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Wyszukujesz frazę ""TRYPTOPHAN hydroxylase"" wg kryterium: Temat


Tytuł:
Photoperiod regulates the daily profiles of tryptophan hydroxylase-2 gene expression the raphe nuclei of rats.
Autorzy:
Malek ZS; Faculty of Pharmacy, Syrian Private University, Daraa, Syria.
Labban LM; Faculty of Pharmacy, Al Jazeera Private University, Damascus, Syria.
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Źródło:
The International journal of neuroscience [Int J Neurosci] 2021 Dec; Vol. 131 (12), pp. 1155-1161. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji:
Journal Article
MeSH Terms:
Photoperiod*
Gene Expression/*physiology
Raphe Nuclei/*metabolism
Suprachiasmatic Nucleus/*metabolism
Tryptophan Hydroxylase/*metabolism
Animals ; RNA, Messenger/metabolism ; Rats
Czasopismo naukowe
Czasopismo naukowe
Tytuł:
Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides.
Autorzy:
Bach-Mizrachi H; Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY 10032, USA.
Underwood MD
Tin A
Ellis SP
Mann JJ
Arango V
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Źródło:
Molecular psychiatry [Mol Psychiatry] 2008 May; Vol. 13 (5), pp. 507-13, 465. Date of Electronic Publication: 2008 Jan 08.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Suicide*/psychology
Depressive Disorder/*enzymology
Nerve Tissue Proteins/*physiology
Neurons/*chemistry
RNA, Messenger/*biosynthesis
Raphe Nuclei/*chemistry
Tryptophan Hydroxylase/*physiology
Adult ; Afferent Pathways/physiology ; Aged ; Case-Control Studies ; Death, Sudden ; Depressive Disorder/genetics ; Female ; Humans ; Male ; Middle Aged ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Neurons/enzymology ; Prefrontal Cortex/physiopathology ; RNA, Messenger/analysis ; Raphe Nuclei/enzymology ; Raphe Nuclei/pathology ; Serotonin/physiology ; Tryptophan Hydroxylase/biosynthesis ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł:
Adenoviral vectors for highly selective gene expression in central serotonergic neurons reveal quantal characteristics of serotonin release in the rat brain.
Autorzy:
Benzekhroufa K; Department of Physiology and Pharmacology, University of Bristol, BS8 1TD, UK. />Liu B
Tang F
Teschemacher AG
Kasparov S
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Źródło:
BMC biotechnology [BMC Biotechnol] 2009 Mar 19; Vol. 9, pp. 23. Date of Electronic Publication: 2009 Mar 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenoviridae/*genetics
Raphe Nuclei/*metabolism
Serotonin/*metabolism
Tryptophan Hydroxylase/*metabolism
Animals ; Calcium Signaling ; Exocytosis ; Gene Expression ; Genetic Vectors ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Microscopy, Confocal ; Patch-Clamp Techniques ; Rats ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł:
Tissue-specific expression of tryptophan hydroxylase mRNAs in the rat midbrain: anatomical evidence and daily profiles.
Autorzy:
Malek ZS; Laboratoire de Neurobiologie des Rythmes, UMR 7518, CNRS-ULP, Centre de Neurochimie, Strasbourg. France.
Dardente H
Pevet P
Raison S
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2005 Aug; Vol. 22 (4), pp. 895-901.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Circadian Rhythm/*physiology
Gene Expression Regulation/*physiology
Raphe Nuclei/*metabolism
Tryptophan Hydroxylase/*metabolism
Animals ; Behavior, Animal ; Cloning, Molecular/methods ; Immunohistochemistry/methods ; In Situ Hybridization/methods ; Male ; RNA, Messenger ; Raphe Nuclei/anatomy & histology ; Rats ; Rats, Wistar ; Serotonin/metabolism ; Time Factors ; Tryptophan Hydroxylase/classification ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł:
Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem.
Autorzy:
Kim JY
Kim A
Zhao ZQ
Liu XY
Chen ZF; Center for the Study of Itch, Washington University School of Medicine, St, Louis 63110, USA. .
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Źródło:
Molecular brain [Mol Brain] 2014 Jun 28; Vol. 7, pp. 48. Date of Electronic Publication: 2014 Jun 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Feedback, Physiological/*drug effects
Raphe Nuclei/*metabolism
Receptor, Serotonin, 5-HT1A/*metabolism
Serotonin/*pharmacology
Transcription Factors/*metabolism
Animals ; Animals, Newborn ; Cell Movement/drug effects ; Down-Regulation/drug effects ; GATA3 Transcription Factor/metabolism ; Mice ; Mice, Knockout ; Raphe Nuclei/drug effects ; Receptor, Serotonin, 5-HT1A/deficiency ; Serotonergic Neurons/metabolism ; Tryptophan Hydroxylase/deficiency ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Effects of chronic fluoxetine treatment on neurogenesis and tryptophan hydroxylase expression in adolescent and adult rats.
Autorzy:
Klomp A; Department of Radiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Václavů L; Swammerdam Institute of Life Sciences, Centre for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands.
Meerhoff GF; Swammerdam Institute of Life Sciences, Centre for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands.
Reneman L; Department of Radiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Lucassen PJ; Swammerdam Institute of Life Sciences, Centre for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło:
PloS one [PLoS One] 2014 May 14; Vol. 9 (5), pp. e97603. Date of Electronic Publication: 2014 May 14 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antidepressive Agents, Second-Generation/*adverse effects
Dentate Gyrus/*drug effects
Fluoxetine/*adverse effects
Hippocampus/*drug effects
Raphe Nuclei/*drug effects
Age Factors ; Animals ; Cell Proliferation/drug effects ; Dentate Gyrus/pathology ; Doublecortin Domain Proteins ; Doublecortin Protein ; Gene Expression ; Hippocampus/pathology ; Ki-67 Antigen/genetics ; Ki-67 Antigen/metabolism ; Male ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Neurogenesis/drug effects ; Neurons/drug effects ; Neurons/pathology ; Neuropeptides/genetics ; Neuropeptides/metabolism ; Raphe Nuclei/pathology ; Rats ; Rats, Wistar ; Serotonin/biosynthesis ; Tryptophan Hydroxylase/genetics ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Involvement of estrogen receptor β in maintenance of serotonergic neurons of the dorsal raphe.
Autorzy:
Suzuki H; Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77204, USA.
Barros RP
Sugiyama N
Krishnan V
Yaden BC
Kim HJ
Warner M
Gustafsson JÅ
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Źródło:
Molecular psychiatry [Mol Psychiatry] 2013 Jun; Vol. 18 (6), pp. 674-80. Date of Electronic Publication: 2012 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Estrogen Receptor beta/*metabolism
Gene Expression Regulation/*genetics
Raphe Nuclei/*cytology
Serotonergic Neurons/*physiology
Animals ; Area Under Curve ; Benzopyrans/pharmacology ; Cell Count ; Estradiol/pharmacology ; Estrogen Receptor alpha/deficiency ; Estrogen Receptor beta/agonists ; Estrogen Receptor beta/deficiency ; Female ; Gene Expression Regulation/drug effects ; Glucose Tolerance Test ; Glucose Transporter Type 4/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Skeletal/metabolism ; Ovariectomy ; Serotonin/metabolism ; Sex Characteristics ; Time Factors ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Complex regional influence of photoperiod on the nycthemeral functioning of the dorsal and median raphé serotoninergic system in the Syrian hamster.
Autorzy:
Nexon L; Département de Neurobiologie des Rythmes, Institut des Neurosciences Cellulaires et Intégratives, CNRS UPR-3212, 5 rue Blaise Pascal, 67084 Strasbourg, France.
Poirel VJ
Clesse D
Pévet P
Raison S
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2009 Nov; Vol. 30 (9), pp. 1790-801. Date of Electronic Publication: 2009 Oct 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Photoperiod*
Raphe Nuclei*/anatomy & histology
Raphe Nuclei*/physiology
Biological Clocks/*physiology
Circadian Rhythm/*physiology
Serotonin/*metabolism
Animals ; Cricetinae ; Cricetulus ; Male ; Mesocricetus/anatomy & histology ; Mesocricetus/physiology ; Tryptophan Hydroxylase/genetics ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.
Autorzy:
Gutknecht L; Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany. />Araragi N
Merker S
Waider J
Sommerlandt FM
Mlinar B
Baccini G
Mayer U
Proft F
Hamon M
Schmitt AG
Corradetti R
Lanfumey L
Lesch KP
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (8), pp. e43157. Date of Electronic Publication: 2012 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*metabolism
Gene Silencing/*physiology
Growth and Development/*physiology
Raphe Nuclei/*metabolism
Serotonin/*deficiency
Tryptophan Hydroxylase/*genetics
Age Factors ; Animals ; Autoradiography ; Body Weight ; Growth and Development/genetics ; Histological Techniques ; Hydroxyindoleacetic Acid/metabolism ; Mice ; Norepinephrine/metabolism ; Receptors, Serotonin/metabolism ; Sex Factors
Czasopismo naukowe
Tytuł:
Age-Related Alterations in the Level and Metabolism of Serotonin in the Brain of Males and Females of Annual Turquoise Killifish (Nothobranchius furzeri).
Autorzy:
Evsiukova, Valentina S. (AUTHOR)
Arefieva, Alla B. (AUTHOR)
Sorokin, Ivan E. (AUTHOR)
Kulikov, Alexander V. (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 4, p3185. 11p.
Czasopismo naukowe
Tytuł:
Serotonergic systems, anxiety, and affective disorder: focus on the dorsomedial part of the dorsal raphe nucleus.
Autorzy:
Lowry CA; Department of Integrative Physiology, University of Colorado at Boulder, Boulder, Colorado 80309-0354, USA. />Hale MW
Evans AK
Heerkens J
Staub DR
Gasser PJ
Shekhar A
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Źródło:
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2008 Dec; Vol. 1148, pp. 86-94.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Raphe Nuclei*/anatomy & histology
Raphe Nuclei*/metabolism
Anxiety/*metabolism
Mood Disorders/*metabolism
Serotonin/*metabolism
Animals ; Anxiety/physiopathology ; Corticotropin-Releasing Hormone/metabolism ; Humans ; Mood Disorders/physiopathology ; Neural Pathways/metabolism ; Stress, Physiological ; Tryptophan Hydroxylase/genetics ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Social defeat stress induces hyperthermia through activation of thermoregulatory sympathetic premotor neurons in the medullary raphe region.
Autorzy:
Lkhagvasuren B; Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nakamura Y
Oka T
Sudo N
Nakamura K
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2011 Nov; Vol. 34 (9), pp. 1442-52. Date of Electronic Publication: 2011 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dominance-Subordination*
Body Temperature Regulation/*physiology
Hypothermia/*etiology
Neurons/*physiology
Raphe Nuclei/*pathology
Stress, Psychological/*complications
Adrenergic beta-3 Receptor Antagonists/pharmacology ; Analysis of Variance ; Animals ; Anti-Anxiety Agents/pharmacology ; Body Temperature Regulation/drug effects ; Cell Count ; Cyclooxygenase Inhibitors/pharmacology ; Diazepam/pharmacology ; Disease Models, Animal ; Indomethacin/pharmacology ; Lipopolysaccharides/pharmacology ; Male ; Neurons/drug effects ; Oncogene Proteins v-fos/metabolism ; Propanolamines/pharmacology ; Rats ; Rats, Long-Evans ; Rats, Wistar ; Stress, Psychological/metabolism ; Stress, Psychological/pathology ; Tryptophan Hydroxylase/metabolism ; Vesicular Glutamate Transport Proteins/metabolism
Czasopismo naukowe
Tytuł:
Utility of organotypic raphe slice cultures to investigate the effects of sustained exposure to selective 5-HT reuptake inhibitors on 5-HT release.
Autorzy:
Nagayasu K; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto, Japan.
Yatani Y
Kitaichi M
Kitagawa Y
Shirakawa H
Nakagawa T
Kaneko S
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2010 Dec; Vol. 161 (7), pp. 1527-41.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antidepressive Agents/*pharmacology
Brain/*drug effects
Raphe Nuclei/*drug effects
Serotonin/*metabolism
Selective Serotonin Reuptake Inhibitors/*pharmacology
Action Potentials/drug effects ; Animals ; Autoreceptors/metabolism ; Brain/metabolism ; Calcium/metabolism ; Citalopram/pharmacology ; Extracellular Space/metabolism ; Fluoxetine/pharmacology ; Hydroxyindoleacetic Acid/metabolism ; Organ Culture Techniques ; Paroxetine/pharmacology ; Raphe Nuclei/metabolism ; Rats ; Rats, Wistar ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Time Factors ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Two populations of glutamatergic axons in the rat dorsal raphe nucleus defined by the vesicular glutamate transporters 1 and 2.
Autorzy:
Commons KG; University of Pennsylvania and Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, 402 Abramson Research Center, 3516 Civic Center Blvd, Philadelphia, PA 19104, USA. />Beck SG
Bey VW
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2005 Mar; Vol. 21 (6), pp. 1577-86.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Axons/*chemistry
Membrane Transport Proteins/*physiology
Raphe Nuclei/*chemistry
Animals ; Axons/enzymology ; Axons/metabolism ; Axons/ultrastructure ; Membrane Transport Proteins/biosynthesis ; Raphe Nuclei/enzymology ; Raphe Nuclei/metabolism ; Raphe Nuclei/ultrastructure ; Rats ; Tryptophan Hydroxylase/biosynthesis ; Tryptophan Hydroxylase/physiology ; Vesicular Glutamate Transport Protein 1 ; Vesicular Glutamate Transport Protein 2
Czasopismo naukowe
Tytuł:
Effects of milnacipran and fluvoxamine on hyperemotional behaviors and the loss of tryptophan hydroxylase-positive cells in olfactory bulbectomized rats.
Autorzy:
Saitoh A; Department of Pathophysiology and Therapeutics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 4-41, Ebara 2-chome, Shinagawa-ku, Tokyo, 142-8501, Japan. />Yamaguchi K
Tatsumi Y
Murasawa H
Nakatani A
Hirose N
Yamada M
Yamada M
Kamei J
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2007 May; Vol. 191 (4), pp. 857-65. Date of Electronic Publication: 2007 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Adrenergic Uptake Inhibitors/*pharmacology
Behavior, Animal/*drug effects
Cyclopropanes/*pharmacology
Emotions/*drug effects
Fluvoxamine/*pharmacology
Raphe Nuclei/*drug effects
Selective Serotonin Reuptake Inhibitors/*pharmacology
Tryptophan Hydroxylase/*metabolism
Animals ; Dose-Response Relationship, Drug ; Male ; Milnacipran ; Motor Activity/drug effects ; Neurons/drug effects ; Neurons/enzymology ; Olfactory Bulb/surgery ; Raphe Nuclei/cytology ; Raphe Nuclei/enzymology ; Rats ; Rats, Wistar ; Serotonin/metabolism ; Time Factors
Czasopismo naukowe
Tytuł:
Neurochemical identification of stereotypic burst-firing neurons in the rat dorsal raphe nucleus using juxtacellular labelling methods.
Autorzy:
Hajós M; Oxford University Department of Pharmacology, Mansfield Road, Oxford, OX2 6HE, UK. />Allers KA
Jennings K
Sharp T
Charette G
Sík A
Kocsis B
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2007 Jan; Vol. 25 (1), pp. 119-26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Chemistry*
Action Potentials/*physiology
Neurons/*physiology
Raphe Nuclei/*cytology
8-Hydroxy-2-(di-n-propylamino)tetralin/pharmacology ; Action Potentials/drug effects ; Adrenergic alpha-Antagonists/pharmacology ; Animals ; Biotin/analogs & derivatives ; Biotin/metabolism ; Dose-Response Relationship, Drug ; Immunohistochemistry/methods ; Male ; Neurons/classification ; Neurons/drug effects ; Piperazines/pharmacology ; Prazosin/pharmacology ; Pyridines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Serotonin/metabolism ; Serotonin Antagonists/pharmacology ; Serotonin Receptor Agonists/pharmacology ; Streptavidin/metabolism ; Tryptophan Hydroxylase/metabolism ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł:
Selective 5-HT receptor inhibition of glutamatergic and GABAergic synaptic activity in the rat dorsal and median raphe.
Autorzy:
Lemos JC; Department of Pediatrics, 4 North ARC, room 402 A, Children's Hospital of Philadelphia and University of Pennsylvania, 3615 Civic Center Boulevard, Philadelphia, PA 19104-4318, USA.
Pan YZ
Ma X
Lamy C
Akanwa AC
Beck SG
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2006 Dec; Vol. 24 (12), pp. 3415-30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Neurons/*metabolism
Raphe Nuclei/*cytology
Receptors, Serotonin/*physiology
Synapses/*physiology
gamma-Aminobutyric Acid/*metabolism
6-Cyano-7-nitroquinoxaline-2,3-dione/pharmacology ; Analysis of Variance ; Animals ; Bicuculline/pharmacology ; Electric Stimulation/methods ; Excitatory Amino Acid Antagonists/pharmacology ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Excitatory Postsynaptic Potentials/radiation effects ; GABA Antagonists/pharmacology ; Glutamic Acid/metabolism ; Immunohistochemistry/methods ; In Vitro Techniques ; Inhibitory Postsynaptic Potentials/drug effects ; Inhibitory Postsynaptic Potentials/physiology ; Inhibitory Postsynaptic Potentials/radiation effects ; Male ; Neurons/drug effects ; Neurons/physiology ; Neurons/radiation effects ; Patch-Clamp Techniques ; Rats ; Rats, Sprague-Dawley ; Serotonin Agents/pharmacology ; Synapses/drug effects ; Synapses/radiation effects ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł:
Immunocytochemical evidence for the existence of substance P receptor (NK1) in serotonin neurons of rat and mouse dorsal raphe nucleus.
Autorzy:
Lacoste B; Département de pathologie et biologie cellulaire, and Centre de recherche en sciences neurologiques, Faculté de médecine, Université de Montréal, Montreal, Quebec, Canada H3C 3J7.
Riad M
Descarries L
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2006 Jun; Vol. 23 (11), pp. 2947-58.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neurons/*metabolism
Raphe Nuclei/*cytology
Receptors, Neurokinin-1/*metabolism
Serotonin/*metabolism
Animals ; Cell Count/methods ; Immunohistochemistry/methods ; Male ; Mice ; Microscopy, Immunoelectron/methods ; Neurons/ultrastructure ; Rats ; Rats, Sprague-Dawley ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe

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