoparticles/*chemistry
Triazoles/*administration & dosage
Antifungal Agents/pharmacology ; Chemistry, Pharmaceutical ; Dose-Response Relationship, Drug ; Drug Carriers/chemistry ; Drug Liberation ; Imidazoles/pharmacology ; Polyethylene Glycols/chemistry ; Triazoles/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effectiveness and safety of isavuconazole prophylaxis for invasive fungal infections in the haematologic setting.
Autorzy:
Ping Y; Peking University Third Hospital, Beijing, People's Republic of China.
Hongmei J; Peking University Third Hospital, Beijing, People's Republic of China.
Bellmann C; Pfizer Pharma GmbH, Berlin, Germany.
Inês M; Patient Health Impact, Pfizer Inc, Porto Salvo, Portugal.
Macmillan T; Source Health Economics, London, UK.
Webb N; Source Health Economics, Oxford, UK.
Aram JA; Pfizer Inc, Groton, CT, USA.
Penack O; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2022 Dec; Vol. 27 (1), pp. 723-732.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Antifungal Agents*/adverse effects
Invasive Fungal Infections*/drug therapy
Invasive Fungal Infections*/etiology
Invasive Fungal Infections*/prevention & control
Adult ; Humans ; Nitriles/therapeutic use ; Pyridines ; Triazoles/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reimbursement of innovative pharmaceuticals in English and Spanish hospitals-The example of isavuconazole.
Autorzy:
Jeck J; VITIS Healthcare Group, Cologne, Germany.
Wingen-Heimann SM; VITIS Healthcare Group, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; FOM University of Applied Sciences, Essen, Germany.
Thielscher C; FOM University of Applied Sciences, Essen, Germany.
Kron A; VITIS Healthcare Group, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Network Genomic Medicine, University Hospital Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology (CIO ABCD), University of Cologne, Cologne, Germany.
Bonn J; VITIS Healthcare Group, Cologne, Germany.
Jakobs F; VITIS Healthcare Group, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Network Genomic Medicine, University Hospital Cologne, Cologne, Germany.
Grau S; Pharmacy Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain.
Enoch DA; Clinical Microbiology & Public Health Laboratory, National Infection Service, Public Health England, Addenbrookes Hospital, Cambridge, UK.
Micallef C; Pharmacy & Microbiology Departments, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Cornely OA; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology (CIO ABCD), University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.
Kron F; VITIS Healthcare Group, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; FOM University of Applied Sciences, Essen, Germany.; Faculty of Medicine and University Hospital Cologne, Center for Integrated Oncology (CIO ABCD), University of Cologne, Cologne, Germany.
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Źródło:
Mycoses [Mycoses] 2021 Oct; Vol. 64 (10), pp. 1213-1222. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antifungal Agents*/economics
Antifungal Agents*/therapeutic use
Insurance, Health, Reimbursement*
Nitriles*/economics
Nitriles*/therapeutic use
Pyridines*/economics
Pyridines*/therapeutic use
Triazoles*/economics
Triazoles*/therapeutic use
England ; Health Care Costs ; Hospitals ; Humans ; Inpatients ; Spain
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hexaconazole-Micelle Nanodelivery System Prepared Using Different Surfactants for Ganoderma Antifungal Application.
Autorzy:
Mustafa IF; Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Hussein MZ; Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Idris AS; Malaysian Palm Oil Board (MPOB), No. 6, Persiaran Institusi, Bandar Baru Bangi, Kajang 43000, Selangor, Malaysia.
Hilmi NHZ; Malaysian Palm Oil Board (MPOB), No. 6, Persiaran Institusi, Bandar Baru Bangi, Kajang 43000, Selangor, Malaysia.
Fakurazi S; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 26; Vol. 26 (19). Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Delivery Systems*
Micelles*
Antifungal Agents/*pharmacology
Ganoderma/*drug effects
Nanoparticles/*administration & dosage
Surface-Active Agents/*chemistry
Triazoles/*pharmacology
Antifungal Agents/chemistry ; Nanoparticles/chemistry ; Triazoles/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Contact Dermatitis Caused by Efinaconazole and Luliconazole.
Autorzy:
Fujimoto K; Department of Dermatology, Nippon Medical School.
Yamaguchi H; Department of Dermatology, Nippon Medical School.
Otsuka Y; Department of Dermatology, Nippon Medical School.
Mayumi N; Department of Dermatology, Nippon Medical School.
Saeki H; Department of Dermatology, Nippon Medical School.
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Źródło:
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi [J Nippon Med Sch] 2021 Jun 30; Vol. 88 (3), pp. 253-257. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Antifungal Agents/*adverse effects
Dermatitis, Contact/*etiology
Foot Dermatoses/*chemically induced
Imidazoles/*adverse effects
Triazoles/*adverse effects
Administration, Topical ; Aged ; Antifungal Agents/therapeutic use ; Epitopes ; Foot Dermatoses/drug therapy ; Humans ; Imidazoles/therapeutic use ; Male ; Patch Tests ; Triazoles/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Design, Synthesis, and Antimicrobial Activity of Certain New Indole-1,2,4 Triazole Conjugates.
Autorzy:
Al-Wabli RI; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alsulami MA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Bukhari SI; Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Moubayed NMS; Botany and Microbiology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Al-Mutairi MS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Attia MI; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), El Bohooth Street, Dokki, Giza 12622, Egypt.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 15; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Antifungal Agents/*pharmacology
Indoles/*chemistry
Triazoles/*chemistry
Triazoles/*pharmacology
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Antifungal Agents/chemical synthesis ; Antifungal Agents/chemistry ; Microbial Sensitivity Tests ; Structure-Activity Relationship ; Triazoles/chemical synthesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of Isavuconazole serum concentrations after enteral feeding tube administration in a hospitalized cohort: A case series.
Autorzy:
Spivey J; Department of Pharmacy, Duke University Hospital, Durham, NC, USA.
Wrenn R; Department of Pharmacy, Duke University Hospital, Durham, NC, USA.
Liu B; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Maziarz E; Department of Medicine (Infectious Diseases Division), Duke University Hospital, Durham, NC, USA.
Kram B; Department of Pharmacy, Duke University Hospital, Durham, NC, USA.
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Źródło:
Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2021 Apr; Vol. 46 (2), pp. 528-531. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji:
Case Reports
MeSH Terms:
Antifungal Agents/*administration & dosage
Antifungal Agents/*blood
Enteral Nutrition/*methods
Invasive Fungal Infections/*drug therapy
Nitriles/*administration & dosage
Nitriles/*blood
Pyridines/*administration & dosage
Pyridines/*blood
Triazoles/*administration & dosage
Triazoles/*blood
Adult ; Antifungal Agents/pharmacokinetics ; Drug Administration Routes ; Female ; Humans ; Male ; Middle Aged ; Nitriles/pharmacokinetics ; Pyridines/pharmacokinetics ; Triazoles/pharmacokinetics
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clinical experience with isavuconazole in healthy volunteers and patients with invasive aspergillosis in China, and the results from an exposure-response analysis.
Autorzy:
Zhang J; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Zhang Y; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Wu D; Department of Hematology, the First Affiliated Hospital of Soochow University, Suzhou, China.
Cao G; Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Hamed K; Basilea Pharmaceutica International Ltd., Basel, Switzerland.
Desai A; Astellas Pharma Inc, Northbrook, IL, USA.
Aram JA; Pfizer Inc, New York City, NY, USA.
Guo X; Pfizer Inc, Beijing, China.
Fayyad R; Pfizer Inc, New York City, NY, USA.
Cornely OA; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.; Clinical Trials Centre Cologne (ZKS Köln), Cologne, Germany.
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Źródło:
Mycoses [Mycoses] 2021 Apr; Vol. 64 (4), pp. 445-456. Date of Electronic Publication: 2021 Jan 31.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
MeSH Terms:
Antifungal Agents/*pharmacokinetics
Antifungal Agents/*therapeutic use
Aspergillosis/*drug therapy
Healthy Volunteers/*statistics & numerical data
Nitriles/*pharmacokinetics
Nitriles/*therapeutic use
Pyridines/*pharmacokinetics
Pyridines/*therapeutic use
Triazoles/*pharmacokinetics
Triazoles/*therapeutic use
Administration, Intravenous ; Administration, Oral ; Asian People ; China ; Human Experimentation ; Humans ; Invasive Fungal Infections/ethnology ; Nitriles/adverse effects ; Pyridines/adverse effects ; Treatment Outcome ; Triazoles/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent.
Autorzy:
Cass L; Pulmocide Ltd, London, UK.
Murray A; Pulmocide Ltd, London, UK.
Davis A; Pulmocide Ltd, London, UK.
Woodward K; Pulmocide Ltd, London, UK.
Albayaty M; Parexel Early Phase Clinical Unit Level 7, Northwick Park Hospital, Harrow, UK.
Ito K; Pulmocide Ltd, London, UK.
Strong P; Pulmocide Ltd, London, UK.
Ayrton J; Pulmocide Ltd, London, UK.
Brindley C; KinetAssist Limited, Quothquan, UK.
Prosser J; Pulmocide Ltd, London, UK.
Murray J; Pulmocide Ltd, London, UK.
French E; Pulmocide Ltd, London, UK.
Haywood P; Pulmocide Ltd, London, UK.
Wallis C; Pulmocide Ltd, London, UK.
Rapeport G; Pulmocide Ltd, London, UK.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2021 Feb; Vol. 9 (1), pp. e00690.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
MeSH Terms:
Antifungal Agents/*pharmacokinetics
Benzamides/*pharmacokinetics
Triazoles/*pharmacokinetics
Administration, Inhalation ; Adult ; Animals ; Antifungal Agents/adverse effects ; Antifungal Agents/blood ; Antifungal Agents/pharmacology ; Asthma/blood ; Asthma/metabolism ; Asthma/physiopathology ; Benzamides/adverse effects ; Benzamides/blood ; Benzamides/pharmacology ; Blood Proteins/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Dogs ; Double-Blind Method ; Drug Interactions ; Female ; Forced Expiratory Volume ; Humans ; Lung/metabolism ; Male ; Microsomes, Liver/metabolism ; Rats, Wistar ; Triazoles/adverse effects ; Triazoles/blood ; Triazoles/pharmacology ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Network meta-analysis of triazole, polyene, and echinocandin antifungal agents in invasive fungal infection prophylaxis in patients with hematological malignancies.
Autorzy:
Zeng H; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Wu Z; Emergency Department, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Yu B; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Wang B; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Wu C; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Wu J; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Lai J; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Gao X; Department of Hematology, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China.
Chen J; Department of Urology Surgery, the First Affiliated Hospital of Jinan University, No.613 West Huangpu street, Guangzhou, 510630, P. R. China. .
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Źródło:
BMC cancer [BMC Cancer] 2021 Apr 14; Vol. 21 (1), pp. 404. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji:
Journal Article; Meta-Analysis
MeSH Terms:
Antifungal Agents/*therapeutic use
Echinocandins/*therapeutic use
Hematologic Neoplasms/*complications
Invasive Fungal Infections/*etiology
Invasive Fungal Infections/*prevention & control
Polyenes/*therapeutic use
Triazoles/*therapeutic use
Echinocandins/administration & dosage ; Humans ; Network Meta-Analysis ; Polyenes/administration & dosage ; Pre-Exposure Prophylaxis ; Publication Bias ; Treatment Outcome ; Triazoles/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 1153

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